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Cheap flights from Guatemala City to Santiago from $268

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guatemala City to Santiago departing on 3/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Guatemala City to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
9:40 pm - 12:30 amGUA-SCL
23h 50m2 stops
Avianca Logo
4:25 pm - 1:00 pmSCL-GUA
23h 35m1 stop
$484Avianca
Find Deal
Thu, Nov 20 - Mon, Nov 24
Avianca Logo
9:40 pm - 12:30 amGUA-SCL
23h 50m2 stops
Avianca Logo
7:25 am - 7:35 amSCL-GUA
27h 10m2 stops
$486Avianca
Find Deal
Thu, Nov 6 - Mon, Nov 17
Avianca Logo
9:40 pm - 12:30 amGUA-SCL
23h 50m2 stops
Avianca Logo
7:25 am - 7:35 amSCL-GUA
27h 10m2 stops
$492Avianca
Find Deal
Thu, Nov 20 - Mon, Nov 24
Avianca Logo
1:55 pm - 5:30 amGUA-SCL
12h 35m1 stop
Avianca Logo
7:25 am - 5:40 pmSCL-GUA
13h 15m1 stop
$499Avianca
Find Deal
Tue, Nov 4 - Tue, Nov 11
Copa Airlines Logo
5:39 am - 6:01 amGUA-SCL
21h 22m2 stops
Copa Airlines Logo
3:23 am - 11:50 amSCL-GUA
11h 27m1 stop
$502Copa Airlines
Find Deal
Tue, Nov 4 - Mon, Nov 10
Avianca Logo
9:45 pm - 1:25 pmGUA-SCL
13h 40m2 stops
Avianca Logo
11:55 pm - 3:40 pmSCL-GUA
17h 45m1 stop
$507Avianca
Find Deal
Sun, Apr 19 - Tue, Apr 28
Copa Airlines Logo
5:39 am - 11:41 pmGUA-SCL
15h 02m2 stops
Copa Airlines Logo
3:23 am - 9:38 pmSCL-GUA
21h 15m2 stops
$510Copa Airlines
Find Deal
Tue, Nov 4 - Thu, Nov 13
Avianca Logo
1:55 pm - 5:30 amGUA-SCL
12h 35m1 stop
Avianca Logo
4:25 pm - 1:40 amSCL-GUA
12h 15m1 stop
$511Avianca
Find Deal
Thu, Nov 20 - Mon, Nov 24
Copa Airlines Logo
5:39 am - 6:01 amGUA-SCL
21h 22m2 stops
Copa Airlines Logo
5:12 am - 9:38 pmSCL-GUA
19h 26m2 stops
$519Copa Airlines
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Sun, Nov 9 - Thu, Nov 13
Multiple Airlines Logo
4:21 am - 8:21 pmGUA-SCL
13h 00m1 stop
Multiple Airlines Logo
4:25 pm - 1:00 pmSCL-GUA
23h 35m1 stop
$532Multiple Airlines
Find Deal
Wed, Nov 19 - Mon, Nov 24

Avianca flights from Guatemala City to Santiago

Our best Avianca deals on Guatemala City to Santiago flight tickets
Avianca
Nov 20
GUA9:40 pmGuatemala City La Aurora
23h 50m
2 stops
SCL12:30 amSantiago Arturo Merino Benitez
Nov 24
SCL4:25 pmSantiago Arturo Merino Benitez
23h 35m
1 stop
GUA1:00 pmGuatemala City La Aurora
$484
Find similar
Avianca
Nov 6
GUA9:40 pmGuatemala City La Aurora
23h 50m
2 stops
SCL12:30 amSantiago Arturo Merino Benitez
Nov 17
SCL7:25 amSantiago Arturo Merino Benitez
27h 10m
2 stops
GUA7:35 amGuatemala City La Aurora
$486
Find similar
Avianca
Nov 20
GUA9:40 pmGuatemala City La Aurora
23h 50m
2 stops
SCL12:30 amSantiago Arturo Merino Benitez
Nov 24
SCL7:25 amSantiago Arturo Merino Benitez
27h 10m
2 stops
GUA7:35 amGuatemala City La Aurora
$492
Find similar

Copa Airlines flights from Guatemala City to Santiago

Our best Copa Airlines deals on Guatemala City to Santiago flight tickets
Copa Airlines
Nov 4
GUA5:39 amGuatemala City La Aurora
15h 02m
2 stops
SCL11:41 pmSantiago Arturo Merino Benitez
Nov 10
SCL3:23 amSantiago Arturo Merino Benitez
21h 15m
2 stops
GUA9:38 pmGuatemala City La Aurora
$502
Find similar
Copa Airlines
Nov 4
GUA5:39 amGuatemala City La Aurora
15h 02m
2 stops
SCL11:41 pmSantiago Arturo Merino Benitez
Nov 13
SCL3:23 amSantiago Arturo Merino Benitez
21h 15m
2 stops
GUA9:38 pmGuatemala City La Aurora
$510
Find similar
Copa Airlines
Nov 9
GUA5:39 amGuatemala City La Aurora
21h 22m
2 stops
SCL6:01 amSantiago Arturo Merino Benitez
Nov 13
SCL5:12 amSantiago Arturo Merino Benitez
19h 26m
2 stops
GUA9:38 pmGuatemala City La Aurora
$519
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Guatemala City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Guatemala City to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 11/20

9:40 pm-12:30 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Mon 11/24

4:25 pm-1:00 pm

1 stop23h 35m

$484

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 11/6

9:40 pm-12:30 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Mon 11/17

7:25 am-7:35 am

2 stops27h 10m

$486

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 11/20

9:40 pm-12:30 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Mon 11/24

7:25 am-7:35 am

2 stops27h 10m

$492

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Tue 11/4

1:55 pm-5:30 am

1 stop12h 35m

Santiago Arturo Merino Benitez

Tue 11/11

7:25 am-5:40 pm

1 stop13h 15m

$499

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Tue 11/4

5:39 am-6:01 am

2 stops21h 22m

Santiago Arturo Merino Benitez

Mon 11/10

3:23 am-11:50 am

1 stop11h 27m

$502

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sun 4/19

9:45 pm-1:25 pm

2 stops13h 40m

Santiago Arturo Merino Benitez

Tue 4/28

11:55 pm-3:40 pm

1 stop17h 45m

$507

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Tue 11/4

5:39 am-11:41 pm

2 stops15h 02m

Santiago Arturo Merino Benitez

Thu 11/13

3:23 am-9:38 pm

2 stops21h 15m

$510

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 11/20

1:55 pm-5:30 am

1 stop12h 35m

Santiago Arturo Merino Benitez

Mon 11/24

4:25 pm-1:40 am

1 stop12h 15m

$511

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sun 11/9

5:39 am-6:01 am

2 stops21h 22m

Santiago Arturo Merino Benitez

Thu 11/13

5:12 am-9:38 pm

2 stops19h 26m

$519

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Wed 11/19

4:21 am-8:21 pm

1 stop13h 00m

Santiago Arturo Merino Benitez

Mon 11/24

4:25 pm-1:00 pm

1 stop23h 35m

$532

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Guatemala City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Guatemala City and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from Guatemala City to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $485. If you don’t want to visit Santiago in May, then you should wait until August to fly from Guatemala City, when ticket prices are also cheap, with an average price of $501.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Saturday when prices can be found for as low as $492. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Thursday is $629.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Guatemala City to Santiago when you can find flight prices for as low as $510. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $752 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Guatemala City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $563 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Guatemala City for as low as $489 on momondo.

Can stopping save me money on Guatemala City to Santiago flights?

You could potentially save up to 8% on your flight if you consider stops on a Guatemala City to Santiago flight.

How have Guatemala City to Santiago flight prices changed over time?

As of October 2025, prices for Guatemala City to Santiago flights are approximately 15% more expensive when compared to flights at the same time last year.

When to book flights from Guatemala City to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Guatemala City to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guatemala City to Santiago (GUA to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guatemala City to Santiago

Direct flights

None
There are no direct flights from Guatemala City to Santiago. There are no popular flight routes from Guatemala City to Santiago.
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  • How far is Guatemala City La Aurora to Santiago Arturo Merino Benitez by plane?

    The distance between Guatemala City La Aurora and Santiago Arturo Merino Benitez is about 3568.3 mi. By plane, this route typically takes 10h 46m.

  • When did momondo last update prices for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Guatemala City to Santiago?

Best airlines flying from Guatemala City to Santiago

Compare and see reviews for airlines that fly from Guatemala City to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $384Free CancellationRating
6.6
2,460 reviews
Search Avianca flights
Copa AirlinesPriceFrom $410Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Guatemala City to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Guatemala City to Santiago for you.

Can I find flights from Guatemala City to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Guatemala City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Guatemala City to Santiago?

Once all potential Guatemala City to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Guatemala City to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Guatemala City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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