Cheap flights from Denver to Santiago from $345

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Santiago departing on 6/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
9:38 pm - 12:32 am
DEN
-
SCL
22h 54m
1 stop
Copa Airlines Logo
3:21 am - 5:16 pm
SCL
-
DEN
17h 55m
1 stop
$533Copa Airlines
Wed, Nov 4 - Wed, Nov 18
LATAM Airlines Logo
12:59 am - 7:45 pm
DEN
-
SCL
15h 46m
2 stops
LATAM Airlines Logo
11:00 pm - 6:04 pm
SCL
-
DEN
22h 04m
2 stops
$550LATAM Airlines
Wed, Sep 30 - Tue, Oct 6
American Airlines Logo
12:52 pm - 9:00 am
DEN
-
SCL
16h 08m
1 stop
American Airlines Logo
10:15 pm - 12:01 pm
SCL
-
DEN
17h 46m
1 stop
$553American Airlines
Sun, Nov 8 - Wed, Nov 18
American Airlines Logo
12:27 pm - 9:00 am
DEN
-
SCL
16h 33m
2 stops
American Airlines Logo
10:15 pm - 5:49 pm
SCL
-
DEN
23h 34m
2 stops
$558American Airlines
Sat, Nov 14 - Mon, Nov 23
LATAM Airlines Logo
12:00 pm - 6:55 am
DEN
-
SCL
15h 55m
2 stops
LATAM Airlines Logo
11:05 pm - 6:04 pm
SCL
-
DEN
22h 59m
2 stops
$562LATAM Airlines
Wed, Oct 21 - Wed, Nov 11
LATAM Airlines Logo
3:10 pm - 8:15 am
DEN
-
SCL
14h 05m
1 stop
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
22h 45m
1 stop
$563LATAM Airlines
Mon, Sep 28 - Wed, Nov 25
LATAM Airlines Logo
6:30 am - 5:35 am
DEN
-
SCL
20h 05m
1 stop
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
22h 45m
1 stop
$565LATAM Airlines
Thu, Oct 15 - Sun, Nov 8
LATAM Airlines Logo
6:30 am - 5:35 am
DEN
-
SCL
20h 05m
1 stop
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
22h 45m
1 stop
$568LATAM Airlines
Thu, Oct 15 - Sun, Nov 8
LATAM Airlines Logo
6:30 am - 5:35 am
DEN
-
SCL
20h 05m
1 stop
LATAM Airlines Logo
8:40 pm - 9:23 am
SCL
-
DEN
15h 43m
1 stop
$569LATAM Airlines
Sat, Sep 12 - Sun, Sep 27
LATAM Airlines Logo
12:00 pm - 6:55 am
DEN
-
SCL
16h 55m
2 stops
LATAM Airlines Logo
11:25 pm - 6:10 pm
SCL
-
DEN
21h 45m
1 stop
$573LATAM Airlines
Thu, Sep 3 - Thu, Sep 17

LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets
LATAM Airlines
Sep 30
DEN12:59 amDenver Intl
15h 46m
2 stops
SCL7:45 pmSantiago Arturo Merino Benitez
Oct 6
SCL11:00 pmSantiago Arturo Merino Benitez
22h 04m
2 stops
DEN6:04 pmDenver Intl
$550
LATAM Airlines
Oct 21
DEN12:00 pmDenver Intl
15h 55m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Nov 11
SCL11:05 pmSantiago Arturo Merino Benitez
22h 59m
2 stops
DEN6:04 pmDenver Intl
$562
LATAM Airlines
Sep 28
DEN3:10 pmDenver Intl
14h 05m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Nov 25
SCL11:25 pmSantiago Arturo Merino Benitez
22h 45m
1 stop
DEN6:10 pmDenver Intl
$563

United Airlines flights from Denver to Santiago

Our best United Airlines deals on Denver to Santiago flight tickets
United Airlines
May 29
DEN5:00 amDenver Intl
19h 20m
2 stops
SCL2:20 amSantiago Arturo Merino Benitez
Jun 9
SCL12:38 amSantiago Arturo Merino Benitez
19h 45m
2 stops
DEN6:23 pmDenver Intl
$1,094
United Airlines
May 26
DEN6:00 amDenver Intl
21h 10m
2 stops
SCL5:10 amSantiago Arturo Merino Benitez
Jun 9
SCL12:38 amSantiago Arturo Merino Benitez
21h 36m
2 stops
DEN8:14 pmDenver Intl
$1,103

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 23, 2026.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 11/4

9:38 pm-12:32 am

1 stop22h 54m

Santiago Arturo Merino Benitez

Wed 11/18

3:21 am-5:16 pm

1 stop17h 55m

$533

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 9/30

12:59 am-7:45 pm

2 stops15h 46m

Santiago Arturo Merino Benitez

Tue 10/6

11:00 pm-6:04 pm

2 stops22h 04m

$550
Quickest round-trip

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 11/8

12:52 pm-9:00 am

1 stop16h 08m

Santiago Arturo Merino Benitez

Wed 11/18

10:15 pm-12:01 pm

1 stop17h 46m

$553

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sat 11/14

12:27 pm-9:00 am

2 stops16h 33m

Santiago Arturo Merino Benitez

Mon 11/23

10:15 pm-5:49 pm

2 stops23h 34m

$558

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 10/21

12:00 pm-6:55 am

2 stops15h 55m

Santiago Arturo Merino Benitez

Wed 11/11

11:05 pm-6:04 pm

2 stops22h 59m

$562

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 9/28

3:10 pm-8:15 am

1 stop14h 05m

Santiago Arturo Merino Benitez

Wed 11/25

11:25 pm-6:10 pm

1 stop22h 45m

$563

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 10/15

6:30 am-5:35 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Sun 11/8

11:25 pm-6:10 pm

1 stop22h 45m

$565

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 10/15

6:30 am-5:35 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Sun 11/8

11:25 pm-6:10 pm

1 stop22h 45m

$568

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sat 9/12

6:30 am-5:35 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Sun 9/27

8:40 pm-9:23 am

1 stop15h 43m

$569

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 9/3

12:00 pm-6:55 am

2 stops16h 55m

Santiago Arturo Merino Benitez

Thu 9/17

11:25 pm-6:10 pm

1 stop21h 45m

$573

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Santiago from

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $673. If you don’t want to visit Santiago in September, then you should wait until January to fly from Denver, when ticket prices are also cheap, with an average price of $704.

How far in advance should I book a flight from Denver to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $780 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $583 on momondo.

Can stopping save me money on Denver to Santiago flights?

You could potentially save up to 1% on your flight if you consider stops on a Denver to Santiago flight.

How have Denver to Santiago flight prices changed over time?

As of May 2026, prices for Denver to Santiago flights are approximately 92% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time

14h 00m

Direct flights

None
The fastest flight from Denver to Santiago takes 14h 00m
There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

Frequently asked questions about flying from Denver to Santiago

  • How far is Denver Intl to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 14h 00m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Denver to Santiago?

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $369Free CancellationRating
7.5
1,575 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $539Free CancellationRating
7.4
1,918 reviews
Search LATAM Airlines flights
DeltaPriceFrom $544Free CancellationRating
7.9
8,444 reviews
Search Delta flights
United AirlinesPriceFrom $551Free CancellationRating
7.4
9,752 reviews
Search United Airlines flights
American AirlinesPriceFrom $608Free CancellationRating
7.1
11,639 reviews
Search American Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
Pichilemu
San Fernando
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Mon 6/22
Mon 6/29

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