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Cheap flights from Cusco to Santiago from $112

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cusco to Santiago departing on 5/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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JetSMART Logo
4:42 pm - 4:01 amCUZ-SCL
10h 19m1 stop
JetSMART Logo
4:51 am - 8:19 pmSCL-CUZ
16h 28m1 stop
$229JetSMART
Find Deal
Thu, Apr 9 - Sun, Apr 12
JetSMART Logo
4:42 pm - 4:01 amCUZ-SCL
10h 19m1 stop
JetSMART Logo
4:51 am - 9:49 pmSCL-CUZ
17h 58m1 stop
$233JetSMART
Find Deal
Thu, Apr 9 - Sun, Apr 12
JetSMART Logo
5:17 pm - 4:01 amCUZ-SCL
9h 44m1 stop
JetSMART Logo
4:51 am - 4:44 pmSCL-CUZ
12h 53m1 stop
$240JetSMART
Find Deal
Fri, May 29 - Sun, May 31
Multiple Airlines Logo
7:05 am - 11:15 amCUZ-SCL
27h 10m2 stops
Multiple Airlines Logo
4:51 am - 3:39 pmSCL-CUZ
11h 48m1 stop
$246Multiple Airlines
Find Deal
Thu, Apr 9 - Sun, Apr 12
Sky Airline Logo
11:10 am - 11:15 amCUZ-SCL
23h 05m2 stops
Sky Airline Logo
4:55 am - 4:15 pmSCL-CUZ
12h 20m1 stop
$257Sky Airline
Find Deal
Thu, Apr 9 - Sun, Apr 12
Sky Airline Logo
9:20 pm - 1:45 pmCUZ-SCL
15h 25m1 stop
Sky Airline Logo
12:35 am - 5:50 pmSCL-CUZ
18h 15m2 stops
$260Sky Airline
Find Deal
Thu, Apr 9 - Sat, Apr 11
Multiple Airlines Logo
9:30 am - 1:50 pmCUZ-SCL
3h 20mnonstop
Multiple Airlines Logo
4:51 am - 11:04 amSCL-CUZ
7h 13m1 stop
$262Multiple Airlines
Find Deal
Thu, Apr 9 - Sun, Apr 12
LATAM Airlines Logo
9:30 am - 2:45 pmCUZ-SCL
3h 15mnonstop
LATAM Airlines Logo
4:15 pm - 9:25 pmSCL-CUZ
7h 10m1 stop
$266LATAM Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 22
Sky Airline Logo
11:10 am - 11:15 amCUZ-SCL
23h 05m2 stops
Sky Airline Logo
8:15 pm - 7:20 amSCL-CUZ
12h 05m1 stop
$267Sky Airline
Find Deal
Thu, Apr 9 - Sun, Apr 12
Sky Airline Logo
11:10 am - 11:15 amCUZ-SCL
23h 05m2 stops
Sky Airline Logo
12:35 am - 5:50 pmSCL-CUZ
18h 15m2 stops
$271Sky Airline
Find Deal
Thu, Apr 9 - Sat, Apr 11

JetSMART flights from Cusco to Santiago

Our best JetSMART deals on Cusco to Santiago flight tickets
JetSMART
Apr 9
CUZ4:42 pmCusco Velazco Astete
10h 19m
1 stop
SCL4:01 amSantiago Arturo Merino Benitez
Apr 12
SCL4:51 amSantiago Arturo Merino Benitez
16h 28m
1 stop
CUZ8:19 pmCusco Velazco Astete
$229
Find similar
JetSMART
Apr 9
CUZ4:42 pmCusco Velazco Astete
10h 19m
1 stop
SCL4:01 amSantiago Arturo Merino Benitez
Apr 12
SCL4:51 amSantiago Arturo Merino Benitez
17h 58m
1 stop
CUZ9:49 pmCusco Velazco Astete
$233
Find similar
JetSMART
May 29
CUZ5:17 pmCusco Velazco Astete
9h 44m
1 stop
SCL4:01 amSantiago Arturo Merino Benitez
May 31
SCL4:51 amSantiago Arturo Merino Benitez
12h 53m
1 stop
CUZ4:44 pmCusco Velazco Astete
$240
Find similar

Sky Airline flights from Cusco to Santiago

Our best Sky Airline deals on Cusco to Santiago flight tickets
Sky Airline
Apr 9
CUZ11:10 amCusco Velazco Astete
23h 05m
2 stops
SCL11:15 amSantiago Arturo Merino Benitez
Apr 12
SCL4:55 amSantiago Arturo Merino Benitez
12h 20m
1 stop
CUZ4:15 pmCusco Velazco Astete
$257
Find similar
Sky Airline
Apr 9
CUZ9:20 pmCusco Velazco Astete
15h 25m
1 stop
SCL1:45 pmSantiago Arturo Merino Benitez
Apr 11
SCL12:35 amSantiago Arturo Merino Benitez
18h 15m
2 stops
CUZ5:50 pmCusco Velazco Astete
$260
Find similar
Sky Airline
Apr 9
CUZ11:10 amCusco Velazco Astete
23h 05m
2 stops
SCL11:15 amSantiago Arturo Merino Benitez
Apr 11
SCL12:35 amSantiago Arturo Merino Benitez
18h 15m
2 stops
CUZ5:50 pmCusco Velazco Astete
$271
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cusco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Cusco to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

4:42 pm-4:01 am

1 stop10h 19m

Santiago Arturo Merino Benitez

Sun 4/12

4:51 am-8:19 pm

1 stop16h 28m

$229

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

4:42 pm-4:01 am

1 stop10h 19m

Santiago Arturo Merino Benitez

Sun 4/12

4:51 am-9:49 pm

1 stop17h 58m

$233

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Fri 5/29

5:17 pm-4:01 am

1 stop9h 44m

Santiago Arturo Merino Benitez

Sun 5/31

4:51 am-4:44 pm

1 stop12h 53m

$240

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

7:05 am-11:15 am

2 stops27h 10m

Santiago Arturo Merino Benitez

Sun 4/12

4:51 am-3:39 pm

1 stop11h 48m

$246

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

11:10 am-11:15 am

2 stops23h 05m

Santiago Arturo Merino Benitez

Sun 4/12

4:55 am-4:15 pm

1 stop12h 20m

$257

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

9:20 pm-1:45 pm

1 stop15h 25m

Santiago Arturo Merino Benitez

Sat 4/11

12:35 am-5:50 pm

2 stops18h 15m

$260

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

Sun 4/12

4:51 am-11:04 am

1 stop7h 13m

$262

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 1/15

9:30 am-2:45 pm

Nonstop3h 15m

Santiago Arturo Merino Benitez

Thu 1/22

4:15 pm-9:25 pm

1 stop7h 10m

$266

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

11:10 am-11:15 am

2 stops23h 05m

Santiago Arturo Merino Benitez

Sun 4/12

8:15 pm-7:20 am

1 stop12h 05m

$267

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

Thu 4/9

11:10 am-11:15 am

2 stops23h 05m

Santiago Arturo Merino Benitez

Sat 4/11

12:35 am-5:50 pm

2 stops18h 15m

$271

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Cusco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Cusco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $248. If you don’t want to visit Santiago in October, then you should wait until February to fly from Cusco, when ticket prices are also cheap, with an average price of $251.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from Cusco to Santiago when you can find flight prices for as low as $414. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $469 per ticket.

What is the cheapest Cusco Velazco Astete to Santiago Arturo Merino Benitez flight route?

Fly from Cusco Velazco Astete to Santiago Arturo Merino Benitez for the best Cusco Velazco Astete - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Cusco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $315 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cusco for as low as $161 on momondo.

What cabin class options are available on Cusco Velazco Astete to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Cusco Velazco Astete to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cusco to Santiago flights?

No. A direct flight is the cheapest option for a flight between Cusco to Santiago.

How have Cusco to Santiago flight prices changed over time?

As of December 2025, prices for Cusco to Santiago flights are approximately 5% cheaper when compared to flights at the same time last year.

When to book flights from Cusco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Cusco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cusco to Santiago (CUZ to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cusco to Santiago

Fastest flight time

3h 15m

Direct flights

Every day

Airports in Santiago

1 airport
The fastest flight from Cusco to Santiago takes 3h 15m
Direct flights go from Cusco to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Cusco Velazco Astete to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 1377.5 mi away from Cusco Velazco Astete. By plane, this route typically takes 3h 15m.

  • When did momondo last update prices for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How many operators does momondo search for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cusco to Santiago?

  • What is the most popular airline from Cusco to Santiago?

Best airlines flying from Cusco to Santiago

Compare and see reviews for airlines that fly from Cusco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
LATAM AirlinesPriceFrom $317Free CancellationRating
7.5
1,890 reviews
Search LATAM Airlines flights

  • LATAM Airlines Flights From Cusco to Santiago

    The lowest priced LATAM Airlines flight from Cusco to Santiago from the last 72 hours was $317. Generally, LATAM Airlines has 6 flights on this route every week with an average price of $469. LATAM Airlines is rated 7.5/10 by our users.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Cusco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Cusco.

Can I find flights from Cusco to Santiago with flexible booking policies on momondo?

Yes. All flights to Santiago from Cusco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Cusco to Santiago?

Once you have performed a search for Cusco to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Cusco to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Cusco to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.

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