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Cheap flights from Charleston to Panama City from $194

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charleston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 2:20 pm
CHS
-
PTY
9h 20m
1 stop
American Airlines Logo
3:10 pm - 11:59 pm
PTY
-
CHS
7h 49m
1 stop
$401American Airlines
Di, Mrz 17 - Do, Mrz 26
American Airlines Logo
6:45 pm - 2:20 pm
CHS
-
PTY
20h 35m
2 stops
American Airlines Logo
1:40 pm - 11:59 pm
PTY
-
CHS
9h 19m
1 stop
$405American Airlines
Mi, Mrz 11 - Mi, Mrz 18
American Airlines Logo
8:09 pm - 12:46 pm
CHS
-
PTY
17h 37m
1 stop
American Airlines Logo
1:49 pm - 12:24 am
PTY
-
CHS
9h 35m
1 stop
$409American Airlines
Mo, Apr 20 - Mi, Apr 22
American Airlines Logo
6:00 am - 2:20 pm
CHS
-
PTY
9h 20m
1 stop
American Airlines Logo
3:10 pm - 11:59 pm
PTY
-
CHS
7h 49m
1 stop
$418American Airlines
Mi, Mrz 11 - Mi, Mrz 18
American Airlines Logo
6:45 pm - 12:40 pm
CHS
-
PTY
18h 55m
2 stops
American Airlines Logo
3:10 pm - 1:53 pm
PTY
-
CHS
21h 43m
2 stops
$420American Airlines
Di, Mrz 17 - Do, Mrz 26
American Airlines Logo
6:45 pm - 2:20 pm
CHS
-
PTY
20h 35m
2 stops
American Airlines Logo
1:40 pm - 11:16 am
PTY
-
CHS
20h 36m
2 stops
$425American Airlines
Sa, Mrz 14 - Di, Mrz 17
American Airlines Logo
8:08 pm - 2:20 pm
CHS
-
PTY
19h 12m
1 stop
American Airlines Logo
3:10 pm - 11:59 pm
PTY
-
CHS
7h 49m
1 stop
$429American Airlines
Sa, Mrz 14 - Di, Mrz 17
United Airlines Logo
7:00 am - 6:37 pm
CHS
-
PTY
12h 37m
1 stop
United Airlines Logo
7:55 am - 10:12 pm
PTY
-
CHS
13h 17m
1 stop
$431United Airlines
Sa, Jun 6 - So, Jun 14
American Airlines Logo
6:45 pm - 3:01 pm
CHS
-
PTY
21h 16m
2 stops
American Airlines Logo
1:49 pm - 12:26 pm
PTY
-
CHS
21h 37m
2 stops
$437American Airlines
Mi, Apr 1 - Di, Apr 7
United Airlines Logo
7:00 am - 2:14 pm
CHS
-
PTY
8h 14m
1 stop
United Airlines Logo
7:55 am - 10:12 pm
PTY
-
CHS
13h 17m
1 stop
$441United Airlines
Sa, Jun 6 - So, Jun 14

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets
United Airlines
Jun 6
CHS7:00 amCharleston
12h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jun 14
PTY7:55 amPanama City Tocumen Intl
13h 17m
1 stop
CHS10:12 pmCharleston
$431
United Airlines
Jun 6
CHS7:00 amCharleston
8h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Jun 14
PTY7:55 amPanama City Tocumen Intl
13h 17m
1 stop
CHS10:12 pmCharleston
$441
United Airlines
Mar 7
CHS7:01 pmCharleston
10h 09m
1 stop
PTY5:10 amPanama City Tocumen Intl
Mar 9
PTY3:41 pmPanama City Tocumen Intl
23h 27m
1 stop
CHS4:08 pmCharleston
$451

American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets
American Airlines
Mar 17
CHS6:00 amCharleston
9h 20m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Mar 26
PTY3:10 pmPanama City Tocumen Intl
7h 49m
1 stop
CHS11:59 pmCharleston
$401
American Airlines
Mar 11
CHS6:45 pmCharleston
20h 35m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 18
PTY1:40 pmPanama City Tocumen Intl
9h 19m
1 stop
CHS11:59 pmCharleston
$405
American Airlines
Apr 20
CHS8:09 pmCharleston
17h 37m
1 stop
PTY12:46 pmPanama City Tocumen Intl
Apr 22
PTY1:49 pmPanama City Tocumen Intl
9h 35m
1 stop
CHS12:24 amCharleston
$409

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated Februar 11, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Di 3/17

6:00 am-2:20 pm

1 stop9h 20m

Panama City Tocumen Intl

Do 3/26

3:10 pm-11:59 pm

1 stop7h 49m

$401

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mi 3/11

6:45 pm-2:20 pm

2 stops20h 35m

Panama City Tocumen Intl

Mi 3/18

1:40 pm-11:59 pm

1 stop9h 19m

$405

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mo 4/20

8:09 pm-12:46 pm

1 stop17h 37m

Panama City Tocumen Intl

Mi 4/22

1:49 pm-12:24 am

1 stop9h 35m

$409

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mi 3/11

6:00 am-2:20 pm

1 stop9h 20m

Panama City Tocumen Intl

Mi 3/18

3:10 pm-11:59 pm

1 stop7h 49m

$418

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Di 3/17

6:45 pm-12:40 pm

2 stops18h 55m

Panama City Tocumen Intl

Do 3/26

3:10 pm-1:53 pm

2 stops21h 43m

$420

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sa 3/14

6:45 pm-2:20 pm

2 stops20h 35m

Panama City Tocumen Intl

Di 3/17

1:40 pm-11:16 am

2 stops20h 36m

$425

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sa 3/14

8:08 pm-2:20 pm

1 stop19h 12m

Panama City Tocumen Intl

Di 3/17

3:10 pm-11:59 pm

1 stop7h 49m

$429

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sa 6/6

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

So 6/14

7:55 am-10:12 pm

1 stop13h 17m

$431

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mi 4/1

6:45 pm-3:01 pm

2 stops21h 16m

Panama City Tocumen Intl

Di 4/7

1:49 pm-12:26 pm

2 stops21h 37m

$437

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sa 6/6

7:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

So 6/14

7:55 am-10:12 pm

1 stop13h 17m

$441

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $373. If you’re not able to fly to Panama City in March, then September is your next best option. Flight prices from Charleston to Panama City during September average around $389.

Can stopping save me money on Charleston to Panama City flights?

You could potentially save up to 2% on your flight if you consider stops on a Charleston to Panama City flight.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Fastest flight time

7h 40m

Direct flights

None
The fastest flight from Charleston to Panama City takes 7h 40m
There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.
Search flight deals

  • How far is Charleston to Panama City Tocumen Intl by plane?

    The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 7h 40m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Panama City?

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $309Free CancellationRating
7.9
8,179 reviews
Search Delta flights
American AirlinesPriceFrom $363Free CancellationRating
7.2
11,267 reviews
Search American Airlines flights
United AirlinesPriceFrom $369Free CancellationRating
7.4
9,276 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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