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Cheap flights from Santiago to Santo Domingo from $298

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Santo Domingo departing on 3/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santiago to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
5:21 am - 4:14 pm
SCL
-
SDQ
11h 53m
1 stop
Copa Airlines Logo
11:56 am - 11:49 pm
SDQ
-
SCL
10h 53m
1 stop
$546Copa Airlines
Mon, Mar 9 - Thu, Mar 19
Copa Airlines Logo
3:32 am - 1:11 pm
SCL
-
SDQ
10h 39m
1 stop
Copa Airlines Logo
11:56 am - 12:34 am
SDQ
-
SCL
11h 38m
1 stop
$566Copa Airlines
Sat, Mar 14 - Sun, Mar 22
Avianca Logo
6:40 am - 11:50 am
SCL
-
SDQ
29h 10m
1 stop
Avianca Logo
6:50 pm - 2:15 pm
SDQ
-
SCL
19h 25m
1 stop
$574Avianca
Fri, May 1 - Fri, May 8
Copa Airlines Logo
11:25 am - 2:20 am
SCL
-
SDQ
14h 55m
1 stop
Copa Airlines Logo
12:40 pm - 3:00 am
SDQ
-
SCL
14h 20m
1 stop
$582Copa Airlines
Mon, Apr 27 - Mon, Jun 15
Copa Airlines Logo
1:49 am - 11:31 am
SCL
-
SDQ
10h 42m
1 stop
Copa Airlines Logo
8:43 am - 2:20 am
SDQ
-
SCL
17h 37m
1 stop
$586Copa Airlines
Sat, Mar 28 - Sun, Apr 5
Multiple Airlines Logo
8:20 pm - 8:45 am
SCL
-
SDQ
12h 25m
1 stop
Multiple Airlines Logo
9:00 pm - 1:35 pm
SDQ
-
SCL
16h 35m
1 stop
$597Multiple Airlines
Tue, Jun 23 - Tue, Jul 7
Copa Airlines Logo
11:25 am - 10:47 pm
SCL
-
SDQ
11h 22m
1 stop
Copa Airlines Logo
6:02 am - 7:23 pm
SDQ
-
SCL
13h 21m
1 stop
$602Copa Airlines
Tue, Apr 7 - Tue, Apr 14
Avianca Logo
1:35 am - 4:50 pm
SCL
-
SDQ
16h 15m
1 stop
Avianca Logo
5:45 pm - 5:30 am
SDQ
-
SCL
10h 45m
1 stop
$603Avianca
Wed, Mar 11 - Sun, Mar 15
Copa Airlines Logo
4:14 am - 4:15 pm
SCL
-
SDQ
12h 01m
1 stop
Copa Airlines Logo
8:48 am - 2:20 am
SDQ
-
SCL
17h 32m
1 stop
$619Copa Airlines
Mon, Jul 27 - Mon, Aug 3
Multiple Airlines Logo
8:20 pm - 8:45 am
SCL
-
SDQ
12h 25m
1 stop
Multiple Airlines Logo
9:00 pm - 7:00 pm
SDQ
-
SCL
22h 00m
2 stops
$634Multiple Airlines
Tue, Jun 23 - Tue, Jul 7

Avianca flights from Santiago to Santo Domingo

Our best Avianca deals on Santiago to Santo Domingo flight tickets
Avianca
May 1
SCL6:40 amSantiago Arturo Merino Benitez
29h 10m
1 stop
SDQ11:50 amSanto Domingo Las Americas
May 8
SDQ6:50 pmSanto Domingo Las Americas
19h 25m
1 stop
SCL2:15 pmSantiago Arturo Merino Benitez
$574
Avianca
Mar 11
SCL1:35 amSantiago Arturo Merino Benitez
16h 15m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
Mar 15
SDQ5:45 pmSanto Domingo Las Americas
10h 45m
1 stop
SCL5:30 amSantiago Arturo Merino Benitez
$603
Avianca
Feb 23
SCL7:25 amSantiago Arturo Merino Benitez
10h 25m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
Mar 2
SDQ5:45 pmSanto Domingo Las Americas
10h 45m
1 stop
SCL5:30 amSantiago Arturo Merino Benitez
$957

Copa Airlines flights from Santiago to Santo Domingo

Our best Copa Airlines deals on Santiago to Santo Domingo flight tickets
Copa Airlines
Mar 9
SCL5:21 amSantiago Arturo Merino Benitez
11h 53m
1 stop
SDQ4:14 pmSanto Domingo Las Americas
Mar 19
SDQ11:56 amSanto Domingo Las Americas
10h 53m
1 stop
SCL11:49 pmSantiago Arturo Merino Benitez
$546
Copa Airlines
Mar 14
SCL3:32 amSantiago Arturo Merino Benitez
10h 39m
1 stop
SDQ1:11 pmSanto Domingo Las Americas
Mar 22
SDQ11:56 amSanto Domingo Las Americas
11h 38m
1 stop
SCL12:34 amSantiago Arturo Merino Benitez
$566
Copa Airlines
Apr 27
SCL11:25 amSantiago Arturo Merino Benitez
14h 55m
1 stop
SDQ2:20 amSanto Domingo Las Americas
Jun 15
SDQ12:40 pmSanto Domingo Las Americas
14h 20m
1 stop
SCL3:00 amSantiago Arturo Merino Benitez
$582

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 3/9

5:21 am-4:14 pm

1 stop11h 53m

Santo Domingo Las Americas

Thu 3/19

11:56 am-11:49 pm

1 stop10h 53m

$546

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sat 3/14

3:32 am-1:11 pm

1 stop10h 39m

Santo Domingo Las Americas

Sun 3/22

11:56 am-12:34 am

1 stop11h 38m

$566

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Fri 5/1

6:40 am-11:50 am

1 stop29h 10m

Santo Domingo Las Americas

Fri 5/8

6:50 pm-2:15 pm

1 stop19h 25m

$574

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 4/27

11:25 am-2:20 am

1 stop14h 55m

Santo Domingo Las Americas

Mon 6/15

12:40 pm-3:00 am

1 stop14h 20m

$582

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sat 3/28

1:49 am-11:31 am

1 stop10h 42m

Santo Domingo Las Americas

Sun 4/5

8:43 am-2:20 am

1 stop17h 37m

$586

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 6/23

8:20 pm-8:45 am

1 stop12h 25m

Santo Domingo Las Americas

Tue 7/7

9:00 pm-1:35 pm

1 stop16h 35m

$597

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 4/7

11:25 am-10:47 pm

1 stop11h 22m

Santo Domingo Las Americas

Tue 4/14

6:02 am-7:23 pm

1 stop13h 21m

$602

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 3/11

1:35 am-4:50 pm

1 stop16h 15m

Santo Domingo Las Americas

Sun 3/15

5:45 pm-5:30 am

1 stop10h 45m

$603

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 7/27

4:14 am-4:15 pm

1 stop12h 01m

Santo Domingo Las Americas

Mon 8/3

8:48 am-2:20 am

1 stop17h 32m

$619

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 6/23

8:20 pm-8:45 am

1 stop12h 25m

Santo Domingo Las Americas

Tue 7/7

9:00 pm-7:00 pm

2 stops22h 00m

$634

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Santiago to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in August, then you should wait until September to fly from Santiago, when ticket prices are also cheap, with an average price of $535.

What is the cheapest Santiago Arturo Merino Benitez to Santo Domingo Las Americas flight route?

Fly from Santiago Arturo Merino Benitez to Santo Domingo Las Americas for the best Santiago Arturo Merino Benitez - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $576 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Santiago for as low as $536 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Santo Domingo Las Americas flights?

There is only 1 cabin class available to choose from on Santiago Arturo Merino Benitez to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Santo Domingo flights?

No. A direct flight is the cheapest option for a flight between Santiago to Santo Domingo.

How have Santiago to Santo Domingo flight prices changed over time?

As of February 2026, prices for Santiago to Santo Domingo flights are approximately 44% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Santo Domingo (SCL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Santo Domingo

Fastest flight time

11h 22m

Direct flights

None
The fastest flight from Santiago to Santo Domingo takes 11h 22m
There are no direct flights from Santiago to Santo Domingo. There are no popular flight routes from Santiago to Santo Domingo.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Santo Domingo Las Americas by plane?

    The distance between Santiago Arturo Merino Benitez and Santo Domingo Las Americas is about 3586.0 mi. 11h 22m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to Santo Domingo?

Best airlines flying from Santiago to Santo Domingo

Compare and see reviews for airlines that fly from Santiago to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $495Free CancellationRating
7.5
1,559 reviews
Search Copa Airlines flights
AviancaPriceFrom $502Free CancellationRating
6.5
2,495 reviews
Search Avianca flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Santiago.

Can I find flights from Santiago to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Santiago.

I’m not ready to book a flight from Santiago to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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