Welcome to the Holiday Inn Express and Suites, One of the Finest Clemson Hotels. Enjoy your stay at a state-of-the-art hotel in Clemson with cosmic, Clemson Tiger decor. Our Holiday Inn Express and Suites Clemson hotel is located at 1381 Tiger Blvd (HWY 123), minutes from Clemson University, home of the 2018 National Champion, Clemson Tigers! Our Holiday Inn Express of Clemson is located near the towns of Anderson, Central, Seneca, Easley, Liberty, Six Miles, Walhalla, Pickens and Westminster. Nearby attractions include Southern Wesleyan University, SC Botanical Garden, Lake Hartwell, Brooks Center for the Performing Arts, T. Ed Garrison Arena, Death Valley, and Little John Coliseum. Business travelers enjoy our location and corporate amenities, too. We are only minutes from Duke Energy, Reliable Sprinkler, Michelin, Milliken, Pickens Corporate Park, BASF, and Madren Conference Center. Our Clemson hotel has a 24-hour Business Center with copy and fax services, as well as a 1,300-square feet meeting room, which can accommodate up to 60 people. We offer great amenities to please leisure and business travelers, such as a free, hot breakfast bar, outdoor deck seating, a sun deck, a well-equipped Fitness Center and Wi-Fi Internet access. Stay at one of the finest hotels in Clemson, and enjoy our contemporary, well-appointed lobby, and a friendly staff waiting to show you real Southern hospitality. Must be 21 to register.