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Cheap flights from Houston to Panama City from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Panama City departing on 10/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Houston to Panama City

Cheap round-trip flights

Logo
12:47 pm - 8:19 pmIAH-PTY
7h 32m1 stop
Logo
12:03 pm - 10:42 pmPTY-IAH
10h 39m1 stop
$412
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Mon, Sep 29 - Thu, Oct 2
Logo
10:55 am - 7:20 pmIAH-PTY
8h 25m1 stop
Logo
9:33 pm - 10:00 amPTY-IAH
13h 27m1 stop
$415
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Fri, Oct 31 - Sun, Nov 2
Logo
10:55 am - 7:29 pmIAH-PTY
8h 34m1 stop
Logo
9:33 pm - 10:00 amPTY-IAH
12h 27m1 stop
$419
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Mon, Oct 20 - Thu, Oct 23
Logo
5:45 am - 12:35 pmIAH-PTY
30h 50m3 stops
Logo
10:05 pm - 9:17 pmPTY-IAH
23h 12m3 stops
$429
Find Deal
Thu, Oct 16 - Mon, Oct 20
Delta Logo
6:00 am - 12:56 pmHOU-PTY
6h 56m1 stop
Delta Logo
3:21 pm - 11:00 pmPTY-HOU
8h 39m1 stop
$743Delta
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Tue, Oct 28 - Tue, Nov 4
American Airlines Logo
6:39 pm - 2:03 pmHOU-PTY
19h 24m2 stops
American Airlines Logo
3:15 pm - 8:28 amPTY-HOU
17h 13m2 stops
$758American Airlines
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Tue, Oct 14 - Fri, Oct 24
Delta Logo
6:00 am - 12:56 pmHOU-PTY
6h 56m1 stop
Delta Logo
2:21 pm - 11:00 pmPTY-HOU
8h 39m1 stop
$768Delta
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Tue, Oct 14 - Fri, Oct 24
American Airlines Logo
6:07 pm - 1:53 pmHOU-PTY
18h 46m2 stops
American Airlines Logo
2:45 pm - 8:38 amPTY-HOU
18h 53m2 stops
$778American Airlines
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Sat, Jan 3 - Tue, Feb 3
American Airlines Logo
8:19 pm - 1:48 pmHOU-PTY
16h 29m2 stops
American Airlines Logo
4:37 pm - 9:38 amPTY-HOU
18h 01m2 stops
$783American Airlines
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Thu, Dec 4 - Sun, Dec 14
Delta Logo
6:00 am - 12:56 pmHOU-PTY
6h 56m1 stop
Delta Logo
2:21 pm - 11:00 pmPTY-HOU
8h 39m1 stop
$893Delta
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Thu, Oct 16 - Mon, Oct 20

American Airlines flights from Houston to Panama City

Our best American Airlines deals on Houston to Panama City flight tickets
American Airlines
Oct 14
HOU6:39 pmHouston Hobby
19h 24m
2 stops
PTY2:03 pmPanama City Tocumen Intl
Oct 24
PTY3:15 pmPanama City Tocumen Intl
17h 13m
2 stops
HOU8:28 amHouston Hobby
$758
Find similar
American Airlines
Jan 3
HOU6:07 pmHouston Hobby
18h 46m
2 stops
PTY1:53 pmPanama City Tocumen Intl
Feb 3
PTY2:45 pmPanama City Tocumen Intl
18h 53m
2 stops
HOU8:38 amHouston Hobby
$778
Find similar
American Airlines
Dec 4
HOU8:19 pmHouston Hobby
16h 29m
2 stops
PTY1:48 pmPanama City Tocumen Intl
Dec 14
PTY4:37 pmPanama City Tocumen Intl
18h 01m
2 stops
HOU9:38 amHouston Hobby
$783
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Delta flights from Houston to Panama City

Our best Delta deals on Houston to Panama City flight tickets
Delta
Oct 28
HOU6:00 amHouston Hobby
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Nov 4
PTY3:21 pmPanama City Tocumen Intl
8h 39m
1 stop
HOU11:00 pmHouston Hobby
$743
Find similar
Delta
Oct 14
HOU6:00 amHouston Hobby
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 24
PTY2:21 pmPanama City Tocumen Intl
8h 39m
1 stop
HOU11:00 pmHouston Hobby
$768
Find similar
Delta
Oct 16
HOU6:00 amHouston Hobby
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 20
PTY2:21 pmPanama City Tocumen Intl
8h 39m
1 stop
HOU11:00 pmHouston Hobby
$893
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Houston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 9/29

12:47 pm-8:19 pm

1 stop7h 32m

Panama City Tocumen Intl

Thu 10/2

12:03 pm-10:42 pm

1 stop10h 39m

$412

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Fri 10/31

10:55 am-7:20 pm

1 stop8h 25m

Panama City Tocumen Intl

Sun 11/2

9:33 pm-10:00 am

1 stop13h 27m

$415

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 10/20

10:55 am-7:29 pm

1 stop8h 34m

Panama City Tocumen Intl

Thu 10/23

9:33 pm-10:00 am

1 stop12h 27m

$419

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 10/16

5:45 am-12:35 pm

3 stops30h 50m

Panama City Tocumen Intl

Mon 10/20

10:05 pm-9:17 pm

3 stops23h 12m

$429

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 10/28

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Tue 11/4

3:21 pm-11:00 pm

1 stop8h 39m

$743

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 10/14

6:39 pm-2:03 pm

2 stops19h 24m

Panama City Tocumen Intl

Fri 10/24

3:15 pm-8:28 am

2 stops17h 13m

$758

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 10/14

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Fri 10/24

2:21 pm-11:00 pm

1 stop8h 39m

$768

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Sat 1/3

6:07 pm-1:53 pm

2 stops18h 46m

Panama City Tocumen Intl

Tue 2/3

2:45 pm-8:38 am

2 stops18h 53m

$778

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Thu 12/4

8:19 pm-1:48 pm

2 stops16h 29m

Panama City Tocumen Intl

Sun 12/14

4:37 pm-9:38 am

2 stops18h 01m

$783

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Thu 10/16

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Mon 10/20

2:21 pm-11:00 pm

1 stop8h 39m

$893

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Houston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Panama City?

What is the cheapest month to fly to Panama City?

In general, January is the cheapest month to fly from Houston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $788. If you’re not able to fly to Panama City in January, then June is your next best option. Flight prices from Houston to Panama City during June average around $845.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Saturday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $802. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $1,137. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Houston to Panama City during this time can be as low as $467. Try not to purchase tickets in the morning because they tend to be around $1,018. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Houston to Panama City Tocumen Intl flight route?

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $897 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Houston for as low as $435 on momondo.

What cabin class options are available on Houston to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Houston to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Panama City

Fastest flight time

4h 11m

Direct flights

Every day

Airports in Panama City

1 airport
The fastest flight from Houston to Panama City takes 4h 11m
Direct flights go from Houston to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
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  • How far is Houston to Panama City Tocumen Intl by plane?

    Houston and Panama City Tocumen Intl are 1762.1 mi apart from one another. A reasonable flight in good conditions will take 6h 54m.

  • When did momondo last update prices for flights from Houston to Panama City Tocumen Intl Airport?

    Prices for flights from Houston to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Houston to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Houston to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Panama City

Compare and see reviews for airlines that fly from Houston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $318Free CancellationRating
6.7
2,435 reviews
Search Avianca flights
United AirlinesPriceFrom $738Free CancellationRating
7.4
8,929 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $824Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Houston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Houston to Panama City with flexible booking policies on momondo?

Flights from Houston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Houston.

I’m not ready to book a flight from Houston to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Houston are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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