Which layover airport has the shortest travel time from Denver to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 13h 01m.

Which layover airport offers the lowest fares from Denver to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $625.

Which airport is the most popular layover for flights between Denver and Santiago?

Houston (IAH) was the most common stop: 69% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to Santiago?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Santiago from Denver according to our data. American Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 6 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Denver to Santiago?

Dallas (DFW) has the shortest average layover time for this route: 1h 47m.

When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

As of March 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$254 Cheap Flights from Denver to Santiago in 2026

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11:49 pm - 1:30 pm

DEN

SCL

35h 41m

2 stops

12:55 am - 9:40 am

SCL

DEN

34h 45m

2 stops

$642Multiple Airlines

Tue, Apr 7 - Mon, Apr 13

11:49 pm - 5:11 am

DEN

SCL

50h 22m

2 stops

10:30 am - 9:40 am

SCL

DEN

25h 10m

1 stop

$683Multiple Airlines

Tue, Mar 31 - Tue, Apr 28

9:49 am - 7:15 am

DEN

SCL

19h 26m

1 stop

11:25 pm - 5:35 pm

SCL

DEN

20h 10m

1 stop

$734LATAM Airlines

Tue, May 19 - Sun, May 24

11:25 am - 7:15 am

DEN

SCL

17h 50m

1 stop

11:05 pm - 5:57 pm

SCL

DEN

20h 52m

2 stops

$745LATAM Airlines

Wed, May 20 - Tue, May 26

10:51 pm - 7:23 pm

DEN

SCL

18h 32m

1 stop

12:38 am - 6:25 pm

SCL

DEN

19h 47m

1 stop

$753Copa Airlines

Fri, May 8 - Thu, May 14

11:25 am - 5:35 am

DEN

SCL

16h 10m

2 stops

11:25 pm - 5:35 pm

SCL

DEN

20h 10m

1 stop

$767LATAM Airlines

Tue, May 19 - Sun, May 24

7:20 am - 5:35 am

DEN

SCL

20h 15m

2 stops

11:05 pm - 5:57 pm

SCL

DEN

20h 52m

2 stops

$784LATAM Airlines

Tue, May 19 - Sun, May 24

6:30 am - 5:35 am

DEN

SCL

21h 05m

1 stop

11:00 pm - 8:19 pm

SCL

DEN

23h 19m

2 stops

$791LATAM Airlines

Mon, Apr 6 - Mon, Apr 13

7:20 am - 7:15 am

DEN

SCL

21h 55m

1 stop

8:40 pm - 11:18 am

SCL

DEN

16h 38m

1 stop

$795Delta

Mon, May 18 - Sat, May 23

11:05 pm - 5:35 am

DEN

SCL

28h 30m

1 stop

5:00 am - 9:40 am

SCL

DEN

30h 40m

2 stops

$800Multiple Airlines

Tue, Apr 21 - Tue, Apr 28

Copa Airlines flights from Denver to Santiago

Our best Copa Airlines deals on Denver to Santiago flight tickets

Copa Airlines

Aug 24

DEN10:43 pmDenver Intl

22h 00m

1 stop

SCL10:43 pmSantiago Arturo Merino Benitez

Sep 9

SCL3:56 amSantiago Arturo Merino Benitez

17h 15m

1 stop

DEN6:11 pmDenver Intl

$623

Copa Airlines

Aug 24

DEN10:43 pmDenver Intl

22h 00m

1 stop

SCL10:43 pmSantiago Arturo Merino Benitez

Sep 9

SCL3:56 amSantiago Arturo Merino Benitez

17h 15m

1 stop

DEN6:11 pmDenver Intl

$673

Copa Airlines

Aug 2

DEN10:43 pmDenver Intl

22h 00m

1 stop

SCL10:43 pmSantiago Arturo Merino Benitez

Aug 21

SCL4:46 amSantiago Arturo Merino Benitez

15h 34m

1 stop

DEN6:20 pmDenver Intl

$693

American Airlines flights from Denver to Santiago

Our best American Airlines deals on Denver to Santiago flight tickets

American Airlines

Aug 5

DEN1:45 pmDenver Intl

15h 05m

1 stop

SCL6:50 amSantiago Arturo Merino Benitez

Aug 12

SCL8:30 pmSantiago Arturo Merino Benitez

17h 42m

1 stop

DEN12:12 pmDenver Intl

$638

American Airlines

Aug 5

DEN8:20 amDenver Intl

20h 30m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Aug 12

SCL8:30 pmSantiago Arturo Merino Benitez

17h 21m

2 stops

DEN11:51 amDenver Intl

$641

American Airlines

Aug 5

DEN9:41 amDenver Intl

19h 09m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Aug 12

SCL8:30 pmSantiago Arturo Merino Benitez

21h 23m

2 stops

DEN3:53 pmDenver Intl

$643

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 4/7

11:49 pm-1:30 pm

2 stops35h 41m

Santiago Arturo Merino Benitez

Mon 4/13

12:55 am-9:40 am

2 stops34h 45m

$642

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 3/31

11:49 pm-5:11 am

2 stops50h 22m

Santiago Arturo Merino Benitez

Tue 4/28

10:30 am-9:40 am

1 stop25h 10m

$683

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 5/19

9:49 am-7:15 am

1 stop19h 26m

Santiago Arturo Merino Benitez

Sun 5/24

11:25 pm-5:35 pm

1 stop20h 10m

$734

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 5/20

11:25 am-7:15 am

1 stop17h 50m

Santiago Arturo Merino Benitez

Tue 5/26

11:05 pm-5:57 pm

2 stops20h 52m

$745

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 5/8

10:51 pm-7:23 pm

1 stop18h 32m

Santiago Arturo Merino Benitez

Thu 5/14

12:38 am-6:25 pm

1 stop19h 47m

$753

Quickest round-trip

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 5/19

11:25 am-5:35 am

2 stops16h 10m

Santiago Arturo Merino Benitez

Sun 5/24

11:25 pm-5:35 pm

1 stop20h 10m

$767

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 5/19

7:20 am-5:35 am

2 stops20h 15m

Santiago Arturo Merino Benitez

Sun 5/24

11:05 pm-5:57 pm

2 stops20h 52m

$784

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 4/6

6:30 am-5:35 am

1 stop21h 05m

Santiago Arturo Merino Benitez

Mon 4/13

11:00 pm-8:19 pm

2 stops23h 19m

$791

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 5/18

7:20 am-7:15 am

1 stop21h 55m

Santiago Arturo Merino Benitez

Sat 5/23

8:40 pm-11:18 am

1 stop16h 38m

$795

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 4/21

11:05 pm-5:35 am

1 stop28h 30m

Santiago Arturo Merino Benitez

Tue 4/28

5:00 am-9:40 am

2 stops30h 40m

$800

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $663. If you don’t want to visit Santiago in September, then you should wait until October to fly from Denver, when ticket prices are also cheap, with an average price of $681.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $798 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $618 on momondo.

Can stopping save me money on Denver to Santiago flights?

You could potentially save up to 2% on your flight if you consider stops on a Denver to Santiago flight.

How have Denver to Santiago flight prices changed over time?

As of March 2026, prices for Denver to Santiago flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time	14h 10m
Direct flights	None

The fastest flight from Denver to Santiago takes 14h 10m

There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

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How far is Denver Intl to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 14h 10m is a normal flight duration for this route.
When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
As of March 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Denver to Santiago?
Based on momondo bookings for flights between Denver and Santiago, the leading airline is American Airlines, making up 26% of the total bookings. Other popular airlines include Delta with 24%, United Airlines with 20%, and LATAM Airlines with 19%.

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $369	Free Cancellation	Rating 7.5 1,569 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $537	Free Cancellation	Rating 7.4 1,918 reviews	Search LATAM Airlines flights
Delta	PriceFrom $544	Free Cancellation	Rating 7.9 8,276 reviews	Search Delta flights
United Airlines	PriceFrom $551	Free Cancellation	Rating 7.4 9,409 reviews	Search United Airlines flights
American Airlines	PriceFrom $608	Free Cancellation	Rating 7.1 11,409 reviews	Search American Airlines flights
Aeromexico	PriceFrom $823	Free Cancellation	Rating 7.4 1,569 reviews	Search Aeromexico flights

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Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.