What airlines fly to Santiago?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to Santiago from Detroit according to our data. Delta is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

As of November 2026, there are 3 operators available to choose from for flights from Detroit to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$347 Cheap Flights from Detroit to Santiago in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:20 pm - 6:50 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

34h 30m2 stops Toronto Pearson Intl Montreal Pierre Elliott Trudeau Intl

8:25 am - 5:40 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

35h 15m2 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl

$999Air Canada

Wed, Dec 2 - Wed, Dec 9

6:20 pm - 6:50 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

34h 30m2 stops Toronto Pearson Intl Montreal Pierre Elliott Trudeau Intl

8:25 am - 5:30 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

35h 05m2 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl

$1,004Air Canada

Wed, Dec 2 - Tue, Dec 8

6:20 pm - 6:50 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

34h 30m2 stops Toronto Pearson Intl Montreal Pierre Elliott Trudeau Intl

9:55 pm - 5:30 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

21h 35m1 stop Toronto Pearson Intl

$1,010Air Canada

Wed, Dec 2 - Tue, Dec 8

11:38 am - 8:15 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

18h 37m1 stop Dallas/Fort Worth

11:15 pm - 6:35 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

21h 20m1 stop Dallas/Fort Worth

$1,206American Airlines

Tue, Dec 8 - Sun, Dec 13

8:00 am - 8:15 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

22h 15m1 stop Dallas/Fort Worth

11:15 pm - 5:23 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

20h 08m1 stop Dallas/Fort Worth

$1,206American Airlines

Mon, Dec 7 - Mon, Dec 14

4:36 pm - 8:15 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

13h 39m1 stop Dallas/Fort Worth

11:15 pm - 6:35 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

21h 20m1 stop Dallas/Fort Worth

$1,206American Airlines

Sun, Dec 6 - Sun, Dec 13

6:15 pm - 3:00 pmDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

18h 45m2 stops Miami Buenos Aires Ministro Pistarini

4:10 am - 11:33 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

21h 23m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$1,256LATAM Airlines

Mon, Dec 28 - Wed, Jan 20

10:05 am - 6:55 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

18h 50m1 stop New York John F Kennedy Intl

11:50 pm - 3:07 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

17h 17m1 stop New York John F Kennedy Intl

$1,257LATAM Airlines

Tue, Feb 16 - Mon, Mar 1

4:15 pm - 7:40 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

13h 25m1 stop Atlanta Hartsfield-Jackson

8:25 pm - 11:20 amSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

16h 55m2 stops Lima J Chavez Intl Miami

$1,272Delta

Wed, Feb 17 - Mon, Mar 1

7:15 am - 7:00 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

21h 45m1 stop Miami

8:25 pm - 11:02 amSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

16h 37m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$1,384Delta

Mon, Dec 28 - Tue, Jan 12

Cheap last minute flights

Enter your travel dates to find the best prices.

6:20 pm - 12:15 pmDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

15h 55m1 stop Toronto Pearson Intl

9:55 pm - 5:40 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

21h 45m1 stop Toronto Pearson Intl

$1,049Air Canada

Sun, Nov 15 - Tue, Dec 1

6:20 pm - 12:15 pmDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

15h 55m1 stop Toronto Pearson Intl

8:25 am - 5:40 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

35h 15m2 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl

$1,064Air Canada

Sun, Nov 15 - Tue, Dec 1

6:20 pm - 12:15 pmDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

15h 55m1 stop Toronto Pearson Intl

9:55 pm - 5:40 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

21h 45m1 stop Toronto Pearson Intl

$1,087Air Canada

Sun, Nov 15 - Tue, Dec 1

6:20 pm - 12:15 pmDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

15h 55m1 stop Toronto Pearson Intl

8:25 am - 5:40 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

35h 15m2 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl

$1,090Air Canada

Sun, Nov 15 - Tue, Dec 1

9:25 am - 9:15 pmDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

33h 50m2 stops Monterrey Gen Mariano Escobedo Mexico City Benito Juarez

8:25 am - 5:40 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

35h 15m2 stops Montreal Pierre Elliott Trudeau Intl Toronto Pearson Intl

$1,152Multiple Airlines

Sun, Nov 15 - Tue, Dec 1

6:20 pm - 12:15 pmDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

15h 55m1 stop Toronto Pearson Intl

12:20 pm - 2:05 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

27h 45m3 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl Orlando

$1,162Multiple Airlines

Sun, Nov 15 - Tue, Dec 1

9:47 am - 5:46 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

17h 59m2 stops Orlando Panama City Tocumen Intl

12:20 pm - 2:05 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

27h 45m3 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl Orlando

$1,172Multiple Airlines

Sun, Nov 15 - Tue, Dec 1

6:41 am - 5:45 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

21h 04m3 stops Atlanta Hartsfield-Jackson Tampa Bogotá El Dorado

9:55 pm - 8:45 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

24h 50m2 stops Toronto Pearson Intl Denver Intl

$1,376Multiple Airlines

Sun, Nov 15 - Tue, Dec 1

6:41 am - 5:45 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

21h 04m3 stops Atlanta Hartsfield-Jackson Tampa Bogotá El Dorado

7:30 am - 5:44 amSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

24h 14m3 stops Bogotá El Dorado San Salvador El Salvador Intl Las Vegas Harry Reid Intl

$1,600Multiple Airlines

Sun, Nov 15 - Tue, Dec 1

9:15 am - 6:55 amDTW Detroit Metropolitan Wayne County-SCL Santiago Arturo Merino Benitez

19h 40m2 stops Miami Lima J Chavez Intl

10:15 am - 10:03 pmSCL Santiago Arturo Merino Benitez-DTW Detroit Metropolitan Wayne County

13h 48m1 stop Miami

$2,480LATAM Airlines

Sun, Nov 15 - Wed, Nov 18

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LATAM Airlines flights from Detroit to Santiago

Our best LATAM Airlines deals on Detroit to Santiago flight tickets

LATAM Airlines

Dec 28

DTW6:15 pmDetroit Metropolitan Wayne County

18h 45m

2 stops

SCL3:00 pmSantiago Arturo Merino Benitez

Jan 20

SCL4:10 amSantiago Arturo Merino Benitez

21h 23m

2 stops

DTW11:33 pmDetroit Metropolitan Wayne County

$1,256

LATAM Airlines

Feb 16

DTW10:05 amDetroit Metropolitan Wayne County

18h 50m

1 stop

SCL6:55 amSantiago Arturo Merino Benitez

Mar 1

SCL11:50 pmSantiago Arturo Merino Benitez

17h 17m

1 stop

DTW3:07 pmDetroit Metropolitan Wayne County

$1,257

LATAM Airlines

Feb 16

DTW10:05 amDetroit Metropolitan Wayne County

18h 50m

1 stop

SCL6:55 amSantiago Arturo Merino Benitez

Mar 1

SCL5:55 pmSantiago Arturo Merino Benitez

19h 25m

2 stops

DTW11:20 amDetroit Metropolitan Wayne County

$1,261

United Airlines flights from Detroit to Santiago

Our best United Airlines deals on Detroit to Santiago flight tickets

United Airlines

Nov 12

DTW4:45 pmDetroit Metropolitan Wayne County

14h 05m

1 stop

SCL8:50 amSantiago Arturo Merino Benitez

Nov 18

SCL10:45 pmSantiago Arturo Merino Benitez

17h 08m

1 stop

DTW1:53 pmDetroit Metropolitan Wayne County

$2,341

United Airlines

Nov 15

DTW4:45 pmDetroit Metropolitan Wayne County

14h 05m

1 stop

SCL8:50 amSantiago Arturo Merino Benitez

Nov 18

SCL10:45 pmSantiago Arturo Merino Benitez

17h 08m

1 stop

DTW1:53 pmDetroit Metropolitan Wayne County

$2,381

United Airlines

Nov 16

DTW10:48 amDetroit Metropolitan Wayne County

20h 02m

2 stops

SCL8:50 amSantiago Arturo Merino Benitez

Nov 20

SCL10:45 pmSantiago Arturo Merino Benitez

16h 43m

2 stops

DTW1:28 pmDetroit Metropolitan Wayne County

$2,385

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Wed 12/2

6:20 pm-6:50 am

2 stops34h 30m

Santiago Arturo Merino Benitez

Wed 12/9

8:25 am-5:40 pm

2 stops35h 15m

$999

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Wed 12/2

6:20 pm-6:50 am

2 stops34h 30m

Santiago Arturo Merino Benitez

Tue 12/8

8:25 am-5:30 pm

2 stops35h 05m

$1,004

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Wed 12/2

6:20 pm-6:50 am

2 stops34h 30m

Santiago Arturo Merino Benitez

Tue 12/8

9:55 pm-5:30 pm

1 stop21h 35m

$1,010

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Tue 12/8

11:38 am-8:15 am

1 stop18h 37m

Santiago Arturo Merino Benitez

Sun 12/13

11:15 pm-6:35 pm

1 stop21h 20m

$1,206

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Mon 12/7

8:00 am-8:15 am

1 stop22h 15m

Santiago Arturo Merino Benitez

Mon 12/14

11:15 pm-5:23 pm

1 stop20h 08m

$1,206

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Sun 12/6

4:36 pm-8:15 am

1 stop13h 39m

Santiago Arturo Merino Benitez

Sun 12/13

11:15 pm-6:35 pm

1 stop21h 20m

$1,206

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Mon 12/28

6:15 pm-3:00 pm

2 stops18h 45m

Santiago Arturo Merino Benitez

Wed 1/20

4:10 am-11:33 pm

2 stops21h 23m

$1,256

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Tue 2/16

10:05 am-6:55 am

1 stop18h 50m

Santiago Arturo Merino Benitez

Mon 3/1

11:50 pm-3:07 pm

1 stop17h 17m

$1,257

Quickest round-trip

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Wed 2/17

4:15 pm-7:40 am

1 stop13h 25m

Santiago Arturo Merino Benitez

Mon 3/1

8:25 pm-11:20 am

2 stops16h 55m

$1,272

DetroitSantiago

DTW Detroit Metropolitan Wayne County - SCL Santiago Arturo Merino Benitez

DTWSCL

Detroit Metropolitan Wayne County

Mon 12/28

7:15 am-7:00 am

1 stop21h 45m

Santiago Arturo Merino Benitez

Tue 1/12

8:25 pm-11:02 am

2 stops16h 37m

$1,384

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 25% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Best Price Found	$347
Fastest flight time	14h 05m
Direct flights	None

The best one-way flight to Santiago from Detroit in the past 72 hours is $347. The best round-trip flight deal from Detroit to Santiago found on momondo in the last 72 hours is $999.

The fastest flight from Detroit to Santiago takes 14h 05m

There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.

Search flight deals

Frequently asked questions about flying from Detroit to Santiago

How far is Detroit to Santiago Arturo Merino Benitez by plane?
The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 14h 05m.
When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?
Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.
How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?
As of November 2026, there are 3 operators available to choose from for flights from Detroit to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $563	Free Cancellation	Rating 7.8 8,698 reviews	Search Delta flights
American Airlines	PriceFrom $1,024	Free Cancellation	Rating 7.0 12,230 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $1,280	Free Cancellation	Rating 7.4 1,972 reviews	Search LATAM Airlines flights

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Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.