Cheap flights from Santa Ana, California to Panama City from $325

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Panama City departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Santa Ana, California to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:26 pm - 6:37 pm
SNA
-
PTY
22h 11m
2 stops
United Airlines Logo
3:30 pm - 9:07 am
PTY
-
SNA
19h 37m
2 stops
$723United Airlines
Mon, Jun 15 - Mon, Jun 22
United Airlines Logo
6:20 pm - 2:14 pm
SNA
-
PTY
17h 54m
2 stops
United Airlines Logo
3:30 pm - 9:07 am
PTY
-
SNA
19h 37m
2 stops
$743United Airlines
Wed, Jun 3 - Mon, Jun 22
United Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
United Airlines Logo
10:00 am - 9:01 am
PTY
-
SNA
25h 01m
3 stops
$749United Airlines
Sat, Aug 22 - Wed, Aug 26
United Airlines Logo
7:00 pm - 2:14 pm
SNA
-
PTY
17h 14m
2 stops
United Airlines Logo
10:00 am - 9:01 am
PTY
-
SNA
25h 01m
3 stops
$753United Airlines
Sat, Aug 22 - Wed, Aug 26
United Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
United Airlines Logo
10:00 am - 9:45 pm
PTY
-
SNA
13h 45m
1 stop
$759United Airlines
Tue, May 19 - Tue, May 26
United Airlines Logo
4:00 pm - 2:14 pm
SNA
-
PTY
20h 14m
2 stops
United Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
$763United Airlines
Tue, Jun 2 - Tue, Jun 9
Copa Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
Copa Airlines Logo
10:00 am - 9:53 pm
PTY
-
SNA
13h 53m
1 stop
$768Copa Airlines
Thu, Aug 20 - Mon, Aug 24
United Airlines Logo
3:05 pm - 4:12 pm
SNA
-
PTY
23h 07m
1 stop
United Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
$774United Airlines
Tue, Jun 2 - Tue, Jun 9
Multiple Airlines Logo
7:45 pm - 10:30 am
SNA
-
PTY
12h 45m
2 stops
Multiple Airlines Logo
5:30 am - 6:02 pm
PTY
-
SNA
14h 32m
2 stops
$777Multiple Airlines
Sat, May 9 - Wed, May 13
United Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
United Airlines Logo
3:30 pm - 9:15 am
PTY
-
SNA
19h 45m
2 stops
$783United Airlines
Fri, Aug 21 - Fri, Aug 28

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United Airlines flights from Santa Ana, California to Panama City

Our best United Airlines deals on Santa Ana, California to Panama City flight tickets
United Airlines
Jun 15
SNA6:26 pmSanta Ana J. Wayne/Orange Cnty
22h 11m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Jun 22
PTY3:30 pmPanama City Tocumen Intl
19h 37m
2 stops
SNA9:07 amSanta Ana J. Wayne/Orange Cnty
$723
United Airlines
Jun 3
SNA6:20 pmSanta Ana J. Wayne/Orange Cnty
17h 54m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Jun 22
PTY3:30 pmPanama City Tocumen Intl
19h 37m
2 stops
SNA9:07 amSanta Ana J. Wayne/Orange Cnty
$743
United Airlines
Aug 22
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 26
PTY10:00 amPanama City Tocumen Intl
25h 01m
3 stops
SNA9:01 amSanta Ana J. Wayne/Orange Cnty
$749

Copa Airlines flights from Santa Ana, California to Panama City

Our best Copa Airlines deals on Santa Ana, California to Panama City flight tickets
Copa Airlines
Aug 20
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 24
PTY10:00 amPanama City Tocumen Intl
13h 53m
1 stop
SNA9:53 pmSanta Ana J. Wayne/Orange Cnty
$768
Copa Airlines
Sep 1
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 8
PTY3:30 pmPanama City Tocumen Intl
21h 47m
1 stop
SNA11:17 amSanta Ana J. Wayne/Orange Cnty
$786
Copa Airlines
Sep 11
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 15
PTY10:00 amPanama City Tocumen Intl
13h 53m
1 stop
SNA9:53 pmSanta Ana J. Wayne/Orange Cnty
$798

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Mon 6/15

6:26 pm-6:37 pm

2 stops22h 11m

Panama City Tocumen Intl

Mon 6/22

3:30 pm-9:07 am

2 stops19h 37m

$723

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Wed 6/3

6:20 pm-2:14 pm

2 stops17h 54m

Panama City Tocumen Intl

Mon 6/22

3:30 pm-9:07 am

2 stops19h 37m

$743

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 8/22

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Wed 8/26

10:00 am-9:01 am

3 stops25h 01m

$749

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 8/22

7:00 pm-2:14 pm

2 stops17h 14m

Panama City Tocumen Intl

Wed 8/26

10:00 am-9:01 am

3 stops25h 01m

$753
Quickest round-trip

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 5/19

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Tue 5/26

10:00 am-9:45 pm

1 stop13h 45m

$759

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

4:00 pm-2:14 pm

2 stops20h 14m

Panama City Tocumen Intl

Tue 6/9

7:55 am-9:45 pm

1 stop15h 50m

$763

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Thu 8/20

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Mon 8/24

10:00 am-9:53 pm

1 stop13h 53m

$768

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Tue 6/2

3:05 pm-4:12 pm

1 stop23h 07m

Panama City Tocumen Intl

Tue 6/9

7:55 am-9:45 pm

1 stop15h 50m

$774

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Sat 5/9

7:45 pm-10:30 am

2 stops12h 45m

Panama City Tocumen Intl

Wed 5/13

5:30 am-6:02 pm

2 stops14h 32m

$777

Santa AnaPanama City

SNA - PTY

SNAPTY

Santa Ana J. Wayne/Orange Cnty

Fri 8/21

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Fri 8/28

3:30 pm-9:15 am

2 stops19h 45m

$783

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Santa Ana, California to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $610. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $669. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Santa Ana, California to Panama City during this time can be as low as $612. Try not to purchase tickets in the evening because they tend to be around $635. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Santa Ana, California to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Panama City (SNA to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Panama City

Fastest flight time

8h 37m

Direct flights

None
The fastest flight from Santa Ana, California to Panama City takes 8h 37m
There are no direct flights from Santa Ana, California to Panama City. There are no popular flight routes from Santa Ana, California to Panama City.

Frequently asked questions about flying from Santa Ana, California to Panama City

  • How far is Santa Ana J. Wayne/Orange Cnty to Panama City Tocumen Intl by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Panama City Tocumen Intl will travel around 2971.5 mi. In terms of flight time, this usually takes a little over 8h 37m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Santa Ana to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Santa Ana to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santa Ana to Panama City.

I’m not ready to book a flight from Santa Ana to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Santa Ana and alert you when they change.

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1 adult
Sun 5/24
Sun 5/31

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