Cheap flights from Quito to Panama City from $146

In general, March is the cheapest month to fly from Quito to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $355. If you’re not able to fly to Panama City in March, then July is your next best option. Flight prices from Quito to Panama City during July average around $384.

Our data shows that Thursday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $466. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $504. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Quito to Panama City during this time can be as low as $441. Try not to purchase tickets at noon because they tend to be around $556. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Quito Mariscal Sucr to Panama City Tocumen Intl for the best Quito Mariscal Sucr - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Quito when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $415 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Quito for as low as $380 on momondo.

There are 3 cabin classes available to choose from on Quito to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Quito to Panama City.

As of July 2026, prices for Quito to Panama City flights are approximately 29% more expensive when compared to flights at the same time last year.

Historically, on average around 6% of flights between Quito and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 119 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 4% of their flights experiencing any sort of delay.

As of July 2026, there are 11 flights per day flying from Quito to Panama City. The most common time of day flights depart is 3:00PM, with 51% of flights taking off in the afternoon.

The number of flights available between Quito and Panama City is 80 per week as of July 2026. The most frequent departure day is Wed, with 18% of weekly flights leaving on this day.