Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Indianapolis to Panama City from $490

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Panama City departing on 1/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Indianapolis to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 1:27 pm
IND
-
PTY
7h 27m1 stop
American Airlines Logo
2:27 pm - 11:59 pm
PTY
-
IND
9h 32m1 stop
$490American Airlines
Tue, Jan 27 - Wed, Feb 4
American Airlines Logo
9:31 pm - 1:27 pm
IND
-
PTY
15h 56m2 stops
American Airlines Logo
2:27 pm - 11:59 pm
PTY
-
IND
9h 32m1 stop
$494American Airlines
Tue, Jan 27 - Wed, Feb 4
United Airlines Logo
9:00 am - 5:07 pm
IND
-
PTY
8h 07m1 stop
United Airlines Logo
10:00 am - 8:27 pm
PTY
-
IND
10h 27m1 stop
$510United Airlines
Mon, Jan 26 - Fri, Jan 30
United Airlines Logo
11:40 am - 7:38 pm
IND
-
PTY
7h 58m1 stop
United Airlines Logo
4:41 pm - 11:32 am
PTY
-
IND
18h 51m2 stops
$514United Airlines
Mon, Jan 26 - Fri, Jan 30
American Airlines Logo
6:00 am - 1:50 pm
IND
-
PTY
7h 50m1 stop
American Airlines Logo
4:05 pm - 10:12 am
PTY
-
IND
18h 07m1 stop
$515American Airlines
Tue, Feb 24 - Sun, Mar 1
United Airlines Logo
6:00 am - 6:38 pm
IND
-
PTY
13h 38m2 stops
United Airlines Logo
3:41 pm - 1:06 pm
PTY
-
IND
20h 25m2 stops
$519United Airlines
Thu, Mar 12 - Mon, Mar 16
United Airlines Logo
5:05 pm - 2:45 pm
IND
-
PTY
21h 40m1 stop
United Airlines Logo
4:41 pm - 10:48 am
PTY
-
IND
18h 07m1 stop
$520United Airlines
Mon, Jan 19 - Mon, Jan 26
American Airlines Logo
9:28 pm - 1:50 pm
IND
-
PTY
16h 22m2 stops
American Airlines Logo
4:05 pm - 1:05 pm
PTY
-
IND
21h 00m2 stops
$524American Airlines
Tue, Feb 24 - Sun, Mar 1
American Airlines Logo
7:23 pm - 2:22 pm
IND
-
PTY
19h 59m1 stop
American Airlines Logo
1:44 pm - 1:10 pm
PTY
-
IND
22h 26m2 stops
$526American Airlines
Sat, Mar 21 - Thu, Apr 2
United Airlines Logo
5:08 pm - 2:45 pm
IND
-
PTY
21h 37m1 stop
United Airlines Logo
4:41 pm - 11:30 pm
PTY
-
IND
30h 49m1 stop
$529United Airlines
Sun, Feb 22 - Sun, Mar 1

United Airlines flights from Indianapolis to Panama City

Our best United Airlines deals on Indianapolis to Panama City flight tickets
United Airlines
Jan 26
IND9:00 amIndianapolis
8h 07m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Jan 30
PTY10:00 amPanama City Tocumen Intl
10h 27m
1 stop
IND8:27 pmIndianapolis
$510
Find similar
United Airlines
Jan 26
IND11:40 amIndianapolis
7h 58m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 30
PTY4:41 pmPanama City Tocumen Intl
18h 51m
2 stops
IND11:32 amIndianapolis
$514
Find similar
United Airlines
Mar 12
IND6:00 amIndianapolis
13h 38m
2 stops
PTY6:38 pmPanama City Tocumen Intl
Mar 16
PTY3:41 pmPanama City Tocumen Intl
20h 25m
2 stops
IND1:06 pmIndianapolis
$519
Find similar

American Airlines flights from Indianapolis to Panama City

Our best American Airlines deals on Indianapolis to Panama City flight tickets
American Airlines
Jan 27
IND6:00 amIndianapolis
7h 27m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 4
PTY2:27 pmPanama City Tocumen Intl
9h 32m
1 stop
IND11:59 pmIndianapolis
$490
Find similar
American Airlines
Jan 27
IND9:31 pmIndianapolis
15h 56m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 4
PTY2:27 pmPanama City Tocumen Intl
9h 32m
1 stop
IND11:59 pmIndianapolis
$494
Find similar
American Airlines
Feb 24
IND6:00 amIndianapolis
7h 50m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Mar 1
PTY4:05 pmPanama City Tocumen Intl
18h 07m
1 stop
IND10:12 amIndianapolis
$515
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 5, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 1/27

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Wed 2/4

2:27 pm-11:59 pm

1 stop9h 32m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 1/27

9:31 pm-1:27 pm

2 stops15h 56m

Panama City Tocumen Intl

Wed 2/4

2:27 pm-11:59 pm

1 stop9h 32m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 1/26

9:00 am-5:07 pm

1 stop8h 07m

Panama City Tocumen Intl

Fri 1/30

10:00 am-8:27 pm

1 stop10h 27m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 1/26

11:40 am-7:38 pm

1 stop7h 58m

Panama City Tocumen Intl

Fri 1/30

4:41 pm-11:32 am

2 stops18h 51m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 2/24

6:00 am-1:50 pm

1 stop7h 50m

Panama City Tocumen Intl

Sun 3/1

4:05 pm-10:12 am

1 stop18h 07m

$515

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 3/12

6:00 am-6:38 pm

2 stops13h 38m

Panama City Tocumen Intl

Mon 3/16

3:41 pm-1:06 pm

2 stops20h 25m

$519

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 1/19

5:05 pm-2:45 pm

1 stop21h 40m

Panama City Tocumen Intl

Mon 1/26

4:41 pm-10:48 am

1 stop18h 07m

$520

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 2/24

9:28 pm-1:50 pm

2 stops16h 22m

Panama City Tocumen Intl

Sun 3/1

4:05 pm-1:05 pm

2 stops21h 00m

$524

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

7:23 pm-2:22 pm

1 stop19h 59m

Panama City Tocumen Intl

Thu 4/2

1:44 pm-1:10 pm

2 stops22h 26m

$526

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 2/22

5:08 pm-2:45 pm

1 stop21h 37m

Panama City Tocumen Intl

Sun 3/1

4:41 pm-11:30 pm

1 stop30h 49m

$529

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Indianapolis to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Indianapolis to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $489. If you’re not able to fly to Panama City in September, then July is your next best option. Flight prices from Indianapolis to Panama City during July average around $509.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $491. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $623. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Indianapolis to Panama City during this time can be as low as $543. Try not to purchase tickets in the morning because they tend to be around $589. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $626 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Indianapolis for as low as $479 on momondo.

When to book flights from Indianapolis to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Indianapolis to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Indianapolis to Panama City (IND to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Panama City

Fastest flight time

7h 45m

Direct flights

None
The fastest flight from Indianapolis to Panama City takes 7h 45m
There are no direct flights from Indianapolis to Panama City. There are no popular flight routes from Indianapolis to Panama City.
Search flight deals

  • How far is Indianapolis to Panama City Tocumen Intl by plane?

    There are 2164.5 mi between Indianapolis and Panama City Tocumen Intl. 7h 27m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Indianapolis Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Indianapolis Airport to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Indianapolis Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Indianapolis Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indianapolis Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Indianapolis to Panama City?

Best airlines flying from Indianapolis to Panama City

Compare and see reviews for airlines that fly from Indianapolis to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $469Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights
DeltaPriceFrom $489Free CancellationRating
7.9
8,010 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Indianapolis to Panama City for you.

Can I find flights from Indianapolis to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Indianapolis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Indianapolis to Panama City?

Once you have performed a search for Indianapolis to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Indianapolis to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Indianapolis and alert you when they change.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 1/4
Sun 1/11
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama