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Cheap flights from Detroit to Santiago from $270

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 1/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:15 am - 4:21 am
DTW
-
SCL
21h 06m
2 stops
Multiple Airlines Logo
12:35 pm - 12:09 am
SCL
-
DTW
37h 34m
3 stops
$559Multiple Airlines
mar., ene. 27 - mar., feb. 24
Multiple Airlines Logo
5:15 am - 4:21 am
DTW
-
SCL
21h 06m
2 stops
Multiple Airlines Logo
11:25 pm - 8:31 am
SCL
-
DTW
35h 06m
1 stop
$604Multiple Airlines
mar., ene. 27 - mar., feb. 24
Multiple Airlines Logo
5:15 am - 4:21 am
DTW
-
SCL
21h 06m
2 stops
Multiple Airlines Logo
9:05 pm - 7:52 pm
SCL
-
DTW
24h 47m
2 stops
$610Multiple Airlines
mar., ene. 27 - mar., feb. 24
Multiple Airlines Logo
3:14 pm - 4:21 am
DTW
-
SCL
35h 07m
2 stops
Multiple Airlines Logo
11:25 pm - 7:52 pm
SCL
-
DTW
22h 27m
1 stop
$620Multiple Airlines
lun., ene. 26 - mar., feb. 24
Multiple Airlines Logo
4:36 pm - 5:30 am
DTW
-
SCL
35h 54m
2 stops
Multiple Airlines Logo
7:15 am - 11:59 pm
SCL
-
DTW
17h 44m
2 stops
$650Multiple Airlines
dom., mar. 8 - mar., mar. 17
Multiple Airlines Logo
2:15 pm - 12:00 pm
DTW
-
SCL
44h 45m
3 stops
Multiple Airlines Logo
10:35 am - 11:59 pm
SCL
-
DTW
14h 24m
1 stop
$658Multiple Airlines
mar., mar. 10 - mié., mar. 18
Multiple Airlines Logo
8:52 pm - 5:30 am
DTW
-
SCL
31h 38m
2 stops
Multiple Airlines Logo
10:35 am - 11:59 pm
SCL
-
DTW
14h 24m
1 stop
$669Multiple Airlines
mar., mar. 10 - mié., mar. 18
Multiple Airlines Logo
10:16 am - 9:55 pm
DTW
-
SCL
33h 39m
3 stops
Multiple Airlines Logo
9:05 pm - 9:54 pm
SCL
-
DTW
26h 49m
3 stops
$676Multiple Airlines
mié., feb. 18 - mié., feb. 25
Multiple Airlines Logo
8:00 am - 5:30 am
DTW
-
SCL
20h 30m
2 stops
Multiple Airlines Logo
11:25 pm - 7:46 pm
SCL
-
DTW
21h 21m
1 stop
$679Multiple Airlines
mié., mar. 11 - mar., mar. 17
Multiple Airlines Logo
6:05 am - 5:30 am
DTW
-
SCL
22h 25m
2 stops
Multiple Airlines Logo
10:35 am - 11:59 pm
SCL
-
DTW
14h 24m
1 stop
$680Multiple Airlines
lun., mar. 9 - mié., mar. 18

Air Canada flights from Detroit to Santiago

Our best Air Canada deals on Detroit to Santiago flight tickets
Air Canada
Jan 27
DTW6:15 pmDetroit Metropolitan Wayne County
16h 00m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Feb 24
SCL8:55 pmSantiago Arturo Merino Benitez
22h 40m
1 stop
DTW5:35 pmDetroit Metropolitan Wayne County
$882
Air Canada
Jan 23
DTW6:15 pmDetroit Metropolitan Wayne County
16h 00m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Jan 25
SCL8:25 amSantiago Arturo Merino Benitez
59h 10m
2 stops
DTW5:35 pmDetroit Metropolitan Wayne County
$1,206
Air Canada
Jan 23
DTW6:15 pmDetroit Metropolitan Wayne County
16h 00m
1 stop
SCL12:15 pmSantiago Arturo Merino Benitez
Feb 7
SCL8:55 pmSantiago Arturo Merino Benitez
22h 40m
1 stop
DTW5:35 pmDetroit Metropolitan Wayne County
$5,207

LATAM Airlines flights from Detroit to Santiago

Our best LATAM Airlines deals on Detroit to Santiago flight tickets
LATAM Airlines
Jan 25
DTW12:21 pmDetroit Metropolitan Wayne County
24h 09m
3 stops
SCL2:30 pmSantiago Arturo Merino Benitez
Jan 27
SCL6:40 amSantiago Arturo Merino Benitez
20h 05m
2 stops
DTW12:45 amDetroit Metropolitan Wayne County
$1,955
LATAM Airlines
Jan 23
DTW12:21 pmDetroit Metropolitan Wayne County
24h 04m
3 stops
SCL2:25 pmSantiago Arturo Merino Benitez
Jan 25
SCL10:35 amSantiago Arturo Merino Benitez
16h 10m
2 stops
DTW12:45 amDetroit Metropolitan Wayne County
$2,075
LATAM Airlines
Jan 23
DTW12:21 pmDetroit Metropolitan Wayne County
24h 04m
3 stops
SCL2:25 pmSantiago Arturo Merino Benitez
Jan 25
SCL7:15 amSantiago Arturo Merino Benitez
19h 30m
3 stops
DTW12:45 amDetroit Metropolitan Wayne County
$2,402

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 21, 2026.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mar. 1/27

5:15 am-4:21 am

2 stops21h 06m

Santiago Arturo Merino Benitez

mar. 2/24

12:35 pm-12:09 am

3 stops37h 34m

$559

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mar. 1/27

5:15 am-4:21 am

2 stops21h 06m

Santiago Arturo Merino Benitez

mar. 2/24

11:25 pm-8:31 am

1 stop35h 06m

$604

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mar. 1/27

5:15 am-4:21 am

2 stops21h 06m

Santiago Arturo Merino Benitez

mar. 2/24

9:05 pm-7:52 pm

2 stops24h 47m

$610

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lun. 1/26

3:14 pm-4:21 am

2 stops35h 07m

Santiago Arturo Merino Benitez

mar. 2/24

11:25 pm-7:52 pm

1 stop22h 27m

$620

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

dom. 3/8

4:36 pm-5:30 am

2 stops35h 54m

Santiago Arturo Merino Benitez

mar. 3/17

7:15 am-11:59 pm

2 stops17h 44m

$650

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mar. 3/10

2:15 pm-12:00 pm

3 stops44h 45m

Santiago Arturo Merino Benitez

mié. 3/18

10:35 am-11:59 pm

1 stop14h 24m

$658

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mar. 3/10

8:52 pm-5:30 am

2 stops31h 38m

Santiago Arturo Merino Benitez

mié. 3/18

10:35 am-11:59 pm

1 stop14h 24m

$669

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mié. 2/18

10:16 am-9:55 pm

3 stops33h 39m

Santiago Arturo Merino Benitez

mié. 2/25

9:05 pm-9:54 pm

3 stops26h 49m

$676

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

mié. 3/11

8:00 am-5:30 am

2 stops20h 30m

Santiago Arturo Merino Benitez

mar. 3/17

11:25 pm-7:46 pm

1 stop21h 21m

$679

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

lun. 3/9

6:05 am-5:30 am

2 stops22h 25m

Santiago Arturo Merino Benitez

mié. 3/18

10:35 am-11:59 pm

1 stop14h 24m

$680

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Santiago?

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 3% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Fastest flight time

16h 00m

Direct flights

None
The fastest flight from Detroit to Santiago takes 16h 00m
There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.
Search flight deals

  • How far is Detroit to Santiago Arturo Merino Benitez by plane?

    The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 16h 00m.

  • When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santiago?

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $563Free CancellationRating
7.9
8,088 reviews
Search Delta flights
LATAM AirlinesPriceFrom $733Free CancellationRating
7.5
1,913 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

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Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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