What airlines fly to Santiago?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Santiago from Denver according to our data. American Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 6 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Denver to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 13h 01m.

Which airport is the most popular layover for flights between Denver and Santiago?

Houston (IAH) was the most common stop: 69% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Denver to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $625.

Which layover airport has the shortest connection time from Denver to Santiago?

Dallas (DFW) has the shortest average layover time for this route: 1h 47m.

When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

As of February 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$325 Cheap Flights from Denver to Santiago in 2026

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Find the cheapest flights from Denver to Santiago

Round-trip

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Cheap round-trip flights

Enter your travel dates to find the best prices.

11:05 pm - 5:30 am

DEN

SCL

28h 25m

2 stops

10:30 am - 10:30 am

SCL

DEN

26h 00m

1 stop

$573Multiple Airlines

Sat, Apr 25 - Tue, May 5

6:05 am - 6:00 am

DEN

SCL

21h 55m

2 stops

7:45 am - 11:45 pm

SCL

DEN

19h 00m

2 stops

$585Delta

Tue, Jun 16 - Thu, Oct 1

11:05 pm - 9:05 pm

DEN

SCL

20h 00m

2 stops

10:30 am - 9:09 am

SCL

DEN

24h 39m

1 stop

$587Multiple Airlines

Sat, Apr 25 - Fri, May 8

4:40 pm - 5:25 pm

DEN

SCL

22h 45m

2 stops

11:00 pm - 11:45 pm

SCL

DEN

27h 45m

2 stops

$590LATAM Airlines

Sun, Jun 14 - Sat, Oct 3

11:05 pm - 5:30 am

DEN

SCL

28h 25m

2 stops

10:30 am - 10:30 am

SCL

DEN

26h 00m

1 stop

$592Multiple Airlines

Tue, Apr 21 - Tue, Apr 28

12:59 pm - 4:50 am

DEN

SCL

37h 51m

2 stops

11:05 pm - 5:58 pm

SCL

DEN

20h 53m

2 stops

$593LATAM Airlines

Fri, Jul 17 - Wed, Jul 22

9:35 am - 5:35 am

DEN

SCL

18h 00m

1 stop

8:40 pm - 11:45 pm

SCL

DEN

29h 05m

1 stop

$594Multiple Airlines

Tue, Jun 9 - Sun, Jul 5

11:05 pm - 9:05 pm

DEN

SCL

20h 00m

2 stops

11:00 pm - 8:27 am

SCL

DEN

35h 27m

1 stop

$595Multiple Airlines

Sat, Apr 25 - Wed, May 6

4:40 pm - 6:00 am

DEN

SCL

35h 20m

2 stops

8:40 pm - 11:45 pm

SCL

DEN

29h 05m

1 stop

$603LATAM Airlines

Tue, Jul 7 - Wed, Jul 22

11:05 pm - 5:30 am

DEN

SCL

28h 25m

2 stops

10:30 am - 9:09 am

SCL

DEN

24h 39m

1 stop

$606Multiple Airlines

Tue, Apr 21 - Fri, May 8

LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets

LATAM Airlines

Jun 14

DEN4:40 pmDenver Intl

22h 45m

2 stops

SCL5:25 pmSantiago Arturo Merino Benitez

Oct 3

SCL11:00 pmSantiago Arturo Merino Benitez

27h 45m

2 stops

DEN11:45 pmDenver Intl

$590

LATAM Airlines

Jul 17

DEN12:59 pmDenver Intl

37h 51m

2 stops

SCL4:50 amSantiago Arturo Merino Benitez

Jul 22

SCL11:05 pmSantiago Arturo Merino Benitez

20h 53m

2 stops

DEN5:58 pmDenver Intl

$593

LATAM Airlines

Jul 7

DEN4:40 pmDenver Intl

35h 20m

2 stops

SCL6:00 amSantiago Arturo Merino Benitez

Jul 22

SCL8:40 pmSantiago Arturo Merino Benitez

29h 05m

1 stop

DEN11:45 pmDenver Intl

$603

Delta flights from Denver to Santiago

Our best Delta deals on Denver to Santiago flight tickets

Delta

Jun 16

DEN6:05 amDenver Intl

21h 55m

2 stops

SCL6:00 amSantiago Arturo Merino Benitez

Sep 30

SCL7:45 pmSantiago Arturo Merino Benitez

21h 22m

2 stops

DEN2:07 pmDenver Intl

$585

Delta

Jun 22

DEN12:59 amDenver Intl

27h 56m

2 stops

SCL6:55 amSantiago Arturo Merino Benitez

Jul 14

SCL11:00 pmSantiago Arturo Merino Benitez

26h 45m

2 stops

DEN11:45 pmDenver Intl

$700

Delta

Mar 28

DEN11:43 amDenver Intl

17h 32m

1 stop

SCL8:15 amSantiago Arturo Merino Benitez

Apr 5

SCL8:40 pmSantiago Arturo Merino Benitez

29h 29m

1 stop

DEN12:09 amDenver Intl

$701

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sat 4/25

11:05 pm-5:30 am

2 stops28h 25m

Santiago Arturo Merino Benitez

Tue 5/5

10:30 am-10:30 am

1 stop26h 00m

$573

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 6/16

6:05 am-6:00 am

2 stops21h 55m

Santiago Arturo Merino Benitez

Thu 10/1

7:45 am-11:45 pm

2 stops19h 00m

$585

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sat 4/25

11:05 pm-9:05 pm

2 stops20h 00m

Santiago Arturo Merino Benitez

Fri 5/8

10:30 am-9:09 am

1 stop24h 39m

$587

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 6/14

4:40 pm-5:25 pm

2 stops22h 45m

Santiago Arturo Merino Benitez

Sat 10/3

11:00 pm-11:45 pm

2 stops27h 45m

$590

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 4/21

11:05 pm-5:30 am

2 stops28h 25m

Santiago Arturo Merino Benitez

Tue 4/28

10:30 am-10:30 am

1 stop26h 00m

$592

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 7/17

12:59 pm-4:50 am

2 stops37h 51m

Santiago Arturo Merino Benitez

Wed 7/22

11:05 pm-5:58 pm

2 stops20h 53m

$593

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 6/9

9:35 am-5:35 am

1 stop18h 00m

Santiago Arturo Merino Benitez

Sun 7/5

8:40 pm-11:45 pm

1 stop29h 05m

$594

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sat 4/25

11:05 pm-9:05 pm

2 stops20h 00m

Santiago Arturo Merino Benitez

Wed 5/6

11:00 pm-8:27 am

1 stop35h 27m

$595

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 7/7

4:40 pm-6:00 am

2 stops35h 20m

Santiago Arturo Merino Benitez

Wed 7/22

8:40 pm-11:45 pm

1 stop29h 05m

$603

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 4/21

11:05 pm-5:30 am

2 stops28h 25m

Santiago Arturo Merino Benitez

Fri 5/8

10:30 am-9:09 am

1 stop24h 39m

$606

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $663. If you don’t want to visit Santiago in September, then you should wait until April to fly from Denver, when ticket prices are also cheap, with an average price of $732.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $814 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $608 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time	16h 28m
Direct flights	None

The fastest flight from Denver to Santiago takes 16h 28m

There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

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How far is Denver Intl to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 16h 28m is a normal flight duration for this route.
When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
As of February 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Denver to Santiago?
Based on momondo bookings for flights between Denver and Santiago, the leading airline is American Airlines, making up 30% of the total bookings. Other popular airlines include Delta with 21%, United Airlines with 19%, and LATAM Airlines with 17%.

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $369	Free Cancellation	Rating 7.5 1,559 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $537	Free Cancellation	Rating 7.5 1,918 reviews	Search LATAM Airlines flights
Delta	PriceFrom $544	Free Cancellation	Rating 7.9 8,135 reviews	Search Delta flights
United Airlines	PriceFrom $551	Free Cancellation	Rating 7.4 9,232 reviews	Search United Airlines flights
American Airlines	PriceFrom $613	Free Cancellation	Rating 7.2 11,213 reviews	Search American Airlines flights
Aeromexico	PriceFrom $823	Free Cancellation	Rating 7.4 1,583 reviews	Search Aeromexico flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.