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Cheap flights from Fort Myers to Santiago de los Caballeros from $251

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to Santiago de los Caballeros departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Fort Myers to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
6:00 am - 8:09 pmRSW-STI
13h 09m1 stop
JetBlue Logo
10:46 am - 11:48 pmSTI-RSW
14h 02m1 stop
$466JetBlue
Find Deal
Fri, Nov 21 - Fri, Nov 28
JetBlue Logo
2:10 pm - 12:04 amRSW-STI
9h 54m1 stop
JetBlue Logo
10:09 pm - 9:20 amSTI-RSW
11h 11m1 stop
$512JetBlue
Find Deal
Wed, Apr 1 - Fri, Apr 3
JetBlue Logo
7:10 pm - 2:54 amRSW-STI
7h 44m1 stop
JetBlue Logo
2:05 am - 11:20 amSTI-RSW
9h 15m1 stop
$526JetBlue
Find Deal
Wed, Apr 1 - Thu, Apr 2
Spirit Airlines Logo
12:15 pm - 12:22 pmRSW-STI
23h 07m2 stops
Spirit Airlines Logo
1:17 pm - 8:36 amSTI-RSW
20h 19m2 stops
$530Spirit Airlines
Find Deal
Fri, Nov 21 - Fri, Nov 28
Multiple Airlines Logo
3:18 pm - 12:22 pmRSW-STI
20h 04m3 stops
Multiple Airlines Logo
1:17 pm - 8:36 amSTI-RSW
20h 19m2 stops
$544Multiple Airlines
Find Deal
Fri, Nov 21 - Fri, Nov 28
Multiple Airlines Logo
3:18 pm - 12:22 pmRSW-STI
20h 04m3 stops
Multiple Airlines Logo
1:17 pm - 8:36 amSTI-RSW
20h 19m3 stops
$583Multiple Airlines
Find Deal
Fri, Nov 21 - Fri, Nov 28
American Airlines Logo
11:58 am - 8:03 pmRSW-STI
8h 05m2 stops
American Airlines Logo
7:00 am - 12:24 amSTI-RSW
17h 24m2 stops
$632American Airlines
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Wed, Apr 1 - Fri, Apr 3
Delta Logo
7:30 pm - 12:08 pmRSW-STI
16h 38m1 stop
Delta Logo
7:41 pm - 10:54 amSTI-RSW
15h 13m1 stop
$678Delta
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Wed, Apr 1 - Fri, Apr 3
Delta Logo
1:00 pm - 11:27 pmRSW-STI
10h 27m2 stops
Delta Logo
6:00 am - 6:22 pmSTI-RSW
12h 22m1 stop
$682Delta
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Wed, Apr 1 - Fri, Apr 3
American Airlines Logo
6:13 am - 3:45 pmRSW-STI
8h 32m2 stops
American Airlines Logo
8:10 am - 10:07 pmSTI-RSW
13h 57m3 stops
$2,577American Airlines
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Sun, Nov 30 - Wed, May 27

JetBlue flights from Fort Myers to Santiago de los Caballeros

Our best JetBlue deals on Fort Myers to Santiago de los Caballeros flight tickets
JetBlue
Nov 21
RSW6:00 amFort Myers SW Florida Intl
13h 09m
1 stop
STI8:09 pmSantiago de los Caballeros
Nov 28
STI10:46 amSantiago de los Caballeros
14h 02m
1 stop
RSW11:48 pmFort Myers SW Florida Intl
$466
Find similar
JetBlue
Apr 1
RSW2:10 pmFort Myers SW Florida Intl
9h 54m
1 stop
STI12:04 amSantiago de los Caballeros
Apr 3
STI10:09 pmSantiago de los Caballeros
11h 11m
1 stop
RSW9:20 amFort Myers SW Florida Intl
$512
Find similar
JetBlue
Apr 1
RSW7:10 pmFort Myers SW Florida Intl
7h 44m
1 stop
STI2:54 amSantiago de los Caballeros
Apr 2
STI2:05 amSantiago de los Caballeros
9h 15m
1 stop
RSW11:20 amFort Myers SW Florida Intl
$526
Find similar

American Airlines flights from Fort Myers to Santiago de los Caballeros

Our best American Airlines deals on Fort Myers to Santiago de los Caballeros flight tickets
American Airlines
Apr 1
RSW11:58 amFort Myers SW Florida Intl
8h 05m
2 stops
STI8:03 pmSantiago de los Caballeros
Apr 3
STI7:00 amSantiago de los Caballeros
17h 24m
2 stops
RSW12:24 amFort Myers SW Florida Intl
$632
Find similar
American Airlines
Nov 30
RSW6:13 amFort Myers SW Florida Intl
8h 32m
2 stops
STI3:45 pmSantiago de los Caballeros
May 27
STI8:10 amSantiago de los Caballeros
13h 57m
3 stops
RSW10:07 pmFort Myers SW Florida Intl
$2,577
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Fort Myers to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 11/21

6:00 am-8:09 pm

1 stop13h 09m

Santiago de los Caballeros

Fri 11/28

10:46 am-11:48 pm

1 stop14h 02m

$466

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 4/1

2:10 pm-12:04 am

1 stop9h 54m

Santiago de los Caballeros

Fri 4/3

10:09 pm-9:20 am

1 stop11h 11m

$512

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 4/1

7:10 pm-2:54 am

1 stop7h 44m

Santiago de los Caballeros

Thu 4/2

2:05 am-11:20 am

1 stop9h 15m

$526

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 11/21

12:15 pm-12:22 pm

2 stops23h 07m

Santiago de los Caballeros

Fri 11/28

1:17 pm-8:36 am

2 stops20h 19m

$530

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 11/21

3:18 pm-12:22 pm

3 stops20h 04m

Santiago de los Caballeros

Fri 11/28

1:17 pm-8:36 am

2 stops20h 19m

$544

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 11/21

3:18 pm-12:22 pm

3 stops20h 04m

Santiago de los Caballeros

Fri 11/28

1:17 pm-8:36 am

3 stops20h 19m

$583

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 4/1

11:58 am-8:03 pm

2 stops8h 05m

Santiago de los Caballeros

Fri 4/3

7:00 am-12:24 am

2 stops17h 24m

$632

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 4/1

7:30 pm-12:08 pm

1 stop16h 38m

Santiago de los Caballeros

Fri 4/3

7:41 pm-10:54 am

1 stop15h 13m

$678

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 4/1

1:00 pm-11:27 pm

2 stops10h 27m

Santiago de los Caballeros

Fri 4/3

6:00 am-6:22 pm

1 stop12h 22m

$682

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sun 11/30

6:13 am-3:45 pm

2 stops8h 32m

Santiago de los Caballeros

Wed 5/27

8:10 am-10:07 pm

3 stops13h 57m

$2,577

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Fort Myers to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Fort Myers SW Florida Intl to Santiago de los Caballeros?

JetBlue, Delta, and Spirit Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Santiago de los Caballeros

When to book flights from Fort Myers to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Fort Myers to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Fort Myers to Santiago de los Caballeros (RSW to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Santiago de los Caballeros

Direct flights

None
There are no direct flights from Fort Myers to Santiago de los Caballeros. There are no popular flight routes from Fort Myers to Santiago de los Caballeros.
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  • How far is Fort Myers SW Florida Intl to Santiago de los Caballeros by plane?

    A flight from Fort Myers SW Florida Intl to Santiago de los Caballeros will travel around 865.6 mi. By plane, this route typically takes 7h 19m.

  • When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport?

    Prices for flights from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport were last updated today.

  • How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Fort Myers.

Can I find flights from Fort Myers to Santiago de los Caballeros with flexible booking policies on momondo?

Flights from Fort Myers to Santiago de los Caballeros with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Fort Myers to Santiago de los Caballeros?

Once all potential Fort Myers to Santiago de los Caballeros flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Fort Myers to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Fort Myers to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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