Cheap flights from Santo Domingo to Mexico City from $224

The cheapest month to fly to Mexico City Benito Juarez Airport from Santo Domingo is in April. Flight prices, which tend to average around $407, are often lower during this time because this is during the off-season. If you don’t want to visit Mexico City Benito Juarez Airport in April, then you should wait until January to fly from Santo Domingo, when ticket prices are also cheap, with an average price of $419.

The cheapest day to depart from Santo Domingo to Mexico City Benito Juarez Airport is on a Thursday. Travelers who choose to depart for Mexico City Benito Juarez Airport on a Thursday will often find tickets for as low as $476. Flights from Santo Domingo to Mexico City Benito Juarez Airport on a Monday will generally be more expensive and average around $724. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Fly from Santo Domingo Las Americas to Mexico City Benito Juarez for the best Santo Domingo Las Americas - Mexico City Benito Juarez flight prices

You are more likely to see cheaper flights to Mexico City Benito Juarez Airport from Santo Domingo when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico City Benito Juarez Airport for around $452 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico City Benito Juarez Airport from Santo Domingo for as low as $376 on momondo.

There are 3 cabin classes available to choose from on Santo Domingo to Mexico City Benito Juarez Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 21% on your flight if you consider stops on a Santo Domingo to Mexico City Benito Juarez Airport flight.

Copa Airlines and Avianca are the most popular carriers operating from Santo Domingo Las Americas to Mexico City Benito Juarez

Aeromexico, Arajet and Copa Airlines are the top three most popular airlines that fly to Mexico City Benito Juarez Airport from Santo Domingo according to our data. Aeromexico is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Mexico City Benito Juarez Airport. Keep in mind that there are 3 different airlines that fly to Mexico City Benito Juarez Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 1% of flights between Santo Domingo and Mexico City have experienced a delay on any given week. The average delay length over the past 12 months has been 151 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, Aeromexico have had the least number of delays on this route over the last 12 months; with about 1% of their flights experiencing any sort of delay.

As of November 2026, 1 flights take off from Santo Domingo and land in Mexico City Benito Juarez Airport each day. The most common flight departure time for this route is 11:00AM, with 100% of daily flights taking off at noon.

As of November 2026, there are 7 flights per week flying from Santo Domingo to Mexico City Benito Juarez Airport. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.