Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Santiago to Santo Domingo from $250

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Santo Domingo departing on 9/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santiago to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
3:48 am - 2:08 am
SCL
-
SDQ
23h 20m
1 stop
Copa Airlines Logo
8:55 am - 8:11 pm
SDQ
-
SCL
10h 16m
1 stop
$574Copa Airlines
Fri, Dec 4 - Thu, Dec 10
Copa Airlines Logo
12:06 am - 1:13 pm
SCL
-
SDQ
13h 07m
1 stop
Copa Airlines Logo
8:47 am - 12:22 am
SDQ
-
SCL
14h 35m
1 stop
$574Copa Airlines
Wed, Sep 2 - Thu, Sep 10
Copa Airlines Logo
1:02 am - 11:45 am
SCL
-
SDQ
11h 43m
1 stop
Copa Airlines Logo
7:06 pm - 5:46 am
SDQ
-
SCL
9h 40m
1 stop
$574Copa Airlines
Tue, Nov 3 - Wed, Nov 4
Copa Airlines Logo
3:14 am - 4:15 pm
SCL
-
SDQ
14h 01m
1 stop
Copa Airlines Logo
8:47 am - 3:56 am
SDQ
-
SCL
18h 09m
1 stop
$574Copa Airlines
Tue, Sep 22 - Fri, Sep 25
Multiple Airlines Logo
9:25 am - 9:40 pm
SCL
-
SDQ
13h 15m
1 stop
Multiple Airlines Logo
3:55 pm - 4:55 am
SDQ
-
SCL
12h 00m
1 stop
$626Multiple Airlines
Sat, Dec 19 - Sun, Jan 10
Avianca Logo
1:30 am - 11:50 am
SCL
-
SDQ
11h 20m
1 stop
Avianca Logo
6:50 pm - 5:45 am
SDQ
-
SCL
9h 55m
1 stop
$657Avianca
Mon, Oct 12 - Sun, Oct 18
Avianca Logo
7:40 am - 5:55 pm
SCL
-
SDQ
11h 15m
1 stop
Avianca Logo
12:45 pm - 12:20 am
SDQ
-
SCL
10h 35m
1 stop
$657Avianca
Tue, Oct 13 - Sun, Oct 18
Avianca Logo
6:40 am - 5:55 pm
SCL
-
SDQ
11h 15m
1 stop
Avianca Logo
6:50 pm - 4:45 am
SDQ
-
SCL
9h 55m
1 stop
$657Avianca
Mon, Aug 17 - Mon, Aug 24
Multiple Airlines Logo
1:11 am - 11:57 pm
SCL
-
SDQ
22h 46m
1 stop
Multiple Airlines Logo
9:00 pm - 5:08 am
SDQ
-
SCL
31h 08m
1 stop
$670Multiple Airlines
Thu, Sep 3 - Thu, Sep 24
Multiple Airlines Logo
11:05 pm - 11:57 pm
SCL
-
SDQ
24h 52m
2 stops
Multiple Airlines Logo
5:55 pm - 9:55 pm
SDQ
-
SCL
28h 00m
3 stops
$697Multiple Airlines
Thu, Aug 13 - Sun, Aug 16

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Copa Airlines flights from Santiago to Santo Domingo

Our best Copa Airlines deals on Santiago to Santo Domingo flight tickets
Copa Airlines
Sep 21
SCL12:22 pmSantiago Arturo Merino Benitez
15h 03m
1 stop
SDQ2:25 amSanto Domingo Las Americas
Sep 28
SDQ12:42 pmSanto Domingo Las Americas
13h 04m
1 stop
SCL2:46 amSantiago Arturo Merino Benitez
$574
Copa Airlines
Nov 30
SCL1:07 amSantiago Arturo Merino Benitez
16h 06m
1 stop
SDQ4:13 pmSanto Domingo Las Americas
Dec 31
SDQ12:09 pmSanto Domingo Las Americas
14h 37m
1 stop
SCL3:46 amSantiago Arturo Merino Benitez
$627
Copa Airlines
Dec 9
SCL3:19 amSantiago Arturo Merino Benitez
13h 54m
1 stop
SDQ4:13 pmSanto Domingo Las Americas
Jan 7
SDQ7:05 pmSanto Domingo Las Americas
9h 52m
1 stop
SCL5:57 amSantiago Arturo Merino Benitez
$650

Avianca flights from Santiago to Santo Domingo

Our best Avianca deals on Santiago to Santo Domingo flight tickets
Avianca
Oct 13
SCL7:40 amSantiago Arturo Merino Benitez
11h 15m
1 stop
SDQ5:55 pmSanto Domingo Las Americas
Oct 18
SDQ12:45 pmSanto Domingo Las Americas
10h 35m
1 stop
SCL12:20 amSantiago Arturo Merino Benitez
$657
Avianca
Dec 29
SCL7:25 amSantiago Arturo Merino Benitez
10h 25m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
Jan 11
SDQ12:45 pmSanto Domingo Las Americas
15h 45m
1 stop
SCL5:30 amSantiago Arturo Merino Benitez
$668
Avianca
Dec 13
SCL7:25 amSantiago Arturo Merino Benitez
10h 25m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
Jan 5
SDQ12:20 pmSanto Domingo Las Americas
11h 10m
1 stop
SCL12:30 amSantiago Arturo Merino Benitez
$684

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Fri 12/4

3:48 am-2:08 am

1 stop23h 20m

Santo Domingo Las Americas

Thu 12/10

8:55 am-8:11 pm

1 stop10h 16m

$574

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 9/2

12:06 am-1:13 pm

1 stop13h 07m

Santo Domingo Las Americas

Thu 9/10

8:47 am-12:22 am

1 stop14h 35m

$574

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 11/3

1:02 am-11:45 am

1 stop11h 43m

Santo Domingo Las Americas

Wed 11/4

7:06 pm-5:46 am

1 stop9h 40m

$574

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 9/22

3:14 am-4:15 pm

1 stop14h 01m

Santo Domingo Las Americas

Fri 9/25

8:47 am-3:56 am

1 stop18h 09m

$574

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sat 12/19

9:25 am-9:40 pm

1 stop13h 15m

Santo Domingo Las Americas

Sun 1/10

3:55 pm-4:55 am

1 stop12h 00m

$626

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 10/12

1:30 am-11:50 am

1 stop11h 20m

Santo Domingo Las Americas

Sun 10/18

6:50 pm-5:45 am

1 stop9h 55m

$657

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 10/13

7:40 am-5:55 pm

1 stop11h 15m

Santo Domingo Las Americas

Sun 10/18

12:45 pm-12:20 am

1 stop10h 35m

$657
Quickest round-trip

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 8/17

6:40 am-5:55 pm

1 stop11h 15m

Santo Domingo Las Americas

Mon 8/24

6:50 pm-4:45 am

1 stop9h 55m

$657

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 9/3

1:11 am-11:57 pm

1 stop22h 46m

Santo Domingo Las Americas

Thu 9/24

9:00 pm-5:08 am

1 stop31h 08m

$670

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 8/13

11:05 pm-11:57 pm

2 stops24h 52m

Santo Domingo Las Americas

Sun 8/16

5:55 pm-9:55 pm

3 stops28h 00m

$697

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Santiago to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Santo Domingo?

Prices are currently low for flights on this route.

Typical prices usually range from $587 to $699.
The lowest price recently found on this route was $574.

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until November to fly from Santiago, when ticket prices are also cheap, with an average price of $543.

How far in advance should I book a flight from Santiago to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $625 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Santiago for as low as $588 on momondo.

Can stopping save me money on Santiago to Santo Domingo flights?

No. A direct flight is the cheapest option for a flight between Santiago to Santo Domingo.

How have Santiago to Santo Domingo flight prices changed over time?

As of July 2026, prices for Santiago to Santo Domingo flights are approximately 0% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Santo Domingo (SCL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Santo Domingo

Fastest flight time

11h 34m

Direct flights

None
The fastest flight from Santiago to Santo Domingo takes 11h 34m
There are no direct flights from Santiago to Santo Domingo. There are no popular flight routes from Santiago to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Santiago to Santo Domingo

  • How far is Santiago Arturo Merino Benitez to Santo Domingo Las Americas by plane?

    The distance between Santiago Arturo Merino Benitez and Santo Domingo Las Americas is about 3586.0 mi. 11h 34m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to Santo Domingo?

Best airlines flying from Santiago to Santo Domingo

Compare and see reviews for airlines that fly from Santiago to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $517Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
AviancaPriceFrom $536Free CancellationRating
6.5
2,523 reviews
Search Avianca flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Santiago.

Can I find flights from Santiago to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Santiago.

I’m not ready to book a flight from Santiago to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Santo Domingo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 8/29
Sat 9/5
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the Dominican Republic