Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Chicago Midway Airport to Brussels from $355

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Brussels departing on 5/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago Midway Airport to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:00 am - 7:50 am
MDW
-
BRU
13h 50m
2 stops
Multiple Airlines Logo
9:30 am - 9:45 am
BRU
-
MDW
31h 15m
2 stops
$1,081Multiple Airlines
Thu, Apr 23 - Fri, May 1
Multiple Airlines Logo
8:45 am - 12:45 pm
MDW
-
BRU
21h 00m
2 stops
Multiple Airlines Logo
8:30 am - 8:50 pm
BRU
-
MDW
19h 20m
2 stops
$1,188Multiple Airlines
Tue, Sep 1 - Tue, Sep 8
KLM Logo
10:41 am - 7:40 am
MDW
-
BRU
13h 59m
1 stop
KLM Logo
9:45 am - 4:26 pm
BRU
-
MDW
13h 41m
1 stop
$1,224KLM
Sun, Apr 26 - Tue, May 5
Air France Logo
12:52 pm - 7:40 am
MDW
-
BRU
11h 48m
1 stop
Air France Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$1,226Air France
Sun, May 3 - Tue, May 12
Air France Logo
10:41 am - 7:40 am
MDW
-
BRU
13h 59m
1 stop
Air France Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$1,228Air France
Sun, May 3 - Tue, May 12
Delta Logo
12:52 pm - 7:40 am
MDW
-
BRU
11h 48m
1 stop
Delta Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$1,230Delta
Sun, May 3 - Tue, May 12
Delta Logo
12:52 pm - 7:40 am
MDW
-
BRU
11h 48m
1 stop
Delta Logo
9:45 am - 9:09 pm
BRU
-
MDW
18h 24m
1 stop
$1,236Delta
Sun, May 3 - Tue, May 12
Delta Logo
12:52 pm - 7:40 am
MDW
-
BRU
11h 48m
1 stop
Delta Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$1,237Delta
Sun, May 3 - Tue, May 12
Delta Logo
9:27 am - 7:40 am
MDW
-
BRU
15h 13m
2 stops
Delta Logo
9:45 am - 5:58 pm
BRU
-
MDW
15h 13m
2 stops
$1,241Delta
Sun, Apr 26 - Tue, May 5
Delta Logo
12:52 pm - 7:40 am
MDW
-
BRU
11h 48m
1 stop
Delta Logo
6:20 am - 4:26 pm
BRU
-
MDW
17h 06m
2 stops
$1,244Delta
Wed, Apr 29 - Wed, May 6

KLM flights from Chicago Midway Airport to Brussels Bruxelles-National Airport

Our best KLM deals on Chicago Midway Airport to Brussels Bruxelles-National Airport flight tickets
KLM
Apr 26
MDW10:41 amChicago Midway
13h 59m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 5
BRU9:45 amBrussels Bruxelles-National
13h 41m
1 stop
MDW4:26 pmChicago Midway
$1,224
KLM
May 3
MDW6:00 amChicago Midway
18h 40m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 12
BRU9:45 amBrussels Bruxelles-National
13h 27m
1 stop
MDW4:12 pmChicago Midway
$1,311
KLM
May 3
MDW6:38 pmChicago Midway
13h 02m
2 stops
BRU2:40 pmBrussels Bruxelles-National
May 12
BRU10:25 amBrussels Bruxelles-National
14h 31m
2 stops
MDW5:56 pmChicago Midway
$1,312

Delta flights from Chicago Midway Airport to Brussels Bruxelles-National Airport

Our best Delta deals on Chicago Midway Airport to Brussels Bruxelles-National Airport flight tickets
Delta
May 3
MDW12:52 pmChicago Midway
11h 48m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 12
BRU9:45 amBrussels Bruxelles-National
13h 27m
1 stop
MDW4:12 pmChicago Midway
$1,230
Delta
May 3
MDW12:52 pmChicago Midway
11h 48m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 12
BRU9:45 amBrussels Bruxelles-National
18h 24m
1 stop
MDW9:09 pmChicago Midway
$1,236
Delta
May 3
MDW12:52 pmChicago Midway
11h 48m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 12
BRU9:45 amBrussels Bruxelles-National
13h 27m
1 stop
MDW4:12 pmChicago Midway
$1,237

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 4/23

11:00 am-7:50 am

2 stops13h 50m

Brussels Bruxelles-National

Fri 5/1

9:30 am-9:45 am

2 stops31h 15m

$1,081

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Tue 9/1

8:45 am-12:45 pm

2 stops21h 00m

Brussels Bruxelles-National

Tue 9/8

8:30 am-8:50 pm

2 stops19h 20m

$1,188

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 4/26

10:41 am-7:40 am

1 stop13h 59m

Brussels Bruxelles-National

Tue 5/5

9:45 am-4:26 pm

1 stop13h 41m

$1,224
Quickest round-trip

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 5/3

12:52 pm-7:40 am

1 stop11h 48m

Brussels Bruxelles-National

Tue 5/12

9:45 am-4:12 pm

1 stop13h 27m

$1,226

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 5/3

10:41 am-7:40 am

1 stop13h 59m

Brussels Bruxelles-National

Tue 5/12

9:45 am-4:12 pm

1 stop13h 27m

$1,228

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 5/3

12:52 pm-7:40 am

1 stop11h 48m

Brussels Bruxelles-National

Tue 5/12

9:45 am-4:12 pm

1 stop13h 27m

$1,230

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 5/3

12:52 pm-7:40 am

1 stop11h 48m

Brussels Bruxelles-National

Tue 5/12

9:45 am-9:09 pm

1 stop18h 24m

$1,236

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 5/3

12:52 pm-7:40 am

1 stop11h 48m

Brussels Bruxelles-National

Tue 5/12

9:45 am-4:12 pm

1 stop13h 27m

$1,237

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 4/26

9:27 am-7:40 am

2 stops15h 13m

Brussels Bruxelles-National

Tue 5/5

9:45 am-5:58 pm

2 stops15h 13m

$1,241

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Wed 4/29

12:52 pm-7:40 am

1 stop11h 48m

Brussels Bruxelles-National

Wed 5/6

6:20 am-4:26 pm

2 stops17h 06m

$1,244

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Brussels from

How to get the cheapest flight ticket from Chicago Midway Airport to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Brussels Bruxelles-National Airport?

The cheapest day to depart from Chicago Midway Airport to Brussels Bruxelles-National Airport is on a Tuesday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Tuesday will often find tickets for as low as $1,054. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Chicago Midway Airport to Brussels Bruxelles-National Airport for around $1,385.

When to book flights from Chicago Midway Airport to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Brussels Bruxelles-National Airport (MDW to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Brussels Bruxelles-National Airport

Fastest flight time

11h 35m

Direct flights

None
The fastest flight from Chicago Midway Airport to Brussels Bruxelles-National Airport takes 11h 35m
There are no direct flights from Chicago Midway Airport to Brussels Bruxelles-National Airport. There are no popular flight routes from Chicago Midway Airport to Brussels Bruxelles-National Airport.
Search flight deals

Frequently asked questions about flying from Chicago Midway Airport to Brussels Bruxelles-National Airport

  • How far is Chicago Midway to Brussels Bruxelles-National by plane?

    There are 4148.0 mi between Chicago Midway and Brussels Bruxelles-National. Flights usually cover this in 11h 35m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago Midway Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Chicago Midway Airport to Brussels Bruxelles-National Airport were last updated today.

  • How old do you have to be to fly from Chicago Midway Airport to Brussels Bruxelles-National Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago Midway Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Ghent
Bruges
Leuven
Charleroi
Zaventem
Hasselt
Namur
Genk
Waterloo
Dinant
Durbuy
Mons
Aalst
Knokke-Heist
Spa
Mechelen
Francorchamps
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Brussels?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Brussels. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Brussels with flexible booking policies on momondo?

All flight searches from Chicago to Brussels on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to Brussels?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Brussels.

I’m not ready to book a flight from Chicago to Brussels right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Brussels from Chicago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Brussels Bruxelles-National Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 5/3
Sun 5/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Brussels

Popular cities in Belgium

Popular flights according to clicks in the last 7 days on momondo
Flights to Charleroi Brussels Airportfrom $525