Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Detroit to Santiago from $263

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 3/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Detroit to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:50 pm - 6:30 am
DTW
-
SCL
36h 40m
2 stops
Multiple Airlines Logo
10:30 am - 7:56 pm
SCL
-
DTW
33h 26m
1 stop
$585Multiple Airlines
Wed, Apr 1 - Wed, Apr 8
Multiple Airlines Logo
5:20 am - 6:40 am
DTW
-
SCL
24h 20m
2 stops
Multiple Airlines Logo
7:53 pm - 9:23 am
SCL
-
DTW
38h 30m
3 stops
$621Multiple Airlines
Sun, Mar 22 - Sun, Mar 29
Multiple Airlines Logo
4:09 pm - 5:14 am
DTW
-
SCL
36h 05m
2 stops
Multiple Airlines Logo
10:30 am - 12:20 pm
SCL
-
DTW
26h 50m
1 stop
$626Multiple Airlines
Sun, Mar 22 - Sun, Mar 29
Multiple Airlines Logo
5:20 am - 2:30 pm
DTW
-
SCL
32h 10m
2 stops
Multiple Airlines Logo
12:40 am - 11:59 pm
SCL
-
DTW
23h 19m
3 stops
$632Multiple Airlines
Wed, Apr 1 - Tue, Apr 7
Multiple Airlines Logo
5:20 am - 2:40 pm
DTW
-
SCL
32h 20m
2 stops
Multiple Airlines Logo
5:55 am - 11:59 pm
SCL
-
DTW
19h 04m
2 stops
$641Multiple Airlines
Sun, Mar 22 - Sun, Mar 29
Multiple Airlines Logo
6:05 am - 2:30 pm
DTW
-
SCL
31h 25m
3 stops
Multiple Airlines Logo
12:40 am - 11:59 pm
SCL
-
DTW
23h 19m
3 stops
$658Multiple Airlines
Wed, Apr 1 - Tue, Apr 7
Multiple Airlines Logo
9:53 pm - 7:50 am
DTW
-
SCL
32h 57m
1 stop
Multiple Airlines Logo
10:30 am - 7:56 pm
SCL
-
DTW
33h 26m
1 stop
$669Multiple Airlines
Wed, Apr 1 - Wed, Apr 8
Multiple Airlines Logo
11:23 am - 6:30 am
DTW
-
SCL
18h 07m
2 stops
Multiple Airlines Logo
8:30 am - 12:20 pm
SCL
-
DTW
27h 50m
2 stops
$680Multiple Airlines
Sat, Apr 4 - Thu, Apr 9
Multiple Airlines Logo
2:23 pm - 4:45 am
DTW
-
SCL
38h 22m
2 stops
Multiple Airlines Logo
11:00 pm - 6:44 pm
SCL
-
DTW
19h 44m
1 stop
$708Multiple Airlines
Sat, May 2 - Sat, May 9
Multiple Airlines Logo
6:00 am - 10:39 am
DTW
-
SCL
27h 39m
3 stops
Multiple Airlines Logo
6:00 am - 11:59 pm
SCL
-
DTW
18h 59m
2 stops
$719Multiple Airlines
Wed, Mar 25 - Wed, Apr 1

American Airlines flights from Detroit to Santiago

Our best American Airlines deals on Detroit to Santiago flight tickets
American Airlines
May 10
DTW10:11 amDetroit Metropolitan Wayne County
20h 54m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
May 20
SCL8:35 pmSantiago Arturo Merino Benitez
18h 53m
2 stops
DTW3:28 pmDetroit Metropolitan Wayne County
$903
American Airlines
May 10
DTW2:49 pmDetroit Metropolitan Wayne County
16h 16m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
May 20
SCL8:35 pmSantiago Arturo Merino Benitez
27h 24m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$914
American Airlines
May 10
DTW6:07 amDetroit Metropolitan Wayne County
24h 58m
1 stop
SCL7:05 amSantiago Arturo Merino Benitez
May 20
SCL8:35 pmSantiago Arturo Merino Benitez
18h 39m
2 stops
DTW3:14 pmDetroit Metropolitan Wayne County
$915

LATAM Airlines flights from Detroit to Santiago

Our best LATAM Airlines deals on Detroit to Santiago flight tickets
LATAM Airlines
Aug 4
DTW2:00 pmDetroit Metropolitan Wayne County
15h 35m
1 stop
SCL5:35 amSantiago Arturo Merino Benitez
Aug 18
SCL10:55 pmSantiago Arturo Merino Benitez
16h 08m
1 stop
DTW3:03 pmDetroit Metropolitan Wayne County
$965
LATAM Airlines
May 10
DTW10:07 amDetroit Metropolitan Wayne County
20h 43m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
May 20
SCL10:55 pmSantiago Arturo Merino Benitez
16h 11m
1 stop
DTW3:06 pmDetroit Metropolitan Wayne County
$1,068
LATAM Airlines
May 10
DTW4:36 pmDetroit Metropolitan Wayne County
14h 14m
1 stop
SCL6:50 amSantiago Arturo Merino Benitez
May 20
SCL10:55 pmSantiago Arturo Merino Benitez
16h 11m
1 stop
DTW3:06 pmDetroit Metropolitan Wayne County
$1,070

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 4/1

4:50 pm-6:30 am

2 stops36h 40m

Santiago Arturo Merino Benitez

Wed 4/8

10:30 am-7:56 pm

1 stop33h 26m

$585

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 3/22

5:20 am-6:40 am

2 stops24h 20m

Santiago Arturo Merino Benitez

Sun 3/29

7:53 pm-9:23 am

3 stops38h 30m

$621

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 3/22

4:09 pm-5:14 am

2 stops36h 05m

Santiago Arturo Merino Benitez

Sun 3/29

10:30 am-12:20 pm

1 stop26h 50m

$626

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 4/1

5:20 am-2:30 pm

2 stops32h 10m

Santiago Arturo Merino Benitez

Tue 4/7

12:40 am-11:59 pm

3 stops23h 19m

$632

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 3/22

5:20 am-2:40 pm

2 stops32h 20m

Santiago Arturo Merino Benitez

Sun 3/29

5:55 am-11:59 pm

2 stops19h 04m

$641

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 4/1

6:05 am-2:30 pm

3 stops31h 25m

Santiago Arturo Merino Benitez

Tue 4/7

12:40 am-11:59 pm

3 stops23h 19m

$658

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 4/1

9:53 pm-7:50 am

1 stop32h 57m

Santiago Arturo Merino Benitez

Wed 4/8

10:30 am-7:56 pm

1 stop33h 26m

$669

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 4/4

11:23 am-6:30 am

2 stops18h 07m

Santiago Arturo Merino Benitez

Thu 4/9

8:30 am-12:20 pm

2 stops27h 50m

$680

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 5/2

2:23 pm-4:45 am

2 stops38h 22m

Santiago Arturo Merino Benitez

Sat 5/9

11:00 pm-6:44 pm

1 stop19h 44m

$708

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 3/25

6:00 am-10:39 am

3 stops27h 39m

Santiago Arturo Merino Benitez

Wed 4/1

6:00 am-11:59 pm

2 stops18h 59m

$719

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santiago from

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Santiago?

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time

16h 00m

Direct flights

None
The fastest flight from Detroit to Santiago takes 16h 00m
There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.
Search flight deals

  • How far is Detroit to Santiago Arturo Merino Benitez by plane?

    The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 16h 00m.

  • When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santiago?

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $563Free CancellationRating
7.9
8,174 reviews
Search Delta flights
LATAM AirlinesPriceFrom $733Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 3/10
Tue 3/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chile