Cheap flights from Detroit to Santiago from $572

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 3/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:20 am - 2:40 pm
DTW
-
SCL
32h 20m
2 stops
Multiple Airlines Logo
5:50 am - 11:59 pm
SCL
-
DTW
19h 09m
2 stops
$572Multiple Airlines
Sun, Mar 22 - Fri, Mar 27
Multiple Airlines Logo
5:20 am - 12:00 pm
DTW
-
SCL
29h 40m
3 stops
Multiple Airlines Logo
5:50 am - 11:59 pm
SCL
-
DTW
19h 09m
2 stops
$582Multiple Airlines
Sun, Mar 22 - Fri, Mar 27
Multiple Airlines Logo
5:20 am - 12:00 pm
DTW
-
SCL
29h 40m
3 stops
Multiple Airlines Logo
1:35 am - 11:59 pm
SCL
-
DTW
23h 24m
3 stops
$593Multiple Airlines
Sun, Mar 22 - Thu, Mar 26
Multiple Airlines Logo
4:50 pm - 2:40 pm
DTW
-
SCL
44h 50m
2 stops
Multiple Airlines Logo
10:30 am - 11:59 pm
SCL
-
DTW
14h 29m
1 stop
$611Multiple Airlines
Sun, Mar 22 - Fri, Mar 27
Multiple Airlines Logo
4:50 pm - 2:40 pm
DTW
-
SCL
44h 50m
2 stops
Multiple Airlines Logo
10:30 am - 11:59 pm
SCL
-
DTW
14h 29m
1 stop
$621Multiple Airlines
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
5:20 am - 2:40 pm
DTW
-
SCL
32h 20m
3 stops
Multiple Airlines Logo
9:05 pm - 11:59 pm
SCL
-
DTW
27h 54m
2 stops
$642Multiple Airlines
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
5:20 am - 3:35 am
DTW
-
SCL
21h 15m
2 stops
Multiple Airlines Logo
9:05 pm - 11:59 pm
SCL
-
DTW
27h 54m
2 stops
$676Multiple Airlines
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
5:20 am - 2:40 pm
DTW
-
SCL
32h 20m
3 stops
Multiple Airlines Logo
12:35 pm - 10:37 pm
SCL
-
DTW
35h 02m
3 stops
$683Multiple Airlines
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
10:10 pm - 4:45 am
DTW
-
SCL
30h 35m
2 stops
Multiple Airlines Logo
8:30 am - 6:44 pm
SCL
-
DTW
34h 14m
2 stops
$689Multiple Airlines
Sun, Apr 26 - Sat, May 2
Multiple Airlines Logo
1:28 pm - 3:55 am
DTW
-
SCL
38h 27m
2 stops
Multiple Airlines Logo
8:30 am - 6:44 pm
SCL
-
DTW
34h 14m
2 stops
$694Multiple Airlines
Sat, Apr 25 - Sat, May 2

United Airlines flights from Detroit to Santiago

Our best United Airlines deals on Detroit to Santiago flight tickets
United Airlines
Mar 23
DTW10:55 amDetroit Metropolitan Wayne County
19h 55m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Mar 25
SCL9:45 pmSantiago Arturo Merino Benitez
19h 16m
1 stop
DTW4:01 pmDetroit Metropolitan Wayne County
$873
United Airlines
Mar 23
DTW1:52 pmDetroit Metropolitan Wayne County
16h 58m
2 stops
SCL7:50 amSantiago Arturo Merino Benitez
Mar 25
SCL9:45 pmSantiago Arturo Merino Benitez
20h 59m
2 stops
DTW5:44 pmDetroit Metropolitan Wayne County
$878
United Airlines
Jul 30
DTW6:25 amDetroit Metropolitan Wayne County
22h 38m
2 stops
SCL5:03 amSantiago Arturo Merino Benitez
Aug 10
SCL11:22 amSantiago Arturo Merino Benitez
22h 09m
2 stops
DTW9:31 amDetroit Metropolitan Wayne County
$928

American Airlines flights from Detroit to Santiago

Our best American Airlines deals on Detroit to Santiago flight tickets
American Airlines
May 10
DTW12:01 pmDetroit Metropolitan Wayne County
19h 04m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
May 20
SCL8:35 pmSantiago Arturo Merino Benitez
19h 05m
2 stops
DTW3:40 pmDetroit Metropolitan Wayne County
$903
American Airlines
May 10
DTW2:50 pmDetroit Metropolitan Wayne County
16h 15m
2 stops
SCL7:05 amSantiago Arturo Merino Benitez
May 20
SCL8:35 pmSantiago Arturo Merino Benitez
27h 20m
1 stop
DTW11:55 pmDetroit Metropolitan Wayne County
$914
American Airlines
Aug 5
DTW3:10 pmDetroit Metropolitan Wayne County
15h 40m
2 stops
SCL6:50 amSantiago Arturo Merino Benitez
Aug 12
SCL8:30 pmSantiago Arturo Merino Benitez
18h 46m
2 stops
DTW3:16 pmDetroit Metropolitan Wayne County
$930

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 19, 2026.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 3/22

5:20 am-2:40 pm

2 stops32h 20m

Santiago Arturo Merino Benitez

Fri 3/27

5:50 am-11:59 pm

2 stops19h 09m

$572

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 3/22

5:20 am-12:00 pm

3 stops29h 40m

Santiago Arturo Merino Benitez

Fri 3/27

5:50 am-11:59 pm

2 stops19h 09m

$582

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 3/22

5:20 am-12:00 pm

3 stops29h 40m

Santiago Arturo Merino Benitez

Thu 3/26

1:35 am-11:59 pm

3 stops23h 24m

$593

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 3/22

4:50 pm-2:40 pm

2 stops44h 50m

Santiago Arturo Merino Benitez

Fri 3/27

10:30 am-11:59 pm

1 stop14h 29m

$611

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 3/19

4:50 pm-2:40 pm

2 stops44h 50m

Santiago Arturo Merino Benitez

Thu 3/26

10:30 am-11:59 pm

1 stop14h 29m

$621

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 3/19

5:20 am-2:40 pm

3 stops32h 20m

Santiago Arturo Merino Benitez

Thu 3/26

9:05 pm-11:59 pm

2 stops27h 54m

$642

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 3/19

5:20 am-3:35 am

2 stops21h 15m

Santiago Arturo Merino Benitez

Thu 3/26

9:05 pm-11:59 pm

2 stops27h 54m

$676

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 3/19

5:20 am-2:40 pm

3 stops32h 20m

Santiago Arturo Merino Benitez

Thu 3/26

12:35 pm-10:37 pm

3 stops35h 02m

$683

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 4/26

10:10 pm-4:45 am

2 stops30h 35m

Santiago Arturo Merino Benitez

Sat 5/2

8:30 am-6:44 pm

2 stops34h 14m

$689

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sat 4/25

1:28 pm-3:55 am

2 stops38h 27m

Santiago Arturo Merino Benitez

Sat 5/2

8:30 am-6:44 pm

2 stops34h 14m

$694

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santiago from

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Santiago?

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time

16h 04m

Direct flights

None
The fastest flight from Detroit to Santiago takes 16h 04m
There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.
  • How far is Detroit to Santiago Arturo Merino Benitez by plane?

    The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 16h 04m.

  • When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santiago?

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $563Free CancellationRating
7.9
8,212 reviews
Search Delta flights
LATAM AirlinesPriceFrom $733Free CancellationRating
7.5
1,921 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Sat 3/21
Sat 3/28

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