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Cheap flights from Detroit to Santiago from $284

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 1/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:47 pm - 7:00 am
DTW
-
SCL
14h 13m1 stop
Multiple Airlines Logo
10:15 pm - 10:12 pm
SCL
-
DTW
25h 57m2 stops
$696Multiple Airlines
Mon, Jan 26 - Mon, Feb 2
Multiple Airlines Logo
6:00 am - 5:35 am
DTW
-
SCL
21h 35m2 stops
Multiple Airlines Logo
10:15 pm - 10:12 pm
SCL
-
DTW
25h 57m2 stops
$723Multiple Airlines
Mon, Jan 26 - Mon, Feb 2
Multiple Airlines Logo
10:08 pm - 6:55 am
DTW
-
SCL
30h 47m1 stop
Multiple Airlines Logo
9:05 pm - 3:17 pm
SCL
-
DTW
44h 12m2 stops
$762Multiple Airlines
Sat, Jan 31 - Tue, Feb 10
Multiple Airlines Logo
8:49 am - 2:40 pm
DTW
-
SCL
27h 51m2 stops
Multiple Airlines Logo
10:35 am - 8:31 am
SCL
-
DTW
23h 56m1 stop
$816Multiple Airlines
Fri, Feb 27 - Wed, Mar 4
Multiple Airlines Logo
2:47 pm - 7:00 am
DTW
-
SCL
14h 13m1 stop
Multiple Airlines Logo
11:25 pm - 10:12 pm
SCL
-
DTW
24h 47m1 stop
$840Multiple Airlines
Mon, Jan 26 - Mon, Feb 2
Multiple Airlines Logo
5:15 am - 5:30 am
DTW
-
SCL
22h 15m2 stops
Multiple Airlines Logo
1:35 am - 9:00 pm
SCL
-
DTW
21h 25m2 stops
$859Multiple Airlines
Fri, Feb 27 - Tue, Mar 3
American Airlines Logo
1:23 pm - 8:15 am
DTW
-
SCL
16h 52m1 stop
American Airlines Logo
10:30 pm - 4:32 pm
SCL
-
DTW
20h 02m1 stop
$864American Airlines
Thu, Jan 29 - Tue, Feb 10
Multiple Airlines Logo
2:47 pm - 3:30 pm
DTW
-
SCL
22h 43m2 stops
Multiple Airlines Logo
11:25 pm - 7:57 pm
SCL
-
DTW
22h 32m1 stop
$868Multiple Airlines
Tue, Feb 10 - Tue, Feb 17
American Airlines Logo
1:08 pm - 9:00 am
DTW
-
SCL
17h 52m2 stops
American Airlines Logo
10:30 pm - 1:32 pm
SCL
-
DTW
17h 02m2 stops
$869American Airlines
Thu, Jan 29 - Tue, Feb 10
United Airlines Logo
6:10 pm - 8:50 am
DTW
-
SCL
36h 40m2 stops
United Airlines Logo
10:45 pm - 8:13 pm
SCL
-
DTW
23h 28m2 stops
$885United Airlines
Sun, Feb 15 - Mon, Feb 23

United Airlines flights from Detroit to Santiago

Our best United Airlines deals on Detroit to Santiago flight tickets
United Airlines
Jan 5
DTW4:30 pmDetroit Metropolitan Wayne County
14h 20m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Jan 19
SCL10:45 pmSantiago Arturo Merino Benitez
20h 18m
2 stops
DTW5:03 pmDetroit Metropolitan Wayne County
$859
Find similar
United Airlines
Feb 15
DTW6:10 pmDetroit Metropolitan Wayne County
36h 40m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Feb 23
SCL10:45 pmSantiago Arturo Merino Benitez
23h 28m
2 stops
DTW8:13 pmDetroit Metropolitan Wayne County
$885
Find similar
United Airlines
Jan 5
DTW4:30 pmDetroit Metropolitan Wayne County
14h 20m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Jan 19
SCL10:45 pmSantiago Arturo Merino Benitez
17h 09m
1 stop
DTW1:54 pmDetroit Metropolitan Wayne County
$1,080
Find similar

Air Canada flights from Detroit to Santiago

Our best Air Canada deals on Detroit to Santiago flight tickets
Air Canada
Jan 19
DTW6:15 pmDetroit Metropolitan Wayne County
16h 00m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Jan 23
SCL8:25 amSantiago Arturo Merino Benitez
35h 10m
2 stops
DTW5:35 pmDetroit Metropolitan Wayne County
$1,438
Find similar
Air Canada
Jan 19
DTW6:15 pmDetroit Metropolitan Wayne County
34h 35m
2 stops
SCL6:50 amSantiago Arturo Merino Benitez
Jan 23
SCL8:25 amSantiago Arturo Merino Benitez
35h 10m
2 stops
DTW5:35 pmDetroit Metropolitan Wayne County
$1,442
Find similar
Air Canada
Jan 5
DTW6:15 pmDetroit Metropolitan Wayne County
34h 35m
2 stops
SCL6:50 amSantiago Arturo Merino Benitez
Jan 7
SCL8:55 pmSantiago Arturo Merino Benitez
22h 40m
1 stop
DTW5:35 pmDetroit Metropolitan Wayne County
$1,769
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 1/26

2:47 pm-7:00 am

1 stop14h 13m

Santiago Arturo Merino Benitez

Mon 2/2

10:15 pm-10:12 pm

2 stops25h 57m

$696

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 1/26

6:00 am-5:35 am

2 stops21h 35m

Santiago Arturo Merino Benitez

Mon 2/2

10:15 pm-10:12 pm

2 stops25h 57m

$723

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 1/31

10:08 pm-6:55 am

1 stop30h 47m

Santiago Arturo Merino Benitez

Tue 2/10

9:05 pm-3:17 pm

2 stops44h 12m

$762

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 2/27

8:49 am-2:40 pm

2 stops27h 51m

Santiago Arturo Merino Benitez

Wed 3/4

10:35 am-8:31 am

1 stop23h 56m

$816

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 1/26

2:47 pm-7:00 am

1 stop14h 13m

Santiago Arturo Merino Benitez

Mon 2/2

11:25 pm-10:12 pm

1 stop24h 47m

$840

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 2/27

5:15 am-5:30 am

2 stops22h 15m

Santiago Arturo Merino Benitez

Tue 3/3

1:35 am-9:00 pm

2 stops21h 25m

$859

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/29

1:23 pm-8:15 am

1 stop16h 52m

Santiago Arturo Merino Benitez

Tue 2/10

10:30 pm-4:32 pm

1 stop20h 02m

$864

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 2/10

2:47 pm-3:30 pm

2 stops22h 43m

Santiago Arturo Merino Benitez

Tue 2/17

11:25 pm-7:57 pm

1 stop22h 32m

$868

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 1/29

1:08 pm-9:00 am

2 stops17h 52m

Santiago Arturo Merino Benitez

Tue 2/10

10:30 pm-1:32 pm

2 stops17h 02m

$869

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 2/15

6:10 pm-8:50 am

2 stops36h 40m

Santiago Arturo Merino Benitez

Mon 2/23

10:45 pm-8:13 pm

2 stops23h 28m

$885

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Saturday when prices can be found for as low as $932. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,272.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Detroit to Santiago when you can find flight prices for as low as $937. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,126 per ticket.

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 3% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time

14h 20m

Direct flights

None
The fastest flight from Detroit to Santiago takes 14h 20m
There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.
Search flight deals

  • How far is Detroit to Santiago Arturo Merino Benitez by plane?

    The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 14h 20m.

  • When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santiago?

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $733Free CancellationRating
7.5
1,895 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $808Free CancellationRating
7.2
11,071 reviews
Search American Airlines flights
DeltaPriceFrom $873Free CancellationRating
7.9
8,016 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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