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Cheap flights from Des Moines to Johannesburg from $703

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Johannesburg departing on 3/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Johannesburg

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:37 pm - 7:35 am
DSM
-
JNB
34h 58m
2 stops
American Airlines Logo
10:00 pm - 9:59 pm
JNB
-
DSM
30h 59m
2 stops
$1,264American Airlines
Wed, Mar 11 - Tue, Mar 24
American Airlines Logo
1:37 pm - 7:35 am
DSM
-
JNB
34h 58m
2 stops
American Airlines Logo
10:00 pm - 9:59 pm
JNB
-
DSM
30h 59m
2 stops
$1,265American Airlines
Wed, Mar 11 - Tue, Mar 24
Qatar Airways Logo
7:27 pm - 3:20 pm
DSM
-
JNB
60h 53m
2 stops
Qatar Airways Logo
12:40 pm - 11:59 pm
JNB
-
DSM
42h 19m
2 stops
$1,382Qatar Airways
Sun, Apr 5 - Sun, Apr 12
Qatar Airways Logo
7:27 pm - 3:20 pm
DSM
-
JNB
60h 53m
2 stops
Qatar Airways Logo
12:40 pm - 6:35 pm
JNB
-
DSM
36h 55m
2 stops
$1,383Qatar Airways
Sun, Apr 5 - Sun, Apr 12
American Airlines Logo
3:26 pm - 7:35 am
DSM
-
JNB
33h 09m
2 stops
American Airlines Logo
9:15 pm - 9:19 pm
JNB
-
DSM
31h 04m
2 stops
$1,404American Airlines
Mon, Mar 23 - Mon, Mar 30
American Airlines Logo
1:37 pm - 7:35 am
DSM
-
JNB
34h 58m
2 stops
American Airlines Logo
9:15 pm - 10:35 pm
JNB
-
DSM
32h 20m
2 stops
$1,415American Airlines
Mon, Mar 23 - Mon, Mar 30
American Airlines Logo
6:29 pm - 7:00 am
DSM
-
JNB
29h 31m
2 stops
American Airlines Logo
7:25 pm - 6:25 pm
JNB
-
DSM
30h 00m
2 stops
$1,416American Airlines
Sun, Jun 21 - Sun, Jul 12
American Airlines Logo
3:26 pm - 7:35 am
DSM
-
JNB
33h 09m
2 stops
American Airlines Logo
7:25 pm - 5:38 pm
JNB
-
DSM
29h 13m
2 stops
$1,417American Airlines
Mon, Mar 23 - Mon, Mar 30
Qatar Airways Logo
3:26 pm - 3:35 pm
DSM
-
JNB
41h 09m
2 stops
Qatar Airways Logo
2:45 pm - 11:56 pm
JNB
-
DSM
40h 11m
2 stops
$1,423Qatar Airways
Tue, Mar 24 - Tue, Mar 31
Qatar Airways Logo
1:38 pm - 3:55 am
DSM
-
JNB
30h 17m
2 stops
Qatar Airways Logo
1:45 pm - 10:34 pm
JNB
-
DSM
39h 49m
2 stops
$1,424Qatar Airways
Thu, Mar 5 - Mon, Mar 9

Qatar Airways flights from Des Moines to Johannesburg OR Tambo Airport

Our best Qatar Airways deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
Qatar Airways
Apr 5
DSM7:27 pmDes Moines
60h 53m
2 stops
JNB3:20 pmJohannesburg OR Tambo
Apr 12
JNB12:40 pmJohannesburg OR Tambo
42h 19m
2 stops
DSM11:59 pmDes Moines
$1,382
Qatar Airways
Apr 5
DSM7:27 pmDes Moines
60h 53m
2 stops
JNB3:20 pmJohannesburg OR Tambo
Apr 12
JNB12:40 pmJohannesburg OR Tambo
36h 55m
2 stops
DSM6:35 pmDes Moines
$1,383
Qatar Airways
Mar 26
DSM1:37 pmDes Moines
31h 18m
2 stops
JNB3:55 amJohannesburg OR Tambo
Apr 2
JNB2:45 pmJohannesburg OR Tambo
40h 11m
2 stops
DSM11:56 pmDes Moines
$1,385

Delta flights from Des Moines to Johannesburg OR Tambo Airport

Our best Delta deals on Des Moines to Johannesburg OR Tambo Airport flight tickets
Delta
Mar 23
DSM5:20 pmDes Moines
18h 40m
1 stop
JNB7:00 pmJohannesburg OR Tambo
Mar 30
JNB11:15 pmJohannesburg OR Tambo
28h 30m
2 stops
DSM8:45 pmDes Moines
$1,537
Delta
Mar 24
DSM11:33 amDes Moines
24h 27m
1 stop
JNB7:00 pmJohannesburg OR Tambo
Mar 31
JNB11:15 pmJohannesburg OR Tambo
28h 30m
2 stops
DSM8:45 pmDes Moines
$1,586
Delta
Mar 26
DSM11:33 amDes Moines
24h 27m
1 stop
JNB7:00 pmJohannesburg OR Tambo
Apr 2
JNB11:15 pmJohannesburg OR Tambo
28h 30m
2 stops
DSM8:45 pmDes Moines
$1,687

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Johannesburg OR Tambo Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Des Moines to Johannesburg OR Tambo Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/11

1:37 pm-7:35 am

2 stops34h 58m

Johannesburg OR Tambo

Tue 3/24

10:00 pm-9:59 pm

2 stops30h 59m

$1,264

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Wed 3/11

1:37 pm-7:35 am

2 stops34h 58m

Johannesburg OR Tambo

Tue 3/24

10:00 pm-9:59 pm

2 stops30h 59m

$1,265

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 4/5

7:27 pm-3:20 pm

2 stops60h 53m

Johannesburg OR Tambo

Sun 4/12

12:40 pm-11:59 pm

2 stops42h 19m

$1,382

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 4/5

7:27 pm-3:20 pm

2 stops60h 53m

Johannesburg OR Tambo

Sun 4/12

12:40 pm-6:35 pm

2 stops36h 55m

$1,383

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 3/23

3:26 pm-7:35 am

2 stops33h 09m

Johannesburg OR Tambo

Mon 3/30

9:15 pm-9:19 pm

2 stops31h 04m

$1,404

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 3/23

1:37 pm-7:35 am

2 stops34h 58m

Johannesburg OR Tambo

Mon 3/30

9:15 pm-10:35 pm

2 stops32h 20m

$1,415

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Sun 6/21

6:29 pm-7:00 am

2 stops29h 31m

Johannesburg OR Tambo

Sun 7/12

7:25 pm-6:25 pm

2 stops30h 00m

$1,416

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Mon 3/23

3:26 pm-7:35 am

2 stops33h 09m

Johannesburg OR Tambo

Mon 3/30

7:25 pm-5:38 pm

2 stops29h 13m

$1,417

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Tue 3/24

3:26 pm-3:35 pm

2 stops41h 09m

Johannesburg OR Tambo

Tue 3/31

2:45 pm-11:56 pm

2 stops40h 11m

$1,423

Des MoinesJohannesburg

DSM - JNB

DSMJNB

Des Moines

Thu 3/5

1:38 pm-3:55 am

2 stops30h 17m

Johannesburg OR Tambo

Mon 3/9

1:45 pm-10:34 pm

2 stops39h 49m

$1,424

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Johannesburg OR Tambo Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Johannesburg OR Tambo Airport?

Can stopping save me money on Des Moines to Johannesburg OR Tambo Airport flights?

You could potentially save up to 5% on your flight if you consider stops on a Des Moines to Johannesburg OR Tambo Airport flight.

When to book flights from Des Moines to Johannesburg OR Tambo Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Johannesburg OR Tambo Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Johannesburg OR Tambo Airport (DSM to JNB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Johannesburg OR Tambo Airport

Fastest flight time

29h 31m

Direct flights

None
The fastest flight from Des Moines to Johannesburg OR Tambo Airport takes 29h 31m
There are no direct flights from Des Moines to Johannesburg OR Tambo Airport. There are no popular flight routes from Des Moines to Johannesburg OR Tambo Airport.
Search flight deals

  • How far is Des Moines to Johannesburg OR Tambo by plane?

    Johannesburg OR Tambo is 8996.9 mi away from Des Moines. 29h 31m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

    Prices for flights from Des Moines Airport to Johannesburg OR Tambo Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Johannesburg OR Tambo Airport?

  • How old do you have to be to fly from Des Moines Airport to Johannesburg OR Tambo Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Johannesburg OR Tambo Airport.

  • What documentation or ID do you need to fly to Johannesburg OR Tambo Airport?

    The travel and health documents required for your trip to Johannesburg OR Tambo Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Johannesburg OR Tambo Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Johannesburg OR Tambo Airport?

Best airlines flying from Des Moines to Johannesburg OR Tambo Airport

Compare and see reviews for airlines that fly from Des Moines to Johannesburg OR Tambo Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $1,410Free CancellationRating
7.9
8,176 reviews
Search Delta flights

Traveling to a place near Johannesburg?

Book flights to Johannesburg if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Johannesburg?

It is quick and easy to find Des Moines to Johannesburg flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Johannesburg that suits you.

Can I find flights from Des Moines to Johannesburg with flexible booking policies on momondo?

momondo does allow users to show only those flights to Johannesburg from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Johannesburg?

Once you have performed a search for Des Moines to Johannesburg flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Johannesburg right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Johannesburg flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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