Cheap flights from Charleston to Cusco from $558

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Cusco departing on 4/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
3:28 pm - 11:20 am
CHS
-
CUZ
20h 52m
2 stops
Multiple Airlines Logo
5:55 pm - 9:04 pm
CUZ
-
CHS
26h 09m
3 stops
$881Multiple Airlines
Tue, Aug 25 - Tue, Sep 8
American Airlines Logo
8:08 pm - 7:25 pm
CHS
-
CUZ
24h 17m
2 stops
American Airlines Logo
12:45 pm - 10:13 am
CUZ
-
CHS
20h 28m
2 stops
$890American Airlines
Wed, Jul 1 - Thu, Jul 16
Multiple Airlines Logo
7:40 pm - 4:05 pm
CHS
-
CUZ
21h 25m
3 stops
Multiple Airlines Logo
5:55 pm - 9:04 pm
CUZ
-
CHS
26h 09m
3 stops
$938Multiple Airlines
Tue, Aug 25 - Tue, Sep 8
LATAM Airlines Logo
12:15 pm - 11:35 am
CHS
-
CUZ
24h 20m
3 stops
LATAM Airlines Logo
8:25 am - 11:57 pm
CUZ
-
CHS
14h 32m
2 stops
$1,014LATAM Airlines
Wed, Jul 1 - Thu, Jul 16
LATAM Airlines Logo
7:30 am - 11:25 pm
CHS
-
CUZ
16h 55m
3 stops
LATAM Airlines Logo
5:00 am - 11:57 pm
CUZ
-
CHS
17h 57m
3 stops
$1,043LATAM Airlines
Wed, Jul 1 - Thu, Jul 16
LATAM Airlines Logo
7:58 pm - 6:10 am
CHS
-
CUZ
35h 12m
2 stops
LATAM Airlines Logo
7:30 am - 8:51 am
CUZ
-
CHS
24h 21m
2 stops
$1,090LATAM Airlines
Fri, Apr 3 - Tue, Apr 14
American Airlines Logo
8:08 pm - 3:25 pm
CHS
-
CUZ
20h 17m
2 stops
American Airlines Logo
10:00 pm - 7:37 pm
CUZ
-
CHS
20h 37m
2 stops
$1,114American Airlines
Fri, Apr 3 - Wed, Apr 15
LATAM Airlines Logo
7:58 pm - 11:25 pm
CHS
-
CUZ
28h 27m
3 stops
LATAM Airlines Logo
8:25 am - 11:50 pm
CUZ
-
CHS
14h 25m
2 stops
$1,160LATAM Airlines
Fri, Apr 3 - Tue, Apr 14
LATAM Airlines Logo
7:58 pm - 11:25 pm
CHS
-
CUZ
28h 27m
3 stops
LATAM Airlines Logo
12:05 am - 11:50 pm
CUZ
-
CHS
22h 45m
3 stops
$1,176LATAM Airlines
Fri, Apr 3 - Mon, Apr 13
LATAM Airlines Logo
7:58 pm - 11:25 pm
CHS
-
CUZ
28h 27m
3 stops
LATAM Airlines Logo
8:25 am - 11:50 pm
CUZ
-
CHS
14h 25m
2 stops
$1,229LATAM Airlines
Fri, Apr 3 - Wed, Apr 15

LATAM Airlines flights from Charleston to Cusco

Our best LATAM Airlines deals on Charleston to Cusco flight tickets
LATAM Airlines
Jul 1
CHS12:15 pmCharleston
24h 20m
3 stops
CUZ11:35 amCusco Velazco Astete
Jul 16
CUZ8:25 amCusco Velazco Astete
14h 32m
2 stops
CHS11:57 pmCharleston
$1,014
LATAM Airlines
Jul 1
CHS7:30 amCharleston
16h 55m
3 stops
CUZ11:25 pmCusco Velazco Astete
Jul 16
CUZ5:00 amCusco Velazco Astete
17h 57m
3 stops
CHS11:57 pmCharleston
$1,043
LATAM Airlines
Apr 3
CHS7:58 pmCharleston
35h 12m
2 stops
CUZ6:10 amCusco Velazco Astete
Apr 14
CUZ7:30 amCusco Velazco Astete
24h 21m
2 stops
CHS8:51 amCharleston
$1,090

American Airlines flights from Charleston to Cusco

Our best American Airlines deals on Charleston to Cusco flight tickets
American Airlines
Jul 1
CHS8:08 pmCharleston
24h 17m
2 stops
CUZ7:25 pmCusco Velazco Astete
Jul 16
CUZ12:45 pmCusco Velazco Astete
20h 28m
2 stops
CHS10:13 amCharleston
$890
American Airlines
Apr 3
CHS8:08 pmCharleston
20h 17m
2 stops
CUZ3:25 pmCusco Velazco Astete
Apr 15
CUZ10:00 pmCusco Velazco Astete
20h 37m
2 stops
CHS7:37 pmCharleston
$1,114

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Cusco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Charleston to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Tue 8/25

3:28 pm-11:20 am

2 stops20h 52m

Cusco Velazco Astete

Tue 9/8

5:55 pm-9:04 pm

3 stops26h 09m

$881

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Wed 7/1

8:08 pm-7:25 pm

2 stops24h 17m

Cusco Velazco Astete

Thu 7/16

12:45 pm-10:13 am

2 stops20h 28m

$890

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Tue 8/25

7:40 pm-4:05 pm

3 stops21h 25m

Cusco Velazco Astete

Tue 9/8

5:55 pm-9:04 pm

3 stops26h 09m

$938

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Wed 7/1

12:15 pm-11:35 am

3 stops24h 20m

Cusco Velazco Astete

Thu 7/16

8:25 am-11:57 pm

2 stops14h 32m

$1,014

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Wed 7/1

7:30 am-11:25 pm

3 stops16h 55m

Cusco Velazco Astete

Thu 7/16

5:00 am-11:57 pm

3 stops17h 57m

$1,043

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 4/3

7:58 pm-6:10 am

2 stops35h 12m

Cusco Velazco Astete

Tue 4/14

7:30 am-8:51 am

2 stops24h 21m

$1,090

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 4/3

8:08 pm-3:25 pm

2 stops20h 17m

Cusco Velazco Astete

Wed 4/15

10:00 pm-7:37 pm

2 stops20h 37m

$1,114

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 4/3

7:58 pm-11:25 pm

3 stops28h 27m

Cusco Velazco Astete

Tue 4/14

8:25 am-11:50 pm

2 stops14h 25m

$1,160

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 4/3

7:58 pm-11:25 pm

3 stops28h 27m

Cusco Velazco Astete

Mon 4/13

12:05 am-11:50 pm

3 stops22h 45m

$1,176

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 4/3

7:58 pm-11:25 pm

3 stops28h 27m

Cusco Velazco Astete

Wed 4/15

8:25 am-11:50 pm

2 stops14h 25m

$1,229

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Cusco from

How to get the cheapest flight ticket from Charleston to Cusco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Charleston to Cusco Velazco Astete?

LATAM Airlines is the most popular carrier operating from Charleston to Cusco Velazco Astete

When to book flights from Charleston to Cusco

Are you open to changing your travel dates? Check out the ideal times to fly from Charleston to Cusco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Charleston to Cusco (CHS to CUZ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Cusco

Fastest flight time

17h 25m

Direct flights

None
The fastest flight from Charleston to Cusco takes 17h 25m
There are no direct flights from Charleston to Cusco. There are no popular flight routes from Charleston to Cusco.
  • How far is Charleston to Cusco Velazco Astete by plane?

    Charleston and Cusco Velazco Astete are 3240.3 mi apart from one another. Flights usually cover this in 17h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Charleston Airport to Cusco Velazco Astete Airport?

    Prices for flights from Charleston Airport to Cusco Velazco Astete Airport are updated daily.

  • How old do you have to be to fly from Charleston Airport to Cusco Velazco Astete Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Charleston Airport to Cusco Velazco Astete Airport.

  • What documentation or ID do you need to fly to Cusco Velazco Astete Airport?

    The travel and health documents you'll need for your trip to Cusco Velazco Astete Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Cusco Velazco Astete Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Machu Picchu
Urubamba
Ollantaytambo

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Cusco?

It is quick and easy to find Charleston to Cusco flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Cusco that suits you.

Can I find flights from Charleston to Cusco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Cusco from Charleston with this policy.

How can momondo help me find flights from Charleston to Cusco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Cusco from Charleston.

I’m not ready to book a flight from Charleston to Cusco right now. Can momondo alert me if prices change?

Price alerts on flights to Cusco from Charleston are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Sun 3/29
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