Cheap flights from Syracuse to Panama City from $226

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to Panama City departing on 1/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Delta Logo
6:00 am - 1:55 pm
SYR
-
PTY
7h 55m1 stop
Delta Logo
3:20 pm - 11:51 pm
PTY
-
SYR
8h 31m1 stop
$518Delta
Wed, Jan 28 - Wed, Feb 4
United Airlines Logo
4:57 pm - 5:07 pm
SYR
-
PTY
24h 10m2 stops
United Airlines Logo
4:41 pm - 4:15 pm
PTY
-
SYR
23h 34m2 stops
$522United Airlines
Sat, Jan 31 - Tue, Feb 3
American Airlines Logo
5:02 pm - 1:50 pm
SYR
-
PTY
20h 48m2 stops
American Airlines Logo
4:05 pm - 11:25 am
PTY
-
SYR
19h 20m2 stops
$622American Airlines
Mon, Feb 16 - Mon, Feb 23
Delta Logo
6:05 am - 12:55 pm
SYR
-
PTY
7h 50m1 stop
Delta Logo
2:20 pm - 11:59 pm
PTY
-
SYR
8h 39m1 stop
$665Delta
Sun, Mar 15 - Thu, Mar 19
Delta Logo
6:05 am - 12:55 pm
SYR
-
PTY
7h 50m1 stop
Delta Logo
2:20 pm - 11:59 pm
PTY
-
SYR
8h 39m1 stop
$711Delta
Sun, Mar 15 - Thu, Mar 19
Delta Logo
6:00 am - 12:55 pm
SYR
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:59 pm
PTY
-
SYR
8h 39m1 stop
$808Delta
Mon, Apr 13 - Sun, Apr 19
United Airlines Logo
7:25 pm - 4:07 pm
SYR
-
PTY
21h 42m2 stops
United Airlines Logo
9:30 am - 8:18 pm
PTY
-
SYR
9h 48m1 stop
$817United Airlines
Sun, Mar 15 - Thu, Mar 19
Multiple Airlines Logo
2:42 pm - 10:30 am
SYR
-
PTY
19h 48m2 stops
Multiple Airlines Logo
2:55 pm - 5:51 pm
PTY
-
SYR
26h 56m3 stops
$909Multiple Airlines
Wed, Jan 28 - Wed, Feb 4
Delta Logo
6:00 am - 1:55 pm
SYR
-
PTY
7h 55m1 stop
Delta Logo
3:20 pm - 11:51 pm
PTY
-
SYR
8h 31m1 stop
$916Delta
Mon, Feb 2 - Mon, Feb 9
Multiple Airlines Logo
11:45 am - 6:28 am
SYR
-
PTY
18h 43m2 stops
Multiple Airlines Logo
7:30 am - 7:19 pm
PTY
-
SYR
11h 49m1 stop
$1,346Multiple Airlines
Mon, Feb 16 - Mon, Feb 23

Delta flights from Syracuse to Panama City

Our best Delta deals on Syracuse to Panama City flight tickets
Delta
Jan 28
SYR6:00 amSyracuse Hancock Intl
7h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Feb 4
PTY3:20 pmPanama City Tocumen Intl
8h 31m
1 stop
SYR11:51 pmSyracuse Hancock Intl
Delta
Mar 15
SYR6:05 amSyracuse Hancock Intl
7h 50m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 19
PTY2:20 pmPanama City Tocumen Intl
8h 39m
1 stop
SYR11:59 pmSyracuse Hancock Intl
Delta
Mar 15
SYR6:05 amSyracuse Hancock Intl
7h 50m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 19
PTY2:20 pmPanama City Tocumen Intl
8h 39m
1 stop
SYR11:59 pmSyracuse Hancock Intl

United Airlines flights from Syracuse to Panama City

Our best United Airlines deals on Syracuse to Panama City flight tickets
United Airlines
Jan 31
SYR4:57 pmSyracuse Hancock Intl
24h 10m
2 stops
PTY5:07 pmPanama City Tocumen Intl
Feb 3
PTY4:41 pmPanama City Tocumen Intl
23h 34m
2 stops
SYR4:15 pmSyracuse Hancock Intl
United Airlines
Mar 15
SYR7:25 pmSyracuse Hancock Intl
21h 42m
2 stops
PTY4:07 pmPanama City Tocumen Intl
Mar 19
PTY9:30 amPanama City Tocumen Intl
9h 48m
1 stop
SYR8:18 pmSyracuse Hancock Intl
United Airlines
Jan 31
SYR10:19 amSyracuse Hancock Intl
10h 16m
1 stop
PTY8:35 pmPanama City Tocumen Intl
Feb 3
PTY9:11 amPanama City Tocumen Intl
9h 31m
1 stop
SYR6:42 pmSyracuse Hancock Intl

momondo Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 1/28

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 2/4

3:20 pm-11:51 pm

1 stop8h 31m

$518

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 1/31

4:57 pm-5:07 pm

2 stops24h 10m

Panama City Tocumen Intl

Tue 2/3

4:41 pm-4:15 pm

2 stops23h 34m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 2/16

5:02 pm-1:50 pm

2 stops20h 48m

Panama City Tocumen Intl

Mon 2/23

4:05 pm-11:25 am

2 stops19h 20m

$622

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 3/15

6:05 am-12:55 pm

1 stop7h 50m

Panama City Tocumen Intl

Thu 3/19

2:20 pm-11:59 pm

1 stop8h 39m

$665

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 3/15

6:05 am-12:55 pm

1 stop7h 50m

Panama City Tocumen Intl

Thu 3/19

2:20 pm-11:59 pm

1 stop8h 39m

$711

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 4/13

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sun 4/19

2:20 pm-11:59 pm

1 stop8h 39m

$808

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sun 3/15

7:25 pm-4:07 pm

2 stops21h 42m

Panama City Tocumen Intl

Thu 3/19

9:30 am-8:18 pm

1 stop9h 48m

$817

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Wed 1/28

2:42 pm-10:30 am

2 stops19h 48m

Panama City Tocumen Intl

Wed 2/4

2:55 pm-5:51 pm

3 stops26h 56m

$909

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 2/2

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Mon 2/9

3:20 pm-11:51 pm

1 stop8h 31m

$916

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Mon 2/16

11:45 am-6:28 am

2 stops18h 43m

Panama City Tocumen Intl

Mon 2/23

7:30 am-7:19 pm

1 stop11h 49m

$1,346

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Syracuse to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from Syracuse to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $377. If you’re not able to fly to Panama City in March, then January is your next best option. Flight prices from Syracuse to Panama City during January average around $490.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Monday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $475. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $739. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Syracuse to Panama City during this time can be as low as $585. Try not to purchase tickets in the afternoon because they tend to be around $890. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Syracuse to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Syracuse to Panama City (SYR to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to Panama City

Fastest flight time

7h 50m

Direct flights

None
The fastest flight from Syracuse to Panama City takes 7h 50m
There are no direct flights from Syracuse to Panama City. There are no popular flight routes from Syracuse to Panama City.
  • How far is Syracuse Hancock Intl to Panama City Tocumen Intl by plane?

    The distance between Syracuse Hancock Intl and Panama City Tocumen Intl is about 2360.8 mi. Typically, this will take 7h 50m by plane in normal conditions.

  • When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Syracuse to Panama City?

Best airlines flying from Syracuse to Panama City

Compare and see reviews for airlines that fly from Syracuse to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $490Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
DeltaPriceFrom $491Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Syracuse to Panama City for you.

Can I find flights from Syracuse to Panama City with flexible booking policies on momondo?

Flights from Syracuse to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Syracuse to Panama City?

Once you have performed a search for Syracuse to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Syracuse to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Syracuse to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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1 adult
Wed 1/14
Wed 1/21

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