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Cheap flights from Houston to Panama City from $146

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Panama City departing on 2/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:08 pm - 8:50 am
IAH
-
PTY
17h 42m
2 stops
Multiple Airlines Logo
3:50 pm - 1:49 pm
PTY
-
IAH
21h 59m
1 stop
$429Multiple Airlines
mar., mar. 24 - mar., abr. 7
Multiple Airlines Logo
3:08 pm - 8:50 am
IAH
-
PTY
17h 42m
2 stops
Multiple Airlines Logo
3:50 pm - 1:49 pm
PTY
-
IAH
21h 59m
1 stop
$435Multiple Airlines
mié., mar. 25 - mar., abr. 7
Multiple Airlines Logo
3:29 pm - 1:55 am
IAH
-
PTY
10h 26m
1 stop
Multiple Airlines Logo
3:20 am - 11:17 am
PTY
-
IAH
31h 57m
2 stops
$446Multiple Airlines
lun., abr. 6 - jue., abr. 9
Multiple Airlines Logo
5:24 pm - 4:30 pm
IAH
-
PTY
23h 06m
2 stops
Multiple Airlines Logo
5:30 am - 1:49 pm
PTY
-
IAH
8h 19m
1 stop
$449Multiple Airlines
mié., abr. 8 - lun., abr. 13
Multiple Airlines Logo
2:20 pm - 4:30 pm
IAH
-
PTY
26h 10m
2 stops
Multiple Airlines Logo
3:50 pm - 1:49 pm
PTY
-
IAH
21h 59m
1 stop
$450Multiple Airlines
jue., abr. 9 - dom., abr. 12
Delta Logo
5:23 pm - 1:02 pm
HOU
-
PTY
19h 39m
1 stop
Delta Logo
2:27 pm - 9:20 am
PTY
-
HOU
18h 53m
1 stop
$774Delta
dom., abr. 26 - mié., may. 6
Delta Logo
5:25 am - 1:50 pm
HOU
-
PTY
7h 25m
1 stop
Delta Logo
3:15 pm - 10:28 pm
PTY
-
HOU
8h 13m
1 stop
$775Delta
lun., feb. 23 - jue., mar. 5
American Airlines Logo
4:20 pm - 12:40 pm
HOU
-
PTY
20h 20m
2 stops
American Airlines Logo
3:10 pm - 9:43 am
PTY
-
HOU
18h 33m
2 stops
$779American Airlines
mar., mar. 10 - mié., mar. 18
Delta Logo
6:00 am - 1:02 pm
HOU
-
PTY
7h 02m
1 stop
Delta Logo
2:20 pm - 9:20 am
PTY
-
HOU
19h 00m
1 stop
$787Delta
mar., abr. 28 - jue., may. 7
American Airlines Logo
4:21 pm - 1:40 pm
HOU
-
PTY
20h 19m
2 stops
American Airlines Logo
3:10 pm - 9:43 am
PTY
-
HOU
18h 33m
2 stops
$799American Airlines
lun., mar. 2 - lun., mar. 9

LATAM Airlines flights from Houston to Panama City

Our best LATAM Airlines deals on Houston to Panama City flight tickets
LATAM Airlines
Apr 30
HOU6:00 amHouston Hobby
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 5
PTY2:27 pmPanama City Tocumen Intl
8h 38m
1 stop
HOU11:05 pmHouston Hobby
$1,077
LATAM Airlines
May 1
HOU6:00 amHouston Hobby
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 5
PTY2:27 pmPanama City Tocumen Intl
8h 38m
1 stop
HOU11:05 pmHouston Hobby
$1,102
LATAM Airlines
Feb 25
HOU5:25 amHouston Hobby
7h 25m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Mar 1
PTY3:15 pmPanama City Tocumen Intl
26h 13m
1 stop
HOU4:28 pmHouston Hobby
$1,116

Delta flights from Houston to Panama City

Our best Delta deals on Houston to Panama City flight tickets
Delta
Apr 26
HOU5:23 pmHouston Hobby
19h 39m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 6
PTY2:27 pmPanama City Tocumen Intl
18h 53m
1 stop
HOU9:20 amHouston Hobby
$774
Delta
Feb 23
HOU5:25 amHouston Hobby
7h 25m
1 stop
PTY1:50 pmPanama City Tocumen Intl
Mar 5
PTY3:15 pmPanama City Tocumen Intl
8h 13m
1 stop
HOU10:28 pmHouston Hobby
$775
Delta
Apr 28
HOU6:00 amHouston Hobby
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 7
PTY2:20 pmPanama City Tocumen Intl
19h 00m
1 stop
HOU9:20 amHouston Hobby
$787

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated enero 26, 2026.
Use the filters below to find and compare flights from Houston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

mar. 3/24

3:08 pm-8:50 am

2 stops17h 42m

Panama City Tocumen Intl

mar. 4/7

3:50 pm-1:49 pm

1 stop21h 59m

$429

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

mié. 3/25

3:08 pm-8:50 am

2 stops17h 42m

Panama City Tocumen Intl

mar. 4/7

3:50 pm-1:49 pm

1 stop21h 59m

$435

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

lun. 4/6

3:29 pm-1:55 am

1 stop10h 26m

Panama City Tocumen Intl

jue. 4/9

3:20 am-11:17 am

2 stops31h 57m

$446

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

mié. 4/8

5:24 pm-4:30 pm

2 stops23h 06m

Panama City Tocumen Intl

lun. 4/13

5:30 am-1:49 pm

1 stop8h 19m

$449

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

jue. 4/9

2:20 pm-4:30 pm

2 stops26h 10m

Panama City Tocumen Intl

dom. 4/12

3:50 pm-1:49 pm

1 stop21h 59m

$450

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

dom. 4/26

5:23 pm-1:02 pm

1 stop19h 39m

Panama City Tocumen Intl

mié. 5/6

2:27 pm-9:20 am

1 stop18h 53m

$774

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

lun. 2/23

5:25 am-1:50 pm

1 stop7h 25m

Panama City Tocumen Intl

jue. 3/5

3:15 pm-10:28 pm

1 stop8h 13m

$775

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

mar. 3/10

4:20 pm-12:40 pm

2 stops20h 20m

Panama City Tocumen Intl

mié. 3/18

3:10 pm-9:43 am

2 stops18h 33m

$779

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

mar. 4/28

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

jue. 5/7

2:20 pm-9:20 am

1 stop19h 00m

$787

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

lun. 3/2

4:21 pm-1:40 pm

2 stops20h 19m

Panama City Tocumen Intl

lun. 3/9

3:10 pm-9:43 am

2 stops18h 33m

$799

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Houston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, January is the cheapest month to fly from Houston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $788. If you’re not able to fly to Panama City in January, then March is your next best option. Flight prices from Houston to Panama City during March average around $854.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Houston to Panama City during this time can be as low as $886. Try not to purchase tickets in the morning because they tend to be around $896. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Houston to Panama City Tocumen Intl flight route?

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $903 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Houston for as low as $726 on momondo.

What cabin class options are available on Houston to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Houston to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Panama City

Fastest flight time

4h 11m

Direct flights

Every day

Airports in Panama City

1 airport
The fastest flight from Houston to Panama City takes 4h 11m
Direct flights go from Houston to Panama City every day.
There is 1 airport in Panama City. From Houston there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • How far is Houston to Panama City Tocumen Intl by plane?

    Houston and Panama City Tocumen Intl are 1762.1 mi apart from one another. A reasonable flight in good conditions will take 4h 11m.

  • When did momondo last update prices for flights from Houston to Panama City Tocumen Intl Airport?

    Prices for flights from Houston to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Houston to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Houston to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Panama City

Compare and see reviews for airlines that fly from Houston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $555Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $738Free CancellationRating
7.4
9,199 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Houston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Houston to Panama City with flexible booking policies on momondo?

Flights from Houston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Houston.

I’m not ready to book a flight from Houston to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Houston are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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