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Cheap flights from Santiago to Detroit from $312

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago to Detroit departing on 3/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santiago to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:05 pm - 10:37 pm
SCL
-
DTW
26h 32m
3 stops
Multiple Airlines Logo
5:20 am - 2:30 pm
DTW
-
SCL
32h 10m
2 stops
$569Multiple Airlines
Thu, Mar 26 - Thu, Apr 2
Multiple Airlines Logo
9:05 pm - 11:59 pm
SCL
-
DTW
27h 54m
2 stops
Multiple Airlines Logo
5:20 am - 2:30 pm
DTW
-
SCL
32h 10m
2 stops
$577Multiple Airlines
Thu, Mar 26 - Thu, Apr 2
Multiple Airlines Logo
7:15 am - 11:59 pm
SCL
-
DTW
17h 44m
2 stops
Multiple Airlines Logo
4:50 pm - 2:30 pm
DTW
-
SCL
44h 40m
2 stops
$624Multiple Airlines
Tue, Mar 24 - Tue, Mar 31
Multiple Airlines Logo
10:30 am - 9:46 am
SCL
-
DTW
25h 16m
1 stop
Multiple Airlines Logo
4:09 pm - 5:14 am
DTW
-
SCL
36h 05m
2 stops
$628Multiple Airlines
Thu, Feb 26 - Thu, Mar 19
Multiple Airlines Logo
11:25 pm - 11:01 am
SCL
-
DTW
36h 36m
1 stop
Multiple Airlines Logo
10:24 am - 6:30 am
DTW
-
SCL
19h 06m
2 stops
$629Multiple Airlines
Thu, Mar 26 - Thu, Apr 2
Multiple Airlines Logo
11:24 am - 3:12 pm
SCL
-
DTW
28h 48m
2 stops
Multiple Airlines Logo
6:05 am - 5:11 am
DTW
-
SCL
22h 06m
3 stops
$634Multiple Airlines
Tue, Mar 24 - Tue, Mar 31
Multiple Airlines Logo
9:05 pm - 10:37 pm
SCL
-
DTW
26h 32m
3 stops
Multiple Airlines Logo
6:05 am - 5:11 am
DTW
-
SCL
22h 06m
3 stops
$638Multiple Airlines
Tue, Mar 24 - Tue, Mar 31
Multiple Airlines Logo
12:35 pm - 9:39 pm
SCL
-
DTW
35h 04m
2 stops
Multiple Airlines Logo
6:05 am - 10:39 am
DTW
-
SCL
27h 34m
3 stops
$642Multiple Airlines
Thu, Feb 26 - Thu, Mar 19
Multiple Airlines Logo
9:05 pm - 9:54 pm
SCL
-
DTW
26h 49m
3 stops
Multiple Airlines Logo
6:05 am - 10:39 am
DTW
-
SCL
27h 34m
3 stops
$655Multiple Airlines
Thu, Feb 26 - Thu, Mar 19
Multiple Airlines Logo
9:05 pm - 9:39 pm
SCL
-
DTW
26h 34m
2 stops
Multiple Airlines Logo
5:45 am - 10:39 am
DTW
-
SCL
27h 54m
2 stops
$672Multiple Airlines
Thu, Feb 26 - Thu, Mar 19

LATAM Airlines flights from Santiago to Detroit Metropolitan Wayne County Airport

Our best LATAM Airlines deals on Santiago to Detroit Metropolitan Wayne County Airport flight tickets
LATAM Airlines
Jun 8
SCL11:00 pmSantiago Arturo Merino Benitez
22h 43m
1 stop
DTW9:43 pmDetroit Metropolitan Wayne County
Jun 23
DTW2:00 pmDetroit Metropolitan Wayne County
16h 55m
1 stop
SCL6:55 amSantiago Arturo Merino Benitez
$767
LATAM Airlines
Mar 3
SCL12:20 amSantiago Arturo Merino Benitez
19h 18m
2 stops
DTW5:38 pmDetroit Metropolitan Wayne County
Mar 8
DTW6:10 pmDetroit Metropolitan Wayne County
19h 00m
2 stops
SCL2:10 pmSantiago Arturo Merino Benitez
$815
LATAM Airlines
Mar 24
SCL11:25 pmSantiago Arturo Merino Benitez
16h 47m
1 stop
DTW3:12 pmDetroit Metropolitan Wayne County
Mar 31
DTW12:35 pmDetroit Metropolitan Wayne County
18h 40m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
$821

Delta flights from Santiago to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Santiago to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Mar 10
SCL6:30 pmSantiago Arturo Merino Benitez
21h 23m
2 stops
DTW2:53 pmDetroit Metropolitan Wayne County
May 26
DTW12:15 pmDetroit Metropolitan Wayne County
17h 45m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
$806
Delta
Mar 10
SCL11:25 pmSantiago Arturo Merino Benitez
21h 36m
2 stops
DTW8:01 pmDetroit Metropolitan Wayne County
May 26
DTW10:30 amDetroit Metropolitan Wayne County
20h 45m
1 stop
SCL7:15 amSantiago Arturo Merino Benitez
$849
Delta
May 14
SCL7:45 amSantiago Arturo Merino Benitez
17h 13m
2 stops
DTW12:58 amDetroit Metropolitan Wayne County
Jul 20
DTW6:30 amDetroit Metropolitan Wayne County
23h 30m
2 stops
SCL6:00 amSantiago Arturo Merino Benitez
$867

momondo Fare Finder

 
Customize your flight search to find flights from Santiago to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Santiago to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Thu 3/26

9:05 pm-10:37 pm

3 stops26h 32m

Detroit Metropolitan Wayne County

Thu 4/2

5:20 am-2:30 pm

2 stops32h 10m

$569

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Thu 3/26

9:05 pm-11:59 pm

2 stops27h 54m

Detroit Metropolitan Wayne County

Thu 4/2

5:20 am-2:30 pm

2 stops32h 10m

$577

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Tue 3/24

7:15 am-11:59 pm

2 stops17h 44m

Detroit Metropolitan Wayne County

Tue 3/31

4:50 pm-2:30 pm

2 stops44h 40m

$624

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Thu 2/26

10:30 am-9:46 am

1 stop25h 16m

Detroit Metropolitan Wayne County

Thu 3/19

4:09 pm-5:14 am

2 stops36h 05m

$628

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Thu 3/26

11:25 pm-11:01 am

1 stop36h 36m

Detroit Metropolitan Wayne County

Thu 4/2

10:24 am-6:30 am

2 stops19h 06m

$629

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Tue 3/24

11:24 am-3:12 pm

2 stops28h 48m

Detroit Metropolitan Wayne County

Tue 3/31

6:05 am-5:11 am

3 stops22h 06m

$634

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Tue 3/24

9:05 pm-10:37 pm

3 stops26h 32m

Detroit Metropolitan Wayne County

Tue 3/31

6:05 am-5:11 am

3 stops22h 06m

$638

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Thu 2/26

12:35 pm-9:39 pm

2 stops35h 04m

Detroit Metropolitan Wayne County

Thu 3/19

6:05 am-10:39 am

3 stops27h 34m

$642

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Thu 2/26

9:05 pm-9:54 pm

3 stops26h 49m

Detroit Metropolitan Wayne County

Thu 3/19

6:05 am-10:39 am

3 stops27h 34m

$655

SantiagoDetroit

SCL - DTW

SCLDTW

Santiago Arturo Merino Benitez

Thu 2/26

9:05 pm-9:39 pm

2 stops26h 34m

Detroit Metropolitan Wayne County

Thu 3/19

5:45 am-10:39 am

2 stops27h 54m

$672

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Santiago to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santiago Arturo Merino Benitez to Detroit Metropolitan Wayne County?

LATAM Airlines is the most popular carrier operating from Santiago Arturo Merino Benitez to Detroit Metropolitan Wayne County

When to book flights from Santiago to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago to Detroit Metropolitan Wayne County Airport (SCL to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago to Detroit Metropolitan Wayne County Airport

Fastest flight time

16h 11m

Direct flights

None
The fastest flight from Santiago to Detroit Metropolitan Wayne County Airport takes 16h 11m
There are no direct flights from Santiago to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Santiago to Detroit Metropolitan Wayne County Airport.
Search flight deals

  • How far is Santiago Arturo Merino Benitez to Detroit Metropolitan Wayne County by plane?

    Detroit Metropolitan Wayne County is 5286.2 mi away from Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 16h 11m.

  • When did momondo last update prices for flights from Santiago Arturo Merino Benitez Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Santiago Arturo Merino Benitez Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How old do you have to be to fly from Santiago Arturo Merino Benitez Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santiago Arturo Merino Benitez Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents you'll need for your trip to Detroit Metropolitan Wayne County Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Detroit Metropolitan Wayne County Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Dearborn
Troy
Romulus
Southfield
Monroe
Novi
Livonia
Port Clinton
Roseville
Port Huron
Sterling Heights
Brighton
Ypsilanti
Dundee
Pontiac
Plymouth
Southgate

Why use momondo?

Why should I use momondo to find a flight deal from Santiago to Detroit?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago to Detroit. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago to Detroit with flexible booking policies on momondo?

momondo does allow users to show only those flights to Detroit from Santiago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santiago to Detroit?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Detroit from Santiago.

I’m not ready to book a flight from Santiago to Detroit right now. Can momondo alert me if prices change?

Price alerts on flights to Detroit from Santiago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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