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Cheap flights from Minneapolis to Panama City from $390

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Panama City departing on 9/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Minneapolis to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:33 pm - 5:33 amMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
15h 00m1 stop Denver Intl
Multiple Airlines Logo
12:56 pm - 12:08 amPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
11h 12m1 stop Denver Intl
$661Multiple Airlines
Sat, Sep 19 - Sat, Sep 26
Multiple Airlines Logo
2:33 pm - 5:33 amMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
15h 00m1 stop Denver Intl
Multiple Airlines Logo
12:56 pm - 12:08 amPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
11h 12m1 stop Denver Intl
$673Multiple Airlines
Sat, Sep 19 - Sat, Sep 26
Delta Logo
6:05 pm - 1:55 pmMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
18h 50m1 stop Atlanta Hartsfield-Jackson
Delta Logo
3:20 pm - 1:54 pmPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
23h 34m1 stop Atlanta Hartsfield-Jackson
$717Delta
Mon, Jan 18 - Thu, Jan 28
Delta Logo
8:15 pm - 1:55 pmMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
16h 40m1 stop Atlanta Hartsfield-Jackson
Delta Logo
3:20 pm - 1:54 pmPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
23h 34m1 stop Atlanta Hartsfield-Jackson
$717Delta
Sun, Jan 17 - Thu, Jan 28
United Airlines Logo
8:00 am - 5:12 pmMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
8h 12m1 stop Houston George Bush Intcntl
United Airlines Logo
8:55 am - 11:05 pmPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
15h 10m1 stop Houston George Bush Intcntl
$725United Airlines
Thu, Jan 21 - Thu, Jan 28
United Airlines Logo
8:00 am - 7:38 pmMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
10h 38m1 stop Houston George Bush Intcntl
United Airlines Logo
11:35 am - 11:05 pmPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
12h 30m1 stop Houston George Bush Intcntl
$725United Airlines
Wed, Jan 20 - Wed, Jan 27
American Airlines Logo
6:00 am - 3:38 pmMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
8h 38m1 stop Miami
American Airlines Logo
4:46 pm - 2:52 pmPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
23h 06m2 stops Miami Chicago O'Hare Intl
$729American Airlines
Tue, Jan 26 - Thu, Feb 4
American Airlines Logo
6:19 pm - 3:38 pmMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
20h 19m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
4:46 pm - 3:01 pmPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
23h 15m2 stops Miami Charlotte Douglas
$729American Airlines
Mon, Jan 11 - Fri, Jan 22
Copa Airlines Logo
11:45 am - 8:35 pmMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
8h 50m1 stop Washington, D.C. Dulles Intl
Copa Airlines Logo
8:05 am - 5:39 pmPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
10h 34m1 stop Chicago O'Hare Intl
$915Copa Airlines
Wed, Oct 28 - Fri, Nov 13
Copa Airlines Logo
7:40 am - 6:37 pmMSP  Minneapolis St Paul-PTY Panama City Tocumen Intl
10h 57m1 stop Houston George Bush Intcntl
Copa Airlines Logo
3:30 pm - 10:20 amPTY  Panama City Tocumen Intl-MSP Minneapolis St Paul
18h 50m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$974Copa Airlines
Thu, Oct 1 - Sun, Oct 4

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American Airlines flights from Minneapolis to Panama City

Our best American Airlines deals on Minneapolis to Panama City flight tickets
American Airlines
Sep 30
MSP11:02 amMinneapolis St Paul
25h 14m
2 stops
PTY12:16 pmPanama City Tocumen Intl
Nov 18
PTY3:13 pmPanama City Tocumen Intl
19h 00m
2 stops
MSP9:13 amMinneapolis St Paul
$747
American Airlines
Dec 10
MSP5:03 pmMinneapolis St Paul
20h 10m
2 stops
PTY2:13 pmPanama City Tocumen Intl
Dec 20
PTY4:33 pmPanama City Tocumen Intl
18h 42m
2 stops
MSP10:15 amMinneapolis St Paul
$759
American Airlines
Sep 30
MSP6:15 amMinneapolis St Paul
30h 01m
1 stop
PTY12:16 pmPanama City Tocumen Intl
Nov 18
PTY3:13 pmPanama City Tocumen Intl
9h 19m
1 stop
MSP11:32 pmMinneapolis St Paul
$761

Delta flights from Minneapolis to Panama City

Our best Delta deals on Minneapolis to Panama City flight tickets
Delta
Jan 17
MSP8:15 pmMinneapolis St Paul
16h 40m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 27
PTY3:20 pmPanama City Tocumen Intl
20h 17m
1 stop
MSP10:37 amMinneapolis St Paul
$717
Delta
Dec 10
MSP5:24 amMinneapolis St Paul
7h 41m
1 stop
PTY2:05 pmPanama City Tocumen Intl
Dec 20
PTY8:00 amPanama City Tocumen Intl
13h 56m
1 stop
MSP8:56 pmMinneapolis St Paul
$730
Delta
Jan 17
MSP8:15 pmMinneapolis St Paul
16h 40m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 26
PTY3:20 pmPanama City Tocumen Intl
18h 50m
1 stop
MSP9:10 amMinneapolis St Paul
$738

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Minneapolis to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Sat 9/19

2:33 pm-5:33 am

1 stop15h 00m

Panama City Tocumen Intl

Sat 9/26

12:56 pm-12:08 am

1 stop11h 12m

$661

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Sat 9/19

2:33 pm-5:33 am

1 stop15h 00m

Panama City Tocumen Intl

Sat 9/26

12:56 pm-12:08 am

1 stop11h 12m

$673

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 1/18

6:05 pm-1:55 pm

1 stop18h 50m

Panama City Tocumen Intl

Thu 1/28

3:20 pm-1:54 pm

1 stop23h 34m

$717

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Sun 1/17

8:15 pm-1:55 pm

1 stop16h 40m

Panama City Tocumen Intl

Thu 1/28

3:20 pm-1:54 pm

1 stop23h 34m

$717

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Thu 1/21

8:00 am-5:12 pm

1 stop8h 12m

Panama City Tocumen Intl

Thu 1/28

8:55 am-11:05 pm

1 stop15h 10m

$725

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Wed 1/20

8:00 am-7:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Wed 1/27

11:35 am-11:05 pm

1 stop12h 30m

$725

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Tue 1/26

6:00 am-3:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Thu 2/4

4:46 pm-2:52 pm

2 stops23h 06m

$729

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Mon 1/11

6:19 pm-3:38 pm

2 stops20h 19m

Panama City Tocumen Intl

Fri 1/22

4:46 pm-3:01 pm

2 stops23h 15m

$729
Quickest round-trip

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Wed 10/28

11:45 am-8:35 pm

1 stop8h 50m

Panama City Tocumen Intl

Fri 11/13

8:05 am-5:39 pm

1 stop10h 34m

$915

MinneapolisPanama City

MSP Minneapolis St Paul - PTY Panama City Tocumen Intl

MSPPTY

Minneapolis St Paul

Thu 10/1

7:40 am-6:37 pm

1 stop10h 57m

Panama City Tocumen Intl

Sun 10/4

3:30 pm-10:20 am

2 stops18h 50m

$974

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Minneapolis to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Minneapolis and Panama City?

Prices are currently low for flights on this route.

Typical prices usually range from $798 to $1,326.
The lowest price recently found on this route was $661.

What is the cheapest month to fly to Panama City?

In general, November is the cheapest month to fly from Minneapolis to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $716. If you’re not able to fly to Panama City in November, then March is your next best option. Flight prices from Minneapolis to Panama City during March average around $724.

When to book flights from Minneapolis to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Minneapolis to Panama City (MSP to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Panama City

Fastest flight time

7h 28m

Direct flights

None
The fastest flight from Minneapolis to Panama City takes 7h 28m
There are no direct flights from Minneapolis to Panama City. There are no popular flight routes from Minneapolis to Panama City.
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Frequently asked questions about flying from Minneapolis to Panama City

  • How far is Minneapolis St Paul to Panama City Tocumen Intl by plane?

    There are 2616.9 mi between Minneapolis St Paul and Panama City Tocumen Intl. By plane, this route typically takes 7h 28m.

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Minneapolis to Panama City?

Best airlines flying from Minneapolis to Panama City

Compare and see reviews for airlines that fly from Minneapolis to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $607Free CancellationRating
7.4
10,089 reviews
Search United Airlines flights
American AirlinesPriceFrom $636Free CancellationRating
7.1
11,892 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $646Free CancellationRating
7.6
1,563 reviews
Search Copa Airlines flights
DeltaPriceFrom $704Free CancellationRating
7.8
8,496 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Panama City?

Finding the right flight to Panama City from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Minneapolis to Panama City with flexible booking policies on momondo?

All flight searches from Minneapolis to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Minneapolis to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Minneapolis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Minneapolis to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Minneapolis to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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