Cheap flights from St. Louis to Brussels from $455
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Brussels departing on 3/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Our best Scandinavian Airlines deals on St. Louis to Brussels Bruxelles-National Airport flight tickets
Lufthansa flights from St. Louis to Brussels Bruxelles-National Airport
Our best Lufthansa deals on St. Louis to Brussels Bruxelles-National Airport flight tickets
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Use the filters below to find and compare flights from St. Louis to Brussels Bruxelles-National Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Mon 11/9
1:58 pm-11:10 am
2 stops14h 12m
Brussels Bruxelles-National
Wed 11/18
2:00 pm-11:59 pm
2 stops16h 59m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Mon 11/9
4:05 pm-1:15 pm
2 stops14h 10m
Brussels Bruxelles-National
Wed 11/18
7:00 am-1:45 pm
1 stop13h 45m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Tue 12/1
4:05 pm-8:10 pm
2 stops21h 05m
Brussels Bruxelles-National
Fri 12/11
10:00 am-9:29 pm
2 stops42h 29m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Tue 12/1
10:50 am-1:15 pm
2 stops19h 25m
Brussels Bruxelles-National
Fri 12/11
7:00 am-1:45 pm
1 stop13h 45m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Mon 11/9
3:15 pm-8:55 am
1 stop10h 40m
Brussels Bruxelles-National
Wed 11/18
10:10 am-9:40 pm
1 stop18h 30m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Tue 12/1
6:00 am-8:05 am
1 stop19h 05m
Brussels Bruxelles-National
Fri 12/11
7:00 am-1:45 pm
1 stop13h 45m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Fri 2/5
6:45 pm-7:50 am
2 stops54h 05m
Brussels Bruxelles-National
Mon 7/5
10:50 am-12:16 am
2 stops20h 26m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Wed 10/28
4:40 pm-5:30 pm
1 stop18h 50m
Brussels Bruxelles-National
Wed 11/11
8:25 am-1:45 pm
1 stop12h 20m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Wed 3/17
4:40 pm-10:10 am
1 stop11h 30m
Brussels Bruxelles-National
Sat 3/27
5:05 pm-1:25 pm
1 stop26h 20m
St. LouisBrussels
STL Lambert-St Louis - BRU Brussels Bruxelles-National
STLBRU
Lambert-St Louis
Wed 3/17
4:40 pm-10:10 am
1 stop11h 30m
Brussels Bruxelles-National
Sat 3/27
5:05 pm-1:25 pm
1 stop26h 20m
See travel insights to Brussels from
How to get the cheapest flight ticket from St. Louis to Brussels Bruxelles-National Airport
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Brussels Bruxelles-National Airport?
The cheapest month to fly to Brussels Bruxelles-National Airport from St. Louis is in February. Flight prices, which tend to average around $494, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Brussels Bruxelles-National Airport from St. Louis during January instead. Flights to Brussels Bruxelles-National Airport in January, while not as cheap as those in February, still average around $657.
Can stopping save me money on St. Louis to Brussels Bruxelles-National Airport flights?
You could potentially save up to 14% on your flight if you consider stops on a St. Louis to Brussels Bruxelles-National Airport flight.
Which airport is the most popular layover for flights between St. Louis and Brussels Bruxelles-National Airport?
Chicago (ORD) was the most common stop: 56% of momondo users choosing 1-stop flights on this route connected there.
Which layover airport offers the lowest fares from St. Louis to Brussels Bruxelles-National Airport?
Flights via Frankfurt am Main (FRA) offer the lowest average round-trip price of $942.
Which layover airport has the shortest travel time from St. Louis to Brussels Bruxelles-National Airport?
Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 11h 18m.
Which layover airport has the shortest connection time from St. Louis to Brussels Bruxelles-National Airport?
Frankfurt am Main (FRA) has the shortest average layover time for this route: 1h 23m.
When to book flights from St. Louis to Brussels Bruxelles-National Airport
Cheap St. Louis to Brussels Bruxelles-National Airport (STL to BRU) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from St. Louis to Brussels Bruxelles-National Airport
Frequently asked questions about flying from St. Louis to Brussels Bruxelles-National Airport
How far is Lambert-St Louis to Brussels Bruxelles-National by plane?
The straight-line distance from Lambert-St Louis to Brussels Bruxelles-National is 4393.0 mi. Flights usually cover this in 13h 55m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Lambert-St Louis Airport to Brussels Bruxelles-National Airport?
Prices for flights from Lambert-St Louis Airport to Brussels Bruxelles-National Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Lambert-St Louis Airport to Brussels Bruxelles-National Airport?
As of October 2026, there are 2 operators available to choose from for flights from Lambert-St Louis Airport to Brussels Bruxelles-National Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Brussels Bruxelles-National Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Lambert-St Louis Airport to Brussels Bruxelles-National Airport.
What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?
The travel and health documents required for your trip to Brussels Bruxelles-National Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Brussels Bruxelles-National Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from St. Louis to Brussels Bruxelles-National Airport?
Based on momondo bookings for flights between St. Louis and Brussels Bruxelles-National Airport, the leading airline is United Airlines, making up 76% of the total bookings. Other popular airlines include Lufthansa with 24%.
Best airlines flying from St. Louis to Brussels Bruxelles-National Airport
Compare and see reviews for airlines that fly from St. Louis to Brussels Bruxelles-National Airport with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $441 | Free Cancellation | Rating 6.8 8,269 reviews | |||
| PriceFrom $507 | Free Cancellation | Rating 7.4 10,332 reviews |
Traveling to a place near Brussels?
Book flights to Brussels if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from St. Louis to Brussels?
To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Brussels from St. Louis.
Can I find flights from St. Louis to Brussels with flexible booking policies on momondo?
momondo does allow users to show only those flights to Brussels from St. Louis which offer a flexible booking policy as well as other useful filters and features.
How can momondo help me find flights from St. Louis to Brussels?
Once all potential St. Louis to Brussels flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.
I’m not ready to book a flight from St. Louis to Brussels right now. Can momondo alert me if prices change?
Yes momondo offers price alerts on flights to Brussels from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.