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Cheap flights from South Carolina to Brussels from $261

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Brussels departing on 10/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Brussels

Cheap round-trip flights

Scandinavian Airlines Logo
1:22 pm - 2:30 pmCLT-BRU
19h 08m2 stops
Scandinavian Airlines Logo
8:30 pm - 11:50 pmBRU-CLT
33h 20m2 stops
$526Scandinavian Airlines
Find Deal
Wed, Nov 19 - Sun, Nov 23
Scandinavian Airlines Logo
10:02 am - 7:50 pmCLT-BRU
27h 48m2 stops
Scandinavian Airlines Logo
10:20 am - 9:26 pmBRU-CLT
17h 06m2 stops
$527Scandinavian Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Air Canada Logo
5:05 pm - 1:15 pmCLT-BRU
14h 10m2 stops
Air Canada Logo
10:00 am - 8:57 pmBRU-CLT
16h 57m2 stops
$559Air Canada
Find Deal
Sun, Nov 16 - Tue, Dec 2
United Airlines Logo
2:30 pm - 8:05 amCLT-BRU
12h 35m1 stop
United Airlines Logo
10:00 am - 12:48 pmBRU-CLT
31h 48m2 stops
$574United Airlines
Find Deal
Tue, Mar 10 - Wed, Mar 18
Multiple Airlines Logo
5:05 pm - 1:15 pmCLT-BRU
14h 10m2 stops
Multiple Airlines Logo
9:35 am - 4:55 pmBRU-CLT
13h 20m1 stop
$586Multiple Airlines
Find Deal
Sun, Nov 16 - Tue, Dec 2
KLM Logo
1:22 pm - 9:00 amCLT-BRU
13h 38m1 stop
KLM Logo
11:00 am - 6:05 pmBRU-CLT
13h 05m1 stop
$596KLM
Find Deal
Sun, Nov 16 - Tue, Dec 2
United Airlines Logo
2:20 pm - 8:05 amCLT-BRU
11h 45m1 stop
United Airlines Logo
11:55 am - 6:59 pmBRU-CLT
13h 04m1 stop
$597United Airlines
Find Deal
Tue, Jan 13 - Wed, Jan 21
Multiple Airlines Logo
6:00 am - 9:40 amCLT-BRU
21h 40m2 stops
Multiple Airlines Logo
9:05 pm - 9:47 pmBRU-CLT
29h 42m2 stops
$614Multiple Airlines
Find Deal
Fri, Oct 24 - Thu, Oct 30
Air Canada Logo
6:00 am - 7:50 amCLT-BRU
20h 50m2 stops
Air Canada Logo
10:00 am - 8:57 pmBRU-CLT
16h 57m2 stops
$653Air Canada
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Wed, Oct 29 - Sun, Nov 9
KLM Logo
5:43 pm - 9:00 amCHS-BRU
33h 17m1 stop
KLM Logo
6:15 am - 3:43 pmBRU-CHS
15h 28m2 stops
$1,481KLM
Find Deal
Sat, Dec 20 - Fri, Jan 2

Air Canada flights from South Carolina to Brussels Bruxelles-National Airport

Our best Air Canada deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
Air Canada
Nov 16
CLT5:05 pmCharlotte Douglas
14h 10m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Dec 2
BRU10:00 amBrussels Bruxelles-National
16h 57m
2 stops
CLT8:57 pmCharlotte Douglas
$559
Find similar
Air Canada
Oct 29
CLT6:00 amCharlotte Douglas
20h 50m
2 stops
BRU7:50 amBrussels Bruxelles-National
Nov 9
BRU10:00 amBrussels Bruxelles-National
16h 57m
2 stops
CLT8:57 pmCharlotte Douglas
$653
Find similar
Air Canada
Dec 26
CLT5:15 pmCharlotte Douglas
32h 35m
2 stops
BRU7:50 amBrussels Bruxelles-National
Jan 17
BRU10:00 amBrussels Bruxelles-National
36h 17m
2 stops
CLT4:17 pmCharlotte Douglas
$695
Find similar

United Airlines flights from South Carolina to Brussels Bruxelles-National Airport

Our best United Airlines deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
United Airlines
Mar 10
CLT2:30 pmCharlotte Douglas
12h 35m
1 stop
BRU8:05 amBrussels Bruxelles-National
Mar 18
BRU10:00 amBrussels Bruxelles-National
31h 48m
2 stops
CLT12:48 pmCharlotte Douglas
$574
Find similar
United Airlines
Jan 13
CLT2:20 pmCharlotte Douglas
11h 45m
1 stop
BRU8:05 amBrussels Bruxelles-National
Jan 21
BRU11:55 amBrussels Bruxelles-National
13h 04m
1 stop
CLT6:59 pmCharlotte Douglas
$597
Find similar
United Airlines
Oct 26
CHS6:15 amCharleston
26h 00m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Nov 2
BRU11:55 amBrussels Bruxelles-National
33h 14m
1 stop
CHS3:09 pmCharleston
$611
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 25, 2025.
Use the filters below to find and compare flights from South Carolina to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 11/19

1:22 pm-2:30 pm

2 stops19h 08m

Brussels Bruxelles-National

Sun 11/23

8:30 pm-11:50 pm

2 stops33h 20m

$526

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Thu 11/13

10:02 am-7:50 pm

2 stops27h 48m

Brussels Bruxelles-National

Mon 11/17

10:20 am-9:26 pm

2 stops17h 06m

$527

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 11/16

5:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

Tue 12/2

10:00 am-8:57 pm

2 stops16h 57m

$559

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 3/10

2:30 pm-8:05 am

1 stop12h 35m

Brussels Bruxelles-National

Wed 3/18

10:00 am-12:48 pm

2 stops31h 48m

$574

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 11/16

5:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

Tue 12/2

9:35 am-4:55 pm

1 stop13h 20m

$586

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 11/16

1:22 pm-9:00 am

1 stop13h 38m

Brussels Bruxelles-National

Tue 12/2

11:00 am-6:05 pm

1 stop13h 05m

$596

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 1/13

2:20 pm-8:05 am

1 stop11h 45m

Brussels Bruxelles-National

Wed 1/21

11:55 am-6:59 pm

1 stop13h 04m

$597

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Fri 10/24

6:00 am-9:40 am

2 stops21h 40m

Brussels Bruxelles-National

Thu 10/30

9:05 pm-9:47 pm

2 stops29h 42m

$614

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 10/29

6:00 am-7:50 am

2 stops20h 50m

Brussels Bruxelles-National

Sun 11/9

10:00 am-8:57 pm

2 stops16h 57m

$653

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Sat 12/20

5:43 pm-9:00 am

1 stop33h 17m

Brussels Bruxelles-National

Fri 1/2

6:15 am-3:43 pm

2 stops15h 28m

$1,481

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from South Carolina to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Brussels Bruxelles-National Airport?

The cheapest day to depart from South Carolina to Brussels Bruxelles-National Airport is on a Thursday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Thursday will often find tickets for as low as $855. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from South Carolina to Brussels Bruxelles-National Airport for around $1,022.

What is the cheapest time of day to depart on your flight to Brussels Bruxelles-National Airport?

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is in the morning. Flights from South Carolina to Brussels Bruxelles-National Airport during this time can be as low as $931. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $1,075 on average. Flights to Brussels Bruxelles-National Airport from South Carolina in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on South Carolina to Brussels Bruxelles-National Airport flights?

You could potentially save up to 19% on your flight if you consider stops on a South Carolina to Brussels Bruxelles-National Airport flight.

Cheap South Carolina to Brussels Bruxelles-National Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Brussels Bruxelles-National Airport

Direct flights

None
There are no direct flights from South Carolina to Brussels Bruxelles-National Airport. There are no popular flight routes from South Carolina to Brussels Bruxelles-National Airport.
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  • When did momondo last update prices for flights from South Carolina to Brussels Bruxelles-National Airport?

    Prices for flights from South Carolina to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from South Carolina to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from South Carolina to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $591Free CancellationRating
7.4
8,928 reviews
Search United Airlines flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Bruges
Ghent
Leuven
Charleroi
Hasselt
Spa
Namur
Aalst
Dinant
Mons
Zaventem
Waterloo
Genk
Mechelen
Francorchamps
Knokke-Heist
Tournai
Durbuy
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Brussels?

Finding the right flight to Brussels from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Brussels quick and easy, saving you time and money.

Can I find flights from South Carolina to Brussels with flexible booking policies on momondo?

All flight searches from South Carolina to Brussels on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Brussels?

momondo provides multiple filters to help you find the best flight to Brussels from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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