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Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City from $290

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Panama City departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:00 am - 8:19 pm
DTW
-
PTY
9h 19m
1 stop
Multiple Airlines Logo
12:21 pm - 1:07 pm
PTY
-
DTW
24h 46m
2 stops
$580Multiple Airlines
Wed, Nov 11 - Mon, Nov 16
Multiple Airlines Logo
3:25 pm - 8:31 pm
DTW
-
PTY
30h 06m
1 stop
Multiple Airlines Logo
12:21 pm - 11:27 pm
PTY
-
DTW
34h 06m
2 stops
$601Multiple Airlines
Fri, Sep 18 - Tue, Sep 22
American Airlines Logo
5:30 am - 3:38 pm
DTW
-
PTY
10h 08m
1 stop
American Airlines Logo
2:39 pm - 11:53 pm
PTY
-
DTW
9h 14m
1 stop
$733American Airlines
Fri, Jan 22 - Wed, Mar 3
Delta Logo
6:25 am - 2:05 pm
DTW
-
PTY
7h 40m
1 stop
Delta Logo
3:30 pm - 12:59 am
PTY
-
DTW
9h 29m
1 stop
$733Delta
Thu, Nov 26 - Tue, Dec 8
Delta Logo
5:20 am - 2:05 pm
DTW
-
PTY
8h 45m
1 stop
Delta Logo
3:30 pm - 12:59 am
PTY
-
DTW
9h 29m
1 stop
$733Delta
Wed, Nov 25 - Wed, Dec 9
United Airlines Logo
11:34 am - 8:02 pm
DTW
-
PTY
8h 28m
1 stop
United Airlines Logo
10:00 am - 9:08 pm
PTY
-
DTW
11h 08m
1 stop
$733United Airlines
Tue, Nov 24 - Wed, Dec 9
United Airlines Logo
8:30 am - 8:02 pm
DTW
-
PTY
11h 32m
1 stop
United Airlines Logo
10:00 am - 11:04 pm
PTY
-
DTW
13h 04m
1 stop
$733United Airlines
Tue, Nov 24 - Mon, Dec 7
American Airlines Logo
5:21 pm - 1:48 pm
DTW
-
PTY
20h 27m
2 stops
American Airlines Logo
2:50 pm - 9:48 am
PTY
-
DTW
18h 58m
2 stops
$737American Airlines
Thu, Dec 3 - Fri, Dec 11
Copa Airlines Logo
5:25 am - 8:41 pm
DTW
-
PTY
16h 16m
1 stop
Copa Airlines Logo
6:41 pm - 10:10 am
PTY
-
DTW
14h 29m
1 stop
$887Copa Airlines
Mon, Sep 14 - Mon, Sep 21
Copa Airlines Logo
10:55 am - 6:37 pm
DTW
-
PTY
8h 42m
1 stop
Copa Airlines Logo
9:45 am - 11:36 pm
PTY
-
DTW
12h 51m
1 stop
$1,043Copa Airlines
Tue, Aug 11 - Tue, Aug 18

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United Airlines flights from Detroit Metropolitan Wayne County Airport to Panama City

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Panama City flight tickets
United Airlines
Nov 24
DTW11:34 amDetroit Metropolitan Wayne County
8h 28m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Dec 8
PTY10:00 amPanama City Tocumen Intl
13h 04m
1 stop
DTW11:04 pmDetroit Metropolitan Wayne County
$733
United Airlines
Nov 24
DTW11:34 amDetroit Metropolitan Wayne County
8h 28m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Dec 6
PTY10:00 amPanama City Tocumen Intl
9h 38m
1 stop
DTW7:38 pmDetroit Metropolitan Wayne County
$758
United Airlines
Jan 10
DTW2:15 pmDetroit Metropolitan Wayne County
24h 30m
2 stops
PTY2:45 pmPanama City Tocumen Intl
Jan 24
PTY8:55 amPanama City Tocumen Intl
14h 49m
1 stop
DTW11:44 pmDetroit Metropolitan Wayne County
$762

Delta flights from Detroit Metropolitan Wayne County Airport to Panama City

Our best Delta deals on Detroit Metropolitan Wayne County Airport to Panama City flight tickets
Delta
Nov 27
DTW6:25 amDetroit Metropolitan Wayne County
7h 40m
1 stop
PTY2:05 pmPanama City Tocumen Intl
Dec 8
PTY3:30 pmPanama City Tocumen Intl
8h 29m
1 stop
DTW11:59 pmDetroit Metropolitan Wayne County
$760
Delta
Aug 6
DTW6:20 amDetroit Metropolitan Wayne County
7h 35m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Aug 11
PTY2:20 pmPanama City Tocumen Intl
9h 39m
1 stop
DTW12:59 amDetroit Metropolitan Wayne County
$1,284

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 11/11

11:00 am-8:19 pm

1 stop9h 19m

Panama City Tocumen Intl

Mon 11/16

12:21 pm-1:07 pm

2 stops24h 46m

$580

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 9/18

3:25 pm-8:31 pm

1 stop30h 06m

Panama City Tocumen Intl

Tue 9/22

12:21 pm-11:27 pm

2 stops34h 06m

$601

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 1/22

5:30 am-3:38 pm

1 stop10h 08m

Panama City Tocumen Intl

Wed 3/3

2:39 pm-11:53 pm

1 stop9h 14m

$733
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 11/26

6:25 am-2:05 pm

1 stop7h 40m

Panama City Tocumen Intl

Tue 12/8

3:30 pm-12:59 am

1 stop9h 29m

$733

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 11/25

5:20 am-2:05 pm

1 stop8h 45m

Panama City Tocumen Intl

Wed 12/9

3:30 pm-12:59 am

1 stop9h 29m

$733

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 11/24

11:34 am-8:02 pm

1 stop8h 28m

Panama City Tocumen Intl

Wed 12/9

10:00 am-9:08 pm

1 stop11h 08m

$733

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 11/24

8:30 am-8:02 pm

1 stop11h 32m

Panama City Tocumen Intl

Mon 12/7

10:00 am-11:04 pm

1 stop13h 04m

$733

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 12/3

5:21 pm-1:48 pm

2 stops20h 27m

Panama City Tocumen Intl

Fri 12/11

2:50 pm-9:48 am

2 stops18h 58m

$737

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 9/14

5:25 am-8:41 pm

1 stop16h 16m

Panama City Tocumen Intl

Mon 9/21

6:41 pm-10:10 am

1 stop14h 29m

$887

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 8/11

10:55 am-6:37 pm

1 stop8h 42m

Panama City Tocumen Intl

Tue 8/18

9:45 am-11:36 pm

1 stop12h 51m

$1,043

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Detroit Metropolitan Wayne County Airport and Panama City?

Prices are currently low for flights on this route.

Typical prices usually range from $709 to $1,156.
The lowest price recently found on this route was $580.

What is the cheapest month to fly to Panama City?

In general, January is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $753. If you’re not able to fly to Panama City in January, then September is your next best option. Flight prices from Detroit Metropolitan Wayne County Airport to Panama City during September average around $768.

When to book flights from Detroit Metropolitan Wayne County Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Panama City (DTW to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Panama City

Fastest flight time

8h 57m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Panama City takes 8h 57m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Panama City. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Panama City.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Panama City

  • How far is Detroit Metropolitan Wayne County to Panama City Tocumen Intl by plane?

    A flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl will travel around 2306.7 mi. In terms of flight time, this usually takes a little over 8h 57m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Panama City?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Panama City

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $611Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
DeltaPriceFrom $655Free CancellationRating
7.8
8,497 reviews
Search Delta flights
American AirlinesPriceFrom $663Free CancellationRating
7.1
11,846 reviews
Search American Airlines flights
United AirlinesPriceFrom $708Free CancellationRating
7.4
10,062 reviews
Search United Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Detroit to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Detroit to Panama City with flexible booking policies on momondo?

Flights from Detroit to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from Detroit.

I’m not ready to book a flight from Detroit to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Detroit and alert you when they change.

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