Which layover airport has the shortest connection time from Denver to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 2h 41m.

Which airport is the most popular layover for flights between Denver and Santiago?

Houston (IAH) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Denver to Santiago?

Flights via Miami (MIA) offer the lowest average round-trip price of $648.

What is the cheapest airline that flies from Denver Intl to Santiago Arturo Merino Benitez?

LATAM Airlines is the most popular carrier operating from Denver Intl to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

American Airlines, LATAM Airlines and Delta are the top three most popular airlines that fly to Santiago from Denver according to our data. American Airlines is the first choice among our users, with 27% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 5 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Denver to Santiago?

Flights connecting via Houston (IAH) have the shortest average one-way travel time: 13h 18m.

When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

As of August 2026, there are 5 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$311 Cheap Flights from Denver to Santiago in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:30 am - 5:35 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

19h 05m1 stop Los Angeles

8:13 am - 12:23 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

20h 10m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$679LATAM Airlines

Sun, Jan 17 - Fri, Jan 22

6:25 am - 5:35 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

19h 10m1 stop Los Angeles

9:50 pm - 12:07 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

18h 17m1 stop Atlanta Hartsfield-Jackson

$679LATAM Airlines

Sat, Nov 28 - Mon, Dec 7

9:49 pm - 3:43 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

25h 54m1 stop Panama City Tocumen Intl

12:20 pm - 5:10 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

32h 50m1 stop Panama City Tocumen Intl

$681Copa Airlines

Sun, Nov 29 - Thu, Dec 10

9:55 pm - 2:58 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

25h 03m1 stop Panama City Tocumen Intl

1:17 am - 5:14 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

19h 57m1 stop Panama City Tocumen Intl

$681Copa Airlines

Sun, Jan 31 - Sun, Feb 14

9:07 am - 7:45 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

18h 38m1 stop Dallas/Fort Worth

10:15 pm - 11:40 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

17h 25m1 stop Miami

$693American Airlines

Tue, Dec 8 - Mon, Dec 14

12:38 pm - 9:25 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

16h 47m1 stop Miami

11:45 pm - 2:18 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

18h 33m1 stop Dallas/Fort Worth

$693American Airlines

Tue, Dec 1 - Mon, Dec 14

6:00 am - 7:40 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

21h 40m1 stop Atlanta Hartsfield-Jackson

11:00 pm - 6:04 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

23h 04m1 stop Atlanta Hartsfield-Jackson

$693Delta

Fri, Jan 1 - Tue, Jan 19

12:00 pm - 7:40 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

15h 40m1 stop Atlanta Hartsfield-Jackson

8:13 am - 12:23 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

20h 10m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$693Delta

Tue, Jan 5 - Tue, Jan 19

3:40 pm - 8:50 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

13h 10m1 stop Houston George Bush Intcntl

10:45 pm - 12:45 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

18h 00m1 stop Houston George Bush Intcntl

$693United Airlines

Mon, Jan 25 - Sun, Feb 7

1:35 pm - 8:50 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

15h 15m1 stop Houston George Bush Intcntl

10:45 pm - 9:55 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

15h 10m1 stop Houston George Bush Intcntl

$693United Airlines

Sun, Jan 24 - Fri, Feb 5

Cheap last minute flights

Enter your travel dates to find the best prices.

9:39 am - 6:00 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

18h 21m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

11:55 pm - 8:15 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

23h 20m1 stop New York John F Kennedy Intl

$1,045Delta

Thu, Sep 3 - Sat, Sep 12

7:19 am - 6:00 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

20h 41m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

11:55 pm - 8:15 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

23h 20m1 stop New York John F Kennedy Intl

$1,045Delta

Thu, Sep 3 - Sat, Sep 12

7:19 am - 7:15 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

21h 56m1 stop Atlanta Hartsfield-Jackson

5:30 pm - 7:47 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

29h 17m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,045LATAM Airlines

Tue, Sep 1 - Wed, Sep 9

1:15 pm - 7:15 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

16h 00m1 stop Atlanta Hartsfield-Jackson

7:55 pm - 11:25 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

17h 30m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$1,045LATAM Airlines

Tue, Sep 1 - Thu, Sep 3

12:25 pm - 6:25 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

16h 00m1 stop Miami

8:50 pm - 8:53 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

26h 03m1 stop Miami

$1,061American Airlines

Tue, Sep 1 - Thu, Sep 3

10:43 pm - 5:10 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

28h 27m1 stop Panama City Tocumen Intl

5:14 am - 6:11 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

15h 57m1 stop Panama City Tocumen Intl

$1,129Copa Airlines

Thu, Sep 3 - Sat, Sep 12

3:35 pm - 11:22 pmDEN Denver Intl-SCL Santiago Arturo Merino Benitez

29h 47m2 stops Newark Panama City Tocumen Intl

5:14 am - 6:47 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

28h 33m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,208United Airlines

Thu, Sep 3 - Fri, Sep 11

12:40 pm - 7:32 pmDEN Denver Intl-SCL Santiago Arturo Merino Benitez

28h 52m2 stops Newark Panama City Tocumen Intl

5:14 am - 6:47 amSCL Santiago Arturo Merino Benitez-DEN Denver Intl

28h 33m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

$1,208United Airlines

Thu, Sep 3 - Fri, Sep 11

10:43 pm - 2:56 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

26h 13m1 stop Panama City Tocumen Intl

12:22 pm - 6:11 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

32h 49m1 stop Panama City Tocumen Intl

$1,274Copa Airlines

Thu, Sep 3 - Fri, Sep 11

1:20 pm - 7:05 amDEN Denver Intl-SCL Santiago Arturo Merino Benitez

15h 45m2 stops Charlotte Douglas Miami

9:30 pm - 11:03 pmSCL Santiago Arturo Merino Benitez-DEN Denver Intl

28h 33m1 stop Miami

$1,537American Airlines

Thu, Sep 3 - Sat, Sep 12

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

LATAM Airlines flights from Denver to Santiago

Our best LATAM Airlines deals on Denver to Santiago flight tickets

LATAM Airlines

Nov 28

DEN6:25 amDenver Intl

19h 10m

1 stop

SCL5:35 amSantiago Arturo Merino Benitez

Dec 7

SCL9:50 pmSantiago Arturo Merino Benitez

18h 17m

1 stop

DEN12:07 pmDenver Intl

$679

LATAM Airlines

Dec 7

DEN8:00 amDenver Intl

17h 35m

2 stops

SCL5:35 amSantiago Arturo Merino Benitez

Dec 11

SCL11:10 pmSantiago Arturo Merino Benitez

18h 06m

1 stop

DEN1:16 pmDenver Intl

$698

LATAM Airlines

Nov 28

DEN12:58 amDenver Intl

34h 02m

2 stops

SCL3:00 pmSantiago Arturo Merino Benitez

Dec 10

SCL11:10 pmSantiago Arturo Merino Benitez

16h 57m

1 stop

DEN12:07 pmDenver Intl

$707

Copa Airlines flights from Denver to Santiago

Our best Copa Airlines deals on Denver to Santiago flight tickets

Copa Airlines

Nov 29

DEN9:49 pmDenver Intl

25h 54m

1 stop

SCL3:43 amSantiago Arturo Merino Benitez

Dec 10

SCL12:20 pmSantiago Arturo Merino Benitez

32h 50m

1 stop

DEN5:10 pmDenver Intl

$681

Copa Airlines

Oct 19

DEN10:43 pmDenver Intl

25h 03m

1 stop

SCL2:46 amSantiago Arturo Merino Benitez

Oct 24

SCL5:22 amSantiago Arturo Merino Benitez

15h 49m

1 stop

DEN6:11 pmDenver Intl

$803

Copa Airlines

Sep 14

DEN10:43 pmDenver Intl

22h 39m

1 stop

SCL12:22 amSantiago Arturo Merino Benitez

Sep 21

SCL5:14 amSantiago Arturo Merino Benitez

15h 57m

1 stop

DEN6:11 pmDenver Intl

$993

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Sun 1/17

6:30 am-5:35 am

1 stop19h 05m

Santiago Arturo Merino Benitez

Fri 1/22

8:13 am-12:23 am

2 stops20h 10m

$679

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Sat 11/28

6:25 am-5:35 am

1 stop19h 10m

Santiago Arturo Merino Benitez

Mon 12/7

9:50 pm-12:07 pm

1 stop18h 17m

$679

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Sun 11/29

9:49 pm-3:43 am

1 stop25h 54m

Santiago Arturo Merino Benitez

Thu 12/10

12:20 pm-5:10 pm

1 stop32h 50m

$681

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Sun 1/31

9:55 pm-2:58 am

1 stop25h 03m

Santiago Arturo Merino Benitez

Sun 2/14

1:17 am-5:14 pm

1 stop19h 57m

$681

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Tue 12/8

9:07 am-7:45 am

1 stop18h 38m

Santiago Arturo Merino Benitez

Mon 12/14

10:15 pm-11:40 am

1 stop17h 25m

$693

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Tue 12/1

12:38 pm-9:25 am

1 stop16h 47m

Santiago Arturo Merino Benitez

Mon 12/14

11:45 pm-2:18 pm

1 stop18h 33m

$693

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Fri 1/1

6:00 am-7:40 am

1 stop21h 40m

Santiago Arturo Merino Benitez

Tue 1/19

11:00 pm-6:04 pm

1 stop23h 04m

$693

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Tue 1/5

12:00 pm-7:40 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Tue 1/19

8:13 am-12:23 am

2 stops20h 10m

$693

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Mon 1/25

3:40 pm-8:50 am

1 stop13h 10m

Santiago Arturo Merino Benitez

Sun 2/7

10:45 pm-12:45 pm

1 stop18h 00m

$693

Quickest round-trip

DenverSantiago

DEN Denver Intl - SCL Santiago Arturo Merino Benitez

DENSCL

Denver Intl

Sun 1/24

1:35 pm-8:50 am

1 stop15h 15m

Santiago Arturo Merino Benitez

Fri 2/5

10:45 pm-9:55 am

1 stop15h 10m

$693

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Denver and Santiago?

Prices are currently low for flights on this route.

Typical prices usually range from $715 to $1,059.
The lowest price recently found on this route was $679.

What is the cheapest month to fly to Santiago?

In general, November is the cheapest month to fly from Denver to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $735. If you don’t want to visit Santiago in November, then you should wait until June to fly from Denver, when ticket prices are also cheap, with an average price of $755.

How far in advance should I book a flight from Denver to Santiago?

You are more likely to see cheaper flights to Santiago from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $882 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Denver for as low as $586 on momondo.

Can stopping save me money on Denver to Santiago flights?

You could potentially save up to 20% on your flight if you consider stops on a Denver to Santiago flight.

How have Denver to Santiago flight prices changed over time?

As of August 2026, prices for Denver to Santiago flights are approximately 40% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Santiago (DEN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Santiago

Best Price Found	$311
Fastest flight time	13h 52m
Direct flights	None

The best one-way flight to Santiago from Denver in the past 72 hours is $311. The best round-trip flight deal from Denver to Santiago found on momondo in the last 72 hours is $679.

The fastest flight from Denver to Santiago takes 13h 52m

There are no direct flights from Denver to Santiago. There are no popular flight routes from Denver to Santiago.

Search flight deals

Frequently asked questions about flying from Denver to Santiago

How far is Denver Intl to Santiago Arturo Merino Benitez by plane?
The straight-line distance from Denver Intl to Santiago Arturo Merino Benitez is 5508.2 mi. 13h 52m is a normal flight duration for this route.
When did momondo last update prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
As of August 2026, there are 5 operators available to choose from for flights from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Denver Intl Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Denver to Santiago?
Based on momondo bookings for flights between Denver and Santiago, the leading airline is American Airlines, making up 25% of the total bookings. Other popular airlines include LATAM Airlines with 24%, Delta with 24%, and United Airlines with 20%.

Best airlines flying from Denver to Santiago

Compare and see reviews for airlines that fly from Denver to Santiago with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $544	Free Cancellation	Rating 7.4 1,987 reviews	Search LATAM Airlines flights
Delta	PriceFrom $544	Free Cancellation	Rating 7.8 8,535 reviews	Search Delta flights
Copa Airlines	PriceFrom $552	Free Cancellation	Rating 7.6 1,550 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $563	Free Cancellation	Rating 7.4 10,148 reviews	Search United Airlines flights
American Airlines	PriceFrom $593	Free Cancellation	Rating 7.1 12,021 reviews	Search American Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

San Fernando

Valle Nevado

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Denver to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Denver to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Denver which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Denver to Santiago?

momondo helps you find the best flight between Denver and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Denver to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Denver to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.