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Cheap flights from Cusco to Santiago from $133

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cusco to Santiago departing on 3/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Cusco to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Sky Airline Logo
9:20 pm - 5:50 am
CUZ
-
SCL
7h 30m1 stop
Sky Airline Logo
9:15 pm - 4:15 pm
SCL
-
CUZ
20h 00m1 stop
$256Sky Airline
Mon, Jun 15 - Wed, Jun 17
Multiple Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
Multiple Airlines Logo
9:15 pm - 6:25 am
SCL
-
CUZ
10h 10m1 stop
$277Multiple Airlines
Mon, Jun 15 - Wed, Jun 17
Sky Airline Logo
9:20 pm - 1:45 pm
CUZ
-
SCL
15h 25m1 stop
Sky Airline Logo
12:35 am - 7:20 am
SCL
-
CUZ
31h 45m2 stops
$278Sky Airline
Thu, Apr 9 - Sat, Apr 11
Sky Airline Logo
9:20 pm - 5:50 am
CUZ
-
SCL
7h 30m1 stop
Sky Airline Logo
8:15 pm - 5:50 pm
SCL
-
CUZ
22h 35m1 stop
$279Sky Airline
Thu, Apr 9 - Sun, Apr 12
Multiple Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
Multiple Airlines Logo
8:15 pm - 8:40 pm
SCL
-
CUZ
25h 25m1 stop
$285Multiple Airlines
Thu, Apr 9 - Sun, Apr 12
Multiple Airlines Logo
9:30 am - 2:45 pm
CUZ
-
SCL
3h 15mnonstop
Multiple Airlines Logo
11:05 pm - 6:25 am
SCL
-
CUZ
9h 20m1 stop
$288Multiple Airlines
Wed, Mar 25 - Wed, Mar 25
Multiple Airlines Logo
6:50 am - 3:30 pm
CUZ
-
SCL
6h 40m1 stop
Multiple Airlines Logo
11:05 pm - 7:20 am
SCL
-
CUZ
10h 15m1 stop
$291Multiple Airlines
Wed, Mar 25 - Wed, Mar 25
LATAM Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
LATAM Airlines Logo
2:40 pm - 5:10 pm
SCL
-
CUZ
3h 30mnonstop
$295LATAM Airlines
Mon, Jun 15 - Wed, Jun 17
Sky Airline Logo
4:50 pm - 11:00 am
CUZ
-
SCL
17h 10m2 stops
Sky Airline Logo
9:15 pm - 6:25 am
SCL
-
CUZ
10h 10m1 stop
$296Sky Airline
Mon, Jun 15 - Wed, Jun 17
LATAM Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
LATAM Airlines Logo
7:45 pm - 10:15 pm
SCL
-
CUZ
3h 30mnonstop
$335LATAM Airlines
Thu, Apr 9 - Sun, Apr 12

Sky Airline flights from Cusco to Santiago

Our best Sky Airline deals on Cusco to Santiago flight tickets
Sky Airline
Jun 15
CUZ9:20 pmCusco Velazco Astete
7h 30m
1 stop
SCL5:50 amSantiago Arturo Merino Benitez
Jun 17
SCL9:15 pmSantiago Arturo Merino Benitez
20h 00m
1 stop
CUZ4:15 pmCusco Velazco Astete
$256
Find similar
Sky Airline
Apr 9
CUZ9:20 pmCusco Velazco Astete
15h 25m
1 stop
SCL1:45 pmSantiago Arturo Merino Benitez
Apr 11
SCL12:35 amSantiago Arturo Merino Benitez
31h 45m
2 stops
CUZ7:20 amCusco Velazco Astete
$278
Find similar
Sky Airline
Apr 9
CUZ9:20 pmCusco Velazco Astete
7h 30m
1 stop
SCL5:50 amSantiago Arturo Merino Benitez
Apr 12
SCL8:15 pmSantiago Arturo Merino Benitez
22h 35m
1 stop
CUZ5:50 pmCusco Velazco Astete
$279
Find similar

LATAM Airlines flights from Cusco to Santiago

Our best LATAM Airlines deals on Cusco to Santiago flight tickets
LATAM Airlines
Jun 15
CUZ9:30 amCusco Velazco Astete
3h 20m
SCL1:50 pmSantiago Arturo Merino Benitez
Jun 17
SCL2:40 pmSantiago Arturo Merino Benitez
3h 30m
CUZ5:10 pmCusco Velazco Astete
$295
Find similar
LATAM Airlines
Apr 9
CUZ9:30 amCusco Velazco Astete
3h 20m
SCL1:50 pmSantiago Arturo Merino Benitez
Apr 12
SCL7:45 pmSantiago Arturo Merino Benitez
3h 30m
CUZ10:15 pmCusco Velazco Astete
$335
Find similar
LATAM Airlines
Mar 25
CUZ6:50 amCusco Velazco Astete
6h 40m
1 stop
SCL3:30 pmSantiago Arturo Merino Benitez
Mar 25
SCL7:56 pmSantiago Arturo Merino Benitez
15h 29m
2 stops
CUZ9:25 amCusco Velazco Astete
$490
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cusco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Cusco to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Mon 6/15

9:20 pm-5:50 am

1 stop7h 30m

Santiago Arturo Merino Benitez

Wed 6/17

9:15 pm-4:15 pm

1 stop20h 00m

$256

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Mon 6/15

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

Wed 6/17

9:15 pm-6:25 am

1 stop10h 10m

$277

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

9:20 pm-1:45 pm

1 stop15h 25m

Santiago Arturo Merino Benitez

Sat 4/11

12:35 am-7:20 am

2 stops31h 45m

$278

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

9:20 pm-5:50 am

1 stop7h 30m

Santiago Arturo Merino Benitez

Sun 4/12

8:15 pm-5:50 pm

1 stop22h 35m

$279

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

Sun 4/12

8:15 pm-8:40 pm

1 stop25h 25m

$285

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Wed 3/25

9:30 am-2:45 pm

Nonstop3h 15m

Santiago Arturo Merino Benitez

Wed 3/25

11:05 pm-6:25 am

1 stop9h 20m

$288

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Wed 3/25

6:50 am-3:30 pm

1 stop6h 40m

Santiago Arturo Merino Benitez

Wed 3/25

11:05 pm-7:20 am

1 stop10h 15m

$291

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Mon 6/15

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

Wed 6/17

2:40 pm-5:10 pm

Nonstop3h 30m

$295

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Mon 6/15

4:50 pm-11:00 am

2 stops17h 10m

Santiago Arturo Merino Benitez

Wed 6/17

9:15 pm-6:25 am

1 stop10h 10m

$296

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

Sun 4/12

7:45 pm-10:15 pm

Nonstop3h 30m

$335

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Cusco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Cusco and Santiago?

What is the cheapest month to fly to Santiago?

In general, February is the cheapest month to fly from Cusco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $254. If you don’t want to visit Santiago in February, then you should wait until December to fly from Cusco, when ticket prices are also cheap, with an average price of $276.

What is the cheapest Cusco Velazco Astete to Santiago Arturo Merino Benitez flight route?

Fly from Cusco Velazco Astete to Santiago Arturo Merino Benitez for the best Cusco Velazco Astete - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Cusco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $315 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cusco for as low as $201 on momondo.

What cabin class options are available on Cusco Velazco Astete to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Cusco Velazco Astete to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cusco to Santiago flights?

No. A direct flight is the cheapest option for a flight between Cusco to Santiago.

How have Cusco to Santiago flight prices changed over time?

As of December 2025, prices for Cusco to Santiago flights are approximately 1% cheaper when compared to flights at the same time last year.

When to book flights from Cusco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Cusco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cusco to Santiago (CUZ to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cusco to Santiago

Fastest flight time

3h 15m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sun

Airports in Santiago

1 airport
The fastest flight from Cusco to Santiago takes 3h 15m
Direct flights go from Cusco to Santiago on Monday, Tuesday, Wednesday, Thursday, Friday and Sunday. The only airline offering direct flights is LATAM Airlines.
There is 1 airport in Santiago. From Cusco there are direct flights to Santiago Arturo Merino Benitez (SCL).
Search flight deals

  • How far is Cusco Velazco Astete to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 1377.5 mi away from Cusco Velazco Astete. By plane, this route typically takes 3h 15m.

  • When did momondo last update prices for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cusco to Santiago?

  • What is the most popular airline from Cusco to Santiago?

Best airlines flying from Cusco to Santiago

Compare and see reviews for airlines that fly from Cusco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $280Free CancellationRating
7.5
1,898 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Cusco to Santiago

    The lowest priced LATAM Airlines flight from Cusco to Santiago from the last 72 hours was $280. Generally, LATAM Airlines has 7 flights on this route every week with an average price of $470. LATAM Airlines is rated 7.5/10 by our users.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Cusco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Cusco.

Can I find flights from Cusco to Santiago with flexible booking policies on momondo?

Yes. All flights to Santiago from Cusco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Cusco to Santiago?

Once you have performed a search for Cusco to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Cusco to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Cusco to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.

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