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Cheap flights from Detroit to Panama City from $290

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$609Multiple Airlines
Tue, Sep 15 - Tue, Sep 29
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
11:25 am - 4:32 pm
PTY
-
DTW
28h 07m
3 stops
$642Multiple Airlines
Wed, Sep 16 - Wed, Sep 30
Multiple Airlines Logo
6:00 am - 10:30 am
DTW
-
PTY
29h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 11:58 pm
PTY
-
DTW
31h 08m
2 stops
$644Multiple Airlines
Sun, Aug 16 - Thu, Aug 20
Multiple Airlines Logo
6:00 am - 10:30 am
DTW
-
PTY
29h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 11:58 pm
PTY
-
DTW
31h 08m
2 stops
$655Multiple Airlines
Fri, Aug 21 - Fri, Aug 28
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$665Multiple Airlines
Wed, Sep 16 - Wed, Sep 23
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$666Multiple Airlines
Fri, Oct 9 - Sun, Oct 18
Multiple Airlines Logo
6:00 am - 10:30 am
DTW
-
PTY
29h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$669Multiple Airlines
Fri, Oct 9 - Sun, Oct 18
Multiple Airlines Logo
9:12 am - 8:19 pm
DTW
-
PTY
12h 07m
1 stop
Multiple Airlines Logo
10:10 am - 12:55 pm
PTY
-
DTW
25h 45m
2 stops
$690Multiple Airlines
Thu, Jul 16 - Thu, Jul 30
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
11:25 am - 4:32 pm
PTY
-
DTW
28h 07m
3 stops
$699Multiple Airlines
Wed, Sep 16 - Wed, Sep 23
Multiple Airlines Logo
6:00 am - 10:30 am
DTW
-
PTY
29h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 11:58 pm
PTY
-
DTW
31h 08m
2 stops
$700Multiple Airlines
Tue, Sep 1 - Sat, Sep 5

United Airlines flights from Detroit to Panama City

Our best United Airlines deals on Detroit to Panama City flight tickets
United Airlines
Sep 16
DTW7:00 amDetroit Metropolitan Wayne County
13h 31m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Sep 23
PTY9:45 amPanama City Tocumen Intl
24h 39m
2 stops
DTW11:24 amDetroit Metropolitan Wayne County
$757
United Airlines
Oct 9
DTW7:10 pmDetroit Metropolitan Wayne County
25h 21m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Oct 18
PTY3:30 pmPanama City Tocumen Intl
17h 04m
2 stops
DTW9:34 amDetroit Metropolitan Wayne County
$820
United Airlines
Jul 23
DTW5:30 amDetroit Metropolitan Wayne County
11h 42m
2 stops
PTY4:12 pmPanama City Tocumen Intl
Jul 31
PTY10:00 amPanama City Tocumen Intl
12h 44m
1 stop
DTW11:44 pmDetroit Metropolitan Wayne County
$843

Delta flights from Detroit to Panama City

Our best Delta deals on Detroit to Panama City flight tickets
Delta
Sep 16
DTW6:20 amDetroit Metropolitan Wayne County
7h 36m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Sep 30
PTY2:21 pmPanama City Tocumen Intl
8h 21m
1 stop
DTW11:42 pmDetroit Metropolitan Wayne County
$733
Delta
Sep 15
DTW6:20 amDetroit Metropolitan Wayne County
7h 36m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Sep 29
PTY2:21 pmPanama City Tocumen Intl
8h 21m
1 stop
DTW11:42 pmDetroit Metropolitan Wayne County
$753
Delta
Oct 9
DTW5:20 amDetroit Metropolitan Wayne County
8h 36m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 18
PTY2:21 pmPanama City Tocumen Intl
9h 23m
1 stop
DTW12:44 amDetroit Metropolitan Wayne County
$786

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 27, 2026.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/15

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Tue 9/29

3:50 pm-4:32 pm

2 stops23h 42m

$609

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Wed 9/30

11:25 am-4:32 pm

3 stops28h 07m

$642

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 8/16

6:00 am-10:30 am

2 stops29h 30m

Panama City Tocumen Intl

Thu 8/20

3:50 pm-11:58 pm

2 stops31h 08m

$644

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 8/21

6:00 am-10:30 am

2 stops29h 30m

Panama City Tocumen Intl

Fri 8/28

3:50 pm-11:58 pm

2 stops31h 08m

$655

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Wed 9/23

3:50 pm-4:32 pm

2 stops23h 42m

$665

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 10/9

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Sun 10/18

3:50 pm-4:32 pm

2 stops23h 42m

$666

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 10/9

6:00 am-10:30 am

2 stops29h 30m

Panama City Tocumen Intl

Sun 10/18

3:50 pm-4:32 pm

2 stops23h 42m

$669
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 7/16

9:12 am-8:19 pm

1 stop12h 07m

Panama City Tocumen Intl

Thu 7/30

10:10 am-12:55 pm

2 stops25h 45m

$690

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Wed 9/23

11:25 am-4:32 pm

3 stops28h 07m

$699

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/1

6:00 am-10:30 am

2 stops29h 30m

Panama City Tocumen Intl

Sat 9/5

3:50 pm-11:58 pm

2 stops31h 08m

$700

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Panama City?

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from Detroit to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $514. If you’re not able to fly to Panama City in March, then October is your next best option. Flight prices from Detroit to Panama City during October average around $562.

When to book flights from Detroit to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City (DTT to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City

Fastest flight time

8h 59m

Direct flights

None
The fastest flight from Detroit to Panama City takes 8h 59m
There are no direct flights from Detroit to Panama City. There are no popular flight routes from Detroit to Panama City.
Search flight deals

Frequently asked questions about flying from Detroit to Panama City

  • How far is Detroit to Panama City Tocumen Intl by plane?

    Detroit and Panama City Tocumen Intl are 2312.9 mi apart from one another. Flights usually cover this in 8h 59m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit to Panama City Tocumen Intl Airport?

    Prices for flights from Detroit to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Detroit to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Detroit to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to Panama City

Compare and see reviews for airlines that fly from Detroit to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $611Free CancellationRating
7.6
1,574 reviews
Search Copa Airlines flights
DeltaPriceFrom $668Free CancellationRating
7.9
8,423 reviews
Search Delta flights
American AirlinesPriceFrom $673Free CancellationRating
7.1
11,640 reviews
Search American Airlines flights
United AirlinesPriceFrom $708Free CancellationRating
7.4
9,751 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Panama City?

momondo helps you find the best flight between Detroit and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.

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