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Cheap flights from Denver to Santiago from $336

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Santiago departing on 3/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Denver to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
10:51 pm - 7:23 pm
DEN
-
SCL
18h 32m1 stop
Copa Airlines Logo
4:09 am - 6:25 pm
SCL
-
DEN
16h 16m1 stop
$532Copa Airlines
Mon, May 11 - Wed, May 20
Delta Logo
1:35 pm - 7:00 am
DEN
-
SCL
15h 25m1 stop
Delta Logo
8:40 pm - 11:51 pm
SCL
-
DEN
29h 11m1 stop
$535Delta
Tue, May 26 - Sun, Jun 7
LATAM Airlines Logo
7:05 am - 2:05 pm
DEN
-
SCL
29h 00m2 stops
LATAM Airlines Logo
11:25 pm - 9:26 am
SCL
-
DEN
36h 01m2 stops
$544LATAM Airlines
Tue, May 26 - Fri, May 29
LATAM Airlines Logo
7:05 am - 6:35 am
DEN
-
SCL
20h 30m2 stops
LATAM Airlines Logo
10:35 am - 8:14 pm
SCL
-
DEN
36h 39m2 stops
$549LATAM Airlines
Sun, Mar 15 - Fri, Mar 27
Multiple Airlines Logo
11:05 am - 6:00 am
DEN
-
SCL
16h 55m1 stop
Multiple Airlines Logo
9:10 pm - 10:47 am
SCL
-
DEN
39h 37m2 stops
$566Multiple Airlines
Fri, May 1 - Sat, May 9
Delta Logo
12:59 am - 6:55 am
DEN
-
SCL
27h 56m2 stops
Delta Logo
8:40 pm - 11:51 pm
SCL
-
DEN
29h 11m1 stop
$572Delta
Tue, May 26 - Fri, Jun 5
Multiple Airlines Logo
11:05 am - 6:00 am
DEN
-
SCL
16h 55m1 stop
Multiple Airlines Logo
10:55 pm - 10:47 am
SCL
-
DEN
37h 52m1 stop
$575Multiple Airlines
Fri, May 1 - Sat, May 9
LATAM Airlines Logo
1:15 pm - 7:40 am
DEN
-
SCL
15h 25m1 stop
LATAM Airlines Logo
7:15 am - 8:14 pm
SCL
-
DEN
39h 59m3 stops
$582LATAM Airlines
Mon, Mar 9 - Wed, Mar 18
LATAM Airlines Logo
12:59 am - 6:55 am
DEN
-
SCL
27h 56m2 stops
LATAM Airlines Logo
9:10 pm - 11:51 pm
SCL
-
DEN
28h 41m2 stops
$587LATAM Airlines
Sun, May 10 - Wed, May 20
LATAM Airlines Logo
6:40 am - 7:40 am
DEN
-
SCL
22h 00m2 stops
LATAM Airlines Logo
10:10 pm - 7:36 pm
SCL
-
DEN
24h 26m2 stops
$592LATAM Airlines
Wed, Mar 11 - Mon, Mar 16

Copa Airlines flights from Denver to Santiago

Our best Copa Airlines deals on Denver to Santiago flight tickets
Copa Airlines
May 11
DEN10:51 pmDenver Intl
18h 32m
1 stop
SCL7:23 pmSantiago Arturo Merino Benitez
May 20
SCL4:09 amSantiago Arturo Merino Benitez
16h 16m
1 stop
DEN6:25 pmDenver Intl
$532
Find similar
Copa Airlines
Apr 9
DEN10:51 pmDenver Intl
21h 52m
1 stop
SCL10:43 pmSantiago Arturo Merino Benitez
Apr 18
SCL4:17 amSantiago Arturo Merino Benitez
16h 08m
1 stop
DEN6:25 pmDenver Intl
$607
Find similar
Copa Airlines
May 24
DEN10:51 pmDenver Intl
21h 52m
1 stop
SCL10:43 pmSantiago Arturo Merino Benitez
Jun 6
SCL12:38 amSantiago Arturo Merino Benitez
19h 47m
1 stop
DEN6:25 pmDenver Intl
$675
Find similar

United Airlines flights from Denver to Santiago

Our best United Airlines deals on Denver to Santiago flight tickets
United Airlines
Feb 7
DEN8:32 pmDenver Intl
32h 18m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Feb 24
SCL10:45 pmSantiago Arturo Merino Benitez
13h 25m
1 stop
DEN8:10 amDenver Intl
$663
Find similar
United Airlines
Jan 15
DEN3:39 pmDenver Intl
13h 11m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Feb 3
SCL10:45 pmSantiago Arturo Merino Benitez
23h 40m
1 stop
DEN6:25 pmDenver Intl
$709
Find similar
United Airlines
Jan 19
DEN3:39 pmDenver Intl
13h 11m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Feb 1
SCL10:45 pmSantiago Arturo Merino Benitez
28h 56m
1 stop
DEN11:41 pmDenver Intl
$718
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 5/11

10:51 pm-7:23 pm

1 stop18h 32m

Santiago Arturo Merino Benitez

Wed 5/20

4:09 am-6:25 pm

1 stop16h 16m

$532

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 5/26

1:35 pm-7:00 am

1 stop15h 25m

Santiago Arturo Merino Benitez

Sun 6/7

8:40 pm-11:51 pm

1 stop29h 11m

$535

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 5/26

7:05 am-2:05 pm

2 stops29h 00m

Santiago Arturo Merino Benitez

Fri 5/29

11:25 pm-9:26 am

2 stops36h 01m

$544

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/15

7:05 am-6:35 am

2 stops20h 30m

Santiago Arturo Merino Benitez

Fri 3/27

10:35 am-8:14 pm

2 stops36h 39m

$549

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 5/1

11:05 am-6:00 am

1 stop16h 55m

Santiago Arturo Merino Benitez

Sat 5/9

9:10 pm-10:47 am

2 stops39h 37m

$566

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 5/26

12:59 am-6:55 am

2 stops27h 56m

Santiago Arturo Merino Benitez

Fri 6/5

8:40 pm-11:51 pm

1 stop29h 11m

$572

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 5/1

11:05 am-6:00 am

1 stop16h 55m

Santiago Arturo Merino Benitez

Sat 5/9

10:55 pm-10:47 am

1 stop37h 52m

$575

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 3/9

1:15 pm-7:40 am

1 stop15h 25m

Santiago Arturo Merino Benitez

Wed 3/18

7:15 am-8:14 pm

3 stops39h 59m

$582

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 5/10

12:59 am-6:55 am

2 stops27h 56m

Santiago Arturo Merino Benitez

Wed 5/20

9:10 pm-11:51 pm

2 stops28h 41m

$587

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 3/11

6:40 am-7:40 am

2 stops22h 00m

Santiago Arturo Merino Benitez

Mon 3/16

10:10 pm-7:36 pm

2 stops24h 26m

$592

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Santiago from

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $673. If you don’t want to visit Santiago in September, then you should wait until October to fly from Denver, when ticket prices are also cheap, with an average price of $728.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $798. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,032.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Denver to Santiago when you can find flight prices for as low as $827. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $985 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $811 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $682 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time

12h 20m

Direct flights

None
The fastest flight from Denver to Santiago takes 12h 20m
There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.
Search flight deals

  • How far is Denver Intl to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 12h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Denver to Santiago?

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $551Free CancellationRating
7.4
9,088 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $562Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $575Free CancellationRating
7.6
1,555 reviews
Search Copa Airlines flights
DeltaPriceFrom $623Free CancellationRating
7.9
8,009 reviews
Search Delta flights
American AirlinesPriceFrom $626Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights
AeromexicoPriceFrom $823Free CancellationRating
7.4
1,646 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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