Cheap flights from Caribbean Islands to Panama City from $201

In general, September is the cheapest month to fly from Caribbean Islands to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $414. If you’re not able to fly to Panama City in September, then August is your next best option. Flight prices from Caribbean Islands to Panama City during August average around $415.

Our data shows that Wednesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $413. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $438. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Caribbean Islands to Panama City during this time can be as low as $403. Try not to purchase tickets in the morning because they tend to be around $432. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from San Juan Luis Munoz Marin Intl to Panama City Tocumen Intl for the best Caribbean Islands - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Caribbean Islands when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $442 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Caribbean Islands for as low as $395 on momondo.

There are 3 cabin classes available to choose from on Caribbean Islands to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Avianca, WestJet, and Cayman Airways are the most popular carriers operating from Caribbean Islands to Panama City Tocumen Intl

Copa Airlines, Avianca and American Airlines are the top three most popular airlines that fly to Panama City from Caribbean Islands according to our data. Copa Airlines is the first choice among our users, with 89% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

The number of flights available between Caribbean Islands and Panama City is 37 per day as of April 2026. The most frequent departure time is 12:00PM, with 66% of daily flights leaving in the afternoon.

As of April 2026, 259 flights take off from Caribbean Islands and land in Panama City each week. The most common flight departure day for this route is Wed, with 19% of weekly flights taking off on this day.