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Cheap flights from Detroit to Santiago from $285

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 1/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:07 pm - 4:00 amDTW-SCL
31h 53m2 stops
Multiple Airlines Logo
11:25 pm - 9:41 pmSCL-DTW
24h 16m1 stop
$641Multiple Airlines
Find Deal
lun., feb. 23 - mar., mar. 3
Multiple Airlines Logo
6:07 pm - 4:00 amDTW-SCL
31h 53m2 stops
Multiple Airlines Logo
11:25 pm - 9:41 pmSCL-DTW
23h 16m1 stop
$642Multiple Airlines
Find Deal
lun., feb. 23 - lun., mar. 9
Multiple Airlines Logo
5:05 am - 2:40 pmDTW-SCL
31h 35m3 stops
Multiple Airlines Logo
12:35 pm - 10:12 pmSCL-DTW
35h 37m2 stops
$645Multiple Airlines
Find Deal
lun., ene. 19 - dom., ene. 25
Multiple Airlines Logo
12:30 pm - 2:40 pmDTW-SCL
24h 10m2 stops
Multiple Airlines Logo
12:35 pm - 10:12 pmSCL-DTW
35h 37m2 stops
$646Multiple Airlines
Find Deal
lun., ene. 19 - dom., ene. 25
Multiple Airlines Logo
6:35 am - 5:30 amDTW-SCL
20h 55m2 stops
Multiple Airlines Logo
1:35 am - 10:44 pmSCL-DTW
23h 09m2 stops
$648Multiple Airlines
Find Deal
mié., ene. 21 - mar., ene. 27
Multiple Airlines Logo
6:35 am - 5:30 amDTW-SCL
20h 55m2 stops
Multiple Airlines Logo
10:35 am - 10:12 pmSCL-DTW
13h 37m1 stop
$660Multiple Airlines
Find Deal
vie., ene. 23 - lun., feb. 2
Multiple Airlines Logo
3:14 pm - 5:30 amDTW-SCL
36h 16m2 stops
Multiple Airlines Logo
11:25 pm - 9:41 pmSCL-DTW
23h 16m1 stop
$661Multiple Airlines
Find Deal
dom., feb. 22 - lun., mar. 9
Multiple Airlines Logo
5:18 pm - 3:20 pmDTW-SCL
44h 02m2 stops
Multiple Airlines Logo
10:35 am - 10:12 pmSCL-DTW
13h 37m1 stop
$663Multiple Airlines
Find Deal
lun., ene. 19 - lun., ene. 26
Multiple Airlines Logo
6:35 am - 3:20 pmDTW-SCL
30h 45m2 stops
Multiple Airlines Logo
10:35 am - 10:12 pmSCL-DTW
13h 37m1 stop
$664Multiple Airlines
Find Deal
sáb., ene. 24 - lun., feb. 2
Multiple Airlines Logo
2:47 pm - 2:40 pmDTW-SCL
45h 53m2 stops
Multiple Airlines Logo
10:35 am - 10:12 pmSCL-DTW
13h 37m1 stop
$665Multiple Airlines
Find Deal
dom., ene. 18 - lun., ene. 26

LATAM Airlines flights from Detroit to Santiago

Our best LATAM Airlines deals on Detroit to Santiago flight tickets
LATAM Airlines
Dec 5
DTW7:49 amDetroit Metropolitan Wayne County
21h 11m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Dec 13
SCL4:35 amSantiago Arturo Merino Benitez
18h 32m
2 stops
DTW9:07 pmDetroit Metropolitan Wayne County
$1,886
Find similar
LATAM Airlines
Dec 4
DTW2:43 pmDetroit Metropolitan Wayne County
14h 57m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 18
SCL11:10 pmSantiago Arturo Merino Benitez
13h 47m
1 stop
DTW10:57 amDetroit Metropolitan Wayne County
$2,479
Find similar
LATAM Airlines
Dec 4
DTW2:43 pmDetroit Metropolitan Wayne County
14h 57m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 18
SCL6:30 pmSantiago Arturo Merino Benitez
26h 19m
2 stops
DTW6:49 pmDetroit Metropolitan Wayne County
$2,481
Find similar

Air Canada flights from Detroit to Santiago

Our best Air Canada deals on Detroit to Santiago flight tickets
Air Canada
Dec 8
DTW6:15 pmDetroit Metropolitan Wayne County
16h 00m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Dec 9
SCL8:55 pmSantiago Arturo Merino Benitez
22h 40m
1 stop
DTW5:35 pmDetroit Metropolitan Wayne County
$1,166
Find similar
Air Canada
Dec 8
DTW6:15 pmDetroit Metropolitan Wayne County
16h 00m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Dec 11
SCL8:55 pmSantiago Arturo Merino Benitez
22h 40m
1 stop
DTW5:35 pmDetroit Metropolitan Wayne County
$1,176
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 2, 2025.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lun. 2/23

6:07 pm-4:00 am

2 stops31h 53m

Santiago Arturo Merino Benitez

mar. 3/3

11:25 pm-9:41 pm

1 stop24h 16m

$641

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lun. 2/23

6:07 pm-4:00 am

2 stops31h 53m

Santiago Arturo Merino Benitez

lun. 3/9

11:25 pm-9:41 pm

1 stop23h 16m

$642

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lun. 1/19

5:05 am-2:40 pm

3 stops31h 35m

Santiago Arturo Merino Benitez

dom. 1/25

12:35 pm-10:12 pm

2 stops35h 37m

$645

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lun. 1/19

12:30 pm-2:40 pm

2 stops24h 10m

Santiago Arturo Merino Benitez

dom. 1/25

12:35 pm-10:12 pm

2 stops35h 37m

$646

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mié. 1/21

6:35 am-5:30 am

2 stops20h 55m

Santiago Arturo Merino Benitez

mar. 1/27

1:35 am-10:44 pm

2 stops23h 09m

$648

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

vie. 1/23

6:35 am-5:30 am

2 stops20h 55m

Santiago Arturo Merino Benitez

lun. 2/2

10:35 am-10:12 pm

1 stop13h 37m

$660

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

dom. 2/22

3:14 pm-5:30 am

2 stops36h 16m

Santiago Arturo Merino Benitez

lun. 3/9

11:25 pm-9:41 pm

1 stop23h 16m

$661

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lun. 1/19

5:18 pm-3:20 pm

2 stops44h 02m

Santiago Arturo Merino Benitez

lun. 1/26

10:35 am-10:12 pm

1 stop13h 37m

$663

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

sáb. 1/24

6:35 am-3:20 pm

2 stops30h 45m

Santiago Arturo Merino Benitez

lun. 2/2

10:35 am-10:12 pm

1 stop13h 37m

$664

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

dom. 1/18

2:47 pm-2:40 pm

2 stops45h 53m

Santiago Arturo Merino Benitez

lun. 1/26

10:35 am-10:12 pm

1 stop13h 37m

$665

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Santiago?

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Saturday when prices can be found for as low as $932. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,272.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Detroit to Santiago when you can find flight prices for as low as $937. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,126 per ticket.

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 11% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time

12h 25m

Direct flights

None
The fastest flight from Detroit to Santiago takes 12h 25m
There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.
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  • How far is Detroit to Santiago Arturo Merino Benitez by plane?

    The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 15h 05m.

  • When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santiago?

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $733Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $822Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights
DeltaPriceFrom $873Free CancellationRating
7.9
8,009 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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