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Cheap flights from Detroit to Santiago de los Caballeros from $184

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago de los Caballeros departing on 9/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
6:00 am - 2:36 pm
DTW
-
STI
8h 36m
1 stop
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$352JetBlue
Sat, Aug 29 - Wed, Sep 2
JetBlue Logo
4:10 pm - 11:51 pm
DTW
-
STI
7h 41m
1 stop
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$411JetBlue
Wed, Sep 16 - Wed, Sep 30
JetBlue Logo
4:10 pm - 11:51 pm
DTW
-
STI
7h 41m
1 stop
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$464JetBlue
Mon, Jul 13 - Thu, Jul 16
JetBlue Logo
4:10 pm - 11:51 pm
DTW
-
STI
7h 41m
1 stop
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$474JetBlue
Fri, Jul 10 - Sun, Jul 26
JetBlue Logo
6:00 am - 2:36 pm
DTW
-
STI
8h 36m
1 stop
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$489JetBlue
Mon, Jul 20 - Mon, Jul 27
JetBlue Logo
4:10 pm - 11:51 pm
DTW
-
STI
7h 41m
1 stop
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$514JetBlue
Fri, Jul 10 - Sun, Jul 26
JetBlue Logo
6:00 am - 2:45 pm
DTW
-
STI
8h 45m
1 stop
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$535JetBlue
Tue, Sep 29 - Tue, Oct 6
JetBlue Logo
6:00 am - 2:36 pm
DTW
-
STI
8h 36m
1 stop
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$559JetBlue
Mon, Jul 20 - Sun, Aug 23
JetBlue Logo
6:00 am - 2:45 pm
DTW
-
STI
8h 45m
1 stop
JetBlue Logo
5:01 am - 9:45 pm
STI
-
DTW
16h 44m
1 stop
$577JetBlue
Wed, Sep 16 - Wed, Sep 30
JetBlue Logo
6:00 am - 6:29 pm
DTW
-
STI
12h 29m
2 stops
JetBlue Logo
5:01 am - 3:10 pm
STI
-
DTW
10h 09m
1 stop
$598JetBlue
Mon, Sep 28 - Fri, Oct 2

JetBlue flights from Detroit to Santiago de los Caballeros

Our best JetBlue deals on Detroit to Santiago de los Caballeros flight tickets
JetBlue
Aug 29
DTW6:00 amDetroit Metropolitan Wayne County
8h 36m
1 stop
STI2:36 pmSantiago de los Caballeros
Sep 2
STI5:01 amSantiago de los Caballeros
10h 09m
1 stop
DTW3:10 pmDetroit Metropolitan Wayne County
$352
JetBlue
Sep 16
DTW4:10 pmDetroit Metropolitan Wayne County
7h 41m
1 stop
STI11:51 pmSantiago de los Caballeros
Sep 30
STI5:01 amSantiago de los Caballeros
10h 09m
1 stop
DTW3:10 pmDetroit Metropolitan Wayne County
$411
JetBlue
Jul 13
DTW4:10 pmDetroit Metropolitan Wayne County
7h 41m
1 stop
STI11:51 pmSantiago de los Caballeros
Jul 16
STI5:01 amSantiago de los Caballeros
10h 09m
1 stop
DTW3:10 pmDetroit Metropolitan Wayne County
$464

American Airlines flights from Detroit to Santiago de los Caballeros

Our best American Airlines deals on Detroit to Santiago de los Caballeros flight tickets
American Airlines
Sep 16
DTW4:10 pmDetroit Metropolitan Wayne County
20h 10m
2 stops
STI12:20 pmSantiago de los Caballeros
Sep 30
STI1:40 pmSantiago de los Caballeros
8h 22m
2 stops
DTW10:02 pmDetroit Metropolitan Wayne County
$716
American Airlines
Sep 16
DTW5:39 pmDetroit Metropolitan Wayne County
18h 41m
2 stops
STI12:20 pmSantiago de los Caballeros
Sep 30
STI1:40 pmSantiago de los Caballeros
10h 13m
2 stops
DTW11:53 pmDetroit Metropolitan Wayne County
$717
American Airlines
Sep 16
DTW5:39 pmDetroit Metropolitan Wayne County
18h 41m
2 stops
STI12:20 pmSantiago de los Caballeros
Sep 30
STI1:40 pmSantiago de los Caballeros
19h 26m
2 stops
DTW9:06 amDetroit Metropolitan Wayne County
$718

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Detroit to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Sat 8/29

6:00 am-2:36 pm

1 stop8h 36m

Santiago de los Caballeros

Wed 9/2

5:01 am-3:10 pm

1 stop10h 09m

$352
Quickest round-trip

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Wed 9/16

4:10 pm-11:51 pm

1 stop7h 41m

Santiago de los Caballeros

Wed 9/30

5:01 am-3:10 pm

1 stop10h 09m

$411

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Mon 7/13

4:10 pm-11:51 pm

1 stop7h 41m

Santiago de los Caballeros

Thu 7/16

5:01 am-3:10 pm

1 stop10h 09m

$464

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Fri 7/10

4:10 pm-11:51 pm

1 stop7h 41m

Santiago de los Caballeros

Sun 7/26

5:01 am-3:10 pm

1 stop10h 09m

$474

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Mon 7/20

6:00 am-2:36 pm

1 stop8h 36m

Santiago de los Caballeros

Mon 7/27

5:01 am-3:10 pm

1 stop10h 09m

$489

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Fri 7/10

4:10 pm-11:51 pm

1 stop7h 41m

Santiago de los Caballeros

Sun 7/26

5:01 am-3:10 pm

1 stop10h 09m

$514

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Tue 9/29

6:00 am-2:45 pm

1 stop8h 45m

Santiago de los Caballeros

Tue 10/6

5:01 am-3:10 pm

1 stop10h 09m

$535

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Mon 7/20

6:00 am-2:36 pm

1 stop8h 36m

Santiago de los Caballeros

Sun 8/23

5:01 am-3:10 pm

1 stop10h 09m

$559

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Wed 9/16

6:00 am-2:45 pm

1 stop8h 45m

Santiago de los Caballeros

Wed 9/30

5:01 am-9:45 pm

1 stop16h 44m

$577

DetroitSantiago de los Caballeros

DTW - STI

DTWSTI

Detroit Metropolitan Wayne County

Mon 9/28

6:00 am-6:29 pm

2 stops12h 29m

Santiago de los Caballeros

Fri 10/2

5:01 am-3:10 pm

1 stop10h 09m

$598

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Detroit to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Detroit is in October. Flight prices, which tend to average around $338, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of October, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $353.

When to book flights from Detroit to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago de los Caballeros (DTT to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago de los Caballeros

Fastest flight time

7h 41m

Direct flights

None
The fastest flight from Detroit to Santiago de los Caballeros takes 7h 41m
There are no direct flights from Detroit to Santiago de los Caballeros. There are no popular flight routes from Detroit to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Detroit to Santiago de los Caballeros

  • How far is Detroit to Santiago de los Caballeros by plane?

    The straight-line distance from Detroit to Santiago de los Caballeros is 1737.1 mi. Flights usually cover this in 7h 41m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit to Santiago de los Caballeros Airport?

    Prices for flights from Detroit to Santiago de los Caballeros Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Detroit to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The required travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago de los Caballeros Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Detroit to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $338Free CancellationRating
6.3
8,630 reviews
Search Spirit Airlines flights
JetBluePriceFrom $434Free CancellationRating
7.1
2,973 reviews
Search JetBlue flights
American AirlinesPriceFrom $462Free CancellationRating
7.1
11,665 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago de los Caballeros?

It is quick and easy to find Detroit to Santiago de los Caballeros flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago de los Caballeros that suits you.

Can I find flights from Detroit to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Detroit with this policy.

How can momondo help me find flights from Detroit to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to Santiago de los Caballeros flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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