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Cheap flights from Detroit to Santo Domingo from $217

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santo Domingo departing on 9/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
7:00 am - 2:49 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
7h 49m1 stop Fort Lauderdale
JetBlue Logo
3:59 pm - 11:23 pmSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
7h 24m1 stop Fort Lauderdale
$451JetBlue
Sat, Sep 19 - Sat, Sep 26
JetBlue Logo
7:00 am - 2:49 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
7h 49m1 stop Fort Lauderdale
JetBlue Logo
3:59 pm - 11:23 pmSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
7h 24m1 stop Fort Lauderdale
$451JetBlue
Sat, Sep 26 - Sun, Oct 4
JetBlue Logo
7:00 am - 1:19 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
6h 19m1 stop Fort Lauderdale
JetBlue Logo
2:29 pm - 11:23 pmSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
8h 54m1 stop Fort Lauderdale
$451JetBlue
Sat, Sep 26 - Mon, Sep 28
Frontier Logo
6:42 pm - 7:04 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
23h 22m1 stop Orlando
Frontier Logo
8:19 pm - 9:19 amSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
14h 00m1 stop Orlando
$521Frontier
Wed, Dec 9 - Sun, Dec 13
Multiple Airlines Logo
4:10 pm - 11:59 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
7h 49m1 stop Fort Lauderdale
Multiple Airlines Logo
12:18 pm - 3:40 pmSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
27h 22m1 stop Philadelphia
$546Multiple Airlines
Sat, Aug 29 - Sat, Sep 5
Frontier Logo
6:42 pm - 7:04 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
23h 22m1 stop Orlando
Frontier Logo
8:19 pm - 1:43 pmSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
18h 24m2 stops Orlando Atlanta Hartsfield-Jackson
$583Frontier
Wed, Dec 9 - Sun, Dec 13
Delta Logo
9:55 pm - 1:10 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
14h 15m1 stop New York LaGuardia
Delta Logo
7:30 am - 7:01 pmSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
12h 31m1 stop New York John F Kennedy Intl
$720Delta
Wed, Jan 13 - Tue, Jan 26
Delta Logo
5:20 am - 2:40 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
8h 20m1 stop Atlanta Hartsfield-Jackson
Delta Logo
3:55 pm - 10:20 pmSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
7h 25m1 stop Atlanta Hartsfield-Jackson
$720Delta
Tue, Nov 17 - Thu, Nov 26
American Airlines Logo
12:04 pm - 10:26 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
9h 22m1 stop Miami
American Airlines Logo
1:23 pm - 11:57 pmSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
11h 34m1 stop Miami
$720American Airlines
Fri, Jan 29 - Fri, Feb 5
American Airlines Logo
6:56 pm - 2:55 pmDTW  Detroit Metropolitan Wayne County-SDQ Santo Domingo Las Americas
18h 59m1 stop Miami
American Airlines Logo
4:47 pm - 11:24 amSDQ  Santo Domingo Las Americas-DTW Detroit Metropolitan Wayne County
19h 37m1 stop Miami
$733American Airlines
Thu, Dec 10 - Tue, Jan 19

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Frontier flights from Detroit to Santo Domingo

Our best Frontier deals on Detroit to Santo Domingo flight tickets
Frontier
Dec 9
DTW6:42 pmDetroit Metropolitan Wayne County
23h 22m
1 stop
SDQ7:04 pmSanto Domingo Las Americas
Dec 13
SDQ8:19 pmSanto Domingo Las Americas
14h 00m
1 stop
DTW9:19 amDetroit Metropolitan Wayne County
$521
Frontier
Dec 9
DTW6:42 pmDetroit Metropolitan Wayne County
23h 22m
1 stop
SDQ7:04 pmSanto Domingo Las Americas
Dec 13
SDQ8:19 pmSanto Domingo Las Americas
18h 24m
2 stops
DTW1:43 pmDetroit Metropolitan Wayne County
$583
Frontier
Oct 16
DTW3:38 pmDetroit Metropolitan Wayne County
26h 14m
2 stops
SDQ5:52 pmSanto Domingo Las Americas
Oct 24
SDQ7:07 pmSanto Domingo Las Americas
14h 57m
2 stops
DTW10:04 amDetroit Metropolitan Wayne County
$591

American Airlines flights from Detroit to Santo Domingo

Our best American Airlines deals on Detroit to Santo Domingo flight tickets
American Airlines
Dec 10
DTW6:56 pmDetroit Metropolitan Wayne County
18h 59m
1 stop
SDQ2:55 pmSanto Domingo Las Americas
Jan 19
SDQ4:47 pmSanto Domingo Las Americas
19h 37m
1 stop
DTW11:24 amDetroit Metropolitan Wayne County
$733
American Airlines
Dec 10
DTW6:04 amDetroit Metropolitan Wayne County
14h 39m
2 stops
SDQ9:43 pmSanto Domingo Las Americas
Jan 19
SDQ1:23 pmSanto Domingo Las Americas
11h 34m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
$738
American Airlines
Dec 9
DTW6:00 amDetroit Metropolitan Wayne County
7h 02m
1 stop
SDQ2:02 pmSanto Domingo Las Americas
Jan 11
SDQ4:47 pmSanto Domingo Las Americas
8h 10m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
$750

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Detroit to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Sat 9/19

7:00 am-2:49 pm

1 stop7h 49m

Santo Domingo Las Americas

Sat 9/26

3:59 pm-11:23 pm

1 stop7h 24m

$451

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Sat 9/26

7:00 am-2:49 pm

1 stop7h 49m

Santo Domingo Las Americas

Sun 10/4

3:59 pm-11:23 pm

1 stop7h 24m

$451

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Sat 9/26

7:00 am-1:19 pm

1 stop6h 19m

Santo Domingo Las Americas

Mon 9/28

2:29 pm-11:23 pm

1 stop8h 54m

$451

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Wed 12/9

6:42 pm-7:04 pm

1 stop23h 22m

Santo Domingo Las Americas

Sun 12/13

8:19 pm-9:19 am

1 stop14h 00m

$521

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Sat 8/29

4:10 pm-11:59 pm

1 stop7h 49m

Santo Domingo Las Americas

Sat 9/5

12:18 pm-3:40 pm

1 stop27h 22m

$546

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Wed 12/9

6:42 pm-7:04 pm

1 stop23h 22m

Santo Domingo Las Americas

Sun 12/13

8:19 pm-1:43 pm

2 stops18h 24m

$583

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Wed 1/13

9:55 pm-1:10 pm

1 stop14h 15m

Santo Domingo Las Americas

Tue 1/26

7:30 am-7:01 pm

1 stop12h 31m

$720

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Tue 11/17

5:20 am-2:40 pm

1 stop8h 20m

Santo Domingo Las Americas

Thu 11/26

3:55 pm-10:20 pm

1 stop7h 25m

$720

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Fri 1/29

12:04 pm-10:26 pm

1 stop9h 22m

Santo Domingo Las Americas

Fri 2/5

1:23 pm-11:57 pm

1 stop11h 34m

$720

DetroitSanto Domingo

DTW Detroit Metropolitan Wayne County - SDQ Santo Domingo Las Americas

DTWSDQ

Detroit Metropolitan Wayne County

Thu 12/10

6:56 pm-2:55 pm

1 stop18h 59m

Santo Domingo Las Americas

Tue 1/19

4:47 pm-11:24 am

1 stop19h 37m

$733

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in January, then you should wait until November to fly from Detroit, when ticket prices are also cheap, with an average price of $460.

How far in advance should I book a flight from Detroit to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $616 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Detroit for as low as $346 on momondo.

When to book flights from Detroit to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santo Domingo (DTT to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santo Domingo

Fastest flight time

7h 21m

Direct flights

None
The fastest flight from Detroit to Santo Domingo takes 7h 21m
There are no direct flights from Detroit to Santo Domingo. There are no popular flight routes from Detroit to Santo Domingo.
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Frequently asked questions about flying from Detroit to Santo Domingo

  • How far is Detroit to Santo Domingo Las Americas by plane?

    A flight from Detroit to Santo Domingo Las Americas will travel around 1817.7 mi. By plane, this route typically takes 7h 21m.

  • When did momondo last update prices for flights from Detroit to Santo Domingo Las Americas Airport?

    Prices for flights from Detroit to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Detroit to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Detroit to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santo Domingo?

Best airlines flying from Detroit to Santo Domingo

Compare and see reviews for airlines that fly from Detroit to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $370Free CancellationRating
7.1
3,030 reviews
Search JetBlue flights
American AirlinesPriceFrom $638Free CancellationRating
7.1
11,897 reviews
Search American Airlines flights
DeltaPriceFrom $722Free CancellationRating
7.8
8,497 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Detroit to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Detroit to Santo Domingo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santo Domingo from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Santo Domingo?

momondo helps you find the best flight between Detroit and Santo Domingo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Santo Domingo right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Santo Domingo now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santo Domingo and let you know when they change.

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