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Cheap flights from Denver to Santiago from $210

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Santiago departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
LATAM Airlines Logo
1:15 pm - 6:55 amDEN-SCL
15h 40m2 stops
LATAM Airlines Logo
11:00 pm - 6:03 pmSCL-DEN
21h 03m2 stops
$528LATAM Airlines
Find Deal
Tue, Apr 7 - Tue, Apr 21
LATAM Airlines Logo
10:31 am - 5:35 amDEN-SCL
16h 04m2 stops
LATAM Airlines Logo
11:00 pm - 8:14 pmSCL-DEN
24h 14m2 stops
$529LATAM Airlines
Find Deal
Thu, Mar 19 - Mon, Mar 30
LATAM Airlines Logo
3:05 pm - 7:40 amDEN-SCL
13h 35m1 stop
LATAM Airlines Logo
11:00 pm - 8:14 pmSCL-DEN
23h 14m2 stops
$530LATAM Airlines
Find Deal
Mon, Mar 23 - Mon, Apr 6
LATAM Airlines Logo
10:50 am - 7:40 amDEN-SCL
16h 50m1 stop
LATAM Airlines Logo
11:55 pm - 6:00 pmSCL-DEN
21h 05m1 stop
$531LATAM Airlines
Find Deal
Sun, Mar 1 - Sun, Mar 8
LATAM Airlines Logo
1:12 pm - 7:40 amDEN-SCL
14h 28m1 stop
LATAM Airlines Logo
11:55 pm - 6:00 pmSCL-DEN
21h 05m1 stop
$533LATAM Airlines
Find Deal
Sun, Mar 1 - Sun, Mar 8
Delta Logo
3:10 pm - 2:05 pmDEN-SCL
20h 55m2 stops
Delta Logo
8:40 pm - 11:51 pmSCL-DEN
29h 11m1 stop
$535Delta
Find Deal
Tue, May 26 - Mon, Jun 8
Delta Logo
4:40 pm - 2:05 pmDEN-SCL
19h 25m2 stops
Delta Logo
8:40 pm - 11:51 pmSCL-DEN
29h 11m1 stop
$536Delta
Find Deal
Tue, May 26 - Tue, Jun 9
Delta Logo
6:00 am - 7:40 amDEN-SCL
22h 40m1 stop
Delta Logo
7:45 am - 12:09 amSCL-DEN
18h 24m2 stops
$537Delta
Find Deal
Thu, Mar 26 - Thu, Apr 9
LATAM Airlines Logo
1:15 pm - 7:40 amDEN-SCL
15h 25m1 stop
LATAM Airlines Logo
11:00 pm - 6:03 pmSCL-DEN
21h 03m2 stops
$538LATAM Airlines
Find Deal
Mon, Mar 16 - Mon, May 4
LATAM Airlines Logo
1:15 pm - 7:40 amDEN-SCL
15h 25m1 stop
LATAM Airlines Logo
11:00 pm - 8:14 pmSCL-DEN
24h 14m2 stops
$540LATAM Airlines
Find Deal
Thu, Mar 19 - Mon, Mar 30

LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets
LATAM Airlines
Apr 7
DEN1:15 pmDenver Intl
15h 40m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
Apr 21
SCL11:00 pmSantiago Arturo Merino Benitez
21h 03m
2 stops
DEN6:03 pmDenver Intl
$528
Find similar
LATAM Airlines
Mar 19
DEN10:31 amDenver Intl
16h 04m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Mar 30
SCL11:00 pmSantiago Arturo Merino Benitez
24h 14m
2 stops
DEN8:14 pmDenver Intl
$529
Find similar
LATAM Airlines
Mar 23
DEN3:05 pmDenver Intl
13h 35m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Apr 6
SCL11:00 pmSantiago Arturo Merino Benitez
23h 14m
2 stops
DEN8:14 pmDenver Intl
$530
Find similar

Delta flights from Denver to Santiago

Our best Delta deals on Denver to Santiago flight tickets
Delta
Mar 26
DEN1:15 pmDenver Intl
15h 25m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Apr 8
SCL8:40 pmSantiago Arturo Merino Benitez
20h 42m
1 stop
DEN3:22 pmDenver Intl
$535
Find similar
Delta
May 26
DEN12:59 amDenver Intl
28h 01m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Jun 7
SCL8:40 pmSantiago Arturo Merino Benitez
27h 38m
1 stop
DEN10:18 pmDenver Intl
$536
Find similar
Delta
Mar 26
DEN6:00 amDenver Intl
20h 35m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Apr 9
SCL7:45 amSantiago Arturo Merino Benitez
18h 24m
2 stops
DEN12:09 amDenver Intl
$537
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 2, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 4/7

1:15 pm-6:55 am

2 stops15h 40m

Santiago Arturo Merino Benitez

Tue 4/21

11:00 pm-6:03 pm

2 stops21h 03m

$528

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 3/19

10:31 am-5:35 am

2 stops16h 04m

Santiago Arturo Merino Benitez

Mon 3/30

11:00 pm-8:14 pm

2 stops24h 14m

$529

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 3/23

3:05 pm-7:40 am

1 stop13h 35m

Santiago Arturo Merino Benitez

Mon 4/6

11:00 pm-8:14 pm

2 stops23h 14m

$530

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/1

10:50 am-7:40 am

1 stop16h 50m

Santiago Arturo Merino Benitez

Sun 3/8

11:55 pm-6:00 pm

1 stop21h 05m

$531

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/1

1:12 pm-7:40 am

1 stop14h 28m

Santiago Arturo Merino Benitez

Sun 3/8

11:55 pm-6:00 pm

1 stop21h 05m

$533

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 5/26

3:10 pm-2:05 pm

2 stops20h 55m

Santiago Arturo Merino Benitez

Mon 6/8

8:40 pm-11:51 pm

1 stop29h 11m

$535

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 5/26

4:40 pm-2:05 pm

2 stops19h 25m

Santiago Arturo Merino Benitez

Tue 6/9

8:40 pm-11:51 pm

1 stop29h 11m

$536

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 3/26

6:00 am-7:40 am

1 stop22h 40m

Santiago Arturo Merino Benitez

Thu 4/9

7:45 am-12:09 am

2 stops18h 24m

$537

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 3/16

1:15 pm-7:40 am

1 stop15h 25m

Santiago Arturo Merino Benitez

Mon 5/4

11:00 pm-6:03 pm

2 stops21h 03m

$538

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 3/19

1:15 pm-7:40 am

1 stop15h 25m

Santiago Arturo Merino Benitez

Mon 3/30

11:00 pm-8:14 pm

2 stops24h 14m

$540

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $681. If you don’t want to visit Santiago in September, then you should wait until October to fly from Denver, when ticket prices are also cheap, with an average price of $728.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $798. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,032.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Denver to Santiago when you can find flight prices for as low as $827. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $985 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $827 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $733 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time

13h 45m

Direct flights

None
The fastest flight from Denver to Santiago takes 13h 45m
There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.
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  • How far is Denver Intl to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 13h 35m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Denver to Santiago?

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $551Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $562Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $575Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
DeltaPriceFrom $623Free CancellationRating
7.9
8,011 reviews
Search Delta flights
American AirlinesPriceFrom $625Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights
AeromexicoPriceFrom $823Free CancellationRating
7.4
1,653 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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