Which layover airport has the shortest connection time from Denver to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 2h 16m.

Which airport is the most popular layover for flights between Denver and Santiago?

Houston (IAH) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Denver to Santiago?

Flights via Miami (MIA) offer the lowest average round-trip price of $648.

Which layover airport has the shortest travel time from Denver to Santiago?

Flights connecting via Houston (IAH) have the shortest average one-way travel time: 13h 18m.

What airlines fly to Santiago?

Delta, LATAM Airlines and American Airlines are the top three most popular airlines that fly to Santiago from Denver according to our data. Delta is the first choice among our users, with 27% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 5 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

As of November 2026, there are 5 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$364 Cheap Flights from Denver to Santiago in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to Santiago

Round-trip

One-way

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Cheap round-trip flights

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3:52 pm - 7:55 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

36h 03m2 stops Miami Lima J Chavez Intl

8:35 pm - 7:39 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

39h 04m2 stops Lima J Chavez Intl Miami

$760Multiple Airlines

Thu, Nov 26 - Mon, Dec 7

9:55 pm - 11:41 pmDEN Denver Intl-SCL Santiago Arturo Merino Benitez

21h 46m1 stop Panama City Tocumen Intl

1:17 am - 5:14 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

19h 57m1 stop Panama City Tocumen Intl

$787Copa Airlines

Mon, Feb 1 - Sat, Feb 13

9:55 pm - 12:29 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

22h 34m1 stop Panama City Tocumen Intl

11:58 pm - 5:04 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

21h 06m1 stop Panama City Tocumen Intl

$787Copa Airlines

Thu, Feb 25 - Sat, Mar 6

5:05 am - 7:45 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

22h 40m1 stop Dallas/Fort Worth

11:45 pm - 8:05 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

23h 20m1 stop Dallas/Fort Worth

$800American Airlines

Mon, Mar 1 - Tue, Mar 16

10:29 am - 8:35 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

18h 06m1 stop Dallas/Fort Worth

11:45 pm - 9:47 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

14h 02m1 stop Dallas/Fort Worth

$800American Airlines

Mon, Feb 1 - Mon, Feb 22

6:30 am - 4:20 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

19h 50m2 stops Los Angeles Lima J Chavez Intl

3:50 am - 12:23 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

22h 33m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$802LATAM Airlines

Sun, Apr 18 - Mon, Apr 26

6:30 am - 5:35 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

21h 05m1 stop Los Angeles

11:25 pm - 6:10 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

20h 45m1 stop Los Angeles

$802LATAM Airlines

Fri, Apr 23 - Sat, May 1

6:41 am - 5:45 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

19h 04m2 stops Orlando Bogotá El Dorado

4:15 pm - 9:30 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

33h 15m2 stops Bogotá El Dorado Orlando

$806Multiple Airlines

Tue, Dec 1 - Tue, Dec 8

2:32 pm - 5:20 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

34h 48m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

8:25 pm - 12:55 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

20h 30m2 stops Lima J Chavez Intl Los Angeles

$836Delta

Sat, Jan 30 - Tue, Feb 16

1:01 pm - 7:40 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

14h 39m1 stop Atlanta Hartsfield-Jackson

9:50 pm - 2:33 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

20h 43m1 stop Atlanta Hartsfield-Jackson

$836Delta

Sat, Jan 30 - Mon, Feb 15

Cheap last minute flights

Enter your travel dates to find the best prices.

10:41 am - 7:40 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

16h 59m1 stop Atlanta Hartsfield-Jackson

11:55 pm - 11:56 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

16h 01m1 stop Los Angeles

$962LATAM Airlines

Sun, Nov 8 - Wed, Nov 18

8:00 am - 7:40 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

19h 40m1 stop Atlanta Hartsfield-Jackson

11:55 pm - 11:56 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

16h 01m1 stop Los Angeles

$962LATAM Airlines

Sun, Nov 8 - Wed, Nov 18

2:36 pm - 7:40 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

13h 04m1 stop Atlanta Hartsfield-Jackson

11:55 pm - 11:56 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

16h 01m1 stop Los Angeles

$962LATAM Airlines

Sun, Nov 8 - Wed, Nov 18

7:00 am - 7:30 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

20h 30m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

11:10 pm - 6:31 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

23h 21m1 stop Atlanta Hartsfield-Jackson

$1,006Delta

Wed, Nov 4 - Wed, Nov 11

7:00 am - 7:30 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

20h 30m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

11:55 pm - 5:10 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

21h 15m2 stops Los Angeles Salt Lake City

$1,010Delta

Wed, Nov 4 - Wed, Nov 11

7:33 am - 8:45 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

21h 12m2 stops Dallas/Fort Worth Miami

10:30 pm - 1:53 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

19h 23m2 stops Miami Chicago O'Hare Intl

$1,010American Airlines

Sun, Nov 8 - Wed, Nov 18

11:59 pm - 8:45 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

28h 46m1 stop Miami

10:30 pm - 10:59 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

28h 29m1 stop Miami

$1,014American Airlines

Wed, Nov 4 - Wed, Nov 11

7:33 am - 8:45 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

21h 12m2 stops Dallas/Fort Worth Miami

10:30 pm - 1:53 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

19h 23m2 stops Miami Chicago O'Hare Intl

$1,092American Airlines

Sun, Nov 8 - Wed, Nov 18

3:30 pm - 12:31 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

29h 01m2 stops New York John F Kennedy Intl Guayaquil Jose Joaquin de Olmedo

9:55 pm - 10:35 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

16h 40m1 stop Toronto Pearson Intl

$2,122Multiple Airlines

Sun, Nov 8 - Mon, Nov 16

3:30 pm - 12:31 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

29h 01m2 stops New York John F Kennedy Intl Guayaquil Jose Joaquin de Olmedo

9:55 pm - 10:35 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

16h 40m1 stop Toronto Pearson Intl

$2,122Multiple Airlines

Sun, Nov 8 - Tue, Nov 17

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American Airlines flights from Denver to Santiago

Our best American Airlines deals on Denver to Santiago flight tickets

American Airlines

Feb 1

DEN10:29 amDenver Intl

18h 06m

1 stop

SCL8:35 amSantiago Arturo Merino Benitez

Feb 22

SCL11:45 pmSantiago Arturo Merino Benitez

14h 02m

1 stop

DEN9:47 amDenver Intl

$800

American Airlines

Feb 1

DEN10:29 amDenver Intl

18h 56m

2 stops

SCL9:25 amSantiago Arturo Merino Benitez

Feb 22

SCL11:45 pmSantiago Arturo Merino Benitez

19h 30m

2 stops

DEN3:15 pmDenver Intl

$804

American Airlines

Mar 10

DEN1:16 pmDenver Intl

14h 29m

1 stop

SCL7:45 amSantiago Arturo Merino Benitez

Mar 22

SCL10:15 pmSantiago Arturo Merino Benitez

22h 06m

2 stops

DEN5:21 pmDenver Intl

$835

Delta flights from Denver to Santiago

Our best Delta deals on Denver to Santiago flight tickets

Delta

Jan 30

DEN2:32 pmDenver Intl

34h 48m

2 stops

SCL5:20 amSantiago Arturo Merino Benitez

Feb 18

SCL8:25 pmSantiago Arturo Merino Benitez

19h 16m

2 stops

DEN11:41 amDenver Intl

$836

Delta

Feb 22

DEN3:41 pmDenver Intl

19h 19m

2 stops

SCL3:00 pmSantiago Arturo Merino Benitez

Feb 27

SCL9:50 pmSantiago Arturo Merino Benitez

29h 39m

1 stop

DEN11:29 pmDenver Intl

$841

Delta

Nov 4

DEN7:00 amDenver Intl

20h 30m

2 stops

SCL7:30 amSantiago Arturo Merino Benitez

Nov 11

SCL11:55 pmSantiago Arturo Merino Benitez

21h 15m

2 stops

DEN5:10 pmDenver Intl

$1,010

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Thu 11/26

3:52 pm-7:55 am

2 stops36h 03m

Santiago Arturo Merino Benitez

Mon 12/7

8:35 pm-7:39 am

2 stops39h 04m

$760

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Mon 2/1

9:55 pm-11:41 pm

1 stop21h 46m

Santiago Arturo Merino Benitez

Sat 2/13

1:17 am-5:14 pm

1 stop19h 57m

$787

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Thu 2/25

9:55 pm-12:29 am

1 stop22h 34m

Santiago Arturo Merino Benitez

Sat 3/6

11:58 pm-5:04 pm

1 stop21h 06m

$787

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Mon 3/1

5:05 am-7:45 am

1 stop22h 40m

Santiago Arturo Merino Benitez

Tue 3/16

11:45 pm-8:05 pm

1 stop23h 20m

$800

Quickest round-trip

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Mon 2/1

10:29 am-8:35 am

1 stop18h 06m

Santiago Arturo Merino Benitez

Mon 2/22

11:45 pm-9:47 am

1 stop14h 02m

$800

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Sun 4/18

6:30 am-4:20 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Mon 4/26

3:50 am-12:23 am

2 stops22h 33m

$802

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Fri 4/23

6:30 am-5:35 am

1 stop21h 05m

Santiago Arturo Merino Benitez

Sat 5/1

11:25 pm-6:10 pm

1 stop20h 45m

$802

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Tue 12/1

6:41 am-5:45 am

2 stops19h 04m

Santiago Arturo Merino Benitez

Tue 12/8

4:15 pm-9:30 pm

2 stops33h 15m

$806

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Sat 1/30

2:32 pm-5:20 am

2 stops34h 48m

Santiago Arturo Merino Benitez

Tue 2/16

8:25 pm-12:55 pm

2 stops20h 30m

$836

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Sat 1/30

1:01 pm-7:40 am

1 stop14h 39m

Santiago Arturo Merino Benitez

Mon 2/15

9:50 pm-2:33 pm

1 stop20h 43m

$836

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Denver and Santiago?

Prices are currently typical for flights on this route.

Typical prices usually range from $664 to $959.
The lowest price recently found on this route was $760.

What is the cheapest month to fly to Santiago?

In general, June is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $755. If you don’t want to visit Santiago in June, then you should wait until May to fly from Denver, when ticket prices are also cheap, with an average price of $783.

How far in advance should I book a flight from Denver to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $908 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $651 on momondo.

Can stopping save me money on Denver to Santiago flights?

You could potentially save up to 22% on your flight if you consider stops on a Denver to Santiago flight.

How have Denver to Santiago flight prices changed over time?

As of November 2026, prices for Denver to Santiago flights are approximately 25% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Best Price Found	$364
Fastest flight time	14h 12m
Direct flights	None

The best one-way flight to Santiago from Denver in the past 72 hours is $364. The best round-trip flight deal from Denver to Santiago found on momondo in the last 72 hours is $760.

The fastest flight from Denver to Santiago takes 14h 12m

There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

Search flight deals

Frequently asked questions about flying from Denver to Santiago

How far is Denver Intl to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 14h 12m is a normal flight duration for this route.
When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
As of November 2026, there are 5 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Denver to Santiago?
Based on momondo bookings for flights between Denver and Santiago, the leading airline is Delta, making up 25% of the total bookings. Other popular airlines include LATAM Airlines with 25%, American Airlines with 24%, and United Airlines with 18%.

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $544	Free Cancellation	Rating 7.4 1,968 reviews	Search LATAM Airlines flights
Delta	PriceFrom $544	Free Cancellation	Rating 7.8 8,696 reviews	Search Delta flights
Copa Airlines	PriceFrom $552	Free Cancellation	Rating 7.6 1,552 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $593	Free Cancellation	Rating 7.0 12,230 reviews	Search American Airlines flights
United Airlines	PriceFrom $603	Free Cancellation	Rating 7.3 10,458 reviews	Search United Airlines flights

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Santa Cruz

San Fernando

Valle Nevado

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.