Our hotel, in Piedmont, is home away from home for Clemson Tigers fans, and we take southern hospitality seriously here. With friendly service and excellent TripAdvisor® ratings, guests know they're in for a real treat when choosing our Piedmont hotel. We are the perfect location if you need convenient access to I-85, youth and adult sporting events, and shopping. Our top-notch amenities and luxury bedding will make your good trip a great one. At our Piedmont hotel, we always go above and beyond to ensure your comfort. Hotels in Piedmont may be known for their customer service, but what about a great value and location? Local small businesses send their employees to our Piedmont hotel because we deliver the best in service time and time again. Other nearby hotels just can't compete with our amenities. An unbeatable value and convenient location make staying with us your best choice. Workers with Palmetto Health, CLC Lodging, South Carolina Technology & Aviation Center, and Peterbilt are just a few of the business travelers who prefer our property when traveling for work. Even though Clemson Tigers football games bring fans together from around the region, there's also plenty of outdoor recreational fun to be had close by. Hiking, biking, fishing, and swimming at Lake Hartwell is a summertime favorite for everyone. Enjoy a delicious meal at our nearby restaurants, Cracker Barrell®, Catrina’s, and more! Take advantage of our spacious, cool rooms, and the friendliest service in town. If you need tips, recommendations, or advice on the best places to eat, shop, or play, our staff members are happy to help. When it comes to hospitality, you only deserve the best and that's what we guarantee. Reserve your room at the Best Western Plus Greenville South and you'll be glad you did!