Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Chicago Midway Airport to Brussels from $348

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Brussels departing on 3/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago Midway Airport to Brussels

Cheap round-trip flights

Delta Logo
9:32 am - 9:00 amMDW-BRU
16h 28m2 stops
Delta Logo
11:00 am - 11:32 pmBRU-MDW
19h 32m2 stops
$771Delta
Find Deal
Sun, Nov 9 - Tue, Nov 18
Delta Logo
1:08 pm - 7:35 amMDW-BRU
11h 27m2 stops
Delta Logo
11:00 am - 11:32 pmBRU-MDW
19h 32m2 stops
$837Delta
Find Deal
Thu, Nov 6 - Thu, Nov 13
Delta Logo
9:29 am - 10:10 amMDW-BRU
17h 41m2 stops
Delta Logo
8:05 am - 6:08 pmBRU-MDW
17h 03m2 stops
$849Delta
Find Deal
Thu, Jan 1 - Fri, Jan 16
Multiple Airlines Logo
9:35 am - 8:05 amMDW-BRU
15h 30m2 stops
Multiple Airlines Logo
10:00 am - 4:24 pmBRU-MDW
13h 24m2 stops
$869Multiple Airlines
Find Deal
Thu, Oct 2 - Wed, Oct 8
Multiple Airlines Logo
9:35 am - 11:00 amMDW-BRU
18h 25m3 stops
Multiple Airlines Logo
10:00 am - 4:24 pmBRU-MDW
13h 24m2 stops
$889Multiple Airlines
Find Deal
Thu, Oct 2 - Wed, Oct 8
Delta Logo
9:29 am - 10:10 amMDW-BRU
17h 41m2 stops
Delta Logo
8:05 am - 6:34 pmBRU-MDW
17h 29m2 stops
$907Delta
Find Deal
Thu, Jan 1 - Fri, Jan 16
Delta Logo
1:00 pm - 10:10 amMDW-BRU
38h 10m2 stops
Delta Logo
2:45 pm - 6:34 pmBRU-MDW
33h 49m2 stops
$999Delta
Find Deal
Wed, Mar 4 - Sun, Mar 8
Delta Logo
1:08 pm - 10:10 amMDW-BRU
14h 02m2 stops
Delta Logo
2:45 pm - 11:32 pmBRU-MDW
15h 47m2 stops
$1,049Delta
Find Deal
Thu, Nov 6 - Sun, Nov 9
KLM Logo
10:35 am - 8:40 amMDW-BRU
15h 05m1 stop
KLM Logo
10:45 am - 5:35 pmBRU-MDW
13h 50m1 stop
$1,957KLM
Find Deal
Tue, Sep 30 - Fri, Oct 3
KLM Logo
6:30 pm - 8:40 amMDW-BRU
31h 10m1 stop
KLM Logo
6:10 am - 3:26 pmBRU-MDW
16h 16m2 stops
$2,112KLM
Find Deal
Wed, Oct 1 - Sat, Oct 4

Delta flights from Chicago Midway Airport to Brussels Bruxelles-National Airport

Our best Delta deals on Chicago Midway Airport to Brussels Bruxelles-National Airport flight tickets
Delta
Nov 9
MDW9:32 amChicago Midway
16h 28m
2 stops
BRU9:00 amBrussels Bruxelles-National
Nov 18
BRU11:00 amBrussels Bruxelles-National
19h 32m
2 stops
MDW11:32 pmChicago Midway
$771
Find similar
Delta
Nov 6
MDW1:08 pmChicago Midway
11h 27m
2 stops
BRU7:35 amBrussels Bruxelles-National
Nov 13
BRU11:00 amBrussels Bruxelles-National
19h 32m
2 stops
MDW11:32 pmChicago Midway
$837
Find similar
Delta
Jan 1
MDW9:29 amChicago Midway
17h 41m
2 stops
BRU10:10 amBrussels Bruxelles-National
Jan 16
BRU8:05 amBrussels Bruxelles-National
17h 03m
2 stops
MDW6:08 pmChicago Midway
$849
Find similar

KLM flights from Chicago Midway Airport to Brussels Bruxelles-National Airport

Our best KLM deals on Chicago Midway Airport to Brussels Bruxelles-National Airport flight tickets
KLM
Sep 30
MDW10:35 amChicago Midway
15h 05m
1 stop
BRU8:40 amBrussels Bruxelles-National
Oct 3
BRU10:45 amBrussels Bruxelles-National
13h 50m
1 stop
MDW5:35 pmChicago Midway
$1,957
Find similar
KLM
Sep 29
MDW6:30 pmChicago Midway
31h 10m
1 stop
BRU8:40 amBrussels Bruxelles-National
Oct 2
BRU10:45 amBrussels Bruxelles-National
17h 51m
2 stops
MDW9:36 pmChicago Midway
$1,979
Find similar
KLM
Sep 25
MDW6:00 amChicago Midway
19h 40m
1 stop
BRU8:40 amBrussels Bruxelles-National
Sep 28
BRU10:45 amBrussels Bruxelles-National
17h 51m
1 stop
MDW9:36 pmChicago Midway
$2,076
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 18, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 11/9

9:32 am-9:00 am

2 stops16h 28m

Brussels Bruxelles-National

Tue 11/18

11:00 am-11:32 pm

2 stops19h 32m

$771

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 11/6

1:08 pm-7:35 am

2 stops11h 27m

Brussels Bruxelles-National

Thu 11/13

11:00 am-11:32 pm

2 stops19h 32m

$837

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 1/1

9:29 am-10:10 am

2 stops17h 41m

Brussels Bruxelles-National

Fri 1/16

8:05 am-6:08 pm

2 stops17h 03m

$849

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 10/2

9:35 am-8:05 am

2 stops15h 30m

Brussels Bruxelles-National

Wed 10/8

10:00 am-4:24 pm

2 stops13h 24m

$869

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 10/2

9:35 am-11:00 am

3 stops18h 25m

Brussels Bruxelles-National

Wed 10/8

10:00 am-4:24 pm

2 stops13h 24m

$889

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 1/1

9:29 am-10:10 am

2 stops17h 41m

Brussels Bruxelles-National

Fri 1/16

8:05 am-6:34 pm

2 stops17h 29m

$907

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Wed 3/4

1:00 pm-10:10 am

2 stops38h 10m

Brussels Bruxelles-National

Sun 3/8

2:45 pm-6:34 pm

2 stops33h 49m

$999

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 11/6

1:08 pm-10:10 am

2 stops14h 02m

Brussels Bruxelles-National

Sun 11/9

2:45 pm-11:32 pm

2 stops15h 47m

$1,049

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Tue 9/30

10:35 am-8:40 am

1 stop15h 05m

Brussels Bruxelles-National

Fri 10/3

10:45 am-5:35 pm

1 stop13h 50m

$1,957

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Wed 10/1

6:30 pm-8:40 am

1 stop31h 10m

Brussels Bruxelles-National

Sat 10/4

6:10 am-3:26 pm

2 stops16h 16m

$2,112

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Brussels from

How to get the cheapest flight ticket from Chicago Midway Airport to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Brussels Bruxelles-National Airport?

The cheapest day to depart from Chicago Midway Airport to Brussels Bruxelles-National Airport is on a Wednesday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Wednesday will often find tickets for as low as $1,098. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Chicago Midway Airport to Brussels Bruxelles-National Airport for around $1,378.

What is the cheapest time of day to depart on your flight to Brussels Bruxelles-National Airport?

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is in the evening. Flights from Chicago Midway Airport to Brussels Bruxelles-National Airport during this time can be as low as $579. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $1,186 on average. Flights to Brussels Bruxelles-National Airport from Chicago Midway Airport in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Chicago Midway Airport to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Brussels Bruxelles-National Airport (MDW to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Brussels Bruxelles-National Airport

Direct flights

None
There are no direct flights from Chicago Midway Airport to Brussels Bruxelles-National Airport. There are no popular flight routes from Chicago Midway Airport to Brussels Bruxelles-National Airport.
Search flight deals

  • How far is Chicago Midway to Brussels Bruxelles-National by plane?

    There are 4148.0 mi between Chicago Midway and Brussels Bruxelles-National. Flights usually cover this in 11h 27m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago Midway Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Chicago Midway Airport to Brussels Bruxelles-National Airport were last updated today.

  • How old do you have to be to fly from Chicago Midway Airport to Brussels Bruxelles-National Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago Midway Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Bruges
Ghent
Leuven
Charleroi
Hasselt
Spa
Namur
Aalst
Dinant
Mons
Zaventem
Waterloo
Genk
Mechelen
Francorchamps
Knokke-Heist
Tournai
Durbuy
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Brussels with flexible booking policies on momondo?

All flight searches from Chicago to Brussels on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Brussels?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Brussels.

I’m not ready to book a flight from Chicago to Brussels right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Brussels from Chicago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Brussels Bruxelles-National Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 10/18
Sat 10/25
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Brussels

Popular cities in Belgium

Popular flights according to clicks in the last 7 days on momondo
Flights to Charleroi Brussels Airportfrom $447