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Cheap flights from Detroit Metropolitan Wayne County Airport to Brussels from $306

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Brussels departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
British Airways Logo
1:12 pm - 2:05 pm
DTW
-
BRU
18h 53m2 stops
British Airways Logo
10:55 am - 10:45 pm
BRU
-
DTW
17h 50m2 stops
$554British Airways
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
5:00 am - 9:35 am
DTW
-
BRU
22h 35m2 stops
Multiple Airlines Logo
10:15 am - 12:19 am
BRU
-
DTW
20h 04m2 stops
$564Multiple Airlines
Wed, Feb 4 - Wed, Feb 11
Turkish Airlines Logo
8:05 pm - 5:05 pm
DTW
-
BRU
15h 00m1 stop
Turkish Airlines Logo
11:35 am - 6:10 pm
BRU
-
DTW
36h 35m1 stop
$578Turkish Airlines
Thu, Feb 5 - Thu, Feb 12
British Airways Logo
4:07 pm - 2:05 pm
DTW
-
BRU
15h 58m2 stops
British Airways Logo
3:15 pm - 10:45 pm
BRU
-
DTW
37h 30m2 stops
$588British Airways
Wed, Apr 15 - Wed, Apr 22
KLM Logo
4:05 pm - 7:35 am
DTW
-
BRU
9h 30m1 stop
KLM Logo
6:20 am - 1:35 pm
BRU
-
DTW
13h 15m1 stop
$590KLM
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
5:30 am - 9:35 am
DTW
-
BRU
22h 05m3 stops
Multiple Airlines Logo
10:15 am - 12:19 am
BRU
-
DTW
20h 04m2 stops
$592Multiple Airlines
Wed, Feb 4 - Wed, Feb 11
Delta Logo
2:55 pm - 9:40 am
DTW
-
BRU
12h 45m2 stops
Delta Logo
6:20 am - 1:35 pm
BRU
-
DTW
13h 15m1 stop
$594Delta
Wed, Apr 15 - Wed, Apr 22
Delta Logo
10:00 am - 7:35 am
DTW
-
BRU
15h 35m2 stops
Delta Logo
6:20 am - 11:54 am
BRU
-
DTW
11h 34m1 stop
$595Delta
Wed, Apr 15 - Wed, Apr 22
Turkish Airlines Logo
8:50 pm - 1:25 pm
DTW
-
BRU
34h 35m1 stop
Turkish Airlines Logo
11:10 am - 6:45 pm
BRU
-
DTW
37h 35m1 stop
$596Turkish Airlines
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
5:00 am - 6:40 pm
DTW
-
BRU
31h 40m2 stops
Multiple Airlines Logo
7:20 pm - 12:25 am
BRU
-
DTW
35h 05m2 stops
$600Multiple Airlines
Thu, Feb 5 - Thu, Feb 12

American Airlines flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport flight tickets
American Airlines
Mar 3
DTW5:24 pmDetroit Metropolitan Wayne County
17h 36m
2 stops
BRU5:00 pmBrussels Bruxelles-National
Mar 8
BRU11:20 amBrussels Bruxelles-National
17h 13m
3 stops
DTW11:33 pmDetroit Metropolitan Wayne County
$780
Find similar
American Airlines
Feb 28
DTW4:30 pmDetroit Metropolitan Wayne County
17h 00m
2 stops
BRU3:30 pmBrussels Bruxelles-National
Mar 8
BRU11:20 amBrussels Bruxelles-National
17h 13m
3 stops
DTW11:33 pmDetroit Metropolitan Wayne County
$785
Find similar
American Airlines
Feb 27
DTW5:13 pmDetroit Metropolitan Wayne County
14h 27m
2 stops
BRU1:40 pmBrussels Bruxelles-National
Mar 2
BRU11:50 amBrussels Bruxelles-National
18h 53m
3 stops
DTW12:43 amDetroit Metropolitan Wayne County
$830
Find similar

Turkish Airlines flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport

Our best Turkish Airlines deals on Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport flight tickets
Turkish Airlines
Feb 5
DTW8:05 pmDetroit Metropolitan Wayne County
15h 00m
1 stop
BRU5:05 pmBrussels Bruxelles-National
Feb 12
BRU11:35 amBrussels Bruxelles-National
36h 35m
1 stop
DTW6:10 pmDetroit Metropolitan Wayne County
$578
Find similar
Turkish Airlines
Apr 15
DTW8:50 pmDetroit Metropolitan Wayne County
34h 35m
1 stop
BRU1:25 pmBrussels Bruxelles-National
Apr 22
BRU11:10 amBrussels Bruxelles-National
37h 35m
1 stop
DTW6:45 pmDetroit Metropolitan Wayne County
$596
Find similar
Turkish Airlines
Feb 4
DTW8:05 pmDetroit Metropolitan Wayne County
20h 05m
1 stop
BRU10:10 pmBrussels Bruxelles-National
Feb 11
BRU11:35 amBrussels Bruxelles-National
36h 35m
1 stop
DTW6:10 pmDetroit Metropolitan Wayne County
$601
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Wed 4/15

1:12 pm-2:05 pm

2 stops18h 53m

Brussels Bruxelles-National

Wed 4/22

10:55 am-10:45 pm

2 stops17h 50m

$554

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Wed 2/4

5:00 am-9:35 am

2 stops22h 35m

Brussels Bruxelles-National

Wed 2/11

10:15 am-12:19 am

2 stops20h 04m

$564

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Thu 2/5

8:05 pm-5:05 pm

1 stop15h 00m

Brussels Bruxelles-National

Thu 2/12

11:35 am-6:10 pm

1 stop36h 35m

$578

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Wed 4/15

4:07 pm-2:05 pm

2 stops15h 58m

Brussels Bruxelles-National

Wed 4/22

3:15 pm-10:45 pm

2 stops37h 30m

$588

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Wed 4/15

4:05 pm-7:35 am

1 stop9h 30m

Brussels Bruxelles-National

Wed 4/22

6:20 am-1:35 pm

1 stop13h 15m

$590

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Wed 2/4

5:30 am-9:35 am

3 stops22h 05m

Brussels Bruxelles-National

Wed 2/11

10:15 am-12:19 am

2 stops20h 04m

$592

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Wed 4/15

2:55 pm-9:40 am

2 stops12h 45m

Brussels Bruxelles-National

Wed 4/22

6:20 am-1:35 pm

1 stop13h 15m

$594

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Wed 4/15

10:00 am-7:35 am

2 stops15h 35m

Brussels Bruxelles-National

Wed 4/22

6:20 am-11:54 am

1 stop11h 34m

$595

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Wed 4/15

8:50 pm-1:25 pm

1 stop34h 35m

Brussels Bruxelles-National

Wed 4/22

11:10 am-6:45 pm

1 stop37h 35m

$596

DetroitBrussels

DTW - BRU

DTWBRU

Detroit Metropolitan Wayne County

Thu 2/5

5:00 am-6:40 pm

2 stops31h 40m

Brussels Bruxelles-National

Thu 2/12

7:20 pm-12:25 am

2 stops35h 05m

$600

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Brussels Bruxelles-National Airport?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport is on a Saturday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Saturday will often find tickets for as low as $863. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport for around $1,122.

What is the cheapest time of day to depart on your flight to Brussels Bruxelles-National Airport?

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is in the morning. Flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport during this time can be as low as $795. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $995 on average. Flights to Brussels Bruxelles-National Airport from Detroit Metropolitan Wayne County Airport in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport (DTW to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport

Fastest flight time

9h 45m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport takes 9h 45m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Brussels Bruxelles-National by plane?

    Detroit Metropolitan Wayne County and Brussels Bruxelles-National are 3961.4 mi apart from one another. Typically, this will take 9h 45m by plane in normal conditions.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport refresh daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The travel and health documents required for your trip to Brussels Bruxelles-National Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Brussels Bruxelles-National Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
IcelandairPriceFrom $441Free CancellationRating
7.0
592 reviews
Search Icelandair flights
Turkish AirlinesPriceFrom $530Free CancellationRating
7.3
4,112 reviews
Search Turkish Airlines flights
KLMPriceFrom $558Free CancellationRating
7.7
1,434 reviews
Search KLM flights
United AirlinesPriceFrom $590Free CancellationRating
7.4
9,106 reviews
Search United Airlines flights
DeltaPriceFrom $689Free CancellationRating
7.9
8,013 reviews
Search Delta flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Bruges
Ghent
Leuven
Charleroi
Hasselt
Spa
Zaventem
Namur
Dinant
Genk
Mons
Durbuy
Waterloo
Aalst
Mechelen
Francorchamps
Knokke-Heist
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Brussels?

Finding the right flight to Brussels from Detroit is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Brussels quick and easy, saving you time and money.

Can I find flights from Detroit to Brussels with flexible booking policies on momondo?

Yes. All flights to Brussels from Detroit on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Detroit to Brussels?

Once all potential Detroit to Brussels flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Brussels right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Brussels now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Brussels and let you know when they change.

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