Which layover airport has the shortest travel time from Denver to Panama City?

Flights connecting via Houston (IAH) have the shortest average one-way travel time: 7h 44m.

What airlines fly to Panama City?

Copa Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Panama City from Denver according to our data. Copa Airlines is the first choice among our users, with 74% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Denver Intl to Panama City Tocumen Intl?

American Airlines is the most popular carrier operating from Denver Intl to Panama City Tocumen Intl

Which layover airport has the shortest connection time from Denver to Panama City?

Houston (IAH) has the shortest average layover time for this route: 1h 49m.

Which airport is the most popular layover for flights between Denver and Panama City?

Houston (IAH) was the most common stop: 69% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Denver to Panama City?

Flights via Miami (MIA) offer the lowest average round-trip price of $614.

When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?

There are 3 operators available for flights from Denver Intl Airport to Panama City Tocumen Intl Airport as of October 2026.

How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$291 Cheap Flights from Denver to Panama City in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Denver to Panama City

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One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

11:59 pm - 1:26 pmDEN Denver Intl-PTY Panama City Tocumen Intl

11h 27m1 stop Miami

2:26 pm - 10:58 pmPTY Panama City Tocumen Intl-DEN Denver Intl

10h 32m1 stop Miami

$647American Airlines

Tue, Feb 2 - Tue, Feb 9

11:59 pm - 1:26 pmDEN Denver Intl-PTY Panama City Tocumen Intl

11h 27m1 stop Miami

2:47 pm - 11:58 pmPTY Panama City Tocumen Intl-DEN Denver Intl

11h 11m1 stop Miami

$647American Airlines

Tue, Feb 9 - Tue, Feb 23

11:59 pm - 3:55 pmDEN Denver Intl-PTY Panama City Tocumen Intl

13h 56m1 stop Miami

2:26 pm - 10:58 pmPTY Panama City Tocumen Intl-DEN Denver Intl

10h 32m1 stop Miami

$647American Airlines

Thu, Jan 28 - Tue, Feb 2

9:40 pm - 4:15 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 35mnonstop

12:45 pm - 6:04 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 19mnonstop

$649Copa Airlines

Fri, Mar 19 - Mon, Mar 29

9:49 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 44mnonstop

12:56 pm - 5:02 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 06mnonstop

$649Copa Airlines

Sun, Nov 1 - Sat, Nov 7

9:55 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 38mnonstop

12:56 pm - 5:14 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 18mnonstop

$649Copa Airlines

Tue, Feb 2 - Tue, Feb 9

5:00 pm - 12:15 pmDEN Denver Intl-PTY Panama City Tocumen Intl

17h 15m1 stop Atlanta Hartsfield-Jackson

3:20 pm - 11:19 pmPTY Panama City Tocumen Intl-DEN Denver Intl

9h 59m1 stop Atlanta Hartsfield-Jackson

$655Delta

Fri, Jan 15 - Sat, Jan 23

3:35 pm - 12:15 pmDEN Denver Intl-PTY Panama City Tocumen Intl

18h 40m1 stop Atlanta Hartsfield-Jackson

3:20 pm - 11:23 amPTY Panama City Tocumen Intl-DEN Denver Intl

22h 03m1 stop Atlanta Hartsfield-Jackson

$655Delta

Fri, Jan 15 - Mon, Jan 25

5:00 am - 5:12 pmDEN Denver Intl-PTY Panama City Tocumen Intl

10h 12m1 stop Houston George Bush Intcntl

8:55 am - 7:45 pmPTY Panama City Tocumen Intl-DEN Denver Intl

12h 50m1 stop Houston George Bush Intcntl

$752United Airlines

Mon, Feb 1 - Thu, Feb 25

5:00 am - 7:38 pmDEN Denver Intl-PTY Panama City Tocumen Intl

12h 38m1 stop Houston George Bush Intcntl

4:41 pm - 11:27 pmPTY Panama City Tocumen Intl-DEN Denver Intl

8h 46m1 stop Houston George Bush Intcntl

$752United Airlines

Tue, Feb 2 - Tue, Feb 23

Cheap last minute flights

Enter your travel dates to find the best prices.

5:00 pm - 12:59 pmDEN Denver Intl-PTY Panama City Tocumen Intl

18h 59m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:12 pmPTY Panama City Tocumen Intl-DEN Denver Intl

9h 48m1 stop Atlanta Hartsfield-Jackson

$664Delta

Tue, Oct 20 - Thu, Oct 22

3:14 pm - 1:02 pmDEN Denver Intl-PTY Panama City Tocumen Intl

20h 48m2 stops Dallas/Fort Worth Miami

2:02 pm - 10:46 pmPTY Panama City Tocumen Intl-DEN Denver Intl

9h 44m1 stop Miami

$669American Airlines

Tue, Oct 20 - Thu, Oct 22

2:29 pm - 1:02 pmDEN Denver Intl-PTY Panama City Tocumen Intl

21h 33m2 stops Chicago O'Hare Intl Miami

2:02 pm - 11:22 amPTY Panama City Tocumen Intl-DEN Denver Intl

22h 20m2 stops Miami Philadelphia

$669American Airlines

Tue, Oct 20 - Thu, Oct 22

11:53 pm - 1:02 pmDEN Denver Intl-PTY Panama City Tocumen Intl

12h 09m1 stop Miami

2:02 pm - 10:46 pmPTY Panama City Tocumen Intl-DEN Denver Intl

9h 44m1 stop Miami

$735American Airlines

Fri, Oct 16 - Tue, Oct 20

1:53 pm - 6:01 amDEN Denver Intl-PTY Panama City Tocumen Intl

15h 08m1 stop Mexico City Benito Juarez

9:31 pm - 10:46 amPTY Panama City Tocumen Intl-DEN Denver Intl

15h 15m1 stop Mexico City Benito Juarez

$789Multiple Airlines

Wed, Oct 21 - Tue, Nov 10

1:53 pm - 6:01 amDEN Denver Intl-PTY Panama City Tocumen Intl

15h 08m1 stop Mexico City Benito Juarez

9:31 pm - 10:46 amPTY Panama City Tocumen Intl-DEN Denver Intl

15h 15m1 stop Mexico City Benito Juarez

$792Multiple Airlines

Wed, Oct 21 - Fri, Nov 13

5:00 am - 2:14 pmDEN Denver Intl-PTY Panama City Tocumen Intl

8h 14m1 stop Houston George Bush Intcntl

8:55 am - 4:30 pmPTY Panama City Tocumen Intl-DEN Denver Intl

9h 35m1 stop Houston George Bush Intcntl

$894United Airlines

Wed, Oct 21 - Thu, Nov 12

10:07 am - 6:37 pmDEN Denver Intl-PTY Panama City Tocumen Intl

7h 30m1 stop Houston George Bush Intcntl

8:55 am - 7:59 pmPTY Panama City Tocumen Intl-DEN Denver Intl

13h 04m1 stop Houston George Bush Intcntl

$920United Airlines

Wed, Oct 21 - Wed, Nov 11

7:40 am - 6:37 pmDEN Denver Intl-PTY Panama City Tocumen Intl

9h 57m1 stop Houston George Bush Intcntl

10:00 am - 10:15 pmPTY Panama City Tocumen Intl-DEN Denver Intl

13h 15m1 stop Houston George Bush Intcntl

$939United Airlines

Fri, Oct 16 - Tue, Oct 20

10:43 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 50mnonstop

6:40 pm - 10:27 amPTY Panama City Tocumen Intl-DEN Denver Intl

16h 47m1 stop Toronto Pearson Intl

$1,790Copa Airlines

Fri, Oct 16 - Tue, Oct 20

Cheap direct flights

Enter your travel dates to find the best prices.

9:40 pm - 4:15 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 35mnonstop

12:45 pm - 6:04 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 19mnonstop

$649Copa Airlines

Fri, Mar 19 - Mon, Mar 29

9:49 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 44mnonstop

12:56 pm - 5:02 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 06mnonstop

$649Copa Airlines

Sun, Nov 1 - Sat, Nov 7

9:55 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 38mnonstop

12:56 pm - 5:14 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 18mnonstop

$649Copa Airlines

Tue, Feb 2 - Tue, Feb 9

10:43 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 50mnonstop

12:56 pm - 5:02 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 06mnonstop

$649Copa Airlines

Fri, Oct 30 - Sat, Nov 14

9:50 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 43mnonstop

12:56 pm - 5:12 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 16mnonstop

$649Copa Airlines

Mon, Dec 7 - Wed, Jan 20

9:50 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 43mnonstop

12:56 pm - 5:12 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 16mnonstop

$649Copa Airlines

Tue, Jan 19 - Fri, Jan 22

9:49 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 44mnonstop

12:56 pm - 5:02 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 06mnonstop

$4,750United Airlines

Thu, Nov 5 - Fri, Nov 13

9:49 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 44mnonstop

12:56 pm - 5:02 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 06mnonstop

$4,750United Airlines

Thu, Nov 19 - Fri, Nov 27

9:50 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 43mnonstop

12:56 pm - 5:12 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 16mnonstop

$4,750United Airlines

Thu, Jan 14 - Mon, Jan 18

9:49 pm - 5:33 amDEN Denver Intl-PTY Panama City Tocumen Intl

5h 44mnonstop

12:56 pm - 5:10 pmPTY Panama City Tocumen Intl-DEN Denver Intl

6h 14mnonstop

$4,750United Airlines

Thu, Nov 26 - Thu, Dec 3

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American Airlines flights from Denver to Panama City

Our best American Airlines deals on Denver to Panama City flight tickets

American Airlines

Jan 28

DEN11:59 pmDenver Intl

13h 56m

1 stop

PTY3:55 pmPanama City Tocumen Intl

Feb 2

PTY2:26 pmPanama City Tocumen Intl

10h 32m

1 stop

DEN10:58 pmDenver Intl

$647

American Airlines

Jan 28

DEN6:58 pmDenver Intl

16h 28m

2 stops

PTY1:26 pmPanama City Tocumen Intl

Feb 2

PTY2:26 pmPanama City Tocumen Intl

10h 32m

1 stop

DEN10:58 pmDenver Intl

$652

American Airlines

Mar 24

DEN4:28 pmDenver Intl

21h 02m

2 stops

PTY2:30 pmPanama City Tocumen Intl

Mar 31

PTY1:47 pmPanama City Tocumen Intl

11h 11m

1 stop

DEN11:58 pmDenver Intl

$657

Delta flights from Denver to Panama City

Our best Delta deals on Denver to Panama City flight tickets

Delta

Jan 15

DEN5:00 pmDenver Intl

17h 15m

1 stop

PTY12:15 pmPanama City Tocumen Intl

Jan 23

PTY3:20 pmPanama City Tocumen Intl

9h 59m

1 stop

DEN11:19 pmDenver Intl

$655

Delta

Jan 15

DEN5:00 pmDenver Intl

17h 15m

1 stop

PTY12:15 pmPanama City Tocumen Intl

Jan 23

PTY1:40 pmPanama City Tocumen Intl

11h 39m

1 stop

DEN11:19 pmDenver Intl

$664

Delta

Nov 1

DEN8:00 amDenver Intl

27h 59m

1 stop

PTY1:59 pmPanama City Tocumen Intl

Nov 20

PTY3:29 pmPanama City Tocumen Intl

9h 46m

1 stop

DEN11:15 pmDenver Intl

$677

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Tue 2/2

11:59 pm-1:26 pm

1 stop11h 27m

Panama City Tocumen Intl

Tue 2/9

2:26 pm-10:58 pm

1 stop10h 32m

$647

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Tue 2/9

11:59 pm-1:26 pm

1 stop11h 27m

Panama City Tocumen Intl

Tue 2/23

2:47 pm-11:58 pm

1 stop11h 11m

$647

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Thu 1/28

11:59 pm-3:55 pm

1 stop13h 56m

Panama City Tocumen Intl

Tue 2/2

2:26 pm-10:58 pm

1 stop10h 32m

$647

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Fri 3/19

9:40 pm-4:15 am

Nonstop5h 35m

Panama City Tocumen Intl

Mon 3/29

12:45 pm-6:04 pm

Nonstop6h 19m

$649

Quickest round-trip

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Sun 11/1

9:49 pm-5:33 am

Nonstop5h 44m

Panama City Tocumen Intl

Sat 11/7

12:56 pm-5:02 pm

Nonstop6h 06m

$649

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Tue 2/2

9:55 pm-5:33 am

Nonstop5h 38m

Panama City Tocumen Intl

Tue 2/9

12:56 pm-5:14 pm

Nonstop6h 18m

$649

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Fri 1/15

5:00 pm-12:15 pm

1 stop17h 15m

Panama City Tocumen Intl

Sat 1/23

3:20 pm-11:19 pm

1 stop9h 59m

$655

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Fri 1/15

3:35 pm-12:15 pm

1 stop18h 40m

Panama City Tocumen Intl

Mon 1/25

3:20 pm-11:23 am

1 stop22h 03m

$655

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Mon 2/1

5:00 am-5:12 pm

1 stop10h 12m

Panama City Tocumen Intl

Thu 2/25

8:55 am-7:45 pm

1 stop12h 50m

$752

DenverPanama City

DEN Denver Intl - PTY Panama City Tocumen Intl

DENPTY

Denver Intl

Tue 2/2

5:00 am-7:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Tue 2/23

4:41 pm-11:27 pm

1 stop8h 46m

$752

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Denver to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Denver and Panama City?

Prices are currently typical for flights on this route.

Typical prices usually range from $556 to $809.
The lowest price recently found on this route was $647.

What is the cheapest month to fly to Panama City?

In general, April is the cheapest month to fly from Denver to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $598. If you’re not able to fly to Panama City in April, then May is your next best option. Flight prices from Denver to Panama City during May average around $602.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $539. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $653. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

Fly from Denver Intl to Panama City Tocumen Intl for the best Denver Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight from Denver to Panama City?

You are more likely to see cheaper flights to Panama City from Denver when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $681 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Denver for as low as $585 on momondo.

What cabin class options are available on Denver to Panama City flights?

There are 3 cabin classes available to choose from on Denver to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Denver to Panama City flights?

You could potentially save up to 60% on your flight if you consider stops on a Denver to Panama City flight.

How have Denver to Panama City flight prices changed over time?

When to book flights from Denver to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Denver to Panama City according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Denver to Panama City

Best Price Found	$291
Fastest flight time	5h 35m
Direct flights	Mon, Tue, Thu, Fri, Sat and Sun
Airports in Panama City	1 airport

The best one-way flight to Panama City from Denver in the past 72 hours is $291. The best round-trip flight deal from Denver to Panama City found on momondo in the last 72 hours is $647.

The fastest flight from Denver to Panama City takes 5h 35m

Direct flights go from Denver to Panama City on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.

There is 1 airport in Panama City. From Denver there are direct flights to Panama City Tocumen Intl (PTY).

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Frequently asked questions about flying from Denver to Panama City

How far is Denver Intl to Panama City Tocumen Intl by plane?
Panama City Tocumen Intl is 2639.1 mi away from Denver Intl. Flights usually cover this in 5h 35m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?
Prices for flights from Denver Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Denver Intl Airport to Panama City Tocumen Intl Airport?
There are 3 operators available for flights from Denver Intl Airport to Panama City Tocumen Intl Airport as of October 2026.
How old do you have to be to fly from Denver Intl Airport to Panama City Tocumen Intl Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Denver Intl Airport to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Denver to Panama City?
Based on momondo bookings for flights between Denver and Panama City, the leading plane model is Boeing 737-800, making up 63.53% of the total bookings. Other popular models include Boeing 737 MAX 8 with 30.00%, Boeing 737 MAX 9 with 2.35%, and Boeing 737 with 1.18%.
What is the most popular airline from Denver to Panama City?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Denver to Panama City is Copa Airlines (75% of total bookings). The next most popular airlines are United Airlines (22%) and American Airlines (3%).

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $495	Free Cancellation	Rating 7.6 1,549 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $531	Free Cancellation	Rating 7.4 10,365 reviews	Search United Airlines flights
American Airlines	PriceFrom $554	Free Cancellation	Rating 7.0 12,169 reviews	Search American Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Denver to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Denver to Panama City for you.

Can I find flights from Denver to Panama City with flexible booking policies on momondo?

All flight searches from Denver to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Denver to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Denver. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Denver to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Denver and alert you when they change.

An easier way to manage your Panama City trip

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Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from Denver to Panama City from $291

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Denver to Panama City departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Denver to Panama City

Our best American Airlines deals on Denver to Panama City flight tickets

Delta flights from Denver to Panama City

Our best Delta deals on Denver to Panama City flight tickets

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How to get the cheapest flight ticket from Denver to Panama City

What is the typical price of a round-trip flight between Denver and Panama City?

What is the cheapest month to fly to Panama City?

What is the cheapest day to depart on your flight to Panama City?

What is the cheapest Denver Intl to Panama City Tocumen Intl flight route?

How far in advance should I book a flight from Denver to Panama City?

What cabin class options are available on Denver to Panama City flights?

Can stopping save me money on Denver to Panama City flights?

How have Denver to Panama City flight prices changed over time?

What is the cheapest airline that flies from Denver Intl to Panama City Tocumen Intl?

What airlines fly to Panama City?

Which airport is the most popular layover for flights between Denver and Panama City?

Which layover airport offers the lowest fares from Denver to Panama City?

Which layover airport has the shortest travel time from Denver to Panama City?

Which layover airport has the shortest connection time from Denver to Panama City?

When to book flights from Denver to Panama City

Cheap Denver to Panama City (DEN to PTY) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Airports in Panama City

Frequently asked questions about flying from Denver to Panama City

Best airlines flying from Denver to Panama City

Compare and see reviews for airlines that fly from Denver to Panama City with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Airports servicing Panama

Fly your favorite airline to Panama City

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama City

List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Denver

According to popular flight searches on momondo this year

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