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Cheap flights from Minneapolis to Panama City from $300

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Panama City departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Minneapolis to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 2:22 pm
MSP
-
PTY
8h 22m1 stop
American Airlines Logo
3:13 pm - 12:49 am
PTY
-
MSP
9h 36m1 stop
$614American Airlines
Tue, Mar 17 - Thu, Apr 2
American Airlines Logo
6:09 pm - 2:22 pm
MSP
-
PTY
20h 13m2 stops
American Airlines Logo
3:13 pm - 11:08 am
PTY
-
MSP
19h 55m2 stops
$618American Airlines
Tue, Mar 17 - Thu, Apr 2
United Airlines Logo
5:19 pm - 1:45 pm
MSP
-
PTY
20h 26m2 stops
United Airlines Logo
10:55 pm - 3:50 pm
PTY
-
MSP
16h 55m2 stops
$643United Airlines
Sun, Mar 15 - Sun, Mar 22
American Airlines Logo
6:00 am - 2:22 pm
MSP
-
PTY
8h 22m1 stop
American Airlines Logo
3:13 pm - 12:49 am
PTY
-
MSP
9h 36m1 stop
$647American Airlines
Tue, Mar 10 - Tue, Mar 31
American Airlines Logo
3:01 pm - 1:50 pm
MSP
-
PTY
21h 49m2 stops
American Airlines Logo
1:44 pm - 12:49 am
PTY
-
MSP
11h 05m1 stop
$651American Airlines
Wed, Mar 4 - Wed, Mar 18
United Airlines Logo
7:30 am - 1:45 pm
MSP
-
PTY
30h 15m1 stop
United Airlines Logo
10:55 pm - 3:50 pm
PTY
-
MSP
16h 55m2 stops
$655United Airlines
Sun, Mar 15 - Sun, Mar 22
American Airlines Logo
6:00 am - 1:50 pm
MSP
-
PTY
30h 50m1 stop
American Airlines Logo
1:55 pm - 10:32 pm
PTY
-
MSP
8h 37m1 stop
$663American Airlines
Wed, Mar 4 - Tue, Apr 14
American Airlines Logo
6:00 am - 3:15 pm
MSP
-
PTY
8h 15m1 stop
American Airlines Logo
1:44 pm - 12:49 am
PTY
-
MSP
11h 05m1 stop
$667American Airlines
Mon, Mar 2 - Wed, Mar 18
United Airlines Logo
9:55 am - 4:10 am
MSP
-
PTY
18h 15m2 stops
United Airlines Logo
3:30 pm - 2:23 pm
PTY
-
MSP
22h 53m2 stops
$668United Airlines
Fri, Mar 27 - Fri, Apr 3
United Airlines Logo
7:30 am - 5:07 pm
MSP
-
PTY
8h 37m1 stop
United Airlines Logo
7:55 am - 11:15 pm
PTY
-
MSP
15h 20m1 stop
$679United Airlines
Thu, Mar 5 - Tue, Mar 17

American Airlines flights from Minneapolis to Panama City

Our best American Airlines deals on Minneapolis to Panama City flight tickets
American Airlines
Mar 17
MSP6:00 amMinneapolis St Paul
8h 22m
1 stop
PTY2:22 pmPanama City Tocumen Intl
Apr 2
PTY3:13 pmPanama City Tocumen Intl
9h 36m
1 stop
MSP12:49 amMinneapolis St Paul
$614
Find similar
American Airlines
Mar 17
MSP6:09 pmMinneapolis St Paul
20h 13m
2 stops
PTY2:22 pmPanama City Tocumen Intl
Apr 2
PTY3:13 pmPanama City Tocumen Intl
19h 55m
2 stops
MSP11:08 amMinneapolis St Paul
$618
Find similar
American Airlines
Mar 10
MSP6:00 amMinneapolis St Paul
8h 22m
1 stop
PTY2:22 pmPanama City Tocumen Intl
Mar 31
PTY3:13 pmPanama City Tocumen Intl
9h 36m
1 stop
MSP12:49 amMinneapolis St Paul
$647
Find similar

Copa Airlines flights from Minneapolis to Panama City

Our best Copa Airlines deals on Minneapolis to Panama City flight tickets
Copa Airlines
Feb 14
MSP4:52 pmMinneapolis St Paul
11h 41m
1 stop
PTY5:33 amPanama City Tocumen Intl
Feb 28
PTY7:55 amPanama City Tocumen Intl
10h 33m
1 stop
MSP5:28 pmMinneapolis St Paul
$730
Find similar
Copa Airlines
Jan 14
MSP9:55 amMinneapolis St Paul
9h 40m
1 stop
PTY8:35 pmPanama City Tocumen Intl
Jan 21
PTY12:56 pmPanama City Tocumen Intl
11h 42m
1 stop
MSP11:38 pmMinneapolis St Paul
$774
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Minneapolis to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 3/17

6:00 am-2:22 pm

1 stop8h 22m

Panama City Tocumen Intl

Thu 4/2

3:13 pm-12:49 am

1 stop9h 36m

$614

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 3/17

6:09 pm-2:22 pm

2 stops20h 13m

Panama City Tocumen Intl

Thu 4/2

3:13 pm-11:08 am

2 stops19h 55m

$618

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 3/15

5:19 pm-1:45 pm

2 stops20h 26m

Panama City Tocumen Intl

Sun 3/22

10:55 pm-3:50 pm

2 stops16h 55m

$643

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 3/10

6:00 am-2:22 pm

1 stop8h 22m

Panama City Tocumen Intl

Tue 3/31

3:13 pm-12:49 am

1 stop9h 36m

$647

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 3/4

3:01 pm-1:50 pm

2 stops21h 49m

Panama City Tocumen Intl

Wed 3/18

1:44 pm-12:49 am

1 stop11h 05m

$651

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 3/15

7:30 am-1:45 pm

1 stop30h 15m

Panama City Tocumen Intl

Sun 3/22

10:55 pm-3:50 pm

2 stops16h 55m

$655

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 3/4

6:00 am-1:50 pm

1 stop30h 50m

Panama City Tocumen Intl

Tue 4/14

1:55 pm-10:32 pm

1 stop8h 37m

$663

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 3/2

6:00 am-3:15 pm

1 stop8h 15m

Panama City Tocumen Intl

Wed 3/18

1:44 pm-12:49 am

1 stop11h 05m

$667

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Fri 3/27

9:55 am-4:10 am

2 stops18h 15m

Panama City Tocumen Intl

Fri 4/3

3:30 pm-2:23 pm

2 stops22h 53m

$668

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Thu 3/5

7:30 am-5:07 pm

1 stop8h 37m

Panama City Tocumen Intl

Tue 3/17

7:55 am-11:15 pm

1 stop15h 20m

$679

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Minneapolis to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, July is the cheapest month to fly from Minneapolis to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $693. If you’re not able to fly to Panama City in July, then November is your next best option. Flight prices from Minneapolis to Panama City during November average around $726.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $757. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $861. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Minneapolis to Panama City during this time can be as low as $746. Try not to purchase tickets in the morning because they tend to be around $817. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $847 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Minneapolis for as low as $607 on momondo.

When to book flights from Minneapolis to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Minneapolis to Panama City (MSP to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Panama City

Fastest flight time

8h 07m

Direct flights

None
The fastest flight from Minneapolis to Panama City takes 8h 07m
There are no direct flights from Minneapolis to Panama City. There are no popular flight routes from Minneapolis to Panama City.
Search flight deals

  • How far is Minneapolis St Paul to Panama City Tocumen Intl by plane?

    There are 2616.9 mi between Minneapolis St Paul and Panama City Tocumen Intl. By plane, this route typically takes 8h 07m.

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Minneapolis to Panama City?

Best airlines flying from Minneapolis to Panama City

Compare and see reviews for airlines that fly from Minneapolis to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $603Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
United AirlinesPriceFrom $607Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights
DeltaPriceFrom $638Free CancellationRating
7.9
8,007 reviews
Search Delta flights
Copa AirlinesPriceFrom $719Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Panama City?

Finding the right flight to Panama City from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Minneapolis to Panama City with flexible booking policies on momondo?

All flight searches from Minneapolis to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Minneapolis to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Minneapolis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Minneapolis to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Minneapolis to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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