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Cheap flights from South Carolina to Medellín from $91

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Medellín departing on 3/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from South Carolina to Medellín

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
9:24 pm - 1:13 pm
CLT
-
MDE
16h 49m
1 stop
Spirit Airlines Logo
2:10 pm - 12:40 am
MDE
-
CLT
9h 30m
1 stop
$231Spirit Airlines
Tue, Apr 28 - Wed, May 6
Spirit Airlines Logo
9:24 pm - 1:13 pm
CLT
-
MDE
16h 49m
1 stop
Spirit Airlines Logo
2:10 pm - 12:40 am
MDE
-
CLT
9h 30m
1 stop
$236Spirit Airlines
Sun, May 10 - Sat, May 16
Spirit Airlines Logo
9:00 pm - 1:22 pm
CLT
-
MDE
17h 22m
1 stop
Spirit Airlines Logo
2:17 pm - 8:21 am
MDE
-
CLT
17h 04m
1 stop
$242Spirit Airlines
Sun, Mar 29 - Tue, Apr 7
Multiple Airlines Logo
9:28 pm - 12:55 pm
CLT
-
MDE
16h 27m
1 stop
Multiple Airlines Logo
1:52 pm - 8:03 am
MDE
-
CLT
17h 11m
1 stop
$253Multiple Airlines
Mon, Mar 9 - Tue, Mar 17
Multiple Airlines Logo
12:47 pm - 12:21 am
SAV
-
MDE
12h 34m
1 stop
Multiple Airlines Logo
1:17 am - 9:54 pm
MDE
-
SAV
19h 37m
1 stop
$278Multiple Airlines
Mon, Mar 30 - Sun, Apr 5
United Airlines Logo
5:45 am - 9:10 pm
SAV
-
MDE
16h 25m
2 stops
United Airlines Logo
9:45 am - 10:44 am
MDE
-
SAV
23h 59m
2 stops
$566United Airlines
Fri, May 8 - Sun, May 17
American Airlines Logo
5:19 pm - 1:06 pm
HHH
-
MDE
20h 47m
2 stops
American Airlines Logo
12:20 am - 3:01 pm
MDE
-
HHH
13h 41m
2 stops
$568American Airlines
Tue, Mar 24 - Mon, Mar 30
United Airlines Logo
7:00 am - 9:10 pm
SAV
-
MDE
15h 10m
1 stop
United Airlines Logo
9:45 am - 9:59 pm
MDE
-
SAV
11h 14m
1 stop
$573United Airlines
Fri, May 8 - Sun, May 17
American Airlines Logo
10:52 am - 8:15 pm
SAV
-
MDE
10h 23m
1 stop
American Airlines Logo
1:53 pm - 8:34 am
MDE
-
SAV
17h 41m
2 stops
$588American Airlines
Fri, May 8 - Sun, May 17
JetBlue Logo
5:21 pm - 2:45 pm
SAV
-
MDE
21h 24m
2 stops
JetBlue Logo
1:25 pm - 12:58 pm
MDE
-
SAV
22h 33m
2 stops
$667JetBlue
Tue, Mar 3 - Fri, Mar 20

Spirit Airlines flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best Spirit Airlines deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
Spirit Airlines
Apr 28
CLT9:24 pmCharlotte Douglas
16h 49m
1 stop
MDE1:13 pmMedellín Jose Maria Cordova Intl
May 6
MDE2:10 pmMedellín Jose Maria Cordova Intl
9h 30m
1 stop
CLT12:40 amCharlotte Douglas
$231
Spirit Airlines
May 10
CLT9:24 pmCharlotte Douglas
16h 49m
1 stop
MDE1:13 pmMedellín Jose Maria Cordova Intl
May 16
MDE2:10 pmMedellín Jose Maria Cordova Intl
9h 30m
1 stop
CLT12:40 amCharlotte Douglas
$236
Spirit Airlines
Mar 29
CLT9:00 pmCharlotte Douglas
17h 22m
1 stop
MDE1:22 pmMedellín Jose Maria Cordova Intl
Apr 7
MDE2:17 pmMedellín Jose Maria Cordova Intl
17h 04m
1 stop
CLT8:21 amCharlotte Douglas
$242

American Airlines flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best American Airlines deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
American Airlines
Mar 25
GSP6:40 amGreenville
14h 30m
1 stop
MDE8:10 pmMedellín Jose Maria Cordova Intl
Apr 1
MDE2:10 pmMedellín Jose Maria Cordova Intl
9h 11m
1 stop
GSP12:21 amGreenville
$540
American Airlines
Mar 25
GSP9:03 amGreenville
14h 36m
2 stops
MDE10:39 pmMedellín Jose Maria Cordova Intl
Apr 1
MDE6:00 amMedellín Jose Maria Cordova Intl
17h 21m
1 stop
GSP12:21 amGreenville
$545
American Airlines
May 15
GSP6:45 pmGreenville
19h 03m
1 stop
MDE12:48 pmMedellín Jose Maria Cordova Intl
May 23
MDE12:30 amMedellín Jose Maria Cordova Intl
18h 07m
1 stop
GSP7:37 pmGreenville
$550

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 4/28

9:24 pm-1:13 pm

1 stop16h 49m

Medellín Jose Maria Cordova Intl

Wed 5/6

2:10 pm-12:40 am

1 stop9h 30m

$231

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sun 5/10

9:24 pm-1:13 pm

1 stop16h 49m

Medellín Jose Maria Cordova Intl

Sat 5/16

2:10 pm-12:40 am

1 stop9h 30m

$236

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sun 3/29

9:00 pm-1:22 pm

1 stop17h 22m

Medellín Jose Maria Cordova Intl

Tue 4/7

2:17 pm-8:21 am

1 stop17h 04m

$242

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 3/9

9:28 pm-12:55 pm

1 stop16h 27m

Medellín Jose Maria Cordova Intl

Tue 3/17

1:52 pm-8:03 am

1 stop17h 11m

$253

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Mon 3/30

12:47 pm-12:21 am

1 stop12h 34m

Medellín Jose Maria Cordova Intl

Sun 4/5

1:17 am-9:54 pm

1 stop19h 37m

$278

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Fri 5/8

5:45 am-9:10 pm

2 stops16h 25m

Medellín Jose Maria Cordova Intl

Sun 5/17

9:45 am-10:44 am

2 stops23h 59m

$566

Hilton Head IslandMedellín

HHH - MDE

HHHMDE

Hilton Head Island

Tue 3/24

5:19 pm-1:06 pm

2 stops20h 47m

Medellín Jose Maria Cordova Intl

Mon 3/30

12:20 am-3:01 pm

2 stops13h 41m

$568

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Fri 5/8

7:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

Sun 5/17

9:45 am-9:59 pm

1 stop11h 14m

$573

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Fri 5/8

10:52 am-8:15 pm

1 stop10h 23m

Medellín Jose Maria Cordova Intl

Sun 5/17

1:53 pm-8:34 am

2 stops17h 41m

$588

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Tue 3/3

5:21 pm-2:45 pm

2 stops21h 24m

Medellín Jose Maria Cordova Intl

Fri 3/20

1:25 pm-12:58 pm

2 stops22h 33m

$667

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Medellín from

How to get the cheapest flight ticket from South Carolina to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, September is the cheapest month to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $399. If you aren’t able to travel during the month of September, then book flights to Medellín Jose Maria Cordova Intl Airport from South Carolina during March instead. Flights to Medellín Jose Maria Cordova Intl Airport in March, while not as cheap as those in September, still average around $523.

Can stopping save me money on South Carolina to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 12% on your flight if you consider stops on a South Carolina to Medellín Jose Maria Cordova Intl Airport flight.

Cheap South Carolina to Medellín Jose Maria Cordova Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Medellín Jose Maria Cordova Intl Airport

Fastest flight time

6h 15m

Direct flights

None
The fastest flight from South Carolina to Medellín Jose Maria Cordova Intl Airport takes 6h 15m
There are no direct flights from South Carolina to Medellín Jose Maria Cordova Intl Airport. There are no popular flight routes from South Carolina to Medellín Jose Maria Cordova Intl Airport.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The required travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $327Free CancellationRating
6.3
8,430 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $515Free CancellationRating
7.2
11,258 reviews
Search American Airlines flights

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Medellín?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Medellín. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Medellín with flexible booking policies on momondo?

Yes. All flights to Medellín from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Medellín?

momondo helps you find the best flight between South Carolina and Medellín by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Medellín right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Medellín flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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