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Cheap flights from Santiago to Santo Domingo from $213

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Santo Domingo departing on 9/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santiago to Santo Domingo

Cheap round-trip flights

Logo
4:35 am - 3:25 pmSCL-SDQ
11h 50m1 stop
Logo
2:25 pm - 3:35 amSDQ-SCL
12h 10m1 stop
$445
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Wed, Sep 10 - Tue, Sep 16
Logo
1:35 am - 9:15 amSCL-SDQ
32h 40m2 stops
Logo
9:30 pm - 2:45 pmSDQ-SCL
16h 15m1 stop
$462
Find Deal
Sat, Sep 20 - Sun, Sep 28
Logo
4:35 am - 4:10 pmSCL-SDQ
12h 35m1 stop
Logo
9:30 pm - 10:15 pmSDQ-SCL
23h 45m1 stop
$465
Find Deal
Mon, Sep 22 - Sun, Sep 28
Avianca Logo
6:10 am - 5:15 pmSCL-SDQ
11h 05m1 stop
Avianca Logo
11:45 am - 4:15 amSDQ-SCL
16h 30m1 stop
$533Avianca
Find Deal
Sat, Aug 16 - Mon, Aug 18
Copa Airlines Logo
12:24 am - 10:58 amSCL-SDQ
10h 34m1 stop
Copa Airlines Logo
11:57 am - 12:04 amSDQ-SCL
11h 07m1 stop
$536Copa Airlines
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Thu, Aug 21 - Sat, Oct 25
Copa Airlines Logo
2:26 am - 6:12 pmSCL-SDQ
15h 46m1 stop
Copa Airlines Logo
11:54 am - 2:46 amSDQ-SCL
14h 52m1 stop
$551Copa Airlines
Find Deal
Fri, Aug 15 - Mon, Aug 18
Copa Airlines Logo
12:13 am - 10:58 amSCL-SDQ
10h 45m1 stop
Copa Airlines Logo
2:07 pm - 2:46 amSDQ-SCL
12h 39m1 stop
$556Copa Airlines
Find Deal
Sat, Aug 16 - Sun, Aug 24
Avianca Logo
6:55 am - 5:20 pmSCL-SDQ
11h 25m1 stop
Avianca Logo
6:15 pm - 5:25 amSDQ-SCL
10h 10m1 stop
$586Avianca
Find Deal
Thu, Jan 15 - Thu, Jan 22
Avianca Logo
2:30 pm - 5:15 pmSCL-SDQ
26h 45m1 stop
Avianca Logo
6:10 pm - 1:25 pmSDQ-SCL
19h 15m1 stop
$587Avianca
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Wed, Aug 13 - Fri, Aug 15
Copa Airlines Logo
12:13 am - 10:58 amSCL-SDQ
10h 45m1 stop
Copa Airlines Logo
11:57 am - 3:42 amSDQ-SCL
14h 45m1 stop
$600Copa Airlines
Find Deal
Thu, Aug 21 - Sat, Oct 25

Avianca flights from Santiago to Santo Domingo

Our best Avianca deals on Santiago to Santo Domingo flight tickets
Avianca
Aug 16
SCL6:10 amSantiago Arturo Merino Benitez
11h 05m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
Aug 18
SDQ11:45 amSanto Domingo Las Americas
16h 30m
1 stop
SCL4:15 amSantiago Arturo Merino Benitez
$533
Find similar
Avianca
Aug 5
SCL6:10 amSantiago Arturo Merino Benitez
11h 05m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
Aug 7
SDQ11:45 amSanto Domingo Las Americas
10h 45m
1 stop
SCL10:30 pmSantiago Arturo Merino Benitez
$560
Find similar
Avianca
Aug 3
SCL6:10 amSantiago Arturo Merino Benitez
28h 40m
1 stop
SDQ10:50 amSanto Domingo Las Americas
Aug 5
SDQ11:45 amSanto Domingo Las Americas
10h 45m
1 stop
SCL10:30 pmSantiago Arturo Merino Benitez
$585
Find similar

Copa Airlines flights from Santiago to Santo Domingo

Our best Copa Airlines deals on Santiago to Santo Domingo flight tickets
Copa Airlines
Aug 21
SCL12:24 amSantiago Arturo Merino Benitez
10h 34m
1 stop
SDQ10:58 amSanto Domingo Las Americas
Oct 25
SDQ11:57 amSanto Domingo Las Americas
11h 07m
1 stop
SCL12:04 amSantiago Arturo Merino Benitez
$536
Find similar
Copa Airlines
Aug 10
SCL2:26 amSantiago Arturo Merino Benitez
15h 46m
1 stop
SDQ6:12 pmSanto Domingo Las Americas
Aug 22
SDQ11:54 amSanto Domingo Las Americas
10h 50m
1 stop
SCL10:44 pmSantiago Arturo Merino Benitez
$551
Find similar
Copa Airlines
Aug 16
SCL12:13 amSantiago Arturo Merino Benitez
10h 45m
1 stop
SDQ10:58 amSanto Domingo Las Americas
Aug 24
SDQ2:07 pmSanto Domingo Las Americas
12h 39m
1 stop
SCL2:46 amSantiago Arturo Merino Benitez
$556
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 1, 2025.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 9/10

4:35 am-3:25 pm

1 stop11h 50m

Santo Domingo Las Americas

Tue 9/16

2:25 pm-3:35 am

1 stop12h 10m

$445

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sat 9/20

1:35 am-9:15 am

2 stops32h 40m

Santo Domingo Las Americas

Sun 9/28

9:30 pm-2:45 pm

1 stop16h 15m

$462

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Mon 9/22

4:35 am-4:10 pm

1 stop12h 35m

Santo Domingo Las Americas

Sun 9/28

9:30 pm-10:15 pm

1 stop23h 45m

$465

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sat 8/16

6:10 am-5:15 pm

1 stop11h 05m

Santo Domingo Las Americas

Mon 8/18

11:45 am-4:15 am

1 stop16h 30m

$533

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 8/21

12:24 am-10:58 am

1 stop10h 34m

Santo Domingo Las Americas

Sat 10/25

11:57 am-12:04 am

1 stop11h 07m

$536

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Fri 8/15

2:26 am-6:12 pm

1 stop15h 46m

Santo Domingo Las Americas

Mon 8/18

11:54 am-2:46 am

1 stop14h 52m

$551

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Sat 8/16

12:13 am-10:58 am

1 stop10h 45m

Santo Domingo Las Americas

Sun 8/24

2:07 pm-2:46 am

1 stop12h 39m

$556

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 1/15

6:55 am-5:20 pm

1 stop11h 25m

Santo Domingo Las Americas

Thu 1/22

6:15 pm-5:25 am

1 stop10h 10m

$586

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Wed 8/13

2:30 pm-5:15 pm

1 stop26h 45m

Santo Domingo Las Americas

Fri 8/15

6:10 pm-1:25 pm

1 stop19h 15m

$587

SantiagoSanto Domingo

SCL - SDQ

SCLSDQ

Santiago Arturo Merino Benitez

Thu 8/21

12:13 am-10:58 am

1 stop10h 45m

Santo Domingo Las Americas

Sat 10/25

11:57 am-3:42 am

1 stop14h 45m

$600

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Santiago to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until August to fly from Santiago, when ticket prices are also cheap, with an average price of $515.

What is the cheapest Santiago Arturo Merino Benitez to Santo Domingo Las Americas flight route?

Fly from Santiago Arturo Merino Benitez to Santo Domingo Las Americas for the best Santiago Arturo Merino Benitez - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $558 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Santiago for as low as $510 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Santo Domingo Las Americas flights?

There are 1 cabin classes available to choose from on Santiago Arturo Merino Benitez to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santiago to Santo Domingo flights?

No. A direct flight is the cheapest option for a flight between Santiago to Santo Domingo.

How have Santiago to Santo Domingo flight prices changed over time?

As of August 2025, prices for Santiago to Santo Domingo flights are approximately 24% cheaper when compared to flights at the same time last year.

When to book flights from Santiago to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Santo Domingo (SCL to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Santo Domingo

Best Price Found

$213

Fastest flight time

10h 30m

Direct flights

None

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Santiago in the past 72 hours is $213. The best round-trip flight deal from Santiago to Santo Domingo found on momondo in the last 72 hours is $445.
The fastest flight from Santiago to Santo Domingo takes 10h 30m
There are no direct flights from Santiago to Santo Domingo. Popular non-direct route for this connection is Santiago Arturo Merino Benitez Airport - Santo Domingo Las Americas Airport.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)
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  • How far is Santiago Arturo Merino Benitez to Santo Domingo Las Americas by plane?

    The distance between Santiago Arturo Merino Benitez and Santo Domingo Las Americas is about 3586.0 mi. 10h 30m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport refresh daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Santiago to Santo Domingo?

  • What is the most popular airline from Santiago to Santo Domingo?

Best airlines flying from Santiago to Santo Domingo

Compare and see reviews for airlines that fly from Santiago to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $379Free CancellationRating
7.5
1,493 reviews
Search Copa Airlines flights
AviancaPriceFrom $502Free CancellationRating
6.7
2,388 reviews
Search Avianca flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Santiago.

Can I find flights from Santiago to Santo Domingo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santiago to Santo Domingo flights to just show those with flexible booking policies.

How can momondo help me find flights from Santiago to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Santiago.

I’m not ready to book a flight from Santiago to Santo Domingo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santo Domingo from Santiago. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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