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Cheap flights from Denver to Santiago de los Caballeros from $309

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Santiago de los Caballeros departing on 7/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:05 am - 9:59 am
DEN
-
STI
25h 54m
1 stop
Frontier Logo
11:14 am - 11:04 pm
STI
-
DEN
13h 50m
1 stop
$555Frontier
Sat, Aug 1 - Sun, Aug 9
JetBlue Logo
1:59 pm - 2:25 am
DEN
-
STI
10h 26m
1 stop
JetBlue Logo
6:30 am - 11:55 am
STI
-
DEN
31h 25m
1 stop
$624JetBlue
Tue, Sep 1 - Tue, Sep 22
Frontier Logo
6:05 am - 9:59 am
DEN
-
STI
25h 54m
1 stop
Frontier Logo
11:14 am - 6:30 am
STI
-
DEN
21h 16m
2 stops
$630Frontier
Wed, Aug 5 - Tue, Aug 11
JetBlue Logo
1:59 pm - 2:25 am
DEN
-
STI
10h 26m
1 stop
JetBlue Logo
6:30 am - 11:55 am
STI
-
DEN
31h 25m
1 stop
$634JetBlue
Tue, Sep 1 - Tue, Sep 22
Frontier Logo
3:52 pm - 9:59 am
DEN
-
STI
16h 07m
2 stops
Frontier Logo
11:14 am - 11:04 pm
STI
-
DEN
13h 50m
1 stop
$636Frontier
Sat, Aug 1 - Sun, Aug 9
Copa Airlines Logo
10:43 pm - 2:59 pm
DEN
-
STI
14h 16m
1 stop
Copa Airlines Logo
4:12 pm - 6:20 pm
STI
-
DEN
28h 08m
1 stop
$650Copa Airlines
Sun, Aug 16 - Thu, Aug 20
JetBlue Logo
12:59 pm - 1:21 am
DEN
-
STI
10h 22m
1 stop
JetBlue Logo
6:01 am - 5:04 pm
STI
-
DEN
14h 03m
1 stop
$658JetBlue
Wed, Oct 21 - Wed, Nov 4
Multiple Airlines Logo
3:15 pm - 10:47 am
DEN
-
STI
17h 32m
1 stop
Multiple Airlines Logo
1:43 pm - 11:04 pm
STI
-
DEN
11h 21m
1 stop
$659Multiple Airlines
Sat, Oct 3 - Sat, Oct 10
Copa Airlines Logo
10:43 pm - 2:59 pm
DEN
-
STI
14h 16m
1 stop
Copa Airlines Logo
4:12 pm - 6:20 pm
STI
-
DEN
28h 08m
1 stop
$670Copa Airlines
Sun, Aug 16 - Thu, Aug 20
Multiple Airlines Logo
3:15 pm - 10:47 am
DEN
-
STI
17h 32m
1 stop
Multiple Airlines Logo
1:43 pm - 11:04 pm
STI
-
DEN
11h 21m
1 stop
$673Multiple Airlines
Sat, Oct 3 - Sat, Oct 10

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Copa Airlines flights from Denver to Santiago de los Caballeros

Our best Copa Airlines deals on Denver to Santiago de los Caballeros flight tickets
Copa Airlines
Aug 16
DEN10:43 pmDenver Intl
14h 16m
1 stop
STI2:59 pmSantiago de los Caballeros
Aug 20
STI4:12 pmSantiago de los Caballeros
28h 08m
1 stop
DEN6:20 pmDenver Intl
$650
Copa Airlines
Aug 16
DEN10:43 pmDenver Intl
14h 16m
1 stop
STI2:59 pmSantiago de los Caballeros
Aug 20
STI4:12 pmSantiago de los Caballeros
28h 08m
1 stop
DEN6:20 pmDenver Intl
$670
Copa Airlines
Aug 14
DEN10:43 pmDenver Intl
14h 16m
1 stop
STI2:59 pmSantiago de los Caballeros
Sep 5
STI4:12 pmSantiago de los Caballeros
27h 59m
1 stop
DEN6:11 pmDenver Intl
$696

JetBlue flights from Denver to Santiago de los Caballeros

Our best JetBlue deals on Denver to Santiago de los Caballeros flight tickets
JetBlue
Sep 1
DEN1:59 pmDenver Intl
10h 26m
1 stop
STI2:25 amSantiago de los Caballeros
Sep 22
STI6:30 amSantiago de los Caballeros
31h 25m
1 stop
DEN11:55 amDenver Intl
$624
JetBlue
Sep 1
DEN1:59 pmDenver Intl
10h 26m
1 stop
STI2:25 amSantiago de los Caballeros
Sep 22
STI6:30 amSantiago de los Caballeros
31h 25m
1 stop
DEN11:55 amDenver Intl
$634
JetBlue
Oct 21
DEN12:59 pmDenver Intl
10h 22m
1 stop
STI1:21 amSantiago de los Caballeros
Nov 4
STI6:01 amSantiago de los Caballeros
14h 03m
1 stop
DEN5:04 pmDenver Intl
$658

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Denver to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sat 8/1

6:05 am-9:59 am

1 stop25h 54m

Santiago de los Caballeros

Sun 8/9

11:14 am-11:04 pm

1 stop13h 50m

$555

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Tue 9/1

1:59 pm-2:25 am

1 stop10h 26m

Santiago de los Caballeros

Tue 9/22

6:30 am-11:55 am

1 stop31h 25m

$624

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Wed 8/5

6:05 am-9:59 am

1 stop25h 54m

Santiago de los Caballeros

Tue 8/11

11:14 am-6:30 am

2 stops21h 16m

$630

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Tue 9/1

1:59 pm-2:25 am

1 stop10h 26m

Santiago de los Caballeros

Tue 9/22

6:30 am-11:55 am

1 stop31h 25m

$634

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sat 8/1

3:52 pm-9:59 am

2 stops16h 07m

Santiago de los Caballeros

Sun 8/9

11:14 am-11:04 pm

1 stop13h 50m

$636

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sun 8/16

10:43 pm-2:59 pm

1 stop14h 16m

Santiago de los Caballeros

Thu 8/20

4:12 pm-6:20 pm

1 stop28h 08m

$650
Quickest round-trip

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Wed 10/21

12:59 pm-1:21 am

1 stop10h 22m

Santiago de los Caballeros

Wed 11/4

6:01 am-5:04 pm

1 stop14h 03m

$658

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sat 10/3

3:15 pm-10:47 am

1 stop17h 32m

Santiago de los Caballeros

Sat 10/10

1:43 pm-11:04 pm

1 stop11h 21m

$659

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sun 8/16

10:43 pm-2:59 pm

1 stop14h 16m

Santiago de los Caballeros

Thu 8/20

4:12 pm-6:20 pm

1 stop28h 08m

$670

DenverSantiago de los Caballeros

DEN - STI

DENSTI

Denver Intl

Sat 10/3

3:15 pm-10:47 am

1 stop17h 32m

Santiago de los Caballeros

Sat 10/10

1:43 pm-11:04 pm

1 stop11h 21m

$673

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Denver to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Denver is in May. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of May, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $487.

Can stopping save me money on Denver to Santiago de los Caballeros flights?

You could potentially save up to 10% on your flight if you consider stops on a Denver to Santiago de los Caballeros flight.

When to book flights from Denver to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Santiago de los Caballeros (DEN to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago de los Caballeros

Fastest flight time

10h 06m

Direct flights

None
The fastest flight from Denver to Santiago de los Caballeros takes 10h 06m
There are no direct flights from Denver to Santiago de los Caballeros. There are no popular flight routes from Denver to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Denver to Santiago de los Caballeros

  • How far is Denver Intl to Santiago de los Caballeros by plane?

    Denver Intl and Santiago de los Caballeros are 2465.7 mi apart from one another. By plane, this route typically takes 10h 06m.

  • When did momondo last update prices for flights from Denver Intl Airport to Santiago de los Caballeros Airport?

    Prices for flights from Denver Intl Airport to Santiago de los Caballeros Airport were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Denver Intl Airport to Santiago de los Caballeros Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The necessary travel and health documents for your Santiago de los Caballeros Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Denver to Santiago de los Caballeros?

Best airlines flying from Denver to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Denver to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $413Free CancellationRating
7.1
11,827 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago de los Caballeros?

Finding the right flight to Santiago de los Caballeros from Denver is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago de los Caballeros quick and easy, saving you time and money.

Can I find flights from Denver to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. All flights to Santiago de los Caballeros from Denver on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Denver to Santiago de los Caballeros?

momondo helps you find the best flight between Denver and Santiago de los Caballeros by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago de los Caballeros flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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