Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Detroit to Santiago from $302

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Santiago departing on 10/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Detroit to Santiago

Cheap round-trip flights

Logo
6:52 am - 5:30 amDTW-SCL
21h 38m2 stops
Logo
1:35 am - 6:54 pmSCL-DTW
19h 19m2 stops
$557
Find Deal
Thu, Oct 30 - Wed, Nov 5
Logo
6:30 am - 12:20 pmDTW-SCL
28h 50m3 stops
Logo
9:15 pm - 8:14 pmSCL-DTW
23h 59m2 stops
$616
Find Deal
Fri, Sep 26 - Mon, Sep 29
Logo
6:30 am - 2:45 pmDTW-SCL
31h 15m2 stops
Logo
12:30 pm - 8:14 pmSCL-DTW
32h 44m2 stops
$617
Find Deal
Fri, Sep 26 - Mon, Sep 29
Logo
6:52 am - 5:30 amDTW-SCL
21h 38m2 stops
Logo
4:25 pm - 2:09 pmSCL-DTW
23h 44m2 stops
$623
Find Deal
Tue, Oct 28 - Tue, Nov 4
Logo
6:17 am - 2:45 pmDTW-SCL
31h 28m2 stops
Logo
10:50 am - 2:09 pmSCL-DTW
29h 19m1 stop
$629
Find Deal
Mon, Oct 20 - Fri, Nov 14
Logo
6:17 am - 12:20 pmDTW-SCL
29h 03m3 stops
Logo
10:50 am - 2:09 pmSCL-DTW
29h 19m1 stop
$630
Find Deal
Mon, Oct 20 - Fri, Nov 14
Logo
6:17 am - 12:20 pmDTW-SCL
29h 03m3 stops
Logo
10:50 am - 2:09 pmSCL-DTW
29h 19m1 stop
$631
Find Deal
Mon, Oct 20 - Fri, Nov 14
Logo
6:52 am - 5:30 amDTW-SCL
21h 38m2 stops
Logo
1:35 am - 11:30 pmSCL-DTW
23h 55m2 stops
$639
Find Deal
Tue, Oct 28 - Mon, Nov 3
Logo
6:17 am - 2:45 pmDTW-SCL
31h 28m2 stops
Logo
11:25 pm - 2:09 pmSCL-DTW
16h 44m1 stop
$640
Find Deal
Mon, Oct 20 - Wed, Nov 12
Logo
6:17 am - 12:20 pmDTW-SCL
29h 03m3 stops
Logo
11:25 pm - 2:09 pmSCL-DTW
16h 44m1 stop
$641
Find Deal
Mon, Oct 20 - Wed, Nov 12

American Airlines flights from Detroit to Santiago

Our best American Airlines deals on Detroit to Santiago flight tickets
American Airlines
Sep 17
DTW11:55 amDetroit Metropolitan Wayne County
19h 00m
2 stops
SCL7:55 amSantiago Arturo Merino Benitez
Sep 22
SCL9:55 pmSantiago Arturo Merino Benitez
20h 06m
2 stops
DTW5:01 pmDetroit Metropolitan Wayne County
$1,138
Find similar
American Airlines
Sep 17
DTW2:28 pmDetroit Metropolitan Wayne County
16h 27m
2 stops
SCL7:55 amSantiago Arturo Merino Benitez
Sep 22
SCL9:55 pmSantiago Arturo Merino Benitez
26h 03m
1 stop
DTW10:58 pmDetroit Metropolitan Wayne County
$1,150
Find similar

LATAM Airlines flights from Detroit to Santiago

Our best LATAM Airlines deals on Detroit to Santiago flight tickets
LATAM Airlines
Sep 17
DTW4:23 pmDetroit Metropolitan Wayne County
13h 37m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Sep 22
SCL9:40 pmSantiago Arturo Merino Benitez
22h 04m
1 stop
DTW6:44 pmDetroit Metropolitan Wayne County
$1,937
Find similar
LATAM Airlines
Sep 17
DTW7:02 amDetroit Metropolitan Wayne County
22h 58m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Sep 21
SCL12:10 amSantiago Arturo Merino Benitez
17h 47m
2 stops
DTW4:57 pmDetroit Metropolitan Wayne County
$1,950
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Detroit to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Thu 10/30

6:52 am-5:30 am

2 stops21h 38m

Santiago Arturo Merino Benitez

Wed 11/5

1:35 am-6:54 pm

2 stops19h 19m

$557

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 9/26

6:30 am-12:20 pm

3 stops28h 50m

Santiago Arturo Merino Benitez

Mon 9/29

9:15 pm-8:14 pm

2 stops23h 59m

$616

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Fri 9/26

6:30 am-2:45 pm

2 stops31h 15m

Santiago Arturo Merino Benitez

Mon 9/29

12:30 pm-8:14 pm

2 stops32h 44m

$617

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 10/28

6:52 am-5:30 am

2 stops21h 38m

Santiago Arturo Merino Benitez

Tue 11/4

4:25 pm-2:09 pm

2 stops23h 44m

$623

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 10/20

6:17 am-2:45 pm

2 stops31h 28m

Santiago Arturo Merino Benitez

Fri 11/14

10:50 am-2:09 pm

1 stop29h 19m

$629

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 10/20

6:17 am-12:20 pm

3 stops29h 03m

Santiago Arturo Merino Benitez

Fri 11/14

10:50 am-2:09 pm

1 stop29h 19m

$630

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 10/20

6:17 am-12:20 pm

3 stops29h 03m

Santiago Arturo Merino Benitez

Fri 11/14

10:50 am-2:09 pm

1 stop29h 19m

$631

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Tue 10/28

6:52 am-5:30 am

2 stops21h 38m

Santiago Arturo Merino Benitez

Mon 11/3

1:35 am-11:30 pm

2 stops23h 55m

$639

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 10/20

6:17 am-2:45 pm

2 stops31h 28m

Santiago Arturo Merino Benitez

Wed 11/12

11:25 pm-2:09 pm

1 stop16h 44m

$640

DetroitSantiago

DTW - SCL

DTWSCL

Detroit Metropolitan Wayne County

Mon 10/20

6:17 am-12:20 pm

3 stops29h 03m

Santiago Arturo Merino Benitez

Wed 11/12

11:25 pm-2:09 pm

1 stop16h 44m

$641

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to Santiago from

How to get the cheapest flight ticket from Detroit to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Saturday when prices can be found for as low as $932. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $1,272.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Detroit to Santiago when you can find flight prices for as low as $937. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,126 per ticket.

Can stopping save me money on Detroit to Santiago flights?

You could potentially save up to 10% on your flight if you consider stops on a Detroit to Santiago flight.

When to book flights from Detroit to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Santiago (DTT to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Santiago

Direct flights

None
There are no direct flights from Detroit to Santiago. There are no popular flight routes from Detroit to Santiago.
Search flight deals

  • How far is Detroit to Santiago Arturo Merino Benitez by plane?

    The distance between Detroit and Santiago Arturo Merino Benitez is about 5291.2 mi. In terms of flight time, this usually takes a little over 16h 00m.

  • When did momondo last update prices for flights from Detroit to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Detroit to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Detroit to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Detroit to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Santiago?

Best airlines flying from Detroit to Santiago

Compare and see reviews for airlines that fly from Detroit to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Air CanadaPriceFrom $684Free CancellationRating
7.1
10,000 reviews
Search Air Canada flights
LATAM AirlinesPriceFrom $733Free CancellationRating
7.5
1,847 reviews
Search LATAM Airlines flights
DeltaPriceFrom $768Free CancellationRating
7.9
7,954 reviews
Search Delta flights
American AirlinesPriceFrom $822Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santiago?

It is quick and easy to find Detroit to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Detroit to Santiago with flexible booking policies on momondo?

Flights from Detroit to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Detroit. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Detroit to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Detroit to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 10/15
Wed 10/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chile