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Cheap flights from Denver to Santiago from $257

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Santiago departing on 1/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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LATAM Airlines Logo
7:05 am - 5:35 amDEN-SCL
19h 30m2 stops
LATAM Airlines Logo
11:00 pm - 8:14 pmSCL-DEN
24h 14m2 stops
$529LATAM Airlines
Find Deal
Thu, Mar 19 - Mon, Mar 30
LATAM Airlines Logo
12:00 pm - 7:40 amDEN-SCL
15h 40m1 stop
LATAM Airlines Logo
11:55 pm - 6:00 pmSCL-DEN
21h 05m1 stop
$532LATAM Airlines
Find Deal
Sun, Mar 1 - Sun, Mar 8
Delta Logo
6:00 am - 6:55 amDEN-SCL
20h 55m1 stop
Delta Logo
10:10 pm - 11:54 amSCL-DEN
16h 44m1 stop
$534Delta
Find Deal
Sun, Mar 1 - Mon, Mar 16
Delta Logo
7:05 am - 5:35 amDEN-SCL
18h 30m2 stops
Delta Logo
11:25 pm - 3:22 pmSCL-DEN
18h 57m2 stops
$535Delta
Find Deal
Wed, Mar 4 - Tue, Mar 10
Delta Logo
7:05 am - 5:35 amDEN-SCL
18h 30m2 stops
Delta Logo
11:25 pm - 3:22 pmSCL-DEN
18h 57m2 stops
$536Delta
Find Deal
Wed, Mar 4 - Wed, Mar 11
Delta Logo
7:05 am - 5:35 amDEN-SCL
18h 30m2 stops
Delta Logo
11:25 pm - 3:22 pmSCL-DEN
18h 57m2 stops
$537Delta
Find Deal
Wed, Mar 4 - Mon, Mar 16
LATAM Airlines Logo
3:05 pm - 7:40 amDEN-SCL
13h 35m1 stop
LATAM Airlines Logo
11:00 pm - 8:14 pmSCL-DEN
23h 14m2 stops
$538LATAM Airlines
Find Deal
Mon, Mar 23 - Mon, Apr 6
LATAM Airlines Logo
1:15 pm - 7:40 amDEN-SCL
15h 25m1 stop
LATAM Airlines Logo
11:00 pm - 8:14 pmSCL-DEN
24h 14m2 stops
$540LATAM Airlines
Find Deal
Thu, Mar 19 - Mon, Mar 30
United Airlines Logo
4:30 pm - 8:50 amDEN-SCL
12h 20m1 stop
United Airlines Logo
9:45 pm - 8:20 amSCL-DEN
13h 35m1 stop
$544United Airlines
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Tue, Mar 3 - Wed, Mar 11
LATAM Airlines Logo
7:05 am - 7:00 amDEN-SCL
19h 55m2 stops
LATAM Airlines Logo
10:10 pm - 8:14 pmSCL-DEN
25h 04m1 stop
$547LATAM Airlines
Find Deal
Thu, Mar 5 - Fri, Mar 13

LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets
LATAM Airlines
Mar 19
DEN7:05 amDenver Intl
19h 30m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Mar 30
SCL11:00 pmSantiago Arturo Merino Benitez
24h 14m
2 stops
DEN8:14 pmDenver Intl
$529
Find similar
LATAM Airlines
Mar 1
DEN12:00 pmDenver Intl
15h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Mar 8
SCL11:55 pmSantiago Arturo Merino Benitez
21h 05m
1 stop
DEN6:00 pmDenver Intl
$532
Find similar
LATAM Airlines
Mar 23
DEN3:05 pmDenver Intl
13h 35m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Apr 6
SCL11:00 pmSantiago Arturo Merino Benitez
23h 14m
2 stops
DEN8:14 pmDenver Intl
$538
Find similar

American Airlines flights from Denver to Santiago

Our best American Airlines deals on Denver to Santiago flight tickets
American Airlines
Feb 10
DEN8:44 amDenver Intl
19h 31m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Feb 24
SCL11:15 pmSantiago Arturo Merino Benitez
16h 24m
1 stop
DEN11:39 amDenver Intl
$599
Find similar
American Airlines
Feb 9
DEN6:00 amDenver Intl
22h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Feb 23
SCL10:25 pmSantiago Arturo Merino Benitez
19h 31m
2 stops
DEN1:56 pmDenver Intl
$604
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 3/19

7:05 am-5:35 am

2 stops19h 30m

Santiago Arturo Merino Benitez

Mon 3/30

11:00 pm-8:14 pm

2 stops24h 14m

$529

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/1

12:00 pm-7:40 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Sun 3/8

11:55 pm-6:00 pm

1 stop21h 05m

$532

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 3/1

6:00 am-6:55 am

1 stop20h 55m

Santiago Arturo Merino Benitez

Mon 3/16

10:10 pm-11:54 am

1 stop16h 44m

$534

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 3/4

7:05 am-5:35 am

2 stops18h 30m

Santiago Arturo Merino Benitez

Tue 3/10

11:25 pm-3:22 pm

2 stops18h 57m

$535

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 3/4

7:05 am-5:35 am

2 stops18h 30m

Santiago Arturo Merino Benitez

Wed 3/11

11:25 pm-3:22 pm

2 stops18h 57m

$536

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Wed 3/4

7:05 am-5:35 am

2 stops18h 30m

Santiago Arturo Merino Benitez

Mon 3/16

11:25 pm-3:22 pm

2 stops18h 57m

$537

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 3/23

3:05 pm-7:40 am

1 stop13h 35m

Santiago Arturo Merino Benitez

Mon 4/6

11:00 pm-8:14 pm

2 stops23h 14m

$538

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 3/19

1:15 pm-7:40 am

1 stop15h 25m

Santiago Arturo Merino Benitez

Mon 3/30

11:00 pm-8:14 pm

2 stops24h 14m

$540

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 3/3

4:30 pm-8:50 am

1 stop12h 20m

Santiago Arturo Merino Benitez

Wed 3/11

9:45 pm-8:20 am

1 stop13h 35m

$544

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 3/5

7:05 am-7:00 am

2 stops19h 55m

Santiago Arturo Merino Benitez

Fri 3/13

10:10 pm-8:14 pm

1 stop25h 04m

$547

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $681. If you don’t want to visit Santiago in September, then you should wait until October to fly from Denver, when ticket prices are also cheap, with an average price of $728.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $798. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,032.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Denver to Santiago when you can find flight prices for as low as $827. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $985 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $827 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $733 on momondo.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Fastest flight time

15h 20m

Direct flights

None
The fastest flight from Denver to Santiago takes 15h 20m
There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.
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  • How far is Denver Intl to Santiago Arturo Merino Benitez by plane?

    The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 12h 20m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Denver to Santiago?

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $551Free CancellationRating
7.4
9,050 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $562Free CancellationRating
7.5
1,886 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $575Free CancellationRating
7.6
1,567 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $629Free CancellationRating
7.2
11,039 reviews
Search American Airlines flights
DeltaPriceFrom $653Free CancellationRating
7.9
8,003 reviews
Search Delta flights
AeromexicoPriceFrom $823Free CancellationRating
7.4
1,658 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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