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Cheap flights from Detroit to Santiago de los Caballeros from $139

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago de los Caballeros departing on 12/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Santiago de los Caballeros

Cheap round-trip flights

Spirit Airlines Logo
4:16 pm - 9:15 amDTW-STI
16h 59m1 stop
Spirit Airlines Logo
12:10 pm - 11:43 pmSTI-DTW
11h 33m1 stop
$307Spirit Airlines
Find Deal
Mon, Sep 1 - Tue, Sep 9
Spirit Airlines Logo
4:16 pm - 9:15 amDTW-STI
16h 59m1 stop
Spirit Airlines Logo
12:10 pm - 11:43 pmSTI-DTW
11h 33m1 stop
$317Spirit Airlines
Find Deal
Mon, Sep 1 - Tue, Sep 9
Spirit Airlines Logo
9:19 am - 11:05 amDTW-STI
25h 46m1 stop
Spirit Airlines Logo
12:10 pm - 11:43 pmSTI-DTW
11h 33m1 stop
$373Spirit Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
Logo
5:30 pm - 12:51 pmDTW-STI
19h 21m2 stops
Logo
10:20 am - 10:16 amSTI-DTW
23h 56m1 stop
$448
Find Deal
Thu, Aug 14 - Mon, Aug 18
JetBlue Logo
6:12 am - 6:04 pmDTW-STI
11h 52m1 stop
JetBlue Logo
3:20 am - 11:30 amSTI-DTW
8h 10m1 stop
$463JetBlue
Find Deal
Sat, Sep 13 - Fri, Sep 19
American Airlines Logo
5:33 am - 8:49 pmDTW-STI
14h 16m2 stops
American Airlines Logo
4:36 pm - 9:48 amSTI-DTW
18h 12m2 stops
$669American Airlines
Find Deal
Wed, Nov 26 - Mon, Dec 1
JetBlue Logo
6:05 am - 11:36 pmDTW-STI
16h 31m1 stop
JetBlue Logo
3:30 am - 11:02 pmSTI-DTW
20h 32m1 stop
$672JetBlue
Find Deal
Tue, Nov 18 - Fri, Nov 21
Delta Logo
8:38 am - 12:47 amDTW-STI
16h 09m2 stops
Delta Logo
6:03 am - 7:05 pmSTI-DTW
13h 02m2 stops
$674Delta
Find Deal
Mon, Sep 1 - Tue, Sep 9
Delta Logo
9:20 pm - 1:26 pmDTW-STI
15h 06m1 stop
Delta Logo
9:59 pm - 9:24 amSTI-DTW
12h 25m1 stop
$710Delta
Find Deal
Wed, Nov 26 - Mon, Dec 1
American Airlines Logo
6:55 am - 5:30 pmDTW-STI
9h 35m2 stops
American Airlines Logo
4:35 pm - 10:49 amSTI-DTW
19h 14m2 stops
$907American Airlines
Find Deal
Sat, Jan 3 - Wed, Jan 7

JetBlue flights from Detroit to Santiago de los Caballeros

Our best JetBlue deals on Detroit to Santiago de los Caballeros flight tickets
JetBlue
Sep 13
DTW6:12 amDetroit Metropolitan Wayne County
11h 52m
1 stop
STI6:04 pmSantiago de los Caballeros
Sep 19
STI3:20 amSantiago de los Caballeros
8h 10m
1 stop
DTW11:30 amDetroit Metropolitan Wayne County
$463
Find similar
JetBlue
Nov 18
DTW6:05 amDetroit Metropolitan Wayne County
16h 31m
1 stop
STI11:36 pmSantiago de los Caballeros
Nov 21
STI3:30 amSantiago de los Caballeros
20h 32m
1 stop
DTW11:02 pmDetroit Metropolitan Wayne County
$672
Find similar
JetBlue
Sep 1
DTW6:00 amDetroit Metropolitan Wayne County
15h 16m
1 stop
STI9:16 pmSantiago de los Caballeros
Sep 8
STI3:20 amSantiago de los Caballeros
20h 39m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$685
Find similar

Spirit Airlines flights from Detroit to Santiago de los Caballeros

Our best Spirit Airlines deals on Detroit to Santiago de los Caballeros flight tickets
Spirit Airlines
Sep 1
DTW4:16 pmDetroit Metropolitan Wayne County
16h 59m
1 stop
STI9:15 amSantiago de los Caballeros
Sep 9
STI12:10 pmSantiago de los Caballeros
11h 33m
1 stop
DTW11:43 pmDetroit Metropolitan Wayne County
$307
Find similar
Spirit Airlines
Sep 1
DTW4:16 pmDetroit Metropolitan Wayne County
16h 59m
1 stop
STI9:15 amSantiago de los Caballeros
Sep 9
STI12:10 pmSantiago de los Caballeros
11h 33m
1 stop
DTW11:43 pmDetroit Metropolitan Wayne County
$317
Find similar
Spirit Airlines
Sep 13
DTW9:19 amDetroit Metropolitan Wayne County
25h 46m
1 stop
STI11:05 amSantiago de los Caballeros
Sep 20
STI12:10 pmSantiago de los Caballeros
11h 33m
1 stop
DTW11:43 pmDetroit Metropolitan Wayne County
$373
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Detroit to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Mon 9/1

4:16 pm-9:15 am

1 stop16h 59m

Santiago de los Caballeros

Tue 9/9

12:10 pm-11:43 pm

1 stop11h 33m

$307

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Mon 9/1

4:16 pm-9:15 am

1 stop16h 59m

Santiago de los Caballeros

Tue 9/9

12:10 pm-11:43 pm

1 stop11h 33m

$317

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Sat 9/13

9:19 am-11:05 am

1 stop25h 46m

Santiago de los Caballeros

Sat 9/20

12:10 pm-11:43 pm

1 stop11h 33m

$373

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Thu 8/14

5:30 pm-12:51 pm

2 stops19h 21m

Santiago de los Caballeros

Mon 8/18

10:20 am-10:16 am

1 stop23h 56m

$448

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Sat 9/13

6:12 am-6:04 pm

1 stop11h 52m

Santiago de los Caballeros

Fri 9/19

3:20 am-11:30 am

1 stop8h 10m

$463

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Wed 11/26

5:33 am-8:49 pm

2 stops14h 16m

Santiago de los Caballeros

Mon 12/1

4:36 pm-9:48 am

2 stops18h 12m

$669

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Tue 11/18

6:05 am-11:36 pm

1 stop16h 31m

Santiago de los Caballeros

Fri 11/21

3:30 am-11:02 pm

1 stop20h 32m

$672

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Mon 9/1

8:38 am-12:47 am

2 stops16h 09m

Santiago de los Caballeros

Tue 9/9

6:03 am-7:05 pm

2 stops13h 02m

$674

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Wed 11/26

9:20 pm-1:26 pm

1 stop15h 06m

Santiago de los Caballeros

Mon 12/1

9:59 pm-9:24 am

1 stop12h 25m

$710

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Sat 1/3

6:55 am-5:30 pm

2 stops9h 35m

Santiago de los Caballeros

Wed 1/7

4:35 pm-10:49 am

2 stops19h 14m

$907

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Detroit to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Detroit to Santiago de los Caballeros is on a Tuesday when prices can be found for as low as $326. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Detroit to Santiago de los Caballeros for around $749.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Detroit to Santiago de los Caballeros flights are usually those with departure times in the afternoon. Our users have found flights to Santiago de los Caballeros in the afternoon for as low as $302. In the evening is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $749 per ticket.

When to book flights from Detroit to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago de los Caballeros (DTT to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago de los Caballeros

Best Price Found

$139

Fastest flight time

7h 23m

Direct flights

None

Airports in Santiago de los Caballeros

1 airport
The best one-way flight to Santiago de los Caballeros from Detroit in the past 72 hours is $139. The best round-trip flight deal from Detroit to Santiago de los Caballeros found on momondo in the last 72 hours is $307.
The fastest flight from Detroit to Santiago de los Caballeros takes 7h 23m
There are no direct flights from Detroit to Santiago de los Caballeros. Popular non-direct route for this connection is Detroit Metropolitan Wayne County Airport - Santiago de los Caballeros Airport.
There is 1 airport near Santiago de los Caballeros: Santiago de los Caballeros (STI)
Search flight deals

  • How far is Detroit to Santiago de los Caballeros by plane?

    The straight-line distance from Detroit to Santiago de los Caballeros is 1737.1 mi. Flights usually cover this in 9h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit to Santiago de los Caballeros Airport?

    Prices for flights from Detroit to Santiago de los Caballeros Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Detroit to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Detroit to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $411Free CancellationRating
8.0
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $445Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
JetBluePriceFrom $470Free CancellationRating
7.2
2,914 reviews
Search JetBlue flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago de los Caballeros?

It is quick and easy to find Detroit to Santiago de los Caballeros flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago de los Caballeros that suits you.

Can I find flights from Detroit to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Detroit with this policy.

How can momondo help me find flights from Detroit to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to Santiago de los Caballeros flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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