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Cheap flights from Denver to Santiago from $277

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Santiago departing on 12/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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LATAM Airlines Logo
12:00 pm - 7:40 amDEN-SCL
15h 40m1 stop
LATAM Airlines Logo
11:55 pm - 11:47 amSCL-DEN
15h 52m1 stop
$532LATAM Airlines
Find Deal
lun., feb. 9 - mié., feb. 25
LATAM Airlines Logo
12:00 pm - 7:40 amDEN-SCL
15h 40m1 stop
LATAM Airlines Logo
11:55 pm - 11:47 amSCL-DEN
15h 52m1 stop
$533LATAM Airlines
Find Deal
lun., feb. 9 - mié., feb. 25
LATAM Airlines Logo
12:00 pm - 6:50 amDEN-SCL
16h 50m2 stops
LATAM Airlines Logo
8:40 pm - 11:52 amSCL-DEN
17h 12m1 stop
$538LATAM Airlines
Find Deal
lun., abr. 27 - lun., may. 4
Delta Logo
12:59 am - 7:00 amDEN-SCL
26h 01m1 stop
Delta Logo
11:15 pm - 12:04 pmSCL-DEN
15h 49m1 stop
$539Delta
Find Deal
mar., mar. 3 - mar., mar. 10
Delta Logo
3:10 pm - 8:40 pmDEN-SCL
26h 30m2 stops
Delta Logo
5:15 am - 11:54 pmSCL-DEN
21h 39m2 stops
$544Delta
Find Deal
lun., mar. 23 - jue., abr. 2
LATAM Airlines Logo
1:12 pm - 5:25 pmDEN-SCL
24h 13m2 stops
LATAM Airlines Logo
8:50 pm - 6:09 pmSCL-DEN
24h 19m2 stops
$548LATAM Airlines
Find Deal
vie., feb. 27 - mar., mar. 10
LATAM Airlines Logo
3:10 pm - 2:10 pmDEN-SCL
20h 00m3 stops
LATAM Airlines Logo
10:35 pm - 11:54 pmSCL-DEN
28h 19m2 stops
$549LATAM Airlines
Find Deal
jue., mar. 26 - lun., mar. 30
United Airlines Logo
4:30 pm - 8:50 amDEN-SCL
12h 20m1 stop
United Airlines Logo
9:45 pm - 6:40 amSCL-DEN
35h 55m1 stop
$552United Airlines
Find Deal
dom., mar. 1 - dom., mar. 8
LATAM Airlines Logo
1:12 pm - 5:25 pmDEN-SCL
24h 13m2 stops
LATAM Airlines Logo
11:25 pm - 10:22 pmSCL-DEN
25h 57m2 stops
$553LATAM Airlines
Find Deal
vie., feb. 27 - mié., mar. 11
Delta Logo
12:59 am - 7:00 amDEN-SCL
27h 01m1 stop
Delta Logo
11:05 pm - 8:28 pmSCL-DEN
23h 23m2 stops
$554Delta
Find Deal
lun., mar. 16 - lun., abr. 6

United Airlines flights from Denver to Santiago

Our best United Airlines deals on Denver to Santiago flight tickets
United Airlines
Mar 1
DEN7:45 amDenver Intl
21h 05m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 8
SCL9:45 pmSantiago Arturo Merino Benitez
35h 55m
1 stop
DEN6:40 amDenver Intl
$552
Find similar
United Airlines
Feb 28
DEN8:33 pmDenver Intl
32h 17m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 8
SCL9:45 pmSantiago Arturo Merino Benitez
35h 55m
1 stop
DEN6:40 amDenver Intl
$560
Find similar
United Airlines
Mar 5
DEN4:30 pmDenver Intl
12h 20m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 11
SCL9:45 pmSantiago Arturo Merino Benitez
18h 05m
1 stop
DEN12:50 pmDenver Intl
$594
Find similar

American Airlines flights from Denver to Santiago

Our best American Airlines deals on Denver to Santiago flight tickets
American Airlines
Feb 9
DEN6:00 amDenver Intl
22h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Feb 23
SCL11:55 pmSantiago Arturo Merino Benitez
24h 25m
1 stop
DEN8:20 pmDenver Intl
$599
Find similar
American Airlines
Jan 27
DEN8:44 amDenver Intl
20h 16m
2 stops
SCL9:00 amSantiago Arturo Merino Benitez
Feb 10
SCL10:30 pmSantiago Arturo Merino Benitez
17h 04m
2 stops
DEN11:34 amDenver Intl
$604
Find similar
American Airlines
Feb 7
DEN11:59 pmDenver Intl
27h 51m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Feb 24
SCL11:15 pmSantiago Arturo Merino Benitez
16h 25m
1 stop
DEN11:40 amDenver Intl
$610
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 13, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 2/9

12:00 pm-7:40 am

1 stop15h 40m

Santiago Arturo Merino Benitez

mié. 2/25

11:55 pm-11:47 am

1 stop15h 52m

$532

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 2/9

12:00 pm-7:40 am

1 stop15h 40m

Santiago Arturo Merino Benitez

mié. 2/25

11:55 pm-11:47 am

1 stop15h 52m

$533

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 4/27

12:00 pm-6:50 am

2 stops16h 50m

Santiago Arturo Merino Benitez

lun. 5/4

8:40 pm-11:52 am

1 stop17h 12m

$538

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

mar. 3/3

12:59 am-7:00 am

1 stop26h 01m

Santiago Arturo Merino Benitez

mar. 3/10

11:15 pm-12:04 pm

1 stop15h 49m

$539

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 3/23

3:10 pm-8:40 pm

2 stops26h 30m

Santiago Arturo Merino Benitez

jue. 4/2

5:15 am-11:54 pm

2 stops21h 39m

$544

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

vie. 2/27

1:12 pm-5:25 pm

2 stops24h 13m

Santiago Arturo Merino Benitez

mar. 3/10

8:50 pm-6:09 pm

2 stops24h 19m

$548

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

jue. 3/26

3:10 pm-2:10 pm

3 stops20h 00m

Santiago Arturo Merino Benitez

lun. 3/30

10:35 pm-11:54 pm

2 stops28h 19m

$549

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

dom. 3/1

4:30 pm-8:50 am

1 stop12h 20m

Santiago Arturo Merino Benitez

dom. 3/8

9:45 pm-6:40 am

1 stop35h 55m

$552

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

vie. 2/27

1:12 pm-5:25 pm

2 stops24h 13m

Santiago Arturo Merino Benitez

mié. 3/11

11:25 pm-10:22 pm

2 stops25h 57m

$553

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 3/16

12:59 am-7:00 am

1 stop27h 01m

Santiago Arturo Merino Benitez

lun. 4/6

11:05 pm-8:28 pm

2 stops23h 23m

$554

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $681. If you don’t want to visit Santiago in September, then you should wait until October to fly from Denver, when ticket prices are also cheap, with an average price of $728.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $798. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,032.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Denver to Santiago when you can find flight prices for as low as $827. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $985 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $836 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $735 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Direct flights

None
There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.
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  • How far is Denver Intl to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 12h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Denver to Santiago?

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $551Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $563Free CancellationRating
7.5
1,876 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $575Free CancellationRating
7.6
1,565 reviews
Search Copa Airlines flights
DeltaPriceFrom $623Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $632Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
AeromexicoPriceFrom $823Free CancellationRating
7.4
1,668 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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