Which layover airport has the shortest connection time from Denver to Santiago?

Dallas (DFW) has the shortest average layover time for this route: 1h 47m.

What airlines fly to Santiago?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Santiago from Denver according to our data. American Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 6 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Denver to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 13h 01m.

Which layover airport offers the lowest fares from Denver to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $625.

Which airport is the most popular layover for flights between Denver and Santiago?

Houston (IAH) was the most common stop: 69% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

As of February 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$224 Cheap Flights from Denver to Santiago in 2026

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Find the cheapest flights from Denver to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:05 pm - 9:05 pm

DEN

SCL

20h 00m

2 stops

10:30 am - 10:30 am

SCL

DEN

26h 00m

1 stop

$545Multiple Airlines

dom., abr. 19 - mar., abr. 28

11:05 pm - 9:05 pm

DEN

SCL

20h 00m

2 stops

10:30 am - 10:30 am

SCL

DEN

26h 00m

1 stop

$558Multiple Airlines

sáb., abr. 18 - mar., abr. 28

12:00 pm - 6:55 am

DEN

SCL

16h 55m

2 stops

11:25 pm - 6:10 pm

SCL

DEN

20h 45m

1 stop

$567LATAM Airlines

lun., ago. 10 - lun., ago. 24

9:35 am - 7:15 am

DEN

SCL

19h 40m

1 stop

11:25 pm - 6:10 pm

SCL

DEN

20h 45m

1 stop

$573LATAM Airlines

dom., ago. 9 - jue., ago. 20

12:00 pm - 6:55 am

DEN

SCL

16h 55m

2 stops

5:40 am - 11:45 pm

SCL

DEN

20h 05m

2 stops

$578LATAM Airlines

mié., ago. 12 - mié., ago. 26

12:00 pm - 5:35 am

DEN

SCL

15h 35m

2 stops

7:45 am - 11:51 pm

SCL

DEN

18h 06m

2 stops

$581LATAM Airlines

mié., may. 13 - mié., may. 20

9:35 am - 6:00 am

DEN

SCL

18h 25m

2 stops

11:05 pm - 11:45 pm

SCL

DEN

26h 40m

2 stops

$585LATAM Airlines

mar., jun. 16 - jue., jul. 9

7:05 am - 7:15 am

DEN

SCL

22h 10m

1 stop

7:45 pm - 2:05 pm

SCL

DEN

20h 20m

2 stops

$587LATAM Airlines

mar., jun. 16 - vie., jul. 3

10:45 am - 5:35 am

DEN

SCL

16h 50m

2 stops

10:30 am - 10:54 am

SCL

DEN

26h 24m

2 stops

$590LATAM Airlines

dom., ago. 9 - dom., ago. 16

7:05 am - 4:50 am

DEN

SCL

19h 45m

2 stops

9:25 pm - 11:30 am

SCL

DEN

40h 05m

2 stops

$593LATAM Airlines

mié., jun. 17 - lun., jul. 6

Delta flights from Denver to Santiago

Our best Delta deals on Denver to Santiago flight tickets

Delta

Aug 9

DEN1:35 pmDenver Intl

15h 40m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Aug 20

SCL8:40 pmSantiago Arturo Merino Benitez

23h 18m

1 stop

DEN5:58 pmDenver Intl

$585

Delta

Jun 25

DEN10:45 amDenver Intl

18h 30m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Jul 15

SCL8:40 pmSantiago Arturo Merino Benitez

29h 05m

1 stop

DEN11:45 pmDenver Intl

$594

Delta

Jun 22

DEN12:59 amDenver Intl

27h 56m

2 stops

SCL6:55 amSantiago Arturo Merino Benitez

Jul 16

SCL8:40 pmSantiago Arturo Merino Benitez

27h 34m

1 stop

DEN10:14 pmDenver Intl

$599

American Airlines flights from Denver to Santiago

Our best American Airlines deals on Denver to Santiago flight tickets

American Airlines

Aug 9

DEN7:20 amDenver Intl

21h 30m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Aug 20

SCL8:30 pmSantiago Arturo Merino Benitez

17h 11m

2 stops

DEN11:41 amDenver Intl

$590

American Airlines

Mar 26

DEN12:33 pmDenver Intl

17h 32m

1 stop

SCL9:05 amSantiago Arturo Merino Benitez

Apr 17

SCL8:35 pmSantiago Arturo Merino Benitez

17h 12m

1 stop

DEN11:47 amDenver Intl

$750

American Airlines

Feb 28

DEN12:33 pmDenver Intl

16h 57m

2 stops

SCL9:30 amSantiago Arturo Merino Benitez

Mar 8

SCL9:20 pmSantiago Arturo Merino Benitez

19h 37m

2 stops

DEN1:57 pmDenver Intl

$1,192

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

dom. 4/19

11:05 pm-9:05 pm

2 stops20h 00m

Santiago Arturo Merino Benitez

mar. 4/28

10:30 am-10:30 am

1 stop26h 00m

$545

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

sáb. 4/18

11:05 pm-9:05 pm

2 stops20h 00m

Santiago Arturo Merino Benitez

mar. 4/28

10:30 am-10:30 am

1 stop26h 00m

$558

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 8/10

12:00 pm-6:55 am

2 stops16h 55m

Santiago Arturo Merino Benitez

lun. 8/24

11:25 pm-6:10 pm

1 stop20h 45m

$567

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

dom. 8/9

9:35 am-7:15 am

1 stop19h 40m

Santiago Arturo Merino Benitez

jue. 8/20

11:25 pm-6:10 pm

1 stop20h 45m

$573

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

mié. 8/12

12:00 pm-6:55 am

2 stops16h 55m

Santiago Arturo Merino Benitez

mié. 8/26

5:40 am-11:45 pm

2 stops20h 05m

$578

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

mié. 5/13

12:00 pm-5:35 am

2 stops15h 35m

Santiago Arturo Merino Benitez

mié. 5/20

7:45 am-11:51 pm

2 stops18h 06m

$581

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

mar. 6/16

9:35 am-6:00 am

2 stops18h 25m

Santiago Arturo Merino Benitez

jue. 7/9

11:05 pm-11:45 pm

2 stops26h 40m

$585

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

mar. 6/16

7:05 am-7:15 am

1 stop22h 10m

Santiago Arturo Merino Benitez

vie. 7/3

7:45 pm-2:05 pm

2 stops20h 20m

$587

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

dom. 8/9

10:45 am-5:35 am

2 stops16h 50m

Santiago Arturo Merino Benitez

dom. 8/16

10:30 am-10:54 am

2 stops26h 24m

$590

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

mié. 6/17

7:05 am-4:50 am

2 stops19h 45m

Santiago Arturo Merino Benitez

lun. 7/6

9:25 pm-11:30 am

2 stops40h 05m

$593

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Santiago?

In general, April is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $638. If you don’t want to visit Santiago in April, then you should wait until September to fly from Denver, when ticket prices are also cheap, with an average price of $663.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $794 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $611 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time	12h 55m
Direct flights	None

The fastest flight from Denver to Santiago takes 12h 55m

There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

Search flight deals

How far is Denver Intl to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 12h 55m is a normal flight duration for this route.
When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
As of February 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Denver to Santiago?
Based on momondo bookings for flights between Denver and Santiago, the leading airline is American Airlines, making up 29% of the total bookings. Other popular airlines include Delta with 22%, United Airlines with 20%, and LATAM Airlines with 17%.

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $369	Free Cancellation	Rating 7.5 1,559 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $537	Free Cancellation	Rating 7.5 1,920 reviews	Search LATAM Airlines flights
Delta	PriceFrom $544	Free Cancellation	Rating 7.9 8,200 reviews	Search Delta flights
United Airlines	PriceFrom $551	Free Cancellation	Rating 7.4 9,289 reviews	Search United Airlines flights
American Airlines	PriceFrom $613	Free Cancellation	Rating 7.2 11,288 reviews	Search American Airlines flights
Aeromexico	PriceFrom $823	Free Cancellation	Rating 7.4 1,578 reviews	Search Aeromexico flights

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Santa Cruz

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San Fernando

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Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.