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Cheap flights from Charleston to Panama City from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 7/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charleston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:40 pm - 4:04 am
CHS
-
PTY
9h 24m
1 stop
United Airlines Logo
7:55 am - 9:59 pm
PTY
-
CHS
13h 04m
1 stop
$421United Airlines
Wed, Apr 15 - Wed, Apr 22
American Airlines Logo
6:09 pm - 12:40 pm
CHS
-
PTY
19h 31m
2 stops
American Airlines Logo
1:50 pm - 8:33 am
PTY
-
CHS
17h 43m
2 stops
$425American Airlines
Tue, Mar 31 - Fri, Apr 3
American Airlines Logo
6:20 pm - 12:46 pm
CHS
-
PTY
19h 26m
2 stops
American Airlines Logo
1:49 pm - 8:32 am
PTY
-
CHS
17h 43m
2 stops
$428American Airlines
Wed, Apr 15 - Wed, Apr 22
American Airlines Logo
8:08 pm - 12:40 pm
CHS
-
PTY
17h 32m
1 stop
American Airlines Logo
1:50 pm - 11:59 pm
PTY
-
CHS
9h 09m
1 stop
$429American Airlines
Mon, Mar 30 - Fri, Apr 3
United Airlines Logo
6:50 am - 6:37 pm
CHS
-
PTY
12h 47m
1 stop
United Airlines Logo
3:30 pm - 10:15 pm
PTY
-
CHS
29h 45m
1 stop
$430United Airlines
Thu, Jun 18 - Tue, Jun 23
Copa Airlines Logo
6:30 am - 7:02 pm
CHS
-
PTY
13h 32m
1 stop
Copa Airlines Logo
3:30 pm - 4:11 pm
PTY
-
CHS
23h 41m
1 stop
$432Copa Airlines
Mon, Mar 23 - Mon, Mar 30
American Airlines Logo
8:08 pm - 3:01 pm
CHS
-
PTY
19h 53m
1 stop
American Airlines Logo
1:50 pm - 8:33 am
PTY
-
CHS
17h 43m
2 stops
$434American Airlines
Mon, Mar 30 - Fri, Apr 3
United Airlines Logo
6:40 am - 6:37 pm
CHS
-
PTY
12h 57m
1 stop
United Airlines Logo
7:55 am - 9:59 pm
PTY
-
CHS
13h 04m
1 stop
$438United Airlines
Wed, Apr 8 - Wed, Apr 15
United Airlines Logo
6:50 am - 4:12 pm
CHS
-
PTY
10h 22m
1 stop
United Airlines Logo
10:55 pm - 8:54 am
PTY
-
CHS
8h 59m
1 stop
$441United Airlines
Mon, Jun 22 - Sun, Jul 5
American Airlines Logo
4:46 pm - 12:46 pm
CHS
-
PTY
21h 00m
2 stops
American Airlines Logo
1:49 pm - 11:39 am
PTY
-
CHS
20h 50m
2 stops
$445American Airlines
Fri, Apr 10 - Fri, Apr 17

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets
United Airlines
Apr 15
CHS7:40 pmCharleston
9h 24m
1 stop
PTY4:04 amPanama City Tocumen Intl
Apr 22
PTY7:55 amPanama City Tocumen Intl
13h 04m
1 stop
CHS9:59 pmCharleston
$421
United Airlines
Jun 18
CHS6:50 amCharleston
12h 47m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jun 23
PTY3:30 pmPanama City Tocumen Intl
29h 45m
1 stop
CHS10:15 pmCharleston
$430
United Airlines
Apr 8
CHS6:40 amCharleston
12h 57m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 15
PTY7:55 amPanama City Tocumen Intl
13h 04m
1 stop
CHS9:59 pmCharleston
$438

Copa Airlines flights from Charleston to Panama City

Our best Copa Airlines deals on Charleston to Panama City flight tickets
Copa Airlines
Mar 23
CHS6:30 amCharleston
13h 32m
1 stop
PTY7:02 pmPanama City Tocumen Intl
Mar 30
PTY3:30 pmPanama City Tocumen Intl
23h 41m
1 stop
CHS4:11 pmCharleston
$432
Copa Airlines
Apr 1
CHS6:40 amCharleston
12h 57m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 8
PTY9:45 amPanama City Tocumen Intl
13h 14m
1 stop
CHS11:59 pmCharleston
$485
Copa Airlines
Feb 28
CHS5:05 pmCharleston
24h 02m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Mar 5
PTY10:00 amPanama City Tocumen Intl
13h 30m
1 stop
CHS11:30 pmCharleston
$547

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/15

7:40 pm-4:04 am

1 stop9h 24m

Panama City Tocumen Intl

Wed 4/22

7:55 am-9:59 pm

1 stop13h 04m

$421

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/31

6:09 pm-12:40 pm

2 stops19h 31m

Panama City Tocumen Intl

Fri 4/3

1:50 pm-8:33 am

2 stops17h 43m

$425

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/15

6:20 pm-12:46 pm

2 stops19h 26m

Panama City Tocumen Intl

Wed 4/22

1:49 pm-8:32 am

2 stops17h 43m

$428

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 3/30

8:08 pm-12:40 pm

1 stop17h 32m

Panama City Tocumen Intl

Fri 4/3

1:50 pm-11:59 pm

1 stop9h 09m

$429

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 6/18

6:50 am-6:37 pm

1 stop12h 47m

Panama City Tocumen Intl

Tue 6/23

3:30 pm-10:15 pm

1 stop29h 45m

$430

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 3/23

6:30 am-7:02 pm

1 stop13h 32m

Panama City Tocumen Intl

Mon 3/30

3:30 pm-4:11 pm

1 stop23h 41m

$432

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 3/30

8:08 pm-3:01 pm

1 stop19h 53m

Panama City Tocumen Intl

Fri 4/3

1:50 pm-8:33 am

2 stops17h 43m

$434

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 4/8

6:40 am-6:37 pm

1 stop12h 57m

Panama City Tocumen Intl

Wed 4/15

7:55 am-9:59 pm

1 stop13h 04m

$438

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 6/22

6:50 am-4:12 pm

1 stop10h 22m

Panama City Tocumen Intl

Sun 7/5

10:55 pm-8:54 am

1 stop8h 59m

$441

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 4/10

4:46 pm-12:46 pm

2 stops21h 00m

Panama City Tocumen Intl

Fri 4/17

1:49 pm-11:39 am

2 stops20h 50m

$445

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $389. If you’re not able to fly to Panama City in September, then August is your next best option. Flight prices from Charleston to Panama City during August average around $456.

Can stopping save me money on Charleston to Panama City flights?

You could potentially save up to 2% on your flight if you consider stops on a Charleston to Panama City flight.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Fastest flight time

8h 47m

Direct flights

None
The fastest flight from Charleston to Panama City takes 8h 47m
There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.
Search flight deals

  • How far is Charleston to Panama City Tocumen Intl by plane?

    The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 8h 47m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Panama City?

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $309Free CancellationRating
7.9
8,236 reviews
Search Delta flights
American AirlinesPriceFrom $363Free CancellationRating
7.2
11,339 reviews
Search American Airlines flights
United AirlinesPriceFrom $369Free CancellationRating
7.4
9,342 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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