Cheap flights from Cusco to Santiago from $162

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cusco to Santiago departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

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Sky Airline Logo
9:40 pm - 1:30 pm
CUZ
-
SCL
14h 50m
1 stop
Sky Airline Logo
12:40 am - 4:00 pm
SCL
-
CUZ
16h 20m
2 stops
$324Sky Airline
ons, maj 20 - tis, maj 26
Sky Airline Logo
9:45 pm - 1:30 pm
CUZ
-
SCL
14h 45m
1 stop
Sky Airline Logo
12:55 am - 6:10 am
SCL
-
CUZ
30h 15m
2 stops
$334Sky Airline
tors, maj 21 - ons, maj 27
Multiple Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
Multiple Airlines Logo
8:20 pm - 1:35 pm
SCL
-
CUZ
18h 15m
1 stop
$342Multiple Airlines
fre, apr 24 - mån, apr 27
Sky Airline Logo
6:50 am - 11:05 am
CUZ
-
SCL
27h 15m
2 stops
Sky Airline Logo
8:20 pm - 11:30 am
SCL
-
CUZ
16h 10m
1 stop
$344Sky Airline
fre, apr 24 - mån, apr 27
Multiple Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
Multiple Airlines Logo
8:20 pm - 5:00 pm
SCL
-
CUZ
21h 40m
1 stop
$345Multiple Airlines
fre, apr 24 - mån, apr 27
LATAM Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
LATAM Airlines Logo
2:40 pm - 5:10 pm
SCL
-
CUZ
3h 30mnonstop
$346LATAM Airlines
tors, maj 21 - tors, maj 28
Multiple Airlines Logo
2:15 pm - 1:30 pm
CUZ
-
SCL
22h 15m
1 stop
Multiple Airlines Logo
2:40 pm - 5:10 pm
SCL
-
CUZ
3h 30mnonstop
$347Multiple Airlines
ons, maj 13 - ons, maj 20
LATAM Airlines Logo
9:30 am - 1:50 pm
CUZ
-
SCL
3h 20mnonstop
LATAM Airlines Logo
2:40 pm - 5:10 pm
SCL
-
CUZ
3h 30mnonstop
$349LATAM Airlines
fre, apr 24 - mån, apr 27
Sky Airline Logo
6:50 am - 11:05 am
CUZ
-
SCL
27h 15m
2 stops
Sky Airline Logo
12:40 am - 8:35 am
SCL
-
CUZ
32h 55m
2 stops
$350Sky Airline
fre, apr 24 - sön, apr 26
Sky Airline Logo
6:50 am - 11:05 am
CUZ
-
SCL
27h 15m
2 stops
Sky Airline Logo
12:40 am - 4:00 pm
SCL
-
CUZ
16h 20m
2 stops
$351Sky Airline
ons, maj 20 - tis, maj 26

LATAM Airlines flights from Cusco to Santiago

Our best LATAM Airlines deals on Cusco to Santiago flight tickets
LATAM Airlines
May 21
CUZ9:30 amCusco Velazco Astete
3h 20m
SCL1:50 pmSantiago Arturo Merino Benitez
May 28
SCL2:40 pmSantiago Arturo Merino Benitez
3h 30m
CUZ5:10 pmCusco Velazco Astete
$346
LATAM Airlines
Apr 24
CUZ9:30 amCusco Velazco Astete
3h 20m
SCL1:50 pmSantiago Arturo Merino Benitez
Apr 27
SCL2:40 pmSantiago Arturo Merino Benitez
3h 30m
CUZ5:10 pmCusco Velazco Astete
$349
LATAM Airlines
Apr 9
CUZ9:30 amCusco Velazco Astete
3h 20m
SCL1:50 pmSantiago Arturo Merino Benitez
Apr 12
SCL7:45 pmSantiago Arturo Merino Benitez
3h 30m
CUZ10:15 pmCusco Velazco Astete
$359

Sky Airline flights from Cusco to Santiago

Our best Sky Airline deals on Cusco to Santiago flight tickets
Sky Airline
May 20
CUZ9:40 pmCusco Velazco Astete
14h 50m
1 stop
SCL1:30 pmSantiago Arturo Merino Benitez
May 26
SCL12:40 amSantiago Arturo Merino Benitez
16h 20m
2 stops
CUZ4:00 pmCusco Velazco Astete
$324
Sky Airline
May 21
CUZ9:45 pmCusco Velazco Astete
14h 45m
1 stop
SCL1:30 pmSantiago Arturo Merino Benitez
May 27
SCL12:55 amSantiago Arturo Merino Benitez
30h 15m
2 stops
CUZ6:10 amCusco Velazco Astete
$334
Sky Airline
Apr 24
CUZ6:50 amCusco Velazco Astete
27h 15m
2 stops
SCL11:05 amSantiago Arturo Merino Benitez
Apr 27
SCL8:20 pmSantiago Arturo Merino Benitez
16h 10m
1 stop
CUZ11:30 amCusco Velazco Astete
$344

momondo Fare Finder

 
Customize your flight search to find flights from Cusco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated april 6, 2026.
Use the filters below to find and compare flights from Cusco to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

ons 5/20

9:40 pm-1:30 pm

1 stop14h 50m

Santiago Arturo Merino Benitez

tis 5/26

12:40 am-4:00 pm

2 stops16h 20m

$324

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

tors 5/21

9:45 pm-1:30 pm

1 stop14h 45m

Santiago Arturo Merino Benitez

ons 5/27

12:55 am-6:10 am

2 stops30h 15m

$334

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

fre 4/24

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

mån 4/27

8:20 pm-1:35 pm

1 stop18h 15m

$342

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

fre 4/24

6:50 am-11:05 am

2 stops27h 15m

Santiago Arturo Merino Benitez

mån 4/27

8:20 pm-11:30 am

1 stop16h 10m

$344

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

fre 4/24

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

mån 4/27

8:20 pm-5:00 pm

1 stop21h 40m

$345
Quickest round-trip

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

tors 5/21

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

tors 5/28

2:40 pm-5:10 pm

Nonstop3h 30m

$346

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

ons 5/13

2:15 pm-1:30 pm

1 stop22h 15m

Santiago Arturo Merino Benitez

ons 5/20

2:40 pm-5:10 pm

Nonstop3h 30m

$347

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

fre 4/24

9:30 am-1:50 pm

Nonstop3h 20m

Santiago Arturo Merino Benitez

mån 4/27

2:40 pm-5:10 pm

Nonstop3h 30m

$349

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

fre 4/24

6:50 am-11:05 am

2 stops27h 15m

Santiago Arturo Merino Benitez

sön 4/26

12:40 am-8:35 am

2 stops32h 55m

$350

CuscoSantiago

CUZ - SCL

CUZSCL

Cusco Velazco Astete

ons 5/20

6:50 am-11:05 am

2 stops27h 15m

Santiago Arturo Merino Benitez

tis 5/26

12:40 am-4:00 pm

2 stops16h 20m

$351

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Cusco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Cusco and Santiago?

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from Cusco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $177. If you don’t want to visit Santiago in October, then you should wait until December to fly from Cusco, when ticket prices are also cheap, with an average price of $242.

What is the cheapest Cusco Velazco Astete to Santiago Arturo Merino Benitez flight route?

Fly from Cusco Velazco Astete to Santiago Arturo Merino Benitez for the best Cusco Velazco Astete - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Cusco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $311 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Cusco for as low as $183 on momondo.

What cabin class options are available on Cusco Velazco Astete to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Cusco Velazco Astete to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cusco to Santiago flights?

No. A direct flight is the cheapest option for a flight between Cusco to Santiago.

How have Cusco to Santiago flight prices changed over time?

As of April 2026, prices for Cusco to Santiago flights are approximately 13% cheaper when compared to flights at the same time last year.

When to book flights from Cusco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Cusco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cusco to Santiago (CUZ to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cusco to Santiago

Fastest flight time

3h 20m

Direct flights

Every day

Airports in Santiago

1 airport
The fastest flight from Cusco to Santiago takes 3h 20m
Direct flights go from Cusco to Santiago every day.
There is 1 airport in Santiago. From Cusco there are direct flights to Santiago Arturo Merino Benitez (SCL).

Frequently asked questions about flying from Cusco to Santiago

  • How far is Cusco Velazco Astete to Santiago Arturo Merino Benitez by plane?

    Santiago Arturo Merino Benitez is 1377.5 mi away from Cusco Velazco Astete. By plane, this route typically takes 3h 20m.

  • When did momondo last update prices for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport refresh daily.

  • How old do you have to be to fly from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cusco Velazco Astete Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cusco to Santiago?

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Cusco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Cusco.

Can I find flights from Cusco to Santiago with flexible booking policies on momondo?

Yes. All flights to Santiago from Cusco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Cusco to Santiago?

Once you have performed a search for Cusco to Santiago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Cusco to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Cusco to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.

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1 adult
ons 5/6
ons 5/13

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