Cheap flights from Madrid to Brussels from $65

The cheapest month to fly to Brussels Bruxelles-National Airport from Madrid is in February. Flight prices, which tend to average around $146, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Brussels Bruxelles-National Airport from Madrid during November instead. Flights to Brussels Bruxelles-National Airport in November, while not as cheap as those in February, still average around $148.

The cheapest day to depart from Madrid to Brussels Bruxelles-National Airport is on a Thursday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Thursday will often find tickets for as low as $238. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Madrid to Brussels Bruxelles-National Airport for around $330.

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is at noon. Flights from Madrid to Brussels Bruxelles-National Airport during this time can be as low as $139. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $317 on average. Flights to Brussels Bruxelles-National Airport from Madrid in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Madrid Barajas to Brussels Bruxelles-National for the best Madrid Barajas - Brussels Bruxelles-National flight prices

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Madrid when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $182 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Madrid for as low as $150 on momondo.

There are 3 cabin classes available to choose from on Madrid to Brussels Bruxelles-National Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Vueling, Brussels Airlines, and Air Europa are the most popular carriers operating from Madrid Barajas to Brussels Bruxelles-National

Ryanair, Brussels Airlines and Iberia are the top three most popular airlines that fly to Brussels Bruxelles-National Airport from Madrid according to our data. Ryanair is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Brussels Bruxelles-National Airport. Keep in mind that there are 4 different airlines that fly to Brussels Bruxelles-National Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 16% of flights between Madrid and Brussels have experienced a delay on any given week. The average delay length over the past 12 months has been 111 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, Iberia have had the least number of delays on this route over the last 12 months; with about 10% of their flights experiencing any sort of delay.

18 flights are operational daily from Madrid to Brussels Bruxelles-National Airport as of September 2026. The most popular departure time for this route is 9:00AM, with 51% of flights per day taking off at noon.

The number of flights available between Madrid and Brussels Bruxelles-National Airport is 129 per week as of September 2026. The most frequent departure day is Mon, with 25% of weekly flights leaving on this day.