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Cheap flights from Des Moines to Johannesburg from $771

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Johannesburg departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Johannesburg

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:05 am - 8:15 amDSM  Des Moines-JNB Johannesburg OR Tambo
42h 10m2 stops Chicago O'Hare Intl Abu Dhabi Zayed Intl
Multiple Airlines Logo
9:45 am - 12:04 amJNB  Johannesburg OR Tambo-DSM Des Moines
45h 19m2 stops Abu Dhabi Zayed Intl Chicago O'Hare Intl
$1,316Multiple Airlines
Thu, Sep 10 - Wed, Sep 16
Qatar Airways Logo
7:05 am - 4:00 amDSM  Des Moines-JNB Johannesburg OR Tambo
37h 55m2 stops Chicago O'Hare Intl Doha Hamad Intl
Qatar Airways Logo
2:05 pm - 7:21 pmJNB  Johannesburg OR Tambo-DSM Des Moines
36h 16m2 stops Doha Hamad Intl Chicago O'Hare Intl
$1,445Qatar Airways
Fri, Sep 25 - Fri, Oct 2
Multiple Airlines Logo
7:05 am - 7:55 amDSM  Des Moines-JNB Johannesburg OR Tambo
41h 50m2 stops Chicago O'Hare Intl Hong Kong Intl
Multiple Airlines Logo
11:10 am - 6:26 pmJNB  Johannesburg OR Tambo-DSM Des Moines
38h 16m2 stops Hong Kong Intl Los Angeles Los Angeles
$1,447Multiple Airlines
Fri, Sep 11 - Sun, Sep 20
Qatar Airways Logo
2:29 pm - 4:00 amDSM  Des Moines-JNB Johannesburg OR Tambo
30h 31m2 stops Chicago O'Hare Intl Doha Hamad Intl
Qatar Airways Logo
2:05 pm - 12:04 amJNB  Johannesburg OR Tambo-DSM Des Moines
40h 59m2 stops Doha Hamad Intl Chicago O'Hare Intl
$1,465Qatar Airways
Fri, Sep 25 - Fri, Oct 2
Qatar Airways Logo
2:29 pm - 9:10 amDSM  Des Moines-JNB Johannesburg OR Tambo
35h 41m2 stops Chicago O'Hare Intl Doha Hamad Intl
Qatar Airways Logo
8:55 pm - 7:00 pmJNB  Johannesburg OR Tambo-DSM Des Moines
29h 05m2 stops Doha Hamad Intl Chicago O'Hare Intl
$1,481Qatar Airways
Mon, Sep 28 - Mon, Oct 5
Multiple Airlines Logo
7:05 am - 7:45 amDSM  Des Moines-JNB Johannesburg OR Tambo
41h 40m2 stops Chicago O'Hare Intl Hong Kong Intl
Multiple Airlines Logo
11:10 am - 6:26 pmJNB  Johannesburg OR Tambo-DSM Des Moines
38h 16m2 stops Hong Kong Intl Los Angeles Los Angeles
$1,496Multiple Airlines
Sat, Sep 26 - Sat, Oct 3
Multiple Airlines Logo
7:05 am - 7:45 amDSM  Des Moines-JNB Johannesburg OR Tambo
41h 40m2 stops Chicago O'Hare Intl Hong Kong Intl
Multiple Airlines Logo
11:10 am - 6:26 pmJNB  Johannesburg OR Tambo-DSM Des Moines
38h 16m2 stops Hong Kong Intl Los Angeles Los Angeles
$1,497Multiple Airlines
Sat, Sep 26 - Sat, Oct 3
Delta Logo
11:31 am - 7:40 pmDSM  Des Moines-JNB Johannesburg OR Tambo
25h 09m1 stop Atlanta Hartsfield-Jackson
Delta Logo
9:55 pm - 1:49 pmJNB  Johannesburg OR Tambo-DSM Des Moines
22h 54m1 stop Atlanta Hartsfield-Jackson
$1,816Delta
Sun, Sep 27 - Sun, Oct 4
Delta Logo
2:34 pm - 7:40 pmDSM  Des Moines-JNB Johannesburg OR Tambo
22h 06m1 stop Atlanta Hartsfield-Jackson
Delta Logo
9:55 pm - 6:09 pmJNB  Johannesburg OR Tambo-DSM Des Moines
27h 14m1 stop Atlanta Hartsfield-Jackson
$1,816Delta
Mon, Sep 28 - Mon, Oct 5
Delta Logo
11:31 am - 7:40 pmDSM  Des Moines-JNB Johannesburg OR Tambo
25h 09m1 stop Atlanta Hartsfield-Jackson
Delta Logo
9:55 pm - 4:48 pmJNB  Johannesburg OR Tambo-DSM Des Moines
25h 53m2 stops Atlanta Hartsfield-Jackson Minneapolis St Paul
$1,821Delta
Sun, Sep 27 - Sun, Oct 4

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Qatar Airways flights from Des Moines to Johannesburg OR Tambo Airport

Our best Qatar Airways deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
Qatar Airways
Sep 25
DSM7:05 amDes Moines
37h 55m
2 stops
JNB4:00 amJohannesburg OR Tambo
Oct 2
JNB2:05 pmJohannesburg OR Tambo
36h 16m
2 stops
DSM7:21 pmDes Moines
$1,445
Qatar Airways
Sep 25
DSM2:29 pmDes Moines
30h 31m
2 stops
JNB4:00 amJohannesburg OR Tambo
Oct 2
JNB2:05 pmJohannesburg OR Tambo
40h 59m
2 stops
DSM12:04 amDes Moines
$1,465
Qatar Airways
Sep 28
DSM2:29 pmDes Moines
35h 41m
2 stops
JNB9:10 amJohannesburg OR Tambo
Oct 5
JNB8:55 pmJohannesburg OR Tambo
29h 05m
2 stops
DSM7:00 pmDes Moines
$1,481

Virgin Atlantic flights from Des Moines to Johannesburg OR Tambo Airport

Our best Virgin Atlantic deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
Virgin Atlantic
Sep 25
DSM2:34 pmDes Moines
22h 06m
1 stop
JNB7:40 pmJohannesburg OR Tambo
Oct 2
JNB9:55 pmJohannesburg OR Tambo
31h 31m
1 stop
DSM10:26 pmDes Moines
$1,791
Virgin Atlantic
Sep 25
DSM5:45 amDes Moines
30h 55m
1 stop
JNB7:40 pmJohannesburg OR Tambo
Oct 2
JNB9:55 pmJohannesburg OR Tambo
31h 31m
1 stop
DSM10:26 pmDes Moines
$1,801
Virgin Atlantic
Sep 27
DSM11:31 amDes Moines
25h 09m
1 stop
JNB7:40 pmJohannesburg OR Tambo
Oct 4
JNB9:55 pmJohannesburg OR Tambo
31h 31m
1 stop
DSM10:26 pmDes Moines
$1,807

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Johannesburg OR Tambo Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg OR Tambo Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Thu 9/10

7:05 am-8:15 am

2 stops42h 10m

Johannesburg OR Tambo

Wed 9/16

9:45 am-12:04 am

2 stops45h 19m

$1,316

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Fri 9/25

7:05 am-4:00 am

2 stops37h 55m

Johannesburg OR Tambo

Fri 10/2

2:05 pm-7:21 pm

2 stops36h 16m

$1,445

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Fri 9/11

7:05 am-7:55 am

2 stops41h 50m

Johannesburg OR Tambo

Sun 9/20

11:10 am-6:26 pm

2 stops38h 16m

$1,447

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Fri 9/25

2:29 pm-4:00 am

2 stops30h 31m

Johannesburg OR Tambo

Fri 10/2

2:05 pm-12:04 am

2 stops40h 59m

$1,465

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Mon 9/28

2:29 pm-9:10 am

2 stops35h 41m

Johannesburg OR Tambo

Mon 10/5

8:55 pm-7:00 pm

2 stops29h 05m

$1,481

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Sat 9/26

7:05 am-7:45 am

2 stops41h 40m

Johannesburg OR Tambo

Sat 10/3

11:10 am-6:26 pm

2 stops38h 16m

$1,496

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Sat 9/26

7:05 am-7:45 am

2 stops41h 40m

Johannesburg OR Tambo

Sat 10/3

11:10 am-6:26 pm

2 stops38h 16m

$1,497
Quickest round-trip

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Sun 9/27

11:31 am-7:40 pm

1 stop25h 09m

Johannesburg OR Tambo

Sun 10/4

9:55 pm-1:49 pm

1 stop22h 54m

$1,816

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Mon 9/28

2:34 pm-7:40 pm

1 stop22h 06m

Johannesburg OR Tambo

Mon 10/5

9:55 pm-6:09 pm

1 stop27h 14m

$1,816

Des MoinesJohannesburg

DSM Des Moines - JNB Johannesburg OR Tambo

DSMJNB

Des Moines

Sun 9/27

11:31 am-7:40 pm

1 stop25h 09m

Johannesburg OR Tambo

Sun 10/4

9:55 pm-4:48 pm

2 stops25h 53m

$1,821

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Johannesburg OR Tambo Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Des Moines to Johannesburg OR Tambo Airport flights?

You could potentially save up to 3% on your flight if you consider stops on a Des Moines to Johannesburg OR Tambo Airport flight.

When to book flights from Des Moines to Johannesburg OR Tambo Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Johannesburg OR Tambo Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Johannesburg OR Tambo Airport (DSM to JNB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Johannesburg OR Tambo Airport

Fastest flight time

25h 30m

Direct flights

None
The fastest flight from Des Moines to Johannesburg OR Tambo Airport takes 25h 30m
There are no direct flights from Des Moines to Johannesburg OR Tambo Airport. There are no popular flight routes from Des Moines to Johannesburg OR Tambo Airport.
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Frequently asked questions about flying from Des Moines to Johannesburg OR Tambo Airport

  • How far is Des Moines to Johannesburg OR Tambo by plane?

    Johannesburg OR Tambo is 8996.9 mi away from Des Moines. 25h 30m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

    Prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

  • How old do you have to be to fly from Des Moines Airport to Johannesburg OR Tambo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Johannesburg OR Tambo Airport.

  • What documentation or ID do you need to fly to Johannesburg OR Tambo Airport?

    The travel and health documents required for your trip to Johannesburg OR Tambo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Johannesburg OR Tambo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Johannesburg OR Tambo Airport?

Best airlines flying from Des Moines to Johannesburg OR Tambo Airport

Compare and see reviews for airlines that fly from Des Moines to Johannesburg OR Tambo Airport with momondo
Airline
Rating
Free Cancellation
Price
Qatar AirwaysPriceFrom $1,527Free CancellationRating
7.4
3,739 reviews
Search Qatar Airways flights
DeltaPriceFrom $1,591Free CancellationRating
7.8
8,508 reviews
Search Delta flights

Traveling to a place near Johannesburg?

Book flights to Johannesburg if you plan to visit one of these locations
Sandton
Kempton Park
Middelburg
Edenvale

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Johannesburg?

It is quick and easy to find Des Moines to Johannesburg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Johannesburg that suits you.

Can I find flights from Des Moines to Johannesburg with flexible booking policies on momondo?

momondo does allow users to show only those flights to Johannesburg from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Johannesburg?

Once you have performed a search for Des Moines to Johannesburg flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Johannesburg right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Johannesburg flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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