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Cheap flights from Missouri to Panama City from $235

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama City departing on 7/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Missouri to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:11 am - 2:10 pm
MCI
-
PTY
8h 59m
1 stop
American Airlines Logo
3:40 pm - 11:38 pm
PTY
-
MCI
7h 58m
1 stop
$467American Airlines
Tue, Sep 15 - Fri, Oct 2
American Airlines Logo
5:20 pm - 2:10 pm
MCI
-
PTY
20h 50m
2 stops
American Airlines Logo
3:40 pm - 10:37 am
PTY
-
MCI
18h 57m
2 stops
$471American Airlines
Tue, Sep 15 - Fri, Oct 2
United Airlines Logo
8:30 am - 6:37 pm
MCI
-
PTY
10h 07m
1 stop
United Airlines Logo
3:30 pm - 10:03 am
PTY
-
MCI
18h 33m
1 stop
$487United Airlines
Thu, Jul 16 - Tue, Jul 21
United Airlines Logo
6:16 am - 6:37 pm
MCI
-
PTY
12h 21m
1 stop
United Airlines Logo
10:55 pm - 4:00 pm
PTY
-
MCI
17h 05m
2 stops
$491United Airlines
Wed, Jul 15 - Tue, Jul 21
American Airlines Logo
7:49 pm - 2:00 pm
MCI
-
PTY
18h 11m
2 stops
American Airlines Logo
3:35 pm - 10:42 am
PTY
-
MCI
19h 07m
2 stops
$505American Airlines
Thu, Oct 8 - Mon, Oct 12
Delta Logo
5:40 am - 1:02 pm
MCI
-
PTY
7h 22m
1 stop
Delta Logo
2:15 pm - 11:49 pm
PTY
-
MCI
9h 34m
1 stop
$517Delta
Wed, Apr 29 - Wed, May 13
American Airlines Logo
4:16 pm - 12:24 pm
MCI
-
PTY
20h 08m
2 stops
American Airlines Logo
1:24 pm - 1:20 pm
PTY
-
MCI
23h 56m
2 stops
$521American Airlines
Wed, Aug 19 - Sun, Aug 30
United Airlines Logo
6:14 am - 2:14 pm
STL
-
PTY
8h 00m
1 stop
United Airlines Logo
8:55 am - 4:35 pm
PTY
-
STL
8h 40m
1 stop
$525United Airlines
Mon, Sep 14 - Thu, Dec 17
Delta Logo
6:47 pm - 1:02 pm
MCI
-
PTY
18h 15m
1 stop
Delta Logo
2:15 pm - 11:49 pm
PTY
-
MCI
9h 34m
1 stop
$526Delta
Sun, May 3 - Wed, May 13
Delta Logo
1:30 pm - 12:56 pm
STL
-
PTY
23h 26m
1 stop
Delta Logo
3:30 pm - 11:39 pm
PTY
-
STL
9h 09m
1 stop
$533Delta
Sun, Sep 13 - Tue, Dec 15

Delta flights from Missouri to Panama City

Our best Delta deals on Missouri to Panama City flight tickets
Delta
Apr 29
MCI5:40 amKansas City
7h 22m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 13
PTY2:15 pmPanama City Tocumen Intl
9h 34m
1 stop
MCI11:49 pmKansas City
$517
Delta
Sep 14
STL6:00 amLambert-St Louis
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Dec 14
PTY3:30 pmPanama City Tocumen Intl
9h 09m
1 stop
STL11:39 pmLambert-St Louis
$525
Delta
May 3
MCI6:47 pmKansas City
18h 15m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 13
PTY2:15 pmPanama City Tocumen Intl
9h 34m
1 stop
MCI11:49 pmKansas City
$526

United Airlines flights from Missouri to Panama City

Our best United Airlines deals on Missouri to Panama City flight tickets
United Airlines
Jul 16
MCI8:30 amKansas City
10h 07m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jul 21
PTY3:30 pmPanama City Tocumen Intl
18h 33m
1 stop
MCI10:03 amKansas City
$487
United Airlines
Jul 15
MCI6:16 amKansas City
12h 21m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jul 21
PTY10:55 pmPanama City Tocumen Intl
17h 05m
2 stops
MCI4:00 pmKansas City
$491
United Airlines
Aug 19
MCI6:23 amKansas City
12h 14m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Aug 23
PTY3:30 pmPanama City Tocumen Intl
22h 47m
2 stops
MCI2:17 pmKansas City
$505

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Missouri to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Tue 9/15

5:11 am-2:10 pm

1 stop8h 59m

Panama City Tocumen Intl

Fri 10/2

3:40 pm-11:38 pm

1 stop7h 58m

$467

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Tue 9/15

5:20 pm-2:10 pm

2 stops20h 50m

Panama City Tocumen Intl

Fri 10/2

3:40 pm-10:37 am

2 stops18h 57m

$471

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Thu 7/16

8:30 am-6:37 pm

1 stop10h 07m

Panama City Tocumen Intl

Tue 7/21

3:30 pm-10:03 am

1 stop18h 33m

$487

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Wed 7/15

6:16 am-6:37 pm

1 stop12h 21m

Panama City Tocumen Intl

Tue 7/21

10:55 pm-4:00 pm

2 stops17h 05m

$491

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Thu 10/8

7:49 pm-2:00 pm

2 stops18h 11m

Panama City Tocumen Intl

Mon 10/12

3:35 pm-10:42 am

2 stops19h 07m

$505

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Wed 4/29

5:40 am-1:02 pm

1 stop7h 22m

Panama City Tocumen Intl

Wed 5/13

2:15 pm-11:49 pm

1 stop9h 34m

$517

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Wed 8/19

4:16 pm-12:24 pm

2 stops20h 08m

Panama City Tocumen Intl

Sun 8/30

1:24 pm-1:20 pm

2 stops23h 56m

$521
Quickest round-trip

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 9/14

6:14 am-2:14 pm

1 stop8h 00m

Panama City Tocumen Intl

Thu 12/17

8:55 am-4:35 pm

1 stop8h 40m

$525

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

Sun 5/3

6:47 pm-1:02 pm

1 stop18h 15m

Panama City Tocumen Intl

Wed 5/13

2:15 pm-11:49 pm

1 stop9h 34m

$526

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 9/13

1:30 pm-12:56 pm

1 stop23h 26m

Panama City Tocumen Intl

Tue 12/15

3:30 pm-11:39 pm

1 stop9h 09m

$533

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Missouri to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, April is the cheapest month to fly from Missouri to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $488. If you’re not able to fly to Panama City in April, then November is your next best option. Flight prices from Missouri to Panama City during November average around $510.

Can stopping save me money on Missouri to Panama City flights?

You could potentially save up to 35% on your flight if you consider stops on a Missouri to Panama City flight.

Cheap Missouri to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama City

Fastest flight time

7h 33m

Direct flights

None
The fastest flight from Missouri to Panama City takes 7h 33m
There are no direct flights from Missouri to Panama City. There are no popular flight routes from Missouri to Panama City.
Search flight deals

Frequently asked questions about flying from Missouri to Panama City

  • When did momondo last update prices for flights from Missouri to Panama City Tocumen Intl Airport?

    Prices for flights from Missouri to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Missouri to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Missouri to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Panama City

Compare and see reviews for airlines that fly from Missouri to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $373Free CancellationRating
7.9
8,424 reviews
Search Delta flights
United AirlinesPriceFrom $393Free CancellationRating
7.4
9,605 reviews
Search United Airlines flights
American AirlinesPriceFrom $393Free CancellationRating
7.1
11,604 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Missouri.

Can I find flights from Missouri to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Missouri with this policy.

How can momondo help me find flights from Missouri to Panama City?

Once all potential Missouri to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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