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Cheap flights from Santa Cruz de la Sierra to Madrid from $595

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Madrid departing on 2/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Santa Cruz de la Sierra to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
Iberia Logo
9:15 pm - 1:55 pm
VVI
-
MAD
10h 40mnonstop
Iberia Logo
9:00 pm - 2:30 am
MAD
-
VVI
11h 30mnonstop
$832Iberia
Mon, May 4 - Sun, May 24
Air Europa Logo
1:30 pm - 5:10 am
VVI
-
MAD
10h 40mnonstop
Air Europa Logo
11:35 pm - 4:50 am
MAD
-
VVI
11h 15mnonstop
$966Air Europa
Tue, Mar 24 - Wed, Apr 8
Iberia Logo
10:05 pm - 1:55 pm
VVI
-
MAD
10h 50mnonstop
Iberia Logo
9:00 pm - 2:30 am
MAD
-
VVI
11h 30mnonstop
$990Iberia
Thu, Mar 26 - Sun, Apr 12
LATAM Airlines Logo
5:25 am - 5:40 am
VVI
-
MAD
19h 15m1 stop
LATAM Airlines Logo
11:59 pm - 4:35 am
MAD
-
VVI
34h 36m1 stop
$1,017LATAM Airlines
Sat, Mar 28 - Sun, Apr 5
Avianca Logo
3:40 am - 1:25 pm
VVI
-
MAD
28h 45m1 stop
Avianca Logo
6:35 am - 2:35 am
MAD
-
VVI
25h 00m1 stop
$1,043Avianca
Sun, Mar 1 - Sun, Mar 22
Avianca Logo
3:40 am - 11:20 pm
VVI
-
MAD
14h 40m1 stop
Avianca Logo
6:35 am - 2:35 am
MAD
-
VVI
25h 00m1 stop
$1,044Avianca
Mon, Feb 23 - Mon, Mar 23
Multiple Airlines Logo
1:30 pm - 5:10 am
VVI
-
MAD
10h 40mnonstop
Multiple Airlines Logo
9:40 am - 1:50 am
MAD
-
VVI
22h 10m1 stop
$1,074Multiple Airlines
Tue, Mar 24 - Mon, Apr 13
Iberia Logo
10:05 pm - 1:55 pm
VVI
-
MAD
10h 50mnonstop
Iberia Logo
9:00 pm - 3:00 am
MAD
-
VVI
11h 00mnonstop
$1,076Iberia
Thu, Feb 12 - Sun, Feb 22
LATAM Airlines Logo
11:15 am - 5:20 am
VVI
-
MAD
36h 05m1 stop
LATAM Airlines Logo
1:20 pm - 7:56 am
MAD
-
VVI
24h 36m1 stop
$1,104LATAM Airlines
Thu, May 28 - Tue, Jun 30
LATAM Airlines Logo
5:25 am - 10:00 am
VVI
-
MAD
22h 35m2 stops
LATAM Airlines Logo
1:45 am - 4:35 am
MAD
-
VVI
32h 50m1 stop
$1,126LATAM Airlines
Fri, Apr 10 - Tue, Apr 21

Iberia flights from Santa Cruz de la Sierra to Madrid

Our best Iberia deals on Santa Cruz de la Sierra to Madrid flight tickets
Iberia
May 4
VVI9:15 pmSanta Cruz de la Sierra Viru Viru Intl
10h 40m
MAD1:55 pmMadrid Barajas
May 24
MAD9:00 pmMadrid Barajas
11h 30m
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
$832
Find similar
Iberia
Mar 26
VVI10:05 pmSanta Cruz de la Sierra Viru Viru Intl
10h 50m
MAD1:55 pmMadrid Barajas
Apr 12
MAD9:00 pmMadrid Barajas
11h 30m
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
$990
Find similar
Iberia
Feb 12
VVI10:05 pmSanta Cruz de la Sierra Viru Viru Intl
10h 50m
MAD1:55 pmMadrid Barajas
Feb 22
MAD9:00 pmMadrid Barajas
11h 00m
VVI3:00 amSanta Cruz de la Sierra Viru Viru Intl
$1,076
Find similar

Air Europa flights from Santa Cruz de la Sierra to Madrid

Our best Air Europa deals on Santa Cruz de la Sierra to Madrid flight tickets
Air Europa
Mar 24
VVI1:30 pmSanta Cruz de la Sierra Viru Viru Intl
10h 40m
MAD5:10 amMadrid Barajas
Apr 8
MAD11:35 pmMadrid Barajas
11h 15m
VVI4:50 amSanta Cruz de la Sierra Viru Viru Intl
$966
Find similar
Air Europa
Feb 24
VVI1:30 pmSanta Cruz de la Sierra Viru Viru Intl
10h 40m
MAD5:10 amMadrid Barajas
Mar 23
MAD11:35 pmMadrid Barajas
11h 20m
VVI5:55 amSanta Cruz de la Sierra Viru Viru Intl
$1,282
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/4

9:15 pm-1:55 pm

Nonstop10h 40m

Madrid Barajas

Sun 5/24

9:00 pm-2:30 am

Nonstop11h 30m

$832

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

1:30 pm-5:10 am

Nonstop10h 40m

Madrid Barajas

Wed 4/8

11:35 pm-4:50 am

Nonstop11h 15m

$966

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/26

10:05 pm-1:55 pm

Nonstop10h 50m

Madrid Barajas

Sun 4/12

9:00 pm-2:30 am

Nonstop11h 30m

$990

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/28

5:25 am-5:40 am

1 stop19h 15m

Madrid Barajas

Sun 4/5

11:59 pm-4:35 am

1 stop34h 36m

$1,017

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/1

3:40 am-1:25 pm

1 stop28h 45m

Madrid Barajas

Sun 3/22

6:35 am-2:35 am

1 stop25h 00m

$1,043

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/23

3:40 am-11:20 pm

1 stop14h 40m

Madrid Barajas

Mon 3/23

6:35 am-2:35 am

1 stop25h 00m

$1,044

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

1:30 pm-5:10 am

Nonstop10h 40m

Madrid Barajas

Mon 4/13

9:40 am-1:50 am

1 stop22h 10m

$1,074

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/12

10:05 pm-1:55 pm

Nonstop10h 50m

Madrid Barajas

Sun 2/22

9:00 pm-3:00 am

Nonstop11h 00m

$1,076

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Thu 5/28

11:15 am-5:20 am

1 stop36h 05m

Madrid Barajas

Tue 6/30

1:20 pm-7:56 am

1 stop24h 36m

$1,104

Santa Cruz de la SierraMadrid

VVI - MAD

VVIMAD

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/10

5:25 am-10:00 am

2 stops22h 35m

Madrid Barajas

Tue 4/21

1:45 am-4:35 am

1 stop32h 50m

$1,126

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Madrid from

How to get the cheapest flight ticket from Santa Cruz de la Sierra to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of April is, on average, the cheapest month to fly to Madrid from Santa Cruz de la Sierra, with most prices found around $968. If you don’t want to visit Madrid in April, then you should wait until December to fly from Santa Cruz de la Sierra, when ticket prices are also cheap, with an average price of $970.

What is the cheapest day to depart on your flight to Madrid?

The cheapest day to depart on your flight to Madrid is on a Wednesday when prices can be found for as low as $1,102. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Monday is $1,360.

What is the cheapest time of day to depart on your flight to Madrid?

Flying to Madrid from Santa Cruz de la Sierra in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $1,087 when looking at flights departing in the afternoon. Flights to Madrid are more costly in the morning, with an average ticket price of $1,446. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas flight route?

Fly from Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas for the best Santa Cruz de la Sierra Viru Viru Intl - Madrid Barajas flight prices

How far in advance should I book a flight to Madrid?

You are more likely to see cheaper flights to Madrid from Santa Cruz de la Sierra when booking weeks ahead of your departure date. In general, you can expect to find flights to Madrid for around $1,131 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Madrid from Santa Cruz de la Sierra for as low as $898 on momondo.

What cabin class options are available on Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas flights?

There are 2 cabin classes available to choose from on Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Santa Cruz de la Sierra to Madrid flights?

No. A direct flight is the cheapest option for a flight between Santa Cruz de la Sierra to Madrid.

How have Santa Cruz de la Sierra to Madrid flight prices changed over time?

As of December 2025, prices for Santa Cruz de la Sierra to Madrid flights are approximately 5% more expensive when compared to flights at the same time last year.

When to book flights from Santa Cruz de la Sierra to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Cruz de la Sierra to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Cruz de la Sierra to Madrid (VVI to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Cruz de la Sierra to Madrid

Best Price Found

$515

Fastest flight time

10h 40m

Direct flights

Mon, Tue, Wed, Fri and Sun

Airports in Madrid

1 airport
The best one-way flight to Madrid from Santa Cruz de la Sierra in the past 72 hours is $515. The best round-trip flight deal from Santa Cruz de la Sierra to Madrid found on momondo in the last 72 hours is $850.
The fastest flight from Santa Cruz de la Sierra to Madrid takes 10h 40m
Direct flights go from Santa Cruz de la Sierra to Madrid on Monday, Tuesday, Wednesday, Friday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Madrid. From Santa Cruz de la Sierra there are direct flights to Madrid Barajas (MAD).
Search flight deals

  • How far is Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas by plane?

    The straight-line distance from Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas is 5537.8 mi. Flights usually cover this in 10h 40m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Madrid Barajas Airport?

    Prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Madrid Barajas Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Santa Cruz de la Sierra Viru Viru Intl Airport to Madrid Barajas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Cruz de la Sierra Viru Viru Intl Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The travel and health documents required for your trip to Madrid Barajas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Madrid Barajas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Santa Cruz de la Sierra to Madrid?

  • What is the most popular airline from Santa Cruz de la Sierra to Madrid?

Best airlines flying from Santa Cruz de la Sierra to Madrid

Compare and see reviews for airlines that fly from Santa Cruz de la Sierra to Madrid with momondo
Airline
Rating
Free Cancellation
Price
IberiaPriceFrom $661Free CancellationRating
7.0
3,045 reviews
Search Iberia flights
AviancaPriceFrom $854Free CancellationRating
6.6
2,480 reviews
Search Avianca flights
Air EuropaPriceFrom $885Free CancellationRating
7.0
571 reviews
Search Air Europa flights
BoAPriceFrom $995Free CancellationRating
6.6
137 reviews
Search BoA flights

  • Iberia Flights From Santa Cruz de la Sierra to Madrid

    The lowest priced Iberia flight from Santa Cruz de la Sierra to Madrid from the last 72 hours was $661. Generally, Iberia has 3 flights on this route every week with an average price of $832. Iberia is rated 7.0/10 by our users.

  • Air Europa Flights From Santa Cruz de la Sierra to Madrid

    Across 571 Air Europa reviews on momondo, the average score is 7.0/10. Air Europa flies from Santa Cruz de la Sierra to Madrid about 2 times each week, with ticket deals ranging from $885 to $1,168. Price data is based on momondo searches in the last 72 hours.

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Getafe
Fuenlabrada
San Lorenzo de El Escorial
Cuenca
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Santa Cruz de la Sierra to Madrid?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Madrid from Santa Cruz de la Sierra.

Can I find flights from Santa Cruz de la Sierra to Madrid with flexible booking policies on momondo?

All flight searches from Santa Cruz de la Sierra to Madrid on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Cruz de la Sierra to Madrid?

momondo provides multiple filters to help you find the best flight to Madrid from Santa Cruz de la Sierra. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Cruz de la Sierra to Madrid right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Santa Cruz de la Sierra to Madrid flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo
Air Europa
Avianca
BoA
Iberia