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Cheap flights from Denver to Panama City from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama City departing on 6/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:40 pm - 1:55 am
DEN
-
PTY
25h 15m
3 stops
Multiple Airlines Logo
10:10 am - 8:37 am
PTY
-
DEN
23h 27m
2 stops
$532Multiple Airlines
Wed, Jul 1 - Tue, Jul 7
Multiple Airlines Logo
11:40 pm - 1:55 am
DEN
-
PTY
25h 15m
3 stops
Multiple Airlines Logo
5:30 am - 8:37 am
PTY
-
DEN
28h 07m
3 stops
$534Multiple Airlines
Wed, Jul 1 - Tue, Jul 7
Multiple Airlines Logo
11:59 pm - 10:30 am
DEN
-
PTY
33h 31m
2 stops
Multiple Airlines Logo
3:50 pm - 10:59 pm
PTY
-
DEN
32h 09m
2 stops
$602Multiple Airlines
Thu, Apr 30 - Thu, May 7
Multiple Airlines Logo
5:05 am - 7:20 pm
DEN
-
PTY
13h 15m
2 stops
Multiple Airlines Logo
6:34 pm - 9:08 pm
PTY
-
DEN
27h 34m
2 stops
$603Multiple Airlines
Thu, Jun 11 - Wed, Jun 17
Copa Airlines Logo
10:43 pm - 5:33 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:20 pm
PTY
-
DEN
6h 24mnonstop
$607Copa Airlines
Thu, Jun 25 - Wed, Jul 8
Multiple Airlines Logo
11:59 pm - 2:55 pm
DEN
-
PTY
37h 56m
3 stops
Multiple Airlines Logo
3:50 pm - 10:59 pm
PTY
-
DEN
32h 09m
2 stops
$609Multiple Airlines
Thu, Apr 30 - Thu, May 7
United Airlines Logo
9:10 pm - 4:12 pm
DEN
-
PTY
18h 02m
1 stop
United Airlines Logo
11:35 am - 8:39 am
PTY
-
DEN
23h 04m
3 stops
$612United Airlines
Sat, Jul 18 - Sat, Jan 16
Multiple Airlines Logo
11:59 pm - 10:30 am
DEN
-
PTY
33h 31m
2 stops
Multiple Airlines Logo
3:50 pm - 10:59 pm
PTY
-
DEN
32h 09m
2 stops
$621Multiple Airlines
Sat, May 2 - Thu, May 7
United Airlines Logo
9:10 pm - 2:14 pm
DEN
-
PTY
16h 04m
1 stop
United Airlines Logo
7:55 am - 4:44 pm
PTY
-
DEN
9h 49m
1 stop
$622United Airlines
Wed, Jul 8 - Mon, Jul 13
Copa Airlines Logo
10:43 pm - 5:33 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$628Copa Airlines
Sun, Jun 7 - Thu, Jun 11

Copa Airlines flights from Denver to Panama City

Our best Copa Airlines deals on Denver to Panama City flight tickets
Copa Airlines
Aug 3
DEN10:43 pmDenver Intl
5h 50m
PTY5:33 amPanama City Tocumen Intl
Aug 19
PTY12:56 pmPanama City Tocumen Intl
6h 24m
DEN6:20 pmDenver Intl
$597
Copa Airlines
Jun 25
DEN10:43 pmDenver Intl
5h 50m
PTY5:33 amPanama City Tocumen Intl
Jul 8
PTY12:56 pmPanama City Tocumen Intl
6h 24m
DEN6:20 pmDenver Intl
$607
Copa Airlines
Aug 15
DEN10:43 pmDenver Intl
5h 50m
PTY5:33 amPanama City Tocumen Intl
Aug 22
PTY12:56 pmPanama City Tocumen Intl
6h 24m
DEN6:20 pmDenver Intl
$627

United Airlines flights from Denver to Panama City

Our best United Airlines deals on Denver to Panama City flight tickets
United Airlines
Aug 15
DEN7:40 amDenver Intl
9h 57m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 5
PTY3:30 pmPanama City Tocumen Intl
18h 25m
1 stop
DEN8:55 amDenver Intl
$612
United Airlines
Jul 8
DEN9:10 pmDenver Intl
16h 04m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Jul 13
PTY7:55 amPanama City Tocumen Intl
9h 49m
1 stop
DEN4:44 pmDenver Intl
$622
United Airlines
Sep 12
DEN5:00 amDenver Intl
8h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Sep 20
PTY3:30 pmPanama City Tocumen Intl
20h 39m
1 stop
DEN11:09 amDenver Intl
$623

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 7/1

11:40 pm-1:55 am

3 stops25h 15m

Panama City Tocumen Intl

Tue 7/7

10:10 am-8:37 am

2 stops23h 27m

$532

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 7/1

11:40 pm-1:55 am

3 stops25h 15m

Panama City Tocumen Intl

Tue 7/7

5:30 am-8:37 am

3 stops28h 07m

$534

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 4/30

11:59 pm-10:30 am

2 stops33h 31m

Panama City Tocumen Intl

Thu 5/7

3:50 pm-10:59 pm

2 stops32h 09m

$602

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 6/11

5:05 am-7:20 pm

2 stops13h 15m

Panama City Tocumen Intl

Wed 6/17

6:34 pm-9:08 pm

2 stops27h 34m

$603
Quickest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 6/25

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Wed 7/8

12:56 pm-6:20 pm

Nonstop6h 24m

$607

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 4/30

11:59 pm-2:55 pm

3 stops37h 56m

Panama City Tocumen Intl

Thu 5/7

3:50 pm-10:59 pm

2 stops32h 09m

$609

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 7/18

9:10 pm-4:12 pm

1 stop18h 02m

Panama City Tocumen Intl

Sat 1/16

11:35 am-8:39 am

3 stops23h 04m

$612

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 5/2

11:59 pm-10:30 am

2 stops33h 31m

Panama City Tocumen Intl

Thu 5/7

3:50 pm-10:59 pm

2 stops32h 09m

$621

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 7/8

9:10 pm-2:14 pm

1 stop16h 04m

Panama City Tocumen Intl

Mon 7/13

7:55 am-4:44 pm

1 stop9h 49m

$622

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 6/7

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Thu 6/11

12:56 pm-6:25 pm

Nonstop6h 29m

$628

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Denver to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Panama City?

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Denver to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $540. If you’re not able to fly to Panama City in August, then January is your next best option. Flight prices from Denver to Panama City during January average around $589.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $528. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $612. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight from Denver to Panama City?

You are more likely to see cheaper flights to Panama City from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $631 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Denver for as low as $528 on momondo.

What cabin class options are available on Denver to Panama City flights?

There are 3 cabin classes available to choose from on Denver to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama City flights?

No. A direct flight is the cheapest option for a flight between Denver to Panama City.

How have Denver to Panama City flight prices changed over time?

As of April 2026, prices for Denver to Panama City flights are approximately 49% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama City

Best Price Found

$250

Fastest flight time

5h 42m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in Panama City

1 airport
The best one-way flight to Panama City from Denver in the past 72 hours is $250. The best round-trip flight deal from Denver to Panama City found on momondo in the last 72 hours is $544.
The fastest flight from Denver to Panama City takes 5h 42m
Direct flights go from Denver to Panama City on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Panama City. From Denver there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from Denver to Panama City

  • How far is Denver Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2639.1 mi away from Denver Intl. Flights usually cover this in 5h 42m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Denver to Panama City?

  • What is the most popular airline from Denver to Panama City?

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $475Free CancellationRating
7.5
1,577 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $527Free CancellationRating
7.4
9,643 reviews
Search United Airlines flights

  • Copa Airlines Flights From Denver to Panama City

    Copa Airlines is one of the most popular airlines flying from Denver to Panama City, operating 6 flights/week on average for this route. A good Copa Airlines flight deal for Denver to Panama City starts from $475 round-trip, up to an average price of $616. Our users have rated Copa Airlines at 7.5/10.

  • United Airlines Flights From Denver to Panama City

    Another popular option for Denver to Panama City flights is United Airlines (7.4/10, 9,643 ratings). United Airlines flies from Denver to Panama City around 6 times per week, with deals starting from $527 round-trip and rising to an average price of around $680.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Denver to Panama City for you.

Can I find flights from Denver to Panama City with flexible booking policies on momondo?

All flight searches from Denver to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Denver to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Denver. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Denver to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Denver and alert you when they change.

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