Cheap flights from South Carolina to Medellín from $122

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Medellín departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
9:54 pm - 1:08 pm
CLT
-
MDE
16h 14m
1 stop
Multiple Airlines Logo
2:06 pm - 2:12 pm
MDE
-
CLT
23h 06m
1 stop
$306Multiple Airlines
Sat, Apr 25 - Sat, May 2
Spirit Airlines Logo
9:54 pm - 1:08 pm
CLT
-
MDE
16h 14m
1 stop
Spirit Airlines Logo
1:55 pm - 8:09 am
MDE
-
CLT
17h 14m
1 stop
$307Spirit Airlines
Sat, Apr 25 - Sat, May 2
Multiple Airlines Logo
9:15 am - 12:21 am
CLT
-
MDE
16h 06m
1 stop
Multiple Airlines Logo
2:17 pm - 9:10 am
MDE
-
CLT
17h 53m
1 stop
$310Multiple Airlines
Wed, Apr 8 - Tue, Apr 14
Spirit Airlines Logo
9:54 pm - 1:08 pm
CLT
-
MDE
16h 14m
1 stop
Spirit Airlines Logo
2:06 pm - 9:10 am
MDE
-
CLT
18h 04m
1 stop
$311Spirit Airlines
Sat, Apr 18 - Sat, Apr 25
Spirit Airlines Logo
9:54 pm - 1:08 pm
CLT
-
MDE
16h 14m
1 stop
Spirit Airlines Logo
1:55 pm - 8:09 am
MDE
-
CLT
17h 14m
1 stop
$313Spirit Airlines
Sat, Apr 25 - Sat, May 2
Multiple Airlines Logo
8:56 am - 1:08 pm
CLT
-
MDE
29h 12m
1 stop
Multiple Airlines Logo
2:06 pm - 2:18 pm
MDE
-
CLT
23h 12m
1 stop
$316Multiple Airlines
Thu, Apr 23 - Thu, Apr 30
American Airlines Logo
8:35 pm - 12:51 pm
GSP
-
MDE
17h 16m
1 stop
American Airlines Logo
6:00 am - 7:30 pm
MDE
-
GSP
12h 30m
1 stop
$540American Airlines
Sat, Jun 20 - Thu, Jul 16
United Airlines Logo
7:40 pm - 9:10 pm
GSP
-
MDE
26h 30m
2 stops
United Airlines Logo
9:45 am - 9:53 pm
MDE
-
GSP
11h 08m
1 stop
$545United Airlines
Mon, Aug 3 - Tue, Aug 18
American Airlines Logo
6:09 pm - 11:58 pm
GSP
-
MDE
6h 49m
1 stop
American Airlines Logo
12:25 am - 6:14 pm
MDE
-
GSP
16h 49m
1 stop
$550American Airlines
Sat, Aug 1 - Sun, Aug 16
United Airlines Logo
11:30 am - 9:10 pm
MYR
-
MDE
34h 40m
2 stops
United Airlines Logo
9:45 am - 10:42 am
MDE
-
MYR
23h 57m
2 stops
$626United Airlines
Sat, May 9 - Sat, May 16

LATAM Airlines flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best LATAM Airlines deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
LATAM Airlines
Jul 18
SAV6:00 amSavannah/Hilton Head
16h 05m
2 stops
MDE9:05 pmMedellín Jose Maria Cordova Intl
Aug 2
MDE8:25 amMedellín Jose Maria Cordova Intl
14h 28m
2 stops
SAV11:53 pmSavannah/Hilton Head
$659
LATAM Airlines
Aug 1
GSP9:00 amGreenville
15h 45m
2 stops
MDE11:45 pmMedellín Jose Maria Cordova Intl
Aug 16
MDE6:20 amMedellín Jose Maria Cordova Intl
16h 18m
2 stops
GSP11:38 pmGreenville
$681
LATAM Airlines
Apr 3
GSP8:30 amGreenville
16h 10m
2 stops
MDE11:40 pmMedellín Jose Maria Cordova Intl
Apr 20
MDE6:20 amMedellín Jose Maria Cordova Intl
16h 36m
2 stops
GSP11:56 pmGreenville
$805

Delta flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best Delta deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
Delta
Apr 9
SAV12:33 pmSavannah/Hilton Head
12h 07m
2 stops
MDE11:40 pmMedellín Jose Maria Cordova Intl
Apr 18
MDE5:45 amMedellín Jose Maria Cordova Intl
17h 14m
2 stops
SAV11:59 pmSavannah/Hilton Head
$778
Delta
Apr 8
GSP8:30 amGreenville
15h 00m
2 stops
MDE10:30 pmMedellín Jose Maria Cordova Intl
Apr 11
MDE6:20 amMedellín Jose Maria Cordova Intl
16h 34m
2 stops
GSP11:54 pmGreenville
$783
Delta
Apr 10
SAV9:01 amSavannah/Hilton Head
15h 39m
2 stops
MDE11:40 pmMedellín Jose Maria Cordova Intl
Apr 19
MDE5:45 amMedellín Jose Maria Cordova Intl
17h 14m
2 stops
SAV11:59 pmSavannah/Hilton Head
$788

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 4/25

9:54 pm-1:08 pm

1 stop16h 14m

Medellín Jose Maria Cordova Intl

Sat 5/2

2:06 pm-2:12 pm

1 stop23h 06m

$306

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 4/25

9:54 pm-1:08 pm

1 stop16h 14m

Medellín Jose Maria Cordova Intl

Sat 5/2

1:55 pm-8:09 am

1 stop17h 14m

$307

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 4/8

9:15 am-12:21 am

1 stop16h 06m

Medellín Jose Maria Cordova Intl

Tue 4/14

2:17 pm-9:10 am

1 stop17h 53m

$310

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 4/18

9:54 pm-1:08 pm

1 stop16h 14m

Medellín Jose Maria Cordova Intl

Sat 4/25

2:06 pm-9:10 am

1 stop18h 04m

$311

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 4/25

9:54 pm-1:08 pm

1 stop16h 14m

Medellín Jose Maria Cordova Intl

Sat 5/2

1:55 pm-8:09 am

1 stop17h 14m

$313

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Thu 4/23

8:56 am-1:08 pm

1 stop29h 12m

Medellín Jose Maria Cordova Intl

Thu 4/30

2:06 pm-2:18 pm

1 stop23h 12m

$316

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 6/20

8:35 pm-12:51 pm

1 stop17h 16m

Medellín Jose Maria Cordova Intl

Thu 7/16

6:00 am-7:30 pm

1 stop12h 30m

$540

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 8/3

7:40 pm-9:10 pm

2 stops26h 30m

Medellín Jose Maria Cordova Intl

Tue 8/18

9:45 am-9:53 pm

1 stop11h 08m

$545
Quickest round-trip

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 8/1

6:09 pm-11:58 pm

1 stop6h 49m

Medellín Jose Maria Cordova Intl

Sun 8/16

12:25 am-6:14 pm

1 stop16h 49m

$550

Myrtle BeachMedellín

MYR - MDE

MYRMDE

Myrtle Beach Intl

Sat 5/9

11:30 am-9:10 pm

2 stops34h 40m

Medellín Jose Maria Cordova Intl

Sat 5/16

9:45 am-10:42 am

2 stops23h 57m

$626

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Medellín from

How to get the cheapest flight ticket from South Carolina to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, September is the cheapest month to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $285. If you aren’t able to travel during the month of September, then book flights to Medellín Jose Maria Cordova Intl Airport from South Carolina during March instead. Flights to Medellín Jose Maria Cordova Intl Airport in March, while not as cheap as those in September, still average around $523.

Can stopping save me money on South Carolina to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 21% on your flight if you consider stops on a South Carolina to Medellín Jose Maria Cordova Intl Airport flight.

Cheap South Carolina to Medellín Jose Maria Cordova Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Medellín Jose Maria Cordova Intl Airport

Fastest flight time

7h 43m

Direct flights

None
The fastest flight from South Carolina to Medellín Jose Maria Cordova Intl Airport takes 7h 43m
There are no direct flights from South Carolina to Medellín Jose Maria Cordova Intl Airport. There are no popular flight routes from South Carolina to Medellín Jose Maria Cordova Intl Airport.
  • When did momondo last update prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The required travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $327Free CancellationRating
6.3
8,551 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $515Free CancellationRating
7.1
11,520 reviews
Search American Airlines flights

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Medellín?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Medellín. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Medellín with flexible booking policies on momondo?

Yes. All flights to Medellín from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Medellín?

momondo helps you find the best flight between South Carolina and Medellín by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Medellín right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Medellín flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Tue 4/28
Tue 5/5

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