Cheap flights from Rome to Brussels from $45

The cheapest month to fly to Brussels Bruxelles-National Airport from Rome is in February. Flight prices, which tend to average around $122, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Brussels Bruxelles-National Airport from Rome during March instead. Flights to Brussels Bruxelles-National Airport in March, while not as cheap as those in February, still average around $129.

The cheapest day to depart from Rome to Brussels Bruxelles-National Airport is on a Saturday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Saturday will often find tickets for as low as $121. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Rome to Brussels Bruxelles-National Airport for around $311.

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is at noon. Flights from Rome to Brussels Bruxelles-National Airport during this time can be as low as $147. If you have a flexible travel schedule, then try to avoid flying in the evening when prices are $328 on average. Flights to Brussels Bruxelles-National Airport from Rome in the evening are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Rome Fiumicino to Brussels Bruxelles-National for the best Rome - Brussels Bruxelles-National flight prices

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Rome when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $171 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Rome for as low as $108 on momondo.

There are 2 cabin classes available to choose from on Rome to Brussels Bruxelles-National Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

easyJet, Vueling, and Ryanair are the most popular carriers operating from Rome to Brussels Bruxelles-National

easyJet, Brussels Airlines and Ryanair are the top three most popular airlines that fly to Brussels Bruxelles-National Airport from Rome according to our data. easyJet is the first choice among our users, with 41% of people opting to fly with this airline when traveling to Brussels Bruxelles-National Airport. Keep in mind that there are 3 different airlines that fly to Brussels Bruxelles-National Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 17% of flights between Rome and Brussels have experienced a delay on any given week. The average delay length over the past 12 months has been 106 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, ITA Airways have had the least number of delays on this route over the last 12 months; with about 9% of their flights experiencing any sort of delay.

The number of flights available between Rome and Brussels Bruxelles-National Airport is 8 per day as of August 2026. The most frequent departure time is 6:00PM, with 45% of daily flights leaving at noon.

61 flights are operational weekly from Rome to Brussels Bruxelles-National Airport as of August 2026. The most popular departure day for this route is Fri, with 23% of flights per week taking off on this day.