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Cheap flights from South Carolina to Brussels from $480

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Brussels departing on 1/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from South Carolina to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
8:00 am - 1:15 pmCAE-BRU
23h 15m2 stops
United Airlines Logo
10:00 am - 4:26 pmBRU-CAE
36h 26m2 stops
$480United Airlines
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Wed, Jan 7 - Wed, Jan 14
United Airlines Logo
1:25 pm - 8:05 amMYR-BRU
12h 40m1 stop
United Airlines Logo
10:00 am - 12:41 pmBRU-MYR
32h 41m2 stops
$484United Airlines
Find Deal
Tue, Jan 6 - Tue, Jan 13
Air Canada Logo
6:00 am - 7:50 amCHS-BRU
19h 50m2 stops
Air Canada Logo
10:00 am - 5:59 pmBRU-CHS
37h 59m2 stops
$484Air Canada
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Wed, Jan 28 - Sun, Feb 1
Scandinavian Airlines Logo
10:00 am - 8:30 pmCLT-BRU
28h 30m2 stops
Scandinavian Airlines Logo
11:20 am - 10:23 pmBRU-CLT
41h 03m2 stops
$493Scandinavian Airlines
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Mon, Apr 13 - Tue, Apr 21
United Airlines Logo
1:25 pm - 8:55 amMYR-BRU
37h 30m2 stops
United Airlines Logo
10:00 am - 12:41 pmBRU-MYR
32h 41m2 stops
$499United Airlines
Find Deal
Tue, Jan 6 - Tue, Jan 13
United Airlines Logo
2:58 pm - 1:15 pmCHS-BRU
16h 17m2 stops
United Airlines Logo
11:55 am - 7:04 pmBRU-CHS
13h 09m1 stop
$503United Airlines
Find Deal
Wed, Jan 28 - Sun, Feb 1
Brussels Airlines Logo
2:58 pm - 7:15 amCHS-BRU
10h 17m1 stop
Brussels Airlines Logo
11:55 am - 7:04 pmBRU-CHS
13h 09m1 stop
$507Brussels Airlines
Find Deal
Wed, Jan 28 - Sun, Feb 1
Scandinavian Airlines Logo
10:00 am - 7:50 pmCLT-BRU
27h 50m2 stops
Scandinavian Airlines Logo
10:20 am - 11:06 pmBRU-CLT
18h 46m2 stops
$546Scandinavian Airlines
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Tue, Jan 13 - Wed, Jan 21
Lufthansa Logo
2:54 pm - 7:15 amCLT-BRU
10h 21m1 stop
Lufthansa Logo
11:55 am - 6:59 pmBRU-CLT
13h 04m1 stop
$563Lufthansa
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Mon, Jan 12 - Tue, Jan 27
Lufthansa Logo
2:54 pm - 7:15 amCLT-BRU
10h 21m1 stop
Lufthansa Logo
11:55 am - 6:59 pmBRU-CLT
13h 04m1 stop
$603Lufthansa
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Tue, Jan 13 - Wed, Jan 21

United Airlines flights from South Carolina to Brussels Bruxelles-National Airport

Our best United Airlines deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
United Airlines
Jan 7
CAE8:00 amColumbia Metropolitan
23h 15m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Jan 14
BRU10:00 amBrussels Bruxelles-National
36h 26m
2 stops
CAE4:26 pmColumbia Metropolitan
$480
Find similar
United Airlines
Jan 6
MYR1:25 pmMyrtle Beach Intl
12h 40m
1 stop
BRU8:05 amBrussels Bruxelles-National
Jan 13
BRU10:00 amBrussels Bruxelles-National
32h 41m
2 stops
MYR12:41 pmMyrtle Beach Intl
$484
Find similar
United Airlines
Jan 6
MYR1:25 pmMyrtle Beach Intl
37h 30m
2 stops
BRU8:55 amBrussels Bruxelles-National
Jan 13
BRU10:00 amBrussels Bruxelles-National
32h 41m
2 stops
MYR12:41 pmMyrtle Beach Intl
$499
Find similar

Air Canada flights from South Carolina to Brussels Bruxelles-National Airport

Our best Air Canada deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
Air Canada
Jan 28
CHS6:00 amCharleston
19h 50m
2 stops
BRU7:50 amBrussels Bruxelles-National
Feb 1
BRU10:00 amBrussels Bruxelles-National
37h 59m
2 stops
CHS5:59 pmCharleston
$484
Find similar
Air Canada
May 18
CLT8:30 amCharlotte Douglas
22h 45m
2 stops
BRU1:15 pmBrussels Bruxelles-National
May 27
BRU10:00 amBrussels Bruxelles-National
29h 44m
2 stops
CLT9:44 amCharlotte Douglas
$729
Find similar
Air Canada
May 18
CLT8:30 amCharlotte Douglas
22h 45m
2 stops
BRU1:15 pmBrussels Bruxelles-National
May 27
BRU10:00 amBrussels Bruxelles-National
34h 31m
2 stops
CLT2:31 pmCharlotte Douglas
$730
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 23, 2025.
Use the filters below to find and compare flights from South Carolina to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Wed 1/7

8:00 am-1:15 pm

2 stops23h 15m

Brussels Bruxelles-National

Wed 1/14

10:00 am-4:26 pm

2 stops36h 26m

$480

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Tue 1/6

1:25 pm-8:05 am

1 stop12h 40m

Brussels Bruxelles-National

Tue 1/13

10:00 am-12:41 pm

2 stops32h 41m

$484

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 1/28

6:00 am-7:50 am

2 stops19h 50m

Brussels Bruxelles-National

Sun 2/1

10:00 am-5:59 pm

2 stops37h 59m

$484

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Mon 4/13

10:00 am-8:30 pm

2 stops28h 30m

Brussels Bruxelles-National

Tue 4/21

11:20 am-10:23 pm

2 stops41h 03m

$493

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Tue 1/6

1:25 pm-8:55 am

2 stops37h 30m

Brussels Bruxelles-National

Tue 1/13

10:00 am-12:41 pm

2 stops32h 41m

$499

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 1/28

2:58 pm-1:15 pm

2 stops16h 17m

Brussels Bruxelles-National

Sun 2/1

11:55 am-7:04 pm

1 stop13h 09m

$503

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 1/28

2:58 pm-7:15 am

1 stop10h 17m

Brussels Bruxelles-National

Sun 2/1

11:55 am-7:04 pm

1 stop13h 09m

$507

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 1/13

10:00 am-7:50 pm

2 stops27h 50m

Brussels Bruxelles-National

Wed 1/21

10:20 am-11:06 pm

2 stops18h 46m

$546

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Mon 1/12

2:54 pm-7:15 am

1 stop10h 21m

Brussels Bruxelles-National

Tue 1/27

11:55 am-6:59 pm

1 stop13h 04m

$563

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 1/13

2:54 pm-7:15 am

1 stop10h 21m

Brussels Bruxelles-National

Wed 1/21

11:55 am-6:59 pm

1 stop13h 04m

$603

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Brussels from

How to get the cheapest flight ticket from South Carolina to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Brussels Bruxelles-National Airport?

The cheapest day to depart from South Carolina to Brussels Bruxelles-National Airport is on a Thursday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Thursday will often find tickets for as low as $855. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from South Carolina to Brussels Bruxelles-National Airport for around $1,022.

What is the cheapest time of day to depart on your flight to Brussels Bruxelles-National Airport?

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is in the morning. Flights from South Carolina to Brussels Bruxelles-National Airport during this time can be as low as $931. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $1,075 on average. Flights to Brussels Bruxelles-National Airport from South Carolina in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on South Carolina to Brussels Bruxelles-National Airport flights?

You could potentially save up to 24% on your flight if you consider stops on a South Carolina to Brussels Bruxelles-National Airport flight.

Cheap South Carolina to Brussels Bruxelles-National Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Brussels Bruxelles-National Airport

Direct flights

None
There are no direct flights from South Carolina to Brussels Bruxelles-National Airport. There are no popular flight routes from South Carolina to Brussels Bruxelles-National Airport.
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  • When did momondo last update prices for flights from South Carolina to Brussels Bruxelles-National Airport?

    Prices for flights from South Carolina to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from South Carolina to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from South Carolina to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $591Free CancellationRating
7.4
9,036 reviews
Search United Airlines flights

Traveling to a place near Brussels?

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Ghent
Bruges
Leuven
Charleroi
Hasselt
Spa
Zaventem
Namur
Dinant
Mons
Genk
Waterloo
Mechelen
Durbuy
Francorchamps
Knokke-Heist
Aalst
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Brussels?

Finding the right flight to Brussels from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Brussels quick and easy, saving you time and money.

Can I find flights from South Carolina to Brussels with flexible booking policies on momondo?

All flight searches from South Carolina to Brussels on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Brussels?

momondo provides multiple filters to help you find the best flight to Brussels from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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