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Cheap flights from South Carolina to Brussels from $350

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Brussels departing on 9/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from South Carolina to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:55 pm - 3:05 pm
CLT
-
BRU
15h 10m
1 stop
American Airlines Logo
4:00 pm - 1:15 pm
BRU
-
CLT
27h 15m
1 stop
$822American Airlines
Wed, Sep 9 - Wed, Sep 16
Air Canada Logo
9:20 am - 7:50 am
CLT
-
BRU
16h 30m
1 stop
Air Canada Logo
9:40 am - 2:57 pm
BRU
-
CLT
11h 17m
1 stop
$825Air Canada
Mon, May 11 - Tue, May 26
Multiple Airlines Logo
10:10 am - 7:10 am
CLT
-
BRU
15h 00m
2 stops
Multiple Airlines Logo
10:15 am - 5:11 pm
BRU
-
CLT
12h 56m
1 stop
$826Multiple Airlines
Tue, May 12 - Tue, May 19
American Airlines Logo
4:15 pm - 3:05 pm
CLT
-
BRU
16h 50m
2 stops
American Airlines Logo
4:00 pm - 1:15 pm
BRU
-
CLT
27h 15m
1 stop
$827American Airlines
Wed, Sep 9 - Wed, Sep 16
United Airlines Logo
6:25 pm - 8:00 pm
CLT
-
BRU
19h 35m
2 stops
United Airlines Logo
9:55 am - 1:42 pm
BRU
-
CLT
33h 47m
2 stops
$829United Airlines
Tue, May 12 - Tue, May 19
Air Canada Logo
9:20 am - 7:50 am
CLT
-
BRU
16h 30m
1 stop
Air Canada Logo
9:40 am - 2:57 pm
BRU
-
CLT
11h 17m
1 stop
$830Air Canada
Sun, May 10 - Tue, May 26
United Airlines Logo
2:49 pm - 7:15 am
CLT
-
BRU
10h 26m
1 stop
United Airlines Logo
9:55 am - 1:42 pm
BRU
-
CLT
33h 47m
2 stops
$833United Airlines
Tue, May 12 - Tue, May 19
Lufthansa Logo
2:49 pm - 7:15 am
CLT
-
BRU
10h 26m
1 stop
Lufthansa Logo
12:00 pm - 6:55 pm
BRU
-
CLT
12h 55m
1 stop
$840Lufthansa
Tue, May 12 - Tue, May 19
Scandinavian Airlines Logo
2:15 pm - 9:40 am
MYR
-
BRU
37h 25m
2 stops
Scandinavian Airlines Logo
5:45 am - 11:39 pm
BRU
-
MYR
23h 54m
2 stops
$856Scandinavian Airlines
Thu, Sep 3 - Mon, Sep 14
Scandinavian Airlines Logo
4:01 pm - 9:40 am
CAE
-
BRU
35h 39m
2 stops
Scandinavian Airlines Logo
10:20 am - 9:11 pm
BRU
-
CAE
16h 51m
2 stops
$1,182Scandinavian Airlines
Sun, Apr 26 - Thu, Apr 30

American Airlines flights from South Carolina to Brussels Bruxelles-National Airport

Our best American Airlines deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
American Airlines
Sep 9
CLT5:55 pmCharlotte Douglas
15h 10m
1 stop
BRU3:05 pmBrussels Bruxelles-National
Sep 16
BRU4:00 pmBrussels Bruxelles-National
27h 15m
1 stop
CLT1:15 pmCharlotte Douglas
$822
American Airlines
Sep 9
CLT4:15 pmCharlotte Douglas
16h 50m
2 stops
BRU3:05 pmBrussels Bruxelles-National
Sep 16
BRU4:00 pmBrussels Bruxelles-National
27h 15m
1 stop
CLT1:15 pmCharlotte Douglas
$827
American Airlines
Sep 9
CLT4:15 pmCharlotte Douglas
16h 50m
2 stops
BRU3:05 pmBrussels Bruxelles-National
Sep 16
BRU11:00 amBrussels Bruxelles-National
16h 55m
2 stops
CLT9:55 pmCharlotte Douglas
$837

United Airlines flights from South Carolina to Brussels Bruxelles-National Airport

Our best United Airlines deals on South Carolina to Brussels Bruxelles-National Airport flight tickets
United Airlines
May 12
CLT6:25 pmCharlotte Douglas
19h 35m
2 stops
BRU8:00 pmBrussels Bruxelles-National
May 19
BRU9:55 amBrussels Bruxelles-National
33h 47m
2 stops
CLT1:42 pmCharlotte Douglas
$829
United Airlines
May 12
CLT2:49 pmCharlotte Douglas
10h 26m
1 stop
BRU7:15 amBrussels Bruxelles-National
May 19
BRU9:55 amBrussels Bruxelles-National
33h 47m
2 stops
CLT1:42 pmCharlotte Douglas
$833
United Airlines
May 10
CLT6:15 amCharlotte Douglas
20h 45m
1 stop
BRU9:00 amBrussels Bruxelles-National
May 26
BRU11:10 amBrussels Bruxelles-National
13h 52m
2 stops
CLT7:02 pmCharlotte Douglas
$845

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 13, 2026.
Use the filters below to find and compare flights from South Carolina to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 9/9

5:55 pm-3:05 pm

1 stop15h 10m

Brussels Bruxelles-National

Wed 9/16

4:00 pm-1:15 pm

1 stop27h 15m

$822

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Mon 5/11

9:20 am-7:50 am

1 stop16h 30m

Brussels Bruxelles-National

Tue 5/26

9:40 am-2:57 pm

1 stop11h 17m

$825

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 5/12

10:10 am-7:10 am

2 stops15h 00m

Brussels Bruxelles-National

Tue 5/19

10:15 am-5:11 pm

1 stop12h 56m

$826

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Wed 9/9

4:15 pm-3:05 pm

2 stops16h 50m

Brussels Bruxelles-National

Wed 9/16

4:00 pm-1:15 pm

1 stop27h 15m

$827

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 5/12

6:25 pm-8:00 pm

2 stops19h 35m

Brussels Bruxelles-National

Tue 5/19

9:55 am-1:42 pm

2 stops33h 47m

$829

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Sun 5/10

9:20 am-7:50 am

1 stop16h 30m

Brussels Bruxelles-National

Tue 5/26

9:40 am-2:57 pm

1 stop11h 17m

$830

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 5/12

2:49 pm-7:15 am

1 stop10h 26m

Brussels Bruxelles-National

Tue 5/19

9:55 am-1:42 pm

2 stops33h 47m

$833
Quickest round-trip

CharlotteBrussels

CLT - BRU

CLTBRU

Charlotte Douglas

Tue 5/12

2:49 pm-7:15 am

1 stop10h 26m

Brussels Bruxelles-National

Tue 5/19

12:00 pm-6:55 pm

1 stop12h 55m

$840

Myrtle BeachBrussels

MYR - BRU

MYRBRU

Myrtle Beach Intl

Thu 9/3

2:15 pm-9:40 am

2 stops37h 25m

Brussels Bruxelles-National

Mon 9/14

5:45 am-11:39 pm

2 stops23h 54m

$856

ColumbiaBrussels

CAE - BRU

CAEBRU

Columbia Metropolitan

Sun 4/26

4:01 pm-9:40 am

2 stops35h 39m

Brussels Bruxelles-National

Thu 4/30

10:20 am-9:11 pm

2 stops16h 51m

$1,182

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from South Carolina to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on South Carolina to Brussels Bruxelles-National Airport flights?

You could potentially save up to 61% on your flight if you consider stops on a South Carolina to Brussels Bruxelles-National Airport flight.

Cheap South Carolina to Brussels Bruxelles-National Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Brussels Bruxelles-National Airport

Fastest flight time

11h 18m

Direct flights

None
The fastest flight from South Carolina to Brussels Bruxelles-National Airport takes 11h 18m
There are no direct flights from South Carolina to Brussels Bruxelles-National Airport. There are no popular flight routes from South Carolina to Brussels Bruxelles-National Airport.
Search flight deals

Frequently asked questions about flying from South Carolina to Brussels Bruxelles-National Airport

  • When did momondo last update prices for flights from South Carolina to Brussels Bruxelles-National Airport?

    Prices for flights from South Carolina to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from South Carolina to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from South Carolina to Brussels Bruxelles-National Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from South Carolina to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $603Free CancellationRating
7.4
9,579 reviews
Search United Airlines flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Ghent
Bruges
Leuven
Charleroi
Hasselt
Zaventem
Namur
Genk
Waterloo
Dinant
Durbuy
Mons
Aalst
Mechelen
Knokke-Heist
Spa
Francorchamps
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Brussels?

Finding the right flight to Brussels from South Carolina is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Brussels quick and easy, saving you time and money.

Can I find flights from South Carolina to Brussels with flexible booking policies on momondo?

All flight searches from South Carolina to Brussels on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from South Carolina to Brussels?

momondo provides multiple filters to help you find the best flight to Brussels from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Brussels Bruxelles-National Airport trip

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