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Cheap flights from Denver to Panama City from $180

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama City departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Denver to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:34 am - 2:15 pm
DEN
-
PTY
25h 41m
2 stops
Multiple Airlines Logo
9:33 pm - 10:30 am
PTY
-
DEN
13h 57m
1 stop
$443Multiple Airlines
Wed, Apr 15 - Mon, Apr 20
Multiple Airlines Logo
11:25 pm - 4:06 pm
DEN
-
PTY
14h 41m
1 stop
Multiple Airlines Logo
6:16 pm - 8:26 am
PTY
-
DEN
15h 10m
1 stop
$473Multiple Airlines
Wed, Mar 4 - Tue, Mar 17
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
3:10 pm - 10:30 am
PTY
-
DEN
20h 20m
2 stops
$477Multiple Airlines
Mon, May 4 - Mon, May 11
Multiple Airlines Logo
11:05 pm - 7:20 pm
DEN
-
PTY
19h 15m
1 stop
Multiple Airlines Logo
9:33 pm - 10:30 am
PTY
-
DEN
13h 57m
1 stop
$479Multiple Airlines
Wed, Apr 15 - Mon, Apr 20
Multiple Airlines Logo
11:25 pm - 10:40 am
DEN
-
PTY
9h 15m
1 stop
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
11h 53m
1 stop
$483Multiple Airlines
Wed, Mar 4 - Mon, Mar 16
Multiple Airlines Logo
10:30 am - 8:06 am
DEN
-
PTY
20h 36m
2 stops
Multiple Airlines Logo
9:33 pm - 10:30 am
PTY
-
DEN
13h 57m
1 stop
$491Multiple Airlines
Tue, Apr 7 - Tue, Apr 14
Multiple Airlines Logo
10:30 am - 8:06 am
DEN
-
PTY
20h 36m
2 stops
Multiple Airlines Logo
9:33 pm - 10:30 am
PTY
-
DEN
13h 57m
1 stop
$492Multiple Airlines
Tue, Apr 7 - Tue, Apr 28
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$497Copa Airlines
Sat, May 2 - Sat, May 9
Multiple Airlines Logo
11:25 pm - 4:06 pm
DEN
-
PTY
14h 41m
1 stop
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
12h 53m
1 stop
$500Multiple Airlines
Mon, Mar 2 - Fri, Mar 6
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$502Copa Airlines
Sun, May 24 - Sun, May 31

United Airlines flights from Denver to Panama City

Our best United Airlines deals on Denver to Panama City flight tickets
United Airlines
Jul 16
DEN9:10 pmDenver Intl
16h 04m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Jul 26
PTY3:30 pmPanama City Tocumen Intl
9h 27m
1 stop
DEN11:57 pmDenver Intl
$512
United Airlines
Apr 9
DEN8:23 pmDenver Intl
16h 51m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Apr 19
PTY10:00 amPanama City Tocumen Intl
14h 57m
1 stop
DEN11:57 pmDenver Intl
$522
United Airlines
Mar 27
DEN6:17 amDenver Intl
11h 21m
1 stop
PTY6:38 pmPanama City Tocumen Intl
Apr 17
PTY7:55 amPanama City Tocumen Intl
11h 26m
1 stop
DEN6:21 pmDenver Intl
$533

American Airlines flights from Denver to Panama City

Our best American Airlines deals on Denver to Panama City flight tickets
American Airlines
Jul 28
DEN11:53 pmDenver Intl
11h 17m
1 stop
PTY12:10 pmPanama City Tocumen Intl
Aug 4
PTY1:10 pmPanama City Tocumen Intl
24h 47m
2 stops
DEN12:57 pmDenver Intl
$506
American Airlines
May 9
DEN11:30 pmDenver Intl
12h 16m
1 stop
PTY12:46 pmPanama City Tocumen Intl
May 22
PTY1:14 pmPanama City Tocumen Intl
25h 15m
2 stops
DEN1:29 pmDenver Intl
$511
American Airlines
May 2
DEN11:30 pmDenver Intl
12h 16m
1 stop
PTY12:46 pmPanama City Tocumen Intl
May 9
PTY1:49 pmPanama City Tocumen Intl
21h 50m
2 stops
DEN10:39 amDenver Intl
$516

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/15

11:34 am-2:15 pm

2 stops25h 41m

Panama City Tocumen Intl

Mon 4/20

9:33 pm-10:30 am

1 stop13h 57m

$443

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 3/4

11:25 pm-4:06 pm

1 stop14h 41m

Panama City Tocumen Intl

Tue 3/17

6:16 pm-8:26 am

1 stop15h 10m

$473

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 5/4

11:05 pm-7:20 pm

1 stop19h 15m

Panama City Tocumen Intl

Mon 5/11

3:10 pm-10:30 am

2 stops20h 20m

$477

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/15

11:05 pm-7:20 pm

1 stop19h 15m

Panama City Tocumen Intl

Mon 4/20

9:33 pm-10:30 am

1 stop13h 57m

$479

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 3/4

11:25 pm-10:40 am

1 stop9h 15m

Panama City Tocumen Intl

Mon 3/16

9:33 pm-8:26 am

1 stop11h 53m

$483

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 4/7

10:30 am-8:06 am

2 stops20h 36m

Panama City Tocumen Intl

Tue 4/14

9:33 pm-10:30 am

1 stop13h 57m

$491

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 4/7

10:30 am-8:06 am

2 stops20h 36m

Panama City Tocumen Intl

Tue 4/28

9:33 pm-10:30 am

1 stop13h 57m

$492

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 5/2

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Sat 5/9

12:56 pm-6:25 pm

Nonstop6h 29m

$497

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 3/2

11:25 pm-4:06 pm

1 stop14h 41m

Panama City Tocumen Intl

Fri 3/6

9:33 pm-8:26 am

1 stop12h 53m

$500

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 5/24

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Sun 5/31

12:56 pm-6:25 pm

Nonstop6h 29m

$502

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Denver to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Denver to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $537. If you’re not able to fly to Panama City in August, then April is your next best option. Flight prices from Denver to Panama City during April average around $551.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $526. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $607. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $625 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Denver for as low as $535 on momondo.

What cabin class options are available on Denver Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Denver Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama City flights?

You could potentially save up to 28% on your flight if you consider stops on a Denver to Panama City flight.

How have Denver to Panama City flight prices changed over time?

As of February 2026, prices for Denver to Panama City flights are approximately 62% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama City

Best Price Found

$213

Fastest flight time

5h 42m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Denver in the past 72 hours is $213. The best round-trip flight deal from Denver to Panama City found on momondo in the last 72 hours is $459.
The fastest flight from Denver to Panama City takes 5h 42m
Direct flights go from Denver to Panama City every day.
There is 1 airport in Panama City. From Denver there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • How far is Denver Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2639.1 mi away from Denver Intl. Flights usually cover this in 5h 42m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Denver to Panama City?

  • What is the most popular airline from Denver to Panama City?

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $470Free CancellationRating
7.5
1,559 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $473Free CancellationRating
7.2
11,288 reviews
Search American Airlines flights
United AirlinesPriceFrom $527Free CancellationRating
7.4
9,289 reviews
Search United Airlines flights

  • Copa Airlines Flights From Denver to Panama City

    Copa Airlines is one of the most popular airlines flying from Denver to Panama City, operating 9 flights/week on average for this route. A good Copa Airlines flight deal for Denver to Panama City starts from $470 round-trip, up to an average price of $613. Our users have rated Copa Airlines at 7.5/10.

  • United Airlines Flights From Denver to Panama City

    Another popular option for Denver to Panama City flights is United Airlines (7.4/10, 9,289 ratings). United Airlines flies from Denver to Panama City around 9 times per week, with deals starting from $527 round-trip and rising to an average price of around $683.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Denver to Panama City for you.

Can I find flights from Denver to Panama City with flexible booking policies on momondo?

All flight searches from Denver to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Denver to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Denver. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Denver to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Denver and alert you when they change.

An easier way to manage your Panama City trip

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