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Cheap flights from Des Moines to Johannesburg from $1,257

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Johannesburg departing on 3/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Johannesburg

Cheap round-trip flights

American Airlines Logo
1:46 pm - 7:35 amDSM-JNB
33h 49m2 stops
American Airlines Logo
10:00 pm - 6:02 pmJNB-DSM
27h 02m2 stops
$1,257American Airlines
Find Deal
Thu, Mar 5 - Mon, Mar 9
Qatar Airways Logo
3:48 pm - 3:25 pmDSM-JNB
40h 37m2 stops
Qatar Airways Logo
9:25 am - 2:56 pmJNB-DSM
37h 31m2 stops
$1,264Qatar Airways
Find Deal
Fri, Oct 31 - Fri, Nov 7
Delta Logo
5:15 pm - 7:00 pmDSM-JNB
18h 45m1 stop
Delta Logo
7:40 pm - 4:30 pmJNB-DSM
28h 50m2 stops
$1,462Delta
Find Deal
Fri, Oct 31 - Fri, Nov 7
Delta Logo
5:15 pm - 7:00 pmDSM-JNB
18h 45m1 stop
Delta Logo
7:40 pm - 10:30 pmJNB-DSM
34h 50m2 stops
$1,463Delta
Find Deal
Fri, Oct 31 - Fri, Nov 7
Virgin Atlantic Logo
5:15 pm - 7:00 pmDSM-JNB
18h 45m1 stop
Virgin Atlantic Logo
10:00 pm - 4:30 pmJNB-DSM
26h 30m2 stops
$1,474Virgin Atlantic
Find Deal
Fri, Oct 31 - Fri, Nov 7
United Airlines Logo
6:50 pm - 6:35 pmDSM-JNB
40h 45m2 stops
United Airlines Logo
7:45 pm - 10:20 pmJNB-DSM
34h 35m2 stops
$1,495United Airlines
Find Deal
Thu, Oct 30 - Thu, Nov 6
Air Canada Logo
11:35 am - 9:30 amDSM-JNB
37h 55m3 stops
Air Canada Logo
8:15 pm - 10:53 amJNB-DSM
46h 38m3 stops
$1,615Air Canada
Find Deal
Sun, Dec 7 - Mon, Dec 15
Virgin Atlantic Logo
5:15 pm - 7:00 pmDSM-JNB
18h 45m1 stop
Virgin Atlantic Logo
9:55 pm - 4:30 pmJNB-DSM
26h 35m1 stop
$1,701Virgin Atlantic
Find Deal
Fri, Oct 31 - Fri, Nov 7
Air Canada Logo
3:15 pm - 9:30 amDSM-JNB
35h 15m3 stops
Air Canada Logo
8:15 pm - 10:30 amJNB-DSM
46h 15m3 stops
$1,744Air Canada
Find Deal
Fri, Oct 31 - Fri, Nov 7
United Airlines Logo
6:50 pm - 9:30 amDSM-JNB
54h 40m2 stops
United Airlines Logo
7:45 pm - 2:33 pmJNB-DSM
26h 48m2 stops
$2,654United Airlines
Find Deal
Sat, Dec 13 - Sun, Jan 4

Air Canada flights from Des Moines to Johannesburg OR Tambo Airport

Our best Air Canada deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
Air Canada
Dec 7
DSM11:35 amDes Moines
37h 55m
3 stops
JNB9:30 amJohannesburg OR Tambo
Dec 15
JNB8:15 pmJohannesburg OR Tambo
46h 38m
3 stops
DSM10:53 amDes Moines
$1,615
Find similar
Air Canada
Oct 31
DSM3:15 pmDes Moines
35h 15m
3 stops
JNB9:30 amJohannesburg OR Tambo
Nov 7
JNB8:15 pmJohannesburg OR Tambo
46h 15m
3 stops
DSM10:30 amDes Moines
$1,744
Find similar
Air Canada
Oct 31
DSM1:05 pmDes Moines
37h 25m
3 stops
JNB9:30 amJohannesburg OR Tambo
Nov 7
JNB8:15 pmJohannesburg OR Tambo
46h 15m
3 stops
DSM10:30 amDes Moines
$1,745
Find similar

United Airlines flights from Des Moines to Johannesburg OR Tambo Airport

Our best United Airlines deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
United Airlines
Oct 30
DSM6:50 pmDes Moines
40h 45m
2 stops
JNB6:35 pmJohannesburg OR Tambo
Nov 6
JNB7:45 pmJohannesburg OR Tambo
34h 35m
2 stops
DSM10:20 pmDes Moines
$1,495
Find similar
United Airlines
Dec 13
DSM6:50 pmDes Moines
54h 40m
2 stops
JNB9:30 amJohannesburg OR Tambo
Jan 4
JNB7:45 pmJohannesburg OR Tambo
26h 48m
2 stops
DSM2:33 pmDes Moines
$2,654
Find similar
United Airlines
Dec 13
DSM3:17 pmDes Moines
58h 13m
2 stops
JNB9:30 amJohannesburg OR Tambo
Jan 4
JNB7:45 pmJohannesburg OR Tambo
47h 10m
2 stops
DSM10:55 amDes Moines
$2,659
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Johannesburg OR Tambo Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Des Moines to Johannesburg OR Tambo Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 3/5

1:46 pm-7:35 am

2 stops33h 49m

Johannesburg OR Tambo

Mon 3/9

10:00 pm-6:02 pm

2 stops27h 02m

$1,257

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 10/31

3:48 pm-3:25 pm

2 stops40h 37m

Johannesburg OR Tambo

Fri 11/7

9:25 am-2:56 pm

2 stops37h 31m

$1,264

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 10/31

5:15 pm-7:00 pm

1 stop18h 45m

Johannesburg OR Tambo

Fri 11/7

7:40 pm-4:30 pm

2 stops28h 50m

$1,462

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 10/31

5:15 pm-7:00 pm

1 stop18h 45m

Johannesburg OR Tambo

Fri 11/7

7:40 pm-10:30 pm

2 stops34h 50m

$1,463

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 10/31

5:15 pm-7:00 pm

1 stop18h 45m

Johannesburg OR Tambo

Fri 11/7

10:00 pm-4:30 pm

2 stops26h 30m

$1,474

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 10/30

6:50 pm-6:35 pm

2 stops40h 45m

Johannesburg OR Tambo

Thu 11/6

7:45 pm-10:20 pm

2 stops34h 35m

$1,495

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 12/7

11:35 am-9:30 am

3 stops37h 55m

Johannesburg OR Tambo

Mon 12/15

8:15 pm-10:53 am

3 stops46h 38m

$1,615

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 10/31

5:15 pm-7:00 pm

1 stop18h 45m

Johannesburg OR Tambo

Fri 11/7

9:55 pm-4:30 pm

1 stop26h 35m

$1,701

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Fri 10/31

3:15 pm-9:30 am

3 stops35h 15m

Johannesburg OR Tambo

Fri 11/7

8:15 pm-10:30 am

3 stops46h 15m

$1,744

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 12/13

6:50 pm-9:30 am

2 stops54h 40m

Johannesburg OR Tambo

Sun 1/4

7:45 pm-2:33 pm

2 stops26h 48m

$2,654

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Johannesburg from

How to get the cheapest flight ticket from Des Moines to Johannesburg OR Tambo Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Johannesburg OR Tambo Airport?

The month of January is, on average, the cheapest month to fly to Johannesburg OR Tambo Airport from Des Moines, with most prices found around $1,331. The month of November is another great option to travel to Johannesburg OR Tambo Airport, with average flight prices from Des Moines averaging around $1,415.

What is the cheapest day to depart on your flight to Johannesburg OR Tambo Airport?

According to our data, Wednesday is the cheapest day to fly to Johannesburg OR Tambo Airport from Des Moines. The lowest ticket price found for a Wednesday departure recently was $1,048. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Thursday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,697.

What is the cheapest time of day to depart on your flight to Johannesburg OR Tambo Airport?

Our most recent data shows that the best time of day to fly to Johannesburg OR Tambo Airport is in the afternoon. Flights from Des Moines to Johannesburg OR Tambo Airport during this time can be as low as $1,347. At noon is when there is more demand to fly to Johannesburg OR Tambo Airport, so prices are often more expensive at around $1,706 per ticket.

When to book flights from Des Moines to Johannesburg OR Tambo Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Johannesburg OR Tambo Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Johannesburg OR Tambo Airport (DSM to JNB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Johannesburg OR Tambo Airport

Direct flights

None
There are no direct flights from Des Moines to Johannesburg OR Tambo Airport. There are no popular flight routes from Des Moines to Johannesburg OR Tambo Airport.
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  • How far is Des Moines to Johannesburg OR Tambo by plane?

    Johannesburg OR Tambo is 8996.9 mi away from Des Moines. 18h 45m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

    Prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

  • How old do you have to be to fly from Des Moines Airport to Johannesburg OR Tambo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Johannesburg OR Tambo Airport.

  • What documentation or ID do you need to fly to Johannesburg OR Tambo Airport?

    The travel and health documents required for your trip to Johannesburg OR Tambo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Johannesburg OR Tambo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Johannesburg OR Tambo Airport?

Best airlines flying from Des Moines to Johannesburg OR Tambo Airport

Compare and see reviews for airlines that fly from Des Moines to Johannesburg OR Tambo Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $1,322Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $1,410Free CancellationRating
7.9
7,961 reviews
Search Delta flights

Traveling to a place near Johannesburg?

Book flights to Johannesburg if you plan to visit one of these locations
Sandton
Kempton Park
Middelburg
Edenvale

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Johannesburg?

It is quick and easy to find Des Moines to Johannesburg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Johannesburg that suits you.

Can I find flights from Des Moines to Johannesburg with flexible booking policies on momondo?

momondo does allow users to show only those flights to Johannesburg from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Johannesburg?

Once you have performed a search for Des Moines to Johannesburg flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Johannesburg right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Johannesburg flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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