Cheap flights from San Pedro Sula to Panama City from $188

In general, March is the cheapest month to fly from San Pedro Sula to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $305. If you’re not able to fly to Panama City in March, then February is your next best option. Flight prices from San Pedro Sula to Panama City during February average around $305.

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $399. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $489. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from San Pedro Sula to Panama City during this time can be as low as $414. Try not to purchase tickets at noon because they tend to be around $438. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from San Pedro Sula Ramon Villeda to Panama City Tocumen Intl for the best San Pedro Sula Ramon Villeda - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from San Pedro Sula when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $361 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from San Pedro Sula for as low as $306 on momondo.

There are 2 cabin classes available to choose from on San Pedro Sula to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between San Pedro Sula to Panama City.

As of June 2026, prices for San Pedro Sula to Panama City flights are approximately 11% more expensive when compared to flights at the same time last year.

Historically, on average around 3% of flights between San Pedro Sula and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 100 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 3% of their flights experiencing any sort of delay.

2 flights are operational daily from San Pedro Sula to Panama City as of June 2026. The most popular departure time for this route is 1:00PM, with 72% of flights per day taking off in the afternoon.

As of June 2026, there are 20 flights per week flying from San Pedro Sula to Panama City. The most common day of the week flights depart is Wed, with 30% of flights taking off on this day.