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Cheap flights from Denver to Panama City from $313

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama City departing on 6/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
10:43 pm - 5:33 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:11 pm
PTY
-
DEN
6h 15mnonstop
$510Copa Airlines
Mon, Sep 28 - Mon, Oct 5
Copa Airlines Logo
10:43 pm - 5:33 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:20 pm
PTY
-
DEN
6h 24mnonstop
$520Copa Airlines
Sun, Aug 16 - Mon, Aug 31
United Airlines Logo
5:00 am - 7:38 pm
DEN
-
PTY
12h 38m
1 stop
United Airlines Logo
8:55 am - 11:27 pm
PTY
-
DEN
16h 32m
1 stop
$525United Airlines
Sun, Nov 1 - Sat, Nov 14
Copa Airlines Logo
9:49 pm - 5:33 am
DEN
-
PTY
5h 44mnonstop
Copa Airlines Logo
12:56 pm - 5:02 pm
PTY
-
DEN
6h 06mnonstop
$528Copa Airlines
Wed, Nov 11 - Sun, Nov 22
American Airlines Logo
3:12 pm - 2:00 pm
DEN
-
PTY
21h 48m
2 stops
American Airlines Logo
2:43 pm - 11:01 pm
PTY
-
DEN
10h 18m
1 stop
$529American Airlines
Sat, Oct 17 - Sat, Nov 7
American Airlines Logo
11:55 pm - 12:39 pm
DEN
-
PTY
11h 44m
1 stop
American Airlines Logo
1:39 pm - 11:04 pm
PTY
-
DEN
10h 25m
1 stop
$530American Airlines
Sat, Aug 15 - Sat, Sep 5
American Airlines Logo
2:21 pm - 12:39 pm
DEN
-
PTY
21h 18m
2 stops
American Airlines Logo
1:16 pm - 11:33 am
PTY
-
DEN
23h 17m
2 stops
$534American Airlines
Thu, Sep 3 - Sat, Sep 12
United Airlines Logo
7:30 pm - 2:14 pm
DEN
-
PTY
17h 44m
1 stop
United Airlines Logo
10:00 am - 8:09 pm
PTY
-
DEN
11h 09m
1 stop
$535United Airlines
Sat, Aug 15 - Sat, Sep 5
Copa Airlines Logo
10:43 pm - 5:33 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:11 pm
PTY
-
DEN
6h 15mnonstop
$538Copa Airlines
Thu, Sep 3 - Sat, Sep 12
American Airlines Logo
4:21 pm - 12:39 pm
DEN
-
PTY
19h 18m
2 stops
American Airlines Logo
1:39 pm - 9:46 am
PTY
-
DEN
21h 07m
2 stops
$539American Airlines
Sat, Aug 15 - Sat, Sep 5

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American Airlines flights from Denver to Panama City

Our best American Airlines deals on Denver to Panama City flight tickets
American Airlines
Oct 17
DEN3:12 pmDenver Intl
21h 48m
2 stops
PTY2:00 pmPanama City Tocumen Intl
Nov 7
PTY2:43 pmPanama City Tocumen Intl
10h 18m
1 stop
DEN11:01 pmDenver Intl
$529
American Airlines
Aug 15
DEN11:55 pmDenver Intl
11h 44m
1 stop
PTY12:39 pmPanama City Tocumen Intl
Sep 5
PTY1:39 pmPanama City Tocumen Intl
10h 25m
1 stop
DEN11:04 pmDenver Intl
$530
American Airlines
Sep 3
DEN11:55 pmDenver Intl
11h 44m
1 stop
PTY12:39 pmPanama City Tocumen Intl
Sep 12
PTY1:16 pmPanama City Tocumen Intl
21h 39m
2 stops
DEN9:55 amDenver Intl
$534

United Airlines flights from Denver to Panama City

Our best United Airlines deals on Denver to Panama City flight tickets
United Airlines
Nov 1
DEN5:00 amDenver Intl
7h 45m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Nov 15
PTY4:41 pmPanama City Tocumen Intl
8h 46m
1 stop
DEN11:27 pmDenver Intl
$525
United Airlines
Aug 15
DEN7:30 pmDenver Intl
17h 44m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Sep 5
PTY10:00 amPanama City Tocumen Intl
11h 09m
1 stop
DEN8:09 pmDenver Intl
$535
United Airlines
Sep 28
DEN5:00 amDenver Intl
12h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Oct 5
PTY10:00 amPanama City Tocumen Intl
9h 21m
1 stop
DEN6:21 pmDenver Intl
$640

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 9/28

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Mon 10/5

12:56 pm-6:11 pm

Nonstop6h 15m

$510

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 8/16

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Mon 8/31

12:56 pm-6:20 pm

Nonstop6h 24m

$520

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 11/1

5:00 am-7:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Sat 11/14

8:55 am-11:27 pm

1 stop16h 32m

$525
Quickest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 11/11

9:49 pm-5:33 am

Nonstop5h 44m

Panama City Tocumen Intl

Sun 11/22

12:56 pm-5:02 pm

Nonstop6h 06m

$528

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 10/17

3:12 pm-2:00 pm

2 stops21h 48m

Panama City Tocumen Intl

Sat 11/7

2:43 pm-11:01 pm

1 stop10h 18m

$529

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 8/15

11:55 pm-12:39 pm

1 stop11h 44m

Panama City Tocumen Intl

Sat 9/5

1:39 pm-11:04 pm

1 stop10h 25m

$530

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 9/3

2:21 pm-12:39 pm

2 stops21h 18m

Panama City Tocumen Intl

Sat 9/12

1:16 pm-11:33 am

2 stops23h 17m

$534

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 8/15

7:30 pm-2:14 pm

1 stop17h 44m

Panama City Tocumen Intl

Sat 9/5

10:00 am-8:09 pm

1 stop11h 09m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 9/3

10:43 pm-5:33 am

Nonstop5h 50m

Panama City Tocumen Intl

Sat 9/12

12:56 pm-6:11 pm

Nonstop6h 15m

$538

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 8/15

4:21 pm-12:39 pm

2 stops19h 18m

Panama City Tocumen Intl

Sat 9/5

1:39 pm-9:46 am

2 stops21h 07m

$539

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Denver to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Panama City?

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Denver to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $573. If you’re not able to fly to Panama City in August, then April is your next best option. Flight prices from Denver to Panama City during April average around $593.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $533. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $620. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight from Denver to Panama City?

You are more likely to see cheaper flights to Panama City from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $646 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Denver for as low as $535 on momondo.

What cabin class options are available on Denver to Panama City flights?

There are 3 cabin classes available to choose from on Denver to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama City flights?

No. A direct flight is the cheapest option for a flight between Denver to Panama City.

How have Denver to Panama City flight prices changed over time?

As of June 2026, prices for Denver to Panama City flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama City

Best Price Found

$260

Fastest flight time

5h 43m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Denver in the past 72 hours is $260. The best round-trip flight deal from Denver to Panama City found on momondo in the last 72 hours is $534.
The fastest flight from Denver to Panama City takes 5h 43m
Direct flights go from Denver to Panama City every day.
There is 1 airport in Panama City. From Denver there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from Denver to Panama City

  • How far is Denver Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2639.1 mi away from Denver Intl. Flights usually cover this in 5h 43m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Denver to Panama City?

  • What is the most popular airline from Denver to Panama City?

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $464Free CancellationRating
7.5
1,569 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $527Free CancellationRating
7.4
9,804 reviews
Search United Airlines flights
American AirlinesPriceFrom $634Free CancellationRating
7.1
11,635 reviews
Search American Airlines flights

  • Copa Airlines Flights From Denver to Panama City

    Copa Airlines is one of the most popular airlines flying from Denver to Panama City, operating 3 flights/week on average for this route. A good Copa Airlines flight deal for Denver to Panama City starts from $464 round-trip, up to an average price of $624. Our users have rated Copa Airlines at 7.5/10.

  • United Airlines Flights From Denver to Panama City

    Another popular option for Denver to Panama City flights is United Airlines (7.4/10, 9,804 ratings). United Airlines flies from Denver to Panama City around 3 times per week, with deals starting from $527 round-trip and rising to an average price of around $681.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Denver to Panama City for you.

Can I find flights from Denver to Panama City with flexible booking policies on momondo?

All flight searches from Denver to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Denver to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Denver. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Denver to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Denver and alert you when they change.

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