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Cheap flights from Denver to Santiago from $276

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Santiago departing on 11/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Denver to Santiago

Cheap round-trip flights

Delta Logo
7:05 am - 7:00 amDEN-SCL
19h 55m2 stops
Delta Logo
10:40 pm - 6:46 pmSCL-DEN
23h 06m1 stop
$548Delta
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Sun, Mar 1 - Fri, Mar 13
LATAM Airlines Logo
7:05 am - 7:00 amDEN-SCL
19h 55m1 stop
LATAM Airlines Logo
6:40 am - 10:49 pmSCL-DEN
20h 09m2 stops
$554LATAM Airlines
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Tue, Feb 10 - Fri, Feb 27
LATAM Airlines Logo
10:45 am - 7:00 amDEN-SCL
16h 15m2 stops
LATAM Airlines Logo
5:15 am - 10:49 pmSCL-DEN
21h 34m2 stops
$557LATAM Airlines
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Wed, Jan 21 - Tue, Feb 24
Delta Logo
7:05 am - 7:00 amDEN-SCL
19h 55m2 stops
Delta Logo
8:50 am - 11:54 pmSCL-DEN
18h 04m2 stops
$558Delta
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Sun, Mar 1 - Tue, Mar 10
United Airlines Logo
7:20 pm - 8:50 amDEN-SCL
33h 30m1 stop
United Airlines Logo
10:45 pm - 2:32 pmSCL-DEN
19h 47m1 stop
$562United Airlines
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Thu, Jan 29 - Tue, Feb 17
American Airlines Logo
12:55 pm - 9:05 amDEN-SCL
16h 10m1 stop
American Airlines Logo
10:15 pm - 1:02 pmSCL-DEN
18h 47m2 stops
$568American Airlines
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Wed, Feb 4 - Tue, Feb 24
United Airlines Logo
8:32 pm - 8:50 amDEN-SCL
32h 18m1 stop
United Airlines Logo
10:45 pm - 9:23 pmSCL-DEN
26h 38m1 stop
$570United Airlines
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Thu, Jan 29 - Tue, Feb 17
American Airlines Logo
11:37 am - 9:05 amDEN-SCL
17h 28m2 stops
American Airlines Logo
11:55 pm - 10:26 pmSCL-DEN
26h 31m1 stop
$579American Airlines
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Wed, Jan 7 - Sat, Jan 24
Copa Airlines Logo
9:38 pm - 12:32 amDEN-SCL
22h 54m1 stop
Copa Airlines Logo
3:34 am - 5:16 pmSCL-DEN
17h 42m1 stop
$606Copa Airlines
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Wed, Jan 21 - Mon, Feb 23
Copa Airlines Logo
9:38 pm - 12:32 amDEN-SCL
22h 54m1 stop
Copa Airlines Logo
1:46 am - 5:16 pmSCL-DEN
19h 30m1 stop
$626Copa Airlines
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Thu, Jan 29 - Mon, Feb 16

Delta flights from Denver to Santiago

Our best Delta deals on Denver to Santiago flight tickets
Delta
Mar 1
DEN7:05 amDenver Intl
19h 55m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Mar 13
SCL10:40 pmSantiago Arturo Merino Benitez
23h 06m
1 stop
DEN6:46 pmDenver Intl
$548
Find similar
Delta
Mar 1
DEN7:05 amDenver Intl
19h 55m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Mar 10
SCL8:50 amSantiago Arturo Merino Benitez
18h 04m
2 stops
DEN11:54 pmDenver Intl
$558
Find similar
Delta
Feb 9
DEN4:40 pmDenver Intl
34h 20m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Feb 27
SCL5:15 amSantiago Arturo Merino Benitez
21h 34m
2 stops
DEN10:49 pmDenver Intl
$563
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LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets
LATAM Airlines
Feb 10
DEN7:05 amDenver Intl
19h 55m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Feb 27
SCL6:40 amSantiago Arturo Merino Benitez
20h 09m
2 stops
DEN10:49 pmDenver Intl
$554
Find similar
LATAM Airlines
Jan 21
DEN10:45 amDenver Intl
16h 15m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Feb 24
SCL5:15 amSantiago Arturo Merino Benitez
21h 34m
2 stops
DEN10:49 pmDenver Intl
$557
Find similar
LATAM Airlines
Feb 10
DEN1:30 pmDenver Intl
13h 30m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Feb 23
SCL11:15 pmSantiago Arturo Merino Benitez
22h 55m
1 stop
DEN6:10 pmDenver Intl
$584
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/1

7:05 am-7:00 am

2 stops19h 55m

Santiago Arturo Merino Benitez

Fri 3/13

10:40 pm-6:46 pm

1 stop23h 06m

$548

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 2/10

7:05 am-7:00 am

1 stop19h 55m

Santiago Arturo Merino Benitez

Fri 2/27

6:40 am-10:49 pm

2 stops20h 09m

$554

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 1/21

10:45 am-7:00 am

2 stops16h 15m

Santiago Arturo Merino Benitez

Tue 2/24

5:15 am-10:49 pm

2 stops21h 34m

$557

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/1

7:05 am-7:00 am

2 stops19h 55m

Santiago Arturo Merino Benitez

Tue 3/10

8:50 am-11:54 pm

2 stops18h 04m

$558

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 1/29

7:20 pm-8:50 am

1 stop33h 30m

Santiago Arturo Merino Benitez

Tue 2/17

10:45 pm-2:32 pm

1 stop19h 47m

$562

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 2/4

12:55 pm-9:05 am

1 stop16h 10m

Santiago Arturo Merino Benitez

Tue 2/24

10:15 pm-1:02 pm

2 stops18h 47m

$568

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 1/29

8:32 pm-8:50 am

1 stop32h 18m

Santiago Arturo Merino Benitez

Tue 2/17

10:45 pm-9:23 pm

1 stop26h 38m

$570

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 1/7

11:37 am-9:05 am

2 stops17h 28m

Santiago Arturo Merino Benitez

Sat 1/24

11:55 pm-10:26 pm

1 stop26h 31m

$579

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 1/21

9:38 pm-12:32 am

1 stop22h 54m

Santiago Arturo Merino Benitez

Mon 2/23

3:34 am-5:16 pm

1 stop17h 42m

$606

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 1/29

9:38 pm-12:32 am

1 stop22h 54m

Santiago Arturo Merino Benitez

Mon 2/16

1:46 am-5:16 pm

1 stop19h 30m

$626

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Santiago?

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $752. If you don’t want to visit Santiago in April, then you should wait until September to fly from Denver, when ticket prices are also cheap, with an average price of $752.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $798. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,032.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Denver to Santiago when you can find flight prices for as low as $827. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $985 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $854 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $708 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Direct flights

None
There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.
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  • How far is Denver Intl to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 12h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Denver to Santiago?

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $553Free CancellationRating
7.4
8,931 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $573Free CancellationRating
7.5
1,847 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $609Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $620Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
DeltaPriceFrom $653Free CancellationRating
7.9
7,956 reviews
Search Delta flights
AeromexicoPriceFrom $803Free CancellationRating
7.4
1,697 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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