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Cheap flights from Charleston to Panama City from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama City departing on 4/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Charleston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:50 am - 6:37 pm
CHS
-
PTY
12h 47m
1 stop
United Airlines Logo
10:00 am - 10:15 pm
PTY
-
CHS
11h 15m
1 stop
$467United Airlines
Thu, Jun 18 - Wed, Jul 1
United Airlines Logo
6:50 am - 6:37 pm
CHS
-
PTY
12h 47m
1 stop
United Airlines Logo
10:55 pm - 9:48 pm
PTY
-
CHS
21h 53m
2 stops
$471United Airlines
Thu, Jun 18 - Wed, Jul 1
United Airlines Logo
5:08 pm - 4:12 pm
CHS
-
PTY
24h 04m
2 stops
United Airlines Logo
7:55 am - 11:59 pm
PTY
-
CHS
15h 04m
2 stops
$478United Airlines
Mon, May 11 - Wed, May 20
American Airlines Logo
8:09 pm - 12:46 pm
CHS
-
PTY
17h 37m
1 stop
American Airlines Logo
1:49 pm - 12:24 am
PTY
-
CHS
9h 35m
1 stop
$483American Airlines
Mon, May 11 - Wed, May 20
United Airlines Logo
6:50 am - 2:14 pm
CHS
-
PTY
8h 24m
1 stop
United Airlines Logo
7:55 am - 10:15 pm
PTY
-
CHS
13h 20m
1 stop
$494United Airlines
Fri, Jun 19 - Wed, Jul 1
United Airlines Logo
10:22 am - 4:04 am
CHS
-
PTY
18h 42m
2 stops
United Airlines Logo
10:00 am - 11:59 pm
PTY
-
CHS
12h 59m
2 stops
$498United Airlines
Sat, May 16 - Wed, May 20
United Airlines Logo
6:35 am - 6:37 pm
CHS
-
PTY
13h 02m
1 stop
United Airlines Logo
10:55 pm - 9:10 am
PTY
-
CHS
9h 15m
1 stop
$501United Airlines
Thu, May 14 - Sun, May 17
United Airlines Logo
11:15 am - 7:31 pm
CHS
-
PTY
9h 16m
1 stop
United Airlines Logo
3:30 pm - 10:15 pm
PTY
-
CHS
29h 45m
1 stop
$503United Airlines
Sat, May 16 - Wed, May 20
United Airlines Logo
6:00 am - 4:12 pm
CHS
-
PTY
11h 12m
2 stops
United Airlines Logo
3:30 pm - 12:17 pm
PTY
-
CHS
19h 47m
2 stops
$505United Airlines
Thu, May 14 - Sun, May 17
American Airlines Logo
5:04 pm - 12:46 pm
CHS
-
PTY
20h 42m
2 stops
American Airlines Logo
1:49 pm - 11:49 am
PTY
-
CHS
21h 00m
2 stops
$510American Airlines
Thu, May 14 - Sun, May 17

United Airlines flights from Charleston to Panama City

Our best United Airlines deals on Charleston to Panama City flight tickets
United Airlines
Jun 18
CHS6:50 amCharleston
12h 47m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jul 1
PTY10:00 amPanama City Tocumen Intl
11h 15m
1 stop
CHS10:15 pmCharleston
$467
United Airlines
Jun 18
CHS6:50 amCharleston
12h 47m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jun 30
PTY10:55 pmPanama City Tocumen Intl
21h 53m
2 stops
CHS9:48 pmCharleston
$471
United Airlines
May 11
CHS5:08 pmCharleston
24h 04m
2 stops
PTY4:12 pmPanama City Tocumen Intl
May 20
PTY7:55 amPanama City Tocumen Intl
15h 04m
2 stops
CHS11:59 pmCharleston
$478

American Airlines flights from Charleston to Panama City

Our best American Airlines deals on Charleston to Panama City flight tickets
American Airlines
May 11
CHS8:09 pmCharleston
17h 37m
1 stop
PTY12:46 pmPanama City Tocumen Intl
May 20
PTY1:49 pmPanama City Tocumen Intl
9h 35m
1 stop
CHS12:24 amCharleston
$483
American Airlines
May 14
CHS5:04 pmCharleston
20h 42m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 17
PTY1:49 pmPanama City Tocumen Intl
21h 00m
2 stops
CHS11:49 amCharleston
$510
American Airlines
Apr 19
CHS8:21 pmCharleston
17h 25m
2 stops
PTY12:46 pmPanama City Tocumen Intl
Apr 22
PTY1:49 pmPanama City Tocumen Intl
19h 45m
1 stop
CHS10:34 amCharleston
$556

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 6/18

6:50 am-6:37 pm

1 stop12h 47m

Panama City Tocumen Intl

Wed 7/1

10:00 am-10:15 pm

1 stop11h 15m

$467

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 6/18

6:50 am-6:37 pm

1 stop12h 47m

Panama City Tocumen Intl

Wed 7/1

10:55 pm-9:48 pm

2 stops21h 53m

$471

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 5/11

5:08 pm-4:12 pm

2 stops24h 04m

Panama City Tocumen Intl

Wed 5/20

7:55 am-11:59 pm

2 stops15h 04m

$478

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 5/11

8:09 pm-12:46 pm

1 stop17h 37m

Panama City Tocumen Intl

Wed 5/20

1:49 pm-12:24 am

1 stop9h 35m

$483
Quickest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 6/19

6:50 am-2:14 pm

1 stop8h 24m

Panama City Tocumen Intl

Wed 7/1

7:55 am-10:15 pm

1 stop13h 20m

$494

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 5/16

10:22 am-4:04 am

2 stops18h 42m

Panama City Tocumen Intl

Wed 5/20

10:00 am-11:59 pm

2 stops12h 59m

$498

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 5/14

6:35 am-6:37 pm

1 stop13h 02m

Panama City Tocumen Intl

Sun 5/17

10:55 pm-9:10 am

1 stop9h 15m

$501

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 5/16

11:15 am-7:31 pm

1 stop9h 16m

Panama City Tocumen Intl

Wed 5/20

3:30 pm-10:15 pm

1 stop29h 45m

$503

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 5/14

6:00 am-4:12 pm

2 stops11h 12m

Panama City Tocumen Intl

Sun 5/17

3:30 pm-12:17 pm

2 stops19h 47m

$505

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 5/14

5:04 pm-12:46 pm

2 stops20h 42m

Panama City Tocumen Intl

Sun 5/17

1:49 pm-11:49 am

2 stops21h 00m

$510

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Charleston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Charleston and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Charleston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $389. If you’re not able to fly to Panama City in September, then May is your next best option. Flight prices from Charleston to Panama City during May average around $440.

Can stopping save me money on Charleston to Panama City flights?

You could potentially save up to 75% on your flight if you consider stops on a Charleston to Panama City flight.

When to book flights from Charleston to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Panama City (CHS to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama City

Fastest flight time

9h 13m

Direct flights

None
The fastest flight from Charleston to Panama City takes 9h 13m
There are no direct flights from Charleston to Panama City. There are no popular flight routes from Charleston to Panama City.
Search flight deals

  • How far is Charleston to Panama City Tocumen Intl by plane?

    The straight-line distance from Charleston to Panama City Tocumen Intl is 1643.0 mi. 9h 13m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Charleston Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Charleston Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Charleston Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Charleston to Panama City?

Best airlines flying from Charleston to Panama City

Compare and see reviews for airlines that fly from Charleston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $309Free CancellationRating
7.9
8,359 reviews
Search Delta flights
American AirlinesPriceFrom $363Free CancellationRating
7.1
11,530 reviews
Search American Airlines flights
United AirlinesPriceFrom $369Free CancellationRating
7.4
9,514 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Panama City with flexible booking policies on momondo?

Flights from Charleston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Charleston. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Charleston to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Charleston to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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