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Cheap flights from Guatemala City to Santiago from $238

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guatemala City to Santiago departing on 5/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Guatemala City to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
1:55 pm - 4:45 am
GUA
-
SCL
12h 50m
1 stop
Avianca Logo
12:30 am - 1:00 pm
SCL
-
GUA
14h 30m
1 stop
$468Avianca
Sun, Apr 19 - Mon, Apr 27
Copa Airlines Logo
7:12 am - 2:20 am
GUA
-
SCL
17h 08m
1 stop
Copa Airlines Logo
4:17 am - 10:46 pm
SCL
-
GUA
20h 29m
1 stop
$471Copa Airlines
Mon, Apr 20 - Fri, Apr 24
Copa Airlines Logo
4:24 am - 3:17 am
GUA
-
SCL
19h 53m
1 stop
Copa Airlines Logo
11:25 am - 11:10 pm
SCL
-
GUA
13h 45m
1 stop
$487Copa Airlines
Thu, Mar 19 - Fri, Apr 10
Copa Airlines Logo
10:34 am - 11:49 pm
GUA
-
SCL
10h 15m
1 stop
Copa Airlines Logo
1:38 am - 9:40 pm
SCL
-
GUA
23h 02m
2 stops
$496Copa Airlines
Fri, Mar 13 - Mon, Mar 16
Avianca Logo
9:30 am - 5:30 am
GUA
-
SCL
17h 00m
1 stop
Avianca Logo
1:35 am - 1:00 pm
SCL
-
GUA
14h 25m
1 stop
$507Avianca
Sat, Mar 14 - Fri, Mar 20
Avianca Logo
1:55 pm - 4:45 am
GUA
-
SCL
12h 50m
1 stop
Avianca Logo
12:30 am - 1:00 pm
SCL
-
GUA
14h 30m
1 stop
$508Avianca
Fri, May 1 - Sat, May 16
Copa Airlines Logo
2:26 am - 11:49 pm
GUA
-
SCL
18h 23m
1 stop
Copa Airlines Logo
5:44 am - 7:52 pm
SCL
-
GUA
17h 08m
1 stop
$522Copa Airlines
Fri, Mar 13 - Sat, Mar 21
Avianca Logo
7:00 am - 4:45 am
GUA
-
SCL
19h 45m
2 stops
Avianca Logo
6:40 am - 1:40 am
SCL
-
GUA
21h 00m
1 stop
$528Avianca
Fri, May 1 - Sun, May 17
Avianca Logo
7:00 am - 4:45 am
GUA
-
SCL
19h 45m
2 stops
Avianca Logo
6:40 am - 1:00 pm
SCL
-
GUA
32h 20m
1 stop
$530Avianca
Fri, May 1 - Sun, May 17
Copa Airlines Logo
10:34 am - 3:58 am
GUA
-
SCL
14h 24m
1 stop
Copa Airlines Logo
5:21 am - 10:39 pm
SCL
-
GUA
20h 18m
1 stop
$533Copa Airlines
Sat, Mar 14 - Sat, Mar 21

Avianca flights from Guatemala City to Santiago

Our best Avianca deals on Guatemala City to Santiago flight tickets
Avianca
Apr 19
GUA1:55 pmGuatemala City La Aurora
12h 50m
1 stop
SCL4:45 amSantiago Arturo Merino Benitez
Apr 27
SCL12:30 amSantiago Arturo Merino Benitez
14h 30m
1 stop
GUA1:00 pmGuatemala City La Aurora
$468
Avianca
Mar 14
GUA9:30 amGuatemala City La Aurora
17h 00m
1 stop
SCL5:30 amSantiago Arturo Merino Benitez
Mar 20
SCL1:35 amSantiago Arturo Merino Benitez
14h 25m
1 stop
GUA1:00 pmGuatemala City La Aurora
$507
Avianca
May 1
GUA1:55 pmGuatemala City La Aurora
22h 20m
1 stop
SCL2:15 pmSantiago Arturo Merino Benitez
May 17
SCL6:40 amSantiago Arturo Merino Benitez
32h 20m
1 stop
GUA1:00 pmGuatemala City La Aurora
$508

Copa Airlines flights from Guatemala City to Santiago

Our best Copa Airlines deals on Guatemala City to Santiago flight tickets
Copa Airlines
Apr 20
GUA6:24 amGuatemala City La Aurora
18h 36m
2 stops
SCL3:00 amSantiago Arturo Merino Benitez
Apr 24
SCL11:25 amSantiago Arturo Merino Benitez
12h 16m
2 stops
GUA9:41 pmGuatemala City La Aurora
$471
Copa Airlines
Mar 19
GUA6:24 amGuatemala City La Aurora
10h 56m
2 stops
SCL8:20 pmSantiago Arturo Merino Benitez
Apr 10
SCL11:25 amSantiago Arturo Merino Benitez
13h 21m
1 stop
GUA10:46 pmGuatemala City La Aurora
$487
Copa Airlines
Mar 13
GUA10:34 amGuatemala City La Aurora
10h 15m
1 stop
SCL11:49 pmSantiago Arturo Merino Benitez
Mar 16
SCL1:38 amSantiago Arturo Merino Benitez
23h 02m
2 stops
GUA9:40 pmGuatemala City La Aurora
$496

momondo Fare Finder

 
Customize your flight search to find flights from Guatemala City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Guatemala City to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sun 4/19

1:55 pm-4:45 am

1 stop12h 50m

Santiago Arturo Merino Benitez

Mon 4/27

12:30 am-1:00 pm

1 stop14h 30m

$468

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 4/20

7:12 am-2:20 am

1 stop17h 08m

Santiago Arturo Merino Benitez

Fri 4/24

4:17 am-10:46 pm

1 stop20h 29m

$471

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 3/19

4:24 am-3:17 am

1 stop19h 53m

Santiago Arturo Merino Benitez

Fri 4/10

11:25 am-11:10 pm

1 stop13h 45m

$487

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Fri 3/13

10:34 am-11:49 pm

1 stop10h 15m

Santiago Arturo Merino Benitez

Mon 3/16

1:38 am-9:40 pm

2 stops23h 02m

$496

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sat 3/14

9:30 am-5:30 am

1 stop17h 00m

Santiago Arturo Merino Benitez

Fri 3/20

1:35 am-1:00 pm

1 stop14h 25m

$507

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Fri 5/1

1:55 pm-4:45 am

1 stop12h 50m

Santiago Arturo Merino Benitez

Sat 5/16

12:30 am-1:00 pm

1 stop14h 30m

$508

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Fri 3/13

2:26 am-11:49 pm

1 stop18h 23m

Santiago Arturo Merino Benitez

Sat 3/21

5:44 am-7:52 pm

1 stop17h 08m

$522

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Fri 5/1

7:00 am-4:45 am

2 stops19h 45m

Santiago Arturo Merino Benitez

Sun 5/17

6:40 am-1:40 am

1 stop21h 00m

$528

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Fri 5/1

7:00 am-4:45 am

2 stops19h 45m

Santiago Arturo Merino Benitez

Sun 5/17

6:40 am-1:00 pm

1 stop32h 20m

$530

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sat 3/14

10:34 am-3:58 am

1 stop14h 24m

Santiago Arturo Merino Benitez

Sat 3/21

5:21 am-10:39 pm

1 stop20h 18m

$533

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Guatemala City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Guatemala City and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Guatemala City to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $494. If you don’t want to visit Santiago in May, then you should wait until August to fly from Guatemala City, when ticket prices are also cheap, with an average price of $526.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Guatemala City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $551 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Guatemala City for as low as $499 on momondo.

Can stopping save me money on Guatemala City to Santiago flights?

You could potentially save up to 12% on your flight if you consider stops on a Guatemala City to Santiago flight.

How have Guatemala City to Santiago flight prices changed over time?

As of February 2026, prices for Guatemala City to Santiago flights are approximately 38% more expensive when compared to flights at the same time last year.

When to book flights from Guatemala City to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Guatemala City to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guatemala City to Santiago (GUA to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guatemala City to Santiago

Fastest flight time

10h 08m

Direct flights

None
The fastest flight from Guatemala City to Santiago takes 10h 08m
There are no direct flights from Guatemala City to Santiago. There are no popular flight routes from Guatemala City to Santiago.
Search flight deals

  • How far is Guatemala City La Aurora to Santiago Arturo Merino Benitez by plane?

    The distance between Guatemala City La Aurora and Santiago Arturo Merino Benitez is about 3568.3 mi. By plane, this route typically takes 10h 08m.

  • When did momondo last update prices for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Guatemala City to Santiago?

Best airlines flying from Guatemala City to Santiago

Compare and see reviews for airlines that fly from Guatemala City to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $279Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
AviancaPriceFrom $407Free CancellationRating
6.5
2,498 reviews
Search Avianca flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
Valle Nevado
San Fernando
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Guatemala City to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Guatemala City to Santiago for you.

Can I find flights from Guatemala City to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Guatemala City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Guatemala City to Santiago?

Once all potential Guatemala City to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Guatemala City to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Guatemala City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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