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Cheap flights from Charleston to Guayaquil from $451

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Guayaquil departing on 10/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Charleston to Guayaquil (CHS-GYE)

Cheap round-trip flights

JetBlue Logo
9:40 am - 1:30 pmCHS-GYE
28h 50m1 stop
JetBlue Logo
2:40 pm - 8:54 amGYE-CHS
17h 14m1 stop
$451JetBlue
Find Deal
Tue, Oct 7 - Fri, Oct 17
Delta Logo
6:00 am - 2:05 amCHS-GYE
20h 05m2 stops
Delta Logo
4:00 pm - 11:52 amGYE-CHS
19h 52m1 stop
$483Delta
Find Deal
Wed, Feb 4 - Sat, Feb 14
American Airlines Logo
7:44 pm - 7:10 pmCHS-GYE
24h 26m1 stop
American Airlines Logo
8:15 am - 10:49 amGYE-CHS
25h 34m2 stops
$569American Airlines
Find Deal
Wed, Oct 8 - Wed, Oct 15
United Airlines Logo
5:16 pm - 1:46 pmCHS-GYE
45h 30m2 stops
United Airlines Logo
2:47 pm - 4:39 pmGYE-CHS
48h 52m2 stops
$604United Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
United Airlines Logo
7:00 am - 11:37 pmCHS-GYE
17h 37m2 stops
United Airlines Logo
12:15 pm - 4:44 pmGYE-CHS
27h 29m2 stops
$610United Airlines
Find Deal
Tue, Oct 7 - Fri, Oct 17
Logo
6:30 am - 7:40 amCHS-GYE
25h 10m2 stops
Logo
2:35 pm - 11:42 pmGYE-CHS
33h 07m2 stops
$619
Find Deal
Wed, Nov 12 - Sat, Nov 22
LATAM Airlines Logo
6:40 am - 7:05 amCHS-GYE
25h 25m2 stops
LATAM Airlines Logo
8:25 pm - 10:21 amGYE-CHS
12h 56m2 stops
$637LATAM Airlines
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Wed, Oct 8 - Wed, Oct 15
American Airlines Logo
7:44 pm - 7:10 pmCHS-GYE
24h 26m1 stop
American Airlines Logo
8:15 am - 11:59 pmGYE-CHS
14h 44m1 stop
$664American Airlines
Find Deal
Wed, Oct 8 - Wed, Oct 15
LATAM Airlines Logo
6:59 pm - 5:53 pmCHS-GYE
47h 54m2 stops
LATAM Airlines Logo
8:56 pm - 9:16 amGYE-CHS
11h 20m2 stops
$696LATAM Airlines
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Tue, Sep 23 - Tue, Sep 30
Logo
11:04 am - 1:46 pmCHS-GYE
51h 42m2 stops
Logo
3:35 am - 11:43 pmGYE-CHS
19h 08m2 stops
$712
Find Deal
Tue, Sep 16 - Thu, Sep 25

JetBlue flights from Charleston to Guayaquil

Our best JetBlue deals on Charleston to Guayaquil flight tickets
JetBlue
Oct 7
CHS9:40 amCharleston
28h 50m
1 stop
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
Oct 17
GYE2:40 pmGuayaquil Jose Joaquin de Olmedo
17h 14m
1 stop
CHS8:54 amCharleston
$451
Find similar
JetBlue
Oct 7
CHS11:10 amCharleston
27h 20m
2 stops
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
Oct 17
GYE2:40 pmGuayaquil Jose Joaquin de Olmedo
17h 14m
1 stop
CHS8:54 amCharleston
$505
Find similar
JetBlue
Nov 22
CHS5:47 pmCharleston
20h 33m
1 stop
GYE2:20 pmGuayaquil Jose Joaquin de Olmedo
Dec 1
GYE3:30 pmGuayaquil Jose Joaquin de Olmedo
17h 05m
1 stop
CHS8:35 amCharleston
$660
Find similar

Delta flights from Charleston to Guayaquil

Our best Delta deals on Charleston to Guayaquil flight tickets
Delta
Feb 4
CHS6:00 amCharleston
20h 05m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
Feb 14
GYE4:00 pmGuayaquil Jose Joaquin de Olmedo
19h 52m
1 stop
CHS11:52 amCharleston
$483
Find similar
Delta
Feb 4
CHS6:00 amCharleston
20h 05m
2 stops
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
Feb 14
GYE4:00 pmGuayaquil Jose Joaquin de Olmedo
19h 25m
2 stops
CHS11:25 amCharleston
$646
Find similar
Delta
Feb 4
CHS12:45 pmCharleston
18h 35m
1 stop
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
Feb 14
GYE4:00 pmGuayaquil Jose Joaquin de Olmedo
19h 52m
1 stop
CHS11:52 amCharleston
$1,113
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from Charleston to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 10/7

9:40 am-1:30 pm

1 stop28h 50m

Guayaquil Jose Joaquin de Olmedo

Fri 10/17

2:40 pm-8:54 am

1 stop17h 14m

$451

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 2/4

6:00 am-2:05 am

2 stops20h 05m

Guayaquil Jose Joaquin de Olmedo

Sat 2/14

4:00 pm-11:52 am

1 stop19h 52m

$483

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 10/8

7:44 pm-7:10 pm

1 stop24h 26m

Guayaquil Jose Joaquin de Olmedo

Wed 10/15

8:15 am-10:49 am

2 stops25h 34m

$569

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 9/23

5:16 pm-1:46 pm

2 stops45h 30m

Guayaquil Jose Joaquin de Olmedo

Tue 9/30

2:47 pm-4:39 pm

2 stops48h 52m

$604

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 10/7

7:00 am-11:37 pm

2 stops17h 37m

Guayaquil Jose Joaquin de Olmedo

Fri 10/17

12:15 pm-4:44 pm

2 stops27h 29m

$610

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 11/12

6:30 am-7:40 am

2 stops25h 10m

Guayaquil Jose Joaquin de Olmedo

Sat 11/22

2:35 pm-11:42 pm

2 stops33h 07m

$619

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 10/8

6:40 am-7:05 am

2 stops25h 25m

Guayaquil Jose Joaquin de Olmedo

Wed 10/15

8:25 pm-10:21 am

2 stops12h 56m

$637

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Wed 10/8

7:44 pm-7:10 pm

1 stop24h 26m

Guayaquil Jose Joaquin de Olmedo

Wed 10/15

8:15 am-11:59 pm

1 stop14h 44m

$664

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 9/23

6:59 pm-5:53 pm

2 stops47h 54m

Guayaquil Jose Joaquin de Olmedo

Tue 9/30

8:56 pm-9:16 am

2 stops11h 20m

$696

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 9/16

11:04 am-1:46 pm

2 stops51h 42m

Guayaquil Jose Joaquin de Olmedo

Thu 9/25

3:35 am-11:43 pm

2 stops19h 08m

$712

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Guayaquil from

How to get the cheapest flight ticket from Charleston to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from Charleston to Guayaquil is on a Saturday. Travelers who choose to depart for Guayaquil on a Saturday will often find tickets for as low as $516. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Friday is $657.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the morning when flights can be purchased for as low as $516. Flights to Guayaquil are more costly in the afternoon, with an average ticket price of $624. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Charleston to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Guayaquil (CHS to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Guayaquil

Best Price Found

$451

Fastest flight time

9h 41m

Direct flights

None

Airports in Guayaquil

1 airport
The best flight deal from Charleston to Guayaquil found on momondo in the last 72 hours is $451
The fastest flight from Charleston to Guayaquil takes 9h 41m
There are no direct flights from Charleston to Guayaquil. Popular non-direct route for this connection is Charleston Airport - Guayaquil Jose Joaquin de Olmedo Airport.
There is 1 airport near Guayaquil: Guayaquil Jose Joaquin de Olmedo (GYE)
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  • How far is Charleston to Guayaquil Jose Joaquin de Olmedo by plane?

    Guayaquil Jose Joaquin de Olmedo is 2414.5 mi away from Charleston. In terms of flight time, this usually takes a little over 9h 41m.

  • When did momondo last update prices for flights from Charleston Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Charleston Airport to Guayaquil Jose Joaquin de Olmedo Airport were last updated today.

  • How many operators does momondo search for flights from Charleston Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from Charleston Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents you'll need for your trip to Guayaquil Jose Joaquin de Olmedo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Charleston to Guayaquil?

Best airlines flying from Charleston to Guayaquil

Compare and see reviews for airlines that fly from Charleston to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $451Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Guayaquil?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Charleston to Guayaquil. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Charleston to Guayaquil with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Charleston to Guayaquil flights to just show those with flexible booking policies.

How can momondo help me find flights from Charleston to Guayaquil?

Once you have performed a search for Charleston to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Charleston to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from Charleston. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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