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Cheap flights from Santo Domingo to Mexico City from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Mexico City departing on 3/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santo Domingo to Mexico City

Cheap round-trip flights

Aeromexico Logo
11:01 am - 1:50 pmSDQ-MEX
4h 49mnonstop
Aeromexico Logo
12:30 am - 6:50 amMEX-SDQ
4h 20mnonstop
$337Aeromexico
Find Deal
Tue, Oct 14 - Mon, Oct 20
Copa Airlines Logo
8:55 am - 1:00 amSDQ-MEX
18h 05m1 stop
Copa Airlines Logo
9:25 am - 2:26 amMEX-SDQ
15h 01m1 stop
$353Copa Airlines
Find Deal
Tue, Nov 4 - Wed, Nov 19
Copa Airlines Logo
8:58 am - 10:05 pmSDQ-MEX
15h 07m1 stop
Copa Airlines Logo
1:40 am - 4:15 pmMEX-SDQ
12h 35m1 stop
$374Copa Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21
Avianca Logo
12:20 pm - 10:55 pmSDQ-MEX
12h 35m1 stop
Avianca Logo
11:15 pm - 4:50 pmMEX-SDQ
15h 35m1 stop
$376Avianca
Find Deal
Thu, Nov 20 - Mon, Nov 24
Copa Airlines Logo
11:56 am - 12:15 amSDQ-MEX
14h 19m1 stop
Copa Airlines Logo
1:20 am - 1:11 pmMEX-SDQ
9h 51m1 stop
$382Copa Airlines
Find Deal
Tue, Mar 3 - Wed, Mar 11
Aeromexico Logo
11:01 am - 1:50 pmSDQ-MEX
4h 49mnonstop
Aeromexico Logo
1:01 am - 7:21 amMEX-SDQ
4h 20mnonstop
$385Aeromexico
Find Deal
Fri, Oct 24 - Wed, Nov 5
Copa Airlines Logo
8:58 am - 10:05 pmSDQ-MEX
15h 07m1 stop
Copa Airlines Logo
1:40 am - 1:07 pmMEX-SDQ
9h 27m1 stop
$392Copa Airlines
Find Deal
Wed, Oct 1 - Sat, Oct 18
Copa Airlines Logo
5:25 am - 2:30 pmSDQ-MEX
11h 05m1 stop
Copa Airlines Logo
3:30 pm - 10:56 amMEX-SDQ
17h 26m1 stop
$409Copa Airlines
Find Deal
Tue, Sep 30 - Wed, Oct 8
Copa Airlines Logo
8:55 am - 12:15 amSDQ-MEX
17h 20m1 stop
Copa Airlines Logo
9:25 am - 2:26 amMEX-SDQ
15h 01m1 stop
$412Copa Airlines
Find Deal
Tue, Nov 4 - Wed, Nov 19
Avianca Logo
5:45 pm - 3:00 amSDQ-MEX
11h 15m1 stop
Avianca Logo
11:15 pm - 4:50 pmMEX-SDQ
15h 35m1 stop
$428Avianca
Find Deal
Tue, Nov 18 - Mon, Nov 24

Copa Airlines flights from Santo Domingo to Mexico City

Our best Copa Airlines deals on Santo Domingo to Mexico City flight tickets
Copa Airlines
Nov 4
SDQ8:55 amSanto Domingo Las Americas
18h 05m
1 stop
MEX1:00 amMexico City Benito Juarez
Nov 19
MEX9:25 amMexico City Benito Juarez
15h 01m
1 stop
SDQ2:26 amSanto Domingo Las Americas
$353
Find similar
Copa Airlines
Oct 14
SDQ8:58 amSanto Domingo Las Americas
15h 07m
1 stop
MEX10:05 pmMexico City Benito Juarez
Oct 21
MEX1:40 amMexico City Benito Juarez
12h 35m
1 stop
SDQ4:15 pmSanto Domingo Las Americas
$374
Find similar
Copa Airlines
Mar 3
SDQ11:56 amSanto Domingo Las Americas
14h 19m
1 stop
MEX12:15 amMexico City Benito Juarez
Mar 11
MEX1:20 amMexico City Benito Juarez
9h 51m
1 stop
SDQ1:11 pmSanto Domingo Las Americas
$382
Find similar

Avianca flights from Santo Domingo to Mexico City

Our best Avianca deals on Santo Domingo to Mexico City flight tickets
Avianca
Nov 20
SDQ12:20 pmSanto Domingo Las Americas
12h 35m
1 stop
MEX10:55 pmMexico City Benito Juarez
Nov 24
MEX11:15 pmMexico City Benito Juarez
15h 35m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
$376
Find similar
Avianca
Nov 18
SDQ5:45 pmSanto Domingo Las Americas
11h 15m
1 stop
MEX3:00 amMexico City Benito Juarez
Nov 24
MEX11:15 pmMexico City Benito Juarez
15h 35m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
$428
Find similar
Avianca
Nov 20
SDQ12:20 pmSanto Domingo Las Americas
15h 35m
2 stops
MEX1:55 amMexico City Benito Juarez
Nov 24
MEX11:15 pmMexico City Benito Juarez
15h 35m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
$446
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Santo Domingo to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 10/14

11:01 am-1:50 pm

Nonstop4h 49m

Mexico City Benito Juarez

Mon 10/20

12:30 am-6:50 am

Nonstop4h 20m

$337

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 11/4

8:55 am-1:00 am

1 stop18h 05m

Mexico City Benito Juarez

Wed 11/19

9:25 am-2:26 am

1 stop15h 01m

$353

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 10/14

8:58 am-10:05 pm

1 stop15h 07m

Mexico City Benito Juarez

Tue 10/21

1:40 am-4:15 pm

1 stop12h 35m

$374

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Thu 11/20

12:20 pm-10:55 pm

1 stop12h 35m

Mexico City Benito Juarez

Mon 11/24

11:15 pm-4:50 pm

1 stop15h 35m

$376

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 3/3

11:56 am-12:15 am

1 stop14h 19m

Mexico City Benito Juarez

Wed 3/11

1:20 am-1:11 pm

1 stop9h 51m

$382

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Fri 10/24

11:01 am-1:50 pm

Nonstop4h 49m

Mexico City Benito Juarez

Wed 11/5

1:01 am-7:21 am

Nonstop4h 20m

$385

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 10/1

8:58 am-10:05 pm

1 stop15h 07m

Mexico City Benito Juarez

Sat 10/18

1:40 am-1:07 pm

1 stop9h 27m

$392

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 9/30

5:25 am-2:30 pm

1 stop11h 05m

Mexico City Benito Juarez

Wed 10/8

3:30 pm-10:56 am

1 stop17h 26m

$409

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 11/4

8:55 am-12:15 am

1 stop17h 20m

Mexico City Benito Juarez

Wed 11/19

9:25 am-2:26 am

1 stop15h 01m

$412

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 11/18

5:45 pm-3:00 am

1 stop11h 15m

Mexico City Benito Juarez

Mon 11/24

11:15 pm-4:50 pm

1 stop15h 35m

$428

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City from

How to get the cheapest flight ticket from Santo Domingo to Mexico City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santo Domingo and Mexico City?

What is the cheapest month to fly to Mexico City?

The cheapest month to fly to Mexico City from Santo Domingo is in August. Flight prices, which tend to average around $351, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to Mexico City from Santo Domingo during June instead. Flights to Mexico City in June, while not as cheap as those in August, still average around $354.

What is the cheapest day to depart on your flight to Mexico City?

Our data shows that Friday is the least expensive day to fly to Mexico City. Tickets to fly out on this day can be as low as $443. On the other hand, Wednesday is the most expensive day to depart from Santo Domingo because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $588.

What is the cheapest time of day to depart on your flight to Mexico City?

According to our data, the cheapest time of day to fly to Mexico City is in the evening. momondo users have found flights departing from Santo Domingo to Mexico City in the evening for as low as $199. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the morning is when there is more demand to fly to Mexico City, so prices are often more expensive at around $527 per ticket.

What is the cheapest Santo Domingo Las Americas to Mexico City Benito Juarez flight route?

Fly from Santo Domingo Las Americas to Mexico City Benito Juarez for the best Santo Domingo Las Americas - Mexico City Benito Juarez flight prices

How far in advance should I book a flight to Mexico City?

You are more likely to see cheaper flights to Mexico City from Santo Domingo when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico City for around $377 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico City from Santo Domingo for as low as $303 on momondo.

What cabin class options are available on Santo Domingo Las Americas to Mexico City Benito Juarez flights?

There are 3 cabin classes available to choose from on Santo Domingo Las Americas to Mexico City Benito Juarez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santo Domingo to Mexico City flights?

No. A direct flight is the cheapest option for a flight between Santo Domingo to Mexico City.

How have Santo Domingo to Mexico City flight prices changed over time?

As of September 2025, prices for Santo Domingo to Mexico City flights are approximately 20% more expensive when compared to flights at the same time last year.

When to book flights from Santo Domingo to Mexico City

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Mexico City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Mexico City (SDQ to MEX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Mexico City

Best Price Found

$211

Fastest flight time

4h 44m

Direct flights

Tue, Wed, Thu, Fri, Sat and Sun

Airports in Mexico City

1 airport
The best one-way flight to Mexico City from Santo Domingo in the past 72 hours is $211. The best round-trip flight deal from Santo Domingo to Mexico City found on momondo in the last 72 hours is $351.
The fastest flight from Santo Domingo to Mexico City takes 4h 44m
Direct flights go from Santo Domingo to Mexico City on Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday. The only airline offering direct flights is Aeromexico.
There is 1 airport near Mexico City: Mexico City Benito Juarez (MEX)
Search flight deals

  • How far is Santo Domingo Las Americas to Mexico City Benito Juarez by plane?

    Mexico City Benito Juarez is 1907.2 mi away from Santo Domingo Las Americas. A reasonable flight in good conditions will take 4h 44m.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport refresh daily.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to Mexico City Benito Juarez Airport.

  • What documentation or ID do you need to fly to Mexico City Benito Juarez Airport?

    The necessary travel and health documents for your Mexico City Benito Juarez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santo Domingo to Mexico City?

  • What is the most popular airline from Santo Domingo to Mexico City?

Best airlines flying from Santo Domingo to Mexico City

Compare and see reviews for airlines that fly from Santo Domingo to Mexico City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $166Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
ArajetPriceFrom $199Free CancellationRating
7.0
34 reviews
Search Arajet flights
AeromexicoPriceFrom $212Free CancellationRating
7.4
1,696 reviews
Search Aeromexico flights

  • Aeromexico Flights From Santo Domingo to Mexico City

    Across 6 Aeromexico flights from Santo Domingo to Mexico City this week, the average price was $440, with the best Aeromexico deals starting from $212 round-trip. 1,696 users have rated Aeromexico on momondo, with an average score of 7.4/10.

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Cuernavaca
Tepoztlán
Taxco
Valle de Bravo

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Mexico City?

It is quick and easy to find Santo Domingo to Mexico City flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Mexico City that suits you.

Can I find flights from Santo Domingo to Mexico City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santo Domingo to Mexico City flights to just show those with flexible booking policies.

How can momondo help me find flights from Santo Domingo to Mexico City?

momondo helps you find the best flight between Santo Domingo and Mexico City by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santo Domingo to Mexico City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Santo Domingo to Mexico City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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