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Cheap flights from Fort Myers to Santiago de los Caballeros from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to Santiago de los Caballeros departing on 2/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Fort Myers to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
1:47 pm - 1:49 am
RSW
-
STI
12h 02m
2 stops
Spirit Airlines Logo
3:43 pm - 7:39 pm
STI
-
RSW
27h 56m
3 stops
$510Spirit Airlines
Fri, Mar 13 - Fri, Mar 20
American Airlines Logo
7:35 pm - 9:13 pm
RSW
-
STI
25h 38m
2 stops
American Airlines Logo
7:00 am - 9:06 am
STI
-
RSW
26h 06m
2 stops
$521American Airlines
Mon, Jun 15 - Wed, Jul 15
Spirit Airlines Logo
8:34 pm - 1:49 am
RSW
-
STI
29h 15m
3 stops
Spirit Airlines Logo
3:43 pm - 3:05 pm
STI
-
RSW
23h 22m
3 stops
$528Spirit Airlines
Fri, Mar 13 - Fri, Mar 20
Spirit Airlines Logo
1:47 pm - 1:49 am
RSW
-
STI
12h 02m
2 stops
Spirit Airlines Logo
2:46 am - 3:05 pm
STI
-
RSW
12h 19m
2 stops
$535Spirit Airlines
Fri, Mar 13 - Thu, Mar 19
JetBlue Logo
7:09 pm - 1:47 am
RSW
-
STI
30h 38m
1 stop
JetBlue Logo
8:40 pm - 9:44 am
STI
-
RSW
13h 04m
1 stop
$628JetBlue
Fri, Mar 13 - Fri, Mar 20
Delta Logo
6:50 am - 12:30 am
RSW
-
STI
17h 40m
2 stops
Delta Logo
8:50 pm - 10:47 am
STI
-
RSW
13h 57m
1 stop
$633Delta
Mon, Jun 15 - Wed, Jul 15
JetBlue Logo
8:07 pm - 5:13 pm
RSW
-
STI
21h 06m
1 stop
JetBlue Logo
7:01 am - 10:50 pm
STI
-
RSW
15h 49m
1 stop
$649JetBlue
Mon, Jun 15 - Wed, Jul 15
JetBlue Logo
3:10 pm - 3:49 am
RSW
-
STI
12h 39m
1 stop
JetBlue Logo
8:30 am - 11:20 pm
STI
-
RSW
14h 50m
1 stop
$690JetBlue
Fri, Mar 27 - Fri, Apr 3
Delta Logo
10:00 am - 11:54 pm
RSW
-
STI
13h 54m
2 stops
Delta Logo
8:40 pm - 10:20 am
STI
-
RSW
13h 40m
1 stop
$763Delta
Fri, Mar 13 - Fri, Mar 20
JetBlue Logo
6:00 am - 8:40 pm
RSW
-
STI
13h 40m
1 stop
JetBlue Logo
11:06 pm - 1:09 pm
STI
-
RSW
15h 03m
1 stop
$841JetBlue
Mon, Feb 23 - Thu, Feb 26

United Airlines flights from Fort Myers to Santiago de los Caballeros

Our best United Airlines deals on Fort Myers to Santiago de los Caballeros flight tickets
United Airlines
Feb 23
RSW12:54 pmFort Myers SW Florida Intl
9h 57m
1 stop
STI11:51 pmSantiago de los Caballeros
Feb 26
STI6:00 amSantiago de los Caballeros
8h 57m
1 stop
RSW1:57 pmFort Myers SW Florida Intl
$1,073
United Airlines
Feb 23
RSW12:54 pmFort Myers SW Florida Intl
9h 57m
1 stop
STI11:51 pmSantiago de los Caballeros
Feb 26
STI6:00 amSantiago de los Caballeros
8h 57m
1 stop
RSW1:57 pmFort Myers SW Florida Intl
$1,128

JetBlue flights from Fort Myers to Santiago de los Caballeros

Our best JetBlue deals on Fort Myers to Santiago de los Caballeros flight tickets
JetBlue
Mar 13
RSW7:09 pmFort Myers SW Florida Intl
30h 38m
1 stop
STI1:47 amSantiago de los Caballeros
Mar 20
STI8:40 pmSantiago de los Caballeros
13h 04m
1 stop
RSW9:44 amFort Myers SW Florida Intl
$628
JetBlue
Jun 15
RSW8:07 pmFort Myers SW Florida Intl
21h 06m
1 stop
STI5:13 pmSantiago de los Caballeros
Jul 15
STI7:01 amSantiago de los Caballeros
15h 49m
1 stop
RSW10:50 pmFort Myers SW Florida Intl
$649
JetBlue
Mar 27
RSW3:10 pmFort Myers SW Florida Intl
12h 39m
1 stop
STI3:49 amSantiago de los Caballeros
Apr 3
STI8:30 amSantiago de los Caballeros
14h 50m
1 stop
RSW11:20 pmFort Myers SW Florida Intl
$690

momondo Fare Finder

 
Customize your flight search to find flights from Fort Myers to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 3/13

1:47 pm-1:49 am

2 stops12h 02m

Santiago de los Caballeros

Fri 3/20

3:43 pm-7:39 pm

3 stops27h 56m

$510

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 6/15

7:35 pm-9:13 pm

2 stops25h 38m

Santiago de los Caballeros

Wed 7/15

7:00 am-9:06 am

2 stops26h 06m

$521

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 3/13

8:34 pm-1:49 am

3 stops29h 15m

Santiago de los Caballeros

Fri 3/20

3:43 pm-3:05 pm

3 stops23h 22m

$528

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 3/13

1:47 pm-1:49 am

2 stops12h 02m

Santiago de los Caballeros

Thu 3/19

2:46 am-3:05 pm

2 stops12h 19m

$535

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 3/13

7:09 pm-1:47 am

1 stop30h 38m

Santiago de los Caballeros

Fri 3/20

8:40 pm-9:44 am

1 stop13h 04m

$628

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 6/15

6:50 am-12:30 am

2 stops17h 40m

Santiago de los Caballeros

Wed 7/15

8:50 pm-10:47 am

1 stop13h 57m

$633

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 6/15

8:07 pm-5:13 pm

1 stop21h 06m

Santiago de los Caballeros

Wed 7/15

7:01 am-10:50 pm

1 stop15h 49m

$649

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 3/27

3:10 pm-3:49 am

1 stop12h 39m

Santiago de los Caballeros

Fri 4/3

8:30 am-11:20 pm

1 stop14h 50m

$690

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 3/13

10:00 am-11:54 pm

2 stops13h 54m

Santiago de los Caballeros

Fri 3/20

8:40 pm-10:20 am

1 stop13h 40m

$763

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 2/23

6:00 am-8:40 pm

1 stop13h 40m

Santiago de los Caballeros

Thu 2/26

11:06 pm-1:09 pm

1 stop15h 03m

$841

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Fort Myers to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Fort Myers SW Florida Intl to Santiago de los Caballeros?

JetBlue and Spirit Airlines are the most popular carriers operating from Fort Myers SW Florida Intl to Santiago de los Caballeros

When to book flights from Fort Myers to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Fort Myers to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Fort Myers to Santiago de los Caballeros (RSW to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to Santiago de los Caballeros

Fastest flight time

9h 57m

Direct flights

None
The fastest flight from Fort Myers to Santiago de los Caballeros takes 9h 57m
There are no direct flights from Fort Myers to Santiago de los Caballeros. There are no popular flight routes from Fort Myers to Santiago de los Caballeros.
Search flight deals

  • How far is Fort Myers SW Florida Intl to Santiago de los Caballeros by plane?

    A flight from Fort Myers SW Florida Intl to Santiago de los Caballeros will travel around 865.6 mi. By plane, this route typically takes 9h 57m.

  • When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport?

    Prices for flights from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport were last updated today.

  • How old do you have to be to fly from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Fort Myers SW Florida Intl Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Fort Myers.

Can I find flights from Fort Myers to Santiago de los Caballeros with flexible booking policies on momondo?

Flights from Fort Myers to Santiago de los Caballeros with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Fort Myers to Santiago de los Caballeros?

Once all potential Fort Myers to Santiago de los Caballeros flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Fort Myers to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Fort Myers to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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