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Cheap flights from Houston to Panama City from $263

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Panama City departing on 9/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Houston to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:37 pm - 8:06 am
IAH
-
PTY
11h 29m
1 stop
Multiple Airlines Logo
3:10 pm - 9:54 am
PTY
-
IAH
18h 44m
2 stops
$530Multiple Airlines
Tue, Aug 11 - Tue, Aug 18
Multiple Airlines Logo
10:49 am - 7:20 pm
IAH
-
PTY
8h 31m
1 stop
Multiple Airlines Logo
3:10 pm - 9:54 am
PTY
-
IAH
18h 44m
2 stops
$533Multiple Airlines
Tue, Aug 18 - Tue, Sep 1
Multiple Airlines Logo
8:37 pm - 8:06 am
IAH
-
PTY
11h 29m
1 stop
Multiple Airlines Logo
3:10 pm - 11:53 am
PTY
-
IAH
20h 43m
2 stops
$534Multiple Airlines
Wed, Aug 12 - Fri, Aug 21
Multiple Airlines Logo
8:37 pm - 8:06 am
IAH
-
PTY
11h 29m
1 stop
Multiple Airlines Logo
9:33 pm - 8:24 am
PTY
-
IAH
10h 51m
1 stop
$542Multiple Airlines
Tue, Aug 4 - Fri, Aug 14
Delta Logo
6:00 am - 12:58 pm
HOU
-
PTY
6h 58m
1 stop
Delta Logo
2:23 pm - 10:40 pm
PTY
-
HOU
8h 17m
1 stop
$855Delta
Wed, Sep 16 - Mon, Sep 28
American Airlines Logo
12:46 pm - 12:14 pm
HOU
-
PTY
23h 28m
2 stops
American Airlines Logo
1:14 pm - 12:16 pm
PTY
-
HOU
23h 02m
2 stops
$859American Airlines
Tue, Jul 21 - Tue, Jul 28
Delta Logo
6:00 am - 2:05 pm
HOU
-
PTY
7h 05m
1 stop
Delta Logo
3:30 pm - 9:26 am
PTY
-
HOU
18h 56m
1 stop
$868Delta
Mon, Nov 23 - Mon, Dec 7
American Airlines Logo
12:46 pm - 12:14 pm
HOU
-
PTY
23h 28m
2 stops
American Airlines Logo
1:39 pm - 11:44 am
PTY
-
HOU
22h 05m
2 stops
$884American Airlines
Sat, Aug 1 - Thu, Aug 13
Delta Logo
6:00 am - 2:05 pm
HOU
-
PTY
7h 05m
1 stop
Delta Logo
3:30 pm - 9:26 am
PTY
-
HOU
18h 56m
1 stop
$893Delta
Mon, Nov 23 - Sun, Dec 13
American Airlines Logo
8:22 pm - 2:00 pm
HOU
-
PTY
17h 38m
2 stops
American Airlines Logo
3:35 pm - 8:59 am
PTY
-
HOU
17h 24m
2 stops
$909American Airlines
Sat, Oct 10 - Sat, Oct 24

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Avianca flights from Houston to Panama City

Our best Avianca deals on Houston to Panama City flight tickets
Avianca
Jul 2
IAH5:45 pmHouston George Bush Intcntl
8h 10m
1 stop
PTY1:55 amPanama City Tocumen Intl
Jul 16
PTY5:30 amPanama City Tocumen Intl
6h 35m
1 stop
IAH12:05 pmHouston George Bush Intcntl
$763
Avianca
Jul 5
IAH2:05 pmHouston George Bush Intcntl
11h 50m
1 stop
PTY1:55 amPanama City Tocumen Intl
Jul 19
PTY5:55 pmPanama City Tocumen Intl
18h 10m
2 stops
IAH12:05 pmHouston George Bush Intcntl
$779
Avianca
Jul 6
IAH5:45 pmHouston George Bush Intcntl
8h 10m
1 stop
PTY1:55 amPanama City Tocumen Intl
Jul 10
PTY5:30 amPanama City Tocumen Intl
10h 40m
1 stop
IAH4:10 pmHouston George Bush Intcntl
$793

American Airlines flights from Houston to Panama City

Our best American Airlines deals on Houston to Panama City flight tickets
American Airlines
Jul 21
HOU12:46 pmHouston Hobby
23h 28m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Jul 28
PTY1:14 pmPanama City Tocumen Intl
23h 02m
2 stops
HOU12:16 pmHouston Hobby
$859
American Airlines
Aug 1
HOU12:46 pmHouston Hobby
23h 28m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Aug 13
PTY1:39 pmPanama City Tocumen Intl
22h 05m
2 stops
HOU11:44 amHouston Hobby
$884
American Airlines
Jul 9
HOU4:14 pmHouston Hobby
20h 00m
2 stops
PTY12:14 pmPanama City Tocumen Intl
Jul 23
PTY1:14 pmPanama City Tocumen Intl
20h 34m
2 stops
HOU9:48 amHouston Hobby
$934

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Houston to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 8/11

8:37 pm-8:06 am

1 stop11h 29m

Panama City Tocumen Intl

Tue 8/18

3:10 pm-9:54 am

2 stops18h 44m

$530

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 8/18

10:49 am-7:20 pm

1 stop8h 31m

Panama City Tocumen Intl

Tue 9/1

3:10 pm-9:54 am

2 stops18h 44m

$533

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Wed 8/12

8:37 pm-8:06 am

1 stop11h 29m

Panama City Tocumen Intl

Fri 8/21

3:10 pm-11:53 am

2 stops20h 43m

$534

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Tue 8/4

8:37 pm-8:06 am

1 stop11h 29m

Panama City Tocumen Intl

Fri 8/14

9:33 pm-8:24 am

1 stop10h 51m

$542
Quickest round-trip

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Wed 9/16

6:00 am-12:58 pm

1 stop6h 58m

Panama City Tocumen Intl

Mon 9/28

2:23 pm-10:40 pm

1 stop8h 17m

$855

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 7/21

12:46 pm-12:14 pm

2 stops23h 28m

Panama City Tocumen Intl

Tue 7/28

1:14 pm-12:16 pm

2 stops23h 02m

$859

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Mon 11/23

6:00 am-2:05 pm

1 stop7h 05m

Panama City Tocumen Intl

Mon 12/7

3:30 pm-9:26 am

1 stop18h 56m

$868

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Sat 8/1

12:46 pm-12:14 pm

2 stops23h 28m

Panama City Tocumen Intl

Thu 8/13

1:39 pm-11:44 am

2 stops22h 05m

$884

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Mon 11/23

6:00 am-2:05 pm

1 stop7h 05m

Panama City Tocumen Intl

Sun 12/13

3:30 pm-9:26 am

1 stop18h 56m

$893

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Sat 10/10

8:22 pm-2:00 pm

2 stops17h 38m

Panama City Tocumen Intl

Sat 10/24

3:35 pm-8:59 am

2 stops17h 24m

$909

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Houston to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Houston and Panama City?

What is the cheapest month to fly to Panama City?

In general, July is the cheapest month to fly from Houston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $209. If you’re not able to fly to Panama City in July, then April is your next best option. Flight prices from Houston to Panama City during April average around $452.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Houston to Panama City during this time can be as low as $881. Try not to purchase tickets in the morning because they tend to be around $927. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Houston to Panama City Tocumen Intl flight route?

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston - Panama City Tocumen Intl flight prices

What cabin class options are available on Houston to Panama City flights?

There are 3 cabin classes available to choose from on Houston to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Panama City

Fastest flight time

4h 11m

Direct flights

Every day

Airports in Panama City

1 airport
The fastest flight from Houston to Panama City takes 4h 11m
Direct flights go from Houston to Panama City every day.
There is 1 airport in Panama City. From Houston there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from Houston to Panama City

  • How far is Houston to Panama City Tocumen Intl by plane?

    Houston and Panama City Tocumen Intl are 1762.1 mi apart from one another. A reasonable flight in good conditions will take 4h 11m.

  • When did momondo last update prices for flights from Houston to Panama City Tocumen Intl Airport?

    Prices for flights from Houston to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Houston to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Houston to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Houston to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Panama City

Compare and see reviews for airlines that fly from Houston to Panama City with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $543Free CancellationRating
7.1
3,003 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $559Free CancellationRating
7.6
1,568 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $760Free CancellationRating
7.4
9,878 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Houston to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Houston to Panama City with flexible booking policies on momondo?

Flights from Houston to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Houston to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Houston.

I’m not ready to book a flight from Houston to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Houston are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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