What airlines fly to Panama City?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama City from Charleston according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Charleston to Panama City?

Miami (MIA) has the shortest average layover time for this route: 3h 15m.

Which layover airport offers the lowest fares from Charleston to Panama City?

Flights via Houston (IAH) offer the lowest average round-trip price of $682.

What is the cheapest airline that flies from Charleston to Panama City Tocumen Intl?

American Airlines and Copa Airlines are the most popular carriers operating from Charleston to Panama City Tocumen Intl

Which layover airport has the shortest travel time from Charleston to Panama City?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 8h 00m.

Which airport is the most popular layover for flights between Charleston and Panama City?

Miami (MIA) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

As of September 2026, there are 3 operators available to choose from for flights from Charleston Airport to Panama City Tocumen Intl Airport.

How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$276 Cheap Flights from Charleston to Panama City in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to Panama City

Round-trip

One-way

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Cheap round-trip flights

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10:10 am - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

16h 00m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

3:55 pm - 9:20 amPTY Panama City Tocumen Intl-CHS Charleston

17h 25m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$582Multiple Airlines

Thu, Jan 14 - Tue, Jan 19

7:40 am - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

18h 30m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

3:55 pm - 11:52 amPTY Panama City Tocumen Intl-CHS Charleston

19h 57m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$582Multiple Airlines

Fri, Dec 4 - Sat, Dec 12

7:40 am - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

18h 30m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

3:55 pm - 11:52 amPTY Panama City Tocumen Intl-CHS Charleston

19h 57m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

$582Multiple Airlines

Sat, Dec 5 - Sat, Dec 12

6:00 am - 1:59 pmCHS Charleston-PTY Panama City Tocumen Intl

7h 59m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

8h 30m1 stop Atlanta Hartsfield-Jackson

$597Delta

Thu, Nov 5 - Mon, Nov 9

6:30 am - 6:38 pmCHS Charleston-PTY Panama City Tocumen Intl

13h 08m1 stop Houston George Bush Intcntl

10:00 am - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 59m1 stop Newark

$597United Airlines

Thu, Oct 29 - Tue, Nov 3

7:04 pm - 1:02 pmCHS Charleston-PTY Panama City Tocumen Intl

18h 58m2 stops Charlotte Douglas Miami

3:13 pm - 11:24 amPTY Panama City Tocumen Intl-CHS Charleston

20h 11m2 stops Miami Chicago O'Hare Intl

$601American Airlines

Thu, Oct 29 - Tue, Nov 3

6:30 am - 6:38 pmCHS Charleston-PTY Panama City Tocumen Intl

13h 08m1 stop Houston George Bush Intcntl

4:41 pm - 1:56 pmPTY Panama City Tocumen Intl-CHS Charleston

21h 15m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$601United Airlines

Thu, Oct 29 - Tue, Nov 3

7:15 am - 3:55 pmCHS Charleston-PTY Panama City Tocumen Intl

8h 40m1 stop Miami

4:55 pm - 11:58 pmPTY Panama City Tocumen Intl-CHS Charleston

7h 03m1 stop Miami

$602American Airlines

Wed, Jan 20 - Thu, Jan 28

5:30 am - 12:59 pmCHS Charleston-PTY Panama City Tocumen Intl

8h 29m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

8h 35m1 stop Atlanta Hartsfield-Jackson

$619Delta

Mon, Oct 12 - Mon, Oct 19

5:10 am - 8:00 pmCHS Charleston-PTY Panama City Tocumen Intl

14h 50m1 stop Atlanta Hartsfield-Jackson

8:00 am - 3:26 pmPTY Panama City Tocumen Intl-CHS Charleston

7h 26m1 stop Atlanta Hartsfield-Jackson

$851Delta

Mon, Dec 21 - Tue, Dec 29

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American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets

American Airlines

Jan 20

CHS9:27 amCharleston

6h 11m

1 stop

PTY3:38 pmPanama City Tocumen Intl

Jan 28

PTY4:46 pmPanama City Tocumen Intl

7h 09m

1 stop

CHS11:55 pmCharleston

$602

American Airlines

Jan 20

CHS9:27 amCharleston

6h 11m

1 stop

PTY3:38 pmPanama City Tocumen Intl

Jan 28

PTY4:46 pmPanama City Tocumen Intl

17h 02m

2 stops

CHS9:48 amCharleston

$606

American Airlines

Oct 15

CHS4:34 pmCharleston

21h 28m

2 stops

PTY1:02 pmPanama City Tocumen Intl

Oct 20

PTY2:02 pmPanama City Tocumen Intl

8h 57m

1 stop

CHS11:59 pmCharleston

$623

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets

United Airlines

Oct 29

CHS6:30 amCharleston

13h 08m

1 stop

PTY6:38 pmPanama City Tocumen Intl

Nov 3

PTY10:00 amPanama City Tocumen Intl

13h 59m

1 stop

CHS11:59 pmCharleston

$597

United Airlines

Oct 29

CHS6:30 amCharleston

13h 08m

1 stop

PTY6:38 pmPanama City Tocumen Intl

Nov 3

PTY4:41 pmPanama City Tocumen Intl

21h 15m

2 stops

CHS1:56 pmCharleston

$601

United Airlines

Nov 20

CHS7:00 amCharleston

13h 02m

1 stop

PTY8:02 pmPanama City Tocumen Intl

Nov 24

PTY10:00 amPanama City Tocumen Intl

13h 59m

1 stop

CHS11:59 pmCharleston

$631

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Thu 1/14

10:10 am-2:10 am

2 stops16h 00m

Panama City Tocumen Intl

Tue 1/19

3:55 pm-9:20 am

2 stops17h 25m

$582

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Fri 12/4

7:40 am-2:10 am

2 stops18h 30m

Panama City Tocumen Intl

Sat 12/12

3:55 pm-11:52 am

2 stops19h 57m

$582

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Sat 12/5

7:40 am-2:10 am

2 stops18h 30m

Panama City Tocumen Intl

Sat 12/12

3:55 pm-11:52 am

2 stops19h 57m

$582

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Thu 11/5

6:00 am-1:59 pm

1 stop7h 59m

Panama City Tocumen Intl

Mon 11/9

3:29 pm-11:59 pm

1 stop8h 30m

$597

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Thu 10/29

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Tue 11/3

10:00 am-11:59 pm

1 stop13h 59m

$597

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Thu 10/29

7:04 pm-1:02 pm

2 stops18h 58m

Panama City Tocumen Intl

Tue 11/3

3:13 pm-11:24 am

2 stops20h 11m

$601

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Thu 10/29

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Tue 11/3

4:41 pm-1:56 pm

2 stops21h 15m

$601

Quickest round-trip

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Wed 1/20

7:15 am-3:55 pm

1 stop8h 40m

Panama City Tocumen Intl

Thu 1/28

4:55 pm-11:58 pm

1 stop7h 03m

$602

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Mon 10/12

5:30 am-12:59 pm

1 stop8h 29m

Panama City Tocumen Intl

Mon 10/19

2:24 pm-11:59 pm

1 stop8h 35m

$619

CharlestonPanama City

CHS Charleston - PTY Panama City Tocumen Intl

CHSPTY

Charleston

Mon 12/21

5:10 am-8:00 pm

1 stop14h 50m

Panama City Tocumen Intl

Tue 12/29

8:00 am-3:26 pm

1 stop7h 26m

$851

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $487. If you’re not able to fly to Panama City in March, then October is your next best option. Flight prices from Charleston to Panama City during October average around $510.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Best Price Found	$276
Fastest flight time	7h 59m
Direct flights	None

The best one-way flight to Panama City from Charleston in the past 72 hours is $276. The best round-trip flight deal from Charleston to Panama City found on momondo in the last 72 hours is $582.

The fastest flight from Charleston to Panama City takes 7h 59m

There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.

Search flight deals

Frequently asked questions about flying from Charleston to Panama City

How far is Charleston to Panama City Tocumen Intl by plane?
The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 7h 59m is a normal flight duration for this route.
When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?
Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.
How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?
As of September 2026, there are 3 operators available to choose from for flights from Charleston Airport to Panama City Tocumen Intl Airport.
How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Charleston to Panama City?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Charleston to Panama City is American Airlines (52% of total bookings). The next most popular airlines are Delta (24%) and United Airlines (24%).

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $299	Free Cancellation	Rating 7.8 8,538 reviews	Search Delta flights
United Airlines	PriceFrom $369	Free Cancellation	Rating 7.4 10,157 reviews	Search United Airlines flights
American Airlines	PriceFrom $399	Free Cancellation	Rating 7.1 12,023 reviews	Search American Airlines flights

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Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

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Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from Charleston to Panama City from $276

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 10/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets

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How to get the cheapest flight ticket from Charleston to Panama City

What is the cheapest month to fly to Panama City?

What is the cheapest airline that flies from Charleston to Panama City Tocumen Intl?

What airlines fly to Panama City?

Which airport is the most popular layover for flights between Charleston and Panama City?

Which layover airport offers the lowest fares from Charleston to Panama City?

Which layover airport has the shortest travel time from Charleston to Panama City?

Which layover airport has the shortest connection time from Charleston to Panama City?

When to book flights from Charleston to Panama City

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

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Frequently asked questions about flying from Charleston to Panama City

Best airlines flying from Charleston to Panama City

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An easier way to manage your Panama City trip

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List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

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