Cheap flights from Detroit to Panama City from $227
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 12/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Use the filters below to find and compare flights from Detroit to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Mon 3/1
10:37 am-8:02 pm
1 stop9h 25m
Panama City Tocumen Intl
Wed 3/31
9:45 am-11:04 pm
1 stop12h 19m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Mon 3/1
10:37 am-8:02 pm
1 stop9h 25m
Panama City Tocumen Intl
Wed 3/31
9:45 am-11:04 pm
1 stop12h 19m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Wed 1/20
7:04 pm-3:55 pm
2 stops20h 51m
Panama City Tocumen Intl
Wed 1/27
2:26 pm-11:43 pm
1 stop9h 17m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Wed 1/20
7:04 pm-3:55 pm
2 stops20h 51m
Panama City Tocumen Intl
Wed 1/27
2:26 pm-9:37 am
2 stops19h 11m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Tue 12/15
4:08 pm-5:12 pm
2 stops25h 04m
Panama City Tocumen Intl
Mon 12/21
10:00 am-11:59 pm
1 stop13h 59m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Tue 2/2
5:00 am-1:26 pm
1 stop8h 26m
Panama City Tocumen Intl
Fri 2/12
2:47 pm-11:57 pm
1 stop9h 10m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Thu 12/3
8:35 am-7:38 pm
1 stop11h 03m
Panama City Tocumen Intl
Thu 12/17
4:41 pm-9:28 am
2 stops16h 47m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Mon 2/1
5:00 am-3:55 pm
1 stop10h 55m
Panama City Tocumen Intl
Fri 2/12
2:47 pm-11:57 pm
1 stop9h 10m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Sun 2/7
7:45 pm-1:55 pm
1 stop18h 10m
Panama City Tocumen Intl
Thu 2/25
3:20 pm-9:28 am
1 stop18h 08m
DetroitPanama City
DTW Detroit Metropolitan Wayne County - PTY Panama City Tocumen Intl
DTWPTY
Detroit Metropolitan Wayne County
Fri 2/5
7:45 pm-12:15 pm
1 stop16h 30m
Panama City Tocumen Intl
Thu 2/25
3:20 pm-9:28 am
1 stop18h 08m
See travel insights to Panama City from
How to get the cheapest flight ticket from Detroit to Panama City
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest airline that flies from Detroit to Panama City Tocumen Intl?
United Airlines is the most popular carrier operating from Detroit to Panama City Tocumen Intl
What airlines fly to Panama City?
Delta, American Airlines and Copa Airlines are the top three most popular airlines that fly to Panama City from Detroit according to our data. Delta is the first choice among our users, with 31% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.
Which airport is the most popular layover for flights between Detroit and Panama City?
Miami (MIA) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.
Which layover airport offers the lowest fares from Detroit to Panama City?
Flights via Miami (MIA) offer the lowest average round-trip price of $893.
Which layover airport has the shortest travel time from Detroit to Panama City?
Flights connecting via Miami (MIA) have the shortest average one-way travel time: 7h 22m.
Which layover airport has the shortest connection time from Detroit to Panama City?
Miami (MIA) has the shortest average layover time for this route: 2h 06m.
When to book flights from Detroit to Panama City
Cheap Detroit to Panama City (DTT to PTY) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City
Frequently asked questions about flying from Detroit to Panama City
How far is Detroit to Panama City Tocumen Intl by plane?
Detroit and Panama City Tocumen Intl are 2312.9 mi apart from one another. Flights usually cover this in 8h 57m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Detroit to Panama City Tocumen Intl Airport?
Prices for flights from Detroit to Panama City Tocumen Intl Airport are updated daily.
How many operators does momondo search for flights from Detroit to Panama City Tocumen Intl Airport?
There are 4 operators available for flights from Detroit to Panama City Tocumen Intl Airport as of October 2026.
How old do you have to be to fly from Detroit to Panama City Tocumen Intl Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
Best airlines flying from Detroit to Panama City
Compare and see reviews for airlines that fly from Detroit to Panama City with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $568 | Free Cancellation | Rating 7.4 10,331 reviews | |||
| PriceFrom $611 | Free Cancellation | Rating 7.6 1,550 reviews | |||
| PriceFrom $655 | Free Cancellation | Rating 7.8 8,651 reviews | |||
| PriceFrom $671 | Free Cancellation | Rating 7.0 12,149 reviews |
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Detroit to Panama City?
To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.
Can I find flights from Detroit to Panama City with flexible booking policies on momondo?
Yes. momondo allows you to filter the results for Detroit to Panama City flights to just show those with flexible booking policies.
How can momondo help me find flights from Detroit to Panama City?
momondo helps you find the best flight between Detroit and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.
I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?
If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.