Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City from $210

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama City departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:24 am - 10:30 am
DTW
-
PTY
25h 06m
3 stops
Multiple Airlines Logo
3:05 am - 6:44 pm
PTY
-
DTW
14h 39m
2 stops
$476Multiple Airlines
Thu, Apr 9 - Wed, Apr 15
Multiple Airlines Logo
4:50 pm - 2:00 pm
DTW
-
PTY
22h 10m
2 stops
Multiple Airlines Logo
2:55 am - 12:20 pm
PTY
-
DTW
32h 25m
2 stops
$482Multiple Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
6:05 am - 2:00 pm
DTW
-
PTY
32h 55m
3 stops
Multiple Airlines Logo
9:45 am - 12:20 pm
PTY
-
DTW
25h 35m
2 stops
$484Multiple Airlines
Tue, Mar 17 - Wed, Mar 25
Multiple Airlines Logo
2:15 pm - 2:00 pm
DTW
-
PTY
24h 45m
2 stops
Multiple Airlines Logo
3:25 am - 10:37 pm
PTY
-
DTW
18h 12m
3 stops
$487Multiple Airlines
Mon, Mar 9 - Tue, Apr 7
Multiple Airlines Logo
7:15 am - 8:19 pm
DTW
-
PTY
14h 04m
1 stop
Multiple Airlines Logo
12:03 pm - 12:46 am
PTY
-
DTW
11h 43m
1 stop
$493Multiple Airlines
Thu, Apr 9 - Thu, Apr 16
Multiple Airlines Logo
11:34 am - 8:50 am
DTW
-
PTY
22h 16m
3 stops
Multiple Airlines Logo
2:55 pm - 12:20 pm
PTY
-
DTW
20h 25m
2 stops
$494Multiple Airlines
Mon, Mar 16 - Wed, Mar 18
Multiple Airlines Logo
5:45 am - 12:40 am
DTW
-
PTY
19h 55m
2 stops
Multiple Airlines Logo
5:55 pm - 12:20 pm
PTY
-
DTW
17h 25m
2 stops
$497Multiple Airlines
Mon, Mar 9 - Wed, Apr 8
Multiple Airlines Logo
2:15 pm - 2:00 pm
DTW
-
PTY
24h 45m
2 stops
Multiple Airlines Logo
3:25 am - 10:37 pm
PTY
-
DTW
18h 12m
3 stops
$502Multiple Airlines
Mon, Mar 9 - Tue, Apr 7
Multiple Airlines Logo
11:34 am - 8:50 am
DTW
-
PTY
22h 16m
3 stops
Multiple Airlines Logo
5:50 pm - 10:37 pm
PTY
-
DTW
27h 47m
3 stops
$505Multiple Airlines
Mon, Mar 16 - Wed, Mar 18
Multiple Airlines Logo
5:20 am - 1:05 am
DTW
-
PTY
20h 45m
2 stops
Multiple Airlines Logo
3:05 am - 11:59 pm
PTY
-
DTW
19h 54m
2 stops
$506Multiple Airlines
Tue, Apr 7 - Mon, Apr 13

Copa Airlines flights from Detroit Metropolitan Wayne County Airport to Panama City

Our best Copa Airlines deals on Detroit Metropolitan Wayne County Airport to Panama City flight tickets
Copa Airlines
Mar 2
DTW11:00 amDetroit Metropolitan Wayne County
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Apr 30
PTY7:55 amPanama City Tocumen Intl
14h 52m
1 stop
DTW11:47 pmDetroit Metropolitan Wayne County
$816
Copa Airlines
Mar 11
DTW5:48 amDetroit Metropolitan Wayne County
9h 12m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Mar 21
PTY9:11 amPanama City Tocumen Intl
8h 44m
1 stop
DTW6:55 pmDetroit Metropolitan Wayne County
$861
Copa Airlines
Mar 3
DTW10:28 amDetroit Metropolitan Wayne County
10h 07m
1 stop
PTY8:35 pmPanama City Tocumen Intl
Apr 4
PTY9:13 amPanama City Tocumen Intl
8h 38m
1 stop
DTW6:51 pmDetroit Metropolitan Wayne County
$975

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 25, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 4/9

10:24 am-10:30 am

3 stops25h 06m

Panama City Tocumen Intl

Wed 4/15

3:05 am-6:44 pm

2 stops14h 39m

$476

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 3/17

4:50 pm-2:00 pm

2 stops22h 10m

Panama City Tocumen Intl

Tue 3/24

2:55 am-12:20 pm

2 stops32h 25m

$482

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 3/17

6:05 am-2:00 pm

3 stops32h 55m

Panama City Tocumen Intl

Wed 3/25

9:45 am-12:20 pm

2 stops25h 35m

$484

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/9

2:15 pm-2:00 pm

2 stops24h 45m

Panama City Tocumen Intl

Tue 4/7

3:25 am-10:37 pm

3 stops18h 12m

$487

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 4/9

7:15 am-8:19 pm

1 stop14h 04m

Panama City Tocumen Intl

Thu 4/16

12:03 pm-12:46 am

1 stop11h 43m

$493

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/16

11:34 am-8:50 am

3 stops22h 16m

Panama City Tocumen Intl

Wed 3/18

2:55 pm-12:20 pm

2 stops20h 25m

$494

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/9

5:45 am-12:40 am

2 stops19h 55m

Panama City Tocumen Intl

Wed 4/8

5:55 pm-12:20 pm

2 stops17h 25m

$497

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/9

2:15 pm-2:00 pm

2 stops24h 45m

Panama City Tocumen Intl

Tue 4/7

3:25 am-10:37 pm

3 stops18h 12m

$502

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 3/16

11:34 am-8:50 am

3 stops22h 16m

Panama City Tocumen Intl

Wed 3/18

5:50 pm-10:37 pm

3 stops27h 47m

$505

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 4/7

5:20 am-1:05 am

2 stops20h 45m

Panama City Tocumen Intl

Mon 4/13

3:05 am-11:59 pm

2 stops19h 54m

$506

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, June is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $722. If you’re not able to fly to Panama City in June, then October is your next best option. Flight prices from Detroit Metropolitan Wayne County Airport to Panama City during October average around $736.

When to book flights from Detroit Metropolitan Wayne County Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Panama City (DTW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama City

Fastest flight time

8h 31m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama City takes 8h 31m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama City. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Panama City.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Panama City Tocumen Intl by plane?

    A flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl will travel around 2306.7 mi. In terms of flight time, this usually takes a little over 8h 31m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Panama City?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama City

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $578Free CancellationRating
7.1
11,347 reviews
Search American Airlines flights
DeltaPriceFrom $608Free CancellationRating
7.9
8,238 reviews
Search Delta flights
Copa AirlinesPriceFrom $623Free CancellationRating
7.5
1,557 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $629Free CancellationRating
7.4
9,343 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Detroit to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Flights from Detroit to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Detroit.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 3/27
Fri 4/3
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama