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Cheap flights from Louisville to Panama City from $423

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

United Airlines Logo
7:15 am - 6:37 pmSDF-PTY
12h 22m1 stop
United Airlines Logo
10:00 am - 10:00 pmPTY-SDF
11h 00m1 stop
$423United Airlines
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Mon, Aug 18 - Mon, Aug 25
United Airlines Logo
7:20 pm - 2:14 pmSDF-PTY
19h 54m2 stops
United Airlines Logo
10:00 am - 10:00 pmPTY-SDF
11h 00m1 stop
$428United Airlines
Find Deal
Mon, Aug 18 - Mon, Aug 25
Delta Logo
6:00 am - 12:55 pmSDF-PTY
7h 55m1 stop
Delta Logo
2:10 pm - 11:52 pmPTY-SDF
8h 42m1 stop
$430Delta
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Sat, Sep 27 - Wed, Oct 1
United Airlines Logo
7:20 pm - 6:37 pmSDF-PTY
24h 17m2 stops
United Airlines Logo
3:30 pm - 1:21 pmPTY-SDF
20h 51m2 stops
$435United Airlines
Find Deal
Sat, Sep 27 - Wed, Oct 1
American Airlines Logo
6:44 pm - 2:31 pmSDF-PTY
20h 47m2 stops
American Airlines Logo
3:31 pm - 2:03 pmPTY-SDF
21h 32m2 stops
$437American Airlines
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Fri, Sep 12 - Fri, Sep 19
United Airlines Logo
9:40 am - 6:37 pmSDF-PTY
9h 57m1 stop
United Airlines Logo
10:00 am - 10:00 pmPTY-SDF
11h 00m1 stop
$439United Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
Logo
8:30 am - 9:10 pmSDF-PTY
13h 40m2 stops
Logo
3:20 am - 10:28 pmPTY-SDF
18h 08m2 stops
$445
Find Deal
Fri, Sep 12 - Thu, Sep 18
Delta Logo
6:00 am - 1:52 pmSDF-PTY
7h 52m1 stop
Delta Logo
3:17 pm - 11:56 pmPTY-SDF
8h 39m1 stop
$462Delta
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Mon, Dec 1 - Wed, Dec 17
American Airlines Logo
6:39 pm - 2:30 pmSDF-PTY
20h 51m2 stops
American Airlines Logo
3:30 pm - 2:44 pmPTY-SDF
22h 14m2 stops
$479American Airlines
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Fri, Aug 15 - Sun, Aug 31
Logo
9:47 am - 8:55 amSDF-PTY
24h 08m2 stops
Logo
3:20 am - 9:19 amPTY-SDF
28h 59m3 stops
$490
Find Deal
Fri, Sep 12 - Thu, Sep 18

United Airlines flights from Louisville to Panama City

Our best United Airlines deals on Louisville to Panama City flight tickets
United Airlines
Aug 18
SDF7:15 amLouisville Intl
12h 22m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 25
PTY10:00 amPanama City Tocumen Intl
11h 00m
1 stop
SDF10:00 pmLouisville Intl
$423
Find similar
United Airlines
Aug 18
SDF7:20 pmLouisville Intl
19h 54m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Aug 25
PTY10:00 amPanama City Tocumen Intl
11h 00m
1 stop
SDF10:00 pmLouisville Intl
$428
Find similar
United Airlines
Sep 27
SDF7:20 pmLouisville Intl
24h 17m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Oct 1
PTY3:30 pmPanama City Tocumen Intl
20h 51m
2 stops
SDF1:21 pmLouisville Intl
$435
Find similar

American Airlines flights from Louisville to Panama City

Our best American Airlines deals on Louisville to Panama City flight tickets
American Airlines
Aug 8
SDF6:14 amLouisville Intl
9h 16m
1 stop
PTY2:30 pmPanama City Tocumen Intl
Aug 15
PTY3:30 pmPanama City Tocumen Intl
19h 12m
2 stops
SDF11:42 amLouisville Intl
$428
Find similar
American Airlines
Sep 12
SDF6:44 pmLouisville Intl
20h 47m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Sep 19
PTY3:31 pmPanama City Tocumen Intl
21h 32m
2 stops
SDF2:03 pmLouisville Intl
$437
Find similar
American Airlines
Aug 8
SDF6:39 pmLouisville Intl
20h 51m
2 stops
PTY2:30 pmPanama City Tocumen Intl
Aug 15
PTY3:30 pmPanama City Tocumen Intl
19h 12m
2 stops
SDF11:42 amLouisville Intl
$448
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 8/18

7:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Mon 8/25

10:00 am-10:00 pm

1 stop11h 00m

$423

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 8/18

7:20 pm-2:14 pm

2 stops19h 54m

Panama City Tocumen Intl

Mon 8/25

10:00 am-10:00 pm

1 stop11h 00m

$428

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 9/27

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 10/1

2:10 pm-11:52 pm

1 stop8h 42m

$430

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 9/27

7:20 pm-6:37 pm

2 stops24h 17m

Panama City Tocumen Intl

Wed 10/1

3:30 pm-1:21 pm

2 stops20h 51m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 9/12

6:44 pm-2:31 pm

2 stops20h 47m

Panama City Tocumen Intl

Fri 9/19

3:31 pm-2:03 pm

2 stops21h 32m

$437

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 9/13

9:40 am-6:37 pm

1 stop9h 57m

Panama City Tocumen Intl

Sat 9/20

10:00 am-10:00 pm

1 stop11h 00m

$439

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 9/12

8:30 am-9:10 pm

2 stops13h 40m

Panama City Tocumen Intl

Thu 9/18

3:20 am-10:28 pm

2 stops18h 08m

$445

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 12/1

6:00 am-1:52 pm

1 stop7h 52m

Panama City Tocumen Intl

Wed 12/17

3:17 pm-11:56 pm

1 stop8h 39m

$462

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 8/15

6:39 pm-2:30 pm

2 stops20h 51m

Panama City Tocumen Intl

Sun 8/31

3:30 pm-2:44 pm

2 stops22h 14m

$479

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 9/12

9:47 am-8:55 am

2 stops24h 08m

Panama City Tocumen Intl

Thu 9/18

3:20 am-9:19 am

3 stops28h 59m

$490

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Louisville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $416. If you’re not able to fly to Panama City in September, then May is your next best option. Flight prices from Louisville to Panama City during May average around $423.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Monday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $395. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $551. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Louisville to Panama City during this time can be as low as $365. Try not to purchase tickets in the morning because they tend to be around $474. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Louisville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City (SDF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City

Best Price Found

$423

Fastest flight time

7h 37m

Direct flights

None

Airports in Panama City

1 airport
The best flight deal from Louisville to Panama City found on momondo in the last 72 hours is $423
The fastest flight from Louisville to Panama City takes 7h 37m
There are no direct flights from Louisville to Panama City. Popular non-direct route for this connection is Louisville Intl Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is Louisville Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2057.4 mi away from Louisville Intl. 7h 37m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City?

Best airlines flying from Louisville to Panama City

Compare and see reviews for airlines that fly from Louisville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $338Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $351Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
DeltaPriceFrom $382Free CancellationRating
8.0
7,981 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

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Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

All flight searches from Louisville to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Panama City.

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