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Cheap flights from Denver to Panama City from $281

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:31 pm - 12:40 pmDEN  Denver Intl-PTY Panama City Tocumen Intl
12h 09m1 stop Miami
American Airlines Logo
3:13 pm - 11:59 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
9h 46m1 stop Miami
$627American Airlines
Mon, Mar 15 - Thu, Mar 18
American Airlines Logo
11:29 pm - 1:21 pmDEN  Denver Intl-PTY Panama City Tocumen Intl
11h 52m1 stop Miami
American Airlines Logo
2:39 pm - 11:59 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
11h 20m1 stop Miami
$627American Airlines
Mon, Feb 22 - Fri, Feb 26
American Airlines Logo
11:31 pm - 2:20 pmDEN  Denver Intl-PTY Panama City Tocumen Intl
13h 49m1 stop Miami
American Airlines Logo
3:13 pm - 11:59 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
9h 46m1 stop Miami
$627American Airlines
Tue, Mar 16 - Thu, Mar 18
Copa Airlines Logo
10:43 pm - 5:33 amDEN  Denver Intl-PTY Panama City Tocumen Intl
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:11 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
6h 15mnonstop
$629Copa Airlines
Sat, Oct 17 - Sat, Oct 24
Copa Airlines Logo
10:43 pm - 5:33 amDEN  Denver Intl-PTY Panama City Tocumen Intl
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:11 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
6h 15mnonstop
$629Copa Airlines
Sun, Oct 18 - Sat, Oct 24
Copa Airlines Logo
9:49 pm - 5:33 amDEN  Denver Intl-PTY Panama City Tocumen Intl
5h 44mnonstop
Copa Airlines Logo
12:56 pm - 5:02 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
6h 06mnonstop
$629Copa Airlines
Sun, Nov 8 - Fri, Nov 13
Multiple Airlines Logo
12:50 pm - 10:35 amDEN  Denver Intl-PTY Panama City Tocumen Intl
19h 45m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl
Multiple Airlines Logo
3:55 pm - 12:00 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
22h 05m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl
$640Multiple Airlines
Thu, Feb 4 - Sun, Feb 7
Delta Logo
12:59 am - 12:59 pmDEN  Denver Intl-PTY Panama City Tocumen Intl
11h 00m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:24 pm - 11:12 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
9h 48m1 stop Atlanta Hartsfield-Jackson
$644Delta
Sun, Oct 11 - Fri, Oct 16
United Airlines Logo
8:39 pm - 2:45 pmDEN  Denver Intl-PTY Panama City Tocumen Intl
16h 06m1 stop Houston George Bush Intcntl
United Airlines Logo
4:41 pm - 11:27 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
8h 46m1 stop Houston George Bush Intcntl
$732United Airlines
Fri, Feb 19 - Mon, Mar 1
United Airlines Logo
5:00 am - 5:12 pmDEN  Denver Intl-PTY Panama City Tocumen Intl
10h 12m1 stop Houston George Bush Intcntl
United Airlines Logo
8:55 am - 9:52 pmPTY  Panama City Tocumen Intl-DEN Denver Intl
14h 57m1 stop Houston George Bush Intcntl
$732United Airlines
Sun, Jan 10 - Tue, Jan 19

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Delta flights from Denver to Panama City

Our best Delta deals on Denver to Panama City flight tickets
Delta
Sep 25
DEN12:50 amDenver Intl
11h 08m
1 stop
PTY12:58 pmPanama City Tocumen Intl
Oct 2
PTY2:23 pmPanama City Tocumen Intl
29h 42m
1 stop
DEN7:05 pmDenver Intl
$632
Delta
Oct 18
DEN12:59 amDenver Intl
11h 00m
1 stop
PTY12:59 pmPanama City Tocumen Intl
Oct 24
PTY2:24 pmPanama City Tocumen Intl
9h 08m
1 stop
DEN10:32 pmDenver Intl
$644
Delta
Nov 8
DEN12:58 amDenver Intl
11h 04m
1 stop
PTY2:02 pmPanama City Tocumen Intl
Jan 23
PTY3:20 pmPanama City Tocumen Intl
9h 59m
1 stop
DEN11:19 pmDenver Intl
$693

GOL flights from Denver to Panama City

Our best GOL deals on Denver to Panama City flight tickets
GOL
Oct 15
DEN10:39 amDenver Intl
25h 23m
2 stops
PTY1:02 pmPanama City Tocumen Intl
Oct 22
PTY2:02 pmPanama City Tocumen Intl
9h 44m
1 stop
DEN10:46 pmDenver Intl
$700
GOL
Sep 30
DEN9:03 amDenver Intl
26h 13m
2 stops
PTY12:16 pmPanama City Tocumen Intl
Oct 6
PTY2:02 pmPanama City Tocumen Intl
19h 31m
2 stops
DEN8:33 amDenver Intl
$705
GOL
Sep 21
DEN9:03 amDenver Intl
26h 23m
2 stops
PTY12:26 pmPanama City Tocumen Intl
Oct 3
PTY1:16 pmPanama City Tocumen Intl
10h 47m
1 stop
DEN11:03 pmDenver Intl
$754

momondo Fare Finder

 
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Mon 3/15

11:31 pm-12:40 pm

1 stop12h 09m

Panama City Tocumen Intl

Thu 3/18

3:13 pm-11:59 pm

1 stop9h 46m

$627

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Mon 2/22

11:29 pm-1:21 pm

1 stop11h 52m

Panama City Tocumen Intl

Fri 2/26

2:39 pm-11:59 pm

1 stop11h 20m

$627

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Tue 3/16

11:31 pm-2:20 pm

1 stop13h 49m

Panama City Tocumen Intl

Thu 3/18

3:13 pm-11:59 pm

1 stop9h 46m

$627

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Sat 10/17

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Sat 10/24

12:56 pm-6:11 pm

Nonstop6h 15m

$629

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Sun 10/18

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Sat 10/24

12:56 pm-6:11 pm

Nonstop6h 15m

$629
Quickest round-trip

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Sun 11/8

9:49 pm-5:33 am

Nonstop5h 44m

Panama City Tocumen Intl

Fri 11/13

12:56 pm-5:02 pm

Nonstop6h 06m

$629

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Thu 2/4

12:50 pm-10:35 am

2 stops19h 45m

Panama City Tocumen Intl

Sun 2/7

3:55 pm-12:00 pm

2 stops22h 05m

$640

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Sun 10/11

12:59 am-12:59 pm

1 stop11h 00m

Panama City Tocumen Intl

Fri 10/16

2:24 pm-11:12 pm

1 stop9h 48m

$644

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Fri 2/19

8:39 pm-2:45 pm

1 stop16h 06m

Panama City Tocumen Intl

Mon 3/1

4:41 pm-11:27 pm

1 stop8h 46m

$732

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Sun 1/10

5:00 am-5:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Tue 1/19

8:55 am-9:52 pm

1 stop14h 57m

$732

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Denver to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Panama City?

Prices are currently typical for flights on this route.

Typical prices usually range from $543 to $886.
The lowest price recently found on this route was $629.

What is the cheapest month to fly to Panama City?

In general, April is the cheapest month to fly from Denver to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $589. If you’re not able to fly to Panama City in April, then May is your next best option. Flight prices from Denver to Panama City during May average around $602.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $540. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $634. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight from Denver to Panama City?

You are more likely to see cheaper flights to Panama City from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $675 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Denver for as low as $585 on momondo.

What cabin class options are available on Denver to Panama City flights?

There are 3 cabin classes available to choose from on Denver to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama City flights?

You could potentially save up to 86% on your flight if you consider stops on a Denver to Panama City flight.

How have Denver to Panama City flight prices changed over time?

As of September 2026, prices for Denver to Panama City flights are approximately 11% cheaper when compared to flights at the same time last year.

When to book flights from Denver to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama City

Best Price Found

$281

Fastest flight time

5h 35m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Denver in the past 72 hours is $281. The best round-trip flight deal from Denver to Panama City found on momondo in the last 72 hours is $627.
The fastest flight from Denver to Panama City takes 5h 35m
Direct flights go from Denver to Panama City every day.
There is 1 airport in Panama City. From Denver there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from Denver to Panama City

  • How far is Denver Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2639.1 mi away from Denver Intl. Flights usually cover this in 5h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Denver to Panama City?

  • What is the most popular airline from Denver to Panama City?

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $493Free CancellationRating
7.6
1,543 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $549Free CancellationRating
7.4
10,232 reviews
Search United Airlines flights
American AirlinesPriceFrom $554Free CancellationRating
7.0
12,087 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Denver to Panama City for you.

Can I find flights from Denver to Panama City with flexible booking policies on momondo?

All flight searches from Denver to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Denver to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Denver. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Denver to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Denver and alert you when they change.

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