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Cheap flights from Denver to Panama City from $210

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama City departing on 7/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Denver to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:59 am - 12:56 pm
DEN
-
PTY
10h 57m
1 stop
Delta Logo
2:21 pm - 11:49 pm
PTY
-
DEN
10h 28m
1 stop
$485Delta
Sun, Oct 4 - Wed, Oct 14
Delta Logo
12:00 pm - 1:13 pm
DEN
-
PTY
24h 13m
1 stop
Delta Logo
2:21 pm - 11:45 pm
PTY
-
DEN
10h 24m
1 stop
$495Delta
Fri, Sep 4 - Fri, Sep 18
Copa Airlines Logo
10:42 pm - 5:32 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$500Copa Airlines
Thu, Jun 25 - Mon, Jun 29
Copa Airlines Logo
10:42 pm - 5:32 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$518Copa Airlines
Fri, Jun 12 - Fri, Jun 19
Delta Logo
12:40 am - 1:09 pm
DEN
-
PTY
11h 29m
1 stop
Delta Logo
2:24 pm - 12:22 am
PTY
-
DEN
10h 58m
1 stop
$525Delta
Mon, Jun 15 - Wed, Jun 24
Copa Airlines Logo
10:42 pm - 5:32 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$536Copa Airlines
Sat, Jun 13 - Sat, Jun 20
Copa Airlines Logo
10:42 pm - 5:32 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$540Copa Airlines
Sun, Jun 7 - Wed, Jun 10
Copa Airlines Logo
10:42 pm - 5:32 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$558Copa Airlines
Fri, Jun 5 - Mon, Jun 22
Copa Airlines Logo
10:42 pm - 5:32 am
DEN
-
PTY
5h 50mnonstop
Copa Airlines Logo
12:56 pm - 6:20 pm
PTY
-
DEN
6h 24mnonstop
$569Copa Airlines
Thu, Jun 25 - Wed, Jul 8
Multiple Airlines Logo
11:40 pm - 8:06 am
DEN
-
PTY
31h 26m
1 stop
Multiple Airlines Logo
3:10 pm - 8:37 am
PTY
-
DEN
18h 27m
2 stops
$582Multiple Airlines
Tue, Aug 11 - Fri, Aug 28

American Airlines flights from Denver to Panama City

Our best American Airlines deals on Denver to Panama City flight tickets
American Airlines
May 29
DEN3:11 pmDenver Intl
20h 03m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Jun 1
PTY1:14 pmPanama City Tocumen Intl
23h 26m
2 stops
DEN11:40 amDenver Intl
$589
American Airlines
May 24
DEN2:21 pmDenver Intl
20h 53m
2 stops
PTY12:14 pmPanama City Tocumen Intl
May 31
PTY1:14 pmPanama City Tocumen Intl
23h 22m
2 stops
DEN11:36 amDenver Intl
$609
American Airlines
Jun 9
DEN3:57 pmDenver Intl
19h 16m
2 stops
PTY12:13 pmPanama City Tocumen Intl
Jun 16
PTY1:15 pmPanama City Tocumen Intl
10h 37m
1 stop
DEN10:52 pmDenver Intl
$619

Delta flights from Denver to Panama City

Our best Delta deals on Denver to Panama City flight tickets
Delta
Oct 4
DEN12:59 amDenver Intl
10h 57m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 13
PTY2:21 pmPanama City Tocumen Intl
10h 28m
1 stop
DEN11:49 pmDenver Intl
$485
Delta
Sep 4
DEN12:00 pmDenver Intl
24h 13m
1 stop
PTY1:13 pmPanama City Tocumen Intl
Sep 18
PTY2:21 pmPanama City Tocumen Intl
10h 24m
1 stop
DEN11:45 pmDenver Intl
$495
Delta
Jun 15
DEN12:40 amDenver Intl
11h 29m
1 stop
PTY1:09 pmPanama City Tocumen Intl
Jun 23
PTY2:24 pmPanama City Tocumen Intl
10h 58m
1 stop
DEN12:22 amDenver Intl
$525

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 10/4

12:59 am-12:56 pm

1 stop10h 57m

Panama City Tocumen Intl

Wed 10/14

2:21 pm-11:49 pm

1 stop10h 28m

$485

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 9/4

12:00 pm-1:13 pm

1 stop24h 13m

Panama City Tocumen Intl

Fri 9/18

2:21 pm-11:45 pm

1 stop10h 24m

$495

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 6/25

10:42 pm-5:32 am

Nonstop5h 50m

Panama City Tocumen Intl

Mon 6/29

12:56 pm-6:25 pm

Nonstop6h 29m

$500

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 6/12

10:42 pm-5:32 am

Nonstop5h 50m

Panama City Tocumen Intl

Fri 6/19

12:56 pm-6:25 pm

Nonstop6h 29m

$518

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 6/15

12:40 am-1:09 pm

1 stop11h 29m

Panama City Tocumen Intl

Wed 6/24

2:24 pm-12:22 am

1 stop10h 58m

$525

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 6/13

10:42 pm-5:32 am

Nonstop5h 50m

Panama City Tocumen Intl

Sat 6/20

12:56 pm-6:25 pm

Nonstop6h 29m

$536

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 6/7

10:42 pm-5:32 am

Nonstop5h 50m

Panama City Tocumen Intl

Wed 6/10

12:56 pm-6:25 pm

Nonstop6h 29m

$540

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 6/5

10:42 pm-5:32 am

Nonstop5h 50m

Panama City Tocumen Intl

Mon 6/22

12:56 pm-6:25 pm

Nonstop6h 29m

$558
Quickest round-trip

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 6/25

10:42 pm-5:32 am

Nonstop5h 50m

Panama City Tocumen Intl

Wed 7/8

12:56 pm-6:20 pm

Nonstop6h 24m

$569

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 8/11

11:40 pm-8:06 am

1 stop31h 26m

Panama City Tocumen Intl

Fri 8/28

3:10 pm-8:37 am

2 stops18h 27m

$582

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Denver to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Panama City?

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Denver to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $546. If you’re not able to fly to Panama City in August, then January is your next best option. Flight prices from Denver to Panama City during January average around $591.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $535. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $620. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight from Denver to Panama City?

You are more likely to see cheaper flights to Panama City from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $637 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Denver for as low as $528 on momondo.

Can stopping save me money on Denver to Panama City flights?

No. A direct flight is the cheapest option for a flight between Denver to Panama City.

How have Denver to Panama City flight prices changed over time?

As of May 2026, prices for Denver to Panama City flights are approximately 9% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama City

Best Price Found

$255

Fastest flight time

5h 42m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Denver in the past 72 hours is $255. The best round-trip flight deal from Denver to Panama City found on momondo in the last 72 hours is $550.
The fastest flight from Denver to Panama City takes 5h 42m
Direct flights go from Denver to Panama City every day.
There is 1 airport in Panama City. From Denver there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from Denver to Panama City

  • How far is Denver Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2639.1 mi away from Denver Intl. Flights usually cover this in 5h 42m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Denver to Panama City?

  • What is the most popular airline from Denver to Panama City?

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $473Free CancellationRating
7.5
1,584 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $527Free CancellationRating
7.4
9,715 reviews
Search United Airlines flights

  • Copa Airlines Flights From Denver to Panama City

    Copa Airlines is one of the most popular airlines flying from Denver to Panama City, operating 8 flights/week on average for this route. A good Copa Airlines flight deal for Denver to Panama City starts from $473 round-trip, up to an average price of $621. Our users have rated Copa Airlines at 7.5/10.

  • United Airlines Flights From Denver to Panama City

    Another popular option for Denver to Panama City flights is United Airlines (7.4/10, 9,715 ratings). United Airlines flies from Denver to Panama City around 8 times per week, with deals starting from $527 round-trip and rising to an average price of around $679.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Denver to Panama City for you.

Can I find flights from Denver to Panama City with flexible booking policies on momondo?

All flight searches from Denver to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Denver to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Denver. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Denver to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Denver and alert you when they change.

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