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Cheap flights from Detroit to Panama City from $202

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 3/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:16 am - 1:00 am
DTW
-
PTY
14h 44m2 stops
Multiple Airlines Logo
2:55 am - 7:57 pm
PTY
-
DTW
17h 02m2 stops
$447Multiple Airlines
Thu, Feb 19 - Tue, Feb 24
Multiple Airlines Logo
10:16 am - 1:00 am
DTW
-
PTY
14h 44m2 stops
Multiple Airlines Logo
2:55 am - 7:57 pm
PTY
-
DTW
17h 02m2 stops
$456Multiple Airlines
Tue, Feb 17 - Mon, Feb 23
Multiple Airlines Logo
5:45 am - 12:40 am
DTW
-
PTY
18h 55m2 stops
Multiple Airlines Logo
2:55 am - 11:59 pm
PTY
-
DTW
21h 04m2 stops
$460Multiple Airlines
Wed, Feb 18 - Tue, Feb 24
Multiple Airlines Logo
6:35 am - 12:40 am
DTW
-
PTY
18h 05m2 stops
Multiple Airlines Logo
2:55 am - 7:07 pm
PTY
-
DTW
16h 12m2 stops
$467Multiple Airlines
Wed, Jan 28 - Tue, Feb 10
Multiple Airlines Logo
5:45 am - 12:40 am
DTW
-
PTY
18h 55m2 stops
Multiple Airlines Logo
2:55 am - 11:59 pm
PTY
-
DTW
21h 04m2 stops
$474Multiple Airlines
Wed, Feb 18 - Thu, Feb 26
Multiple Airlines Logo
12:33 pm - 8:06 am
DTW
-
PTY
19h 33m1 stop
Multiple Airlines Logo
2:55 am - 6:21 pm
PTY
-
DTW
15h 26m2 stops
$499Multiple Airlines
Wed, Feb 18 - Tue, Feb 24
Multiple Airlines Logo
5:08 pm - 8:34 pm
DTW
-
PTY
27h 26m1 stop
Multiple Airlines Logo
5:50 pm - 9:46 am
PTY
-
DTW
39h 56m2 stops
$505Multiple Airlines
Sat, Feb 21 - Sat, Feb 28
Multiple Airlines Logo
12:33 pm - 8:37 pm
DTW
-
PTY
8h 04m1 stop
Multiple Airlines Logo
9:33 pm - 8:31 am
PTY
-
DTW
10h 58m1 stop
$516Multiple Airlines
Thu, Feb 19 - Wed, Feb 25
Multiple Airlines Logo
6:35 am - 1:00 am
DTW
-
PTY
18h 25m2 stops
Multiple Airlines Logo
5:50 pm - 9:11 am
PTY
-
DTW
15h 21m2 stops
$518Multiple Airlines
Tue, Feb 10 - Tue, Feb 17
Multiple Airlines Logo
11:00 am - 8:34 pm
DTW
-
PTY
9h 34m1 stop
Multiple Airlines Logo
5:50 pm - 10:05 am
PTY
-
DTW
40h 15m2 stops
$519Multiple Airlines
Thu, Feb 5 - Sun, Feb 8

Delta flights from Detroit to Panama City

Our best Delta deals on Detroit to Panama City flight tickets
Delta
May 6
DTW5:20 amDetroit Metropolitan Wayne County
8h 35m
1 stop
PTY12:55 pmPanama City Tocumen Intl
May 13
PTY2:20 pmPanama City Tocumen Intl
16h 35m
1 stop
DTW7:55 amDetroit Metropolitan Wayne County
$609
Find similar
Delta
Jan 7
DTW6:15 amDetroit Metropolitan Wayne County
7h 40m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 12
PTY3:20 pmPanama City Tocumen Intl
8h 22m
1 stop
DTW11:42 pmDetroit Metropolitan Wayne County
$1,179
Find similar
Delta
Jan 7
DTW6:15 amDetroit Metropolitan Wayne County
7h 40m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 12
PTY3:20 pmPanama City Tocumen Intl
8h 22m
1 stop
DTW11:42 pmDetroit Metropolitan Wayne County
$1,194
Find similar

Avianca flights from Detroit to Panama City

Our best Avianca deals on Detroit to Panama City flight tickets
Avianca
Jan 12
DTW7:45 pmDetroit Metropolitan Wayne County
14h 45m
2 stops
PTY10:30 amPanama City Tocumen Intl
Mar 11
PTY3:50 pmPanama City Tocumen Intl
17h 14m
2 stops
DTW10:04 amDetroit Metropolitan Wayne County
$743
Find similar
Avianca
Jan 12
DTW7:45 pmDetroit Metropolitan Wayne County
19h 10m
3 stops
PTY2:55 pmPanama City Tocumen Intl
Mar 11
PTY3:50 pmPanama City Tocumen Intl
17h 14m
2 stops
DTW10:04 amDetroit Metropolitan Wayne County
$785
Find similar
Avianca
Jan 11
DTW7:45 pmDetroit Metropolitan Wayne County
14h 45m
2 stops
PTY10:30 amPanama City Tocumen Intl
Jan 16
PTY7:50 pmPanama City Tocumen Intl
14h 17m
2 stops
DTW10:07 amDetroit Metropolitan Wayne County
$920
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/19

10:16 am-1:00 am

2 stops14h 44m

Panama City Tocumen Intl

Tue 2/24

2:55 am-7:57 pm

2 stops17h 02m

$447

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 2/17

10:16 am-1:00 am

2 stops14h 44m

Panama City Tocumen Intl

Mon 2/23

2:55 am-7:57 pm

2 stops17h 02m

$456

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 2/18

5:45 am-12:40 am

2 stops18h 55m

Panama City Tocumen Intl

Tue 2/24

2:55 am-11:59 pm

2 stops21h 04m

$460

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 1/28

6:35 am-12:40 am

2 stops18h 05m

Panama City Tocumen Intl

Tue 2/10

2:55 am-7:07 pm

2 stops16h 12m

$467

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 2/18

5:45 am-12:40 am

2 stops18h 55m

Panama City Tocumen Intl

Thu 2/26

2:55 am-11:59 pm

2 stops21h 04m

$474

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 2/18

12:33 pm-8:06 am

1 stop19h 33m

Panama City Tocumen Intl

Tue 2/24

2:55 am-6:21 pm

2 stops15h 26m

$499

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 2/21

5:08 pm-8:34 pm

1 stop27h 26m

Panama City Tocumen Intl

Sat 2/28

5:50 pm-9:46 am

2 stops39h 56m

$505

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/19

12:33 pm-8:37 pm

1 stop8h 04m

Panama City Tocumen Intl

Wed 2/25

9:33 pm-8:31 am

1 stop10h 58m

$516

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 2/10

6:35 am-1:00 am

2 stops18h 25m

Panama City Tocumen Intl

Tue 2/17

5:50 pm-9:11 am

2 stops15h 21m

$518

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/5

11:00 am-8:34 pm

1 stop9h 34m

Panama City Tocumen Intl

Sun 2/8

5:50 pm-10:05 am

2 stops40h 15m

$519

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Panama City?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama City from Detroit according to our data. American Airlines is the first choice among our users, with 42% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

When to book flights from Detroit to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City (DTT to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City

Fastest flight time

8h 31m

Direct flights

None
The fastest flight from Detroit to Panama City takes 8h 31m
There are no direct flights from Detroit to Panama City. There are no popular flight routes from Detroit to Panama City.
Search flight deals

  • How far is Detroit to Panama City Tocumen Intl by plane?

    Detroit and Panama City Tocumen Intl are 2312.9 mi apart from one another. Flights usually cover this in 8h 31m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit to Panama City Tocumen Intl Airport?

    Prices for flights from Detroit to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Detroit to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Detroit to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Panama City?

Best airlines flying from Detroit to Panama City

Compare and see reviews for airlines that fly from Detroit to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $578Free CancellationRating
7.2
11,074 reviews
Search American Airlines flights
United AirlinesPriceFrom $608Free CancellationRating
7.4
9,124 reviews
Search United Airlines flights
DeltaPriceFrom $608Free CancellationRating
7.9
8,013 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Panama City?

momondo helps you find the best flight between Detroit and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.

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