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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City from $304

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama City departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$609Multiple Airlines
Wed, Sep 30 - Sun, Oct 4
Multiple Airlines Logo
6:00 am - 10:30 am
DTW
-
PTY
29h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$617Multiple Airlines
Tue, Sep 15 - Tue, Sep 29
Multiple Airlines Logo
5:30 pm - 2:55 pm
DTW
-
PTY
22h 25m
3 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$634Multiple Airlines
Fri, Sep 25 - Sun, Sep 27
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
11:25 am - 4:32 pm
PTY
-
DTW
28h 07m
3 stops
$642Multiple Airlines
Wed, Sep 16 - Wed, Sep 30
Multiple Airlines Logo
5:30 pm - 2:55 pm
DTW
-
PTY
22h 25m
3 stops
Multiple Airlines Logo
11:25 am - 4:32 pm
PTY
-
DTW
28h 07m
3 stops
$649Multiple Airlines
Fri, Sep 25 - Sun, Sep 27
Multiple Airlines Logo
6:00 am - 10:30 am
DTW
-
PTY
29h 30m
2 stops
Multiple Airlines Logo
11:25 am - 4:32 pm
PTY
-
DTW
28h 07m
3 stops
$650Multiple Airlines
Thu, Oct 1 - Sun, Oct 4
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$665Multiple Airlines
Wed, Sep 16 - Wed, Sep 23
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$666Multiple Airlines
Fri, Oct 9 - Sun, Oct 18
Multiple Airlines Logo
6:00 am - 10:30 am
DTW
-
PTY
29h 30m
2 stops
Multiple Airlines Logo
3:50 pm - 4:32 pm
PTY
-
DTW
23h 42m
2 stops
$669Multiple Airlines
Fri, Oct 9 - Sun, Oct 18
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
Multiple Airlines Logo
3:50 pm - 11:55 pm
PTY
-
DTW
31h 05m
2 stops
$673Multiple Airlines
Mon, Oct 12 - Sat, Oct 17

United Airlines flights from Detroit Metropolitan Wayne County Airport to Panama City

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Panama City flight tickets
United Airlines
Sep 15
DTW7:00 amDetroit Metropolitan Wayne County
13h 31m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Sep 29
PTY3:30 pmPanama City Tocumen Intl
17h 04m
2 stops
DTW9:34 amDetroit Metropolitan Wayne County
$737
United Airlines
Nov 10
DTW8:50 amDetroit Metropolitan Wayne County
10h 48m
2 stops
PTY7:38 pmPanama City Tocumen Intl
Nov 19
PTY10:00 amPanama City Tocumen Intl
13h 52m
2 stops
DTW11:52 pmDetroit Metropolitan Wayne County
$757
United Airlines
Nov 5
DTW8:15 amDetroit Metropolitan Wayne County
11h 23m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Nov 13
PTY10:00 amPanama City Tocumen Intl
13h 04m
1 stop
DTW11:04 pmDetroit Metropolitan Wayne County
$780

Avianca flights from Detroit Metropolitan Wayne County Airport to Panama City

Our best Avianca deals on Detroit Metropolitan Wayne County Airport to Panama City flight tickets
Avianca
Jun 2
DTW7:45 pmDetroit Metropolitan Wayne County
15h 45m
2 stops
PTY10:30 amPanama City Tocumen Intl
Jun 3
PTY3:50 pmPanama City Tocumen Intl
17h 24m
2 stops
DTW10:14 amDetroit Metropolitan Wayne County
$1,020
Avianca
Jun 1
DTW10:15 amDetroit Metropolitan Wayne County
16h 40m
2 stops
PTY1:55 amPanama City Tocumen Intl
Jun 6
PTY5:30 amPanama City Tocumen Intl
12h 32m
2 stops
DTW7:02 pmDetroit Metropolitan Wayne County
$1,104
Avianca
Jun 1
DTW10:13 amDetroit Metropolitan Wayne County
25h 17m
2 stops
PTY10:30 amPanama City Tocumen Intl
Jun 6
PTY5:30 amPanama City Tocumen Intl
27h 44m
2 stops
DTW10:14 amDetroit Metropolitan Wayne County
$1,143

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 30, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/30

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Sun 10/4

3:50 pm-4:32 pm

2 stops23h 42m

$609

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/15

6:00 am-10:30 am

2 stops29h 30m

Panama City Tocumen Intl

Tue 9/29

3:50 pm-4:32 pm

2 stops23h 42m

$617

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 9/25

5:30 pm-2:55 pm

3 stops22h 25m

Panama City Tocumen Intl

Sun 9/27

3:50 pm-4:32 pm

2 stops23h 42m

$634

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Wed 9/30

11:25 am-4:32 pm

3 stops28h 07m

$642

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 9/25

5:30 pm-2:55 pm

3 stops22h 25m

Panama City Tocumen Intl

Sun 9/27

11:25 am-4:32 pm

3 stops28h 07m

$649

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 10/1

6:00 am-10:30 am

2 stops29h 30m

Panama City Tocumen Intl

Sun 10/4

11:25 am-4:32 pm

3 stops28h 07m

$650

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Wed 9/23

3:50 pm-4:32 pm

2 stops23h 42m

$665

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 10/9

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Sun 10/18

3:50 pm-4:32 pm

2 stops23h 42m

$666

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 10/9

6:00 am-10:30 am

2 stops29h 30m

Panama City Tocumen Intl

Sun 10/18

3:50 pm-4:32 pm

2 stops23h 42m

$669

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 10/12

5:30 pm-10:30 am

2 stops18h 00m

Panama City Tocumen Intl

Sat 10/17

3:50 pm-11:55 pm

2 stops31h 05m

$673

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and Panama City?

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $756. If you’re not able to fly to Panama City in October, then January is your next best option. Flight prices from Detroit Metropolitan Wayne County Airport to Panama City during January average around $763.

When to book flights from Detroit Metropolitan Wayne County Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Panama City (DTW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama City

Fastest flight time

8h 59m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama City takes 8h 59m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama City. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Panama City.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Panama City

  • How far is Detroit Metropolitan Wayne County to Panama City Tocumen Intl by plane?

    A flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl will travel around 2306.7 mi. In terms of flight time, this usually takes a little over 8h 59m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Panama City?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama City

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $611Free CancellationRating
7.5
1,574 reviews
Search Copa Airlines flights
DeltaPriceFrom $668Free CancellationRating
7.9
8,417 reviews
Search Delta flights
American AirlinesPriceFrom $673Free CancellationRating
7.1
11,640 reviews
Search American Airlines flights
United AirlinesPriceFrom $708Free CancellationRating
7.4
9,766 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Detroit to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Flights from Detroit to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Detroit.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.

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