What is the cheapest airline that flies from Missouri to Panama City Tocumen Intl?

United Airlines, American Airlines, and GOL are the most popular carriers operating from Missouri to Panama City Tocumen Intl

What airlines fly to Panama City?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama City from Missouri according to our data. United Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

How long does it take to fly to Panama City?

If you’re flying from a popular airport in Missouri, such as St. Louis or Kansas City, and flying into Panama City, then you can expect flight times to average 6h 59m and 7h 17m, respectively.

When did momondo last update prices for flights from Missouri to Panama City Tocumen Intl Airport?

Prices for flights from Missouri to Panama City Tocumen Intl Airport were last updated today.

How many operators does momondo search for flights from Missouri to Panama City Tocumen Intl Airport?

As of September 2026, there are 4 operators available to choose from for flights from Missouri to Panama City Tocumen Intl Airport.

How old do you have to be to fly from Missouri to Panama City Tocumen Intl Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$305 Cheap Flights from Missouri to Panama City in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Panama City

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:10 am - 5:12 pmMCI Kansas City-PTY Panama City Tocumen Intl

10h 02m1 stop Houston George Bush Intcntl

8:55 am - 6:24 pmPTY Panama City Tocumen Intl-MCI Kansas City

10h 29m1 stop Houston George Bush Intcntl

$607United Airlines

Thu, Jan 21 - Tue, Feb 2

6:10 am - 2:45 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 35m1 stop Houston George Bush Intcntl

8:55 am - 10:07 pmPTY Panama City Tocumen Intl-MCI Kansas City

14h 12m1 stop Houston George Bush Intcntl

$607United Airlines

Wed, Feb 24 - Wed, Mar 10

4:12 pm - 2:13 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

21h 01m2 stops New York LaGuardia Miami

3:13 pm - 8:21 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

18h 08m2 stops Miami Charlotte Douglas

$611American Airlines

Tue, Dec 1 - Wed, Dec 9

4:12 pm - 2:13 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

21h 01m2 stops New York LaGuardia Miami

3:13 pm - 8:21 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

18h 08m2 stops Miami Charlotte Douglas

$611American Airlines

Tue, Dec 1 - Wed, Dec 9

5:40 am - 2:03 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 23m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 11:56 pmPTY Panama City Tocumen Intl-MCI Kansas City

9h 27m1 stop Atlanta Hartsfield-Jackson

$641Delta

Fri, Dec 4 - Mon, Dec 7

11:50 am - 1:55 amMCI Kansas City-PTY Panama City Tocumen Intl

14h 05m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

5:30 am - 7:55 pmPTY Panama City Tocumen Intl-MCI Kansas City

14h 25m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$678Avianca

Sat, Oct 24 - Sat, Oct 31

5:40 am - 1:55 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 15m1 stop Atlanta Hartsfield-Jackson

1:40 pm - 9:35 amPTY Panama City Tocumen Intl-MCI Kansas City

20h 55m1 stop Atlanta Hartsfield-Jackson

$686Delta

Sat, Jan 9 - Sat, Jan 16

11:33 am - 2:10 amMCI Kansas City-PTY Panama City Tocumen Intl

13h 37m2 stops Washington, D.C. Dulles Intl San Salvador El Salvador Intl

5:30 am - 7:55 pmPTY Panama City Tocumen Intl-MCI Kansas City

15h 25m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$688Avianca

Fri, Nov 6 - Fri, Nov 13

9:35 am - 2:45 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

28h 10m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

11:35 am - 10:30 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

11h 55m1 stop Houston George Bush Intcntl

$730Copa Airlines

Tue, Dec 22 - Mon, Dec 28

6:58 pm - 7:38 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

23h 40m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

4:41 pm - 10:42 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

19h 01m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$750Copa Airlines

Tue, Dec 22 - Mon, Dec 28

Cheap last minute flights

Enter your travel dates to find the best prices.

9:30 am - 7:31 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

10h 01m1 stop Newark

8:55 am - 4:50 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

8h 55m1 stop Houston George Bush Intcntl

$652United Airlines

Mon, Sep 28 - Wed, Nov 11

11:10 am - 6:37 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 27m1 stop Houston George Bush Intcntl

8:55 am - 4:50 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

8h 55m1 stop Houston George Bush Intcntl

$652United Airlines

Mon, Sep 28 - Thu, Nov 12

11:10 am - 6:37 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 27m1 stop Houston George Bush Intcntl

4:41 pm - 2:34 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

22h 53m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$656United Airlines

Mon, Sep 28 - Thu, Nov 12

6:00 am - 12:58 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

6h 58m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 4:23 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

25h 54m1 stop Atlanta Hartsfield-Jackson

$695Delta

Mon, Sep 28 - Sun, Nov 15

4:22 pm - 12:26 pmMCI Kansas City-PTY Panama City Tocumen Intl

20h 04m2 stops Washington, D.C. Reagan-National Miami

1:16 pm - 10:40 amPTY Panama City Tocumen Intl-MCI Kansas City

21h 24m2 stops Miami Dallas/Fort Worth

$721American Airlines

Mon, Sep 28 - Fri, Oct 2

5:00 pm - 12:26 pmMCI Kansas City-PTY Panama City Tocumen Intl

19h 26m1 stop Miami

1:16 pm - 12:18 pmPTY Panama City Tocumen Intl-MCI Kansas City

23h 02m2 stops Miami Dallas/Fort Worth

$738American Airlines

Mon, Sep 28 - Fri, Oct 2

5:44 am - 12:58 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 14m1 stop Atlanta Hartsfield-Jackson

2:23 pm - 11:51 pmPTY Panama City Tocumen Intl-MCI Kansas City

9h 28m1 stop Atlanta Hartsfield-Jackson

$761Delta

Mon, Sep 28 - Fri, Oct 2

5:46 pm - 2:55 pmMCI Kansas City-PTY Panama City Tocumen Intl

21h 09m2 stops Washington, D.C. Dulles Intl San José Juan Santamaria Intl

11:25 am - 2:37 pmPTY Panama City Tocumen Intl-MCI Kansas City

27h 12m3 stops San José Juan Santamaria Intl San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$1,068Avianca

Mon, Sep 28 - Fri, Oct 2

5:46 pm - 12:35 amMCI Kansas City-PTY Panama City Tocumen Intl

30h 49m3 stops Washington, D.C. Dulles Intl San José Juan Santamaria Intl Bogotá El Dorado

11:25 am - 2:37 pmPTY Panama City Tocumen Intl-MCI Kansas City

27h 12m3 stops San José Juan Santamaria Intl San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$1,081Avianca

Mon, Sep 28 - Fri, Oct 2

6:49 pm - 12:26 pmSGF Springfield-Branson-PTY Panama City Tocumen Intl

17h 37m3 stops Dallas/Fort Worth Houston George Bush Intcntl Miami

1:16 pm - 11:58 pmPTY Panama City Tocumen Intl-SGF Springfield-Branson

10h 42m2 stops Miami Dallas/Fort Worth

$3,216American Airlines

Mon, Sep 28 - Thu, Oct 1

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

United Airlines flights from Missouri to Panama City

Our best United Airlines deals on Missouri to Panama City flight tickets

United Airlines

Dec 1

STL6:00 amLambert-St Louis

10h 12m

1 stop

PTY5:12 pmPanama City Tocumen Intl

Dec 9

PTY8:55 amPanama City Tocumen Intl

14h 35m

1 stop

STL10:30 pmLambert-St Louis

$607

United Airlines

Dec 1

STL6:00 amLambert-St Louis

10h 12m

1 stop

PTY5:12 pmPanama City Tocumen Intl

Dec 9

PTY4:41 pmPanama City Tocumen Intl

20h 41m

2 stops

STL12:22 pmLambert-St Louis

$611

United Airlines

Dec 7

MCI6:15 amKansas City

9h 57m

1 stop

PTY5:12 pmPanama City Tocumen Intl

Dec 14

PTY4:41 pmPanama City Tocumen Intl

22h 31m

1 stop

MCI2:12 pmKansas City

$617

American Airlines flights from Missouri to Panama City

Our best American Airlines deals on Missouri to Panama City flight tickets

American Airlines

Jan 21

MCI5:13 pmKansas City

21h 42m

1 stop

PTY3:55 pmPanama City Tocumen Intl

Feb 2

PTY2:25 pmPanama City Tocumen Intl

10h 34m

1 stop

MCI11:59 pmKansas City

$621

American Airlines

Jan 10

SGF4:36 pmSpringfield-Branson

22h 19m

2 stops

PTY3:55 pmPanama City Tocumen Intl

Jan 18

PTY4:55 pmPanama City Tocumen Intl

20h 08m

2 stops

SGF12:03 pmSpringfield-Branson

$694

American Airlines

Dec 1

COU5:08 pmColumbia Regional

20h 05m

2 stops

PTY2:13 pmPanama City Tocumen Intl

Jan 25

PTY4:55 pmPanama City Tocumen Intl

18h 03m

2 stops

COU9:58 amColumbia Regional

$695

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Thu 1/21

6:10 am-5:12 pm

1 stop10h 02m

Panama City Tocumen Intl

Tue 2/2

8:55 am-6:24 pm

1 stop10h 29m

$607

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Wed 2/24

6:10 am-2:45 pm

1 stop7h 35m

Panama City Tocumen Intl

Wed 3/10

8:55 am-10:07 pm

1 stop14h 12m

$607

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Tue 12/1

4:12 pm-2:13 pm

2 stops21h 01m

Panama City Tocumen Intl

Wed 12/9

3:13 pm-8:21 am

2 stops18h 08m

$611

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Tue 12/1

4:12 pm-2:13 pm

2 stops21h 01m

Panama City Tocumen Intl

Wed 12/9

3:13 pm-8:21 am

2 stops18h 08m

$611

Quickest round-trip

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Fri 12/4

5:40 am-2:03 pm

1 stop7h 23m

Panama City Tocumen Intl

Mon 12/7

3:29 pm-11:56 pm

1 stop9h 27m

$641

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Sat 10/24

11:50 am-1:55 am

2 stops14h 05m

Panama City Tocumen Intl

Sat 10/31

5:30 am-7:55 pm

2 stops14h 25m

$678

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Sat 1/9

5:40 am-1:55 pm

1 stop7h 15m

Panama City Tocumen Intl

Sat 1/16

1:40 pm-9:35 am

1 stop20h 55m

$686

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Fri 11/6

11:33 am-2:10 am

2 stops13h 37m

Panama City Tocumen Intl

Fri 11/13

5:30 am-7:55 pm

2 stops15h 25m

$688

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Tue 12/22

9:35 am-2:45 pm

2 stops28h 10m

Panama City Tocumen Intl

Mon 12/28

11:35 am-10:30 pm

1 stop11h 55m

$730

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Tue 12/22

6:58 pm-7:38 pm

2 stops23h 40m

Panama City Tocumen Intl

Mon 12/28

4:41 pm-10:42 am

2 stops19h 01m

$750

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama City?

In general, November is the cheapest month to fly from Missouri to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $510. If you’re not able to fly to Panama City in November, then April is your next best option. Flight prices from Missouri to Panama City during April average around $529.

Can stopping save me money on Missouri to Panama City flights?

You could potentially save up to 46% on your flight if you consider stops on a Missouri to Panama City flight.

Cheap Missouri to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama City

Best Price Found	$305
Fastest flight time	6h 59m
Direct flights	None

The best one-way flight to Panama City from Missouri in the past 72 hours is $305. The best round-trip flight deal from Missouri to Panama City found on momondo in the last 72 hours is $607.

The fastest flight from Missouri to Panama City takes 6h 59m

There are no direct flights from Missouri to Panama City. There are no popular flight routes from Missouri to Panama City.

Search flight deals

Frequently asked questions about flying from Missouri to Panama City

When did momondo last update prices for flights from Missouri to Panama City Tocumen Intl Airport?
Prices for flights from Missouri to Panama City Tocumen Intl Airport were last updated today.
How many operators does momondo search for flights from Missouri to Panama City Tocumen Intl Airport?
As of September 2026, there are 4 operators available to choose from for flights from Missouri to Panama City Tocumen Intl Airport.
How old do you have to be to fly from Missouri to Panama City Tocumen Intl Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Panama City

Compare and see reviews for airlines that fly from Missouri to Panama City with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $393	Free Cancellation	Rating 7.0 12,098 reviews	Search American Airlines flights
United Airlines	PriceFrom $393	Free Cancellation	Rating 7.4 10,246 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $446	Free Cancellation	Rating 7.6 1,544 reviews	Search Copa Airlines flights
Delta	PriceFrom $461	Free Cancellation	Rating 7.8 8,605 reviews	Search Delta flights

San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Missouri.

Can I find flights from Missouri to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Missouri with this policy.

How can momondo help me find flights from Missouri to Panama City?

Once all potential Missouri to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Tue 10/27

Tue 11/3

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Nearby airports

Airlines

Cabin classes

Other Panama destinations

Other flights from Missouri

Complete your trip

Feeling lucky

Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from Missouri to Panama City from $305

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama City departing on 1/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Missouri to Panama City

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

United Airlines flights from Missouri to Panama City

Our best United Airlines deals on Missouri to Panama City flight tickets

American Airlines flights from Missouri to Panama City

Our best American Airlines deals on Missouri to Panama City flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Missouri to Panama City that are best for you.

See travel insights to Panama City from

How to get the cheapest flight ticket from Missouri to Panama City

What is the cheapest month to fly to Panama City?

Can stopping save me money on Missouri to Panama City flights?

What is the cheapest airline that flies from Missouri to Panama City Tocumen Intl?

What airlines fly to Panama City?

How long does it take to fly to Panama City?

Cheap Missouri to Panama City flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Missouri to Panama City

Best airlines flying from Missouri to Panama City

Compare and see reviews for airlines that fly from Missouri to Panama City with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Airports servicing Panama

Fly your favorite airline to Panama City

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama City

List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Missouri

According to popular flight searches on momondo this year

Complete your trip to Panama City

Explore popular destinations other users love

According to popular flight searches on momondo this year