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Cheap flights from Des Moines to Johannesburg from $669

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Johannesburg departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Johannesburg

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:01 pm - 10:25 am
DSM
-
JNB
33h 24m2 stops
Multiple Airlines Logo
7:35 pm - 9:04 pm
JNB
-
DSM
33h 29m2 stops
$1,208Multiple Airlines
Sun, Jan 25 - Sun, Feb 1
American Airlines Logo
5:51 pm - 10:25 am
DSM
-
JNB
32h 34m2 stops
American Airlines Logo
10:00 pm - 10:50 am
JNB
-
DSM
44h 50m2 stops
$1,230American Airlines
Sun, Jan 25 - Sun, Feb 1
American Airlines Logo
4:00 pm - 7:35 am
DSM
-
JNB
31h 35m2 stops
American Airlines Logo
10:00 pm - 11:08 pm
JNB
-
DSM
33h 08m2 stops
$1,235American Airlines
Sat, Jan 24 - Sat, Jan 31
American Airlines Logo
4:00 pm - 10:25 am
DSM
-
JNB
34h 25m2 stops
American Airlines Logo
10:00 pm - 9:04 pm
JNB
-
DSM
31h 04m2 stops
$1,237American Airlines
Sun, Jan 25 - Sun, Feb 1
American Airlines Logo
4:00 pm - 10:25 am
DSM
-
JNB
34h 25m2 stops
American Airlines Logo
7:35 pm - 9:04 pm
JNB
-
DSM
33h 29m2 stops
$1,238American Airlines
Sun, Jan 25 - Sun, Feb 1
American Airlines Logo
5:51 pm - 10:25 am
DSM
-
JNB
32h 34m2 stops
American Airlines Logo
10:00 pm - 9:04 pm
JNB
-
DSM
31h 04m2 stops
$1,240American Airlines
Sun, Jan 25 - Sun, Feb 1
British Airways Logo
4:46 pm - 10:25 am
DSM
-
JNB
33h 39m2 stops
British Airways Logo
10:00 pm - 11:08 pm
JNB
-
DSM
33h 08m2 stops
$1,246British Airways
Sun, Jan 25 - Sun, Feb 1
American Airlines Logo
2:23 pm - 7:00 am
DSM
-
JNB
33h 37m2 stops
American Airlines Logo
9:15 pm - 3:53 pm
JNB
-
DSM
25h 38m2 stops
$1,360American Airlines
Wed, Jun 3 - Sat, Jun 20
British Airways Logo
5:01 pm - 10:25 am
DSM
-
JNB
33h 24m2 stops
British Airways Logo
10:00 pm - 9:04 pm
JNB
-
DSM
31h 04m2 stops
$1,393British Airways
Sat, Jan 24 - Sat, Jan 31
British Airways Logo
5:01 pm - 7:35 am
DSM
-
JNB
54h 34m2 stops
British Airways Logo
10:00 pm - 4:24 pm
JNB
-
DSM
50h 24m2 stops
$1,400British Airways
Sun, Jan 25 - Sun, Feb 1

American Airlines flights from Des Moines to Johannesburg OR Tambo Airport

Our best American Airlines deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
American Airlines
Jan 25
DSM5:51 pmDes Moines
32h 34m
2 stops
JNB10:25 amJohannesburg OR Tambo
Feb 1
JNB10:00 pmJohannesburg OR Tambo
44h 50m
2 stops
DSM10:50 amDes Moines
$1,230
Find similar
American Airlines
Jan 24
DSM4:00 pmDes Moines
31h 35m
2 stops
JNB7:35 amJohannesburg OR Tambo
Jan 31
JNB10:00 pmJohannesburg OR Tambo
33h 08m
2 stops
DSM11:08 pmDes Moines
$1,235
Find similar
American Airlines
Jan 25
DSM4:00 pmDes Moines
34h 25m
2 stops
JNB10:25 amJohannesburg OR Tambo
Feb 1
JNB10:00 pmJohannesburg OR Tambo
31h 04m
2 stops
DSM9:04 pmDes Moines
$1,237
Find similar

British Airways flights from Des Moines to Johannesburg OR Tambo Airport

Our best British Airways deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
British Airways
Jan 25
DSM4:46 pmDes Moines
33h 39m
2 stops
JNB10:25 amJohannesburg OR Tambo
Feb 1
JNB10:00 pmJohannesburg OR Tambo
33h 08m
2 stops
DSM11:08 pmDes Moines
$1,246
Find similar
British Airways
Jan 24
DSM5:01 pmDes Moines
33h 24m
2 stops
JNB10:25 amJohannesburg OR Tambo
Jan 31
JNB10:00 pmJohannesburg OR Tambo
31h 04m
2 stops
DSM9:04 pmDes Moines
$1,393
Find similar
British Airways
Jan 25
DSM5:01 pmDes Moines
54h 34m
2 stops
JNB7:35 amJohannesburg OR Tambo
Feb 1
JNB10:00 pmJohannesburg OR Tambo
50h 24m
2 stops
DSM4:24 pmDes Moines
$1,400
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Johannesburg OR Tambo Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Des Moines to Johannesburg OR Tambo Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 1/25

5:01 pm-10:25 am

2 stops33h 24m

Johannesburg OR Tambo

Sun 2/1

7:35 pm-9:04 pm

2 stops33h 29m

$1,208

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 1/25

5:51 pm-10:25 am

2 stops32h 34m

Johannesburg OR Tambo

Sun 2/1

10:00 pm-10:50 am

2 stops44h 50m

$1,230

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 1/24

4:00 pm-7:35 am

2 stops31h 35m

Johannesburg OR Tambo

Sat 1/31

10:00 pm-11:08 pm

2 stops33h 08m

$1,235

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 1/25

4:00 pm-10:25 am

2 stops34h 25m

Johannesburg OR Tambo

Sun 2/1

10:00 pm-9:04 pm

2 stops31h 04m

$1,237

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 1/25

4:00 pm-10:25 am

2 stops34h 25m

Johannesburg OR Tambo

Sun 2/1

7:35 pm-9:04 pm

2 stops33h 29m

$1,238

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 1/25

5:51 pm-10:25 am

2 stops32h 34m

Johannesburg OR Tambo

Sun 2/1

10:00 pm-9:04 pm

2 stops31h 04m

$1,240

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 1/25

4:46 pm-10:25 am

2 stops33h 39m

Johannesburg OR Tambo

Sun 2/1

10:00 pm-11:08 pm

2 stops33h 08m

$1,246

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 6/3

2:23 pm-7:00 am

2 stops33h 37m

Johannesburg OR Tambo

Sat 6/20

9:15 pm-3:53 pm

2 stops25h 38m

$1,360

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sat 1/24

5:01 pm-10:25 am

2 stops33h 24m

Johannesburg OR Tambo

Sat 1/31

10:00 pm-9:04 pm

2 stops31h 04m

$1,393

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 1/25

5:01 pm-7:35 am

2 stops54h 34m

Johannesburg OR Tambo

Sun 2/1

10:00 pm-4:24 pm

2 stops50h 24m

$1,400

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Johannesburg from

How to get the cheapest flight ticket from Des Moines to Johannesburg OR Tambo Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Johannesburg OR Tambo Airport?

According to our data, Wednesday is the cheapest day to fly to Johannesburg OR Tambo Airport from Des Moines. The lowest ticket price found for a Wednesday departure recently was $1,048. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Thursday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,697.

What is the cheapest time of day to depart on your flight to Johannesburg OR Tambo Airport?

Our most recent data shows that the best time of day to fly to Johannesburg OR Tambo Airport is in the afternoon. Flights from Des Moines to Johannesburg OR Tambo Airport during this time can be as low as $1,347. At noon is when there is more demand to fly to Johannesburg OR Tambo Airport, so prices are often more expensive at around $1,706 per ticket.

Can stopping save me money on Des Moines to Johannesburg OR Tambo Airport flights?

You could potentially save up to 12% on your flight if you consider stops on a Des Moines to Johannesburg OR Tambo Airport flight.

When to book flights from Des Moines to Johannesburg OR Tambo Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Johannesburg OR Tambo Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Johannesburg OR Tambo Airport (DSM to JNB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Johannesburg OR Tambo Airport

Fastest flight time

30h 41m

Direct flights

None
The fastest flight from Des Moines to Johannesburg OR Tambo Airport takes 30h 41m
There are no direct flights from Des Moines to Johannesburg OR Tambo Airport. There are no popular flight routes from Des Moines to Johannesburg OR Tambo Airport.
Search flight deals

  • How far is Des Moines to Johannesburg OR Tambo by plane?

    Johannesburg OR Tambo is 8996.9 mi away from Des Moines. 30h 41m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

    Prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

  • How old do you have to be to fly from Des Moines Airport to Johannesburg OR Tambo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Johannesburg OR Tambo Airport.

  • What documentation or ID do you need to fly to Johannesburg OR Tambo Airport?

    The travel and health documents required for your trip to Johannesburg OR Tambo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Johannesburg OR Tambo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Johannesburg OR Tambo Airport?

Best airlines flying from Des Moines to Johannesburg OR Tambo Airport

Compare and see reviews for airlines that fly from Des Moines to Johannesburg OR Tambo Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $1,410Free CancellationRating
7.9
8,007 reviews
Search Delta flights

Traveling to a place near Johannesburg?

Book flights to Johannesburg if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale
Middelburg

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Johannesburg?

It is quick and easy to find Des Moines to Johannesburg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Johannesburg that suits you.

Can I find flights from Des Moines to Johannesburg with flexible booking policies on momondo?

momondo does allow users to show only those flights to Johannesburg from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Johannesburg?

Once you have performed a search for Des Moines to Johannesburg flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Johannesburg right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Johannesburg flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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