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Cheap flights from Denver to Santiago from $323

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Santiago departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Copa Airlines Logo
10:48 pm - 12:34 amDEN-SCL
22h 46m1 stop
Copa Airlines Logo
5:11 am - 6:16 pmSCL-DEN
16h 05m1 stop
$532Copa Airlines
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Mon, Mar 23 - Wed, Apr 1
United Airlines Logo
4:30 pm - 8:50 amDEN-SCL
12h 20m1 stop
United Airlines Logo
9:45 pm - 10:00 amSCL-DEN
15h 15m1 stop
$544United Airlines
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Sun, Mar 1 - Sun, Mar 8
LATAM Airlines Logo
7:05 am - 5:35 amDEN-SCL
19h 30m2 stops
LATAM Airlines Logo
11:05 pm - 6:10 pmSCL-DEN
22h 05m2 stops
$547LATAM Airlines
Find Deal
Mon, Mar 23 - Tue, Mar 31
LATAM Airlines Logo
1:30 pm - 7:00 amDEN-SCL
14h 30m1 stop
LATAM Airlines Logo
10:35 am - 12:04 pmSCL-DEN
28h 29m2 stops
$549LATAM Airlines
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Sun, Mar 15 - Fri, Mar 27
Delta Logo
6:05 am - 5:35 amDEN-SCL
20h 30m2 stops
Delta Logo
11:25 pm - 6:10 pmSCL-DEN
21h 45m2 stops
$569Delta
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Mon, Mar 23 - Wed, Apr 1
Delta Logo
12:59 am - 7:00 amDEN-SCL
27h 01m1 stop
Delta Logo
11:05 pm - 6:10 pmSCL-DEN
22h 05m2 stops
$574Delta
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Sun, Mar 22 - Tue, Mar 31
Multiple Airlines Logo
12:59 am - 5:35 amDEN-SCL
25h 36m2 stops
Multiple Airlines Logo
7:15 am - 12:08 pmSCL-DEN
31h 53m2 stops
$579Multiple Airlines
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Sun, Mar 22 - Tue, Mar 31
Multiple Airlines Logo
12:34 am - 10:15 pmDEN-SCL
18h 41m2 stops
Multiple Airlines Logo
11:25 pm - 11:16 amSCL-DEN
15h 51m1 stop
$633Multiple Airlines
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Wed, Oct 29 - Wed, Nov 19
American Airlines Logo
6:00 am - 7:50 amDEN-SCL
21h 50m1 stop
American Airlines Logo
11:15 pm - 3:48 pmSCL-DEN
20h 33m1 stop
$664American Airlines
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Mon, Feb 9 - Mon, Feb 23
American Airlines Logo
6:00 am - 7:50 amDEN-SCL
21h 50m1 stop
American Airlines Logo
11:55 pm - 3:48 pmSCL-DEN
19h 53m2 stops
$669American Airlines
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Mon, Feb 9 - Mon, Feb 23

United Airlines flights from Denver to Santiago

Our best United Airlines deals on Denver to Santiago flight tickets
United Airlines
Mar 1
DEN4:30 pmDenver Intl
12h 20m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 8
SCL9:45 pmSantiago Arturo Merino Benitez
15h 15m
1 stop
DEN10:00 amDenver Intl
$544
Find similar
United Airlines
Mar 1
DEN7:45 amDenver Intl
21h 05m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 8
SCL9:45 pmSantiago Arturo Merino Benitez
27h 25m
1 stop
DEN10:10 pmDenver Intl
$552
Find similar
United Airlines
Feb 22
DEN7:45 amDenver Intl
21h 05m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 2
SCL10:45 pmSantiago Arturo Merino Benitez
19h 47m
1 stop
DEN2:32 pmDenver Intl
$554
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LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets
LATAM Airlines
Mar 23
DEN7:05 amDenver Intl
19h 30m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Mar 31
SCL11:05 pmSantiago Arturo Merino Benitez
22h 05m
2 stops
DEN6:10 pmDenver Intl
$547
Find similar
LATAM Airlines
Mar 15
DEN1:30 pmDenver Intl
14h 30m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Mar 27
SCL10:35 amSantiago Arturo Merino Benitez
28h 29m
2 stops
DEN12:04 pmDenver Intl
$549
Find similar
LATAM Airlines
Mar 23
DEN10:45 amDenver Intl
17h 15m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Mar 31
SCL11:05 pmSantiago Arturo Merino Benitez
22h 05m
2 stops
DEN6:10 pmDenver Intl
$558
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 3/23

10:48 pm-12:34 am

1 stop22h 46m

Santiago Arturo Merino Benitez

Wed 4/1

5:11 am-6:16 pm

1 stop16h 05m

$532

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/1

4:30 pm-8:50 am

1 stop12h 20m

Santiago Arturo Merino Benitez

Sun 3/8

9:45 pm-10:00 am

1 stop15h 15m

$544

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 3/23

7:05 am-5:35 am

2 stops19h 30m

Santiago Arturo Merino Benitez

Tue 3/31

11:05 pm-6:10 pm

2 stops22h 05m

$547

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/15

1:30 pm-7:00 am

1 stop14h 30m

Santiago Arturo Merino Benitez

Fri 3/27

10:35 am-12:04 pm

2 stops28h 29m

$549

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 3/23

6:05 am-5:35 am

2 stops20h 30m

Santiago Arturo Merino Benitez

Wed 4/1

11:25 pm-6:10 pm

2 stops21h 45m

$569

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/22

12:59 am-7:00 am

1 stop27h 01m

Santiago Arturo Merino Benitez

Tue 3/31

11:05 pm-6:10 pm

2 stops22h 05m

$574

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/22

12:59 am-5:35 am

2 stops25h 36m

Santiago Arturo Merino Benitez

Tue 3/31

7:15 am-12:08 pm

2 stops31h 53m

$579

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 10/29

12:34 am-10:15 pm

2 stops18h 41m

Santiago Arturo Merino Benitez

Wed 11/19

11:25 pm-11:16 am

1 stop15h 51m

$633

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 2/9

6:00 am-7:50 am

1 stop21h 50m

Santiago Arturo Merino Benitez

Mon 2/23

11:15 pm-3:48 pm

1 stop20h 33m

$664

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 2/9

6:00 am-7:50 am

1 stop21h 50m

Santiago Arturo Merino Benitez

Mon 2/23

11:55 pm-3:48 pm

2 stops19h 53m

$669

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $681. If you don’t want to visit Santiago in September, then you should wait until April to fly from Denver, when ticket prices are also cheap, with an average price of $752.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $798. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,032.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Denver to Santiago when you can find flight prices for as low as $827. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $985 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $842 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $708 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Direct flights

None
There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.
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  • How far is Denver Intl to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 12h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Denver to Santiago?

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $551Free CancellationRating
7.4
8,975 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $573Free CancellationRating
7.5
1,865 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $575Free CancellationRating
7.6
1,547 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $613Free CancellationRating
7.2
11,039 reviews
Search American Airlines flights
DeltaPriceFrom $653Free CancellationRating
7.9
7,972 reviews
Search Delta flights
AeromexicoPriceFrom $803Free CancellationRating
7.4
1,685 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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