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Cheap flights from Santiago to Santo Domingo from $207

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Santo Domingo departing on 11/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santiago to Santo Domingo

Cheap round-trip flights

Logo
6:00 am - 4:45 pmSCL-SDQ
11h 45m1 stop
Logo
2:05 pm - 3:35 amSDQ-SCL
12h 30m1 stop
$428
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Mon, Nov 3 - Thu, Nov 20
Logo
6:00 am - 4:45 pmSCL-SDQ
11h 45m1 stop
Logo
3:25 pm - 4:55 amSDQ-SCL
12h 30m1 stop
$436
Find Deal
Wed, Dec 3 - Sun, Dec 7
Avianca Logo
1:35 am - 4:50 pmSCL-SDQ
16h 15m1 stop
Avianca Logo
12:20 pm - 5:30 amSDQ-SCL
16h 10m1 stop
$535Avianca
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Wed, Oct 29 - Thu, Nov 6
Copa Airlines Logo
3:35 am - 10:25 pmSCL-SDQ
19h 50m1 stop
Copa Airlines Logo
11:57 am - 3:42 amSDQ-SCL
14h 45m1 stop
$536Copa Airlines
Find Deal
Sun, Oct 5 - Thu, Oct 23
Copa Airlines Logo
3:35 am - 4:15 pmSCL-SDQ
13h 40m1 stop
Copa Airlines Logo
5:00 am - 10:41 pmSDQ-SCL
16h 41m1 stop
$537Copa Airlines
Find Deal
Sun, Oct 26 - Sun, Nov 2
Copa Airlines Logo
12:20 pm - 10:25 pmSCL-SDQ
11h 05m1 stop
Copa Airlines Logo
8:55 am - 6:01 amSDQ-SCL
20h 06m1 stop
$539Copa Airlines
Find Deal
Mon, Nov 24 - Wed, Dec 3
Copa Airlines Logo
1:13 am - 10:58 amSCL-SDQ
10h 45m1 stop
Copa Airlines Logo
8:58 am - 3:42 amSDQ-SCL
17h 44m1 stop
$556Copa Airlines
Find Deal
Sat, Sep 27 - Sun, Oct 5
Avianca Logo
4:25 pm - 4:50 pmSCL-SDQ
25h 25m1 stop
Avianca Logo
5:45 pm - 4:05 amSDQ-SCL
33h 20m2 stops
$1,157Avianca
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Tue, Jan 13 - Tue, Feb 17
United Airlines Logo
9:45 pm - 10:46 pmSCL-SDQ
26h 01m2 stops
United Airlines Logo
6:00 am - 8:50 amSDQ-SCL
25h 50m2 stops
$1,392United Airlines
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Mon, Oct 27 - Tue, Nov 18
United Airlines Logo
9:45 pm - 10:46 pmSCL-SDQ
26h 01m2 stops
United Airlines Logo
6:00 am - 8:50 amSDQ-SCL
25h 50m2 stops
$1,393United Airlines
Find Deal
Mon, Oct 27 - Tue, Nov 18

Copa Airlines flights from Santiago to Santo Domingo

Our best Copa Airlines deals on Santiago to Santo Domingo flight tickets
Copa Airlines
Oct 5
SCL3:35 amSantiago Arturo Merino Benitez
19h 50m
1 stop
SDQ10:25 pmSanto Domingo Las Americas
Oct 23
SDQ11:57 amSanto Domingo Las Americas
14h 45m
1 stop
SCL3:42 amSantiago Arturo Merino Benitez
$536
Find similar
Copa Airlines
Oct 26
SCL3:35 amSantiago Arturo Merino Benitez
13h 40m
1 stop
SDQ4:15 pmSanto Domingo Las Americas
Nov 2
SDQ5:00 amSanto Domingo Las Americas
16h 41m
1 stop
SCL10:41 pmSantiago Arturo Merino Benitez
$537
Find similar
Copa Airlines
Nov 24
SCL12:20 pmSantiago Arturo Merino Benitez
11h 05m
1 stop
SDQ10:25 pmSanto Domingo Las Americas
Dec 3
SDQ8:55 amSanto Domingo Las Americas
20h 06m
1 stop
SCL6:01 amSantiago Arturo Merino Benitez
$539
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Avianca flights from Santiago to Santo Domingo

Our best Avianca deals on Santiago to Santo Domingo flight tickets
Avianca
Sep 21
SCL3:30 pmSantiago Arturo Merino Benitez
20h 20m
1 stop
SDQ10:50 amSanto Domingo Las Americas
Sep 26
SDQ6:10 pmSanto Domingo Las Americas
19h 15m
1 stop
SCL2:25 pmSantiago Arturo Merino Benitez
$533
Find similar
Avianca
Oct 29
SCL1:35 amSantiago Arturo Merino Benitez
16h 15m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
Nov 6
SDQ12:20 pmSanto Domingo Las Americas
16h 10m
1 stop
SCL5:30 amSantiago Arturo Merino Benitez
$535
Find similar
Avianca
Jan 13
SCL4:25 pmSantiago Arturo Merino Benitez
25h 25m
1 stop
SDQ4:50 pmSanto Domingo Las Americas
Feb 17
SDQ5:45 pmSanto Domingo Las Americas
33h 20m
2 stops
SCL4:05 amSantiago Arturo Merino Benitez
$1,157
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momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 11/3

6:00 am-4:45 pm

1 stop11h 45m

Santo Domingo Las Americas

Thu 11/20

2:05 pm-3:35 am

1 stop12h 30m

$428

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 12/3

6:00 am-4:45 pm

1 stop11h 45m

Santo Domingo Las Americas

Sun 12/7

3:25 pm-4:55 am

1 stop12h 30m

$436

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 10/29

1:35 am-4:50 pm

1 stop16h 15m

Santo Domingo Las Americas

Thu 11/6

12:20 pm-5:30 am

1 stop16h 10m

$535

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sun 10/5

3:35 am-10:25 pm

1 stop19h 50m

Santo Domingo Las Americas

Thu 10/23

11:57 am-3:42 am

1 stop14h 45m

$536

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sun 10/26

3:35 am-4:15 pm

1 stop13h 40m

Santo Domingo Las Americas

Sun 11/2

5:00 am-10:41 pm

1 stop16h 41m

$537

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 11/24

12:20 pm-10:25 pm

1 stop11h 05m

Santo Domingo Las Americas

Wed 12/3

8:55 am-6:01 am

1 stop20h 06m

$539

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sat 9/27

1:13 am-10:58 am

1 stop10h 45m

Santo Domingo Las Americas

Sun 10/5

8:58 am-3:42 am

1 stop17h 44m

$556

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Tue 1/13

4:25 pm-4:50 pm

1 stop25h 25m

Santo Domingo Las Americas

Tue 2/17

5:45 pm-4:05 am

2 stops33h 20m

$1,157

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 10/27

9:45 pm-10:46 pm

2 stops26h 01m

Santo Domingo Las Americas

Tue 11/18

6:00 am-8:50 am

2 stops25h 50m

$1,392

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 10/27

9:45 pm-10:46 pm

2 stops26h 01m

Santo Domingo Las Americas

Tue 11/18

6:00 am-8:50 am

2 stops25h 50m

$1,393

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Santiago to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in November, then you should wait until May to fly from Santiago, when ticket prices are also cheap, with an average price of $532.

What is the cheapest Santiago Arturo Merino Benitez to Santo Domingo Las Americas flight route?

Fly from Santiago Arturo Merino Benitez to Santo Domingo Las Americas for the best Santiago Arturo Merino Benitez - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $567 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Santiago for as low as $544 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Santo Domingo Las Americas flights?

There is only 1 cabin class available to choose from on Santiago Arturo Merino Benitez to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santiago to Santo Domingo flight prices changed over time?

As of September 2025, prices for Santiago to Santo Domingo flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Santo Domingo (SCL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Santo Domingo

Direct flights

None
There are no direct flights from Santiago to Santo Domingo. There are no popular flight routes from Santiago to Santo Domingo.
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  • How far is Santiago Arturo Merino Benitez to Santo Domingo Las Americas by plane?

    The distance between Santiago Arturo Merino Benitez and Santo Domingo Las Americas is about 3586.0 mi. 10h 25m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Santo Domingo?

  • What is the most popular airline from Santiago to Santo Domingo?

Best airlines flying from Santiago to Santo Domingo

Compare and see reviews for airlines that fly from Santiago to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $495Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
AviancaPriceFrom $502Free CancellationRating
6.7
2,435 reviews
Search Avianca flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Santiago.

Can I find flights from Santiago to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Santiago.

I’m not ready to book a flight from Santiago to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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