Which airport is the most popular layover for flights between Denver and Santiago?

Houston (IAH) was the most common stop: 64% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from Denver to Santiago?

Dallas (DFW) has the shortest average layover time for this route: 1h 47m.

What is the cheapest airline that flies from Denver Intl to Santiago Arturo Merino Benitez?

Air Canada, American Airlines, and LATAM Airlines are the most popular carriers operating from Denver Intl to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

American Airlines, United Airlines and LATAM Airlines are the top three most popular airlines that fly to Santiago from Denver according to our data. American Airlines is the first choice among our users, with 28% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 5 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Denver to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 13h 01m.

Which layover airport offers the lowest fares from Denver to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $625.

When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

As of July 2026, there are 5 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$319 Cheap Flights from Denver to Santiago in 2026

Q: What is the typical price of a round-trip flight between Denver and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $865 to $1,210. The lowest price recently found on this route was $581.

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to Santiago

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:49 pm - 3:38 am

DEN

SCL

25h 49m

1 stop

1:02 am - 5:02 pm

SCL

DEN

20h 00m

1 stop

$581Copa Airlines

Sun, Nov 8 - Tue, Nov 17

1:35 pm - 7:40 am

DEN

SCL

14h 05m

1 stop

11:10 pm - 6:04 pm

SCL

DEN

22h 54m

1 stop

$593Delta

Tue, Nov 10 - Wed, Nov 18

8:05 am - 6:55 am

DEN

SCL

19h 50m

2 stops

11:25 pm - 6:10 pm

SCL

DEN

22h 45m

1 stop

$598LATAM Airlines

Wed, Oct 28 - Sun, Nov 1

8:05 am - 6:55 am

DEN

SCL

19h 50m

2 stops

11:25 pm - 6:10 pm

SCL

DEN

22h 45m

1 stop

$599LATAM Airlines

Thu, Oct 15 - Sun, Nov 8

5:25 pm - 8:50 am

DEN

SCL

35h 25m

1 stop

10:45 pm - 12:12 pm

SCL

DEN

17h 27m

1 stop

$601United Airlines

Sat, Nov 7 - Wed, Nov 18

8:05 am - 1:25 pm

DEN

SCL

26h 20m

3 stops

10:30 am - 10:30 am

SCL

DEN

27h 00m

1 stop

$608Multiple Airlines

Wed, Oct 7 - Tue, Oct 13

7:15 am - 8:15 am

DEN

SCL

22h 00m

1 stop

9:40 pm - 6:04 pm

SCL

DEN

23h 24m

1 stop

$614LATAM Airlines

Mon, Oct 5 - Mon, Oct 12

7:15 am - 8:15 am

DEN

SCL

22h 00m

1 stop

12:00 am - 6:04 pm

SCL

DEN

21h 04m

2 stops

$624LATAM Airlines

Mon, Oct 5 - Mon, Oct 12

4:40 pm - 5:40 am

DEN

SCL

33h 00m

2 stops

4:00 pm - 12:23 am

SCL

DEN

36h 23m

2 stops

$625LATAM Airlines

Sun, Nov 8 - Wed, Nov 18

12:50 am - 5:35 am

DEN

SCL

25h 45m

2 stops

12:00 am - 6:04 pm

SCL

DEN

21h 04m

2 stops

$629LATAM Airlines

Sun, Oct 4 - Mon, Oct 12

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Delta flights from Denver to Santiago

Our best Delta deals on Denver to Santiago flight tickets

Delta

Nov 10

DEN1:35 pmDenver Intl

14h 05m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Nov 18

SCL11:10 pmSantiago Arturo Merino Benitez

22h 54m

1 stop

DEN6:04 pmDenver Intl

$593

Delta

Aug 16

DEN12:50 amDenver Intl

27h 05m

2 stops

SCL5:55 amSantiago Arturo Merino Benitez

Sep 2

SCL11:25 pmSantiago Arturo Merino Benitez

17h 37m

2 stops

DEN3:02 pmDenver Intl

$708

Delta

Oct 15

DEN8:05 amDenver Intl

19h 50m

2 stops

SCL6:55 amSantiago Arturo Merino Benitez

Nov 8

SCL11:25 pmSantiago Arturo Merino Benitez

19h 44m

2 stops

DEN3:09 pmDenver Intl

$714

LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets

LATAM Airlines

Oct 28

DEN8:05 amDenver Intl

19h 50m

2 stops

SCL6:55 amSantiago Arturo Merino Benitez

Nov 1

SCL11:05 pmSantiago Arturo Merino Benitez

28h 09m

2 stops

DEN11:14 pmDenver Intl

$598

LATAM Airlines

Oct 15

DEN8:05 amDenver Intl

19h 50m

2 stops

SCL6:55 amSantiago Arturo Merino Benitez

Nov 8

SCL11:25 pmSantiago Arturo Merino Benitez

22h 45m

1 stop

DEN6:10 pmDenver Intl

$599

LATAM Airlines

Oct 5

DEN7:15 amDenver Intl

22h 00m

1 stop

SCL8:15 amSantiago Arturo Merino Benitez

Oct 12

SCL9:40 pmSantiago Arturo Merino Benitez

23h 24m

1 stop

DEN6:04 pmDenver Intl

$614

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 11/8

9:49 pm-3:38 am

1 stop25h 49m

Santiago Arturo Merino Benitez

Tue 11/17

1:02 am-5:02 pm

1 stop20h 00m

$581

Quickest round-trip

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 11/10

1:35 pm-7:40 am

1 stop14h 05m

Santiago Arturo Merino Benitez

Wed 11/18

11:10 pm-6:04 pm

1 stop22h 54m

$593

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 10/28

8:05 am-6:55 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Sun 11/1

11:25 pm-6:10 pm

1 stop22h 45m

$598

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 10/15

8:05 am-6:55 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Sun 11/8

11:25 pm-6:10 pm

1 stop22h 45m

$599

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sat 11/7

5:25 pm-8:50 am

1 stop35h 25m

Santiago Arturo Merino Benitez

Wed 11/18

10:45 pm-12:12 pm

1 stop17h 27m

$601

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 10/7

8:05 am-1:25 pm

3 stops26h 20m

Santiago Arturo Merino Benitez

Tue 10/13

10:30 am-10:30 am

1 stop27h 00m

$608

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 10/5

7:15 am-8:15 am

1 stop22h 00m

Santiago Arturo Merino Benitez

Mon 10/12

9:40 pm-6:04 pm

1 stop23h 24m

$614

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 10/5

7:15 am-8:15 am

1 stop22h 00m

Santiago Arturo Merino Benitez

Mon 10/12

12:00 am-6:04 pm

2 stops21h 04m

$624

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 11/8

4:40 pm-5:40 am

2 stops33h 00m

Santiago Arturo Merino Benitez

Wed 11/18

4:00 pm-12:23 am

2 stops36h 23m

$625

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 10/4

12:50 am-5:35 am

2 stops25h 45m

Santiago Arturo Merino Benitez

Mon 10/12

12:00 am-6:04 pm

2 stops21h 04m

$629

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Denver and Santiago?

What is the cheapest month to fly to Santiago?

In general, January is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $679. If you don’t want to visit Santiago in January, then you should wait until September to fly from Denver, when ticket prices are also cheap, with an average price of $681.

How far in advance should I book a flight from Denver to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $801 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $588 on momondo.

Can stopping save me money on Denver to Santiago flights?

You could potentially save up to 30% on your flight if you consider stops on a Denver to Santiago flight.

How have Denver to Santiago flight prices changed over time?

As of July 2026, prices for Denver to Santiago flights are approximately 5% cheaper when compared to flights at the same time last year.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time	12h 29m
Direct flights	None

The fastest flight from Denver to Santiago takes 12h 29m

There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

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Frequently asked questions about flying from Denver to Santiago

How far is Denver Intl to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 12h 29m is a normal flight duration for this route.
When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
As of July 2026, there are 5 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Denver to Santiago?
Based on momondo bookings for flights between Denver and Santiago, the leading airline is American Airlines, making up 26% of the total bookings. Other popular airlines include United Airlines with 24%, LATAM Airlines with 22%, and Delta with 22%.

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $544	Free Cancellation	Rating 7.4 1,946 reviews	Search LATAM Airlines flights
Delta	PriceFrom $544	Free Cancellation	Rating 7.8 8,452 reviews	Search Delta flights
United Airlines	PriceFrom $551	Free Cancellation	Rating 7.4 9,921 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $552	Free Cancellation	Rating 7.6 1,565 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $593	Free Cancellation	Rating 7.1 11,769 reviews	Search American Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.