Cheap flights from Santo Domingo to Mexico City from $168

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Mexico City departing on 12/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
12:40 pm - 10:05 pm
SDQ
-
MEX
11h 25m1 stop
Copa Airlines Logo
1:20 am - 1:09 pm
MEX
-
SDQ
9h 49m1 stop
$356Copa Airlines
mié., dic. 24 - jue., ene. 22
Copa Airlines Logo
12:40 pm - 7:20 pm
SDQ
-
MEX
8h 40m1 stop
Copa Airlines Logo
9:25 am - 10:55 pm
MEX
-
SDQ
11h 30m1 stop
$380Copa Airlines
mié., dic. 31 - mié., ene. 7
Copa Airlines Logo
12:40 pm - 7:20 pm
SDQ
-
MEX
8h 40m1 stop
Copa Airlines Logo
1:10 pm - 10:55 pm
MEX
-
SDQ
7h 45m1 stop
$386Copa Airlines
mié., ene. 21 - mié., ene. 28
Copa Airlines Logo
11:57 am - 7:20 pm
SDQ
-
MEX
9h 23m1 stop
Copa Airlines Logo
5:55 am - 6:05 pm
MEX
-
SDQ
10h 10m1 stop
$391Copa Airlines
jue., feb. 5 - jue., feb. 12
Aeromexico Logo
11:07 am - 2:10 pm
SDQ
-
MEX
5h 03mnonstop
Aeromexico Logo
1:05 am - 7:18 am
MEX
-
SDQ
4h 13mnonstop
$394Aeromexico
sáb., feb. 14 - vie., feb. 20
Copa Airlines Logo
12:40 pm - 7:20 pm
SDQ
-
MEX
8h 40m1 stop
Copa Airlines Logo
3:30 pm - 6:05 pm
MEX
-
SDQ
24h 35m1 stop
$399Copa Airlines
jue., dic. 25 - jue., ene. 1
Copa Airlines Logo
6:00 am - 10:05 pm
SDQ
-
MEX
18h 05m1 stop
Copa Airlines Logo
9:25 am - 10:55 pm
MEX
-
SDQ
11h 30m1 stop
$401Copa Airlines
mar., dic. 30 - mar., ene. 6
Copa Airlines Logo
6:00 am - 7:20 pm
SDQ
-
MEX
15h 20m1 stop
Copa Airlines Logo
9:25 am - 10:55 pm
MEX
-
SDQ
11h 30m1 stop
$403Copa Airlines
jue., ene. 15 - jue., ene. 22
Multiple Airlines Logo
8:50 am - 2:30 pm
SDQ
-
MEX
7h 40m1 stop
Multiple Airlines Logo
12:40 am - 11:25 am
MEX
-
SDQ
8h 45m1 stop
$404Multiple Airlines
jue., ene. 22 - mié., ene. 28
Multiple Airlines Logo
6:00 am - 12:15 am
SDQ
-
MEX
20h 15m1 stop
Multiple Airlines Logo
12:40 am - 11:25 am
MEX
-
SDQ
8h 45m1 stop
$405Multiple Airlines
jue., ene. 15 - mié., ene. 21

Copa Airlines flights from Santo Domingo to Mexico City

Our best Copa Airlines deals on Santo Domingo to Mexico City flight tickets
Copa Airlines
Dec 24
SDQ12:40 pmSanto Domingo Las Americas
11h 25m
1 stop
MEX10:05 pmMexico City Benito Juarez
Jan 22
MEX1:20 amMexico City Benito Juarez
9h 49m
1 stop
SDQ1:09 pmSanto Domingo Las Americas
Copa Airlines
Dec 31
SDQ12:40 pmSanto Domingo Las Americas
8h 40m
1 stop
MEX7:20 pmMexico City Benito Juarez
Jan 7
MEX9:25 amMexico City Benito Juarez
11h 30m
1 stop
SDQ10:55 pmSanto Domingo Las Americas
Copa Airlines
May 13
SDQ8:45 amSanto Domingo Las Americas
12h 20m
1 stop
MEX7:05 pmMexico City Benito Juarez
May 20
MEX9:50 amMexico City Benito Juarez
14h 35m
1 stop
SDQ2:25 amSanto Domingo Las Americas

Aeromexico flights from Santo Domingo to Mexico City

Our best Aeromexico deals on Santo Domingo to Mexico City flight tickets
Aeromexico
Apr 15
SDQ11:12 amSanto Domingo Las Americas
4h 43m
MEX1:55 pmMexico City Benito Juarez
Apr 21
MEX12:15 amMexico City Benito Juarez
4h 27m
SDQ6:42 amSanto Domingo Las Americas
Aeromexico
Jan 16
SDQ11:01 amSanto Domingo Las Americas
4h 54m
MEX1:55 pmMexico City Benito Juarez
Jan 22
MEX1:05 amMexico City Benito Juarez
4h 13m
SDQ7:18 amSanto Domingo Las Americas
Aeromexico
Feb 2
SDQ11:01 amSanto Domingo Las Americas
4h 54m
MEX1:55 pmMexico City Benito Juarez
Feb 8
MEX1:05 amMexico City Benito Juarez
4h 13m
SDQ7:18 amSanto Domingo Las Americas

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 17, 2025.
Use the filters below to find and compare flights from Santo Domingo to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

mié. 12/24

12:40 pm-10:05 pm

1 stop11h 25m

Mexico City Benito Juarez

jue. 1/22

1:20 am-1:09 pm

1 stop9h 49m

$356

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

mié. 12/31

12:40 pm-7:20 pm

1 stop8h 40m

Mexico City Benito Juarez

mié. 1/7

9:25 am-10:55 pm

1 stop11h 30m

$380

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

mié. 1/21

12:40 pm-7:20 pm

1 stop8h 40m

Mexico City Benito Juarez

mié. 1/28

1:10 pm-10:55 pm

1 stop7h 45m

$386

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

jue. 2/5

11:57 am-7:20 pm

1 stop9h 23m

Mexico City Benito Juarez

jue. 2/12

5:55 am-6:05 pm

1 stop10h 10m

$391

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

sáb. 2/14

11:07 am-2:10 pm

Nonstop5h 03m

Mexico City Benito Juarez

vie. 2/20

1:05 am-7:18 am

Nonstop4h 13m

$394

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

jue. 12/25

12:40 pm-7:20 pm

1 stop8h 40m

Mexico City Benito Juarez

jue. 1/1

3:30 pm-6:05 pm

1 stop24h 35m

$399

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

mar. 12/30

6:00 am-10:05 pm

1 stop18h 05m

Mexico City Benito Juarez

mar. 1/6

9:25 am-10:55 pm

1 stop11h 30m

$401

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

jue. 1/15

6:00 am-7:20 pm

1 stop15h 20m

Mexico City Benito Juarez

jue. 1/22

9:25 am-10:55 pm

1 stop11h 30m

$403

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

jue. 1/22

8:50 am-2:30 pm

1 stop7h 40m

Mexico City Benito Juarez

mié. 1/28

12:40 am-11:25 am

1 stop8h 45m

$404

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

jue. 1/15

6:00 am-12:15 am

1 stop20h 15m

Mexico City Benito Juarez

mié. 1/21

12:40 am-11:25 am

1 stop8h 45m

$405

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City from

How to get the cheapest flight ticket from Santo Domingo to Mexico City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City?

The cheapest month to fly to Mexico City from Santo Domingo is in October. Flight prices, which tend to average around $346, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of October, then book flights to Mexico City from Santo Domingo during August instead. Flights to Mexico City in August, while not as cheap as those in October, still average around $351.

What is the cheapest day to depart on your flight to Mexico City?

Our data shows that Friday is the least expensive day to fly to Mexico City. Tickets to fly out on this day can be as low as $428. On the other hand, Wednesday is the most expensive day to depart from Santo Domingo because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $588.

What is the cheapest time of day to depart on your flight to Mexico City?

According to our data, the cheapest time of day to fly to Mexico City is in the evening. momondo users have found flights departing from Santo Domingo to Mexico City in the evening for as low as $199. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Mexico City, so prices are often more expensive at around $503 per ticket.

What is the cheapest Santo Domingo Las Americas to Mexico City Benito Juarez flight route?

Fly from Santo Domingo Las Americas to Mexico City Benito Juarez for the best Santo Domingo Las Americas - Mexico City Benito Juarez flight prices

How far in advance should I book a flight to Mexico City?

You are more likely to see cheaper flights to Mexico City from Santo Domingo when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico City for around $375 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico City from Santo Domingo for as low as $299 on momondo.

What cabin class options are available on Santo Domingo Las Americas to Mexico City Benito Juarez flights?

There are 3 cabin classes available to choose from on Santo Domingo Las Americas to Mexico City Benito Juarez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santo Domingo to Mexico City flights?

No. A direct flight is the cheapest option for a flight between Santo Domingo to Mexico City.

How have Santo Domingo to Mexico City flight prices changed over time?

As of December 2025, prices for Santo Domingo to Mexico City flights are approximately 10% more expensive when compared to flights at the same time last year.

When to book flights from Santo Domingo to Mexico City

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Mexico City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Mexico City (SDQ to MEX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Mexico City

Best Price Found

$579

Fastest flight time

4h 55m

Direct flights

Every day

Airports in Mexico City

1 airport
The best one-way flight to Mexico City from Santo Domingo in the past 72 hours is $579. The best round-trip flight deal from Santo Domingo to Mexico City found on momondo in the last 72 hours is $372.
The fastest flight from Santo Domingo to Mexico City takes 4h 55m
Direct flights go from Santo Domingo to Mexico City every day.
There is 1 airport in Mexico City. From Santo Domingo there are direct flights to Mexico City Benito Juarez (MEX).
  • How far is Santo Domingo Las Americas to Mexico City Benito Juarez by plane?

    Mexico City Benito Juarez is 1907.2 mi away from Santo Domingo Las Americas. A reasonable flight in good conditions will take 4h 55m.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport refresh daily.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport.

  • What documentation or ID do you need to fly to Mexico City Benito Juarez Airport?

    The necessary travel and health documents for your Mexico City Benito Juarez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santo Domingo to Mexico City?

  • What is the most popular airline from Santo Domingo to Mexico City?

Best airlines flying from Santo Domingo to Mexico City

Compare and see reviews for airlines that fly from Santo Domingo to Mexico City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $166Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights
ArajetPriceFrom $178Free CancellationRating
6.8
38 reviews
Search Arajet flights
AeromexicoPriceFrom $238Free CancellationRating
7.4
1,629 reviews
Search Aeromexico flights
  • Aeromexico Flights From Santo Domingo to Mexico City

    Across 7 Aeromexico flights from Santo Domingo to Mexico City this week, the average price was $442, with the best Aeromexico deals starting from $238 round-trip. 1,629 users have rated Aeromexico on momondo, with an average score of 7.4/10.

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Cuernavaca
Tepoztlán
Taxco
Valle de Bravo

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Mexico City?

It is quick and easy to find Santo Domingo to Mexico City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Mexico City that suits you.

Can I find flights from Santo Domingo to Mexico City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santo Domingo to Mexico City flights to just show those with flexible booking policies.

How can momondo help me find flights from Santo Domingo to Mexico City?

momondo helps you find the best flight between Santo Domingo and Mexico City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to Mexico City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santo Domingo to Mexico City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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vie. 1/16
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