What airlines fly to Panama City?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama City from Charleston according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Charleston to Panama City Tocumen Intl?

American Airlines and United Airlines are the most popular carriers operating from Charleston to Panama City Tocumen Intl

Which airport is the most popular layover for flights between Charleston and Panama City?

Miami (MIA) was the most common stop: 75% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Charleston to Panama City?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 7h 44m.

Which layover airport offers the lowest fares from Charleston to Panama City?

Flights via Houston (IAH) offer the lowest average round-trip price of $682.

Which layover airport has the shortest connection time from Charleston to Panama City?

Miami (MIA) has the shortest average layover time for this route: 2h 53m.

When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

As of October 2026, there are 3 operators available to choose from for flights from Charleston Airport to Panama City Tocumen Intl Airport.

How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$277 Cheap Flights from Charleston to Panama City in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to Panama City

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:21 am - 2:34 pmCHS Charleston-PTY Panama City Tocumen Intl

7h 13m1 stop Miami

3:13 pm - 10:13 pmPTY Panama City Tocumen Intl-CHS Charleston

7h 00m1 stop Miami

$627American Airlines

Fri, Nov 27 - Wed, Dec 2

7:00 am - 8:02 pmCHS Charleston-PTY Panama City Tocumen Intl

13h 02m1 stop Newark

8:55 am - 9:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 04m1 stop Houston George Bush Intcntl

$627United Airlines

Wed, Dec 2 - Mon, Dec 7

7:21 am - 2:34 pmCHS Charleston-PTY Panama City Tocumen Intl

7h 13m1 stop Miami

3:13 pm - 2:44 pmPTY Panama City Tocumen Intl-CHS Charleston

23h 31m2 stops Miami Dallas/Fort Worth

$631American Airlines

Fri, Nov 27 - Wed, Dec 2

5:00 pm - 5:12 pmCHS Charleston-PTY Panama City Tocumen Intl

24h 12m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:00 am - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 59m1 stop Newark

$631United Airlines

Wed, Dec 2 - Mon, Dec 7

7:21 am - 2:34 pmCHS Charleston-PTY Panama City Tocumen Intl

7h 13m1 stop Miami

3:13 pm - 10:50 amPTY Panama City Tocumen Intl-CHS Charleston

19h 37m2 stops Miami Washington, D.C. Reagan-National

$631American Airlines

Fri, Nov 27 - Wed, Dec 2

12:15 pm - 5:12 pmCHS Charleston-PTY Panama City Tocumen Intl

28h 57m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:00 am - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 59m1 stop Newark

$631United Airlines

Wed, Dec 2 - Mon, Dec 7

10:23 am - 8:02 pmCHS Charleston-PTY Panama City Tocumen Intl

9h 39m1 stop Newark

10:00 am - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 59m1 stop Newark

$676Copa Airlines

Wed, Dec 2 - Mon, Dec 7

7:00 am - 8:02 pmCHS Charleston-PTY Panama City Tocumen Intl

13h 02m1 stop Newark

8:55 am - 9:54 pmPTY Panama City Tocumen Intl-CHS Charleston

12h 59m1 stop Houston George Bush Intcntl

$677Copa Airlines

Thu, Dec 10 - Mon, Feb 1

7:40 am - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

18h 30m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

5:30 am - 10:22 pmPTY Panama City Tocumen Intl-CHS Charleston

16h 52m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$679Multiple Airlines

Fri, Dec 4 - Mon, Dec 7

6:00 am - 12:59 pmCHS Charleston-PTY Panama City Tocumen Intl

7h 59m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

8h 35m1 stop Atlanta Hartsfield-Jackson

$733Delta

Sat, Oct 24 - Wed, Oct 28

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American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets

American Airlines

Nov 27

CHS7:21 amCharleston

7h 13m

1 stop

PTY2:34 pmPanama City Tocumen Intl

Dec 2

PTY3:13 pmPanama City Tocumen Intl

7h 00m

1 stop

CHS10:13 pmCharleston

$627

American Airlines

Nov 27

CHS8:29 pmCharleston

18h 05m

2 stops

PTY2:34 pmPanama City Tocumen Intl

Dec 2

PTY3:13 pmPanama City Tocumen Intl

19h 54m

2 stops

CHS11:07 amCharleston

$665

American Airlines

Mar 20

CHS7:02 pmCharleston

20h 18m

2 stops

PTY2:20 pmPanama City Tocumen Intl

Mar 25

PTY3:13 pmPanama City Tocumen Intl

18h 13m

1 stop

CHS10:26 amCharleston

$676

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets

United Airlines

Dec 2

CHS5:00 pmCharleston

24h 12m

2 stops

PTY5:12 pmPanama City Tocumen Intl

Dec 7

PTY10:00 amPanama City Tocumen Intl

13h 59m

1 stop

CHS11:59 pmCharleston

$631

United Airlines

Dec 2

CHS5:00 pmCharleston

24h 12m

2 stops

PTY5:12 pmPanama City Tocumen Intl

Dec 7

PTY10:00 amPanama City Tocumen Intl

13h 59m

1 stop

CHS11:59 pmCharleston

$632

United Airlines

Nov 25

CHS3:35 pmCharleston

28h 27m

1 stop

PTY8:02 pmPanama City Tocumen Intl

Dec 2

PTY8:55 amPanama City Tocumen Intl

13h 04m

1 stop

CHS9:59 pmCharleston

$636

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Fri 11/27

7:21 am-2:34 pm

1 stop7h 13m

Panama City Tocumen Intl

Wed 12/2

3:13 pm-10:13 pm

1 stop7h 00m

$627

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Wed 12/2

7:00 am-8:02 pm

1 stop13h 02m

Panama City Tocumen Intl

Mon 12/7

8:55 am-9:59 pm

1 stop13h 04m

$627

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Fri 11/27

7:21 am-2:34 pm

1 stop7h 13m

Panama City Tocumen Intl

Wed 12/2

3:13 pm-2:44 pm

2 stops23h 31m

$631

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Wed 12/2

5:00 pm-5:12 pm

2 stops24h 12m

Panama City Tocumen Intl

Mon 12/7

10:00 am-11:59 pm

1 stop13h 59m

$631

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Fri 11/27

7:21 am-2:34 pm

1 stop7h 13m

Panama City Tocumen Intl

Wed 12/2

3:13 pm-10:50 am

2 stops19h 37m

$631

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Wed 12/2

12:15 pm-5:12 pm

2 stops28h 57m

Panama City Tocumen Intl

Mon 12/7

10:00 am-11:59 pm

1 stop13h 59m

$631

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Wed 12/2

10:23 am-8:02 pm

1 stop9h 39m

Panama City Tocumen Intl

Mon 12/7

10:00 am-11:59 pm

1 stop13h 59m

$676

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Thu 12/10

7:00 am-8:02 pm

1 stop13h 02m

Panama City Tocumen Intl

Mon 2/1

8:55 am-9:54 pm

1 stop12h 59m

$677

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Fri 12/4

7:40 am-2:10 am

2 stops18h 30m

Panama City Tocumen Intl

Mon 12/7

5:30 am-10:22 pm

2 stops16h 52m

$679

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Sat 10/24

6:00 am-12:59 pm

1 stop7h 59m

Panama City Tocumen Intl

Wed 10/28

2:24 pm-11:59 pm

1 stop8h 35m

$733

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Charleston and Panama City?

Prices are currently typical for flights on this route.

Typical prices usually range from $463 to $690.
The lowest price recently found on this route was $627.

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you’re not able to fly to Panama City in March, then October is your next best option. Flight prices from Charleston to Panama City during October average around $523.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Best Price Found	$277
Fastest flight time	8h 02m
Direct flights	None

The best one-way flight to Panama City from Charleston in the past 72 hours is $277. The best round-trip flight deal from Charleston to Panama City found on momondo in the last 72 hours is $627.

The fastest flight from Charleston to Panama City takes 8h 02m

There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.

Search flight deals

Frequently asked questions about flying from Charleston to Panama City

How far is Charleston to Panama City Tocumen Intl by plane?
The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 8h 02m is a normal flight duration for this route.
When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?
Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.
How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?
As of October 2026, there are 3 operators available to choose from for flights from Charleston Airport to Panama City Tocumen Intl Airport.
How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Charleston to Panama City?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Charleston to Panama City is American Airlines (52% of total bookings). The next most popular airlines are United Airlines (25%) and Delta (23%).

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $299	Free Cancellation	Rating 7.8 8,626 reviews	Search Delta flights
United Airlines	PriceFrom $369	Free Cancellation	Rating 7.4 10,283 reviews	Search United Airlines flights
American Airlines	PriceFrom $458	Free Cancellation	Rating 7.0 12,130 reviews	Search American Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

An easier way to manage your Panama City trip

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Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from Charleston to Panama City from $277

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 1/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets

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How to get the cheapest flight ticket from Charleston to Panama City

What is the typical price of a round-trip flight between Charleston and Panama City?

What is the cheapest month to fly to Panama City?

What is the cheapest airline that flies from Charleston to Panama City Tocumen Intl?

What airlines fly to Panama City?

Which airport is the most popular layover for flights between Charleston and Panama City?

Which layover airport offers the lowest fares from Charleston to Panama City?

Which layover airport has the shortest travel time from Charleston to Panama City?

Which layover airport has the shortest connection time from Charleston to Panama City?

When to book flights from Charleston to Panama City

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Charleston to Panama City

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Airports servicing Panama

Fly your favorite airline to Panama City

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama City

List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

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According to popular flight searches on momondo this year

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