Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from South Carolina to Brussels from $214

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Brussels departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from South Carolina to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
1:11 pm - 8:55 am
CHS
-
BRU
13h 44m1 stop
United Airlines Logo
10:00 am - 1:52 pm
BRU
-
CHS
33h 52m2 stops
$438United Airlines
Tue, Feb 17 - Tue, Feb 24
United Airlines Logo
1:11 pm - 7:50 am
CHS
-
BRU
36h 39m2 stops
United Airlines Logo
10:00 am - 1:52 pm
BRU
-
CHS
33h 52m2 stops
$442United Airlines
Tue, Feb 17 - Tue, Feb 24
United Airlines Logo
10:20 am - 8:55 am
CHS
-
BRU
16h 35m1 stop
United Airlines Logo
11:55 am - 7:00 pm
BRU
-
CHS
13h 05m1 stop
$458United Airlines
Tue, Feb 17 - Tue, Feb 24
British Airways Logo
11:06 am - 1:50 pm
CHS
-
BRU
20h 44m2 stops
British Airways Logo
11:50 am - 11:59 pm
BRU
-
CHS
18h 09m2 stops
$459British Airways
Wed, Feb 25 - Wed, Mar 4
Air Canada Logo
10:00 am - 7:50 am
CHS
-
BRU
15h 50m2 stops
Air Canada Logo
10:00 am - 11:44 pm
BRU
-
CHS
43h 44m2 stops
$467Air Canada
Fri, Feb 13 - Thu, Feb 26
Multiple Airlines Logo
6:00 am - 7:50 am
CHS
-
BRU
19h 50m3 stops
Multiple Airlines Logo
10:00 am - 8:59 am
BRU
-
CHS
28h 59m2 stops
$473Multiple Airlines
Tue, Feb 17 - Tue, Feb 24
American Airlines Logo
5:40 pm - 4:20 pm
MYR
-
BRU
16h 40m2 stops
American Airlines Logo
11:50 am - 10:56 pm
BRU
-
MYR
17h 06m2 stops
$474American Airlines
Wed, Feb 18 - Wed, Feb 25
American Airlines Logo
6:15 pm - 1:35 pm
CAE
-
BRU
13h 20m2 stops
American Airlines Logo
12:00 pm - 10:56 pm
BRU
-
CAE
16h 56m2 stops
$474American Airlines
Tue, Feb 24 - Tue, Mar 3
Air Canada Logo
7:50 am - 1:15 pm
CLT
-
BRU
23h 25m2 stops
Air Canada Logo
10:00 am - 8:57 pm
BRU
-
CLT
16h 57m2 stops
$487Air Canada
Sun, Feb 8 - Tue, Feb 24
Multiple Airlines Logo
7:50 am - 1:15 pm
CLT
-
BRU
23h 25m2 stops
Multiple Airlines Logo
9:05 am - 4:55 pm
BRU
-
CLT
13h 50m1 stop
$488Multiple Airlines
Sun, Feb 8 - Tue, Feb 24

British Airways flights from South Carolina to Brussels Bruxelles-National Airport

Our best British Airways deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
British Airways
Feb 25
CHS11:06 amCharleston
20h 44m
2 stops
BRU1:50 pmBrussels Bruxelles-National
Mar 4
BRU11:50 amBrussels Bruxelles-National
18h 09m
2 stops
CHS11:59 pmCharleston
$459
British Airways
Mar 14
CLT4:47 pmCharlotte Douglas
18h 48m
2 stops
BRU4:35 pmBrussels Bruxelles-National
Mar 23
BRU8:45 pmBrussels Bruxelles-National
25h 05m
1 stop
CLT4:50 pmCharlotte Douglas
$549
British Airways
Apr 2
CLT7:56 pmCharlotte Douglas
31h 59m
2 stops
BRU9:55 amBrussels Bruxelles-National
Apr 13
BRU9:55 pmBrussels Bruxelles-National
29h 42m
2 stops
CLT9:37 pmCharlotte Douglas
$608

Air Canada flights from South Carolina to Brussels Bruxelles-National Airport

Our best Air Canada deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
Air Canada
Feb 13
CHS10:00 amCharleston
15h 50m
2 stops
BRU7:50 amBrussels Bruxelles-National
Feb 26
BRU10:00 amBrussels Bruxelles-National
43h 44m
2 stops
CHS11:44 pmCharleston
$467
Air Canada
Feb 8
CLT7:50 amCharlotte Douglas
23h 25m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Feb 24
BRU10:00 amBrussels Bruxelles-National
16h 57m
2 stops
CLT8:57 pmCharlotte Douglas
$487
Air Canada
Feb 8
CLT7:50 amCharlotte Douglas
23h 25m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Feb 24
BRU10:00 amBrussels Bruxelles-National
16h 57m
2 stops
CLT8:57 pmCharlotte Douglas
$490

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from South Carolina to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 2/17

1:11 pm-8:55 am

1 stop13h 44m

Brussels Bruxelles-National

Tue 2/24

10:00 am-1:52 pm

2 stops33h 52m

$438

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 2/17

1:11 pm-7:50 am

2 stops36h 39m

Brussels Bruxelles-National

Tue 2/24

10:00 am-1:52 pm

2 stops33h 52m

$442

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 2/17

10:20 am-8:55 am

1 stop16h 35m

Brussels Bruxelles-National

Tue 2/24

11:55 am-7:00 pm

1 stop13h 05m

$458

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Wed 2/25

11:06 am-1:50 pm

2 stops20h 44m

Brussels Bruxelles-National

Wed 3/4

11:50 am-11:59 pm

2 stops18h 09m

$459

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Fri 2/13

10:00 am-7:50 am

2 stops15h 50m

Brussels Bruxelles-National

Thu 2/26

10:00 am-11:44 pm

2 stops43h 44m

$467

CharlestonBrussels

CHS - BRU

CHSBRU

Charleston

Tue 2/17

6:00 am-7:50 am

3 stops19h 50m

Brussels Bruxelles-National

Tue 2/24

10:00 am-8:59 am

2 stops28h 59m

$473

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Wed 2/18

5:40 pm-4:20 pm

2 stops16h 40m

Brussels Bruxelles-National

Wed 2/25

11:50 am-10:56 pm

2 stops17h 06m

$474

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Tue 2/24

6:15 pm-1:35 pm

2 stops13h 20m

Brussels Bruxelles-National

Tue 3/3

12:00 pm-10:56 pm

2 stops16h 56m

$474

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 2/8

7:50 am-1:15 pm

2 stops23h 25m

Brussels Bruxelles-National

Tue 2/24

10:00 am-8:57 pm

2 stops16h 57m

$487

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 2/8

7:50 am-1:15 pm

2 stops23h 25m

Brussels Bruxelles-National

Tue 2/24

9:05 am-4:55 pm

1 stop13h 50m

$488

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to Brussels from

How to get the cheapest flight ticket from South Carolina to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Brussels Bruxelles-National Airport flights?

You could potentially save up to 1% on your flight if you consider stops on a South Carolina to Brussels Bruxelles-National Airport flight.

Cheap South Carolina to Brussels Bruxelles-National Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Brussels Bruxelles-National Airport

Fastest flight time

10h 27m

Direct flights

None
The fastest flight from South Carolina to Brussels Bruxelles-National Airport takes 10h 27m
There are no direct flights from South Carolina to Brussels Bruxelles-National Airport. There are no popular flight routes from South Carolina to Brussels Bruxelles-National Airport.
Search flight deals

  • When did momondo last update prices for flights from South Carolina to Brussels Bruxelles-National Airport?

    Prices for flights from South Carolina to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from South Carolina to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from South Carolina to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $591Free CancellationRating
7.4
9,143 reviews
Search United Airlines flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Bruges
Ghent
Leuven
Charleroi
Hasselt
Spa
Zaventem
Namur
Dinant
Genk
Mons
Waterloo
Durbuy
Aalst
Mechelen
Francorchamps
Knokke-Heist
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Brussels?

Finding the right flight to Brussels from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Brussels quick and easy, saving you time and money.

Can I find flights from South Carolina to Brussels with flexible booking policies on momondo?

All flight searches from South Carolina to Brussels on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Brussels?

momondo provides multiple filters to help you find the best flight to Brussels from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Brussels Bruxelles-National Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 2/11
Wed 2/18
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Brussels

Popular cities in Belgium

Popular flights according to clicks in the last 7 days on momondo
Flights to Charleroi Brussels Airportfrom $411