Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Louisville to Panama City from $424

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 2/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Louisville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:15 am - 7:38 pm
SDF
-
PTY
10h 23m1 stop
United Airlines Logo
11:35 am - 9:59 pm
PTY
-
SDF
10h 24m1 stop
$424United Airlines
Mon, Feb 2 - Thu, Feb 5
United Airlines Logo
6:12 pm - 2:45 pm
SDF
-
PTY
20h 33m2 stops
United Airlines Logo
11:35 am - 9:59 pm
PTY
-
SDF
10h 24m1 stop
$428United Airlines
Mon, Feb 2 - Thu, Feb 5
United Airlines Logo
10:45 am - 8:02 pm
SDF
-
PTY
9h 17m1 stop
United Airlines Logo
11:35 am - 9:46 pm
PTY
-
SDF
10h 11m1 stop
$431United Airlines
Tue, Feb 17 - Fri, Feb 27
United Airlines Logo
9:00 am - 4:10 am
SDF
-
PTY
20h 10m2 stops
United Airlines Logo
3:41 pm - 1:17 pm
PTY
-
SDF
20h 36m2 stops
$435United Airlines
Sat, Mar 14 - Thu, Mar 19
United Airlines Logo
9:15 am - 2:45 pm
SDF
-
PTY
29h 30m1 stop
United Airlines Logo
8:55 am - 9:46 pm
PTY
-
SDF
12h 51m1 stop
$439United Airlines
Sat, Feb 14 - Thu, Feb 19
United Airlines Logo
5:35 am - 7:38 pm
SDF
-
PTY
14h 03m2 stops
United Airlines Logo
3:41 pm - 1:17 pm
PTY
-
SDF
20h 36m2 stops
$442United Airlines
Fri, Mar 6 - Fri, Mar 13
United Airlines Logo
6:00 am - 5:07 pm
SDF
-
PTY
11h 07m1 stop
United Airlines Logo
10:00 am - 7:31 pm
PTY
-
SDF
9h 31m1 stop
$444United Airlines
Fri, Jan 9 - Thu, Feb 5
United Airlines Logo
6:00 am - 7:38 pm
SDF
-
PTY
13h 38m1 stop
United Airlines Logo
3:41 pm - 7:51 pm
PTY
-
SDF
27h 10m1 stop
$446United Airlines
Fri, Mar 6 - Fri, Mar 13
American Airlines Logo
4:32 pm - 1:27 pm
SDF
-
PTY
20h 55m2 stops
American Airlines Logo
4:50 pm - 12:25 pm
PTY
-
SDF
19h 35m2 stops
$448American Airlines
Fri, Jan 9 - Thu, Feb 5
American Airlines Logo
7:57 pm - 12:40 pm
SDF
-
PTY
17h 43m2 stops
American Airlines Logo
1:44 pm - 11:59 pm
PTY
-
SDF
9h 15m1 stop
$473American Airlines
Fri, Mar 20 - Thu, Apr 2

United Airlines flights from Louisville to Panama City

Our best United Airlines deals on Louisville to Panama City flight tickets
United Airlines
Feb 2
SDF9:15 amLouisville Intl
10h 23m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 5
PTY11:35 amPanama City Tocumen Intl
10h 24m
1 stop
SDF9:59 pmLouisville Intl
$424
Find similar
United Airlines
Feb 2
SDF6:12 pmLouisville Intl
20h 33m
2 stops
PTY2:45 pmPanama City Tocumen Intl
Feb 5
PTY11:35 amPanama City Tocumen Intl
10h 24m
1 stop
SDF9:59 pmLouisville Intl
$428
Find similar
United Airlines
Feb 17
SDF10:45 amLouisville Intl
9h 17m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Feb 27
PTY11:35 amPanama City Tocumen Intl
10h 11m
1 stop
SDF9:46 pmLouisville Intl
$431
Find similar

American Airlines flights from Louisville to Panama City

Our best American Airlines deals on Louisville to Panama City flight tickets
American Airlines
Jan 9
SDF4:32 pmLouisville Intl
20h 55m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 5
PTY4:50 pmPanama City Tocumen Intl
19h 35m
2 stops
SDF12:25 pmLouisville Intl
$448
Find similar
American Airlines
Mar 20
SDF7:57 pmLouisville Intl
17h 43m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Apr 2
PTY1:44 pmPanama City Tocumen Intl
9h 15m
1 stop
SDF11:59 pmLouisville Intl
$473
Find similar
American Airlines
Feb 26
SDF8:13 pmLouisville Intl
19h 02m
2 stops
PTY3:15 pmPanama City Tocumen Intl
Mar 1
PTY2:50 pmPanama City Tocumen Intl
20h 08m
2 stops
SDF10:58 amLouisville Intl
$478
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 2/2

9:15 am-7:38 pm

1 stop10h 23m

Panama City Tocumen Intl

Thu 2/5

11:35 am-9:59 pm

1 stop10h 24m

$424

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 2/2

6:12 pm-2:45 pm

2 stops20h 33m

Panama City Tocumen Intl

Thu 2/5

11:35 am-9:59 pm

1 stop10h 24m

$428

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 2/17

10:45 am-8:02 pm

1 stop9h 17m

Panama City Tocumen Intl

Fri 2/27

11:35 am-9:46 pm

1 stop10h 11m

$431

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 3/14

9:00 am-4:10 am

2 stops20h 10m

Panama City Tocumen Intl

Thu 3/19

3:41 pm-1:17 pm

2 stops20h 36m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Sat 2/14

9:15 am-2:45 pm

1 stop29h 30m

Panama City Tocumen Intl

Thu 2/19

8:55 am-9:46 pm

1 stop12h 51m

$439

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 3/6

5:35 am-7:38 pm

2 stops14h 03m

Panama City Tocumen Intl

Fri 3/13

3:41 pm-1:17 pm

2 stops20h 36m

$442

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 1/9

6:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Thu 2/5

10:00 am-7:31 pm

1 stop9h 31m

$444

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 3/6

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Fri 3/13

3:41 pm-7:51 pm

1 stop27h 10m

$446

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 1/9

4:32 pm-1:27 pm

2 stops20h 55m

Panama City Tocumen Intl

Thu 2/5

4:50 pm-12:25 pm

2 stops19h 35m

$448

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 3/20

7:57 pm-12:40 pm

2 stops17h 43m

Panama City Tocumen Intl

Thu 4/2

1:44 pm-11:59 pm

1 stop9h 15m

$473

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Louisville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $410. If you’re not able to fly to Panama City in September, then May is your next best option. Flight prices from Louisville to Panama City during May average around $423.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Monday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $395. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $551. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Louisville to Panama City during this time can be as low as $365. Try not to purchase tickets in the morning because they tend to be around $474. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Louisville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City (SDF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City

Fastest flight time

7h 52m

Direct flights

None
The fastest flight from Louisville to Panama City takes 7h 52m
There are no direct flights from Louisville to Panama City. There are no popular flight routes from Louisville to Panama City.
Search flight deals

  • How far is Louisville Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2057.4 mi away from Louisville Intl. 7h 52m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City?

Best airlines flying from Louisville to Panama City

Compare and see reviews for airlines that fly from Louisville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $381Free CancellationRating
7.4
9,105 reviews
Search United Airlines flights
American AirlinesPriceFrom $410Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
DeltaPriceFrom $430Free CancellationRating
7.9
8,014 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

All flight searches from Louisville to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Panama City.

I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 1/22
Thu 1/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama