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Cheap flights from Massachusetts to Panama City from $158

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Massachusetts to Panama City departing on 9/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Massachusetts to Panama City

Cheap round-trip flights

Logo
6:05 am - 12:10 amBOS-PTY
19h 05m2 stops
Logo
3:25 am - 11:57 pmPTY-BOS
19h 32m2 stops
$420
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Tue, Sep 2 - Mon, Sep 15
Logo
6:05 am - 8:19 pmBOS-PTY
15h 14m1 stop
Logo
12:03 pm - 11:57 pmPTY-BOS
10h 54m1 stop
$434
Find Deal
Tue, Sep 2 - Wed, Sep 10
Avianca Logo
9:00 am - 9:10 pmBOS-PTY
13h 10m1 stop
Avianca Logo
5:25 pm - 7:15 amPTY-BOS
12h 50m1 stop
$436Avianca
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Thu, Oct 2 - Wed, Oct 15
Avianca Logo
4:50 pm - 8:55 amBOS-PTY
17h 05m2 stops
Avianca Logo
5:25 pm - 7:15 amPTY-BOS
12h 50m1 stop
$437Avianca
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Mon, Sep 8 - Mon, Sep 15
Copa Airlines Logo
3:49 pm - 8:41 pmBOS-PTY
5h 52mnonstop
Copa Airlines Logo
4:10 pm - 10:53 pmPTY-BOS
5h 43mnonstop
$458Copa Airlines
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Thu, Oct 2 - Wed, Oct 15
Delta Logo
5:35 am - 12:50 pmBOS-PTY
8h 15m1 stop
Delta Logo
2:10 pm - 1:18 amPTY-BOS
10h 08m1 stop
$472Delta
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Mon, Sep 8 - Thu, Sep 25
Copa Airlines Logo
7:34 am - 1:33 pmBOS-PTY
5h 59mnonstop
Copa Airlines Logo
7:31 am - 1:00 pmPTY-BOS
5h 29mnonstop
$473Copa Airlines
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Thu, Nov 6 - Tue, Nov 11
American Airlines Logo
7:30 pm - 2:31 pmBOS-PTY
20h 01m2 stops
American Airlines Logo
3:15 pm - 12:34 amPTY-BOS
8h 19m1 stop
$477American Airlines
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Thu, Oct 2 - Wed, Oct 15
American Airlines Logo
6:29 pm - 2:31 pmBOS-PTY
21h 02m2 stops
American Airlines Logo
3:15 pm - 12:03 pmPTY-BOS
19h 48m2 stops
$482American Airlines
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Fri, Oct 3 - Sun, Oct 12
Delta Logo
6:07 am - 12:55 pmALB-PTY
7h 48m1 stop
Delta Logo
2:10 pm - 11:33 pmPTY-ALB
8h 23m1 stop
$517Delta
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Wed, Sep 24 - Wed, Oct 1

United Airlines flights from Massachusetts to Panama City

Our best United Airlines deals on Massachusetts to Panama City flight tickets
United Airlines
Dec 14
ALB6:30 pmAlbany Intl
22h 37m
2 stops
PTY5:07 pmPanama City Tocumen Intl
Dec 27
PTY4:41 pmPanama City Tocumen Intl
21h 55m
2 stops
ALB2:36 pmAlbany Intl
$515
Find similar
United Airlines
Sep 24
ALB6:00 amAlbany Intl
13h 37m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Oct 1
PTY10:00 amPanama City Tocumen Intl
23h 46m
2 stops
ALB10:46 amAlbany Intl
$522
Find similar
United Airlines
Oct 2
BDL6:00 amHartford Bradley Intl
13h 37m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Oct 9
PTY3:30 pmPanama City Tocumen Intl
25h 02m
2 stops
BDL5:32 pmHartford Bradley Intl
$536
Find similar

American Airlines flights from Massachusetts to Panama City

Our best American Airlines deals on Massachusetts to Panama City flight tickets
American Airlines
Oct 2
BOS7:30 pmBoston Logan Intl
20h 01m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Oct 15
PTY3:15 pmPanama City Tocumen Intl
8h 19m
1 stop
BOS12:34 amBoston Logan Intl
$477
Find similar
American Airlines
Oct 3
BOS6:29 pmBoston Logan Intl
21h 02m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Oct 12
PTY3:15 pmPanama City Tocumen Intl
19h 48m
2 stops
BOS12:03 pmBoston Logan Intl
$482
Find similar
American Airlines
Oct 9
BOS4:30 pmBoston Logan Intl
22h 33m
1 stop
PTY2:03 pmPanama City Tocumen Intl
Oct 13
PTY3:15 pmPanama City Tocumen Intl
18h 01m
2 stops
BOS10:16 amBoston Logan Intl
$489
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momondo Fare Finder

 
Customize your flight search to find flights from Massachusetts to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from Massachusetts to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Tue 9/2

6:05 am-12:10 am

2 stops19h 05m

Panama City Tocumen Intl

Mon 9/15

3:25 am-11:57 pm

2 stops19h 32m

$420

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Tue 9/2

6:05 am-8:19 pm

1 stop15h 14m

Panama City Tocumen Intl

Wed 9/10

12:03 pm-11:57 pm

1 stop10h 54m

$434

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Thu 10/2

9:00 am-9:10 pm

1 stop13h 10m

Panama City Tocumen Intl

Wed 10/15

5:25 pm-7:15 am

1 stop12h 50m

$436

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Mon 9/8

4:50 pm-8:55 am

2 stops17h 05m

Panama City Tocumen Intl

Mon 9/15

5:25 pm-7:15 am

1 stop12h 50m

$437

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Thu 10/2

3:49 pm-8:41 pm

Nonstop5h 52m

Panama City Tocumen Intl

Wed 10/15

4:10 pm-10:53 pm

Nonstop5h 43m

$458

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Mon 9/8

5:35 am-12:50 pm

1 stop8h 15m

Panama City Tocumen Intl

Thu 9/25

2:10 pm-1:18 am

1 stop10h 08m

$472

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Thu 11/6

7:34 am-1:33 pm

Nonstop5h 59m

Panama City Tocumen Intl

Tue 11/11

7:31 am-1:00 pm

Nonstop5h 29m

$473

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Thu 10/2

7:30 pm-2:31 pm

2 stops20h 01m

Panama City Tocumen Intl

Wed 10/15

3:15 pm-12:34 am

1 stop8h 19m

$477

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Fri 10/3

6:29 pm-2:31 pm

2 stops21h 02m

Panama City Tocumen Intl

Sun 10/12

3:15 pm-12:03 pm

2 stops19h 48m

$482

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Wed 9/24

6:07 am-12:55 pm

1 stop7h 48m

Panama City Tocumen Intl

Wed 10/1

2:10 pm-11:33 pm

1 stop8h 23m

$517

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Massachusetts to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from Massachusetts to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $472. If you’re not able to fly to Panama City in October, then November is your next best option. Flight prices from Massachusetts to Panama City during November average around $472.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $551. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $711. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Massachusetts to Panama City during this time can be as low as $503. Try not to purchase tickets in the morning because they tend to be around $654. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Massachusetts to Panama City Tocumen Intl flight route?

Fly from Boston Logan Intl to Panama City Tocumen Intl for the best Massachusetts - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Massachusetts when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $600 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Massachusetts for as low as $530 on momondo.

What cabin class options are available on Massachusetts to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Massachusetts to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Massachusetts to Panama City flights?

You could potentially save up to 74% on your flight if you consider stops on a Massachusetts to Panama City flight.

Cheap Massachusetts to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Massachusetts to Panama City

Best Price Found

$158

Fastest flight time

5h 52m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Massachusetts in the past 72 hours is $158. The best round-trip flight deal from Massachusetts to Panama City found on momondo in the last 72 hours is $420.
The fastest flight from Massachusetts to Panama City takes 5h 52m
Direct flights go from Massachusetts to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from Massachusetts to Panama City Tocumen Intl Airport?

    Prices for flights from Massachusetts to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Massachusetts to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Massachusetts to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Massachusetts to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Massachusetts to Panama City?

Best airlines flying from Massachusetts to Panama City

Compare and see reviews for airlines that fly from Massachusetts to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $313Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
AviancaPriceFrom $408Free CancellationRating
6.7
2,397 reviews
Search Avianca flights
Copa AirlinesPriceFrom $455Free CancellationRating
7.5
1,506 reviews
Search Copa Airlines flights
DeltaPriceFrom $464Free CancellationRating
8.0
7,979 reviews
Search Delta flights
United AirlinesPriceFrom $494Free CancellationRating
7.4
8,920 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Massachusetts to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Massachusetts to Panama City for you.

Can I find flights from Massachusetts to Panama City with flexible booking policies on momondo?

Flights from Massachusetts to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Massachusetts to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Massachusetts to Panama City.

I’m not ready to book a flight from Massachusetts to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Massachusetts. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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