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Cheap flights from Guatemala City to Santiago from $273

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guatemala City to Santiago departing on 10/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Guatemala City to Santiago

Cheap round-trip flights

Logo
4:35 pm - 10:10 pmGUA-SCL
26h 35m2 stops
Logo
12:55 am - 3:40 pmSCL-GUA
17h 45m1 stop
$530
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Mon, Oct 6 - Tue, Oct 14
Avianca Logo
4:10 pm - 5:15 amGUA-SCL
10h 05m1 stop
Avianca Logo
12:55 am - 3:14 pmSCL-GUA
17h 19m1 stop
$535Avianca
Find Deal
Thu, Sep 25 - Fri, Oct 3
Logo
7:50 am - 6:00 amGUA-SCL
19h 10m3 stops
Logo
7:10 am - 3:40 pmSCL-GUA
11h 30m1 stop
$538
Find Deal
Mon, Oct 6 - Wed, Oct 15
Avianca Logo
7:50 am - 10:30 pmGUA-SCL
12h 40m2 stops
Avianca Logo
11:55 pm - 3:14 pmSCL-GUA
17h 19m1 stop
$540Avianca
Find Deal
Mon, Sep 1 - Fri, Sep 5
Avianca Logo
9:45 pm - 2:25 pmGUA-SCL
13h 40m2 stops
Avianca Logo
7:10 am - 5:15 pmSCL-GUA
13h 05m1 stop
$543Avianca
Find Deal
Thu, Sep 25 - Sat, Oct 4
Avianca Logo
7:50 am - 5:15 amGUA-SCL
18h 25m2 stops
Avianca Logo
12:55 am - 5:55 pmSCL-GUA
20h 00m2 stops
$546Avianca
Find Deal
Mon, Oct 13 - Fri, Oct 24
Avianca Logo
9:40 am - 5:15 amGUA-SCL
16h 35m1 stop
Avianca Logo
7:10 am - 5:15 pmSCL-GUA
13h 05m1 stop
$549Avianca
Find Deal
Thu, Sep 11 - Thu, Sep 18
Copa Airlines Logo
5:39 am - 12:32 amGUA-SCL
15h 53m2 stops
Copa Airlines Logo
1:16 am - 8:55 amSCL-GUA
10h 39m1 stop
$551Copa Airlines
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Tue, Jan 13 - Thu, Feb 26
Copa Airlines Logo
4:21 am - 8:21 pmGUA-SCL
13h 00m1 stop
Copa Airlines Logo
3:23 am - 9:38 pmSCL-GUA
21h 15m2 stops
$559Copa Airlines
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Mon, Nov 3 - Mon, Nov 10
Copa Airlines Logo
5:39 am - 11:40 pmGUA-SCL
15h 01m2 stops
Copa Airlines Logo
3:35 am - 9:36 pmSCL-GUA
21h 01m2 stops
$567Copa Airlines
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Sat, Oct 11 - Tue, Oct 14

Avianca flights from Guatemala City to Santiago

Our best Avianca deals on Guatemala City to Santiago flight tickets
Avianca
Aug 16
GUA6:35 amGuatemala City La Aurora
13h 55m
1 stop
SCL10:30 pmSantiago Arturo Merino Benitez
Aug 18
SCL11:55 pmSantiago Arturo Merino Benitez
17h 19m
1 stop
GUA3:14 pmGuatemala City La Aurora
$535
Find similar
Avianca
Sep 1
GUA7:50 amGuatemala City La Aurora
12h 40m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
Sep 5
SCL11:55 pmSantiago Arturo Merino Benitez
17h 19m
1 stop
GUA3:14 pmGuatemala City La Aurora
$540
Find similar
Avianca
Aug 16
GUA9:45 pmGuatemala City La Aurora
13h 40m
2 stops
SCL1:25 pmSantiago Arturo Merino Benitez
Aug 18
SCL2:30 pmSantiago Arturo Merino Benitez
12h 55m
1 stop
GUA1:25 amGuatemala City La Aurora
$543
Find similar

Copa Airlines flights from Guatemala City to Santiago

Our best Copa Airlines deals on Guatemala City to Santiago flight tickets
Copa Airlines
Jan 13
GUA5:39 amGuatemala City La Aurora
15h 53m
2 stops
SCL12:32 amSantiago Arturo Merino Benitez
Feb 26
SCL1:16 amSantiago Arturo Merino Benitez
10h 39m
1 stop
GUA8:55 amGuatemala City La Aurora
$551
Find similar
Copa Airlines
Aug 16
GUA5:39 amGuatemala City La Aurora
11h 45m
2 stops
SCL7:24 pmSantiago Arturo Merino Benitez
Aug 22
SCL2:26 amSantiago Arturo Merino Benitez
21h 11m
2 stops
GUA9:37 pmGuatemala City La Aurora
$559
Find similar
Copa Airlines
Oct 11
GUA5:39 amGuatemala City La Aurora
15h 01m
2 stops
SCL11:40 pmSantiago Arturo Merino Benitez
Oct 14
SCL3:35 amSantiago Arturo Merino Benitez
21h 01m
2 stops
GUA9:36 pmGuatemala City La Aurora
$567
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Guatemala City to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Guatemala City to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 10/6

4:35 pm-10:10 pm

2 stops26h 35m

Santiago Arturo Merino Benitez

Tue 10/14

12:55 am-3:40 pm

1 stop17h 45m

$530

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 9/25

4:10 pm-5:15 am

1 stop10h 05m

Santiago Arturo Merino Benitez

Fri 10/3

12:55 am-3:14 pm

1 stop17h 19m

$535

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 10/6

7:50 am-6:00 am

3 stops19h 10m

Santiago Arturo Merino Benitez

Wed 10/15

7:10 am-3:40 pm

1 stop11h 30m

$538

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 9/1

7:50 am-10:30 pm

2 stops12h 40m

Santiago Arturo Merino Benitez

Fri 9/5

11:55 pm-3:14 pm

1 stop17h 19m

$540

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 9/25

9:45 pm-2:25 pm

2 stops13h 40m

Santiago Arturo Merino Benitez

Sat 10/4

7:10 am-5:15 pm

1 stop13h 05m

$543

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 10/13

7:50 am-5:15 am

2 stops18h 25m

Santiago Arturo Merino Benitez

Fri 10/24

12:55 am-5:55 pm

2 stops20h 00m

$546

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Thu 9/11

9:40 am-5:15 am

1 stop16h 35m

Santiago Arturo Merino Benitez

Thu 9/18

7:10 am-5:15 pm

1 stop13h 05m

$549

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Tue 1/13

5:39 am-12:32 am

2 stops15h 53m

Santiago Arturo Merino Benitez

Thu 2/26

1:16 am-8:55 am

1 stop10h 39m

$551

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Mon 11/3

4:21 am-8:21 pm

1 stop13h 00m

Santiago Arturo Merino Benitez

Mon 11/10

3:23 am-9:38 pm

2 stops21h 15m

$559

Guatemala CitySantiago

GUA - SCL

GUASCL

Guatemala City La Aurora

Sat 10/11

5:39 am-11:40 pm

2 stops15h 01m

Santiago Arturo Merino Benitez

Tue 10/14

3:35 am-9:36 pm

2 stops21h 01m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from Guatemala City to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Guatemala City and Santiago?

What is the cheapest month to fly to Santiago?

In general, August is the cheapest month to fly from Guatemala City to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $472. If you don’t want to visit Santiago in August, then you should wait until May to fly from Guatemala City, when ticket prices are also cheap, with an average price of $486.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Saturday when prices can be found for as low as $492. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Thursday is $629.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from Guatemala City to Santiago when you can find flight prices for as low as $510. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $752 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Guatemala City when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $554 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Guatemala City for as low as $448 on momondo.

How have Guatemala City to Santiago flight prices changed over time?

As of August 2025, prices for Guatemala City to Santiago flights are approximately 16% more expensive when compared to flights at the same time last year.

When to book flights from Guatemala City to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Guatemala City to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guatemala City to Santiago (GUA to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guatemala City to Santiago

Best Price Found

$273

Fastest flight time

10h 05m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from Guatemala City in the past 72 hours is $273. The best round-trip flight deal from Guatemala City to Santiago found on momondo in the last 72 hours is $530.
The fastest flight from Guatemala City to Santiago takes 10h 05m
There are no direct flights from Guatemala City to Santiago. Popular non-direct route for this connection is Guatemala City La Aurora Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Guatemala City La Aurora to Santiago Arturo Merino Benitez by plane?

    The distance between Guatemala City La Aurora and Santiago Arturo Merino Benitez is about 3568.3 mi. By plane, this route typically takes 10h 05m.

  • When did momondo last update prices for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Guatemala City La Aurora Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Guatemala City to Santiago?

Best airlines flying from Guatemala City to Santiago

Compare and see reviews for airlines that fly from Guatemala City to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $374Free CancellationRating
6.7
2,399 reviews
Search Avianca flights
Copa AirlinesPriceFrom $410Free CancellationRating
7.5
1,507 reviews
Search Copa Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Guatemala City to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Guatemala City to Santiago for you.

Can I find flights from Guatemala City to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Guatemala City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Guatemala City to Santiago?

Once all potential Guatemala City to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Guatemala City to Santiago right now. Can momondo alert me if prices change?

Price alerts on flights to Santiago from Guatemala City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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