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Cheap flights from Detroit to Panama City from $260

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Panama City departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:50 am - 5:00 pm
DTW
-
PTY
35h 10m
3 stops
Multiple Airlines Logo
4:25 am - 7:52 am
PTY
-
DTW
26h 27m
3 stops
$559Multiple Airlines
Mon, Apr 27 - Tue, May 5
Multiple Airlines Logo
6:50 am - 8:37 pm
DTW
-
PTY
14h 47m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$562Multiple Airlines
Tue, Jun 2 - Tue, Jun 16
Multiple Airlines Logo
6:50 am - 8:37 pm
DTW
-
PTY
14h 47m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$574Multiple Airlines
Tue, Jun 2 - Wed, Jun 17
Multiple Airlines Logo
12:55 pm - 8:06 am
DTW
-
PTY
20h 11m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$575Multiple Airlines
Mon, Jun 1 - Tue, Jun 16
Multiple Airlines Logo
2:40 pm - 7:20 pm
DTW
-
PTY
29h 40m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$576Multiple Airlines
Sat, May 30 - Tue, Jun 16
Multiple Airlines Logo
2:54 pm - 8:06 am
DTW
-
PTY
18h 12m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$578Multiple Airlines
Sat, Jun 13 - Tue, Jun 16
Multiple Airlines Logo
12:55 pm - 8:06 am
DTW
-
PTY
20h 11m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$587Multiple Airlines
Mon, Jun 1 - Wed, Jun 17
Multiple Airlines Logo
6:20 am - 7:20 pm
DTW
-
PTY
14h 00m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$588Multiple Airlines
Wed, Jun 3 - Wed, Jun 17
Multiple Airlines Logo
6:50 am - 12:35 am
DTW
-
PTY
42h 45m
3 stops
Multiple Airlines Logo
3:10 pm - 11:53 pm
PTY
-
DTW
31h 43m
2 stops
$591Multiple Airlines
Mon, Apr 27 - Tue, May 5
Multiple Airlines Logo
6:50 am - 7:20 pm
DTW
-
PTY
13h 30m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$605Multiple Airlines
Sun, May 31 - Tue, Jun 16

United Airlines flights from Detroit to Panama City

Our best United Airlines deals on Detroit to Panama City flight tickets
United Airlines
Apr 20
DTW9:00 amDetroit Metropolitan Wayne County
8h 12m
1 stop
PTY4:12 pmPanama City Tocumen Intl
May 4
PTY7:55 amPanama City Tocumen Intl
14h 52m
1 stop
DTW11:47 pmDetroit Metropolitan Wayne County
$945
United Airlines
Apr 20
DTW6:00 amDetroit Metropolitan Wayne County
11h 12m
2 stops
PTY4:12 pmPanama City Tocumen Intl
May 4
PTY3:30 pmPanama City Tocumen Intl
15h 58m
2 stops
DTW8:28 amDetroit Metropolitan Wayne County
$949

American Airlines flights from Detroit to Panama City

Our best American Airlines deals on Detroit to Panama City flight tickets
American Airlines
Apr 27
DTW5:05 pmDetroit Metropolitan Wayne County
20h 41m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 5
PTY1:49 pmPanama City Tocumen Intl
9h 07m
1 stop
DTW11:56 pmDetroit Metropolitan Wayne County
$892
American Airlines
Apr 20
DTW7:49 pmDetroit Metropolitan Wayne County
17h 57m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 4
PTY1:49 pmPanama City Tocumen Intl
9h 07m
1 stop
DTW11:56 pmDetroit Metropolitan Wayne County
$974

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 13, 2026.
Use the filters below to find and compare flights from Detroit to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

6:50 am-5:00 pm

3 stops35h 10m

Panama City Tocumen Intl

Tue 5/5

4:25 am-7:52 am

3 stops26h 27m

$559

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/2

6:50 am-8:37 pm

2 stops14h 47m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$562

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/2

6:50 am-8:37 pm

2 stops14h 47m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$574

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 6/1

12:55 pm-8:06 am

2 stops20h 11m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$575

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 5/30

2:40 pm-7:20 pm

2 stops29h 40m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$576

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 6/13

2:54 pm-8:06 am

2 stops18h 12m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$578

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 6/1

12:55 pm-8:06 am

2 stops20h 11m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$587
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 6/3

6:20 am-7:20 pm

2 stops14h 00m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$588

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

6:50 am-12:35 am

3 stops42h 45m

Panama City Tocumen Intl

Tue 5/5

3:10 pm-11:53 pm

2 stops31h 43m

$591

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sun 5/31

6:50 am-7:20 pm

2 stops13h 30m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$605

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Detroit to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit and Panama City?

When to book flights from Detroit to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Panama City (DTT to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Panama City

Fastest flight time

8h 45m

Direct flights

None
The fastest flight from Detroit to Panama City takes 8h 45m
There are no direct flights from Detroit to Panama City. There are no popular flight routes from Detroit to Panama City.
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Frequently asked questions about flying from Detroit to Panama City

  • How far is Detroit to Panama City Tocumen Intl by plane?

    Detroit and Panama City Tocumen Intl are 2312.9 mi apart from one another. Flights usually cover this in 8h 45m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Detroit to Panama City Tocumen Intl Airport?

    Prices for flights from Detroit to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Detroit to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Detroit to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Detroit to Panama City

Compare and see reviews for airlines that fly from Detroit to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $611Free CancellationRating
7.5
1,574 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $628Free CancellationRating
7.1
11,569 reviews
Search American Airlines flights
United AirlinesPriceFrom $629Free CancellationRating
7.4
9,579 reviews
Search United Airlines flights
DeltaPriceFrom $668Free CancellationRating
7.9
8,406 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Detroit.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Detroit to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Detroit to Panama City?

momondo helps you find the best flight between Detroit and Panama City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.

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