Cheap flights from Syracuse to Panama City from $273

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Syracuse to Panama City departing on 3/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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United Airlines Logo
5:48 am - 8:02 pmSYR-PTY
14h 14m2 stops
United Airlines Logo
4:41 pm - 10:00 amPTY-SYR
17h 19m2 stops
$522United Airlines
Find Deal
Thu, Feb 5 - Tue, Feb 17
American Airlines Logo
5:16 pm - 1:21 pmSYR-PTY
20h 05m2 stops
American Airlines Logo
3:50 pm - 10:45 amPTY-SYR
17h 55m2 stops
$624American Airlines
Find Deal
Thu, Mar 5 - Sun, Mar 15
American Airlines Logo
5:00 am - 1:27 pmSYR-PTY
8h 27m1 stop
American Airlines Logo
2:27 pm - 11:26 amPTY-SYR
20h 59m2 stops
$659American Airlines
Find Deal
Sat, Jan 31 - Sat, Feb 7
American Airlines Logo
5:00 am - 1:27 pmSYR-PTY
8h 27m1 stop
American Airlines Logo
2:27 pm - 11:32 pmPTY-SYR
9h 05m1 stop
$752American Airlines
Find Deal
Sat, Jan 31 - Sat, Feb 7
Delta Logo
6:00 am - 1:55 pmSYR-PTY
7h 55m1 stop
Delta Logo
3:27 pm - 11:59 pmPTY-SYR
8h 32m1 stop
$901Delta
Find Deal
Thu, Feb 5 - Tue, Feb 17
United Airlines Logo
6:00 am - 8:02 pmSYR-PTY
14h 02m2 stops
United Airlines Logo
9:30 am - 8:05 pmPTY-SYR
9h 35m1 stop
$1,064United Airlines
Find Deal
Thu, Mar 5 - Sun, Mar 15
Multiple Airlines Logo
6:41 pm - 12:40 amSYR-PTY
29h 59m3 stops
Multiple Airlines Logo
7:50 pm - 2:12 pmPTY-SYR
18h 22m2 stops
$1,088Multiple Airlines
Find Deal
Thu, Feb 5 - Tue, Feb 17
Multiple Airlines Logo
5:48 am - 1:00 amSYR-PTY
19h 12m2 stops
Multiple Airlines Logo
3:50 pm - 10:15 amPTY-SYR
18h 25m3 stops
$1,108Multiple Airlines
Find Deal
Thu, Feb 5 - Tue, Feb 17
Multiple Airlines Logo
8:04 pm - 8:22 amSYR-PTY
12h 18m1 stop
Multiple Airlines Logo
9:34 am - 10:15 amPTY-SYR
24h 41m2 stops
$1,109Multiple Airlines
Find Deal
Thu, Feb 5 - Tue, Feb 17
Delta Logo
6:00 am - 2:02 pmSYR-PTY
8h 02m1 stop
Delta Logo
2:20 pm - 11:59 pmPTY-SYR
8h 39m1 stop
$1,259Delta
Find Deal
Thu, Mar 5 - Sun, Mar 15

United Airlines flights from Syracuse to Panama City

Our best United Airlines deals on Syracuse to Panama City flight tickets
United Airlines
Feb 5
SYR5:48 amSyracuse Hancock Intl
14h 14m
2 stops
PTY8:02 pmPanama City Tocumen Intl
Feb 17
PTY4:41 pmPanama City Tocumen Intl
17h 19m
2 stops
SYR10:00 amSyracuse Hancock Intl
United Airlines
Mar 5
SYR6:00 amSyracuse Hancock Intl
14h 02m
2 stops
PTY8:02 pmPanama City Tocumen Intl
Mar 15
PTY9:30 amPanama City Tocumen Intl
9h 35m
1 stop
SYR8:05 pmSyracuse Hancock Intl
United Airlines
Feb 5
SYR10:19 amSyracuse Hancock Intl
10h 16m
1 stop
PTY8:35 pmPanama City Tocumen Intl
Feb 17
PTY9:11 amPanama City Tocumen Intl
11h 03m
1 stop
SYR8:14 pmSyracuse Hancock Intl

American Airlines flights from Syracuse to Panama City

Our best American Airlines deals on Syracuse to Panama City flight tickets
American Airlines
Mar 5
SYR5:16 pmSyracuse Hancock Intl
20h 05m
2 stops
PTY1:21 pmPanama City Tocumen Intl
Mar 15
PTY3:50 pmPanama City Tocumen Intl
17h 55m
2 stops
SYR10:45 amSyracuse Hancock Intl
American Airlines
Jan 31
SYR5:00 amSyracuse Hancock Intl
8h 27m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 7
PTY2:27 pmPanama City Tocumen Intl
20h 59m
2 stops
SYR11:26 amSyracuse Hancock Intl
American Airlines
Jan 31
SYR5:00 amSyracuse Hancock Intl
8h 27m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 7
PTY2:27 pmPanama City Tocumen Intl
9h 05m
1 stop
SYR11:32 pmSyracuse Hancock Intl

momondo Fare Finder

 
Customize your flight search to find flights from Syracuse to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Syracuse to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 2/5

5:48 am-8:02 pm

2 stops14h 14m

Panama City Tocumen Intl

Tue 2/17

4:41 pm-10:00 am

2 stops17h 19m

$522

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 3/5

5:16 pm-1:21 pm

2 stops20h 05m

Panama City Tocumen Intl

Sun 3/15

3:50 pm-10:45 am

2 stops17h 55m

$624

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 1/31

5:00 am-1:27 pm

1 stop8h 27m

Panama City Tocumen Intl

Sat 2/7

2:27 pm-11:26 am

2 stops20h 59m

$659

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Sat 1/31

5:00 am-1:27 pm

1 stop8h 27m

Panama City Tocumen Intl

Sat 2/7

2:27 pm-11:32 pm

1 stop9h 05m

$752

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 2/5

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 2/17

3:27 pm-11:59 pm

1 stop8h 32m

$901

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 3/5

6:00 am-8:02 pm

2 stops14h 02m

Panama City Tocumen Intl

Sun 3/15

9:30 am-8:05 pm

1 stop9h 35m

$1,064

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 2/5

6:41 pm-12:40 am

3 stops29h 59m

Panama City Tocumen Intl

Tue 2/17

7:50 pm-2:12 pm

2 stops18h 22m

$1,088

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 2/5

5:48 am-1:00 am

2 stops19h 12m

Panama City Tocumen Intl

Tue 2/17

3:50 pm-10:15 am

3 stops18h 25m

$1,108

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 2/5

8:04 pm-8:22 am

1 stop12h 18m

Panama City Tocumen Intl

Tue 2/17

9:34 am-10:15 am

2 stops24h 41m

$1,109

SyracusePanama City

SYR - PTY

SYRPTY

Syracuse Hancock Intl

Thu 3/5

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Sun 3/15

2:20 pm-11:59 pm

1 stop8h 39m

$1,259

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Syracuse to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, November is the cheapest month to fly from Syracuse to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $507. If you’re not able to fly to Panama City in November, then June is your next best option. Flight prices from Syracuse to Panama City during June average around $524.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Monday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $475. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $739. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the morning. Flights from Syracuse to Panama City during this time can be as low as $585. Try not to purchase tickets in the afternoon because they tend to be around $890. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Syracuse to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Syracuse to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Syracuse to Panama City (SYR to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Syracuse to Panama City

Direct flights

None
There are no direct flights from Syracuse to Panama City. There are no popular flight routes from Syracuse to Panama City.
  • How far is Syracuse Hancock Intl to Panama City Tocumen Intl by plane?

    The distance between Syracuse Hancock Intl and Panama City Tocumen Intl is about 2360.8 mi. Typically, this will take 7h 55m by plane in normal conditions.

  • When did momondo last update prices for flights from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Syracuse Hancock Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Syracuse to Panama City?

Best airlines flying from Syracuse to Panama City

Compare and see reviews for airlines that fly from Syracuse to Panama City with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $490Free CancellationRating
7.4
8,997 reviews
Search United Airlines flights
DeltaPriceFrom $491Free CancellationRating
7.9
7,996 reviews
Search Delta flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Syracuse to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Syracuse to Panama City for you.

Can I find flights from Syracuse to Panama City with flexible booking policies on momondo?

Flights from Syracuse to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Syracuse to Panama City?

Once you have performed a search for Syracuse to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Syracuse to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Syracuse to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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1 adult
Wed 11/26
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