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Cheap flights from Denver to Panama City from $186

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama City departing on 2/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Denver to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
5:59 pm - 2:55 pm
DEN
-
PTY
18h 56m
3 stops
Avianca Logo
7:50 pm - 6:24 pm
PTY
-
DEN
24h 34m
2 stops
$512Avianca
Tue, Jan 27 - Fri, Jan 30
Avianca Logo
5:59 pm - 10:30 am
DEN
-
PTY
14h 31m
2 stops
Avianca Logo
7:50 pm - 6:24 pm
PTY
-
DEN
24h 34m
2 stops
$530Avianca
Tue, Jan 27 - Fri, Jan 30
Multiple Airlines Logo
11:59 pm - 2:55 pm
DEN
-
PTY
36h 56m
3 stops
Multiple Airlines Logo
3:50 pm - 1:44 pm
PTY
-
DEN
22h 54m
2 stops
$532Multiple Airlines
Tue, Mar 3 - Thu, Mar 12
Multiple Airlines Logo
11:35 am - 6:55 pm
DEN
-
PTY
29h 20m
3 stops
Multiple Airlines Logo
7:50 pm - 10:42 am
PTY
-
DEN
40h 52m
3 stops
$533Multiple Airlines
Tue, Jan 27 - Fri, Jan 30
Copa Airlines Logo
10:51 pm - 5:33 am
DEN
-
PTY
5h 42mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$536Copa Airlines
Wed, Apr 15 - Wed, Apr 29
Avianca Logo
5:59 pm - 2:55 pm
DEN
-
PTY
18h 56m
3 stops
Avianca Logo
7:50 pm - 6:14 pm
PTY
-
DEN
24h 24m
2 stops
$537Avianca
Tue, Feb 10 - Mon, Feb 23
Multiple Airlines Logo
11:20 am - 2:00 pm
DEN
-
PTY
24h 40m
2 stops
Multiple Airlines Logo
10:26 am - 10:10 pm
PTY
-
DEN
13h 44m
1 stop
$544Multiple Airlines
Sat, Feb 7 - Sun, Feb 15
Multiple Airlines Logo
11:25 pm - 4:06 pm
DEN
-
PTY
14h 41m
1 stop
Multiple Airlines Logo
9:33 pm - 8:26 am
PTY
-
DEN
11h 53m
1 stop
$545Multiple Airlines
Tue, Mar 3 - Sun, Mar 15
Multiple Airlines Logo
11:25 pm - 8:37 pm
DEN
-
PTY
19h 12m
1 stop
Multiple Airlines Logo
5:50 pm - 8:26 am
PTY
-
DEN
15h 36m
2 stops
$547Multiple Airlines
Tue, Mar 3 - Sun, Mar 15
Copa Airlines Logo
10:48 pm - 5:33 am
DEN
-
PTY
5h 45mnonstop
Copa Airlines Logo
12:56 pm - 6:25 pm
PTY
-
DEN
6h 29mnonstop
$549Copa Airlines
Sat, Mar 28 - Fri, Apr 3

American Airlines flights from Denver to Panama City

Our best American Airlines deals on Denver to Panama City flight tickets
American Airlines
Apr 16
DEN3:59 pmDenver Intl
19h 37m
2 stops
PTY12:36 pmPanama City Tocumen Intl
Apr 26
PTY1:49 pmPanama City Tocumen Intl
21h 07m
2 stops
DEN9:56 amDenver Intl
$560
American Airlines
Apr 8
DEN3:59 pmDenver Intl
19h 37m
2 stops
PTY12:36 pmPanama City Tocumen Intl
Apr 19
PTY1:49 pmPanama City Tocumen Intl
21h 07m
2 stops
DEN9:56 amDenver Intl
$567
American Airlines
Apr 17
DEN3:59 pmDenver Intl
19h 37m
2 stops
PTY12:36 pmPanama City Tocumen Intl
Apr 26
PTY1:49 pmPanama City Tocumen Intl
21h 07m
2 stops
DEN9:56 amDenver Intl
$580

Copa Airlines flights from Denver to Panama City

Our best Copa Airlines deals on Denver to Panama City flight tickets
Copa Airlines
Apr 15
DEN10:51 pmDenver Intl
5h 42m
PTY5:33 amPanama City Tocumen Intl
Apr 29
PTY12:56 pmPanama City Tocumen Intl
6h 29m
DEN6:25 pmDenver Intl
$536
Copa Airlines
Mar 28
DEN10:48 pmDenver Intl
5h 45m
PTY5:33 amPanama City Tocumen Intl
Apr 3
PTY12:56 pmPanama City Tocumen Intl
6h 29m
DEN6:25 pmDenver Intl
$549
Copa Airlines
May 12
DEN5:00 amDenver Intl
10h 12m
1 stop
PTY4:12 pmPanama City Tocumen Intl
May 26
PTY10:00 amPanama City Tocumen Intl
12h 23m
1 stop
DEN9:23 pmDenver Intl
$550

momondo Fare Finder

 
Customize your flight search to find flights from Denver to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from Denver to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/27

5:59 pm-2:55 pm

3 stops18h 56m

Panama City Tocumen Intl

Fri 1/30

7:50 pm-6:24 pm

2 stops24h 34m

$512

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/27

5:59 pm-10:30 am

2 stops14h 31m

Panama City Tocumen Intl

Fri 1/30

7:50 pm-6:24 pm

2 stops24h 34m

$530

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 3/3

11:59 pm-2:55 pm

3 stops36h 56m

Panama City Tocumen Intl

Thu 3/12

3:50 pm-1:44 pm

2 stops22h 54m

$532

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/27

11:35 am-6:55 pm

3 stops29h 20m

Panama City Tocumen Intl

Fri 1/30

7:50 pm-10:42 am

3 stops40h 52m

$533

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/15

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Wed 4/29

12:56 pm-6:25 pm

Nonstop6h 29m

$536

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 2/10

5:59 pm-2:55 pm

3 stops18h 56m

Panama City Tocumen Intl

Mon 2/23

7:50 pm-6:14 pm

2 stops24h 24m

$537

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/7

11:20 am-2:00 pm

2 stops24h 40m

Panama City Tocumen Intl

Sun 2/15

10:26 am-10:10 pm

1 stop13h 44m

$544

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 3/3

11:25 pm-4:06 pm

1 stop14h 41m

Panama City Tocumen Intl

Sun 3/15

9:33 pm-8:26 am

1 stop11h 53m

$545

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 3/3

11:25 pm-8:37 pm

1 stop19h 12m

Panama City Tocumen Intl

Sun 3/15

5:50 pm-8:26 am

2 stops15h 36m

$547

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 3/28

10:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Fri 4/3

12:56 pm-6:25 pm

Nonstop6h 29m

$549

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Denver to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Denver and Panama City?

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Denver to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $550. If you’re not able to fly to Panama City in August, then May is your next best option. Flight prices from Denver to Panama City during May average around $560.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $524. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $626. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $641 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Denver for as low as $558 on momondo.

What cabin class options are available on Denver Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Denver Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama City flights?

You could potentially save up to 39% on your flight if you consider stops on a Denver to Panama City flight.

How have Denver to Panama City flight prices changed over time?

As of January 2026, prices for Denver to Panama City flights are approximately 17% more expensive when compared to flights at the same time last year.

When to book flights from Denver to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama City

Best Price Found

$284

Fastest flight time

5h 42m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Denver in the past 72 hours is $284. The best round-trip flight deal from Denver to Panama City found on momondo in the last 72 hours is $451.
The fastest flight from Denver to Panama City takes 5h 42m
Direct flights go from Denver to Panama City every day.
There is 1 airport in Panama City. From Denver there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • How far is Denver Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2639.1 mi away from Denver Intl. Flights usually cover this in 5h 42m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Denver to Panama City?

  • What is the most popular airline from Denver to Panama City?

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $464Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
DeltaPriceFrom $527Free CancellationRating
7.9
8,040 reviews
Search Delta flights
American AirlinesPriceFrom $527Free CancellationRating
7.2
11,119 reviews
Search American Airlines flights
United AirlinesPriceFrom $527Free CancellationRating
7.4
9,156 reviews
Search United Airlines flights

  • Copa Airlines Flights From Denver to Panama City

    Copa Airlines is one of the most popular airlines flying from Denver to Panama City, operating 8 flights/week on average for this route. A good Copa Airlines flight deal for Denver to Panama City starts from $464 round-trip, up to an average price of $633. Our users have rated Copa Airlines at 7.6/10.

  • United Airlines Flights From Denver to Panama City

    Another popular option for Denver to Panama City flights is United Airlines (7.4/10, 9,156 ratings). United Airlines flies from Denver to Panama City around 8 times per week, with deals starting from $527 round-trip and rising to an average price of around $683.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Denver to Panama City for you.

Can I find flights from Denver to Panama City with flexible booking policies on momondo?

All flight searches from Denver to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Denver to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Denver. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Denver to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Denver and alert you when they change.

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