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Cheap flights from Indianapolis to Panama City from $221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Panama City departing on 5/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Indianapolis to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:45 am - 1:00 am
IND
-
PTY
19h 15m
2 stops
Multiple Airlines Logo
2:55 am - 10:48 pm
PTY
-
IND
19h 53m
2 stops
$445Multiple Airlines
Tue, Feb 24 - Mon, Mar 2
Multiple Airlines Logo
5:45 am - 12:40 am
IND
-
PTY
18h 55m
2 stops
Multiple Airlines Logo
2:55 am - 10:48 pm
PTY
-
IND
19h 53m
2 stops
$476Multiple Airlines
Wed, Feb 25 - Tue, Mar 3
Multiple Airlines Logo
5:45 am - 12:40 am
IND
-
PTY
18h 55m
2 stops
Multiple Airlines Logo
2:55 am - 10:48 pm
PTY
-
IND
18h 53m
2 stops
$485Multiple Airlines
Wed, Mar 4 - Sun, Mar 8
Multiple Airlines Logo
6:15 am - 9:10 pm
IND
-
PTY
15h 55m
2 stops
Multiple Airlines Logo
3:25 am - 10:38 pm
PTY
-
IND
18h 13m
2 stops
$506Multiple Airlines
Sun, May 3 - Fri, May 8
United Airlines Logo
11:37 am - 6:38 pm
IND
-
PTY
8h 01m
1 stop
United Airlines Logo
3:30 pm - 10:46 am
PTY
-
IND
18h 16m
1 stop
$511United Airlines
Tue, Mar 24 - Wed, Apr 1
United Airlines Logo
6:12 pm - 1:45 pm
IND
-
PTY
20h 33m
2 stops
United Airlines Logo
7:55 am - 9:32 pm
PTY
-
IND
12h 37m
1 stop
$515United Airlines
Tue, Mar 24 - Wed, Apr 1
American Airlines Logo
5:30 pm - 2:20 pm
IND
-
PTY
21h 50m
2 stops
American Airlines Logo
3:51 pm - 10:05 am
PTY
-
IND
17h 14m
1 stop
$535American Airlines
Sat, Mar 21 - Thu, Apr 2
American Airlines Logo
6:00 am - 12:36 pm
IND
-
PTY
7h 36m
1 stop
American Airlines Logo
1:49 pm - 11:57 pm
PTY
-
IND
9h 08m
1 stop
$536American Airlines
Fri, May 1 - Sun, May 10
American Airlines Logo
8:30 pm - 12:10 pm
IND
-
PTY
16h 40m
2 stops
American Airlines Logo
1:10 pm - 9:26 am
PTY
-
IND
19h 16m
2 stops
$540American Airlines
Wed, Jul 22 - Sun, Jul 26
United Airlines Logo
5:10 pm - 4:12 pm
IND
-
PTY
24h 02m
1 stop
United Airlines Logo
3:30 pm - 10:46 am
PTY
-
IND
18h 16m
1 stop
$541United Airlines
Sun, Apr 5 - Fri, Apr 10

Copa Airlines flights from Indianapolis to Panama City

Our best Copa Airlines deals on Indianapolis to Panama City flight tickets
Copa Airlines
Feb 7
IND6:45 amIndianapolis
8h 00m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Apr 7
PTY3:30 pmPanama City Tocumen Intl
18h 16m
1 stop
IND10:46 amIndianapolis
$589
Copa Airlines
Feb 7
IND6:45 amIndianapolis
8h 00m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Apr 7
PTY3:30 pmPanama City Tocumen Intl
18h 47m
2 stops
IND11:17 amIndianapolis
$594
Copa Airlines
Mar 22
IND6:00 amIndianapolis
14h 02m
1 stop
PTY7:02 pmPanama City Tocumen Intl
Mar 28
PTY3:41 pmPanama City Tocumen Intl
28h 51m
1 stop
IND9:32 pmIndianapolis
$630

American Airlines flights from Indianapolis to Panama City

Our best American Airlines deals on Indianapolis to Panama City flight tickets
American Airlines
Mar 21
IND5:30 pmIndianapolis
21h 50m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Apr 2
PTY3:51 pmPanama City Tocumen Intl
17h 14m
1 stop
IND10:05 amIndianapolis
$535
American Airlines
May 1
IND6:00 amIndianapolis
7h 36m
1 stop
PTY12:36 pmPanama City Tocumen Intl
May 10
PTY1:49 pmPanama City Tocumen Intl
9h 08m
1 stop
IND11:57 pmIndianapolis
$536
American Airlines
Jul 22
IND8:30 pmIndianapolis
16h 40m
2 stops
PTY12:10 pmPanama City Tocumen Intl
Jul 26
PTY1:10 pmPanama City Tocumen Intl
19h 16m
2 stops
IND9:26 amIndianapolis
$540

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Indianapolis to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 2/24

5:45 am-1:00 am

2 stops19h 15m

Panama City Tocumen Intl

Mon 3/2

2:55 am-10:48 pm

2 stops19h 53m

$445

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 2/25

5:45 am-12:40 am

2 stops18h 55m

Panama City Tocumen Intl

Tue 3/3

2:55 am-10:48 pm

2 stops19h 53m

$476

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 3/4

5:45 am-12:40 am

2 stops18h 55m

Panama City Tocumen Intl

Sun 3/8

2:55 am-10:48 pm

2 stops18h 53m

$485

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 5/3

6:15 am-9:10 pm

2 stops15h 55m

Panama City Tocumen Intl

Fri 5/8

3:25 am-10:38 pm

2 stops18h 13m

$506

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/24

11:37 am-6:38 pm

1 stop8h 01m

Panama City Tocumen Intl

Wed 4/1

3:30 pm-10:46 am

1 stop18h 16m

$511

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/24

6:12 pm-1:45 pm

2 stops20h 33m

Panama City Tocumen Intl

Wed 4/1

7:55 am-9:32 pm

1 stop12h 37m

$515

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

5:30 pm-2:20 pm

2 stops21h 50m

Panama City Tocumen Intl

Thu 4/2

3:51 pm-10:05 am

1 stop17h 14m

$535

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 5/1

6:00 am-12:36 pm

1 stop7h 36m

Panama City Tocumen Intl

Sun 5/10

1:49 pm-11:57 pm

1 stop9h 08m

$536

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 7/22

8:30 pm-12:10 pm

2 stops16h 40m

Panama City Tocumen Intl

Sun 7/26

1:10 pm-9:26 am

2 stops19h 16m

$540

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 4/5

5:10 pm-4:12 pm

1 stop24h 02m

Panama City Tocumen Intl

Fri 4/10

3:30 pm-10:46 am

1 stop18h 16m

$541

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Indianapolis to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Indianapolis and Panama City?

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Indianapolis to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $489. If you’re not able to fly to Panama City in September, then July is your next best option. Flight prices from Indianapolis to Panama City during July average around $509.

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $644 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Indianapolis for as low as $493 on momondo.

When to book flights from Indianapolis to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to Panama City (IND to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Panama City

Fastest flight time

7h 54m

Direct flights

None
The fastest flight from Indianapolis to Panama City takes 7h 54m
There are no direct flights from Indianapolis to Panama City. There are no popular flight routes from Indianapolis to Panama City.
Search flight deals

  • How far is Indianapolis to Panama City Tocumen Intl by plane?

    There are 2164.5 mi between Indianapolis and Panama City Tocumen Intl. 7h 54m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Indianapolis Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Indianapolis Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Indianapolis Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Indianapolis Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Indianapolis to Panama City?

Best airlines flying from Indianapolis to Panama City

Compare and see reviews for airlines that fly from Indianapolis to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
11,205 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights
DeltaPriceFrom $473Free CancellationRating
7.9
8,128 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Indianapolis to Panama City for you.

Can I find flights from Indianapolis to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Indianapolis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Indianapolis to Panama City?

Once you have performed a search for Indianapolis to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Indianapolis to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Indianapolis and alert you when they change.

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