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Cheap flights from Charleston to Panama City from $391

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charleston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 1:40 pm
CHS
-
PTY
7h 40m
1 stop
American Airlines Logo
1:40 pm - 11:59 pm
PTY
-
CHS
9h 19m
1 stop
$391American Airlines
Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
7:43 pm - 1:40 pm
CHS
-
PTY
17h 57m
2 stops
American Airlines Logo
1:40 pm - 8:33 am
PTY
-
CHS
17h 53m
2 stops
$395American Airlines
Tue, Mar 3 - Tue, Mar 10
United Airlines Logo
11:15 am - 8:02 pm
CHS
-
PTY
8h 47m
1 stop
United Airlines Logo
4:41 pm - 9:58 pm
PTY
-
CHS
29h 17m
1 stop
$399United Airlines
Thu, Feb 26 - Mon, Mar 2
American Airlines Logo
11:06 am - 3:01 pm
CHS
-
PTY
28h 55m
1 stop
American Airlines Logo
1:50 pm - 8:33 am
PTY
-
CHS
17h 43m
2 stops
$403American Airlines
Mon, Mar 30 - Fri, Apr 3
American Airlines Logo
8:09 pm - 12:36 pm
CHS
-
PTY
17h 27m
1 stop
American Airlines Logo
1:49 pm - 10:24 am
PTY
-
CHS
19h 35m
1 stop
$407American Airlines
Mon, Apr 20 - Thu, Apr 23
American Airlines Logo
7:13 pm - 12:36 pm
CHS
-
PTY
18h 23m
2 stops
American Airlines Logo
1:49 pm - 4:06 pm
PTY
-
CHS
25h 17m
2 stops
$410American Airlines
Mon, Apr 20 - Thu, Apr 23
Delta Logo
6:30 am - 12:55 pm
CHS
-
PTY
7h 25m
1 stop
Delta Logo
2:20 pm - 11:50 pm
PTY
-
CHS
8h 30m
1 stop
$411Delta
Fri, May 1 - Tue, May 5
American Airlines Logo
7:03 pm - 3:15 pm
CHS
-
PTY
20h 12m
2 stops
American Airlines Logo
3:10 pm - 11:59 pm
PTY
-
CHS
7h 49m
1 stop
$415American Airlines
Sat, Feb 28 - Tue, Mar 10
American Airlines Logo
8:25 pm - 3:15 pm
CHS
-
PTY
18h 50m
2 stops
American Airlines Logo
2:40 pm - 12:42 pm
PTY
-
CHS
22h 02m
2 stops
$420American Airlines
Thu, Feb 26 - Sun, Mar 1
American Airlines Logo
8:09 pm - 12:36 pm
CHS
-
PTY
17h 27m
1 stop
American Airlines Logo
1:49 pm - 11:12 am
PTY
-
CHS
20h 23m
2 stops
$423American Airlines
Thu, Apr 16 - Mon, Apr 20

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets
United Airlines
Feb 26
CHS11:15 amCharleston
8h 47m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Mar 2
PTY4:41 pmPanama City Tocumen Intl
29h 17m
1 stop
CHS9:58 pmCharleston
$399
United Airlines
Mar 14
CHS7:01 pmCharleston
10h 09m
1 stop
PTY4:10 amPanama City Tocumen Intl
Mar 17
PTY3:41 pmPanama City Tocumen Intl
23h 27m
1 stop
CHS4:08 pmCharleston
$436
United Airlines
Feb 28
CHS5:05 pmCharleston
24h 02m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Mar 10
PTY3:41 pmPanama City Tocumen Intl
29h 17m
1 stop
CHS9:58 pmCharleston
$461

American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets
American Airlines
Mar 3
CHS6:00 amCharleston
7h 40m
1 stop
PTY1:40 pmPanama City Tocumen Intl
Mar 10
PTY1:40 pmPanama City Tocumen Intl
9h 19m
1 stop
CHS11:59 pmCharleston
$391
American Airlines
Mar 3
CHS7:43 pmCharleston
17h 57m
2 stops
PTY1:40 pmPanama City Tocumen Intl
Mar 10
PTY1:40 pmPanama City Tocumen Intl
17h 53m
2 stops
CHS8:33 amCharleston
$395
American Airlines
Mar 30
CHS11:06 amCharleston
28h 55m
1 stop
PTY3:01 pmPanama City Tocumen Intl
Apr 3
PTY1:50 pmPanama City Tocumen Intl
17h 43m
2 stops
CHS8:33 amCharleston
$403

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 18, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/3

6:00 am-1:40 pm

1 stop7h 40m

Panama City Tocumen Intl

Tue 3/10

1:40 pm-11:59 pm

1 stop9h 19m

$391

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/3

7:43 pm-1:40 pm

2 stops17h 57m

Panama City Tocumen Intl

Tue 3/10

1:40 pm-8:33 am

2 stops17h 53m

$395

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 2/26

11:15 am-8:02 pm

1 stop8h 47m

Panama City Tocumen Intl

Mon 3/2

4:41 pm-9:58 pm

1 stop29h 17m

$399

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 3/30

11:06 am-3:01 pm

1 stop28h 55m

Panama City Tocumen Intl

Fri 4/3

1:50 pm-8:33 am

2 stops17h 43m

$403

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 4/20

8:09 pm-12:36 pm

1 stop17h 27m

Panama City Tocumen Intl

Thu 4/23

1:49 pm-10:24 am

1 stop19h 35m

$407

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 4/20

7:13 pm-12:36 pm

2 stops18h 23m

Panama City Tocumen Intl

Thu 4/23

1:49 pm-4:06 pm

2 stops25h 17m

$410

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 5/1

6:30 am-12:55 pm

1 stop7h 25m

Panama City Tocumen Intl

Tue 5/5

2:20 pm-11:50 pm

1 stop8h 30m

$411

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 2/28

7:03 pm-3:15 pm

2 stops20h 12m

Panama City Tocumen Intl

Tue 3/10

3:10 pm-11:59 pm

1 stop7h 49m

$415

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 2/26

8:25 pm-3:15 pm

2 stops18h 50m

Panama City Tocumen Intl

Sun 3/1

2:40 pm-12:42 pm

2 stops22h 02m

$420

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 4/16

8:09 pm-12:36 pm

1 stop17h 27m

Panama City Tocumen Intl

Mon 4/20

1:49 pm-11:12 am

2 stops20h 23m

$423

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charleston and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $389. If you’re not able to fly to Panama City in September, then March is your next best option. Flight prices from Charleston to Panama City during March average around $413.

Can stopping save me money on Charleston to Panama City flights?

You could potentially save up to 9% on your flight if you consider stops on a Charleston to Panama City flight.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Fastest flight time

8h 47m

Direct flights

None
The fastest flight from Charleston to Panama City takes 8h 47m
There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.
Search flight deals

  • How far is Charleston to Panama City Tocumen Intl by plane?

    The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 8h 47m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Panama City?

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $349Free CancellationRating
7.9
8,075 reviews
Search Delta flights
American AirlinesPriceFrom $363Free CancellationRating
7.2
11,160 reviews
Search American Airlines flights
United AirlinesPriceFrom $369Free CancellationRating
7.4
9,177 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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