Cheap flights from San Pedro Sula to Panama City from $128

In general, June is the cheapest month to fly from San Pedro Sula to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $299. If you’re not able to fly to Panama City in June, then January is your next best option. Flight prices from San Pedro Sula to Panama City during January average around $305.

Our data shows that Monday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $371. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $443. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from San Pedro Sula to Panama City during this time can be as low as $371. Try not to purchase tickets in the morning because they tend to be around $458. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from San Pedro Sula Ramon Villeda to Panama City Tocumen Intl for the best San Pedro Sula Ramon Villeda - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from San Pedro Sula when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $343 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Pedro Sula for as low as $314 on momondo.

There are 2 cabin classes available to choose from on San Pedro Sula Ramon Villeda to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Historically, on average around 3% of flights between San Pedro Sula and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 107 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 3% of their flights experiencing any sort of delay.

1 flights are operational daily from San Pedro Sula to Panama City as of February 2026. The most popular departure time for this route is 1:00PM, with 62% of flights per day taking off in the afternoon.

As of February 2026, there are 12 flights per week flying from San Pedro Sula to Panama City. The most common day of the week flights depart is Sat, with 50% of flights taking off on this day.