How long does it take to fly to Panama City?

If you’re flying from a popular airport in Missouri, such as Kansas City or Springfield, and flying into Panama City, then you can expect flight times to average 7h 30m and 7h 39m, respectively.

What airlines fly to Panama City?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama City from Missouri according to our data. United Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 4 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Missouri to Panama City Tocumen Intl?

United Airlines and American Airlines are the most popular carriers operating from Missouri to Panama City Tocumen Intl

When did momondo last update prices for flights from Missouri to Panama City Tocumen Intl Airport?

Prices for flights from Missouri to Panama City Tocumen Intl Airport were last updated today.

How many operators does momondo search for flights from Missouri to Panama City Tocumen Intl Airport?

As of November 2026, there are 4 operators available to choose from for flights from Missouri to Panama City Tocumen Intl Airport.

How old do you have to be to fly from Missouri to Panama City Tocumen Intl Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$271 Cheap Flights from Missouri to Panama City in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Panama City

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:00 am - 1:25 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 25m1 stop Miami

2:25 pm - 11:39 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

10h 14m1 stop Miami

$607American Airlines

Sun, Feb 14 - Mon, Feb 22

6:15 am - 2:45 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 30m1 stop Houston George Bush Intcntl

4:41 pm - 9:31 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

17h 50m1 stop Houston George Bush Intcntl

$607United Airlines

Mon, Jan 11 - Wed, Jan 20

6:10 am - 7:38 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

12h 28m1 stop Houston George Bush Intcntl

8:55 am - 4:46 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

8h 51m1 stop Houston George Bush Intcntl

$607United Airlines

Mon, Feb 15 - Wed, Feb 24

5:46 pm - 1:25 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

18h 39m2 stops Dallas/Fort Worth Miami

2:25 pm - 8:40 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

19h 15m2 stops Miami New York LaGuardia

$612American Airlines

Tue, Mar 2 - Thu, Mar 11

10:05 am - 7:38 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

8h 33m1 stop Houston George Bush Intcntl

8:55 am - 10:25 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

14h 30m1 stop Houston George Bush Intcntl

$656Copa Airlines

Sat, Feb 13 - Sun, Feb 21

9:52 am - 8:02 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

9h 10m1 stop Newark

8:55 am - 10:25 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

14h 30m1 stop Houston George Bush Intcntl

$656Copa Airlines

Mon, Feb 15 - Mon, Feb 22

7:00 am - 9:51 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

13h 51m1 stop Atlanta Hartsfield-Jackson

3:29 pm - 11:26 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

8h 57m1 stop Atlanta Hartsfield-Jackson

$707Delta

Mon, Jan 4 - Wed, Jan 13

5:00 am - 12:36 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 36m1 stop Miami

1:49 pm - 10:21 pmPTY Panama City Tocumen Intl-MCI Kansas City

8h 32m1 stop Miami

$807GOL

Sat, Apr 17 - Sat, Apr 24

5:00 am - 12:36 pmMCI Kansas City-PTY Panama City Tocumen Intl

7h 36m1 stop Miami

1:49 pm - 10:21 pmPTY Panama City Tocumen Intl-MCI Kansas City

8h 32m1 stop Miami

$812GOL

Sat, Apr 17 - Sun, Apr 25

10:29 am - 9:45 pmMCI Kansas City-PTY Panama City Tocumen Intl

10h 16m1 stop Atlanta Hartsfield-Jackson

8:00 am - 4:21 pmPTY Panama City Tocumen Intl-MCI Kansas City

9h 21m1 stop Atlanta Hartsfield-Jackson

$831Delta

Wed, Dec 30 - Thu, Jan 7

Cheap last minute flights

Enter your travel dates to find the best prices.

9:59 am - 8:02 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

9h 03m1 stop Newark

8:55 am - 10:30 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

14h 35m1 stop Houston George Bush Intcntl

$777United Airlines

Thu, Nov 19 - Mon, Dec 7

8:30 am - 7:38 pmMCI Kansas City-PTY Panama City Tocumen Intl

10h 08m1 stop Houston George Bush Intcntl

8:55 am - 4:52 pmPTY Panama City Tocumen Intl-MCI Kansas City

8h 57m1 stop Houston George Bush Intcntl

$777United Airlines

Wed, Nov 18 - Thu, Nov 26

8:30 am - 7:38 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

10h 08m1 stop Houston George Bush Intcntl

10:00 am - 10:59 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

13h 59m2 stops Newark Chicago O'Hare Intl

$782United Airlines

Thu, Nov 19 - Mon, Dec 7

6:00 am - 8:02 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

13h 02m2 stops Chicago O'Hare Intl Newark

4:41 pm - 12:22 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

20h 41m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$782United Airlines

Thu, Nov 19 - Mon, Dec 7

5:00 am - 2:13 pmMCI Kansas City-PTY Panama City Tocumen Intl

8h 13m1 stop Miami

3:34 pm - 6:35 pmPTY Panama City Tocumen Intl-MCI Kansas City

28h 01m2 stops Miami Dallas/Fort Worth

$787American Airlines

Wed, Nov 18 - Thu, Nov 26

3:49 pm - 2:34 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

21h 45m2 stops Washington, D.C. Reagan-National Miami

3:13 pm - 12:25 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

22h 12m2 stops Miami Philadelphia

$816American Airlines

Thu, Nov 19 - Mon, Dec 7

7:36 am - 8:02 pmMCI Kansas City-PTY Panama City Tocumen Intl

11h 26m2 stops Chicago O'Hare Intl Newark

10:00 am - 10:31 amPTY Panama City Tocumen Intl-MCI Kansas City

25h 31m2 stops Newark Chicago O'Hare Intl

$849Copa Airlines

Wed, Nov 18 - Thu, Nov 26

11:29 am - 2:10 amSTL Lambert-St Louis-PTY Panama City Tocumen Intl

13h 41m2 stops Dallas/Fort Worth San Salvador El Salvador Intl

2:30 am - 12:12 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

22h 42m3 stops Bogotá El Dorado Washington, D.C. Dulles Intl Orlando

$1,910Multiple Airlines

Thu, Nov 19 - Sun, Dec 6

8:43 pm - 2:10 amMCI Kansas City-PTY Panama City Tocumen Intl

28h 27m3 stops Denver Intl Miami San Salvador El Salvador Intl

5:30 am - 10:16 amPTY Panama City Tocumen Intl-MCI Kansas City

29h 46m3 stops San Salvador El Salvador Intl Los Angeles Orlando

$1,935Multiple Airlines

Wed, Nov 18 - Thu, Nov 26

4:26 pm - 1:20 amSTL Lambert-St Louis-PTY Panama City Tocumen Intl

31h 54m3 stops Orlando Dallas/Fort Worth Bogotá El Dorado

10:05 am - 10:03 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

24h 58m3 stops Bogotá El Dorado Guatemala City La Aurora Washington, D.C. Dulles Intl

$2,727Multiple Airlines

Thu, Nov 19 - Mon, Dec 7

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United Airlines flights from Missouri to Panama City

Our best United Airlines deals on Missouri to Panama City flight tickets

United Airlines

Feb 11

STL6:10 amLambert-St Louis

12h 28m

1 stop

PTY7:38 pmPanama City Tocumen Intl

Feb 19

PTY8:55 amPanama City Tocumen Intl

8h 51m

1 stop

STL4:46 pmLambert-St Louis

$607

United Airlines

Feb 11

STL10:05 amLambert-St Louis

8h 33m

1 stop

PTY7:38 pmPanama City Tocumen Intl

Feb 23

PTY8:55 amPanama City Tocumen Intl

13h 28m

2 stops

STL9:23 pmLambert-St Louis

$612

United Airlines

Jan 16

STL5:00 pmLambert-St Louis

26h 02m

1 stop

PTY8:02 pmPanama City Tocumen Intl

Feb 13

PTY11:35 amPanama City Tocumen Intl

11h 50m

1 stop

STL10:25 pmLambert-St Louis

$617

American Airlines flights from Missouri to Panama City

Our best American Airlines deals on Missouri to Panama City flight tickets

American Airlines

Feb 19

STL6:09 pmLambert-St Louis

18h 16m

1 stop

PTY1:25 pmPanama City Tocumen Intl

Feb 28

PTY2:25 pmPanama City Tocumen Intl

20h 40m

2 stops

STL10:05 amLambert-St Louis

$630

American Airlines

Feb 19

STL6:09 pmLambert-St Louis

20h 49m

1 stop

PTY3:58 pmPanama City Tocumen Intl

Feb 28

PTY4:24 pmPanama City Tocumen Intl

20h 07m

1 stop

STL11:31 amLambert-St Louis

$640

American Airlines

Jan 21

MCI8:09 pmKansas City

18h 46m

2 stops

PTY3:55 pmPanama City Tocumen Intl

Feb 2

PTY2:26 pmPanama City Tocumen Intl

9h 29m

1 stop

MCI10:55 pmKansas City

$692

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Sun 2/14

5:00 am-1:25 pm

1 stop7h 25m

Panama City Tocumen Intl

Mon 2/22

2:25 pm-11:39 pm

1 stop10h 14m

$607

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Mon 1/11

6:15 am-2:45 pm

1 stop7h 30m

Panama City Tocumen Intl

Wed 1/20

4:41 pm-9:31 am

1 stop17h 50m

$607

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Mon 2/15

6:10 am-7:38 pm

1 stop12h 28m

Panama City Tocumen Intl

Wed 2/24

8:55 am-4:46 pm

1 stop8h 51m

$607

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Tue 3/2

5:46 pm-1:25 pm

2 stops18h 39m

Panama City Tocumen Intl

Thu 3/11

2:25 pm-8:40 am

2 stops19h 15m

$612

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Sat 2/13

10:05 am-7:38 pm

1 stop8h 33m

Panama City Tocumen Intl

Sun 2/21

8:55 am-10:25 pm

1 stop14h 30m

$656

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Mon 2/15

9:52 am-8:02 pm

1 stop9h 10m

Panama City Tocumen Intl

Mon 2/22

8:55 am-10:25 pm

1 stop14h 30m

$656

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Mon 1/4

7:00 am-9:51 pm

1 stop13h 51m

Panama City Tocumen Intl

Wed 1/13

3:29 pm-11:26 pm

1 stop8h 57m

$707

Quickest round-trip

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Sat 4/17

5:00 am-12:36 pm

1 stop7h 36m

Panama City Tocumen Intl

Sat 4/24

1:49 pm-10:21 pm

1 stop8h 32m

$807

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Sat 4/17

5:00 am-12:36 pm

1 stop7h 36m

Panama City Tocumen Intl

Sun 4/25

1:49 pm-10:21 pm

1 stop8h 32m

$812

Kansas CityPanama City

MCI Kansas City - PTY Panama City Tocumen Intl

MCIPTY

Kansas City

Wed 12/30

10:29 am-9:45 pm

1 stop10h 16m

Panama City Tocumen Intl

Thu 1/7

8:00 am-4:21 pm

1 stop9h 21m

$831

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Panama City?

In general, April is the cheapest month to fly from Missouri to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $529. If you’re not able to fly to Panama City in April, then March is your next best option. Flight prices from Missouri to Panama City during March average around $593.

Can stopping save me money on Missouri to Panama City flights?

You could potentially save up to 42% on your flight if you consider stops on a Missouri to Panama City flight.

Cheap Missouri to Panama City flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Panama City

Best Price Found	$271
Fastest flight time	7h 30m
Direct flights	None

The best one-way flight to Panama City from Missouri in the past 72 hours is $271. The best round-trip flight deal from Missouri to Panama City found on momondo in the last 72 hours is $607.

The fastest flight from Missouri to Panama City takes 7h 30m

There are no direct flights from Missouri to Panama City. There are no popular flight routes from Missouri to Panama City.

Search flight deals

Frequently asked questions about flying from Missouri to Panama City

When did momondo last update prices for flights from Missouri to Panama City Tocumen Intl Airport?
Prices for flights from Missouri to Panama City Tocumen Intl Airport were last updated today.
How many operators does momondo search for flights from Missouri to Panama City Tocumen Intl Airport?
As of November 2026, there are 4 operators available to choose from for flights from Missouri to Panama City Tocumen Intl Airport.
How old do you have to be to fly from Missouri to Panama City Tocumen Intl Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The travel and health documents required for your trip to Panama City Tocumen Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City Tocumen Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Panama City

Compare and see reviews for airlines that fly from Missouri to Panama City with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $362	Free Cancellation	Rating 7.0 12,233 reviews	Search American Airlines flights
United Airlines	PriceFrom $393	Free Cancellation	Rating 7.3 10,493 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $446	Free Cancellation	Rating 7.6 1,554 reviews	Search Copa Airlines flights
Delta	PriceFrom $461	Free Cancellation	Rating 7.8 8,719 reviews	Search Delta flights

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Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Missouri.

Can I find flights from Missouri to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Missouri with this policy.

How can momondo help me find flights from Missouri to Panama City?

Once all potential Missouri to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Missouri to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from Missouri to Panama City from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Panama City departing on 4/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Missouri to Panama City

Our best United Airlines deals on Missouri to Panama City flight tickets

American Airlines flights from Missouri to Panama City

Our best American Airlines deals on Missouri to Panama City flight tickets

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How to get the cheapest flight ticket from Missouri to Panama City

What is the cheapest month to fly to Panama City?

Can stopping save me money on Missouri to Panama City flights?

What is the cheapest airline that flies from Missouri to Panama City Tocumen Intl?

What airlines fly to Panama City?

How long does it take to fly to Panama City?

Cheap Missouri to Panama City flight deals and tips

Best Price Found

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Direct flights

Frequently asked questions about flying from Missouri to Panama City

Best airlines flying from Missouri to Panama City

Compare and see reviews for airlines that fly from Missouri to Panama City with momondo

Traveling to a place near Panama City?

Why use momondo?

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Airports servicing Panama

Fly your favorite airline to Panama City

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama City

List of cabin classes available on flights landing in Panama City. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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