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Cheap flights from Louisville to Panama City from $424

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 3/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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American Airlines Logo
6:31 am - 2:20 pmSDF-PTY
8h 49m1 stop
American Airlines Logo
1:50 pm - 12:14 amPTY-SDF
9h 24m1 stop
$424American Airlines
Find Deal
ven., mars 20 - mer., avr. 1
United Airlines Logo
9:31 am - 7:38 pmSDF-PTY
10h 07m1 stop
United Airlines Logo
4:41 pm - 11:32 amPTY-SDF
18h 51m2 stops
$428United Airlines
Find Deal
jeu., déc. 4 - jeu., déc. 11
Delta Logo
7:00 am - 12:55 pmSDF-PTY
6h 55m1 stop
Delta Logo
2:20 pm - 11:57 pmPTY-SDF
8h 37m1 stop
$431Delta
Find Deal
sam., mai 2 - mar., mai 5
United Airlines Logo
7:10 am - 7:38 pmSDF-PTY
12h 28m1 stop
United Airlines Logo
4:41 pm - 7:54 pmPTY-SDF
27h 13m1 stop
$432United Airlines
Find Deal
jeu., déc. 4 - jeu., déc. 11
United Airlines Logo
7:10 am - 7:38 pmSDF-PTY
12h 28m1 stop
United Airlines Logo
8:55 am - 9:57 pmPTY-SDF
13h 02m1 stop
$433United Airlines
Find Deal
mer., déc. 3 - dim., déc. 7
United Airlines Logo
7:30 am - 6:37 pmSDF-PTY
12h 07m2 stops
United Airlines Logo
7:55 am - 10:09 pmPTY-SDF
13h 14m2 stops
$435United Airlines
Find Deal
sam., mai 2 - mar., mai 5
United Airlines Logo
7:00 am - 7:38 pmSDF-PTY
12h 38m2 stops
United Airlines Logo
8:55 am - 10:29 pmPTY-SDF
13h 34m2 stops
$437United Airlines
Find Deal
mer., déc. 3 - dim., déc. 7
United Airlines Logo
6:00 am - 5:07 pmSDF-PTY
11h 07m1 stop
United Airlines Logo
11:35 am - 9:30 pmPTY-SDF
8h 55m1 stop
$438United Airlines
Find Deal
ven., mars 6 - ven., mars 13
American Airlines Logo
6:32 pm - 1:27 pmSDF-PTY
18h 55m2 stops
American Airlines Logo
4:50 pm - 10:02 amPTY-SDF
17h 12m2 stops
$440American Airlines
Find Deal
jeu., janv. 15 - dim., janv. 18
Delta Logo
6:00 am - 2:12 pmSDF-PTY
8h 12m1 stop
Delta Logo
3:37 pm - 11:00 pmPTY-SDF
7h 23m1 stop
$547Delta
Find Deal
mer., nov. 19 - dim., nov. 23

American Airlines flights from Louisville to Panama City

Our best American Airlines deals on Louisville to Panama City flight tickets
American Airlines
Mar 20
SDF6:31 amLouisville Intl
8h 49m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Apr 1
PTY1:50 pmPanama City Tocumen Intl
9h 24m
1 stop
SDF12:14 amLouisville Intl
$424
Find similar
American Airlines
Jan 15
SDF6:32 pmLouisville Intl
18h 55m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 18
PTY4:50 pmPanama City Tocumen Intl
17h 12m
2 stops
SDF10:02 amLouisville Intl
$440
Find similar
American Airlines
Jan 15
SDF3:33 pmLouisville Intl
21h 54m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 18
PTY4:50 pmPanama City Tocumen Intl
18h 25m
1 stop
SDF11:15 amLouisville Intl
$450
Find similar

Delta flights from Louisville to Panama City

Our best Delta deals on Louisville to Panama City flight tickets
Delta
May 2
SDF7:00 amLouisville Intl
6h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
May 5
PTY2:20 pmPanama City Tocumen Intl
8h 37m
1 stop
SDF11:57 pmLouisville Intl
$431
Find similar
Delta
Nov 19
SDF6:00 amLouisville Intl
8h 12m
1 stop
PTY2:12 pmPanama City Tocumen Intl
Nov 23
PTY3:37 pmPanama City Tocumen Intl
7h 23m
1 stop
SDF11:00 pmLouisville Intl
$547
Find similar
Delta
Nov 28
SDF6:00 amLouisville Intl
13h 59m
1 stop
PTY7:59 pmPanama City Tocumen Intl
Dec 1
PTY3:37 pmPanama City Tocumen Intl
7h 23m
1 stop
SDF11:00 pmLouisville Intl
$639
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated novembre 6, 2025.
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

ven. 3/20

6:31 am-2:20 pm

1 stop8h 49m

Panama City Tocumen Intl

mer. 4/1

1:50 pm-12:14 am

1 stop9h 24m

$424

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

jeu. 12/4

9:31 am-7:38 pm

1 stop10h 07m

Panama City Tocumen Intl

jeu. 12/11

4:41 pm-11:32 am

2 stops18h 51m

$428

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

sam. 5/2

7:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

mar. 5/5

2:20 pm-11:57 pm

1 stop8h 37m

$431

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

jeu. 12/4

7:10 am-7:38 pm

1 stop12h 28m

Panama City Tocumen Intl

jeu. 12/11

4:41 pm-7:54 pm

1 stop27h 13m

$432

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

mer. 12/3

7:10 am-7:38 pm

1 stop12h 28m

Panama City Tocumen Intl

dim. 12/7

8:55 am-9:57 pm

1 stop13h 02m

$433

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

sam. 5/2

7:30 am-6:37 pm

2 stops12h 07m

Panama City Tocumen Intl

mar. 5/5

7:55 am-10:09 pm

2 stops13h 14m

$435

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

mer. 12/3

7:00 am-7:38 pm

2 stops12h 38m

Panama City Tocumen Intl

dim. 12/7

8:55 am-10:29 pm

2 stops13h 34m

$437

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

ven. 3/6

6:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

ven. 3/13

11:35 am-9:30 pm

1 stop8h 55m

$438

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

jeu. 1/15

6:32 pm-1:27 pm

2 stops18h 55m

Panama City Tocumen Intl

dim. 1/18

4:50 pm-10:02 am

2 stops17h 12m

$440

LouisvillePanama City

SDF - PTY

SDFPTY

Louisville Intl

mer. 11/19

6:00 am-2:12 pm

1 stop8h 12m

Panama City Tocumen Intl

dim. 11/23

3:37 pm-11:00 pm

1 stop7h 23m

$547

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Louisville to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Louisville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $410. If you’re not able to fly to Panama City in September, then May is your next best option. Flight prices from Louisville to Panama City during May average around $423.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Monday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $395. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $551. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Louisville to Panama City during this time can be as low as $365. Try not to purchase tickets in the morning because they tend to be around $474. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Louisville to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Panama City (SDF to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City

Direct flights

None
There are no direct flights from Louisville to Panama City. There are no popular flight routes from Louisville to Panama City.
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  • How far is Louisville Intl to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 2057.4 mi away from Louisville Intl. 6h 55m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Louisville to Panama City?

Best airlines flying from Louisville to Panama City

Compare and see reviews for airlines that fly from Louisville to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $351Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
DeltaPriceFrom $392Free CancellationRating
7.9
8,001 reviews
Search Delta flights
American AirlinesPriceFrom $410Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

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Why should I use momondo to find a flight deal from Louisville to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Louisville to Panama City with flexible booking policies on momondo?

All flight searches from Louisville to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Louisville to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Panama City.

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