Cheap flights from Houston to Panama City from $184

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Panama City departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:30 am - 6:55 pm
IAH
-
PTY
10h 25m1 stop
Multiple Airlines Logo
2:55 am - 1:10 pm
PTY
-
IAH
35h 15m2 stops
$432Multiple Airlines
Wed, Jan 28 - Tue, Feb 3
Multiple Airlines Logo
6:30 am - 5:10 pm
IAH
-
PTY
9h 40m1 stop
Multiple Airlines Logo
5:50 pm - 8:23 pm
PTY
-
IAH
27h 33m2 stops
$447Multiple Airlines
Mon, Jan 19 - Mon, Feb 2
Multiple Airlines Logo
4:35 pm - 8:11 am
IAH
-
PTY
14h 36m1 stop
Multiple Airlines Logo
5:50 pm - 8:40 am
PTY
-
IAH
39h 50m2 stops
$454Multiple Airlines
Thu, Jan 29 - Thu, Feb 5
Multiple Airlines Logo
4:35 pm - 10:30 am
IAH
-
PTY
16h 55m1 stop
Multiple Airlines Logo
2:55 am - 1:10 pm
PTY
-
IAH
35h 15m2 stops
$456Multiple Airlines
Wed, Jan 14 - Tue, Jan 20
Delta Logo
5:45 am - 1:55 pm
HOU
-
PTY
7h 10m1 stop
Delta Logo
3:20 pm - 10:33 pm
PTY
-
HOU
8h 13m1 stop
$754Delta
Thu, Jan 29 - Thu, Feb 5
American Airlines Logo
6:36 pm - 3:38 pm
HOU
-
PTY
20h 02m2 stops
American Airlines Logo
4:05 pm - 9:43 am
PTY
-
HOU
18h 38m2 stops
$758American Airlines
Thu, Jan 29 - Thu, Feb 12
American Airlines Logo
4:20 pm - 12:40 pm
HOU
-
PTY
20h 20m2 stops
American Airlines Logo
3:10 pm - 9:43 am
PTY
-
HOU
18h 33m2 stops
$759American Airlines
Tue, Mar 10 - Wed, Mar 18
American Airlines Logo
6:36 pm - 3:52 pm
HOU
-
PTY
20h 16m2 stops
American Airlines Logo
4:50 pm - 12:19 pm
PTY
-
HOU
20h 29m2 stops
$778American Airlines
Fri, Jan 30 - Fri, Feb 6
Delta Logo
5:45 am - 1:55 pm
HOU
-
PTY
7h 10m1 stop
Delta Logo
3:20 pm - 10:33 pm
PTY
-
HOU
8h 13m1 stop
$804Delta
Sat, Jan 31 - Sun, Feb 8
Delta Logo
5:45 am - 1:55 pm
HOU
-
PTY
7h 10m1 stop
Delta Logo
3:20 pm - 10:33 pm
PTY
-
HOU
8h 13m1 stop
$805Delta
Sat, Jan 31 - Sun, Feb 8

Delta flights from Houston to Panama City

Our best Delta deals on Houston to Panama City flight tickets
Delta
Jan 29
HOU5:45 amHouston Hobby
7h 10m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Feb 5
PTY3:20 pmPanama City Tocumen Intl
8h 13m
1 stop
HOU10:33 pmHouston Hobby
Delta
Jan 31
HOU5:45 amHouston Hobby
7h 10m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Feb 8
PTY3:20 pmPanama City Tocumen Intl
8h 13m
1 stop
HOU10:33 pmHouston Hobby
Delta
Jan 31
HOU5:45 amHouston Hobby
7h 10m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Feb 8
PTY3:20 pmPanama City Tocumen Intl
8h 13m
1 stop
HOU10:33 pmHouston Hobby

American Airlines flights from Houston to Panama City

Our best American Airlines deals on Houston to Panama City flight tickets
American Airlines
Jan 29
HOU6:36 pmHouston Hobby
20h 02m
2 stops
PTY3:38 pmPanama City Tocumen Intl
Feb 12
PTY4:05 pmPanama City Tocumen Intl
18h 38m
2 stops
HOU9:43 amHouston Hobby
American Airlines
Mar 10
HOU4:20 pmHouston Hobby
20h 20m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Mar 18
PTY3:10 pmPanama City Tocumen Intl
18h 33m
2 stops
HOU9:43 amHouston Hobby
American Airlines
Jan 30
HOU6:36 pmHouston Hobby
20h 16m
2 stops
PTY3:52 pmPanama City Tocumen Intl
Feb 6
PTY4:50 pmPanama City Tocumen Intl
20h 29m
2 stops
HOU12:19 pmHouston Hobby

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 1, 2026.
Use the filters below to find and compare flights from Houston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 1/28

7:30 am-6:55 pm

1 stop10h 25m

Panama City Tocumen Intl

Tue 2/3

2:55 am-1:10 pm

2 stops35h 15m

$432

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 1/19

6:30 am-5:10 pm

1 stop9h 40m

Panama City Tocumen Intl

Mon 2/2

5:50 pm-8:23 pm

2 stops27h 33m

$447

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 1/29

4:35 pm-8:11 am

1 stop14h 36m

Panama City Tocumen Intl

Thu 2/5

5:50 pm-8:40 am

2 stops39h 50m

$454

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 1/14

4:35 pm-10:30 am

1 stop16h 55m

Panama City Tocumen Intl

Tue 1/20

2:55 am-1:10 pm

2 stops35h 15m

$456

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Thu 1/29

5:45 am-1:55 pm

1 stop7h 10m

Panama City Tocumen Intl

Thu 2/5

3:20 pm-10:33 pm

1 stop8h 13m

$754

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Thu 1/29

6:36 pm-3:38 pm

2 stops20h 02m

Panama City Tocumen Intl

Thu 2/12

4:05 pm-9:43 am

2 stops18h 38m

$758

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 3/10

4:20 pm-12:40 pm

2 stops20h 20m

Panama City Tocumen Intl

Wed 3/18

3:10 pm-9:43 am

2 stops18h 33m

$759

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Fri 1/30

6:36 pm-3:52 pm

2 stops20h 16m

Panama City Tocumen Intl

Fri 2/6

4:50 pm-12:19 pm

2 stops20h 29m

$778

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Sat 1/31

5:45 am-1:55 pm

1 stop7h 10m

Panama City Tocumen Intl

Sun 2/8

3:20 pm-10:33 pm

1 stop8h 13m

$804

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Sat 1/31

5:45 am-1:55 pm

1 stop7h 10m

Panama City Tocumen Intl

Sun 2/8

3:20 pm-10:33 pm

1 stop8h 13m

$805

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Houston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Panama City?

What is the cheapest month to fly to Panama City?

In general, January is the cheapest month to fly from Houston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $787. If you’re not able to fly to Panama City in January, then May is your next best option. Flight prices from Houston to Panama City during May average around $858.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Houston to Panama City during this time can be as low as $889. Try not to purchase tickets in the morning because they tend to be around $904. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Houston to Panama City Tocumen Intl flight route?

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Houston when booking week ahead of your departure date. In general, you can expect to find flights to Panama City for around $904 when searching week out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Houston for as low as $733 on momondo.

What cabin class options are available on Houston to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Houston to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Panama City

Fastest flight time

4h 11m

Direct flights

Every day

Airports in Panama City

1 airport
The fastest flight from Houston to Panama City takes 4h 11m
Direct flights go from Houston to Panama City every day.
There is 1 airport in Panama City. From Houston there are direct flights to Panama City Tocumen Intl (PTY).
  • How far is Houston to Panama City Tocumen Intl by plane?

    Houston and Panama City Tocumen Intl are 1762.1 mi apart from one another. A reasonable flight in good conditions will take 4h 11m.

  • When did momondo last update prices for flights from Houston to Panama City Tocumen Intl Airport?

    Prices for flights from Houston to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Houston to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Houston to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Panama City

Compare and see reviews for airlines that fly from Houston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $738Free CancellationRating
7.4
9,131 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $846Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Houston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Houston to Panama City with flexible booking policies on momondo?

Flights from Houston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Houston.

I’m not ready to book a flight from Houston to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Houston are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Sat 1/31
Sat 2/7

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