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Cheap flights from Charleston to Panama City from $184

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 1/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charleston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:40 am - 4:12 pm
CHS
-
PTY
10h 32m1 stop
United Airlines Logo
10:00 am - 9:59 pm
PTY
-
CHS
10h 59m1 stop
$370United Airlines
Wed, Apr 8 - Tue, Apr 14
Delta Logo
5:20 am - 12:55 pm
CHS
-
PTY
8h 35m1 stop
Delta Logo
2:20 pm - 11:50 pm
PTY
-
CHS
8h 30m1 stop
$371Delta
Tue, Apr 14 - Tue, Apr 21
American Airlines Logo
7:42 pm - 1:27 pm
CHS
-
PTY
17h 45m2 stops
American Airlines Logo
2:27 pm - 2:25 pm
PTY
-
CHS
23h 58m2 stops
$374American Airlines
Tue, Jan 27 - Tue, Feb 3
American Airlines Logo
7:09 pm - 12:36 pm
CHS
-
PTY
18h 27m2 stops
American Airlines Logo
1:49 pm - 12:24 am
PTY
-
CHS
9h 35m1 stop
$375American Airlines
Tue, Apr 14 - Tue, Apr 21
United Airlines Logo
7:40 pm - 4:04 am
CHS
-
PTY
9h 24m1 stop
United Airlines Logo
3:30 pm - 9:59 pm
PTY
-
CHS
29h 29m1 stop
$378United Airlines
Tue, Apr 7 - Mon, Apr 13
United Airlines Logo
7:40 pm - 4:04 am
CHS
-
PTY
9h 24m1 stop
United Airlines Logo
7:55 am - 9:59 pm
PTY
-
CHS
13h 04m1 stop
$390United Airlines
Fri, Apr 10 - Mon, Apr 13
American Airlines Logo
7:02 pm - 12:40 pm
CHS
-
PTY
18h 38m2 stops
American Airlines Logo
1:40 pm - 11:59 pm
PTY
-
CHS
9h 19m1 stop
$394American Airlines
Sat, Mar 14 - Tue, Mar 17
American Airlines Logo
7:02 pm - 12:40 pm
CHS
-
PTY
18h 38m2 stops
American Airlines Logo
1:40 pm - 10:17 am
PTY
-
CHS
19h 37m2 stops
$395American Airlines
Sat, Mar 14 - Tue, Mar 17
American Airlines Logo
6:00 am - 3:52 pm
CHS
-
PTY
9h 52m1 stop
American Airlines Logo
2:27 pm - 8:47 am
PTY
-
CHS
18h 20m1 stop
$397American Airlines
Sat, Jan 31 - Thu, Feb 5
United Airlines Logo
6:35 am - 5:07 pm
CHS
-
PTY
10h 32m1 stop
United Airlines Logo
4:41 pm - 9:58 pm
PTY
-
CHS
29h 17m1 stop
$399United Airlines
Tue, Feb 17 - Fri, Feb 27

American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets
American Airlines
Jan 27
CHS7:42 pmCharleston
17h 45m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 3
PTY2:27 pmPanama City Tocumen Intl
23h 58m
2 stops
CHS2:25 pmCharleston
$374
Find similar
American Airlines
Apr 14
CHS7:09 pmCharleston
18h 27m
2 stops
PTY12:36 pmPanama City Tocumen Intl
Apr 21
PTY1:49 pmPanama City Tocumen Intl
9h 35m
1 stop
CHS12:24 amCharleston
$375
Find similar
American Airlines
Mar 14
CHS7:02 pmCharleston
18h 38m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Mar 17
PTY1:40 pmPanama City Tocumen Intl
9h 19m
1 stop
CHS11:59 pmCharleston
$394
Find similar

Copa Airlines flights from Charleston to Panama City

Our best Copa Airlines deals on Charleston to Panama City flight tickets
Copa Airlines
Mar 19
CHS6:30 amCharleston
13h 32m
1 stop
PTY7:02 pmPanama City Tocumen Intl
Mar 29
PTY10:55 pmPanama City Tocumen Intl
24h 04m
1 stop
CHS11:59 pmCharleston
$418
Find similar
Copa Airlines
Apr 5
CHS6:30 amCharleston
14h 01m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Apr 10
PTY3:30 pmPanama City Tocumen Intl
23h 41m
1 stop
CHS4:11 pmCharleston
$439
Find similar
Copa Airlines
Jan 5
CHS6:32 amCharleston
13h 30m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Jan 13
PTY4:41 pmPanama City Tocumen Intl
23h 36m
1 stop
CHS4:17 pmCharleston
$461
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 2, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/8

6:40 am-4:12 pm

1 stop10h 32m

Panama City Tocumen Intl

Tue 4/14

10:00 am-9:59 pm

1 stop10h 59m

$370

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 4/14

5:20 am-12:55 pm

1 stop8h 35m

Panama City Tocumen Intl

Tue 4/21

2:20 pm-11:50 pm

1 stop8h 30m

$371

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 1/27

7:42 pm-1:27 pm

2 stops17h 45m

Panama City Tocumen Intl

Tue 2/3

2:27 pm-2:25 pm

2 stops23h 58m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 4/14

7:09 pm-12:36 pm

2 stops18h 27m

Panama City Tocumen Intl

Tue 4/21

1:49 pm-12:24 am

1 stop9h 35m

$375

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 4/7

7:40 pm-4:04 am

1 stop9h 24m

Panama City Tocumen Intl

Mon 4/13

3:30 pm-9:59 pm

1 stop29h 29m

$378

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 4/10

7:40 pm-4:04 am

1 stop9h 24m

Panama City Tocumen Intl

Mon 4/13

7:55 am-9:59 pm

1 stop13h 04m

$390

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

7:02 pm-12:40 pm

2 stops18h 38m

Panama City Tocumen Intl

Tue 3/17

1:40 pm-11:59 pm

1 stop9h 19m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

7:02 pm-12:40 pm

2 stops18h 38m

Panama City Tocumen Intl

Tue 3/17

1:40 pm-10:17 am

2 stops19h 37m

$395

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 1/31

6:00 am-3:52 pm

1 stop9h 52m

Panama City Tocumen Intl

Thu 2/5

2:27 pm-8:47 am

1 stop18h 20m

$397

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 2/17

6:35 am-5:07 pm

1 stop10h 32m

Panama City Tocumen Intl

Fri 2/27

4:41 pm-9:58 pm

1 stop29h 17m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charleston and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $389. If you’re not able to fly to Panama City in September, then March is your next best option. Flight prices from Charleston to Panama City during March average around $413.

Can stopping save me money on Charleston to Panama City flights?

You could potentially save up to 9% on your flight if you consider stops on a Charleston to Panama City flight.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Fastest flight time

7h 37m

Direct flights

None
The fastest flight from Charleston to Panama City takes 7h 37m
There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.
Search flight deals

  • How far is Charleston to Panama City Tocumen Intl by plane?

    The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 7h 37m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Panama City?

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $349Free CancellationRating
7.9
8,021 reviews
Search Delta flights
American AirlinesPriceFrom $363Free CancellationRating
7.2
11,075 reviews
Search American Airlines flights
United AirlinesPriceFrom $369Free CancellationRating
7.4
9,132 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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