Which airport is the most popular layover for flights between Minneapolis and Panama City?

Chicago (ORD) was the most common stop: 43% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Minneapolis to Panama City?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 7h 40m.

What is the cheapest airline that flies from Minneapolis St Paul to Panama City Tocumen Intl?

United Airlines is the most popular carrier operating from Minneapolis St Paul to Panama City Tocumen Intl

What airlines fly to Panama City?

United Airlines, Delta and Copa Airlines are the top three most popular airlines that fly to Panama City from Minneapolis according to our data. United Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from Minneapolis to Panama City?

Atlanta (ATL) has the shortest average layover time for this route: 1h 56m.

Which layover airport offers the lowest fares from Minneapolis to Panama City?

Flights via Atlanta (ATL) offer the lowest average round-trip price of $613.

When did momondo last update prices for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

Prices for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport were last updated today.

How many operators does momondo search for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

The number of operators available for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport is 4 as of October 2026.

How old do you have to be to fly from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$232 Cheap Flights from Minneapolis to Panama City in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Minneapolis to Panama City

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:30 am - 5:12 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

8h 42m1 stop Houston George Bush Intcntl

8:55 am - 5:11 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

9h 16m1 stop Houston George Bush Intcntl

$529United Airlines

Wed, Feb 10 - Tue, Feb 23

7:30 am - 5:12 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

8h 42m1 stop Houston George Bush Intcntl

8:55 am - 11:15 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

15h 20m1 stop Houston George Bush Intcntl

$529United Airlines

Tue, Jan 26 - Mon, Feb 1

6:00 am - 3:20 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

8h 20m1 stop Miami

3:13 pm - 12:43 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

21h 30m2 stops Miami Washington, D.C. Reagan-National

$533American Airlines

Tue, Mar 9 - Tue, Mar 16

5:21 pm - 1:26 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

19h 05m2 stops Charlotte Douglas Miami

2:26 pm - 8:33 amPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

19h 07m2 stops Miami Chicago O'Hare Intl

$533American Airlines

Mon, Jan 25 - Wed, Feb 3

5:50 pm - 2:45 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

19h 55m1 stop Houston George Bush Intcntl

8:55 am - 11:15 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

15h 20m1 stop Houston George Bush Intcntl

$621Copa Airlines

Thu, Jan 21 - Mon, Feb 1

11:29 am - 2:45 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

26h 16m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

8:55 am - 7:44 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

11h 49m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$623Copa Airlines

Wed, Dec 2 - Wed, Dec 9

6:00 am - 3:55 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

8h 55m1 stop Miami

2:26 pm - 11:59 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

10h 33m1 stop Miami

$715GOL

Sat, Jan 23 - Sun, Jan 31

6:25 am - 1:55 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

30h 30m1 stop Atlanta Hartsfield-Jackson

1:40 pm - 7:01 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

30h 21m1 stop Atlanta Hartsfield-Jackson

$756Delta

Tue, Jan 5 - Sat, Jan 16

8:55 am - 12:15 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

26h 20m1 stop Atlanta Hartsfield-Jackson

3:20 pm - 1:54 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

23h 34m1 stop Atlanta Hartsfield-Jackson

$756Delta

Fri, Jan 15 - Tue, Jan 26

6:00 am - 3:55 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

8h 55m1 stop Miami

2:26 pm - 11:59 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

10h 33m1 stop Miami

$787GOL

Mon, Jan 25 - Sun, Jan 31

Cheap last minute flights

Enter your travel dates to find the best prices.

1:54 pm - 1:02 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

23h 08m2 stops Charlotte Douglas Miami

2:02 pm - 11:59 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

9h 57m1 stop Miami

$758American Airlines

Fri, Oct 9 - Mon, Oct 12

1:54 pm - 1:02 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

23h 08m2 stops Charlotte Douglas Miami

2:02 pm - 1:30 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

23h 28m2 stops Miami Chicago O'Hare Intl

$758American Airlines

Fri, Oct 9 - Mon, Oct 12

8:03 pm - 7:31 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

23h 28m1 stop Newark

3:30 pm - 5:31 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

26h 01m1 stop Houston George Bush Intcntl

$782United Airlines

Fri, Oct 9 - Mon, Oct 12

6:15 am - 7:31 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

13h 16m1 stop Newark

9:45 am - 11:42 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

13h 57m1 stop Newark

$919United Airlines

Mon, Oct 5 - Wed, Oct 7

7:40 am - 6:37 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

10h 57m1 stop Houston George Bush Intcntl

10:00 am - 10:54 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

12h 54m1 stop Houston George Bush Intcntl

$919United Airlines

Mon, Oct 5 - Wed, Oct 7

7:40 am - 6:37 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

10h 57m1 stop Houston George Bush Intcntl

9:45 am - 11:42 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

13h 57m1 stop Newark

$922Copa Airlines

Mon, Oct 5 - Wed, Oct 7

3:23 pm - 1:02 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

21h 39m2 stops Dallas/Fort Worth Miami

2:02 pm - 11:59 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

9h 57m1 stop Miami

$924American Airlines

Mon, Oct 5 - Wed, Oct 7

8:03 pm - 7:31 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

23h 28m1 stop Newark

9:45 am - 11:42 pmPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

13h 57m1 stop Newark

$936Copa Airlines

Sun, Oct 4 - Wed, Oct 7

5:59 pm - 1:02 pmMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

19h 03m2 stops Charlotte Douglas Miami

2:02 pm - 9:30 amPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

19h 28m2 stops Miami Dallas/Fort Worth

$1,021GOL

Mon, Oct 5 - Wed, Oct 7

9:33 am - 9:15 amMSP Minneapolis St Paul-PTY Panama City Tocumen Intl

23h 42m3 stops Atlanta Hartsfield-Jackson Orlando Bogotá El Dorado

4:25 am - 12:06 amPTY Panama City Tocumen Intl-MSP Minneapolis St Paul

19h 41m3 stops Bogotá El Dorado Orlando Denver Intl

$1,135Multiple Airlines

Fri, Oct 9 - Mon, Oct 12

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

American Airlines flights from Minneapolis to Panama City

Our best American Airlines deals on Minneapolis to Panama City flight tickets

American Airlines

Feb 10

MSP4:11 pmMinneapolis St Paul

22h 03m

2 stops

PTY3:14 pmPanama City Tocumen Intl

Feb 23

PTY4:04 pmPanama City Tocumen Intl

21h 38m

2 stops

MSP12:42 pmMinneapolis St Paul

$554

American Airlines

Mar 9

MSP5:05 pmMinneapolis St Paul

21h 15m

2 stops

PTY3:20 pmPanama City Tocumen Intl

Mar 16

PTY3:13 pmPanama City Tocumen Intl

19h 55m

2 stops

MSP11:08 amMinneapolis St Paul

$572

American Airlines

Feb 10

MSP4:11 pmMinneapolis St Paul

22h 03m

2 stops

PTY3:14 pmPanama City Tocumen Intl

Feb 23

PTY4:04 pmPanama City Tocumen Intl

22h 03m

2 stops

MSP1:07 pmMinneapolis St Paul

$578

Copa Airlines flights from Minneapolis to Panama City

Our best Copa Airlines deals on Minneapolis to Panama City flight tickets

Copa Airlines

Jan 21

MSP5:50 pmMinneapolis St Paul

19h 55m

1 stop

PTY2:45 pmPanama City Tocumen Intl

Feb 1

PTY8:55 amPanama City Tocumen Intl

15h 20m

1 stop

MSP11:15 pmMinneapolis St Paul

$621

Copa Airlines

Dec 2

MSP11:29 amMinneapolis St Paul

28h 43m

2 stops

PTY5:12 pmPanama City Tocumen Intl

Dec 9

PTY11:35 amPanama City Tocumen Intl

12h 24m

1 stop

MSP10:59 pmMinneapolis St Paul

$623

Copa Airlines

Oct 17

MSP11:22 amMinneapolis St Paul

9h 19m

1 stop

PTY8:41 pmPanama City Tocumen Intl

Oct 19

PTY10:29 pmPanama City Tocumen Intl

11h 54m

1 stop

MSP10:23 amMinneapolis St Paul

$829

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Wed 2/10

7:30 am-5:12 pm

1 stop8h 42m

Panama City Tocumen Intl

Tue 2/23

8:55 am-5:11 pm

1 stop9h 16m

$529

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Tue 1/26

7:30 am-5:12 pm

1 stop8h 42m

Panama City Tocumen Intl

Mon 2/1

8:55 am-11:15 pm

1 stop15h 20m

$529

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Tue 3/9

6:00 am-3:20 pm

1 stop8h 20m

Panama City Tocumen Intl

Tue 3/16

3:13 pm-12:43 pm

2 stops21h 30m

$533

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 1/25

5:21 pm-1:26 pm

2 stops19h 05m

Panama City Tocumen Intl

Wed 2/3

2:26 pm-8:33 am

2 stops19h 07m

$533

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Thu 1/21

5:50 pm-2:45 pm

1 stop19h 55m

Panama City Tocumen Intl

Mon 2/1

8:55 am-11:15 pm

1 stop15h 20m

$621

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Wed 12/2

11:29 am-2:45 pm

2 stops26h 16m

Panama City Tocumen Intl

Wed 12/9

8:55 am-7:44 pm

2 stops11h 49m

$623

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Sat 1/23

6:00 am-3:55 pm

1 stop8h 55m

Panama City Tocumen Intl

Sun 1/31

2:26 pm-11:59 pm

1 stop10h 33m

$715

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Tue 1/5

6:25 am-1:55 pm

1 stop30h 30m

Panama City Tocumen Intl

Sat 1/16

1:40 pm-7:01 pm

1 stop30h 21m

$756

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Fri 1/15

8:55 am-12:15 pm

1 stop26h 20m

Panama City Tocumen Intl

Tue 1/26

3:20 pm-1:54 pm

1 stop23h 34m

$756

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 1/25

6:00 am-3:55 pm

1 stop8h 55m

Panama City Tocumen Intl

Sun 1/31

2:26 pm-11:59 pm

1 stop10h 33m

$787

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Minneapolis to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Minneapolis and Panama City?

Prices are currently low for flights on this route.

Typical prices usually range from $763 to $914.
The lowest price recently found on this route was $529.

What is the cheapest month to fly to Panama City?

In general, April is the cheapest month to fly from Minneapolis to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $741. If you’re not able to fly to Panama City in April, then March is your next best option. Flight prices from Minneapolis to Panama City during March average around $743.

When to book flights from Minneapolis to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Panama City according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Minneapolis to Panama City (MSP to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Panama City

Best Price Found	$232
Fastest flight time	8h 12m
Direct flights	None

The best one-way flight to Panama City from Minneapolis in the past 72 hours is $232. The best round-trip flight deal from Minneapolis to Panama City found on momondo in the last 72 hours is $529.

The fastest flight from Minneapolis to Panama City takes 8h 12m

There are no direct flights from Minneapolis to Panama City. There are no popular flight routes from Minneapolis to Panama City.

Search flight deals

Frequently asked questions about flying from Minneapolis to Panama City

How far is Minneapolis St Paul to Panama City Tocumen Intl by plane?
There are 2616.9 mi between Minneapolis St Paul and Panama City Tocumen Intl. By plane, this route typically takes 8h 12m.
When did momondo last update prices for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?
Prices for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport were last updated today.
How many operators does momondo search for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?
The number of operators available for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport is 4 as of October 2026.
How old do you have to be to fly from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Minneapolis to Panama City?
momondo data reveals that the most frequently booked airline on the route from Minneapolis to Panama City is United Airlines, representing 45% of all bookings. The subsequent popular airlines are Delta at 21%, Copa Airlines at 20%, and American Airlines at 14%.

Best airlines flying from Minneapolis to Panama City

Compare and see reviews for airlines that fly from Minneapolis to Panama City with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $573	Free Cancellation	Rating 7.4 10,280 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $577	Free Cancellation	Rating 7.6 1,545 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $636	Free Cancellation	Rating 7.0 12,128 reviews	Search American Airlines flights
Delta	PriceFrom $704	Free Cancellation	Rating 7.8 8,627 reviews	Search Delta flights

San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Panama City?

Finding the right flight to Panama City from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Minneapolis to Panama City with flexible booking policies on momondo?

All flight searches from Minneapolis to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Minneapolis to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Minneapolis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Minneapolis to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Minneapolis to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Mon 11/2

Mon 11/9

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Nearby airports

Airlines

Cabin classes

Other Panama destinations

Other flights from Minneapolis

Complete your trip

Feeling lucky

Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from Minneapolis to Panama City from $232

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Panama City departing on 11/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Minneapolis to Panama City

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

American Airlines flights from Minneapolis to Panama City

Our best American Airlines deals on Minneapolis to Panama City flight tickets

Copa Airlines flights from Minneapolis to Panama City

Our best Copa Airlines deals on Minneapolis to Panama City flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Minneapolis to Panama City that are best for you.

See travel insights to Panama City from

How to get the cheapest flight ticket from Minneapolis to Panama City

What is the typical price of a round-trip flight between Minneapolis and Panama City?

What is the cheapest month to fly to Panama City?

What is the cheapest airline that flies from Minneapolis St Paul to Panama City Tocumen Intl?

What airlines fly to Panama City?

Which airport is the most popular layover for flights between Minneapolis and Panama City?

Which layover airport offers the lowest fares from Minneapolis to Panama City?

Which layover airport has the shortest travel time from Minneapolis to Panama City?

Which layover airport has the shortest connection time from Minneapolis to Panama City?

When to book flights from Minneapolis to Panama City

Cheap Minneapolis to Panama City (MSP to PTY) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Minneapolis to Panama City

Best airlines flying from Minneapolis to Panama City

Compare and see reviews for airlines that fly from Minneapolis to Panama City with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Airports servicing Panama

Fly your favorite airline to Panama City

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama City

List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Minneapolis

According to popular flight searches on momondo this year

Complete your trip to Panama City

Explore popular destinations other users love

According to popular flight searches on momondo this year