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Cheap flights from South Carolina to Medellín from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Medellín departing on 9/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Medellín

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:00 am - 9:10 pmCHS  Charleston-MDE Medellín Jose Maria Cordova Intl
15h 10m1 stop Houston George Bush Intcntl
United Airlines Logo
9:45 am - 10:21 pmMDE  Medellín Jose Maria Cordova Intl-CHS Charleston
11h 36m1 stop Houston George Bush Intcntl
$379United Airlines
Sat, Oct 17 - Sat, Oct 24
United Airlines Logo
7:00 am - 9:10 pmCHS  Charleston-MDE Medellín Jose Maria Cordova Intl
15h 10m1 stop Houston George Bush Intcntl
United Airlines Logo
9:45 am - 9:59 pmMDE  Medellín Jose Maria Cordova Intl-CHS Charleston
11h 14m1 stop Houston George Bush Intcntl
$379United Airlines
Sat, Oct 17 - Sun, Oct 25
United Airlines Logo
6:50 pm - 9:10 pmCHS  Charleston-MDE Medellín Jose Maria Cordova Intl
27h 20m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
United Airlines Logo
9:45 am - 10:06 amMDE  Medellín Jose Maria Cordova Intl-CHS Charleston
23h 21m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl
$384United Airlines
Sat, Oct 17 - Sat, Oct 24
American Airlines Logo
7:26 pm - 2:12 pmCHS  Charleston-MDE Medellín Jose Maria Cordova Intl
18h 46m2 stops Charlotte Douglas Miami
American Airlines Logo
7:30 am - 11:59 pmMDE  Medellín Jose Maria Cordova Intl-CHS Charleston
16h 29m1 stop Miami
$474American Airlines
Wed, Nov 11 - Sun, Nov 15
American Airlines Logo
7:41 pm - 12:48 pmCHS  Charleston-MDE Medellín Jose Maria Cordova Intl
18h 07m2 stops Charlotte Douglas Miami
American Airlines Logo
6:00 am - 10:57 pmMDE  Medellín Jose Maria Cordova Intl-CHS Charleston
15h 57m2 stops Miami Charlotte Douglas
$479American Airlines
Fri, Sep 25 - Tue, Oct 6
American Airlines Logo
1:17 pm - 9:15 pmCLT  Charlotte Douglas-MDE Medellín Jose Maria Cordova Intl
7h 58m1 stop Miami
American Airlines Logo
7:30 am - 11:59 pmMDE  Medellín Jose Maria Cordova Intl-CLT Charlotte Douglas
16h 29m1 stop Miami
$549American Airlines
Sat, Nov 14 - Sat, Dec 5
JetBlue Logo
9:00 am - 2:30 pmCLT  Charlotte Douglas-MDE Medellín Jose Maria Cordova Intl
6h 30m1 stop Fort Lauderdale
JetBlue Logo
1:30 pm - 11:05 pmMDE  Medellín Jose Maria Cordova Intl-CLT Charlotte Douglas
8h 35m1 stop Fort Lauderdale
$690JetBlue
Mon, Oct 19 - Fri, Oct 23
GOL Logo
6:00 pm - 8:15 pmCLT  Charlotte Douglas-MDE Medellín Jose Maria Cordova Intl
27h 15m1 stop Miami
GOL Logo
6:00 am - 10:20 amMDE  Medellín Jose Maria Cordova Intl-CLT Charlotte Douglas
27h 20m1 stop Miami
$898GOL
Thu, Sep 3 - Tue, Sep 8
GOL Logo
10:44 pm - 12:48 pmCLT  Charlotte Douglas-MDE Medellín Jose Maria Cordova Intl
15h 04m1 stop Miami
GOL Logo
1:50 pm - 6:27 amMDE  Medellín Jose Maria Cordova Intl-CLT Charlotte Douglas
15h 37m2 stops Miami Washington, D.C. Reagan-National
$943GOL
Fri, Oct 9 - Sun, Oct 11
JetBlue Logo
9:00 am - 3:30 pmCLT  Charlotte Douglas-MDE Medellín Jose Maria Cordova Intl
6h 30m1 stop Fort Lauderdale
JetBlue Logo
2:30 pm - 11:00 pmMDE  Medellín Jose Maria Cordova Intl-CLT Charlotte Douglas
8h 30m1 stop Fort Lauderdale
$989JetBlue
Tue, Nov 17 - Tue, Nov 24

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American Airlines flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best American Airlines deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
American Airlines
Nov 11
CHS7:26 pmCharleston
18h 46m
2 stops
MDE2:12 pmMedellín Jose Maria Cordova Intl
Nov 15
MDE7:30 amMedellín Jose Maria Cordova Intl
16h 29m
1 stop
CHS11:59 pmCharleston
$474
American Airlines
Sep 24
CHS6:00 amCharleston
15h 15m
2 stops
MDE8:15 pmMedellín Jose Maria Cordova Intl
Oct 6
MDE1:50 pmMedellín Jose Maria Cordova Intl
9h 09m
1 stop
CHS11:59 pmCharleston
$479
American Airlines
Nov 11
CHS7:00 amCharleston
14h 15m
1 stop
MDE9:15 pmMedellín Jose Maria Cordova Intl
Nov 15
MDE7:30 amMedellín Jose Maria Cordova Intl
16h 29m
1 stop
CHS11:59 pmCharleston
$534

Avianca flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best Avianca deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
Avianca
Sep 10
GSP6:10 pmGreenville
22h 50m
2 stops
MDE4:00 pmMedellín Jose Maria Cordova Intl
Sep 14
MDE9:30 amMedellín Jose Maria Cordova Intl
23h 05m
2 stops
GSP9:35 amGreenville
$720
Avianca
Aug 22
CLT10:25 amCharlotte Douglas
20h 55m
2 stops
MDE6:20 amMedellín Jose Maria Cordova Intl
Aug 25
MDE2:10 pmMedellín Jose Maria Cordova Intl
27h 46m
2 stops
CLT6:56 pmCharlotte Douglas
$827
Avianca
Aug 22
CLT10:25 amCharlotte Douglas
13h 00m
2 stops
MDE10:25 pmMedellín Jose Maria Cordova Intl
Aug 25
MDE2:10 pmMedellín Jose Maria Cordova Intl
27h 46m
2 stops
CLT6:56 pmCharlotte Douglas
$854

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonMedellín

CHS Charleston - MDE Medellín Jose Maria Cordova Intl

CHSMDE

Charleston

Sat 10/17

7:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

Sat 10/24

9:45 am-10:21 pm

1 stop11h 36m

$379

CharlestonMedellín

CHS Charleston - MDE Medellín Jose Maria Cordova Intl

CHSMDE

Charleston

Sat 10/17

7:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

Sun 10/25

9:45 am-9:59 pm

1 stop11h 14m

$379

CharlestonMedellín

CHS Charleston - MDE Medellín Jose Maria Cordova Intl

CHSMDE

Charleston

Sat 10/17

6:50 pm-9:10 pm

2 stops27h 20m

Medellín Jose Maria Cordova Intl

Sat 10/24

9:45 am-10:06 am

2 stops23h 21m

$384

CharlestonMedellín

CHS Charleston - MDE Medellín Jose Maria Cordova Intl

CHSMDE

Charleston

Wed 11/11

7:26 pm-2:12 pm

2 stops18h 46m

Medellín Jose Maria Cordova Intl

Sun 11/15

7:30 am-11:59 pm

1 stop16h 29m

$474

CharlestonMedellín

CHS Charleston - MDE Medellín Jose Maria Cordova Intl

CHSMDE

Charleston

Fri 9/25

7:41 pm-12:48 pm

2 stops18h 07m

Medellín Jose Maria Cordova Intl

Tue 10/6

6:00 am-10:57 pm

2 stops15h 57m

$479

CharlotteMedellín

CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl

CLTMDE

Charlotte Douglas

Sat 11/14

1:17 pm-9:15 pm

1 stop7h 58m

Medellín Jose Maria Cordova Intl

Sat 12/5

7:30 am-11:59 pm

1 stop16h 29m

$549

CharlotteMedellín

CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl

CLTMDE

Charlotte Douglas

Mon 10/19

9:00 am-2:30 pm

1 stop6h 30m

Medellín Jose Maria Cordova Intl

Fri 10/23

1:30 pm-11:05 pm

1 stop8h 35m

$690

CharlotteMedellín

CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl

CLTMDE

Charlotte Douglas

Thu 9/3

6:00 pm-8:15 pm

1 stop27h 15m

Medellín Jose Maria Cordova Intl

Tue 9/8

6:00 am-10:20 am

1 stop27h 20m

$898

CharlotteMedellín

CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl

CLTMDE

Charlotte Douglas

Fri 10/9

10:44 pm-12:48 pm

1 stop15h 04m

Medellín Jose Maria Cordova Intl

Sun 10/11

1:50 pm-6:27 am

2 stops15h 37m

$943
Quickest round-trip

CharlotteMedellín

CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl

CLTMDE

Charlotte Douglas

Tue 11/17

9:00 am-3:30 pm

1 stop6h 30m

Medellín Jose Maria Cordova Intl

Tue 11/24

2:30 pm-11:00 pm

1 stop8h 30m

$989

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Medellín from

How to get the cheapest flight ticket from South Carolina to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, March is the cheapest month to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $523. If you aren’t able to travel during the month of March, then book flights to Medellín Jose Maria Cordova Intl Airport from South Carolina during February instead. Flights to Medellín Jose Maria Cordova Intl Airport in February, while not as cheap as those in March, still average around $663.

Can stopping save me money on South Carolina to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 4% on your flight if you consider stops on a South Carolina to Medellín Jose Maria Cordova Intl Airport flight.

Cheap South Carolina to Medellín Jose Maria Cordova Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Medellín Jose Maria Cordova Intl Airport

Fastest flight time

6h 30m

Direct flights

None
The fastest flight from South Carolina to Medellín Jose Maria Cordova Intl Airport takes 6h 30m
There are no direct flights from South Carolina to Medellín Jose Maria Cordova Intl Airport. There are no popular flight routes from South Carolina to Medellín Jose Maria Cordova Intl Airport.
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Frequently asked questions about flying from South Carolina to Medellín Jose Maria Cordova Intl Airport

  • When did momondo last update prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The required travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $515Free CancellationRating
7.1
11,923 reviews
Search American Airlines flights

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Medellín?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Medellín. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Medellín with flexible booking policies on momondo?

Yes. All flights to Medellín from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Medellín?

momondo helps you find the best flight between South Carolina and Medellín by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Medellín right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Medellín flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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