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Cheap flights from Charleston to Panama City from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Charleston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 3:01 pm
CHS
-
PTY
10h 01m
1 stop
American Airlines Logo
3:51 pm - 11:59 pm
PTY
-
CHS
7h 08m
1 stop
$421American Airlines
Tue, Mar 31 - Fri, Apr 3
American Airlines Logo
7:43 pm - 3:01 pm
CHS
-
PTY
20h 18m
2 stops
American Airlines Logo
1:50 pm - 11:59 pm
PTY
-
CHS
9h 09m
1 stop
$425American Airlines
Tue, Mar 31 - Fri, Apr 3
United Airlines Logo
7:40 pm - 4:04 am
CHS
-
PTY
9h 24m
1 stop
United Airlines Logo
7:55 am - 9:59 pm
PTY
-
CHS
13h 04m
1 stop
$427United Airlines
Mon, Apr 13 - Mon, Apr 20
American Airlines Logo
8:08 pm - 3:01 pm
CHS
-
PTY
19h 53m
1 stop
American Airlines Logo
1:50 pm - 11:59 pm
PTY
-
CHS
9h 09m
1 stop
$429American Airlines
Mon, Mar 30 - Fri, Apr 3
American Airlines Logo
7:19 pm - 12:40 pm
CHS
-
PTY
18h 21m
2 stops
American Airlines Logo
1:50 pm - 2:14 pm
PTY
-
CHS
23h 24m
2 stops
$440American Airlines
Mon, Mar 30 - Fri, Apr 3
American Airlines Logo
8:21 pm - 12:46 pm
CHS
-
PTY
17h 25m
2 stops
American Airlines Logo
1:49 pm - 11:12 am
PTY
-
CHS
20h 23m
2 stops
$445American Airlines
Mon, Apr 13 - Mon, Apr 20
American Airlines Logo
8:09 pm - 12:46 pm
CHS
-
PTY
17h 37m
1 stop
American Airlines Logo
1:49 pm - 11:49 am
PTY
-
CHS
21h 00m
2 stops
$449American Airlines
Mon, Apr 20 - Fri, Apr 24
United Airlines Logo
5:15 pm - 2:14 pm
CHS
-
PTY
21h 59m
1 stop
United Airlines Logo
10:55 pm - 9:00 am
PTY
-
CHS
9h 05m
1 stop
$450United Airlines
Mon, Apr 20 - Fri, Apr 24
American Airlines Logo
6:00 am - 2:20 pm
CHS
-
PTY
9h 20m
1 stop
American Airlines Logo
3:10 pm - 11:59 pm
PTY
-
CHS
7h 49m
1 stop
$453American Airlines
Tue, Mar 17 - Thu, Mar 26
American Airlines Logo
6:10 am - 2:20 pm
CHS
-
PTY
9h 10m
2 stops
American Airlines Logo
1:40 pm - 11:59 pm
PTY
-
CHS
9h 19m
1 stop
$457American Airlines
Tue, Mar 17 - Thu, Mar 26

American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets
American Airlines
Mar 31
CHS7:43 pmCharleston
20h 18m
2 stops
PTY3:01 pmPanama City Tocumen Intl
Apr 3
PTY1:50 pmPanama City Tocumen Intl
9h 09m
1 stop
CHS11:59 pmCharleston
$425
American Airlines
Mar 30
CHS8:08 pmCharleston
19h 53m
1 stop
PTY3:01 pmPanama City Tocumen Intl
Apr 3
PTY1:50 pmPanama City Tocumen Intl
9h 09m
1 stop
CHS11:59 pmCharleston
$429
American Airlines
Mar 30
CHS7:19 pmCharleston
18h 21m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Apr 3
PTY1:50 pmPanama City Tocumen Intl
23h 24m
2 stops
CHS2:14 pmCharleston
$440

Copa Airlines flights from Charleston to Panama City

Our best Copa Airlines deals on Charleston to Panama City flight tickets
Copa Airlines
Mar 12
CHS6:30 amCharleston
13h 32m
1 stop
PTY7:02 pmPanama City Tocumen Intl
Apr 7
PTY3:30 pmPanama City Tocumen Intl
23h 41m
1 stop
CHS4:11 pmCharleston
$511
Copa Airlines
Apr 29
CHS7:40 pmCharleston
9h 24m
1 stop
PTY4:04 amPanama City Tocumen Intl
May 4
PTY10:00 amPanama City Tocumen Intl
10h 59m
1 stop
CHS9:59 pmCharleston
$679

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/31

6:00 am-3:01 pm

1 stop10h 01m

Panama City Tocumen Intl

Fri 4/3

3:51 pm-11:59 pm

1 stop7h 08m

$421

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/31

7:43 pm-3:01 pm

2 stops20h 18m

Panama City Tocumen Intl

Fri 4/3

1:50 pm-11:59 pm

1 stop9h 09m

$425

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 4/13

7:40 pm-4:04 am

1 stop9h 24m

Panama City Tocumen Intl

Mon 4/20

7:55 am-9:59 pm

1 stop13h 04m

$427

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 3/30

8:08 pm-3:01 pm

1 stop19h 53m

Panama City Tocumen Intl

Fri 4/3

1:50 pm-11:59 pm

1 stop9h 09m

$429

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 3/30

7:19 pm-12:40 pm

2 stops18h 21m

Panama City Tocumen Intl

Fri 4/3

1:50 pm-2:14 pm

2 stops23h 24m

$440

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 4/13

8:21 pm-12:46 pm

2 stops17h 25m

Panama City Tocumen Intl

Mon 4/20

1:49 pm-11:12 am

2 stops20h 23m

$445

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 4/20

8:09 pm-12:46 pm

1 stop17h 37m

Panama City Tocumen Intl

Fri 4/24

1:49 pm-11:49 am

2 stops21h 00m

$449

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 4/20

5:15 pm-2:14 pm

1 stop21h 59m

Panama City Tocumen Intl

Fri 4/24

10:55 pm-9:00 am

1 stop9h 05m

$450

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/17

6:00 am-2:20 pm

1 stop9h 20m

Panama City Tocumen Intl

Thu 3/26

3:10 pm-11:59 pm

1 stop7h 49m

$453

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/17

6:10 am-2:20 pm

2 stops9h 10m

Panama City Tocumen Intl

Thu 3/26

1:40 pm-11:59 pm

1 stop9h 19m

$457

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $389. If you’re not able to fly to Panama City in September, then August is your next best option. Flight prices from Charleston to Panama City during August average around $456.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Fastest flight time

8h 10m

Direct flights

None
The fastest flight from Charleston to Panama City takes 8h 10m
There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.
Search flight deals

  • How far is Charleston to Panama City Tocumen Intl by plane?

    The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 8h 10m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Panama City?

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $309Free CancellationRating
7.9
8,237 reviews
Search Delta flights
American AirlinesPriceFrom $363Free CancellationRating
7.1
11,369 reviews
Search American Airlines flights
United AirlinesPriceFrom $369Free CancellationRating
7.4
9,375 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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