St. Louis Holiday Inn Express hotel is near the Barnes Jewish Hospital. Enjoy your stay at Holiday Inn Express St. Louis Central West End. Whether traveling for business or a visit to experience the community, this highly recommended, midtown, St. Louis hotel provides premium guest amenities, excellent service, and convenient access to dining and local attractions. We are confident you will enjoy staying at our smoke-free, historic hotel as it is less than a mile away from the nationally known St. Louis Forest Park. Surrounded by a historic and among 10 best places to live. The neighborhood includes the renowned Barnes Jewish Hospital and Washington University Medical Center. After a short trip, situated nearly just 11 miles from the St. Louis Lambert Airport, relax inside the comforts of our newly renovated hotel rooms, and visit local attractions including St. Louis Zoo, St. Louis Science Center, World Chess Hall of Fame and the St. Louis Gateway Arch monument. Hotel accommodations are well suited to most business travelers as we are located near AT&T, Ab-InBev, St. Louis University, Washington University & the Cortex business district. Grab & Go Breakfast is on us to start your day and stay on track with our 24-hour Fitness Center. Experience a memorable stay in this historic Central West End landmark. Make your reservations today at the Holiday Inn Express Central West End.