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Cheap flights from Denver to Panama City from $174

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama City departing on 1/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
7:30 am - 8:34 pmDEN-PTY
11h 04m1 stop
Multiple Airlines Logo
2:55 am - 9:04 pmPTY-DEN
20h 09m2 stops
$550Multiple Airlines
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Tue, Jan 27 - Fri, Jan 30
Multiple Airlines Logo
4:25 pm - 10:30 amDEN-PTY
16h 05m2 stops
Multiple Airlines Logo
1:45 pm - 2:05 pmPTY-DEN
26h 20m1 stop
$555Multiple Airlines
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Wed, Jan 7 - Fri, Jan 23
Multiple Airlines Logo
12:34 pm - 5:20 amDEN-PTY
14h 46m1 stop
Multiple Airlines Logo
7:50 pm - 9:04 pmPTY-DEN
27h 14m2 stops
$560Multiple Airlines
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Mon, Jan 12 - Mon, Jan 19
Multiple Airlines Logo
4:25 pm - 10:30 amDEN-PTY
16h 05m2 stops
Multiple Airlines Logo
1:45 pm - 10:05 amPTY-DEN
22h 20m1 stop
$561Multiple Airlines
Find Deal
Wed, Jan 7 - Wed, Jan 21
Multiple Airlines Logo
9:20 pm - 5:20 amDEN-PTY
30h 00m1 stop
Multiple Airlines Logo
1:45 pm - 10:05 amPTY-DEN
22h 20m1 stop
$562Multiple Airlines
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Tue, Jan 13 - Wed, Jan 21
United Airlines Logo
5:00 am - 2:45 pmDEN-PTY
7h 45m1 stop
United Airlines Logo
4:41 pm - 11:35 pmPTY-DEN
8h 54m1 stop
$563United Airlines
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Fri, Feb 20 - Sat, Feb 28
American Airlines Logo
11:26 pm - 1:50 pmDEN-PTY
12h 24m1 stop
American Airlines Logo
4:05 pm - 11:59 pmPTY-DEN
9h 54m1 stop
$564American Airlines
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Sat, Feb 14 - Sat, Feb 21
American Airlines Logo
11:26 pm - 1:50 pmDEN-PTY
12h 24m1 stop
American Airlines Logo
1:44 pm - 8:20 amPTY-DEN
19h 36m2 stops
$566American Airlines
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Sat, Feb 28 - Sun, Mar 8
Multiple Airlines Logo
6:00 am - 10:30 amDEN-PTY
26h 30m2 stops
Multiple Airlines Logo
1:45 pm - 10:00 amPTY-DEN
22h 15m1 stop
$567Multiple Airlines
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Sun, Jan 11 - Sun, Jan 18
American Airlines Logo
6:00 pm - 3:15 pmDEN-PTY
19h 15m2 stops
American Airlines Logo
2:50 pm - 8:27 amPTY-DEN
19h 37m2 stops
$568American Airlines
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Fri, Feb 13 - Sat, Feb 21

American Airlines flights from Denver to Panama City

Our best American Airlines deals on Denver to Panama City flight tickets
American Airlines
Mar 22
DEN5:58 pmDenver Intl
19h 24m
2 stops
PTY2:22 pmPanama City Tocumen Intl
Mar 31
PTY3:13 pmPanama City Tocumen Intl
9h 46m
1 stop
DEN11:59 pmDenver Intl
$554
Find similar
American Airlines
Apr 16
DEN1:00 amDenver Intl
10h 15m
1 stop
PTY12:15 pmPanama City Tocumen Intl
Apr 26
PTY1:55 pmPanama City Tocumen Intl
19h 20m
2 stops
DEN8:15 amDenver Intl
$559
Find similar
American Airlines
Feb 14
DEN11:26 pmDenver Intl
12h 24m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Feb 21
PTY4:05 pmPanama City Tocumen Intl
9h 54m
1 stop
DEN11:59 pmDenver Intl
$564
Find similar

United Airlines flights from Denver to Panama City

Our best United Airlines deals on Denver to Panama City flight tickets
United Airlines
Jan 7
DEN5:01 amDenver Intl
12h 37m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 22
PTY4:41 pmPanama City Tocumen Intl
9h 00m
1 stop
DEN11:41 pmDenver Intl
$576
Find similar
United Airlines
Mar 14
DEN5:00 amDenver Intl
12h 38m
1 stop
PTY6:38 pmPanama City Tocumen Intl
Mar 21
PTY3:41 pmPanama City Tocumen Intl
15h 59m
1 stop
DEN6:40 amDenver Intl
$627
Find similar
United Airlines
Dec 9
DEN7:25 pmDenver Intl
21h 24m
1 stop
PTY6:49 pmPanama City Tocumen Intl
Jan 15
PTY4:41 pmPanama City Tocumen Intl
9h 00m
1 stop
DEN11:41 pmDenver Intl
$719
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momondo Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/27

7:30 am-8:34 pm

1 stop11h 04m

Panama City Tocumen Intl

Fri 1/30

2:55 am-9:04 pm

2 stops20h 09m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 1/7

4:25 pm-10:30 am

2 stops16h 05m

Panama City Tocumen Intl

Fri 1/23

1:45 pm-2:05 pm

1 stop26h 20m

$555

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 1/12

12:34 pm-5:20 am

1 stop14h 46m

Panama City Tocumen Intl

Mon 1/19

7:50 pm-9:04 pm

2 stops27h 14m

$560

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 1/7

4:25 pm-10:30 am

2 stops16h 05m

Panama City Tocumen Intl

Wed 1/21

1:45 pm-10:05 am

1 stop22h 20m

$561

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/13

9:20 pm-5:20 am

1 stop30h 00m

Panama City Tocumen Intl

Wed 1/21

1:45 pm-10:05 am

1 stop22h 20m

$562

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

5:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Sat 2/28

4:41 pm-11:35 pm

1 stop8h 54m

$563

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/14

11:26 pm-1:50 pm

1 stop12h 24m

Panama City Tocumen Intl

Sat 2/21

4:05 pm-11:59 pm

1 stop9h 54m

$564

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

11:26 pm-1:50 pm

1 stop12h 24m

Panama City Tocumen Intl

Sun 3/8

1:44 pm-8:20 am

2 stops19h 36m

$566

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 1/11

6:00 am-10:30 am

2 stops26h 30m

Panama City Tocumen Intl

Sun 1/18

1:45 pm-10:00 am

1 stop22h 15m

$567

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/13

6:00 pm-3:15 pm

2 stops19h 15m

Panama City Tocumen Intl

Sat 2/21

2:50 pm-8:27 am

2 stops19h 37m

$568

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Denver to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Panama City?

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Denver to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $542. If you’re not able to fly to Panama City in August, then May is your next best option. Flight prices from Denver to Panama City during May average around $592.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $476. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $639. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Denver to Panama City during this time can be as low as $596. Try not to purchase tickets in the afternoon because they tend to be around $733. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $651 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Denver for as low as $564 on momondo.

What cabin class options are available on Denver Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Denver Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama City flights?

No. A direct flight is the cheapest option for a flight between Denver to Panama City.

How have Denver to Panama City flight prices changed over time?

As of December 2025, prices for Denver to Panama City flights are approximately 54% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama City

Best Price Found

$199

Fastest flight time

5h 42m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Denver in the past 72 hours is $199. The best round-trip flight deal from Denver to Panama City found on momondo in the last 72 hours is $453.
The fastest flight from Denver to Panama City takes 5h 42m
Direct flights go from Denver to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is Denver Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2639.1 mi away from Denver Intl. Flights usually cover this in 5h 55m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Denver to Panama City?

  • What is the most popular airline from Denver to Panama City?

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $492Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
DeltaPriceFrom $527Free CancellationRating
7.9
8,010 reviews
Search Delta flights
American AirlinesPriceFrom $527Free CancellationRating
7.2
11,046 reviews
Search American Airlines flights
United AirlinesPriceFrom $527Free CancellationRating
7.4
9,065 reviews
Search United Airlines flights

  • Copa Airlines Flights From Denver to Panama City

    Copa Airlines is one of the most popular airlines flying from Denver to Panama City, operating 7 flights/week on average for this route. A good Copa Airlines flight deal for Denver to Panama City starts from $492 round-trip, up to an average price of $647. Our users have rated Copa Airlines at 7.6/10.

  • United Airlines Flights From Denver to Panama City

    Another popular option for Denver to Panama City flights is United Airlines (7.4/10, 9,065 ratings). United Airlines flies from Denver to Panama City around 7 times per week, with deals starting from $527 round-trip and rising to an average price of around $688.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Denver to Panama City for you.

Can I find flights from Denver to Panama City with flexible booking policies on momondo?

All flight searches from Denver to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Denver to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Denver. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Denver to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Denver and alert you when they change.

An easier way to manage your Panama City trip

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