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Cheap flights from South Carolina to Brussels from $379

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Brussels departing on 10/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
Aer Lingus Logo
1:02 pm - 9:40 am
CLT
-
BRU
14h 38m
2 stops
Aer Lingus Logo
10:20 am - 9:43 pm
BRU
-
CLT
17h 23m
2 stops
$734Aer Lingus
Sun, Aug 16 - Sun, Aug 23
United Airlines Logo
3:00 pm - 7:15 am
CLT
-
BRU
10h 15m
1 stop
United Airlines Logo
10:00 am - 6:48 pm
BRU
-
CLT
38h 48m
3 stops
$737United Airlines
Mon, Nov 23 - Tue, Dec 1
Lufthansa Logo
6:50 pm - 5:15 pm
CLT
-
BRU
16h 25m
1 stop
Lufthansa Logo
6:45 am - 4:55 pm
BRU
-
CLT
16h 10m
1 stop
$746Lufthansa
Mon, Nov 23 - Tue, Dec 1
United Airlines Logo
10:40 am - 8:55 am
CLT
-
BRU
16h 15m
1 stop
United Airlines Logo
2:25 pm - 6:48 pm
BRU
-
CLT
34h 23m
2 stops
$755United Airlines
Tue, Dec 1 - Wed, Dec 2
Multiple Airlines Logo
5:10 pm - 8:00 pm
CLT
-
BRU
20h 50m
2 stops
Multiple Airlines Logo
6:45 am - 4:55 pm
BRU
-
CLT
16h 10m
1 stop
$766Multiple Airlines
Thu, Nov 19 - Fri, Nov 27
SWISS Logo
6:50 pm - 9:30 pm
CLT
-
BRU
20h 40m
2 stops
SWISS Logo
6:40 am - 9:33 pm
BRU
-
CLT
20h 53m
2 stops
$767SWISS
Thu, Nov 19 - Fri, Nov 27
Lufthansa Logo
6:50 pm - 4:15 pm
CLT
-
BRU
15h 25m
1 stop
Lufthansa Logo
9:35 am - 4:55 pm
BRU
-
CLT
13h 20m
1 stop
$768Lufthansa
Thu, Nov 19 - Fri, Nov 27
United Airlines Logo
6:04 pm - 8:55 am
MYR
-
BRU
32h 51m
2 stops
United Airlines Logo
11:15 am - 5:23 pm
BRU
-
MYR
12h 08m
1 stop
$768United Airlines
Sun, Nov 15 - Thu, Nov 19
American Airlines Logo
8:15 pm - 4:20 pm
CLT
-
BRU
14h 05m
1 stop
American Airlines Logo
7:00 am - 4:10 pm
BRU
-
CLT
15h 10m
1 stop
$770American Airlines
Wed, Nov 18 - Sun, Nov 22
Multiple Airlines Logo
6:00 am - 7:15 am
CLT
-
BRU
19h 15m
1 stop
Multiple Airlines Logo
6:45 am - 4:55 pm
BRU
-
CLT
16h 10m
1 stop
$775Multiple Airlines
Thu, Nov 19 - Fri, Nov 27

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Aer Lingus flights from South Carolina to Brussels Bruxelles-National Airport

Our best Aer Lingus deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
Aer Lingus
Aug 4
CLT1:01 pmCharlotte Douglas
14h 39m
2 stops
BRU9:40 amBrussels Bruxelles-National
Aug 18
BRU10:20 amBrussels Bruxelles-National
16h 20m
2 stops
CLT8:40 pmCharlotte Douglas
$532
Aer Lingus
Aug 16
CLT1:02 pmCharlotte Douglas
14h 38m
2 stops
BRU9:40 amBrussels Bruxelles-National
Aug 23
BRU10:20 amBrussels Bruxelles-National
17h 23m
2 stops
CLT9:43 pmCharlotte Douglas
$734
Aer Lingus
Aug 5
CLT1:02 pmCharlotte Douglas
14h 38m
2 stops
BRU9:40 amBrussels Bruxelles-National
Aug 13
BRU10:20 amBrussels Bruxelles-National
16h 20m
2 stops
CLT8:40 pmCharlotte Douglas
$822

United Airlines flights from South Carolina to Brussels Bruxelles-National Airport

Our best United Airlines deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
United Airlines
Nov 2
CAE12:21 pmColumbia Metropolitan
18h 54m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Nov 6
BRU11:55 amBrussels Bruxelles-National
13h 06m
1 stop
CAE7:01 pmColumbia Metropolitan
$768
United Airlines
Jan 10
CAE11:18 amColumbia Metropolitan
19h 57m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Jan 20
BRU10:00 amBrussels Bruxelles-National
36h 45m
2 stops
CAE4:45 pmColumbia Metropolitan
$771
United Airlines
Nov 2
CAE10:30 amColumbia Metropolitan
20h 45m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Nov 6
BRU10:00 amBrussels Bruxelles-National
29h 47m
2 stops
CAE9:47 amColumbia Metropolitan
$772

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 19, 2026.
Use the filters below to find and compare flights from South Carolina to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 8/16

1:02 pm-9:40 am

2 stops14h 38m

Brussels Bruxelles-National

Sun 8/23

10:20 am-9:43 pm

2 stops17h 23m

$734

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Mon 11/23

3:00 pm-7:15 am

1 stop10h 15m

Brussels Bruxelles-National

Tue 12/1

10:00 am-6:48 pm

3 stops38h 48m

$737

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Mon 11/23

6:50 pm-5:15 pm

1 stop16h 25m

Brussels Bruxelles-National

Tue 12/1

6:45 am-4:55 pm

1 stop16h 10m

$746

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 12/1

10:40 am-8:55 am

1 stop16h 15m

Brussels Bruxelles-National

Wed 12/2

2:25 pm-6:48 pm

2 stops34h 23m

$755

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Thu 11/19

5:10 pm-8:00 pm

2 stops20h 50m

Brussels Bruxelles-National

Fri 11/27

6:45 am-4:55 pm

1 stop16h 10m

$766

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Thu 11/19

6:50 pm-9:30 pm

2 stops20h 40m

Brussels Bruxelles-National

Fri 11/27

6:40 am-9:33 pm

2 stops20h 53m

$767
Quickest round-trip

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Thu 11/19

6:50 pm-4:15 pm

1 stop15h 25m

Brussels Bruxelles-National

Fri 11/27

9:35 am-4:55 pm

1 stop13h 20m

$768

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Sun 11/15

6:04 pm-8:55 am

2 stops32h 51m

Brussels Bruxelles-National

Thu 11/19

11:15 am-5:23 pm

1 stop12h 08m

$768

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 11/18

8:15 pm-4:20 pm

1 stop14h 05m

Brussels Bruxelles-National

Sun 11/22

7:00 am-4:10 pm

1 stop15h 10m

$770

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Thu 11/19

6:00 am-7:15 am

1 stop19h 15m

Brussels Bruxelles-National

Fri 11/27

6:45 am-4:55 pm

1 stop16h 10m

$775

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from South Carolina to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Brussels Bruxelles-National Airport flights?

You could potentially save up to 43% on your flight if you consider stops on a South Carolina to Brussels Bruxelles-National Airport flight.

Cheap South Carolina to Brussels Bruxelles-National Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Brussels Bruxelles-National Airport

Fastest flight time

10h 15m

Direct flights

None
The fastest flight from South Carolina to Brussels Bruxelles-National Airport takes 10h 15m
There are no direct flights from South Carolina to Brussels Bruxelles-National Airport. There are no popular flight routes from South Carolina to Brussels Bruxelles-National Airport.
Search flight deals

Frequently asked questions about flying from South Carolina to Brussels Bruxelles-National Airport

  • When did momondo last update prices for flights from South Carolina to Brussels Bruxelles-National Airport?

    Prices for flights from South Carolina to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from South Carolina to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from South Carolina to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $626Free CancellationRating
7.4
10,007 reviews
Search United Airlines flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Bruges
Ghent
Leuven
Charleroi
Mons
Zaventem
Dinant
Durbuy
Hasselt
Genk
Waterloo
Aalst
Namur
Knokke-Heist
Spa
Mechelen
Francorchamps
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Brussels?

Finding the right flight to Brussels from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Brussels quick and easy, saving you time and money.

Can I find flights from South Carolina to Brussels with flexible booking policies on momondo?

All flight searches from South Carolina to Brussels on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Brussels?

momondo provides multiple filters to help you find the best flight to Brussels from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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