Which airport is the most popular layover for flights between Denver and Santiago?

Houston (IAH) was the most common stop: 69% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to Santiago?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Santiago from Denver according to our data. American Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 6 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport offers the lowest fares from Denver to Santiago?

Flights via Dallas (DFW) offer the lowest average round-trip price of $625.

Which layover airport has the shortest connection time from Denver to Santiago?

Dallas (DFW) has the shortest average layover time for this route: 1h 47m.

Which layover airport has the shortest travel time from Denver to Santiago?

Flights connecting via Dallas (DFW) have the shortest average one-way travel time: 13h 01m.

When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

As of March 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$225 Cheap Flights from Denver to Santiago in 2026

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7:05 am - 5:35 am

DEN

SCL

20h 30m

2 stops

7:45 am - 11:45 pm

SCL

DEN

19h 00m

2 stops

$578LATAM Airlines

Tue, Sep 1 - Wed, Sep 30

1:35 pm - 7:15 am

DEN

SCL

15h 40m

1 stop

8:40 pm - 11:41 am

SCL

DEN

18h 01m

1 stop

$583LATAM Airlines

Tue, Sep 1 - Wed, Sep 30

12:00 pm - 7:15 am

DEN

SCL

17h 15m

1 stop

11:05 pm - 11:45 pm

SCL

DEN

26h 40m

2 stops

$585LATAM Airlines

Sun, Aug 9 - Thu, Aug 20

9:48 am - 6:50 am

DEN

SCL

19h 02m

2 stops

8:30 pm - 11:51 am

SCL

DEN

17h 21m

2 stops

$587American Airlines

Wed, Aug 5 - Wed, Aug 12

10:32 am - 6:50 am

DEN

SCL

18h 18m

2 stops

8:30 pm - 1:24 pm

SCL

DEN

18h 54m

2 stops

$590American Airlines

Mon, Aug 3 - Mon, Aug 31

11:05 pm - 5:30 am

DEN

SCL

28h 25m

2 stops

10:30 am - 9:40 am

SCL

DEN

25h 10m

1 stop

$599Multiple Airlines

Wed, Apr 15 - Wed, Apr 22

11:05 pm - 9:05 pm

DEN

SCL

20h 00m

2 stops

8:40 am - 9:40 am

SCL

DEN

27h 00m

2 stops

$605Multiple Airlines

Fri, Apr 17 - Fri, Apr 24

12:00 pm - 6:55 am

DEN

SCL

16h 55m

2 stops

11:25 pm - 6:10 pm

SCL

DEN

20h 45m

1 stop

$614LATAM Airlines

Sun, Aug 9 - Thu, Aug 20

11:05 pm - 11:05 am

DEN

SCL

34h 00m

3 stops

8:40 am - 9:40 am

SCL

DEN

27h 00m

2 stops

$616Multiple Airlines

Fri, Apr 17 - Fri, Apr 24

9:35 am - 7:15 am

DEN

SCL

19h 40m

1 stop

11:25 pm - 6:10 pm

SCL

DEN

20h 45m

1 stop

$620LATAM Airlines

Wed, Aug 5 - Wed, Aug 12

LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets

LATAM Airlines

Sep 1

DEN7:05 amDenver Intl

20h 30m

2 stops

SCL5:35 amSantiago Arturo Merino Benitez

Sep 30

SCL7:45 amSantiago Arturo Merino Benitez

19h 00m

2 stops

DEN11:45 pmDenver Intl

$578

LATAM Airlines

Sep 1

DEN7:05 amDenver Intl

22h 10m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Sep 28

SCL8:40 pmSantiago Arturo Merino Benitez

18h 01m

1 stop

DEN11:41 amDenver Intl

$583

LATAM Airlines

Aug 12

DEN9:35 amDenver Intl

19h 40m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Aug 24

SCL8:40 pmSantiago Arturo Merino Benitez

16h 14m

1 stop

DEN10:54 amDenver Intl

$585

American Airlines flights from Denver to Santiago

Our best American Airlines deals on Denver to Santiago flight tickets

American Airlines

Aug 5

DEN9:48 amDenver Intl

19h 02m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Aug 12

SCL8:30 pmSantiago Arturo Merino Benitez

17h 21m

2 stops

DEN11:51 amDenver Intl

$587

American Airlines

Aug 3

DEN10:32 amDenver Intl

18h 18m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Aug 31

SCL8:30 pmSantiago Arturo Merino Benitez

18h 54m

2 stops

DEN1:24 pmDenver Intl

$590

American Airlines

Aug 5

DEN10:38 amDenver Intl

18h 12m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Aug 12

SCL8:30 pmSantiago Arturo Merino Benitez

18h 54m

2 stops

DEN1:24 pmDenver Intl

$641

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 9/1

7:05 am-5:35 am

2 stops20h 30m

Santiago Arturo Merino Benitez

Wed 9/30

7:45 am-11:45 pm

2 stops19h 00m

$578

Quickest round-trip

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 9/1

1:35 pm-7:15 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Wed 9/30

8:40 pm-11:41 am

1 stop18h 01m

$583

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 8/9

12:00 pm-7:15 am

1 stop17h 15m

Santiago Arturo Merino Benitez

Thu 8/20

11:05 pm-11:45 pm

2 stops26h 40m

$585

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 8/5

9:48 am-6:50 am

2 stops19h 02m

Santiago Arturo Merino Benitez

Wed 8/12

8:30 pm-11:51 am

2 stops17h 21m

$587

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 8/3

10:32 am-6:50 am

2 stops18h 18m

Santiago Arturo Merino Benitez

Mon 8/31

8:30 pm-1:24 pm

2 stops18h 54m

$590

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 4/15

11:05 pm-5:30 am

2 stops28h 25m

Santiago Arturo Merino Benitez

Wed 4/22

10:30 am-9:40 am

1 stop25h 10m

$599

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 4/17

11:05 pm-9:05 pm

2 stops20h 00m

Santiago Arturo Merino Benitez

Fri 4/24

8:40 am-9:40 am

2 stops27h 00m

$605

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 8/9

12:00 pm-6:55 am

2 stops16h 55m

Santiago Arturo Merino Benitez

Thu 8/20

11:25 pm-6:10 pm

1 stop20h 45m

$614

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 4/17

11:05 pm-11:05 am

3 stops34h 00m

Santiago Arturo Merino Benitez

Fri 4/24

8:40 am-9:40 am

2 stops27h 00m

$616

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 8/5

9:35 am-7:15 am

1 stop19h 40m

Santiago Arturo Merino Benitez

Wed 8/12

11:25 pm-6:10 pm

1 stop20h 45m

$620

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $663. If you don’t want to visit Santiago in September, then you should wait until October to fly from Denver, when ticket prices are also cheap, with an average price of $681.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $798 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $618 on momondo.

Can stopping save me money on Denver to Santiago flights?

You could potentially save up to 2% on your flight if you consider stops on a Denver to Santiago flight.

How have Denver to Santiago flight prices changed over time?

As of March 2026, prices for Denver to Santiago flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time	14h 05m
Direct flights	None

The fastest flight from Denver to Santiago takes 14h 05m

There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

Search flight deals

How far is Denver Intl to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 14h 05m is a normal flight duration for this route.
When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
As of March 2026, there are 6 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Denver to Santiago?
Based on momondo bookings for flights between Denver and Santiago, the leading airline is American Airlines, making up 27% of the total bookings. Other popular airlines include Delta with 24%, United Airlines with 19%, and LATAM Airlines with 18%.

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $369	Free Cancellation	Rating 7.5 1,565 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $537	Free Cancellation	Rating 7.4 1,917 reviews	Search LATAM Airlines flights
Delta	PriceFrom $544	Free Cancellation	Rating 7.9 8,270 reviews	Search Delta flights
United Airlines	PriceFrom $551	Free Cancellation	Rating 7.4 9,405 reviews	Search United Airlines flights
American Airlines	PriceFrom $608	Free Cancellation	Rating 7.1 11,397 reviews	Search American Airlines flights
Aeromexico	PriceFrom $823	Free Cancellation	Rating 7.4 1,570 reviews	Search Aeromexico flights

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Santa Cruz

Valle Nevado

San Fernando

Pichilemu

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Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.