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Cheap flights from South Carolina to Medellín from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Medellín departing on 9/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Medellín

Cheap round-trip flights

Spirit Airlines Logo
10:17 am - 12:25 amCLT-MDE
15h 08m1 stop
Spirit Airlines Logo
2:09 pm - 9:22 amMDE-CLT
18h 13m1 stop
$254Spirit Airlines
Find Deal
Tue, Oct 21 - Tue, Oct 28
Spirit Airlines Logo
10:46 am - 12:25 amCLT-MDE
14h 39m1 stop
Spirit Airlines Logo
1:24 am - 8:27 pmMDE-CLT
18h 03m1 stop
$263Spirit Airlines
Find Deal
Wed, Sep 10 - Sun, Sep 21
Spirit Airlines Logo
5:05 pm - 12:25 amCLT-MDE
8h 20m1 stop
Spirit Airlines Logo
2:09 pm - 9:22 amMDE-CLT
18h 13m1 stop
$272Spirit Airlines
Find Deal
Fri, Sep 12 - Fri, Sep 19
Logo
10:31 am - 12:25 amCHS-MDE
14h 54m1 stop
Logo
2:00 pm - 8:37 amMDE-CHS
17h 37m1 stop
$386
Find Deal
Fri, Sep 19 - Mon, Sep 29
Logo
2:50 pm - 1:04 pmGSP-MDE
23h 14m1 stop
Logo
6:40 am - 8:28 pmMDE-GSP
12h 48m2 stops
$470
Find Deal
Mon, Aug 25 - Sun, Aug 31
American Airlines Logo
6:00 am - 8:15 pmGSP-MDE
15h 15m1 stop
American Airlines Logo
1:35 pm - 11:21 pmMDE-GSP
8h 46m1 stop
$506American Airlines
Find Deal
Mon, Oct 20 - Tue, Oct 28
American Airlines Logo
5:00 am - 8:15 pmGSP-MDE
16h 15m2 stops
American Airlines Logo
6:00 am - 8:43 pmMDE-GSP
13h 43m2 stops
$510American Airlines
Find Deal
Mon, Oct 20 - Tue, Oct 28
United Airlines Logo
7:00 am - 9:10 pmGSP-MDE
15h 10m1 stop
United Airlines Logo
9:45 am - 9:59 pmMDE-GSP
11h 14m1 stop
$516United Airlines
Find Deal
Sat, Oct 18 - Mon, Oct 27
United Airlines Logo
9:35 am - 9:10 pmGSP-MDE
12h 35m2 stops
United Airlines Logo
9:45 am - 9:59 pmMDE-GSP
11h 14m1 stop
$520United Airlines
Find Deal
Sat, Oct 18 - Mon, Oct 27
JetBlue Logo
11:18 am - 1:55 pmSAV-MDE
27h 37m2 stops
JetBlue Logo
1:30 pm - 3:15 pmMDE-SAV
24h 45m2 stops
$571JetBlue
Find Deal
Thu, Sep 4 - Sun, Sep 7

American Airlines flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best American Airlines deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
American Airlines
Oct 20
GSP6:00 amGreenville
15h 15m
1 stop
MDE8:15 pmMedellín Jose Maria Cordova Intl
Oct 28
MDE1:35 pmMedellín Jose Maria Cordova Intl
8h 46m
1 stop
GSP11:21 pmGreenville
$506
Find similar
American Airlines
Oct 20
GSP5:00 amGreenville
16h 15m
2 stops
MDE8:15 pmMedellín Jose Maria Cordova Intl
Oct 28
MDE6:00 amMedellín Jose Maria Cordova Intl
13h 43m
2 stops
GSP8:43 pmGreenville
$510
Find similar
American Airlines
Nov 12
CHS9:27 amCharleston
14h 12m
1 stop
MDE11:39 pmMedellín Jose Maria Cordova Intl
Nov 24
MDE7:00 amMedellín Jose Maria Cordova Intl
12h 19m
1 stop
CHS7:19 pmCharleston
$523
Find similar

Spirit Airlines flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best Spirit Airlines deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
Spirit Airlines
Oct 21
CLT10:17 amCharlotte Douglas
15h 08m
1 stop
MDE12:25 amMedellín Jose Maria Cordova Intl
Oct 28
MDE2:09 pmMedellín Jose Maria Cordova Intl
18h 13m
1 stop
CLT9:22 amCharlotte Douglas
$254
Find similar
Spirit Airlines
Sep 10
CLT10:46 amCharlotte Douglas
14h 39m
1 stop
MDE12:25 amMedellín Jose Maria Cordova Intl
Sep 21
MDE1:24 amMedellín Jose Maria Cordova Intl
18h 03m
1 stop
CLT8:27 pmCharlotte Douglas
$263
Find similar
Spirit Airlines
Sep 12
CLT5:05 pmCharlotte Douglas
8h 20m
1 stop
MDE12:25 amMedellín Jose Maria Cordova Intl
Sep 19
MDE2:09 pmMedellín Jose Maria Cordova Intl
18h 13m
1 stop
CLT9:22 amCharlotte Douglas
$272
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 10/21

10:17 am-12:25 am

1 stop15h 08m

Medellín Jose Maria Cordova Intl

Tue 10/28

2:09 pm-9:22 am

1 stop18h 13m

$254

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 9/10

10:46 am-12:25 am

1 stop14h 39m

Medellín Jose Maria Cordova Intl

Sun 9/21

1:24 am-8:27 pm

1 stop18h 03m

$263

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 9/12

5:05 pm-12:25 am

1 stop8h 20m

Medellín Jose Maria Cordova Intl

Fri 9/19

2:09 pm-9:22 am

1 stop18h 13m

$272

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Fri 9/19

10:31 am-12:25 am

1 stop14h 54m

Medellín Jose Maria Cordova Intl

Mon 9/29

2:00 pm-8:37 am

1 stop17h 37m

$386

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 8/25

2:50 pm-1:04 pm

1 stop23h 14m

Medellín Jose Maria Cordova Intl

Sun 8/31

6:40 am-8:28 pm

2 stops12h 48m

$470

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/20

6:00 am-8:15 pm

1 stop15h 15m

Medellín Jose Maria Cordova Intl

Tue 10/28

1:35 pm-11:21 pm

1 stop8h 46m

$506

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/20

5:00 am-8:15 pm

2 stops16h 15m

Medellín Jose Maria Cordova Intl

Tue 10/28

6:00 am-8:43 pm

2 stops13h 43m

$510

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 10/18

7:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

Mon 10/27

9:45 am-9:59 pm

1 stop11h 14m

$516

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 10/18

9:35 am-9:10 pm

2 stops12h 35m

Medellín Jose Maria Cordova Intl

Mon 10/27

9:45 am-9:59 pm

1 stop11h 14m

$520

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Thu 9/4

11:18 am-1:55 pm

2 stops27h 37m

Medellín Jose Maria Cordova Intl

Sun 9/7

1:30 pm-3:15 pm

2 stops24h 45m

$571

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, January is the cheapest month to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $303. If you aren’t able to travel during the month of January, then book flights to Medellín Jose Maria Cordova Intl Airport from South Carolina during March instead. Flights to Medellín Jose Maria Cordova Intl Airport in March, while not as cheap as those in January, still average around $539.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from South Carolina to Medellín Jose Maria Cordova Intl Airport is on a Wednesday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Wednesday will often find tickets for as low as $323. On the other hand, Thursday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $628.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest South Carolina to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times at noon. Our users have found flights to Medellín Jose Maria Cordova Intl Airport at noon for as low as $323. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the evening when prices are around $941.

Can stopping save me money on South Carolina to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 10% on your flight if you consider stops on a South Carolina to Medellín Jose Maria Cordova Intl Airport flight.

Cheap South Carolina to Medellín Jose Maria Cordova Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Medellín Jose Maria Cordova Intl Airport

Best Price Found

$110

Fastest flight time

6h 29m

Direct flights

None
The best one-way flight to Medellín Jose Maria Cordova Intl Airport from South Carolina in the past 72 hours is $110. The best round-trip flight deal from South Carolina to Medellín Jose Maria Cordova Intl Airport found on momondo in the last 72 hours is $254.
The fastest flight from South Carolina to Medellín Jose Maria Cordova Intl Airport takes 6h 29m
There are no direct flights from South Carolina to Medellín Jose Maria Cordova Intl Airport. Popular non-direct routes for this connection are Savannah/Hilton Head Airport - Medellín Jose Maria Cordova Intl Airport, Charlotte Douglas Airport - Medellín Jose Maria Cordova Intl Airport and Charleston Airport - Medellín Jose Maria Cordova Intl Airport.
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  • When did momondo last update prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The required travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $333Free CancellationRating
6.3
8,048 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $471Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $565Free CancellationRating
7.5
1,822 reviews
Search LATAM Airlines flights

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Medellín?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Medellín. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Medellín with flexible booking policies on momondo?

Yes. All flights to Medellín from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Medellín?

momondo helps you find the best flight between South Carolina and Medellín by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Medellín right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Medellín flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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