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Cheap flights from Charleston to Panama City from $370

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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United Airlines Logo
6:35 am - 7:38 pmCHS-PTY
13h 03m1 stop
United Airlines Logo
11:35 am - 9:58 pmPTY-CHS
9h 23m1 stop
$370United Airlines
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Tue, Mar 3 - Tue, Mar 10
American Airlines Logo
5:06 pm - 1:50 pmCHS-PTY
20h 44m2 stops
American Airlines Logo
3:13 pm - 11:59 pmPTY-CHS
7h 46m1 stop
$374American Airlines
Find Deal
Tue, Mar 3 - Tue, Mar 10
United Airlines Logo
11:00 am - 8:02 pmCHS-PTY
9h 02m1 stop
United Airlines Logo
4:41 pm - 3:59 pmPTY-CHS
23h 18m1 stop
$378United Airlines
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Mon, Jan 26 - Thu, Jan 29
American Airlines Logo
8:07 pm - 1:27 pmCHS-PTY
17h 20m1 stop
American Airlines Logo
4:50 pm - 11:41 amPTY-CHS
18h 51m2 stops
$382American Airlines
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Mon, Jan 5 - Fri, Jan 16
United Airlines Logo
5:07 pm - 2:45 pmCHS-PTY
21h 38m1 stop
United Airlines Logo
3:41 pm - 9:58 pmPTY-CHS
29h 17m1 stop
$386United Airlines
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Mon, Feb 23 - Mon, Mar 9
American Airlines Logo
4:29 pm - 12:40 pmCHS-PTY
21h 11m2 stops
American Airlines Logo
1:44 pm - 10:17 amPTY-CHS
19h 33m2 stops
$394American Airlines
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Sat, Mar 14 - Tue, Mar 17
American Airlines Logo
7:20 pm - 1:50 pmCHS-PTY
18h 30m2 stops
American Airlines Logo
3:13 pm - 10:26 amPTY-CHS
18h 13m1 stop
$402American Airlines
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Mon, Feb 23 - Mon, Mar 9
United Airlines Logo
7:38 pm - 5:10 amCHS-PTY
9h 32m1 stop
United Airlines Logo
10:55 pm - 9:15 amPTY-CHS
9h 20m1 stop
$410United Airlines
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Fri, Mar 6 - Sun, Mar 8
American Airlines Logo
5:41 pm - 1:27 pmCHS-PTY
19h 46m2 stops
American Airlines Logo
2:27 pm - 9:48 amPTY-CHS
19h 21m2 stops
$419American Airlines
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Fri, Jan 16 - Sun, Feb 1
American Airlines Logo
8:07 pm - 1:27 pmCHS-PTY
17h 20m1 stop
American Airlines Logo
4:50 pm - 11:58 pmPTY-CHS
7h 08m1 stop
$430American Airlines
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Mon, Jan 5 - Fri, Jan 16

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets
United Airlines
Mar 3
CHS6:35 amCharleston
13h 03m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Mar 10
PTY11:35 amPanama City Tocumen Intl
9h 23m
1 stop
CHS9:58 pmCharleston
$370
Find similar
United Airlines
Jan 26
CHS11:00 amCharleston
9h 02m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Jan 29
PTY4:41 pmPanama City Tocumen Intl
23h 18m
1 stop
CHS3:59 pmCharleston
$378
Find similar
United Airlines
Feb 23
CHS5:07 pmCharleston
21h 38m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Mar 9
PTY3:41 pmPanama City Tocumen Intl
29h 17m
1 stop
CHS9:58 pmCharleston
$386
Find similar

American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets
American Airlines
Mar 3
CHS5:06 pmCharleston
20h 44m
2 stops
PTY1:50 pmPanama City Tocumen Intl
Mar 10
PTY3:13 pmPanama City Tocumen Intl
7h 46m
1 stop
CHS11:59 pmCharleston
$374
Find similar
American Airlines
Jan 5
CHS8:07 pmCharleston
17h 20m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Jan 16
PTY4:50 pmPanama City Tocumen Intl
18h 51m
2 stops
CHS11:41 amCharleston
$382
Find similar
American Airlines
Mar 14
CHS4:29 pmCharleston
21h 11m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Mar 17
PTY1:44 pmPanama City Tocumen Intl
19h 33m
2 stops
CHS10:17 amCharleston
$394
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/3

6:35 am-7:38 pm

1 stop13h 03m

Panama City Tocumen Intl

Tue 3/10

11:35 am-9:58 pm

1 stop9h 23m

$370

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 3/3

5:06 pm-1:50 pm

2 stops20h 44m

Panama City Tocumen Intl

Tue 3/10

3:13 pm-11:59 pm

1 stop7h 46m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 1/26

11:00 am-8:02 pm

1 stop9h 02m

Panama City Tocumen Intl

Thu 1/29

4:41 pm-3:59 pm

1 stop23h 18m

$378

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 1/5

8:07 pm-1:27 pm

1 stop17h 20m

Panama City Tocumen Intl

Fri 1/16

4:50 pm-11:41 am

2 stops18h 51m

$382

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 2/23

5:07 pm-2:45 pm

1 stop21h 38m

Panama City Tocumen Intl

Mon 3/9

3:41 pm-9:58 pm

1 stop29h 17m

$386

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 3/14

4:29 pm-12:40 pm

2 stops21h 11m

Panama City Tocumen Intl

Tue 3/17

1:44 pm-10:17 am

2 stops19h 33m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 2/23

7:20 pm-1:50 pm

2 stops18h 30m

Panama City Tocumen Intl

Mon 3/9

3:13 pm-10:26 am

1 stop18h 13m

$402

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 3/6

7:38 pm-5:10 am

1 stop9h 32m

Panama City Tocumen Intl

Sun 3/8

10:55 pm-9:15 am

1 stop9h 20m

$410

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 1/16

5:41 pm-1:27 pm

2 stops19h 46m

Panama City Tocumen Intl

Sun 2/1

2:27 pm-9:48 am

2 stops19h 21m

$419

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 1/5

8:07 pm-1:27 pm

1 stop17h 20m

Panama City Tocumen Intl

Fri 1/16

4:50 pm-11:58 pm

1 stop7h 08m

$430

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $389. If you’re not able to fly to Panama City in September, then November is your next best option. Flight prices from Charleston to Panama City during November average around $402.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $341. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $712. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Charleston to Panama City during this time can be as low as $466. Try not to purchase tickets in the afternoon because they tend to be around $495. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Charleston to Panama City flights?

You could potentially save up to 56% on your flight if you consider stops on a Charleston to Panama City flight.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Fastest flight time

8h 44m

Direct flights

None
The fastest flight from Charleston to Panama City takes 8h 44m
There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.
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  • How far is Charleston to Panama City Tocumen Intl by plane?

    The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 6h 27m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Panama City?

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $349Free CancellationRating
7.9
8,011 reviews
Search Delta flights
American AirlinesPriceFrom $373Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
United AirlinesPriceFrom $382Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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