Which layover airport has the shortest connection time from Detroit to Santiago?

New York (JFK) has the shortest average layover time for this route: 2h 37m.

Which layover airport has the shortest travel time from Detroit to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 14h 21m.

Which layover airport offers the lowest fares from Detroit to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $863.

Which airport is the most popular layover for flights between Detroit and Santiago?

Dallas (DFW) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

As of April 2026, there are 2 operators available to choose from for flights from Detroit to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$350 Cheap Flights from Detroit to Santiago in 2026

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Find the cheapest flights from Detroit to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:50 pm - 1:30 pm

DTW

SCL

39h 40m

3 stops

12:30 am - 11:53 pm

SCL

DTW

23h 23m

2 stops

$764Multiple Airlines

Thu, May 28 - Wed, Jun 3

6:11 pm - 1:30 pm

DTW

SCL

43h 19m

3 stops

12:30 am - 7:52 am

SCL

DTW

31h 22m

3 stops

$774Multiple Airlines

Thu, May 28 - Wed, Jun 3

9:25 am - 4:45 am

DTW

SCL

19h 20m

2 stops

3:20 pm - 11:53 pm

SCL

DTW

32h 33m

2 stops

$782Multiple Airlines

Tue, May 26 - Tue, Jun 2

9:50 pm - 5:30 am

DTW

SCL

31h 40m

3 stops

3:20 pm - 11:53 pm

SCL

DTW

32h 33m

2 stops

$790Multiple Airlines

Tue, May 26 - Tue, Jun 2

9:50 pm - 5:30 am

DTW

SCL

31h 40m

3 stops

4:41 am - 11:53 pm

SCL

DTW

43h 12m

3 stops

$828Multiple Airlines

Tue, May 26 - Tue, Jun 2

6:50 am - 5:30 am

DTW

SCL

22h 40m

3 stops

12:30 am - 9:03 am

SCL

DTW

32h 33m

3 stops

$836Multiple Airlines

Sat, Apr 25 - Fri, May 8

9:50 pm - 5:30 am

DTW

SCL

31h 40m

3 stops

12:30 am - 7:52 am

SCL

DTW

31h 22m

3 stops

$844Multiple Airlines

Sat, May 30 - Fri, Jun 5

6:50 am - 5:30 am

DTW

SCL

22h 40m

3 stops

3:20 pm - 7:17 pm

SCL

DTW

27h 57m

2 stops

$852Multiple Airlines

Sat, Apr 25 - Sat, May 9

6:50 am - 5:30 am

DTW

SCL

22h 40m

3 stops

3:20 pm - 10:52 pm

SCL

DTW

31h 32m

3 stops

$860Multiple Airlines

Sat, Apr 25 - Tue, Apr 28

8:30 pm - 5:30 am

DTW

SCL

33h 00m

3 stops

3:20 pm - 11:59 pm

SCL

DTW

32h 39m

2 stops

$863Multiple Airlines

Fri, Apr 24 - Tue, Apr 28

Avianca flights from Detroit to Santiago

Our best Avianca deals on Detroit to Santiago flight tickets

Avianca

Apr 19

DTW6:00 amDetroit Metropolitan Wayne County

22h 45m

2 stops

SCL4:45 amSantiago Arturo Merino Benitez

Apr 22

SCL12:30 amSantiago Arturo Merino Benitez

18h 21m

2 stops

DTW6:51 pmDetroit Metropolitan Wayne County

$1,446

Avianca

Apr 19

DTW6:00 amDetroit Metropolitan Wayne County

22h 45m

2 stops

SCL4:45 amSantiago Arturo Merino Benitez

Apr 22

SCL12:30 amSantiago Arturo Merino Benitez

18h 21m

2 stops

DTW6:51 pmDetroit Metropolitan Wayne County

$1,802

Avianca

Apr 19

DTW6:00 amDetroit Metropolitan Wayne County

22h 45m

2 stops

SCL4:45 amSantiago Arturo Merino Benitez

Apr 22

SCL12:30 amSantiago Arturo Merino Benitez

18h 21m

2 stops

DTW6:51 pmDetroit Metropolitan Wayne County

$1,857

LATAM Airlines flights from Detroit to Santiago

Our best LATAM Airlines deals on Detroit to Santiago flight tickets

LATAM Airlines

Apr 23

DTW2:15 pmDetroit Metropolitan Wayne County

16h 40m

1 stop

SCL6:55 amSantiago Arturo Merino Benitez

Apr 26

SCL8:40 pmSantiago Arturo Merino Benitez

21h 59m

1 stop

DTW6:39 pmDetroit Metropolitan Wayne County

$1,686

LATAM Airlines

Apr 25

DTW6:17 pmDetroit Metropolitan Wayne County

12h 58m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Apr 28

SCL8:40 pmSantiago Arturo Merino Benitez

28h 04m

1 stop

DTW12:44 amDetroit Metropolitan Wayne County

$1,792

LATAM Airlines

Apr 19

DTW8:02 pmDetroit Metropolitan Wayne County

17h 43m

2 stops

SCL1:45 pmSantiago Arturo Merino Benitez

Apr 23

SCL10:55 pmSantiago Arturo Merino Benitez

16h 15m

1 stop

DTW3:10 pmDetroit Metropolitan Wayne County

$1,903

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 5/28

9:50 pm-1:30 pm

3 stops39h 40m

Santiago Arturo Merino Benitez

Wed 6/3

12:30 am-11:53 pm

2 stops23h 23m

$764

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 5/28

6:11 pm-1:30 pm

3 stops43h 19m

Santiago Arturo Merino Benitez

Wed 6/3

12:30 am-7:52 am

3 stops31h 22m

$774

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 5/26

9:25 am-4:45 am

2 stops19h 20m

Santiago Arturo Merino Benitez

Tue 6/2

3:20 pm-11:53 pm

2 stops32h 33m

$782

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 5/26

9:50 pm-5:30 am

3 stops31h 40m

Santiago Arturo Merino Benitez

Tue 6/2

3:20 pm-11:53 pm

2 stops32h 33m

$790

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 5/26

9:50 pm-5:30 am

3 stops31h 40m

Santiago Arturo Merino Benitez

Tue 6/2

4:41 am-11:53 pm

3 stops43h 12m

$828

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 4/25

6:50 am-5:30 am

3 stops22h 40m

Santiago Arturo Merino Benitez

Fri 5/8

12:30 am-9:03 am

3 stops32h 33m

$836

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 5/30

9:50 pm-5:30 am

3 stops31h 40m

Santiago Arturo Merino Benitez

Fri 6/5

12:30 am-7:52 am

3 stops31h 22m

$844

Quickest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 4/25

6:50 am-5:30 am

3 stops22h 40m

Santiago Arturo Merino Benitez

Sat 5/9

3:20 pm-7:17 pm

2 stops27h 57m

$852

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 4/25

6:50 am-5:30 am

3 stops22h 40m

Santiago Arturo Merino Benitez

Tue 4/28

3:20 pm-10:52 pm

3 stops31h 32m

$860

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 4/24

8:30 pm-5:30 am

3 stops33h 00m

Santiago Arturo Merino Benitez

Tue 4/28

3:20 pm-11:59 pm

2 stops32h 39m

$863

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Layovers

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time	18h 03m
Direct flights	None

The fastest flight from Detroit to Santiago takes 18h 03m

There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.

Search flight deals

Frequently asked questions about flying from Detroit to Santiago

How far is Detroit to Santiago Arturo Merino Benitez by plane?
The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 18h 03m.
When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?
Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.
How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?
As of April 2026, there are 2 operators available to choose from for flights from Detroit to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Detroit to Santiago?
momondo data reveals that the most frequently booked airline on the route from Detroit to Santiago is Delta, representing 100% of all bookings.

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $563	Free Cancellation	Rating 7.9 8,408 reviews		Search Delta flights
LATAM Airlines	PriceFrom $733	Free Cancellation	Rating 7.4 1,910 reviews		Search LATAM Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.