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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City from $260

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama City departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:50 am - 5:00 pm
DTW
-
PTY
35h 10m
3 stops
Multiple Airlines Logo
4:25 am - 7:52 am
PTY
-
DTW
26h 27m
3 stops
$559Multiple Airlines
Mon, Apr 27 - Tue, May 5
Multiple Airlines Logo
6:50 am - 8:37 pm
DTW
-
PTY
14h 47m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$562Multiple Airlines
Tue, Jun 2 - Tue, Jun 16
Multiple Airlines Logo
6:50 am - 8:37 pm
DTW
-
PTY
14h 47m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$574Multiple Airlines
Tue, Jun 2 - Wed, Jun 17
Multiple Airlines Logo
12:55 pm - 8:06 am
DTW
-
PTY
20h 11m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$575Multiple Airlines
Mon, Jun 1 - Tue, Jun 16
Multiple Airlines Logo
2:40 pm - 7:20 pm
DTW
-
PTY
29h 40m
2 stops
Multiple Airlines Logo
6:34 pm - 11:59 pm
PTY
-
DTW
28h 25m
1 stop
$576Multiple Airlines
Sat, May 30 - Tue, Jun 16
Multiple Airlines Logo
8:25 am - 12:35 am
DTW
-
PTY
41h 10m
3 stops
Multiple Airlines Logo
5:30 am - 10:52 pm
PTY
-
DTW
16h 22m
3 stops
$581Multiple Airlines
Mon, Apr 27 - Sat, May 2
Multiple Airlines Logo
12:55 pm - 8:06 am
DTW
-
PTY
20h 11m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$587Multiple Airlines
Mon, Jun 1 - Wed, Jun 17
Multiple Airlines Logo
6:20 am - 7:20 pm
DTW
-
PTY
14h 00m
2 stops
Multiple Airlines Logo
12:23 pm - 11:59 pm
PTY
-
DTW
10h 36m
1 stop
$588Multiple Airlines
Wed, Jun 3 - Wed, Jun 17
Multiple Airlines Logo
6:50 am - 12:35 am
DTW
-
PTY
42h 45m
3 stops
Multiple Airlines Logo
3:10 pm - 11:53 pm
PTY
-
DTW
31h 43m
2 stops
$591Multiple Airlines
Mon, Apr 27 - Tue, May 5
Multiple Airlines Logo
8:25 am - 9:15 am
DTW
-
PTY
25h 50m
3 stops
Multiple Airlines Logo
3:10 pm - 11:59 pm
PTY
-
DTW
31h 49m
2 stops
$599Multiple Airlines
Mon, Apr 27 - Sat, May 2

Copa Airlines flights from Detroit Metropolitan Wayne County Airport to Panama City

Our best Copa Airlines deals on Detroit Metropolitan Wayne County Airport to Panama City flight tickets
Copa Airlines
Apr 16
DTW9:00 amDetroit Metropolitan Wayne County
10h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 29
PTY10:55 pmPanama City Tocumen Intl
15h 53m
1 stop
DTW3:48 pmDetroit Metropolitan Wayne County
$911
Copa Airlines
Apr 20
DTW10:55 amDetroit Metropolitan Wayne County
8h 42m
1 stop
PTY6:37 pmPanama City Tocumen Intl
May 4
PTY3:30 pmPanama City Tocumen Intl
19h 24m
1 stop
DTW11:54 amDetroit Metropolitan Wayne County
$917

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

6:50 am-5:00 pm

3 stops35h 10m

Panama City Tocumen Intl

Tue 5/5

4:25 am-7:52 am

3 stops26h 27m

$559

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/2

6:50 am-8:37 pm

2 stops14h 47m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$562

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/2

6:50 am-8:37 pm

2 stops14h 47m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$574

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 6/1

12:55 pm-8:06 am

2 stops20h 11m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$575

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 5/30

2:40 pm-7:20 pm

2 stops29h 40m

Panama City Tocumen Intl

Tue 6/16

6:34 pm-11:59 pm

1 stop28h 25m

$576

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

8:25 am-12:35 am

3 stops41h 10m

Panama City Tocumen Intl

Sat 5/2

5:30 am-10:52 pm

3 stops16h 22m

$581

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 6/1

12:55 pm-8:06 am

2 stops20h 11m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$587
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 6/3

6:20 am-7:20 pm

2 stops14h 00m

Panama City Tocumen Intl

Wed 6/17

12:23 pm-11:59 pm

1 stop10h 36m

$588

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

6:50 am-12:35 am

3 stops42h 45m

Panama City Tocumen Intl

Tue 5/5

3:10 pm-11:53 pm

2 stops31h 43m

$591

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 4/27

8:25 am-9:15 am

3 stops25h 50m

Panama City Tocumen Intl

Sat 5/2

3:10 pm-11:59 pm

2 stops31h 49m

$599

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and Panama City?

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $704. If you’re not able to fly to Panama City in October, then August is your next best option. Flight prices from Detroit Metropolitan Wayne County Airport to Panama City during August average around $754.

When to book flights from Detroit Metropolitan Wayne County Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Panama City (DTW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama City

Fastest flight time

8h 45m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama City takes 8h 45m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama City. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Panama City.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Panama City

  • How far is Detroit Metropolitan Wayne County to Panama City Tocumen Intl by plane?

    A flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl will travel around 2306.7 mi. In terms of flight time, this usually takes a little over 8h 45m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Panama City?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama City

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $514Free CancellationRating
7.5
1,572 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $628Free CancellationRating
7.1
11,570 reviews
Search American Airlines flights
United AirlinesPriceFrom $629Free CancellationRating
7.4
9,574 reviews
Search United Airlines flights
DeltaPriceFrom $668Free CancellationRating
7.9
8,408 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Detroit to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Flights from Detroit to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Detroit.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.

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