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Cheap flights from South Carolina to Medellín from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Medellín departing on 2/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Medellín

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
Spirit Airlines Logo
3:15 pm - 12:40 am
MDE
-
CLT
9h 25m1 stop
$257Spirit Airlines
Fri, Feb 6 - Wed, Feb 11
Spirit Airlines Logo
6:00 am - 2:15 pm
CLT
-
MDE
8h 15m1 stop
Spirit Airlines Logo
3:15 pm - 12:40 am
MDE
-
CLT
9h 25m1 stop
$258Spirit Airlines
Sat, Jan 31 - Sat, Feb 7
Spirit Airlines Logo
7:00 am - 2:13 pm
CLT
-
MDE
7h 13m1 stop
Spirit Airlines Logo
3:15 pm - 8:26 am
MDE
-
CLT
17h 11m1 stop
$274Spirit Airlines
Wed, Feb 18 - Sun, Feb 22
Multiple Airlines Logo
11:00 am - 2:13 pm
CLT
-
MDE
27h 13m1 stop
Multiple Airlines Logo
3:15 pm - 11:54 pm
MDE
-
CLT
8h 39m1 stop
$298Multiple Airlines
Thu, Feb 19 - Tue, Feb 24
Multiple Airlines Logo
9:43 pm - 10:55 am
CLT
-
MDE
13h 12m1 stop
Multiple Airlines Logo
2:50 pm - 8:03 am
MDE
-
CLT
17h 13m1 stop
$313Multiple Airlines
Mon, Jan 5 - Thu, Jan 15
JetBlue Logo
2:00 pm - 2:45 pm
CHS
-
MDE
24h 45m1 stop
JetBlue Logo
1:25 pm - 11:43 am
MDE
-
CHS
21h 18m1 stop
$474JetBlue
Wed, Mar 4 - Thu, Mar 12
American Airlines Logo
7:29 pm - 2:06 pm
GSP
-
MDE
18h 37m1 stop
American Airlines Logo
7:00 am - 6:42 pm
MDE
-
GSP
10h 42m1 stop
$516American Airlines
Fri, Mar 6 - Tue, Mar 24
American Airlines Logo
7:29 pm - 2:06 pm
GSP
-
MDE
18h 37m1 stop
American Airlines Logo
7:00 am - 6:32 pm
MDE
-
GSP
10h 32m2 stops
$520American Airlines
Fri, Mar 6 - Tue, Mar 24
United Airlines Logo
5:45 am - 9:10 pm
SAV
-
MDE
16h 25m2 stops
United Airlines Logo
9:45 am - 12:11 am
MDE
-
SAV
13h 26m2 stops
$532United Airlines
Thu, May 7 - Wed, May 20
United Airlines Logo
6:30 pm - 9:10 pm
SAV
-
MDE
27h 40m2 stops
United Airlines Logo
9:45 am - 3:36 pm
MDE
-
SAV
28h 51m2 stops
$542United Airlines
Wed, May 6 - Sat, May 16

Spirit Airlines flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best Spirit Airlines deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
Spirit Airlines
Feb 6
CLT6:00 amCharlotte Douglas
8h 15m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Feb 11
MDE3:15 pmMedellín Jose Maria Cordova Intl
9h 25m
1 stop
CLT12:40 amCharlotte Douglas
$257
Find similar
Spirit Airlines
Jan 31
CLT6:00 amCharlotte Douglas
8h 15m
1 stop
MDE2:15 pmMedellín Jose Maria Cordova Intl
Feb 7
MDE3:15 pmMedellín Jose Maria Cordova Intl
9h 25m
1 stop
CLT12:40 amCharlotte Douglas
$258
Find similar
Spirit Airlines
Feb 18
CLT7:00 amCharlotte Douglas
7h 13m
1 stop
MDE2:13 pmMedellín Jose Maria Cordova Intl
Feb 22
MDE3:15 pmMedellín Jose Maria Cordova Intl
17h 11m
1 stop
CLT8:26 amCharlotte Douglas
$274
Find similar

United Airlines flights from South Carolina to Medellín Jose Maria Cordova Intl Airport

Our best United Airlines deals on South Carolina to Medellín Jose Maria Cordova Intl Airport flight tickets
United Airlines
May 7
SAV5:45 amSavannah/Hilton Head
16h 25m
2 stops
MDE9:10 pmMedellín Jose Maria Cordova Intl
May 20
MDE9:45 amMedellín Jose Maria Cordova Intl
13h 26m
2 stops
SAV12:11 amSavannah/Hilton Head
$532
Find similar
United Airlines
May 6
SAV6:30 pmSavannah/Hilton Head
27h 40m
2 stops
MDE9:10 pmMedellín Jose Maria Cordova Intl
May 16
MDE9:45 amMedellín Jose Maria Cordova Intl
28h 51m
2 stops
SAV3:36 pmSavannah/Hilton Head
$542
Find similar
United Airlines
Feb 12
GSP10:40 amGreenville
35h 25m
2 stops
MDE10:05 pmMedellín Jose Maria Cordova Intl
Mar 2
MDE10:45 amMedellín Jose Maria Cordova Intl
23h 16m
2 stops
GSP10:01 amGreenville
$549
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South Carolina to Medellín Jose Maria Cordova Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Fri 2/6

6:00 am-2:15 pm

1 stop8h 15m

Medellín Jose Maria Cordova Intl

Wed 2/11

3:15 pm-12:40 am

1 stop9h 25m

$257

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 1/31

6:00 am-2:15 pm

1 stop8h 15m

Medellín Jose Maria Cordova Intl

Sat 2/7

3:15 pm-12:40 am

1 stop9h 25m

$258

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 2/18

7:00 am-2:13 pm

1 stop7h 13m

Medellín Jose Maria Cordova Intl

Sun 2/22

3:15 pm-8:26 am

1 stop17h 11m

$274

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Thu 2/19

11:00 am-2:13 pm

1 stop27h 13m

Medellín Jose Maria Cordova Intl

Tue 2/24

3:15 pm-11:54 pm

1 stop8h 39m

$298

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 1/5

9:43 pm-10:55 am

1 stop13h 12m

Medellín Jose Maria Cordova Intl

Thu 1/15

2:50 pm-8:03 am

1 stop17h 13m

$313

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 3/4

2:00 pm-2:45 pm

1 stop24h 45m

Medellín Jose Maria Cordova Intl

Thu 3/12

1:25 pm-11:43 am

1 stop21h 18m

$474

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 3/6

7:29 pm-2:06 pm

1 stop18h 37m

Medellín Jose Maria Cordova Intl

Tue 3/24

7:00 am-6:42 pm

1 stop10h 42m

$516

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 3/6

7:29 pm-2:06 pm

1 stop18h 37m

Medellín Jose Maria Cordova Intl

Tue 3/24

7:00 am-6:32 pm

2 stops10h 32m

$520

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Thu 5/7

5:45 am-9:10 pm

2 stops16h 25m

Medellín Jose Maria Cordova Intl

Wed 5/20

9:45 am-12:11 am

2 stops13h 26m

$532

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

Wed 5/6

6:30 pm-9:10 pm

2 stops27h 40m

Medellín Jose Maria Cordova Intl

Sat 5/16

9:45 am-3:36 pm

2 stops28h 51m

$542

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from South Carolina to Medellín Jose Maria Cordova Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Medellín Jose Maria Cordova Intl Airport?

In general, September is the cheapest month to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $399. If you aren’t able to travel during the month of September, then book flights to Medellín Jose Maria Cordova Intl Airport from South Carolina during April instead. Flights to Medellín Jose Maria Cordova Intl Airport in April, while not as cheap as those in September, still average around $531.

What is the cheapest day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

The cheapest day to depart from South Carolina to Medellín Jose Maria Cordova Intl Airport is on a Wednesday. Travelers who choose to depart for Medellín Jose Maria Cordova Intl Airport on a Wednesday will often find tickets for as low as $323. On the other hand, Thursday is the most expensive day to depart from South Carolina because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $628.

What is the cheapest time of day to depart on your flight to Medellín Jose Maria Cordova Intl Airport?

Our data shows that the cheapest South Carolina to Medellín Jose Maria Cordova Intl Airport flights are usually those with departure times at noon. Our users have found flights to Medellín Jose Maria Cordova Intl Airport at noon for as low as $323. In contrast, the most expensive time of day to depart to Medellín Jose Maria Cordova Intl Airport is in the evening when prices are around $941.

Can stopping save me money on South Carolina to Medellín Jose Maria Cordova Intl Airport flights?

You could potentially save up to 70% on your flight if you consider stops on a South Carolina to Medellín Jose Maria Cordova Intl Airport flight.

Cheap South Carolina to Medellín Jose Maria Cordova Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Medellín Jose Maria Cordova Intl Airport

Fastest flight time

7h 13m

Direct flights

None
The fastest flight from South Carolina to Medellín Jose Maria Cordova Intl Airport takes 7h 13m
There are no direct flights from South Carolina to Medellín Jose Maria Cordova Intl Airport. There are no popular flight routes from South Carolina to Medellín Jose Maria Cordova Intl Airport.
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  • When did momondo last update prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    Prices for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from South Carolina to Medellín Jose Maria Cordova Intl Airport?

  • How old do you have to be to fly from South Carolina to Medellín Jose Maria Cordova Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Medellín Jose Maria Cordova Intl Airport.

  • What documentation or ID do you need to fly to Medellín Jose Maria Cordova Intl Airport?

    The required travel and health documents for your Medellín Jose Maria Cordova Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Medellín Jose Maria Cordova Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Medellín Jose Maria Cordova Intl Airport

Compare and see reviews for airlines that fly from South Carolina to Medellín Jose Maria Cordova Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $327Free CancellationRating
6.3
8,190 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $471Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights

Traveling to a place near Medellín?

Book flights to Medellín if you plan to visit one of these locations
Guatapé
Rionegro

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Medellín?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Medellín. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Medellín with flexible booking policies on momondo?

Yes. All flights to Medellín from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Medellín?

momondo helps you find the best flight between South Carolina and Medellín by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from South Carolina to Medellín right now. Can momondo alert me if prices change?

Yes. momondo can track prices for South Carolina to Medellín flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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