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Cheap flights from Louisville to Panama City from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:05 am - 12:55 pm
SDF
-
PTY
6h 50m
1 stop
Delta Logo
2:28 pm - 11:59 pm
PTY
-
SDF
8h 31m
1 stop
$579Delta
Sun, Aug 30 - Wed, Sep 9
United Airlines Logo
6:15 am - 4:12 pm
SDF
-
PTY
10h 57m
1 stop
United Airlines Logo
7:55 am - 8:01 pm
PTY
-
SDF
11h 06m
1 stop
$581United Airlines
Fri, Jul 3 - Fri, Jul 10
United Airlines Logo
7:55 pm - 2:14 pm
SDF
-
PTY
19h 19m
2 stops
United Airlines Logo
3:30 pm - 4:37 pm
PTY
-
SDF
24h 07m
2 stops
$583United Airlines
Fri, Jul 17 - Mon, Aug 17
United Airlines Logo
9:30 am - 4:12 pm
SDF
-
PTY
7h 42m
1 stop
United Airlines Logo
10:55 pm - 1:35 pm
PTY
-
SDF
13h 40m
2 stops
$585United Airlines
Fri, Jul 3 - Fri, Jul 10
United Airlines Logo
11:04 am - 4:04 am
SDF
-
PTY
18h 00m
1 stop
United Airlines Logo
3:30 pm - 9:22 am
PTY
-
SDF
16h 52m
2 stops
$587United Airlines
Sat, Jun 20 - Sat, Jun 27
American Airlines Logo
3:54 pm - 12:14 pm
SDF
-
PTY
21h 20m
2 stops
American Airlines Logo
1:24 pm - 12:07 pm
PTY
-
SDF
21h 43m
2 stops
$588American Airlines
Sat, Jul 18 - Sun, Aug 16
United Airlines Logo
6:15 am - 6:37 pm
SDF
-
PTY
13h 22m
1 stop
United Airlines Logo
3:30 pm - 7:59 pm
PTY
-
SDF
27h 29m
1 stop
$589United Airlines
Fri, Jul 17 - Thu, Aug 13
Delta Logo
7:05 am - 1:09 pm
SDF
-
PTY
7h 04m
1 stop
Delta Logo
2:24 pm - 3:24 pm
PTY
-
SDF
24h 00m
1 stop
$591Delta
Sun, Jun 21 - Fri, Jun 26
United Airlines Logo
11:04 am - 4:04 am
SDF
-
PTY
18h 00m
1 stop
United Airlines Logo
10:55 pm - 10:54 pm
PTY
-
SDF
22h 59m
1 stop
$592United Airlines
Sat, Jun 20 - Sun, Jun 28
United Airlines Logo
11:04 am - 4:04 am
SDF
-
PTY
18h 00m
1 stop
United Airlines Logo
7:55 am - 10:15 pm
PTY
-
SDF
13h 20m
1 stop
$594United Airlines
Sat, Jun 20 - Mon, Jun 29

United Airlines flights from Louisville to Panama City

Our best United Airlines deals on Louisville to Panama City flight tickets
United Airlines
Jul 3
SDF6:15 amLouisville Intl
10h 57m
1 stop
PTY4:12 pmPanama City Tocumen Intl
Jul 10
PTY7:55 amPanama City Tocumen Intl
11h 06m
1 stop
SDF8:01 pmLouisville Intl
$581
United Airlines
Jul 17
SDF7:55 pmLouisville Intl
19h 19m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Aug 17
PTY3:30 pmPanama City Tocumen Intl
24h 07m
2 stops
SDF4:37 pmLouisville Intl
$583
United Airlines
Jul 3
SDF9:30 amLouisville Intl
7h 42m
1 stop
PTY4:12 pmPanama City Tocumen Intl
Jul 10
PTY10:55 pmPanama City Tocumen Intl
13h 40m
2 stops
SDF1:35 pmLouisville Intl
$585

Delta flights from Louisville to Panama City

Our best Delta deals on Louisville to Panama City flight tickets
Delta
Aug 30
SDF7:05 amLouisville Intl
6h 50m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Sep 9
PTY2:28 pmPanama City Tocumen Intl
8h 31m
1 stop
SDF11:59 pmLouisville Intl
$579
Delta
Jun 21
SDF7:05 amLouisville Intl
7h 04m
1 stop
PTY1:09 pmPanama City Tocumen Intl
Jun 26
PTY2:24 pmPanama City Tocumen Intl
24h 00m
1 stop
SDF3:24 pmLouisville Intl
$591
Delta
Jun 22
SDF7:05 amLouisville Intl
7h 04m
1 stop
PTY1:09 pmPanama City Tocumen Intl
Jun 26
PTY2:24 pmPanama City Tocumen Intl
26h 25m
1 stop
SDF5:49 pmLouisville Intl
$602

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sun 8/30

7:05 am-12:55 pm

1 stop6h 50m

Panama City Tocumen Intl

Wed 9/9

2:28 pm-11:59 pm

1 stop8h 31m

$579

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 7/3

6:15 am-4:12 pm

1 stop10h 57m

Panama City Tocumen Intl

Fri 7/10

7:55 am-8:01 pm

1 stop11h 06m

$581

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 7/17

7:55 pm-2:14 pm

2 stops19h 19m

Panama City Tocumen Intl

Mon 8/17

3:30 pm-4:37 pm

2 stops24h 07m

$583

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 7/3

9:30 am-4:12 pm

1 stop7h 42m

Panama City Tocumen Intl

Fri 7/10

10:55 pm-1:35 pm

2 stops13h 40m

$585

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 6/20

11:04 am-4:04 am

1 stop18h 00m

Panama City Tocumen Intl

Sat 6/27

3:30 pm-9:22 am

2 stops16h 52m

$587

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 7/18

3:54 pm-12:14 pm

2 stops21h 20m

Panama City Tocumen Intl

Sun 8/16

1:24 pm-12:07 pm

2 stops21h 43m

$588

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 7/17

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Thu 8/13

3:30 pm-7:59 pm

1 stop27h 29m

$589

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sun 6/21

7:05 am-1:09 pm

1 stop7h 04m

Panama City Tocumen Intl

Fri 6/26

2:24 pm-3:24 pm

1 stop24h 00m

$591

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 6/20

11:04 am-4:04 am

1 stop18h 00m

Panama City Tocumen Intl

Sun 6/28

10:55 pm-10:54 pm

1 stop22h 59m

$592

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 6/20

11:04 am-4:04 am

1 stop18h 00m

Panama City Tocumen Intl

Mon 6/29

7:55 am-10:15 pm

1 stop13h 20m

$594

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Panama City?

What is the cheapest month to fly to Panama City?

In general, February is the cheapest month to fly from Louisville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $430. If you’re not able to fly to Panama City in February, then January is your next best option. Flight prices from Louisville to Panama City during January average around $493.

Can stopping save me money on Louisville to Panama City flights?

You could potentially save up to 28% on your flight if you consider stops on a Louisville to Panama City flight.

When to book flights from Louisville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City (SDF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City

Fastest flight time

6h 56m

Direct flights

None
The fastest flight from Louisville to Panama City takes 6h 56m
There are no direct flights from Louisville to Panama City. There are no popular flight routes from Louisville to Panama City.
Search flight deals

Frequently asked questions about flying from Louisville to Panama City

  • How far is Louisville Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2057.4 mi away from Louisville Intl. 6h 56m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City?

Best airlines flying from Louisville to Panama City

Compare and see reviews for airlines that fly from Louisville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $430Free CancellationRating
7.9
8,449 reviews
Search Delta flights
United AirlinesPriceFrom $430Free CancellationRating
7.4
9,751 reviews
Search United Airlines flights
American AirlinesPriceFrom $434Free CancellationRating
7.1
11,644 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

All flight searches from Louisville to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Panama City.

I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?

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