Which airport is the most popular layover for flights between Detroit and Santiago?

Dallas (DFW) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Detroit to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 14h 21m.

Which layover airport has the shortest connection time from Detroit to Santiago?

New York (JFK) has the shortest average layover time for this route: 2h 37m.

What is the cheapest airline that flies from Detroit to Santiago Arturo Merino Benitez?

American Airlines is the most popular carrier operating from Detroit to Santiago Arturo Merino Benitez

Which layover airport offers the lowest fares from Detroit to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $863.

When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

As of March 2026, there are 2 operators available to choose from for flights from Detroit to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$349 Cheap Flights from Detroit to Santiago in 2026

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Find the cheapest flights from Detroit to Santiago

Round-trip

One-way

Cheap round-trip flights

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7:58 pm - 12:11 am

DTW

SCL

28h 13m

2 stops

3:30 pm - 11:59 pm

SCL

DTW

32h 29m

3 stops

$820Multiple Airlines

sön, maj 17 - fre, maj 22

6:50 am - 4:45 am

DTW

SCL

21h 55m

3 stops

12:30 am - 12:39 am

SCL

DTW

24h 09m

3 stops

$841Multiple Airlines

tis, maj 5 - mån, maj 11

6:05 am - 4:17 am

DTW

SCL

22h 12m

3 stops

3:30 pm - 11:59 pm

SCL

DTW

32h 29m

3 stops

$849Multiple Airlines

sön, maj 17 - fre, maj 22

5:25 pm - 4:45 am

DTW

SCL

35h 20m

2 stops

3:20 pm - 7:02 pm

SCL

DTW

27h 42m

3 stops

$858Multiple Airlines

sön, apr 19 - tors, apr 30

7:58 pm - 12:11 am

DTW

SCL

28h 13m

2 stops

3:20 pm - 11:59 pm

SCL

DTW

32h 39m

2 stops

$859Multiple Airlines

sön, maj 17 - fre, maj 22

10:05 am - 3:15 pm

DTW

SCL

28h 10m

2 stops

6:40 am - 12:20 pm

SCL

DTW

29h 40m

2 stops

$883Multiple Airlines

fre, apr 3 - mån, apr 6

10:05 am - 5:45 am

DTW

SCL

18h 40m

2 stops

3:20 pm - 10:37 pm

SCL

DTW

31h 17m

3 stops

$888Multiple Airlines

fre, apr 3 - mån, apr 6

8:30 pm - 2:15 pm

DTW

SCL

41h 45m

3 stops

3:20 pm - 7:02 pm

SCL

DTW

27h 42m

3 stops

$889Multiple Airlines

sön, apr 19 - tors, apr 30

6:50 am - 4:45 am

DTW

SCL

21h 55m

3 stops

3:20 pm - 11:59 pm

SCL

DTW

32h 39m

2 stops

$909Multiple Airlines

lör, maj 16 - tis, maj 26

6:50 am - 2:15 pm

DTW

SCL

31h 25m

3 stops

3:20 pm - 10:52 pm

SCL

DTW

31h 32m

3 stops

$923Multiple Airlines

lör, maj 16 - tis, maj 26

American Airlines flights from Detroit to Santiago

Our best American Airlines deals on Detroit to Santiago flight tickets

American Airlines

May 5

DTW6:07 amDetroit Metropolitan Wayne County

24h 58m

1 stop

SCL7:05 amSantiago Arturo Merino Benitez

May 12

SCL8:35 pmSantiago Arturo Merino Benitez

19h 56m

2 stops

DTW4:31 pmDetroit Metropolitan Wayne County

$975

American Airlines

May 16

DTW2:11 pmDetroit Metropolitan Wayne County

16h 54m

2 stops

SCL7:05 amSantiago Arturo Merino Benitez

May 26

SCL9:00 pmSantiago Arturo Merino Benitez

18h 28m

2 stops

DTW3:28 pmDetroit Metropolitan Wayne County

$1,013

American Airlines

May 16

DTW5:36 pmDetroit Metropolitan Wayne County

13h 29m

1 stop

SCL7:05 amSantiago Arturo Merino Benitez

May 26

SCL9:00 pmSantiago Arturo Merino Benitez

25h 57m

1 stop

DTW10:57 pmDetroit Metropolitan Wayne County

$1,020

United Airlines flights from Detroit to Santiago

Our best United Airlines deals on Detroit to Santiago flight tickets

United Airlines

May 5

DTW9:00 amDetroit Metropolitan Wayne County

18h 00m

2 stops

SCL3:00 amSantiago Arturo Merino Benitez

May 12

SCL4:41 amSantiago Arturo Merino Benitez

43h 06m

2 stops

DTW11:47 pmDetroit Metropolitan Wayne County

$961

United Airlines

May 18

DTW9:00 amDetroit Metropolitan Wayne County

20h 10m

2 stops

SCL5:10 amSantiago Arturo Merino Benitez

May 20

SCL12:38 amSantiago Arturo Merino Benitez

21h 46m

2 stops

DTW10:24 pmDetroit Metropolitan Wayne County

$976

United Airlines

Apr 19

DTW9:00 amDetroit Metropolitan Wayne County

37h 43m

2 stops

SCL10:43 pmSantiago Arturo Merino Benitez

Apr 30

SCL4:49 amSantiago Arturo Merino Benitez

42h 58m

2 stops

DTW11:47 pmDetroit Metropolitan Wayne County

$983

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

sön 5/17

7:58 pm-12:11 am

2 stops28h 13m

Santiago Arturo Merino Benitez

fre 5/22

3:30 pm-11:59 pm

3 stops32h 29m

$820

Quickest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

tis 5/5

6:50 am-4:45 am

3 stops21h 55m

Santiago Arturo Merino Benitez

mån 5/11

12:30 am-12:39 am

3 stops24h 09m

$841

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

sön 5/17

6:05 am-4:17 am

3 stops22h 12m

Santiago Arturo Merino Benitez

fre 5/22

3:30 pm-11:59 pm

3 stops32h 29m

$849

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

sön 4/19

5:25 pm-4:45 am

2 stops35h 20m

Santiago Arturo Merino Benitez

tors 4/30

3:20 pm-7:02 pm

3 stops27h 42m

$858

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

sön 5/17

7:58 pm-12:11 am

2 stops28h 13m

Santiago Arturo Merino Benitez

fre 5/22

3:20 pm-11:59 pm

2 stops32h 39m

$859

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

fre 4/3

10:05 am-3:15 pm

2 stops28h 10m

Santiago Arturo Merino Benitez

mån 4/6

6:40 am-12:20 pm

2 stops29h 40m

$883

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

fre 4/3

10:05 am-5:45 am

2 stops18h 40m

Santiago Arturo Merino Benitez

mån 4/6

3:20 pm-10:37 pm

3 stops31h 17m

$888

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

sön 4/19

8:30 pm-2:15 pm

3 stops41h 45m

Santiago Arturo Merino Benitez

tors 4/30

3:20 pm-7:02 pm

3 stops27h 42m

$889

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lör 5/16

6:50 am-4:45 am

3 stops21h 55m

Santiago Arturo Merino Benitez

tis 5/26

3:20 pm-11:59 pm

2 stops32h 39m

$909

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lör 5/16

6:50 am-2:15 pm

3 stops31h 25m

Santiago Arturo Merino Benitez

tis 5/26

3:20 pm-10:52 pm

3 stops31h 32m

$923

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time	16h 00m
Direct flights	None

The fastest flight from Detroit to Santiago takes 16h 00m

There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.

Search flight deals

How far is Detroit to Santiago Arturo Merino Benitez by plane?
The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 16h 00m.
When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?
Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.
How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?
As of March 2026, there are 2 operators available to choose from for flights from Detroit to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Detroit to Santiago?
momondo data reveals that the most frequently booked airline on the route from Detroit to Santiago is Delta, representing 54% of all bookings. The subsequent popular airline is LATAM Airlines at 46%.

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $563	Free Cancellation	Rating 7.9 8,318 reviews		Search Delta flights
LATAM Airlines	PriceFrom $733	Free Cancellation	Rating 7.4 1,911 reviews		Search LATAM Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.