Which layover airport offers the lowest fares from Detroit to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $863.

Which layover airport has the shortest connection time from Detroit to Santiago?

New York (JFK) has the shortest average layover time for this route: 2h 37m.

Which airport is the most popular layover for flights between Detroit and Santiago?

Dallas (DFW) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Detroit to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 14h 21m.

When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

As of April 2026, there is 1 operator available to choose from for flights from Detroit to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$329 Cheap Flights from Detroit to Santiago in 2026

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Find the cheapest flights from Detroit to Santiago

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:20 am - 3:55 am

DTW

SCL

22h 35m

2 stops

6:40 am - 9:05 pm

SCL

DTW

38h 25m

3 stops

$752Multiple Airlines

Sun, Apr 12 - Wed, Apr 15

6:50 am - 2:15 pm

DTW

SCL

31h 25m

3 stops

3:20 pm - 10:33 pm

SCL

DTW

31h 13m

2 stops

$771Multiple Airlines

Sun, Apr 26 - Sat, May 2

5:25 pm - 4:45 am

DTW

SCL

35h 20m

2 stops

6:40 am - 12:52 pm

SCL

DTW

30h 12m

2 stops

$773Multiple Airlines

Sun, Apr 26 - Sat, May 2

4:17 pm - 4:45 am

DTW

SCL

36h 28m

3 stops

3:20 pm - 10:52 pm

SCL

DTW

31h 32m

3 stops

$776Multiple Airlines

Sun, Apr 12 - Wed, Apr 15

8:30 pm - 5:30 am

DTW

SCL

33h 00m

3 stops

3:20 pm - 11:53 pm

SCL

DTW

32h 33m

2 stops

$788Multiple Airlines

Mon, Apr 27 - Mon, May 4

6:50 am - 2:15 pm

DTW

SCL

31h 25m

3 stops

12:30 am - 8:02 am

SCL

DTW

31h 32m

3 stops

$790Multiple Airlines

Sun, Apr 26 - Fri, May 1

5:25 pm - 2:15 pm

DTW

SCL

20h 50m

2 stops

6:40 am - 7:52 am

SCL

DTW

25h 12m

2 stops

$792Multiple Airlines

Mon, Apr 27 - Mon, May 11

5:25 pm - 2:15 pm

DTW

SCL

20h 50m

2 stops

3:20 pm - 11:53 pm

SCL

DTW

32h 33m

2 stops

$807Multiple Airlines

Mon, Apr 27 - Mon, May 4

8:30 pm - 1:30 pm

DTW

SCL

41h 00m

3 stops

6:40 am - 10:40 pm

SCL

DTW

40h 00m

3 stops

$826Multiple Airlines

Mon, Apr 27 - Mon, May 4

1:58 pm - 6:25 am

DTW

SCL

16h 27m

1 stop

11:17 am - 7:52 am

SCL

DTW

20h 35m

2 stops

$834Multiple Airlines

Mon, Apr 27 - Mon, May 11

United Airlines flights from Detroit to Santiago

Our best United Airlines deals on Detroit to Santiago flight tickets

United Airlines

Jul 22

DTW6:15 amDetroit Metropolitan Wayne County

22h 48m

2 stops

SCL5:03 amSantiago Arturo Merino Benitez

Aug 11

SCL2:27 amSantiago Arturo Merino Benitez

31h 05m

2 stops

DTW9:32 amDetroit Metropolitan Wayne County

$1,028

United Airlines

Jul 25

DTW10:55 amDetroit Metropolitan Wayne County

16h 05m

2 stops

SCL3:00 amSantiago Arturo Merino Benitez

Aug 9

SCL2:27 amSantiago Arturo Merino Benitez

19h 57m

2 stops

DTW10:24 pmDetroit Metropolitan Wayne County

$1,078

United Airlines

May 12

DTW11:40 amDetroit Metropolitan Wayne County

17h 30m

2 stops

SCL5:10 amSantiago Arturo Merino Benitez

May 19

SCL11:17 amSantiago Arturo Merino Benitez

33h 26m

2 stops

DTW8:43 pmDetroit Metropolitan Wayne County

$1,133

American Airlines flights from Detroit to Santiago

Our best American Airlines deals on Detroit to Santiago flight tickets

American Airlines

Jul 22

DTW6:00 amDetroit Metropolitan Wayne County

24h 50m

1 stop

SCL6:50 amSantiago Arturo Merino Benitez

Aug 12

SCL8:30 pmSantiago Arturo Merino Benitez

18h 47m

2 stops

DTW3:17 pmDetroit Metropolitan Wayne County

$1,042

American Airlines

Jul 25

DTW4:22 pmDetroit Metropolitan Wayne County

14h 28m

1 stop

SCL6:50 amSantiago Arturo Merino Benitez

Aug 10

SCL8:30 pmSantiago Arturo Merino Benitez

20h 03m

2 stops

DTW4:33 pmDetroit Metropolitan Wayne County

$1,080

American Airlines

Jul 25

DTW4:22 pmDetroit Metropolitan Wayne County

14h 28m

1 stop

SCL6:50 amSantiago Arturo Merino Benitez

Aug 10

SCL8:30 pmSantiago Arturo Merino Benitez

26h 57m

1 stop

DTW11:27 pmDetroit Metropolitan Wayne County

$1,088

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 4/12

5:20 am-3:55 am

2 stops22h 35m

Santiago Arturo Merino Benitez

Wed 4/15

6:40 am-9:05 pm

3 stops38h 25m

$752

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 4/26

6:50 am-2:15 pm

3 stops31h 25m

Santiago Arturo Merino Benitez

Sat 5/2

3:20 pm-10:33 pm

2 stops31h 13m

$771

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 4/26

5:25 pm-4:45 am

2 stops35h 20m

Santiago Arturo Merino Benitez

Sat 5/2

6:40 am-12:52 pm

2 stops30h 12m

$773

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 4/12

4:17 pm-4:45 am

3 stops36h 28m

Santiago Arturo Merino Benitez

Wed 4/15

3:20 pm-10:52 pm

3 stops31h 32m

$776

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 4/27

8:30 pm-5:30 am

3 stops33h 00m

Santiago Arturo Merino Benitez

Mon 5/4

3:20 pm-11:53 pm

2 stops32h 33m

$788

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Sun 4/26

6:50 am-2:15 pm

3 stops31h 25m

Santiago Arturo Merino Benitez

Fri 5/1

12:30 am-8:02 am

3 stops31h 32m

$790

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 4/27

5:25 pm-2:15 pm

2 stops20h 50m

Santiago Arturo Merino Benitez

Mon 5/11

6:40 am-7:52 am

2 stops25h 12m

$792

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 4/27

5:25 pm-2:15 pm

2 stops20h 50m

Santiago Arturo Merino Benitez

Mon 5/4

3:20 pm-11:53 pm

2 stops32h 33m

$807

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 4/27

8:30 pm-1:30 pm

3 stops41h 00m

Santiago Arturo Merino Benitez

Mon 5/4

6:40 am-10:40 pm

3 stops40h 00m

$826

Quickest round-trip

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 4/27

1:58 pm-6:25 am

1 stop16h 27m

Santiago Arturo Merino Benitez

Mon 5/11

11:17 am-7:52 am

2 stops20h 35m

$834

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Layovers

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time	12h 25m
Direct flights	None

The fastest flight from Detroit to Santiago takes 12h 25m

There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.

Search flight deals

Frequently asked questions about flying from Detroit to Santiago

How far is Detroit to Santiago Arturo Merino Benitez by plane?
The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 12h 25m.
When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?
Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.
How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?
As of April 2026, there is 1 operator available to choose from for flights from Detroit to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Detroit to Santiago?
momondo data reveals that the most frequently booked airline on the route from Detroit to Santiago is Delta, representing 54% of all bookings. The subsequent popular airline is LATAM Airlines at 46%.

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $563	Free Cancellation	Rating 7.9 8,368 reviews		Search Delta flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.