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Cheap flights from Louisville to Panama City from $242

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 5/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Louisville to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:56 pm - 2:14 pm
SDF
-
PTY
19h 18m
2 stops
United Airlines Logo
10:55 pm - 7:02 pm
PTY
-
SDF
19h 07m
2 stops
$540United Airlines
Mon, May 18 - Fri, Jun 12
United Airlines Logo
7:56 pm - 2:14 pm
SDF
-
PTY
19h 18m
2 stops
United Airlines Logo
7:55 am - 10:15 pm
PTY
-
SDF
13h 20m
1 stop
$543United Airlines
Mon, May 18 - Fri, Jun 12
United Airlines Logo
9:15 am - 6:37 pm
SDF
-
PTY
10h 22m
1 stop
United Airlines Logo
3:30 pm - 8:00 pm
PTY
-
SDF
27h 30m
1 stop
$545United Airlines
Tue, Apr 21 - Sat, Apr 25
United Airlines Logo
11:45 am - 7:31 pm
SDF
-
PTY
8h 46m
1 stop
United Airlines Logo
7:55 am - 10:15 pm
PTY
-
SDF
13h 20m
1 stop
$549United Airlines
Fri, May 29 - Mon, Jun 1
Delta Logo
7:08 am - 12:50 pm
SDF
-
PTY
6h 42m
1 stop
Delta Logo
2:15 pm - 10:36 pm
PTY
-
SDF
7h 21m
1 stop
$551Delta
Fri, May 15 - Fri, May 22
United Airlines Logo
6:00 am - 4:12 pm
SDF
-
PTY
11h 12m
1 stop
United Airlines Logo
7:55 am - 8:01 pm
PTY
-
SDF
11h 06m
1 stop
$552United Airlines
Thu, May 14 - Thu, May 21
United Airlines Logo
11:45 am - 7:31 pm
SDF
-
PTY
8h 46m
1 stop
United Airlines Logo
3:30 pm - 9:02 am
PTY
-
SDF
16h 32m
2 stops
$553United Airlines
Fri, May 29 - Mon, Jun 1
Delta Logo
7:08 am - 12:50 pm
SDF
-
PTY
6h 42m
1 stop
Delta Logo
2:15 pm - 10:36 pm
PTY
-
SDF
7h 21m
1 stop
$554Delta
Fri, May 8 - Mon, May 11
United Airlines Logo
6:00 am - 2:14 pm
SDF
-
PTY
9h 14m
1 stop
United Airlines Logo
7:55 am - 8:00 pm
PTY
-
SDF
11h 05m
1 stop
$555United Airlines
Thu, Apr 16 - Tue, Apr 21
United Airlines Logo
7:56 pm - 4:12 pm
SDF
-
PTY
21h 16m
2 stops
United Airlines Logo
7:55 am - 10:15 pm
PTY
-
SDF
13h 20m
1 stop
$556United Airlines
Mon, May 18 - Fri, Jun 12

United Airlines flights from Louisville to Panama City

Our best United Airlines deals on Louisville to Panama City flight tickets
United Airlines
May 18
SDF7:56 pmLouisville Intl
19h 18m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Jun 12
PTY10:55 pmPanama City Tocumen Intl
19h 07m
2 stops
SDF7:02 pmLouisville Intl
$540
United Airlines
May 18
SDF7:56 pmLouisville Intl
19h 18m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Jun 12
PTY7:55 amPanama City Tocumen Intl
13h 20m
1 stop
SDF10:15 pmLouisville Intl
$543
United Airlines
May 29
SDF11:45 amLouisville Intl
8h 46m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Jun 1
PTY7:55 amPanama City Tocumen Intl
13h 20m
1 stop
SDF10:15 pmLouisville Intl
$549

Delta flights from Louisville to Panama City

Our best Delta deals on Louisville to Panama City flight tickets
Delta
May 8
SDF7:08 amLouisville Intl
6h 42m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 11
PTY2:15 pmPanama City Tocumen Intl
7h 21m
1 stop
SDF10:36 pmLouisville Intl
$554
Delta
Apr 19
SDF7:54 pmLouisville Intl
18h 08m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 22
PTY2:27 pmPanama City Tocumen Intl
8h 32m
1 stop
SDF11:59 pmLouisville Intl
$562
Delta
Apr 21
SDF6:00 amLouisville Intl
8h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 25
PTY2:27 pmPanama City Tocumen Intl
8h 32m
1 stop
SDF11:59 pmLouisville Intl
$618

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 5/18

7:56 pm-2:14 pm

2 stops19h 18m

Panama City Tocumen Intl

Fri 6/12

10:55 pm-7:02 pm

2 stops19h 07m

$540

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 5/18

7:56 pm-2:14 pm

2 stops19h 18m

Panama City Tocumen Intl

Fri 6/12

7:55 am-10:15 pm

1 stop13h 20m

$543

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Tue 4/21

9:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Sat 4/25

3:30 pm-8:00 pm

1 stop27h 30m

$545

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 5/29

11:45 am-7:31 pm

1 stop8h 46m

Panama City Tocumen Intl

Mon 6/1

7:55 am-10:15 pm

1 stop13h 20m

$549
Quickest round-trip

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 5/15

7:08 am-12:50 pm

1 stop6h 42m

Panama City Tocumen Intl

Fri 5/22

2:15 pm-10:36 pm

1 stop7h 21m

$551

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 5/14

6:00 am-4:12 pm

1 stop11h 12m

Panama City Tocumen Intl

Thu 5/21

7:55 am-8:01 pm

1 stop11h 06m

$552

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 5/29

11:45 am-7:31 pm

1 stop8h 46m

Panama City Tocumen Intl

Mon 6/1

3:30 pm-9:02 am

2 stops16h 32m

$553

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Fri 5/8

7:08 am-12:50 pm

1 stop6h 42m

Panama City Tocumen Intl

Mon 5/11

2:15 pm-10:36 pm

1 stop7h 21m

$554

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Thu 4/16

6:00 am-2:14 pm

1 stop9h 14m

Panama City Tocumen Intl

Tue 4/21

7:55 am-8:00 pm

1 stop11h 05m

$555

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

Mon 5/18

7:56 pm-4:12 pm

2 stops21h 16m

Panama City Tocumen Intl

Fri 6/12

7:55 am-10:15 pm

1 stop13h 20m

$556

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Panama City?

What is the cheapest month to fly to Panama City?

In general, February is the cheapest month to fly from Louisville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $437. If you’re not able to fly to Panama City in February, then January is your next best option. Flight prices from Louisville to Panama City during January average around $493.

Can stopping save me money on Louisville to Panama City flights?

You could potentially save up to 10% on your flight if you consider stops on a Louisville to Panama City flight.

When to book flights from Louisville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City (SDF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City

Fastest flight time

7h 57m

Direct flights

None
The fastest flight from Louisville to Panama City takes 7h 57m
There are no direct flights from Louisville to Panama City. There are no popular flight routes from Louisville to Panama City.
Search flight deals

Frequently asked questions about flying from Louisville to Panama City

  • How far is Louisville Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2057.4 mi away from Louisville Intl. 7h 57m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City?

Best airlines flying from Louisville to Panama City

Compare and see reviews for airlines that fly from Louisville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $423Free CancellationRating
7.4
9,533 reviews
Search United Airlines flights
DeltaPriceFrom $430Free CancellationRating
7.9
8,370 reviews
Search Delta flights
American AirlinesPriceFrom $434Free CancellationRating
7.1
11,549 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

All flight searches from Louisville to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Panama City.

I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?

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