Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Charleston to Panama City from $215

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 2/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Charleston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:15 am - 8:02 pm
CHS
-
PTY
8h 47m
1 stop
United Airlines Logo
4:41 pm - 4:13 pm
PTY
-
CHS
23h 32m
1 stop
$399United Airlines
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
6:45 pm - 2:20 pm
CHS
-
PTY
20h 35m
2 stops
American Airlines Logo
1:40 pm - 11:16 am
PTY
-
CHS
20h 36m
2 stops
$415American Airlines
Sat, Mar 14 - Tue, Mar 17
American Airlines Logo
8:08 pm - 2:20 pm
CHS
-
PTY
19h 12m
1 stop
American Airlines Logo
1:40 pm - 11:59 pm
PTY
-
CHS
9h 19m
1 stop
$419American Airlines
Sat, Mar 14 - Tue, Mar 17
United Airlines Logo
11:03 am - 7:31 pm
CHS
-
PTY
9h 28m
1 stop
United Airlines Logo
10:55 pm - 8:54 am
PTY
-
CHS
8h 59m
1 stop
$424United Airlines
Tue, Jun 2 - Sun, Jun 7
Delta Logo
5:20 am - 1:02 pm
CHS
-
PTY
8h 42m
1 stop
Delta Logo
2:27 pm - 11:50 pm
PTY
-
CHS
8h 23m
1 stop
$431Delta
Sun, Apr 26 - Sat, May 2
American Airlines Logo
6:00 am - 12:36 pm
CHS
-
PTY
7h 36m
1 stop
American Airlines Logo
1:49 pm - 11:38 am
PTY
-
CHS
20h 49m
2 stops
$435American Airlines
Sun, Apr 26 - Sat, May 2
American Airlines Logo
8:21 pm - 12:36 pm
CHS
-
PTY
17h 15m
2 stops
American Airlines Logo
1:49 pm - 11:39 am
PTY
-
CHS
20h 50m
2 stops
$448American Airlines
Mon, Apr 20 - Fri, Apr 24
American Airlines Logo
8:09 pm - 12:36 pm
CHS
-
PTY
17h 27m
1 stop
American Airlines Logo
1:49 pm - 11:39 am
PTY
-
CHS
20h 50m
2 stops
$456American Airlines
Mon, Apr 20 - Fri, Apr 24
American Airlines Logo
8:25 pm - 3:15 pm
CHS
-
PTY
18h 50m
2 stops
American Airlines Logo
4:05 pm - 10:26 am
PTY
-
CHS
18h 21m
1 stop
$483American Airlines
Thu, Feb 26 - Sun, Mar 1
American Airlines Logo
8:21 pm - 12:36 pm
CHS
-
PTY
17h 15m
2 stops
American Airlines Logo
1:49 pm - 11:44 am
PTY
-
CHS
20h 55m
2 stops
$488American Airlines
Sun, Apr 26 - Sat, May 2

American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets
American Airlines
Mar 14
CHS6:45 pmCharleston
20h 35m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 17
PTY1:40 pmPanama City Tocumen Intl
20h 36m
2 stops
CHS11:16 amCharleston
$415
American Airlines
Mar 14
CHS8:08 pmCharleston
19h 12m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Mar 17
PTY1:40 pmPanama City Tocumen Intl
9h 19m
1 stop
CHS11:59 pmCharleston
$419
American Airlines
Apr 26
CHS6:00 amCharleston
7h 36m
1 stop
PTY12:36 pmPanama City Tocumen Intl
May 2
PTY1:49 pmPanama City Tocumen Intl
20h 49m
2 stops
CHS11:38 amCharleston
$435

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets
United Airlines
Feb 26
CHS11:15 amCharleston
8h 47m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Mar 2
PTY4:41 pmPanama City Tocumen Intl
23h 32m
1 stop
CHS4:13 pmCharleston
$399
United Airlines
Jun 2
CHS11:03 amCharleston
9h 28m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Jun 7
PTY10:55 pmPanama City Tocumen Intl
8h 59m
1 stop
CHS8:54 amCharleston
$424
United Airlines
Apr 20
CHS7:40 pmCharleston
9h 24m
1 stop
PTY4:04 amPanama City Tocumen Intl
Apr 24
PTY3:30 pmPanama City Tocumen Intl
29h 29m
1 stop
CHS9:59 pmCharleston
$493

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 2/26

11:15 am-8:02 pm

1 stop8h 47m

Panama City Tocumen Intl

Mon 3/2

4:41 pm-4:13 pm

1 stop23h 32m

$399

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

6:45 pm-2:20 pm

2 stops20h 35m

Panama City Tocumen Intl

Tue 3/17

1:40 pm-11:16 am

2 stops20h 36m

$415

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

8:08 pm-2:20 pm

1 stop19h 12m

Panama City Tocumen Intl

Tue 3/17

1:40 pm-11:59 pm

1 stop9h 19m

$419

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 6/2

11:03 am-7:31 pm

1 stop9h 28m

Panama City Tocumen Intl

Sun 6/7

10:55 pm-8:54 am

1 stop8h 59m

$424

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 4/26

5:20 am-1:02 pm

1 stop8h 42m

Panama City Tocumen Intl

Sat 5/2

2:27 pm-11:50 pm

1 stop8h 23m

$431

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 4/26

6:00 am-12:36 pm

1 stop7h 36m

Panama City Tocumen Intl

Sat 5/2

1:49 pm-11:38 am

2 stops20h 49m

$435

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 4/20

8:21 pm-12:36 pm

2 stops17h 15m

Panama City Tocumen Intl

Fri 4/24

1:49 pm-11:39 am

2 stops20h 50m

$448

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 4/20

8:09 pm-12:36 pm

1 stop17h 27m

Panama City Tocumen Intl

Fri 4/24

1:49 pm-11:39 am

2 stops20h 50m

$456

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 2/26

8:25 pm-3:15 pm

2 stops18h 50m

Panama City Tocumen Intl

Sun 3/1

4:05 pm-10:26 am

1 stop18h 21m

$483

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 4/26

8:21 pm-12:36 pm

2 stops17h 15m

Panama City Tocumen Intl

Sat 5/2

1:49 pm-11:44 am

2 stops20h 55m

$488

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charleston and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $389. If you’re not able to fly to Panama City in September, then March is your next best option. Flight prices from Charleston to Panama City during March average around $413.

Can stopping save me money on Charleston to Panama City flights?

You could potentially save up to 9% on your flight if you consider stops on a Charleston to Panama City flight.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Fastest flight time

8h 14m

Direct flights

None
The fastest flight from Charleston to Panama City takes 8h 14m
There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.
Search flight deals

  • How far is Charleston to Panama City Tocumen Intl by plane?

    The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 8h 14m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Panama City?

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $309Free CancellationRating
7.9
8,128 reviews
Search Delta flights
American AirlinesPriceFrom $363Free CancellationRating
7.2
11,205 reviews
Search American Airlines flights
United AirlinesPriceFrom $369Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 2/28
Sat 3/7
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama