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Cheap flights from Santiago to Panama City from $249

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Panama City departing on 6/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Avianca Logo
11:55 pm - 4:30 pmSCL-PTY
17h 35m1 stop
Avianca Logo
3:25 am - 2:25 pmPTY-SCL
9h 00m1 stop
$536Avianca
Find Deal
Fri, Aug 8 - Mon, Sep 29
Copa Airlines Logo
11:29 am - 5:20 pmSCL-PTY
6h 51mnonstop
Copa Airlines Logo
7:11 pm - 2:46 amPTY-SCL
6h 35mnonstop
$540Copa Airlines
Find Deal
Sun, Aug 10 - Sun, Aug 17
Copa Airlines Logo
2:30 am - 7:23 amSCL-PTY
6h 53mnonstop
Copa Airlines Logo
11:44 am - 8:17 pmPTY-SCL
6h 33mnonstop
$555Copa Airlines
Find Deal
Mon, Oct 27 - Fri, Oct 31
Avianca Logo
11:55 pm - 9:10 pmSCL-PTY
22h 15m1 stop
Avianca Logo
10:05 pm - 1:25 pmPTY-SCL
14h 20m1 stop
$559Avianca
Find Deal
Sun, Jul 13 - Sun, Jul 20
Copa Airlines Logo
11:27 am - 5:20 pmSCL-PTY
6h 53mnonstop
Copa Airlines Logo
3:32 pm - 11:08 pmPTY-SCL
6h 36mnonstop
$570Copa Airlines
Find Deal
Mon, Jul 28 - Mon, Aug 4
Avianca Logo
6:10 am - 7:15 pmSCL-PTY
14h 05m2 stops
Avianca Logo
9:55 am - 5:15 amPTY-SCL
17h 20m1 stop
$580Avianca
Find Deal
Fri, Aug 8 - Tue, Sep 30
Avianca Logo
11:55 pm - 2:40 pmSCL-PTY
15h 45m2 stops
Avianca Logo
3:20 am - 1:25 pmPTY-SCL
33h 05m1 stop
$581Avianca
Find Deal
Mon, Aug 18 - Thu, Aug 21
United Airlines Logo
9:45 pm - 2:32 pmSCL-PTY
18h 47m2 stops
United Airlines Logo
10:25 am - 7:50 amPTY-SCL
19h 25m2 stops
$1,650United Airlines
Find Deal
Tue, Oct 28 - Fri, Oct 31
United Airlines Logo
9:45 pm - 2:32 pmSCL-PTY
18h 47m2 stops
United Airlines Logo
10:25 am - 7:50 amPTY-SCL
19h 25m2 stops
$1,663United Airlines
Find Deal
Tue, Oct 28 - Fri, Oct 31
Iberia Logo
8:00 pm - 2:31 pmSCL-PTY
68h 31m2 stops
Iberia Logo
1:50 pm - 8:20 amPTY-SCL
64h 30m2 stops
$3,143Iberia
Find Deal
Tue, Sep 30 - Tue, Oct 7

Avianca flights from Santiago to Panama City

Our best Avianca deals on Santiago to Panama City flight tickets
Avianca
Aug 8
SCL11:55 pmSantiago Arturo Merino Benitez
17h 35m
1 stop
PTY4:30 pmPanama City Tocumen Intl
Sep 29
PTY3:25 amPanama City Tocumen Intl
9h 00m
1 stop
SCL2:25 pmSantiago Arturo Merino Benitez
Avianca
Jul 13
SCL11:55 pmSantiago Arturo Merino Benitez
22h 15m
1 stop
PTY9:10 pmPanama City Tocumen Intl
Jul 20
PTY10:05 pmPanama City Tocumen Intl
14h 20m
1 stop
SCL1:25 pmSantiago Arturo Merino Benitez
Avianca
Aug 8
SCL6:10 amSantiago Arturo Merino Benitez
14h 05m
2 stops
PTY7:15 pmPanama City Tocumen Intl
Sep 30
PTY9:55 amPanama City Tocumen Intl
17h 20m
1 stop
SCL5:15 amSantiago Arturo Merino Benitez

Copa Airlines flights from Santiago to Panama City

Our best Copa Airlines deals on Santiago to Panama City flight tickets
Copa Airlines
Aug 10
SCL11:29 amSantiago Arturo Merino Benitez
6h 51m
PTY5:20 pmPanama City Tocumen Intl
Aug 17
PTY7:11 pmPanama City Tocumen Intl
6h 35m
SCL2:46 amSantiago Arturo Merino Benitez
Copa Airlines
Oct 27
SCL2:30 amSantiago Arturo Merino Benitez
6h 53m
PTY7:23 amPanama City Tocumen Intl
Oct 31
PTY11:44 amPanama City Tocumen Intl
6h 33m
SCL8:17 pmSantiago Arturo Merino Benitez
Copa Airlines
Jul 28
SCL11:27 amSantiago Arturo Merino Benitez
6h 53m
PTY5:20 pmPanama City Tocumen Intl
Aug 4
PTY3:32 pmPanama City Tocumen Intl
6h 36m
SCL11:08 pmSantiago Arturo Merino Benitez

See travel insights to Panama City from

How to get the cheapest flight ticket from Santiago to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santiago and Panama City?

What is the cheapest month to fly to Panama City?

In general, August is the cheapest month to fly from Santiago to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $452. If you’re not able to fly to Panama City in August, then October is your next best option. Flight prices from Santiago to Panama City during October average around $471.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Sunday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $545. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $600. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Santiago to Panama City during this time can be as low as $416. Try not to purchase tickets at noon because they tend to be around $596. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Santiago Arturo Merino Benitez to Panama City Tocumen Intl flight route?

Fly from Santiago Arturo Merino Benitez to Panama City Tocumen Intl for the best Santiago Arturo Merino Benitez - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Santiago when booking 19 weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $515 when searching 19 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Santiago for as low as $440 on momondo.

What cabin class options are available on Santiago Arturo Merino Benitez to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Santiago Arturo Merino Benitez to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Santiago to Panama City flight prices changed over time?

As of June 2025, prices for Santiago to Panama City flights are approximately 28% more expensive when compared to flights at the same time last year.

When to book flights from Santiago to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Panama City (SCL to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Panama City

Best Price Found

$249

Fastest flight time

6h 51m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Santiago in the past 72 hours is $249. The best round-trip flight deal from Santiago to Panama City found on momondo in the last 72 hours is $536.
The fastest flight from Santiago to Panama City takes 6h 51m
Direct flights go from Santiago to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

  • How far is Santiago Arturo Merino Benitez to Panama City Tocumen Intl by plane?

    There are 2987.0 mi between Santiago Arturo Merino Benitez and Panama City Tocumen Intl. 6h 51m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Santiago Arturo Merino Benitez Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Santiago to Panama City?

  • What is the most popular airline from Santiago to Panama City?


Best airlines flying from Santiago to Panama City

Compare and see reviews for airlines that fly from Santiago to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $302Free CancellationRating
6.7
2,345 reviews
Search Avianca flights
Copa AirlinesPriceFrom $424Free CancellationRating
7.5
1,451 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Santiago to Panama City

    Across 35 Copa Airlines flights from Santiago to Panama City this week, the average price was $591, with the best Copa Airlines deals starting from $424 round-trip. 1,451 users have rated Copa Airlines on momondo, with an average score of 7.5/10.


Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to Panama City with flexible booking policies on momondo?

Flights from Santiago to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Santiago to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Santiago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santiago to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santiago to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.


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1 adult
Fri 6/20
Fri 6/27

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