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Cheap flights from Cusco to Santiago from $137

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cusco to Santiago departing on 12/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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JetSMART Logo
7:02 am - 8:31 pmCUZ-SCL
11h 29m1 stop
JetSMART Logo
6:01 am - 11:59 amSCL-CUZ
7h 58m1 stop
$247JetSMART
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Thu, Mar 19 - Wed, Mar 25
Multiple Airlines Logo
7:02 am - 8:31 pmCUZ-SCL
11h 29m1 stop
Multiple Airlines Logo
1:35 am - 4:05 pmSCL-CUZ
16h 30m2 stops
$252Multiple Airlines
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Thu, Mar 19 - Tue, Mar 24
Multiple Airlines Logo
2:40 pm - 7:55 pmCUZ-SCL
3h 15mnonstop
Multiple Airlines Logo
5:59 am - 4:51 pmSCL-CUZ
12h 52m1 stop
$262Multiple Airlines
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Fri, Oct 31 - Sun, Nov 2
Sky Airline Logo
12:05 pm - 9:15 pmCUZ-SCL
8h 10m1 stop
Sky Airline Logo
1:55 am - 5:50 pmSCL-CUZ
16h 55m2 stops
$295Sky Airline
Find Deal
Sun, Apr 5 - Tue, Apr 7
LATAM Airlines Logo
12:05 am - 5:45 pmCUZ-SCL
15h 40m1 stop
LATAM Airlines Logo
5:40 am - 12:40 pmSCL-CUZ
9h 00m1 stop
$301LATAM Airlines
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Thu, Oct 30 - Sun, Nov 2
Sky Airline Logo
8:30 pm - 12:15 pmCUZ-SCL
13h 45m2 stops
Sky Airline Logo
1:35 am - 4:05 pmSCL-CUZ
16h 30m2 stops
$331Sky Airline
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Fri, Nov 28 - Thu, Dec 4
LATAM Airlines Logo
9:30 am - 2:45 pmCUZ-SCL
3h 15mnonstop
LATAM Airlines Logo
3:45 pm - 5:15 pmSCL-CUZ
3h 30mnonstop
$339LATAM Airlines
Find Deal
Thu, Mar 19 - Wed, Mar 25
Aerolineas Argentinas Logo
7:00 pm - 9:25 amCUZ-SCL
12h 25m2 stops
Aerolineas Argentinas Logo
10:15 am - 11:25 pmSCL-CUZ
15h 10m2 stops
$534Aerolineas Argentinas
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Thu, Mar 19 - Wed, Mar 25
Avianca Logo
5:10 pm - 3:20 pmCUZ-SCL
20h 10m1 stop
Avianca Logo
4:25 pm - 11:20 amSCL-CUZ
20h 55m1 stop
$553Avianca
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Mon, Dec 1 - Tue, Dec 9
Avianca Logo
5:10 pm - 3:20 pmCUZ-SCL
20h 10m1 stop
Avianca Logo
1:35 am - 11:20 amSCL-CUZ
11h 45m1 stop
$592Avianca
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Mon, Dec 1 - Mon, Dec 8

Avianca flights from Cusco to Santiago

Our best Avianca deals on Cusco to Santiago flight tickets
Avianca
Dec 1
CUZ5:10 pmCusco Velazco Astete
20h 10m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Dec 9
SCL4:25 pmSantiago Arturo Merino Benitez
20h 55m
1 stop
CUZ11:20 amCusco Velazco Astete
$553
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Avianca
Dec 1
CUZ5:10 pmCusco Velazco Astete
20h 10m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Dec 8
SCL1:35 amSantiago Arturo Merino Benitez
11h 45m
1 stop
CUZ11:20 amCusco Velazco Astete
$592
Find similar
Avianca
Dec 1
CUZ5:10 pmCusco Velazco Astete
20h 10m
1 stop
SCL3:20 pmSantiago Arturo Merino Benitez
Dec 7
SCL1:35 amSantiago Arturo Merino Benitez
11h 45m
1 stop
CUZ11:20 amCusco Velazco Astete
$657
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Sky Airline flights from Cusco to Santiago

Our best Sky Airline deals on Cusco to Santiago flight tickets
Sky Airline
Apr 5
CUZ12:05 pmCusco Velazco Astete
8h 10m
1 stop
SCL9:15 pmSantiago Arturo Merino Benitez
Apr 7
SCL1:55 amSantiago Arturo Merino Benitez
16h 55m
2 stops
CUZ5:50 pmCusco Velazco Astete
$295
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Sky Airline
Oct 22
CUZ12:05 pmCusco Velazco Astete
22h 15m
2 stops
SCL12:20 pmSantiago Arturo Merino Benitez
Oct 25
SCL9:05 pmSantiago Arturo Merino Benitez
12h 15m
1 stop
CUZ7:20 amCusco Velazco Astete
$307
Find similar
Sky Airline
Nov 28
CUZ8:30 pmCusco Velazco Astete
13h 45m
2 stops
SCL12:15 pmSantiago Arturo Merino Benitez
Dec 4
SCL1:35 amSantiago Arturo Merino Benitez
16h 30m
2 stops
CUZ4:05 pmCusco Velazco Astete
$331
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momondo Fare Finder

 
Customize your flight search to find flights from Cusco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Cusco to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 3/19

7:02 am-8:31 pm

1 stop11h 29m

Santiago Arturo Merino Benitez

Wed 3/25

6:01 am-11:59 am

1 stop7h 58m

$247

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 3/19

7:02 am-8:31 pm

1 stop11h 29m

Santiago Arturo Merino Benitez

Tue 3/24

1:35 am-4:05 pm

2 stops16h 30m

$252

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 10/31

2:40 pm-7:55 pm

Nonstop3h 15m

Santiago Arturo Merino Benitez

Sun 11/2

5:59 am-4:51 pm

1 stop12h 52m

$262

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Sun 4/5

12:05 pm-9:15 pm

1 stop8h 10m

Santiago Arturo Merino Benitez

Tue 4/7

1:55 am-5:50 pm

2 stops16h 55m

$295

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 10/30

12:05 am-5:45 pm

1 stop15h 40m

Santiago Arturo Merino Benitez

Sun 11/2

5:40 am-12:40 pm

1 stop9h 00m

$301

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 11/28

8:30 pm-12:15 pm

2 stops13h 45m

Santiago Arturo Merino Benitez

Thu 12/4

1:35 am-4:05 pm

2 stops16h 30m

$331

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 3/19

9:30 am-2:45 pm

Nonstop3h 15m

Santiago Arturo Merino Benitez

Wed 3/25

3:45 pm-5:15 pm

Nonstop3h 30m

$339

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 3/19

7:00 pm-9:25 am

2 stops12h 25m

Santiago Arturo Merino Benitez

Wed 3/25

10:15 am-11:25 pm

2 stops15h 10m

$534

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Mon 12/1

5:10 pm-3:20 pm

1 stop20h 10m

Santiago Arturo Merino Benitez

Tue 12/9

4:25 pm-11:20 am

1 stop20h 55m

$553

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Mon 12/1

5:10 pm-3:20 pm

1 stop20h 10m

Santiago Arturo Merino Benitez

Mon 12/8

1:35 am-11:20 am

1 stop11h 45m

$592

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Santiago from

How to get the cheapest flight ticket from Cusco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Cusco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $246. If you don’t want to visit Santiago in October, then you should wait until February to fly from Cusco, when ticket prices are also cheap, with an average price of $272.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Cusco to Santiago when you can find flight prices for as low as $469. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $470 per ticket.

What is the cheapest Cusco Velazco Astete to Santiago Arturo Merino Benitez flight route?

Fly from Cusco Velazco Astete to Santiago Arturo Merino Benitez for the best Cusco Velazco Astete - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Cusco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $317 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cusco for as low as $161 on momondo.

What cabin class options are available on Cusco Velazco Astete to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Cusco Velazco Astete to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cusco to Santiago flights?

You could potentially save up to 24% on your flight if you consider stops on a Cusco to Santiago flight.

How have Cusco to Santiago flight prices changed over time?

As of October 2025, prices for Cusco to Santiago flights are approximately 8% cheaper when compared to flights at the same time last year.

When to book flights from Cusco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Cusco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cusco to Santiago (CUZ to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cusco to Santiago

Fastest flight time

3h 15m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in Santiago

1 airport
The fastest flight from Cusco to Santiago takes 3h 15m
Direct flights go from Cusco to Santiago on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is LATAM Airlines.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Cusco Velazco Astete to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 1377.5 mi away from Cusco Velazco Astete. By plane, this route typically takes 3h 15m.

  • When did momondo last update prices for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cusco to Santiago?

  • What is the most popular airline from Cusco to Santiago?

Best airlines flying from Cusco to Santiago

Compare and see reviews for airlines that fly from Cusco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $292Free CancellationRating
7.5
1,866 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Cusco to Santiago

    The lowest priced LATAM Airlines flight from Cusco to Santiago from the last 72 hours was $292. Generally, LATAM Airlines has 6 flights on this route every week with an average price of $469. LATAM Airlines is rated 7.5/10 by our users.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Cusco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Cusco.

Can I find flights from Cusco to Santiago with flexible booking policies on momondo?

Yes. All flights to Santiago from Cusco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Cusco to Santiago?

Once you have performed a search for Cusco to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Cusco to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Cusco to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.

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