Cheap flights from Louisville to Panama City from $315
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Panama City departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Find the cheapest flights from Louisville to Panama City
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Delta flights from Louisville to Panama City
Our best Delta deals on Louisville to Panama City flight tickets
American Airlines flights from Louisville to Panama City
Our best American Airlines deals on Louisville to Panama City flight tickets
momondo Fare Finder
Use the filters below to find and compare flights from Louisville to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Fri 2/26
6:00 am-3:30 pm
1 stop9h 30m
Panama City Tocumen Intl
Wed 3/3
4:31 pm-12:56 am
1 stop8h 25m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Tue 4/6
6:01 am-12:36 pm
1 stop7h 35m
Panama City Tocumen Intl
Fri 4/16
1:49 pm-11:59 pm
1 stop9h 10m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Thu 12/10
7:05 am-2:45 pm
1 stop7h 40m
Panama City Tocumen Intl
Thu 1/14
8:55 am-9:59 pm
1 stop13h 04m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Thu 12/3
9:10 am-5:12 pm
1 stop8h 02m
Panama City Tocumen Intl
Mon 12/7
11:35 am-9:59 pm
1 stop10h 24m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Fri 2/26
6:00 am-3:30 pm
1 stop9h 30m
Panama City Tocumen Intl
Wed 3/3
4:31 pm-12:36 pm
2 stops20h 05m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Sun 1/10
5:43 pm-5:12 pm
2 stops23h 29m
Panama City Tocumen Intl
Wed 1/27
11:35 am-8:19 pm
1 stop8h 44m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Mon 11/9
6:00 am-2:02 pm
1 stop8h 02m
Panama City Tocumen Intl
Thu 11/19
3:29 pm-12:10 am
1 stop8h 41m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Tue 11/10
6:00 am-2:02 pm
1 stop8h 02m
Panama City Tocumen Intl
Thu 11/19
3:29 pm-10:53 pm
1 stop7h 24m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Sat 12/5
2:25 pm-2:10 am
2 stops11h 45m
Panama City Tocumen Intl
Fri 1/1
5:30 am-7:55 pm
2 stops14h 25m
LouisvillePanama City
SDF Louisville Intl - PTY Panama City Tocumen Intl
SDFPTY
Louisville Intl
Thu 12/10
9:10 am-5:12 pm
1 stop8h 02m
Panama City Tocumen Intl
Wed 1/6
11:35 am-1:36 pm
1 stop26h 01m
See travel insights to Panama City from
How to get the cheapest flight ticket from Louisville to Panama City
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Panama City?
In general, February is the cheapest month to fly from Louisville to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $430. If you’re not able to fly to Panama City in February, then April is your next best option. Flight prices from Louisville to Panama City during April average around $481.
Can stopping save me money on Louisville to Panama City flights?
You could potentially save up to 47% on your flight if you consider stops on a Louisville to Panama City flight.
What is the cheapest airline that flies from Louisville Intl to Panama City Tocumen Intl?
United Airlines, Delta, and American Airlines are the most popular carriers operating from Louisville Intl to Panama City Tocumen Intl
What airlines fly to Panama City?
United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama City from Louisville according to our data. United Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.
Which airport is the most popular layover for flights between Louisville and Panama City?
Houston (IAH) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.
Which layover airport offers the lowest fares from Louisville to Panama City?
Flights via Houston (IAH) offer the lowest average round-trip price of $452.
Which layover airport has the shortest travel time from Louisville to Panama City?
Flights connecting via Houston (IAH) have the shortest average one-way travel time: 7h 52m.
Which layover airport has the shortest connection time from Louisville to Panama City?
Atlanta (ATL) has the shortest average layover time for this route: 2h 45m.
When to book flights from Louisville to Panama City
Cheap Louisville to Panama City (SDF to PTY) flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Louisville to Panama City
Frequently asked questions about flying from Louisville to Panama City
How far is Louisville Intl to Panama City Tocumen Intl by plane?
Panama City Tocumen Intl is 2057.4 mi away from Louisville Intl. 6h 54m is a normal flight duration for this route.
When did momondo last update prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?
Prices for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport?
There are 3 operators available for flights from Louisville Intl Airport to Panama City Tocumen Intl Airport as of October 2026.
How old do you have to be to fly from Louisville Intl Airport to Panama City Tocumen Intl Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Louisville Intl Airport to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Louisville to Panama City?
Based on momondo bookings for flights between Louisville and Panama City, the leading airline is United Airlines, making up 52% of the total bookings. Other popular airlines include Delta with 29% and American Airlines with 19%.
Best airlines flying from Louisville to Panama City
Compare and see reviews for airlines that fly from Louisville to Panama City with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $430 | Free Cancellation | Rating 7.4 10,322 reviews | |||
| PriceFrom $514 | Free Cancellation | Rating 7.0 12,146 reviews | |||
| PriceFrom $558 | Free Cancellation | Rating 7.8 8,646 reviews |
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsWhy use momondo?
Why should I use momondo to find a flight deal from Louisville to Panama City?
momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Louisville to Panama City. momondo saves you time and could save you money on your trip.
Can I find flights from Louisville to Panama City with flexible booking policies on momondo?
All flight searches from Louisville to Panama City on momondo can be filtered to show those which offer flexible booking policies.
How can momondo help me find flights from Louisville to Panama City?
momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Louisville to Panama City.
I’m not ready to book a flight from Louisville to Panama City right now. Can momondo alert me if prices change?
Price alerts on flights to Panama City from Louisville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.