Cheap flights from Las Vegas to Panama City from $263

In general, October is the cheapest month to fly from Las Vegas to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $517. If you’re not able to fly to Panama City in October, then August is your next best option. Flight prices from Las Vegas to Panama City during August average around $560.

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $583. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $683. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Fly from Las Vegas Harry Reid Intl to Panama City Tocumen Intl for the best Las Vegas Harry Reid Intl - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Las Vegas when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $647 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Las Vegas for as low as $400 on momondo.

There are 3 cabin classes available to choose from on Las Vegas Harry Reid Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 55% on your flight if you consider stops on a Las Vegas to Panama City flight.

Avianca is the most popular carrier operating from Las Vegas Harry Reid Intl to Panama City Tocumen Intl

Copa Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Panama City from Las Vegas according to our data. Copa Airlines is the first choice among our users, with 71% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

Historically, on average around 7% of flights between Las Vegas and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 85 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 7% of their flights experiencing any sort of delay.

Houston (IAH) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Flights via Atlanta (ATL) offer the lowest average round-trip price of $495.

Flights connecting via Houston (IAH) have the shortest average one-way travel time: 8h 08m.

Houston (IAH) has the shortest average layover time for this route: 1h 29m.

As of April 2026, 1 flights take off from Las Vegas and land in Panama City each day. The most common flight departure time for this route is 12:00AM, with 100% of daily flights taking off in the morning.

8 flights are operational weekly from Las Vegas to Panama City as of April 2026. The most popular departure day for this route is Mon, with 25% of flights per week taking off on this day.