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Cheap flights from Detroit to Panama City from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 9/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
Logo
3:20 am - 11:43 pmPTY-DTW
19h 23m2 stops
$416
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Thu, Sep 11 - Wed, Sep 17
Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
Logo
3:19 am - 11:29 pmPTY-DTW
19h 10m2 stops
$427
Find Deal
Sun, Oct 19 - Sun, Oct 26
Logo
9:19 am - 9:10 pmDTW-PTY
12h 51m2 stops
Logo
3:25 am - 11:43 pmPTY-DTW
19h 18m2 stops
$436
Find Deal
Sat, Sep 6 - Fri, Sep 12
Logo
9:19 am - 9:10 pmDTW-PTY
12h 51m2 stops
Logo
3:20 am - 11:43 pmPTY-DTW
19h 23m2 stops
$437
Find Deal
Sat, Sep 6 - Sun, Sep 7
Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
Logo
3:20 am - 11:43 pmPTY-DTW
19h 23m2 stops
$438
Find Deal
Wed, Sep 17 - Tue, Sep 23
Logo
6:28 am - 9:10 pmDTW-PTY
15h 42m2 stops
Logo
3:20 am - 11:40 pmPTY-DTW
19h 20m2 stops
$439
Find Deal
Wed, Aug 27 - Tue, Sep 2
Logo
6:05 am - 9:10 pmDTW-PTY
16h 05m2 stops
Logo
10:05 pm - 8:00 pmPTY-DTW
20h 55m2 stops
$440
Find Deal
Thu, Sep 11 - Thu, Sep 18
Logo
6:15 am - 9:10 pmDTW-PTY
15h 55m2 stops
Logo
3:25 am - 8:00 pmPTY-DTW
15h 35m2 stops
$441
Find Deal
Thu, Aug 21 - Mon, Sep 15
Delta Logo
9:15 pm - 12:56 pmDTW-PTY
16h 41m1 stop
Delta Logo
2:21 pm - 9:25 amPTY-DTW
18h 04m1 stop
$491Delta
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Sun, Oct 19 - Wed, Oct 29
United Airlines Logo
7:00 am - 6:37 pmDTW-PTY
12h 37m2 stops
United Airlines Logo
3:41 pm - 9:45 amPTY-DTW
17h 04m2 stops
$496United Airlines
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Tue, Oct 21 - Tue, Oct 28

United Airlines flights from Detroit to Panama City

Our best United Airlines deals on Detroit to Panama City flight tickets
United Airlines
Oct 21
DTW7:00 amDetroit Metropolitan Wayne County
12h 37m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Oct 28
PTY3:41 pmPanama City Tocumen Intl
17h 04m
2 stops
DTW9:45 amDetroit Metropolitan Wayne County
$496
Find similar
United Airlines
Aug 12
DTW8:20 amDetroit Metropolitan Wayne County
8h 52m
1 stop
PTY4:12 pmPanama City Tocumen Intl
Aug 20
PTY10:55 pmPanama City Tocumen Intl
13h 19m
2 stops
DTW1:14 pmDetroit Metropolitan Wayne County
$757
Find similar
United Airlines
Aug 6
DTW7:00 amDetroit Metropolitan Wayne County
7h 50m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Aug 26
PTY10:00 amPanama City Tocumen Intl
12h 56m
1 stop
DTW11:56 pmDetroit Metropolitan Wayne County
$823
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momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/11

6:41 am-9:10 pm

2 stops15h 29m

Panama City Tocumen Intl

Wed 9/17

3:20 am-11:43 pm

2 stops19h 23m

$416

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 10/19

6:41 am-9:10 pm

2 stops15h 29m

Panama City Tocumen Intl

Sun 10/26

3:19 am-11:29 pm

2 stops19h 10m

$427

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 9/6

9:19 am-9:10 pm

2 stops12h 51m

Panama City Tocumen Intl

Fri 9/12

3:25 am-11:43 pm

2 stops19h 18m

$436

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 9/6

9:19 am-9:10 pm

2 stops12h 51m

Panama City Tocumen Intl

Sun 9/7

3:20 am-11:43 pm

2 stops19h 23m

$437

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/17

6:41 am-9:10 pm

2 stops15h 29m

Panama City Tocumen Intl

Tue 9/23

3:20 am-11:43 pm

2 stops19h 23m

$438

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 8/27

6:28 am-9:10 pm

2 stops15h 42m

Panama City Tocumen Intl

Tue 9/2

3:20 am-11:40 pm

2 stops19h 20m

$439

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/11

6:05 am-9:10 pm

2 stops16h 05m

Panama City Tocumen Intl

Thu 9/18

10:05 pm-8:00 pm

2 stops20h 55m

$440

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 8/21

6:15 am-9:10 pm

2 stops15h 55m

Panama City Tocumen Intl

Mon 9/15

3:25 am-8:00 pm

2 stops15h 35m

$441

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 10/19

9:15 pm-12:56 pm

1 stop16h 41m

Panama City Tocumen Intl

Wed 10/29

2:21 pm-9:25 am

1 stop18h 04m

$491

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 10/21

7:00 am-6:37 pm

2 stops12h 37m

Panama City Tocumen Intl

Tue 10/28

3:41 pm-9:45 am

2 stops17h 04m

$496

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Detroit to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $637. If you’re not able to fly to Panama City in August, then April is your next best option. Flight prices from Detroit to Panama City during April average around $648.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $745. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $861. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Detroit to Panama City during this time can be as low as $786. Try not to purchase tickets in the afternoon because they tend to be around $923. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Detroit when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $860 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Detroit for as low as $622 on momondo.

When to book flights from Detroit to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City (DTT to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City

Best Price Found

$178

Fastest flight time

8h 15m

Direct flights

None

Airports in Panama City

1 airport
The best one-way flight to Panama City from Detroit in the past 72 hours is $178. The best round-trip flight deal from Detroit to Panama City found on momondo in the last 72 hours is $416.
The fastest flight from Detroit to Panama City takes 8h 15m
There are no direct flights from Detroit to Panama City. Popular non-direct route for this connection is Detroit Metropolitan Wayne County Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
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  • How far is Detroit to Panama City Tocumen Intl by plane?

    Detroit and Panama City Tocumen Intl are 2312.9 mi apart from one another. Flights usually cover this in 9h 00m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit to Panama City Tocumen Intl Airport?

    Prices for flights from Detroit to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Detroit to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Detroit to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Detroit to Panama City?

Best airlines flying from Detroit to Panama City

Compare and see reviews for airlines that fly from Detroit to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $608Free CancellationRating
7.4
8,896 reviews
Search United Airlines flights
DeltaPriceFrom $608Free CancellationRating
8.0
7,980 reviews
Search Delta flights
American AirlinesPriceFrom $628Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Panama City?

momondo helps you find the best flight between Detroit and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.

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