Cheap flights from Detroit to Santiago from $412

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 7/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
3:15 pm - 7:23 pm
DTW
-
SCL
28h 08m
2 stops
Copa Airlines Logo
2:27 am - 11:31 pm
SCL
-
DTW
21h 04m
2 stops
$1,026Copa Airlines
Tue, Jul 14 - Mon, Jul 20
Copa Airlines Logo
11:00 am - 5:03 am
DTW
-
SCL
18h 03m
2 stops
Copa Airlines Logo
12:06 am - 10:19 pm
SCL
-
DTW
22h 13m
2 stops
$1,093Copa Airlines
Sun, Jul 12 - Sat, Jul 18
Copa Airlines Logo
8:50 am - 5:03 am
DTW
-
SCL
20h 13m
2 stops
Copa Airlines Logo
2:27 am - 10:14 am
SCL
-
DTW
31h 47m
2 stops
$1,128Copa Airlines
Fri, Jul 10 - Fri, Jul 17
United Airlines Logo
7:05 pm - 5:03 am
DTW
-
SCL
33h 58m
2 stops
United Airlines Logo
2:22 am - 10:24 pm
SCL
-
DTW
20h 02m
2 stops
$1,177United Airlines
Sun, May 31 - Wed, Jun 3
American Airlines Logo
6:00 am - 7:00 am
DTW
-
SCL
25h 00m
1 stop
American Airlines Logo
9:00 pm - 3:31 pm
SCL
-
DTW
18h 31m
2 stops
$1,194American Airlines
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
10:59 am - 7:05 am
DTW
-
SCL
20h 06m
2 stops
American Airlines Logo
9:00 pm - 3:43 pm
SCL
-
DTW
18h 43m
2 stops
$1,205American Airlines
Mon, Jun 22 - Mon, Jun 29
LATAM Airlines Logo
9:22 am - 1:25 pm
DTW
-
SCL
28h 03m
2 stops
LATAM Airlines Logo
8:40 pm - 7:11 pm
SCL
-
DTW
22h 31m
1 stop
$1,218LATAM Airlines
Mon, Jun 22 - Mon, Jun 29
United Airlines Logo
9:14 am - 5:03 am
DTW
-
SCL
19h 49m
2 stops
United Airlines Logo
11:17 am - 4:07 pm
SCL
-
DTW
28h 50m
2 stops
$1,227United Airlines
Wed, Jun 3 - Sun, Jun 7
United Airlines Logo
7:00 am - 11:26 pm
DTW
-
SCL
40h 26m
2 stops
United Airlines Logo
11:17 am - 4:07 pm
SCL
-
DTW
28h 50m
2 stops
$1,272United Airlines
Wed, Jun 3 - Sun, Jun 7
American Airlines Logo
6:00 am - 7:00 am
DTW
-
SCL
25h 00m
1 stop
American Airlines Logo
9:00 pm - 4:46 pm
SCL
-
DTW
19h 46m
2 stops
$1,294American Airlines
Sun, Jul 12 - Sun, Jul 19

United Airlines flights from Detroit to Santiago

Our best United Airlines deals on Detroit to Santiago flight tickets
United Airlines
May 31
DTW7:05 pmDetroit Metropolitan Wayne County
33h 58m
2 stops
SCL5:03 amSantiago Arturo Merino Benitez
Jun 3
SCL2:22 amSantiago Arturo Merino Benitez
20h 02m
2 stops
DTW10:24 pmDetroit Metropolitan Wayne County
$1,177
United Airlines
Jun 3
DTW9:14 amDetroit Metropolitan Wayne County
19h 49m
2 stops
SCL5:03 amSantiago Arturo Merino Benitez
Jun 7
SCL11:17 amSantiago Arturo Merino Benitez
28h 50m
2 stops
DTW4:07 pmDetroit Metropolitan Wayne County
$1,227
United Airlines
Jun 3
DTW7:00 amDetroit Metropolitan Wayne County
40h 26m
2 stops
SCL11:26 pmSantiago Arturo Merino Benitez
Jun 7
SCL11:17 amSantiago Arturo Merino Benitez
28h 50m
2 stops
DTW4:07 pmDetroit Metropolitan Wayne County
$1,272

LATAM Airlines flights from Detroit to Santiago

Our best LATAM Airlines deals on Detroit to Santiago flight tickets
LATAM Airlines
Jun 22
DTW9:22 amDetroit Metropolitan Wayne County
28h 03m
2 stops
SCL1:25 pmSantiago Arturo Merino Benitez
Jun 29
SCL8:40 pmSantiago Arturo Merino Benitez
22h 31m
1 stop
DTW7:11 pmDetroit Metropolitan Wayne County
$1,218
LATAM Airlines
Jul 10
DTW6:46 pmDetroit Metropolitan Wayne County
12h 29m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
Jul 18
SCL10:55 pmSantiago Arturo Merino Benitez
16h 05m
1 stop
DTW3:00 pmDetroit Metropolitan Wayne County
$1,422
LATAM Airlines
Jul 10
DTW9:22 amDetroit Metropolitan Wayne County
20h 38m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
Jul 18
SCL10:55 pmSantiago Arturo Merino Benitez
16h 05m
1 stop
DTW3:00 pmDetroit Metropolitan Wayne County
$1,435

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 7/14

3:15 pm-7:23 pm

2 stops28h 08m

Santiago Arturo Merino Benitez

Mon 7/20

2:27 am-11:31 pm

2 stops21h 04m

$1,026

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 7/12

11:00 am-5:03 am

2 stops18h 03m

Santiago Arturo Merino Benitez

Sat 7/18

12:06 am-10:19 pm

2 stops22h 13m

$1,093

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 7/10

8:50 am-5:03 am

2 stops20h 13m

Santiago Arturo Merino Benitez

Fri 7/17

2:27 am-10:14 am

2 stops31h 47m

$1,128

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 5/31

7:05 pm-5:03 am

2 stops33h 58m

Santiago Arturo Merino Benitez

Wed 6/3

2:22 am-10:24 pm

2 stops20h 02m

$1,177

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 7/14

6:00 am-7:00 am

1 stop25h 00m

Santiago Arturo Merino Benitez

Tue 7/21

9:00 pm-3:31 pm

2 stops18h 31m

$1,194
Quickest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 6/22

10:59 am-7:05 am

2 stops20h 06m

Santiago Arturo Merino Benitez

Mon 6/29

9:00 pm-3:43 pm

2 stops18h 43m

$1,205

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 6/22

9:22 am-1:25 pm

2 stops28h 03m

Santiago Arturo Merino Benitez

Mon 6/29

8:40 pm-7:11 pm

1 stop22h 31m

$1,218

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 6/3

9:14 am-5:03 am

2 stops19h 49m

Santiago Arturo Merino Benitez

Sun 6/7

11:17 am-4:07 pm

2 stops28h 50m

$1,227

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Wed 6/3

7:00 am-11:26 pm

2 stops40h 26m

Santiago Arturo Merino Benitez

Sun 6/7

11:17 am-4:07 pm

2 stops28h 50m

$1,272

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 7/12

6:00 am-7:00 am

1 stop25h 00m

Santiago Arturo Merino Benitez

Sun 7/19

9:00 pm-4:46 pm

2 stops19h 46m

$1,294

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Detroit to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you don’t want to visit Santiago in April, then you should wait until January to fly from Detroit, when ticket prices are also cheap, with an average price of $563.

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 31% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time

16h 00m

Direct flights

None
The fastest flight from Detroit to Santiago takes 16h 00m
There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.

Frequently asked questions about flying from Detroit to Santiago

  • How far is Detroit to Santiago Arturo Merino Benitez by plane?

    The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 16h 00m.

  • When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $563Free CancellationRating
7.9
8,455 reviews
Search Delta flights
LATAM AirlinesPriceFrom $1,095Free CancellationRating
7.4
1,917 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
Pichilemu
San Fernando
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Tue 6/9
Tue 6/16

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