Cheap flights from Louisville to Panama City from $195

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 3/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:00 am - 4:12 pm
SDF
-
PTY
11h 12m
1 stop
United Airlines Logo
7:55 am - 9:44 pm
PTY
-
SDF
12h 49m
1 stop
$453United Airlines
Tue, Apr 21 - Sat, Apr 25
United Airlines Logo
6:00 am - 5:07 pm
SDF
-
PTY
11h 07m
1 stop
United Airlines Logo
11:35 am - 9:46 pm
PTY
-
SDF
10h 11m
1 stop
$455United Airlines
Mon, Feb 23 - Wed, Mar 4
Multiple Airlines Logo
6:00 am - 8:02 pm
SDF
-
PTY
14h 02m
1 stop
Multiple Airlines Logo
9:30 am - 11:59 pm
PTY
-
SDF
13h 29m
1 stop
$457Multiple Airlines
Thu, Mar 5 - Mon, Mar 9
United Airlines Logo
5:54 pm - 5:07 pm
SDF
-
PTY
23h 13m
2 stops
United Airlines Logo
4:41 pm - 1:17 pm
PTY
-
SDF
20h 36m
2 stops
$459United Airlines
Mon, Feb 23 - Wed, Mar 4
Multiple Airlines Logo
7:05 am - 8:02 pm
SDF
-
PTY
12h 57m
2 stops
Multiple Airlines Logo
9:30 am - 11:59 pm
PTY
-
SDF
13h 29m
1 stop
$461Multiple Airlines
Thu, Mar 5 - Mon, Mar 9
United Airlines Logo
6:00 am - 6:37 pm
SDF
-
PTY
13h 37m
1 stop
United Airlines Logo
3:30 pm - 9:59 pm
PTY
-
SDF
29h 29m
1 stop
$464United Airlines
Mon, Mar 30 - Mon, Apr 6
United Airlines Logo
5:43 pm - 2:14 pm
SDF
-
PTY
21h 31m
2 stops
United Airlines Logo
3:30 pm - 9:59 pm
PTY
-
SDF
29h 29m
1 stop
$468United Airlines
Mon, Mar 30 - Mon, Apr 6
United Airlines Logo
6:00 am - 2:14 pm
SDF
-
PTY
9h 14m
1 stop
United Airlines Logo
7:55 am - 8:00 pm
PTY
-
SDF
11h 05m
1 stop
$469United Airlines
Sat, Apr 18 - Sat, Apr 25
United Airlines Logo
5:00 am - 7:31 pm
SDF
-
PTY
15h 31m
2 stops
United Airlines Logo
10:00 am - 11:46 pm
PTY
-
SDF
12h 46m
2 stops
$473United Airlines
Sat, Apr 18 - Sat, Apr 25
United Airlines Logo
6:00 am - 7:38 pm
SDF
-
PTY
13h 38m
1 stop
United Airlines Logo
10:00 am - 7:55 pm
PTY
-
SDF
9h 55m
1 stop
$475United Airlines
Tue, Feb 24 - Fri, Feb 27

United Airlines flights from Louisville to Panama City

Our best United Airlines deals on Louisville to Panama City flight tickets
United Airlines
Apr 21
SDF7:20 amLouisville Intl
13h 11m
2 stops
PTY7:31 pmPanama City Tocumen Intl
Apr 25
PTY10:00 amPanama City Tocumen Intl
9h 00m
1 stop
SDF8:00 pmLouisville Intl
$453
United Airlines
Feb 23
SDF6:00 amLouisville Intl
11h 07m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Mar 4
PTY11:35 amPanama City Tocumen Intl
10h 11m
1 stop
SDF9:46 pmLouisville Intl
$455
United Airlines
Feb 23
SDF5:54 pmLouisville Intl
23h 13m
2 stops
PTY5:07 pmPanama City Tocumen Intl
Mar 4
PTY4:41 pmPanama City Tocumen Intl
20h 36m
2 stops
SDF1:17 pmLouisville Intl
$459

American Airlines flights from Louisville to Panama City

Our best American Airlines deals on Louisville to Panama City flight tickets
American Airlines
Mar 12
SDF6:07 amLouisville Intl
9h 13m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Mar 17
PTY3:10 pmPanama City Tocumen Intl
7h 49m
1 stop
SDF11:59 pmLouisville Intl
$585
American Airlines
Mar 12
SDF6:07 amLouisville Intl
7h 33m
1 stop
PTY12:40 pmPanama City Tocumen Intl
Mar 17
PTY1:40 pmPanama City Tocumen Intl
18h 10m
2 stops
SDF8:50 amLouisville Intl
$589
American Airlines
Feb 22
SDF8:02 pmLouisville Intl
19h 13m
2 stops
PTY3:15 pmPanama City Tocumen Intl
Mar 1
PTY4:05 pmPanama City Tocumen Intl
22h 58m
2 stops
SDF3:03 pmLouisville Intl
$614

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 16, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 4/21

6:00 am-4:12 pm

1 stop11h 12m

Panama City Tocumen Intl

Sat 4/25

7:55 am-9:44 pm

1 stop12h 49m

$453

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 2/23

6:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Wed 3/4

11:35 am-9:46 pm

1 stop10h 11m

$455

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 3/5

6:00 am-8:02 pm

1 stop14h 02m

Panama City Tocumen Intl

Mon 3/9

9:30 am-11:59 pm

1 stop13h 29m

$457

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 2/23

5:54 pm-5:07 pm

2 stops23h 13m

Panama City Tocumen Intl

Wed 3/4

4:41 pm-1:17 pm

2 stops20h 36m

$459

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 3/5

7:05 am-8:02 pm

2 stops12h 57m

Panama City Tocumen Intl

Mon 3/9

9:30 am-11:59 pm

1 stop13h 29m

$461

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 3/30

6:00 am-6:37 pm

1 stop13h 37m

Panama City Tocumen Intl

Mon 4/6

3:30 pm-9:59 pm

1 stop29h 29m

$464

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 3/30

5:43 pm-2:14 pm

2 stops21h 31m

Panama City Tocumen Intl

Mon 4/6

3:30 pm-9:59 pm

1 stop29h 29m

$468

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 4/18

6:00 am-2:14 pm

1 stop9h 14m

Panama City Tocumen Intl

Sat 4/25

7:55 am-8:00 pm

1 stop11h 05m

$469

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 4/18

5:00 am-7:31 pm

2 stops15h 31m

Panama City Tocumen Intl

Sat 4/25

10:00 am-11:46 pm

2 stops12h 46m

$473

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 2/24

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Fri 2/27

10:00 am-7:55 pm

1 stop9h 55m

$475

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Louisville Intl to Panama City Tocumen Intl?

Delta, Copa Airlines, and LATAM Airlines are the most popular carriers operating from Louisville Intl to Panama City Tocumen Intl

What airlines fly to Panama City?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama City from Louisville according to our data. United Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

When to book flights from Louisville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City (SDF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City

Fastest flight time

11h 07m

Direct flights

None
The fastest flight from Louisville to Panama City takes 11h 07m
There are no direct flights from Louisville to Panama City. There are no popular flight routes from Louisville to Panama City.
  • How far is Louisville Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2057.4 mi away from Louisville Intl. 11h 07m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City?

Best airlines flying from Louisville to Panama City

Compare and see reviews for airlines that fly from Louisville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $351Free CancellationRating
7.4
9,299 reviews
Search United Airlines flights
American AirlinesPriceFrom $410Free CancellationRating
7.2
11,294 reviews
Search American Airlines flights
DeltaPriceFrom $430Free CancellationRating
7.9
8,204 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

All flight searches from Louisville to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Panama City.

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1 adult
Wed 3/18
Wed 3/25

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