Which layover airport offers the lowest fares from Denver to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $625.

Which airport is the most popular layover for flights between Denver and Santiago?

Houston (IAH) was the most common stop: 69% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to Santiago?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to Santiago from Denver according to our data. American Airlines is the first choice among our users, with 35% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 6 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Denver to Santiago?

Dallas (DFW) has the shortest average layover time for this route: 1h 47m.

Which layover airport has the shortest travel time from Denver to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 13h 01m.

When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

As of January 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$259 Cheap Flights from Denver to Santiago in 2026

Q: What is the typical price of a round-trip flight between Denver and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $669 to $970. The lowest price recently found on this route was $543.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Denver to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:44 pm - 6:50 am

DEN

SCL

16h 06m

1 stop

10:55 pm - 7:42 pm

SCL

DEN

22h 47m

1 stop

$543LATAM Airlines

Thu, Apr 23 - Sat, May 2

11:43 am - 7:15 am

DEN

SCL

17h 32m

1 stop

10:55 pm - 10:49 pm

SCL

DEN

25h 54m

1 stop

$565Delta

Fri, Apr 24 - Sat, May 2

12:55 am - 6:00 am

DEN

SCL

27h 05m

2 stops

11:00 pm - 12:26 am

SCL

DEN

27h 26m

2 stops

$570LATAM Airlines

Thu, Apr 23 - Sat, May 2

7:00 am - 1:35 pm

DEN

SCL

28h 35m

2 stops

11:25 pm - 11:37 pm

SCL

DEN

26h 12m

1 stop

$573Multiple Airlines

Thu, Apr 23 - Sat, May 2

12:33 pm - 6:50 am

DEN

SCL

16h 17m

1 stop

8:30 pm - 11:32 pm

SCL

DEN

29h 02m

1 stop

$630American Airlines

Mon, Apr 20 - Mon, Apr 27

7:26 am - 6:50 am

DEN

SCL

21h 24m

2 stops

8:30 pm - 11:32 pm

SCL

DEN

29h 02m

1 stop

$635American Airlines

Mon, Apr 20 - Mon, Apr 27

6:30 am - 5:35 am

DEN

SCL

20h 05m

1 stop

11:55 pm - 6:00 pm

SCL

DEN

21h 05m

1 stop

$647LATAM Airlines

Wed, Mar 18 - Wed, Mar 25

9:35 am - 7:15 am

DEN

SCL

17h 40m

1 stop

8:40 pm - 11:45 pm

SCL

DEN

30h 05m

1 stop

$659LATAM Airlines

Sun, Mar 1 - Sun, Mar 8

6:30 am - 5:35 am

DEN

SCL

20h 05m

1 stop

5:15 am - 12:09 am

SCL

DEN

21h 54m

2 stops

$661LATAM Airlines

Wed, Mar 18 - Wed, Mar 25

1:25 pm - 5:25 pm

DEN

SCL

26h 00m

2 stops

11:00 pm - 12:26 am

SCL

DEN

27h 26m

2 stops

$670LATAM Airlines

Thu, Apr 23 - Sat, May 2

American Airlines flights from Denver to Santiago

Our best American Airlines deals on Denver to Santiago flight tickets

American Airlines

Apr 20

DEN12:33 pmDenver Intl

16h 17m

1 stop

SCL6:50 amSantiago Arturo Merino Benitez

Apr 27

SCL8:30 pmSantiago Arturo Merino Benitez

29h 02m

1 stop

DEN11:32 pmDenver Intl

$630

American Airlines

Apr 20

DEN7:26 amDenver Intl

21h 24m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Apr 27

SCL8:30 pmSantiago Arturo Merino Benitez

29h 02m

1 stop

DEN11:32 pmDenver Intl

$635

American Airlines

Mar 11

DEN10:20 amDenver Intl

17h 40m

1 stop

SCL7:00 amSantiago Arturo Merino Benitez

Mar 17

SCL9:20 pmSantiago Arturo Merino Benitez

21h 33m

2 stops

DEN3:53 pmDenver Intl

$740

United Airlines flights from Denver to Santiago

Our best United Airlines deals on Denver to Santiago flight tickets

United Airlines

Mar 11

DEN1:25 pmDenver Intl

15h 25m

1 stop

SCL7:50 amSantiago Arturo Merino Benitez

Mar 17

SCL9:45 pmSantiago Arturo Merino Benitez

15h 15m

1 stop

DEN10:00 amDenver Intl

$735

United Airlines

Feb 20

DEN8:33 pmDenver Intl

32h 17m

1 stop

SCL8:50 amSantiago Arturo Merino Benitez

Mar 15

SCL9:45 pmSantiago Arturo Merino Benitez

13h 35m

1 stop

DEN8:20 amDenver Intl

$770

United Airlines

Feb 22

DEN8:33 pmDenver Intl

32h 17m

1 stop

SCL8:50 amSantiago Arturo Merino Benitez

Mar 20

SCL9:45 pmSantiago Arturo Merino Benitez

13h 35m

1 stop

DEN8:20 amDenver Intl

$772

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 4/23

12:44 pm-6:50 am

1 stop16h 06m

Santiago Arturo Merino Benitez

Sat 5/2

10:55 pm-7:42 pm

1 stop22h 47m

$543

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 4/24

11:43 am-7:15 am

1 stop17h 32m

Santiago Arturo Merino Benitez

Sat 5/2

10:55 pm-10:49 pm

1 stop25h 54m

$565

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 4/23

12:55 am-6:00 am

2 stops27h 05m

Santiago Arturo Merino Benitez

Sat 5/2

11:00 pm-12:26 am

2 stops27h 26m

$570

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 4/23

7:00 am-1:35 pm

2 stops28h 35m

Santiago Arturo Merino Benitez

Sat 5/2

11:25 pm-11:37 pm

1 stop26h 12m

$573

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 4/20

12:33 pm-6:50 am

1 stop16h 17m

Santiago Arturo Merino Benitez

Mon 4/27

8:30 pm-11:32 pm

1 stop29h 02m

$630

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 4/20

7:26 am-6:50 am

2 stops21h 24m

Santiago Arturo Merino Benitez

Mon 4/27

8:30 pm-11:32 pm

1 stop29h 02m

$635

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 3/18

6:30 am-5:35 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Wed 3/25

11:55 pm-6:00 pm

1 stop21h 05m

$647

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/1

9:35 am-7:15 am

1 stop17h 40m

Santiago Arturo Merino Benitez

Sun 3/8

8:40 pm-11:45 pm

1 stop30h 05m

$659

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 3/18

6:30 am-5:35 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Wed 3/25

5:15 am-12:09 am

2 stops21h 54m

$661

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 4/23

1:25 pm-5:25 pm

2 stops26h 00m

Santiago Arturo Merino Benitez

Sat 5/2

11:00 pm-12:26 am

2 stops27h 26m

$670

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Denver and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $663. If you don’t want to visit Santiago in September, then you should wait until April to fly from Denver, when ticket prices are also cheap, with an average price of $732.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $813 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $608 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time	16h 06m
Direct flights	None

The fastest flight from Denver to Santiago takes 16h 06m

There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

Search flight deals

How far is Denver Intl to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 16h 06m is a normal flight duration for this route.
When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
As of January 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Denver to Santiago?
Based on momondo bookings for flights between Denver and Santiago, the leading airline is American Airlines, making up 31% of the total bookings. Other popular airlines include Delta with 22%, LATAM Airlines with 18%, and United Airlines with 18%.

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $369	Free Cancellation	Rating 7.6 1,558 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $537	Free Cancellation	Rating 7.5 1,914 reviews	Search LATAM Airlines flights
Delta	PriceFrom $544	Free Cancellation	Rating 7.9 8,113 reviews	Search Delta flights
United Airlines	PriceFrom $551	Free Cancellation	Rating 7.4 9,196 reviews	Search United Airlines flights
American Airlines	PriceFrom $613	Free Cancellation	Rating 7.2 11,194 reviews	Search American Airlines flights
Aeromexico	PriceFrom $823	Free Cancellation	Rating 7.4 1,591 reviews	Search Aeromexico flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.