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Cheap flights from Des Moines to Rome from $345

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Rome departing on 10/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Rome

Cheap round-trip flights

Enter your travel dates to find the best prices.
Air France Logo
10:23 am - 11:00 am
DSM
-
FCO
17h 37m
1 stop
Air France Logo
9:45 am - 5:50 pm
FCO
-
DSM
15h 05m
1 stop
$774Air France
Wed, Aug 12 - Wed, Aug 19
Air Canada Logo
8:00 am - 9:15 am
DSM
-
FCO
18h 15m
2 stops
Air Canada Logo
11:30 am - 11:35 pm
FCO
-
DSM
43h 05m
2 stops
$775Air Canada
Tue, Oct 13 - Thu, Oct 22
Multiple Airlines Logo
3:11 pm - 7:55 am
DSM
-
FCO
33h 44m
1 stop
Multiple Airlines Logo
12:25 pm - 12:34 pm
FCO
-
DSM
31h 09m
2 stops
$782Multiple Airlines
Tue, Oct 13 - Thu, Oct 22
Lufthansa Logo
1:21 pm - 10:00 am
DSM
-
FCO
13h 39m
2 stops
Lufthansa Logo
6:50 am - 5:28 pm
FCO
-
DSM
17h 38m
2 stops
$788Lufthansa
Mon, Aug 17 - Fri, Aug 28
Delta Logo
10:15 am - 11:00 am
DSM
-
FCO
17h 45m
1 stop
Delta Logo
9:45 am - 5:42 pm
FCO
-
DSM
14h 57m
1 stop
$792Delta
Tue, Oct 13 - Thu, Oct 22
Air Canada Logo
8:00 am - 9:15 am
DSM
-
FCO
18h 15m
2 stops
Air Canada Logo
11:30 am - 10:26 am
FCO
-
DSM
29h 56m
2 stops
$797Air Canada
Wed, Aug 12 - Wed, Aug 19
Multiple Airlines Logo
8:00 am - 9:15 am
DSM
-
FCO
18h 15m
2 stops
Multiple Airlines Logo
11:30 am - 11:35 pm
FCO
-
DSM
19h 05m
3 stops
$798Multiple Airlines
Tue, Oct 13 - Thu, Oct 22
Lufthansa Logo
1:21 pm - 10:00 am
DSM
-
FCO
13h 39m
2 stops
Lufthansa Logo
6:50 am - 5:28 pm
FCO
-
DSM
17h 38m
2 stops
$801Lufthansa
Mon, Aug 17 - Fri, Aug 28
United Airlines Logo
6:00 am - 1:15 pm
DSM
-
FCO
24h 15m
2 stops
United Airlines Logo
11:30 am - 2:16 pm
FCO
-
DSM
33h 46m
2 stops
$803United Airlines
Tue, Aug 11 - Thu, Aug 20
United Airlines Logo
5:45 am - 12:20 pm
DSM
-
FCO
23h 35m
1 stop
United Airlines Logo
11:30 am - 2:16 pm
FCO
-
DSM
33h 46m
2 stops
$804United Airlines
Tue, Aug 11 - Thu, Aug 20

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KLM flights from Des Moines to Rome Fiumicino Airport

Our best KLM deals on Des Moines to Rome Fiumicino Airport flight tickets
KLM
Aug 2
DSM2:25 pmDes Moines
13h 25m
1 stop
FCO10:50 amRome Fiumicino
Aug 20
FCO6:30 amRome Fiumicino
14h 34m
2 stops
DSM2:04 pmDes Moines
$810
KLM
Aug 2
DSM2:25 pmDes Moines
13h 25m
1 stop
FCO10:50 amRome Fiumicino
Aug 20
FCO6:30 amRome Fiumicino
14h 34m
2 stops
DSM2:04 pmDes Moines
$814
KLM
Aug 11
DSM6:35 pmDes Moines
14h 50m
2 stops
FCO4:25 pmRome Fiumicino
Aug 18
FCO7:45 pmRome Fiumicino
28h 05m
2 stops
DSM4:50 pmDes Moines
$823

Air Canada flights from Des Moines to Rome Fiumicino Airport

Our best Air Canada deals on Des Moines to Rome Fiumicino Airport flight tickets
Air Canada
Oct 13
DSM8:00 amDes Moines
18h 15m
2 stops
FCO9:15 amRome Fiumicino
Oct 22
FCO11:30 amRome Fiumicino
43h 05m
2 stops
DSM11:35 pmDes Moines
$775
Air Canada
Aug 12
DSM8:00 amDes Moines
18h 15m
2 stops
FCO9:15 amRome Fiumicino
Aug 19
FCO11:30 amRome Fiumicino
29h 56m
2 stops
DSM10:26 amDes Moines
$797
Air Canada
Aug 11
DSM8:00 amDes Moines
18h 15m
2 stops
FCO9:15 amRome Fiumicino
Aug 20
FCO11:30 amRome Fiumicino
40h 53m
2 stops
DSM9:23 pmDes Moines
$807

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Rome Fiumicino Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 29, 2026.
Use the filters below to find and compare flights from Des Moines to Rome Fiumicino Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 8/12

10:23 am-11:00 am

1 stop17h 37m

Rome Fiumicino

Wed 8/19

9:45 am-5:50 pm

1 stop15h 05m

$774

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 10/13

8:00 am-9:15 am

2 stops18h 15m

Rome Fiumicino

Thu 10/22

11:30 am-11:35 pm

2 stops43h 05m

$775

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 10/13

3:11 pm-7:55 am

1 stop33h 44m

Rome Fiumicino

Thu 10/22

12:25 pm-12:34 pm

2 stops31h 09m

$782
Quickest round-trip

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 8/17

1:21 pm-10:00 am

2 stops13h 39m

Rome Fiumicino

Fri 8/28

6:50 am-5:28 pm

2 stops17h 38m

$788

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 10/13

10:15 am-11:00 am

1 stop17h 45m

Rome Fiumicino

Thu 10/22

9:45 am-5:42 pm

1 stop14h 57m

$792

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 8/12

8:00 am-9:15 am

2 stops18h 15m

Rome Fiumicino

Wed 8/19

11:30 am-10:26 am

2 stops29h 56m

$797

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 10/13

8:00 am-9:15 am

2 stops18h 15m

Rome Fiumicino

Thu 10/22

11:30 am-11:35 pm

3 stops19h 05m

$798

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 8/17

1:21 pm-10:00 am

2 stops13h 39m

Rome Fiumicino

Fri 8/28

6:50 am-5:28 pm

2 stops17h 38m

$801

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

6:00 am-1:15 pm

2 stops24h 15m

Rome Fiumicino

Thu 8/20

11:30 am-2:16 pm

2 stops33h 46m

$803

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

5:45 am-12:20 pm

1 stop23h 35m

Rome Fiumicino

Thu 8/20

11:30 am-2:16 pm

2 stops33h 46m

$804

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Rome from

How to get the cheapest flight ticket from Des Moines to Rome Fiumicino Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Rome Fiumicino Airport?

What is the cheapest month to fly to Rome Fiumicino Airport?

The cheapest month to fly to Rome Fiumicino Airport from Des Moines is in November. Flight prices, which tend to average around $655, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome Fiumicino Airport during the month of November, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $718.

When to book flights from Des Moines to Rome Fiumicino Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Rome Fiumicino Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Rome Fiumicino Airport (DSM to FCO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Rome Fiumicino Airport

Fastest flight time

11h 34m

Direct flights

None
The fastest flight from Des Moines to Rome Fiumicino Airport takes 11h 34m
There are no direct flights from Des Moines to Rome Fiumicino Airport. There are no popular flight routes from Des Moines to Rome Fiumicino Airport.
Search flight deals

Frequently asked questions about flying from Des Moines to Rome Fiumicino Airport

  • How far is Des Moines to Rome Fiumicino by plane?

    Des Moines and Rome Fiumicino are 5051.1 mi apart from one another. 11h 34m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Rome Fiumicino Airport?

    Prices for flights from Des Moines Airport to Rome Fiumicino Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Rome Fiumicino Airport?

  • How old do you have to be to fly from Des Moines Airport to Rome Fiumicino Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Rome Fiumicino Airport.

  • What documentation or ID do you need to fly to Rome Fiumicino Airport?

    The travel and health documents required for your trip to Rome Fiumicino Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Rome Fiumicino Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Rome Fiumicino Airport?

Best airlines flying from Des Moines to Rome Fiumicino Airport

Compare and see reviews for airlines that fly from Des Moines to Rome Fiumicino Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $491Free CancellationRating
7.4
9,894 reviews
Search United Airlines flights
DeltaPriceFrom $655Free CancellationRating
7.8
8,449 reviews
Search Delta flights

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Cassino
Gaeta
Orvieto
Ponza
Montepulciano
Chianciano Terme
Ladispoli
Pienza
Tivoli
Sperlonga
Terracina
Saturnia
Ciampino
Santa Marinella
Anzio
Orbetello
Vatican
Grosseto

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Rome?

Finding the right flight to Rome from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Rome quick and easy, saving you time and money.

Can I find flights from Des Moines to Rome with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Rome from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Rome?

Once you have performed a search for Des Moines to Rome flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Rome right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Rome from Des Moines. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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