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Cheap flights from Fort Myers to Santiago de los Caballeros from $388

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to Santiago de los Caballeros departing on 5/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Fort Myers to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
12:25 pm - 1:59 am
RSW
-
STI
13h 34m
1 stop
Delta Logo
8:59 pm - 11:27 am
STI
-
RSW
14h 28m
1 stop
$540Delta
Tue, Jun 9 - Tue, Jun 16
Delta Logo
6:45 am - 1:59 am
RSW
-
STI
19h 14m
2 stops
Delta Logo
8:59 pm - 2:45 pm
STI
-
RSW
17h 46m
2 stops
$545Delta
Tue, Jun 9 - Tue, Jun 16
Delta Logo
12:25 pm - 1:59 am
RSW
-
STI
13h 34m
1 stop
Delta Logo
8:59 pm - 11:27 am
STI
-
RSW
14h 28m
1 stop
$575Delta
Wed, Jun 10 - Wed, Jun 17
Delta Logo
12:25 pm - 1:59 am
RSW
-
STI
13h 34m
1 stop
Delta Logo
8:59 pm - 4:39 pm
STI
-
RSW
19h 40m
2 stops
$580Delta
Wed, Jun 10 - Wed, Jun 17
JetBlue Logo
12:41 pm - 9:02 pm
RSW
-
STI
8h 21m
1 stop
JetBlue Logo
1:17 am - 11:37 am
STI
-
RSW
10h 20m
1 stop
$650JetBlue
Fri, May 29 - Thu, Jun 11
American Airlines Logo
6:21 am - 2:44 pm
RSW
-
STI
32h 23m
2 stops
American Airlines Logo
3:44 pm - 3:09 pm
STI
-
RSW
23h 25m
2 stops
$691American Airlines
Sat, Jul 4 - Fri, Jul 24
JetBlue Logo
7:04 am - 9:02 pm
RSW
-
STI
13h 58m
1 stop
JetBlue Logo
6:00 am - 12:07 am
STI
-
RSW
18h 07m
1 stop
$693JetBlue
Fri, May 29 - Sun, Jun 14
Delta Logo
12:26 pm - 12:59 am
RSW
-
STI
12h 33m
1 stop
Delta Logo
8:59 pm - 4:39 pm
STI
-
RSW
19h 40m
2 stops
$715Delta
Fri, May 29 - Fri, Jun 12
American Airlines Logo
3:57 pm - 9:13 pm
RSW
-
STI
29h 16m
2 stops
American Airlines Logo
3:39 pm - 3:06 pm
STI
-
RSW
23h 27m
2 stops
$732American Airlines
Fri, May 29 - Fri, Jun 12
JetBlue Logo
7:04 am - 10:32 pm
RSW
-
STI
15h 28m
1 stop
JetBlue Logo
6:47 pm - 11:37 am
STI
-
RSW
16h 50m
2 stops
$781JetBlue
Fri, May 29 - Sun, Jun 14

Delta flights from Fort Myers to Santiago de los Caballeros

Our best Delta deals on Fort Myers to Santiago de los Caballeros flight tickets
Delta
Jun 9
RSW12:25 pmFort Myers SW Florida Intl
13h 34m
1 stop
STI1:59 amSantiago de los Caballeros
Jun 16
STI8:59 pmSantiago de los Caballeros
14h 28m
1 stop
RSW11:27 amFort Myers SW Florida Intl
$540
Delta
Jun 9
RSW6:45 amFort Myers SW Florida Intl
19h 14m
2 stops
STI1:59 amSantiago de los Caballeros
Jun 16
STI8:59 pmSantiago de los Caballeros
17h 46m
2 stops
RSW2:45 pmFort Myers SW Florida Intl
$545
Delta
Jun 10
RSW12:25 pmFort Myers SW Florida Intl
13h 34m
1 stop
STI1:59 amSantiago de los Caballeros
Jun 17
STI8:59 pmSantiago de los Caballeros
14h 28m
1 stop
RSW11:27 amFort Myers SW Florida Intl
$575

JetBlue flights from Fort Myers to Santiago de los Caballeros

Our best JetBlue deals on Fort Myers to Santiago de los Caballeros flight tickets
JetBlue
May 29
RSW12:41 pmFort Myers SW Florida Intl
8h 21m
1 stop
STI9:02 pmSantiago de los Caballeros
Jun 11
STI1:17 amSantiago de los Caballeros
10h 20m
1 stop
RSW11:37 amFort Myers SW Florida Intl
$650
JetBlue
May 29
RSW7:04 amFort Myers SW Florida Intl
13h 58m
1 stop
STI9:02 pmSantiago de los Caballeros
Jun 14
STI6:00 amSantiago de los Caballeros
18h 07m
1 stop
RSW12:07 amFort Myers SW Florida Intl
$693
JetBlue
May 29
RSW7:04 amFort Myers SW Florida Intl
15h 28m
1 stop
STI10:32 pmSantiago de los Caballeros
Jun 14
STI6:47 pmSantiago de los Caballeros
16h 50m
2 stops
RSW11:37 amFort Myers SW Florida Intl
$781

momondo Fare Finder

 
Customize your flight search to find flights from Fort Myers to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Tue 6/9

12:25 pm-1:59 am

1 stop13h 34m

Santiago de los Caballeros

Tue 6/16

8:59 pm-11:27 am

1 stop14h 28m

$540

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Tue 6/9

6:45 am-1:59 am

2 stops19h 14m

Santiago de los Caballeros

Tue 6/16

8:59 pm-2:45 pm

2 stops17h 46m

$545

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 6/10

12:25 pm-1:59 am

1 stop13h 34m

Santiago de los Caballeros

Wed 6/17

8:59 pm-11:27 am

1 stop14h 28m

$575

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 6/10

12:25 pm-1:59 am

1 stop13h 34m

Santiago de los Caballeros

Wed 6/17

8:59 pm-4:39 pm

2 stops19h 40m

$580
Quickest round-trip

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 5/29

12:41 pm-9:02 pm

1 stop8h 21m

Santiago de los Caballeros

Thu 6/11

1:17 am-11:37 am

1 stop10h 20m

$650

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sat 7/4

6:21 am-2:44 pm

2 stops32h 23m

Santiago de los Caballeros

Fri 7/24

3:44 pm-3:09 pm

2 stops23h 25m

$691

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 5/29

7:04 am-9:02 pm

1 stop13h 58m

Santiago de los Caballeros

Sun 6/14

6:00 am-12:07 am

1 stop18h 07m

$693

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 5/29

12:26 pm-12:59 am

1 stop12h 33m

Santiago de los Caballeros

Fri 6/12

8:59 pm-4:39 pm

2 stops19h 40m

$715

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 5/29

3:57 pm-9:13 pm

2 stops29h 16m

Santiago de los Caballeros

Fri 6/12

3:39 pm-3:06 pm

2 stops23h 27m

$732

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 5/29

7:04 am-10:32 pm

1 stop15h 28m

Santiago de los Caballeros

Sun 6/14

6:47 pm-11:37 am

2 stops16h 50m

$781

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Fort Myers to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Fort Myers SW Florida Intl to Santiago de los Caballeros?

JetBlue is the most popular carrier operating from Fort Myers SW Florida Intl to Santiago de los Caballeros

When to book flights from Fort Myers to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Fort Myers to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Fort Myers to Santiago de los Caballeros (RSW to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Santiago de los Caballeros

Fastest flight time

13h 34m

Direct flights

None
The fastest flight from Fort Myers to Santiago de los Caballeros takes 13h 34m
There are no direct flights from Fort Myers to Santiago de los Caballeros. There are no popular flight routes from Fort Myers to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Fort Myers to Santiago de los Caballeros

  • How far is Fort Myers SW Florida Intl to Santiago de los Caballeros by plane?

    A flight from Fort Myers SW Florida Intl to Santiago de los Caballeros will travel around 865.6 mi. By plane, this route typically takes 13h 34m.

  • When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport?

    Prices for flights from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport were last updated today.

  • How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Fort Myers.

Can I find flights from Fort Myers to Santiago de los Caballeros with flexible booking policies on momondo?

Flights from Fort Myers to Santiago de los Caballeros with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Fort Myers to Santiago de los Caballeros?

Once all potential Fort Myers to Santiago de los Caballeros flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Fort Myers to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Fort Myers to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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