Cheap flights from Santiago to Santo Domingo from $327

1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Santiago to Santo Domingo

Cheap round-trip flights

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Avianca Logo
7:30 am - 5:50 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 20m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 5:45 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
16h 00m1 stop Bogotá El Dorado
$572Avianca
Wed, Dec 2 - Sun, Dec 6
Avianca Logo
7:30 am - 5:50 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 20m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 5:45 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
16h 00m1 stop Bogotá El Dorado
$635Avianca
Wed, Dec 9 - Wed, Dec 16
Avianca Logo
2:10 am - 11:50 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
10h 40m1 stop Bogotá El Dorado
Avianca Logo
6:45 pm - 3:10 pmSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
19h 25m1 stop Bogotá El Dorado
$674Avianca
Mon, Jan 18 - Tue, Jan 19
Avianca Logo
4:15 pm - 11:50 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
20h 35m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 1:05 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
11h 20m1 stop Bogotá El Dorado
$705Avianca
Mon, Dec 21 - Mon, Jan 25
Copa Airlines Logo
1:07 am - 10:58 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
22h 51m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:52 am - 5:57 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
20h 05m1 stop Panama City Tocumen Intl
$730Copa Airlines
Wed, Dec 9 - Thu, Jan 7
Copa Airlines Logo
12:15 pm - 1:10 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
25h 55m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:42 pm - 12:28 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
10h 46m1 stop Panama City Tocumen Intl
$730Copa Airlines
Fri, Nov 27 - Fri, Jan 8
Copa Airlines Logo
1:31 am - 1:14 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
12h 43m1 stop Panama City Tocumen Intl
Copa Airlines Logo
5:50 am - 3:46 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
20h 56m1 stop Panama City Tocumen Intl
$730Copa Airlines
Tue, Dec 8 - Tue, Jan 12
Multiple Airlines Logo
1:11 am - 1:37 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
12h 26m1 stop Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
7:40 am - 12:11 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
16h 31m2 stops Bogotá El Dorado Medellín Jose Maria Cordova Intl
$769Multiple Airlines
Mon, Apr 5 - Sun, Apr 25
Multiple Airlines Logo
2:13 am - 1:49 pmSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
12h 36m1 stop Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
2:01 pm - 3:56 amSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
13h 55m2 stops Medellín Jose Maria Cordova Intl Lima J Chavez Intl
$778Multiple Airlines
Mon, Mar 15 - Tue, Apr 6
Multiple Airlines Logo
8:35 pm - 7:10 amSCL  Santiago Arturo Merino Benitez-SDQ Santo Domingo Las Americas
11h 35m1 stop Lima J Chavez Intl
Multiple Airlines Logo
10:21 pm - 9:33 pmSDQ  Santo Domingo Las Americas-SCL Santiago Arturo Merino Benitez
22h 12m2 stops Lima J Chavez Intl Trujillo
$814Multiple Airlines
Wed, Dec 2 - Sun, Dec 6

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Avianca flights from Santiago to Santo Domingo

Our best Avianca deals on Santiago to Santo Domingo flight tickets
Avianca
Nov 13
SCL8:55 amSantiago Arturo Merino Benitez
27h 55m
1 stop
SDQ11:50 amSanto Domingo Las Americas
Nov 15
SDQ6:45 pmSanto Domingo Las Americas
29h 20m
1 stop
SCL1:05 amSantiago Arturo Merino Benitez
$557
Avianca
Dec 2
SCL7:30 amSantiago Arturo Merino Benitez
11h 20m
1 stop
SDQ5:50 pmSanto Domingo Las Americas
Dec 6
SDQ12:45 pmSanto Domingo Las Americas
16h 00m
1 stop
SCL5:45 amSantiago Arturo Merino Benitez
$572
Avianca
Dec 9
SCL7:30 amSantiago Arturo Merino Benitez
11h 20m
1 stop
SDQ5:50 pmSanto Domingo Las Americas
Dec 16
SDQ12:45 pmSanto Domingo Las Americas
16h 00m
1 stop
SCL5:45 amSantiago Arturo Merino Benitez
$635

Copa Airlines flights from Santiago to Santo Domingo

Our best Copa Airlines deals on Santiago to Santo Domingo flight tickets
Copa Airlines
Dec 8
SCL1:07 amSantiago Arturo Merino Benitez
11h 35m
1 stop
SDQ11:42 amSanto Domingo Las Americas
Jan 12
SDQ8:52 amSanto Domingo Las Americas
17h 54m
1 stop
SCL3:46 amSantiago Arturo Merino Benitez
$730
Copa Airlines
Dec 18
SCL1:31 amSantiago Arturo Merino Benitez
25h 37m
1 stop
SDQ2:08 amSanto Domingo Las Americas
Jan 10
SDQ8:52 amSanto Domingo Las Americas
13h 48m
1 stop
SCL11:40 pmSantiago Arturo Merino Benitez
$753
Copa Airlines
Nov 19
SCL12:15 pmSantiago Arturo Merino Benitez
11h 43m
1 stop
SDQ10:58 pmSanto Domingo Las Americas
Nov 26
SDQ12:45 pmSanto Domingo Las Americas
9h 51m
1 stop
SCL11:36 pmSantiago Arturo Merino Benitez
$761

momondo Fare Finder

 
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Wed 12/2

7:30 am-5:50 pm

1 stop11h 20m

Santo Domingo Las Americas

Sun 12/6

12:45 pm-5:45 am

1 stop16h 00m

$572

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Wed 12/9

7:30 am-5:50 pm

1 stop11h 20m

Santo Domingo Las Americas

Wed 12/16

12:45 pm-5:45 am

1 stop16h 00m

$635

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Mon 1/18

2:10 am-11:50 am

1 stop10h 40m

Santo Domingo Las Americas

Tue 1/19

6:45 pm-3:10 pm

1 stop19h 25m

$674

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Mon 12/21

4:15 pm-11:50 am

1 stop20h 35m

Santo Domingo Las Americas

Mon 1/25

12:45 pm-1:05 am

1 stop11h 20m

$705

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Wed 12/9

1:07 am-10:58 pm

1 stop22h 51m

Santo Domingo Las Americas

Thu 1/7

8:52 am-5:57 am

1 stop20h 05m

$730

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Fri 11/27

12:15 pm-1:10 pm

1 stop25h 55m

Santo Domingo Las Americas

Fri 1/8

12:42 pm-12:28 am

1 stop10h 46m

$730

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Tue 12/8

1:31 am-1:14 pm

1 stop12h 43m

Santo Domingo Las Americas

Tue 1/12

5:50 am-3:46 am

1 stop20h 56m

$730

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Mon 4/5

1:11 am-1:37 pm

1 stop12h 26m

Santo Domingo Las Americas

Sun 4/25

7:40 am-12:11 am

2 stops16h 31m

$769
Quickest round-trip

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Mon 3/15

2:13 am-1:49 pm

1 stop12h 36m

Santo Domingo Las Americas

Tue 4/6

2:01 pm-3:56 am

2 stops13h 55m

$778

SantiagoSanto Domingo

SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas

SCLSDQ

Santiago Arturo Merino Benitez

Wed 12/2

8:35 pm-7:10 am

1 stop11h 35m

Santo Domingo Las Americas

Sun 12/6

10:21 pm-9:33 pm

2 stops22h 12m

$814

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Santiago to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Santo Domingo?

Prices are currently typical for flights on this route.

Typical prices usually range from $537 to $619.
The lowest price recently found on this route was $572.

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in March, then you should wait until November to fly from Santiago, when ticket prices are also cheap, with an average price of $573.

How far in advance should I book a flight from Santiago to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $642 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Santiago for as low as $591 on momondo.

How have Santiago to Santo Domingo flight prices changed over time?

As of November 2026, prices for Santiago to Santo Domingo flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Santo Domingo (SCL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Santo Domingo

Best Price Found

$327

Fastest flight time

25h 55m

Direct flights

None
The best one-way flight to Santo Domingo from Santiago in the past 72 hours is $327. The best round-trip flight deal from Santiago to Santo Domingo found on momondo in the last 72 hours is $572.
The fastest flight from Santiago to Santo Domingo takes 25h 55m
There are no direct flights from Santiago to Santo Domingo. There are no popular flight routes from Santiago to Santo Domingo.

Frequently asked questions about flying from Santiago to Santo Domingo

  • How far is Santiago Arturo Merino Benitez to Santo Domingo Las Americas by plane?

    The distance between Santiago Arturo Merino Benitez and Santo Domingo Las Americas is about 3586.0 mi. 25h 55m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santiago to Santo Domingo?

Best airlines flying from Santiago to Santo Domingo

Compare and see reviews for airlines that fly from Santiago to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $536Free CancellationRating
6.5
2,546 reviews
Search Avianca flights
Copa AirlinesPriceFrom $545Free CancellationRating
7.6
1,554 reviews
Search Copa Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Santiago.

Can I find flights from Santiago to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Santiago.

I’m not ready to book a flight from Santiago to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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