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Cheap flights from Santiago to Santo Domingo from $292

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Santo Domingo departing on 6/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santiago to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
Multiple Airlines Logo
8:55 am - 10:55 pm
SDQ
-
SCL
14h 00m
1 stop
$464Multiple Airlines
Mon, May 25 - Fri, May 29
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
Multiple Airlines Logo
1:45 pm - 2:35 am
SDQ
-
SCL
12h 50m
1 stop
$474Multiple Airlines
Mon, Jul 6 - Tue, Jul 14
Multiple Airlines Logo
3:35 am - 3:45 pm
SCL
-
SDQ
12h 10m
1 stop
Multiple Airlines Logo
8:55 am - 10:55 pm
SDQ
-
SCL
14h 00m
1 stop
$503Multiple Airlines
Thu, May 28 - Fri, Jun 5
Multiple Airlines Logo
3:35 am - 3:45 pm
SCL
-
SDQ
12h 10m
1 stop
Multiple Airlines Logo
8:55 am - 10:55 pm
SDQ
-
SCL
14h 00m
1 stop
$562Multiple Airlines
Thu, May 28 - Fri, Jun 5
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
Multiple Airlines Logo
1:55 pm - 3:55 am
SDQ
-
SCL
14h 00m
1 stop
$576Multiple Airlines
Mon, May 25 - Sun, May 31
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
Multiple Airlines Logo
8:55 am - 10:55 pm
SDQ
-
SCL
14h 00m
1 stop
$594Multiple Airlines
Mon, May 25 - Fri, Jun 12
Multiple Airlines Logo
3:35 am - 3:45 pm
SCL
-
SDQ
12h 10m
1 stop
Multiple Airlines Logo
8:55 am - 10:55 pm
SDQ
-
SCL
14h 00m
1 stop
$595Multiple Airlines
Thu, May 7 - Fri, May 29
Multiple Airlines Logo
5:00 am - 4:55 pm
SCL
-
SDQ
11h 55m
1 stop
Multiple Airlines Logo
1:45 pm - 2:35 am
SDQ
-
SCL
12h 50m
1 stop
$602Multiple Airlines
Mon, Jul 6 - Tue, Jul 14
Multiple Airlines Logo
3:35 am - 3:45 pm
SCL
-
SDQ
12h 10m
1 stop
Multiple Airlines Logo
3:25 pm - 3:55 am
SDQ
-
SCL
12h 30m
1 stop
$615Multiple Airlines
Thu, Aug 6 - Sun, Aug 16
Avianca Logo
1:30 am - 11:50 am
SCL
-
SDQ
11h 20m
1 stop
Avianca Logo
6:50 pm - 5:45 am
SDQ
-
SCL
9h 55m
1 stop
$637Avianca
Mon, Oct 12 - Sun, Oct 18

Copa Airlines flights from Santiago to Santo Domingo

Our best Copa Airlines deals on Santiago to Santo Domingo flight tickets
Copa Airlines
Apr 29
SCL11:25 amSantiago Arturo Merino Benitez
14h 55m
1 stop
SDQ2:20 amSanto Domingo Las Americas
May 3
SDQ12:40 pmSanto Domingo Las Americas
10h 46m
1 stop
SCL11:26 pmSantiago Arturo Merino Benitez
$660
Copa Airlines
Jun 17
SCL11:17 amSantiago Arturo Merino Benitez
11h 39m
1 stop
SDQ10:56 pmSanto Domingo Las Americas
Aug 2
SDQ6:07 amSanto Domingo Las Americas
13h 16m
1 stop
SCL7:23 pmSantiago Arturo Merino Benitez
$683
Copa Airlines
Jun 22
SCL11:17 amSantiago Arturo Merino Benitez
15h 08m
1 stop
SDQ2:25 amSanto Domingo Las Americas
Aug 6
SDQ12:13 pmSanto Domingo Las Americas
11h 13m
1 stop
SCL11:26 pmSantiago Arturo Merino Benitez
$714

Avianca flights from Santiago to Santo Domingo

Our best Avianca deals on Santiago to Santo Domingo flight tickets
Avianca
Oct 12
SCL1:30 amSantiago Arturo Merino Benitez
11h 20m
1 stop
SDQ11:50 amSanto Domingo Las Americas
Oct 18
SDQ6:50 pmSanto Domingo Las Americas
9h 55m
1 stop
SCL5:45 amSantiago Arturo Merino Benitez
$637
Avianca
Apr 18
SCL12:30 amSantiago Arturo Merino Benitez
11h 20m
1 stop
SDQ11:50 amSanto Domingo Las Americas
May 21
SDQ6:50 pmSanto Domingo Las Americas
9h 55m
1 stop
SCL4:45 amSantiago Arturo Merino Benitez
$648
Avianca
May 19
SCL12:30 amSantiago Arturo Merino Benitez
17h 25m
1 stop
SDQ5:55 pmSanto Domingo Las Americas
Jun 1
SDQ6:50 pmSanto Domingo Las Americas
9h 55m
1 stop
SCL4:45 amSantiago Arturo Merino Benitez
$658

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 5/25

5:00 am-4:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Fri 5/29

8:55 am-10:55 pm

1 stop14h 00m

$464

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 7/6

5:00 am-4:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Tue 7/14

1:45 pm-2:35 am

1 stop12h 50m

$474

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 5/28

3:35 am-3:45 pm

1 stop12h 10m

Santo Domingo Las Americas

Fri 6/5

8:55 am-10:55 pm

1 stop14h 00m

$503

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 5/28

3:35 am-3:45 pm

1 stop12h 10m

Santo Domingo Las Americas

Fri 6/5

8:55 am-10:55 pm

1 stop14h 00m

$562

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 5/25

5:00 am-4:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Sun 5/31

1:55 pm-3:55 am

1 stop14h 00m

$576

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 5/25

5:00 am-4:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Fri 6/12

8:55 am-10:55 pm

1 stop14h 00m

$594

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 5/7

3:35 am-3:45 pm

1 stop12h 10m

Santo Domingo Las Americas

Fri 5/29

8:55 am-10:55 pm

1 stop14h 00m

$595

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 7/6

5:00 am-4:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Tue 7/14

1:45 pm-2:35 am

1 stop12h 50m

$602

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 8/6

3:35 am-3:45 pm

1 stop12h 10m

Santo Domingo Las Americas

Sun 8/16

3:25 pm-3:55 am

1 stop12h 30m

$615
Quickest round-trip

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 10/12

1:30 am-11:50 am

1 stop11h 20m

Santo Domingo Las Americas

Sun 10/18

6:50 pm-5:45 am

1 stop9h 55m

$637

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Santiago to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in August, then you should wait until September to fly from Santiago, when ticket prices are also cheap, with an average price of $535.

What is the cheapest Santiago Arturo Merino Benitez to Santo Domingo Las Americas flight route?

Fly from Santiago Arturo Merino Benitez to Santo Domingo Las Americas for the best Santiago Arturo Merino Benitez - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $582 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Santiago for as low as $564 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Santo Domingo Las Americas flights?

There is only 1 cabin class available to choose from on Santiago Arturo Merino Benitez to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Santo Domingo flights?

No. A direct flight is the cheapest option for a flight between Santiago to Santo Domingo.

How have Santiago to Santo Domingo flight prices changed over time?

As of April 2026, prices for Santiago to Santo Domingo flights are approximately 44% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Santo Domingo (SCL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Santo Domingo

Fastest flight time

11h 15m

Direct flights

None
The fastest flight from Santiago to Santo Domingo takes 11h 15m
There are no direct flights from Santiago to Santo Domingo. There are no popular flight routes from Santiago to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Santiago to Santo Domingo

  • How far is Santiago Arturo Merino Benitez to Santo Domingo Las Americas by plane?

    The distance between Santiago Arturo Merino Benitez and Santo Domingo Las Americas is about 3586.0 mi. 11h 15m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to Santo Domingo?

Best airlines flying from Santiago to Santo Domingo

Compare and see reviews for airlines that fly from Santiago to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $502Free CancellationRating
6.5
2,511 reviews
Search Avianca flights
Copa AirlinesPriceFrom $515Free CancellationRating
7.5
1,575 reviews
Search Copa Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Santiago.

Can I find flights from Santiago to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Santiago.

I’m not ready to book a flight from Santiago to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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