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Cheap flights from Medellín Jose Maria Cordova Intl Airport to Panama City from $131

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Medellín Jose Maria Cordova Intl Airport to Panama City departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Medellín Jose Maria Cordova Intl Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
7:55 pm - 12:40 amMDE-PTY
4h 45m1 stop
Avianca Logo
2:55 am - 7:05 amPTY-MDE
4h 10m1 stop
$229Avianca
Find Deal
Fri, Nov 28 - Sun, Nov 30
Avianca Logo
12:40 pm - 4:55 pmMDE-PTY
4h 15m1 stop
Avianca Logo
2:55 am - 7:05 amPTY-MDE
4h 10m1 stop
$235Avianca
Find Deal
Thu, Nov 20 - Sun, Nov 23
Avianca Logo
4:20 am - 8:50 amMDE-PTY
4h 30m1 stop
Avianca Logo
2:55 pm - 6:55 pmPTY-MDE
4h 00m1 stop
$237Avianca
Find Deal
Fri, Jan 9 - Fri, Jan 16
Copa Airlines Logo
10:46 am - 12:14 pmMDE-PTY
1h 28mnonstop
Copa Airlines Logo
6:54 am - 8:18 amPTY-MDE
1h 24mnonstop
$238Copa Airlines
Find Deal
Fri, Nov 14 - Tue, Nov 25
Copa Airlines Logo
10:46 am - 12:14 pmMDE-PTY
1h 28mnonstop
Copa Airlines Logo
6:52 pm - 8:16 pmPTY-MDE
1h 24mnonstop
$239Copa Airlines
Find Deal
Fri, Nov 7 - Wed, Nov 12
Avianca Logo
9:50 am - 2:00 pmMDE-PTY
4h 10m1 stop
Avianca Logo
2:55 pm - 6:55 pmPTY-MDE
4h 00m1 stop
$245Avianca
Find Deal
Fri, Jan 9 - Tue, Jan 13
Avianca Logo
8:10 pm - 12:40 amMDE-PTY
4h 30m1 stop
Avianca Logo
2:55 am - 7:05 amPTY-MDE
4h 10m1 stop
$247Avianca
Find Deal
Fri, Nov 28 - Fri, Dec 5
Copa Airlines Logo
6:20 pm - 7:49 pmMDE-PTY
1h 29mnonstop
Copa Airlines Logo
12:50 pm - 2:15 pmPTY-MDE
1h 25mnonstop
$251Copa Airlines
Find Deal
Sat, Dec 13 - Tue, Dec 16
Copa Airlines Logo
5:00 am - 6:29 amMDE-PTY
1h 29mnonstop
Copa Airlines Logo
6:54 am - 8:18 amPTY-MDE
1h 24mnonstop
$252Copa Airlines
Find Deal
Sat, Dec 13 - Tue, Dec 16
Multiple Airlines Logo
12:42 pm - 2:10 pmMDE-PTY
1h 28mnonstop
Multiple Airlines Logo
5:50 pm - 9:55 pmPTY-MDE
4h 05m1 stop
$273Multiple Airlines
Find Deal
Thu, Nov 20 - Mon, Nov 24

Copa Airlines flights from Medellín Jose Maria Cordova Intl Airport to Panama City

Our best Copa Airlines deals on Medellín Jose Maria Cordova Intl Airport to Panama City flight tickets
Copa Airlines
Nov 14
MDE10:46 amMedellín Jose Maria Cordova Intl
1h 28m
PTY12:14 pmPanama City Tocumen Intl
Nov 25
PTY6:54 amPanama City Tocumen Intl
1h 24m
MDE8:18 amMedellín Jose Maria Cordova Intl
$238
Find similar
Copa Airlines
Nov 7
MDE10:46 amMedellín Jose Maria Cordova Intl
1h 28m
PTY12:14 pmPanama City Tocumen Intl
Nov 12
PTY6:52 pmPanama City Tocumen Intl
1h 24m
MDE8:16 pmMedellín Jose Maria Cordova Intl
$239
Find similar
Copa Airlines
Dec 13
MDE6:20 pmMedellín Jose Maria Cordova Intl
1h 29m
PTY7:49 pmPanama City Tocumen Intl
Dec 16
PTY12:50 pmPanama City Tocumen Intl
1h 25m
MDE2:15 pmMedellín Jose Maria Cordova Intl
$251
Find similar

Avianca flights from Medellín Jose Maria Cordova Intl Airport to Panama City

Our best Avianca deals on Medellín Jose Maria Cordova Intl Airport to Panama City flight tickets
Avianca
Nov 28
MDE7:55 pmMedellín Jose Maria Cordova Intl
4h 45m
1 stop
PTY12:40 amPanama City Tocumen Intl
Nov 30
PTY2:55 amPanama City Tocumen Intl
4h 10m
1 stop
MDE7:05 amMedellín Jose Maria Cordova Intl
$229
Find similar
Avianca
Nov 20
MDE12:40 pmMedellín Jose Maria Cordova Intl
4h 15m
1 stop
PTY4:55 pmPanama City Tocumen Intl
Nov 23
PTY2:55 amPanama City Tocumen Intl
4h 10m
1 stop
MDE7:05 amMedellín Jose Maria Cordova Intl
$235
Find similar
Avianca
Jan 9
MDE4:20 amMedellín Jose Maria Cordova Intl
4h 30m
1 stop
PTY8:50 amPanama City Tocumen Intl
Jan 16
PTY2:55 pmPanama City Tocumen Intl
4h 00m
1 stop
MDE6:55 pmMedellín Jose Maria Cordova Intl
$237
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Medellín Jose Maria Cordova Intl Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Fri 11/28

7:55 pm-12:40 am

1 stop4h 45m

Panama City Tocumen Intl

Sun 11/30

2:55 am-7:05 am

1 stop4h 10m

$229

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Thu 11/20

12:40 pm-4:55 pm

1 stop4h 15m

Panama City Tocumen Intl

Sun 11/23

2:55 am-7:05 am

1 stop4h 10m

$235

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Fri 1/9

4:20 am-8:50 am

1 stop4h 30m

Panama City Tocumen Intl

Fri 1/16

2:55 pm-6:55 pm

1 stop4h 00m

$237

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Fri 11/14

10:46 am-12:14 pm

Nonstop1h 28m

Panama City Tocumen Intl

Tue 11/25

6:54 am-8:18 am

Nonstop1h 24m

$238

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Fri 11/7

10:46 am-12:14 pm

Nonstop1h 28m

Panama City Tocumen Intl

Wed 11/12

6:52 pm-8:16 pm

Nonstop1h 24m

$239

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Fri 1/9

9:50 am-2:00 pm

1 stop4h 10m

Panama City Tocumen Intl

Tue 1/13

2:55 pm-6:55 pm

1 stop4h 00m

$245

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Fri 11/28

8:10 pm-12:40 am

1 stop4h 30m

Panama City Tocumen Intl

Fri 12/5

2:55 am-7:05 am

1 stop4h 10m

$247

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Sat 12/13

6:20 pm-7:49 pm

Nonstop1h 29m

Panama City Tocumen Intl

Tue 12/16

12:50 pm-2:15 pm

Nonstop1h 25m

$251

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Sat 12/13

5:00 am-6:29 am

Nonstop1h 29m

Panama City Tocumen Intl

Tue 12/16

6:54 am-8:18 am

Nonstop1h 24m

$252

MedellínPanama City

MDE - PTY

MDEPTY

Medellín Jose Maria Cordova Intl

Thu 11/20

12:42 pm-2:10 pm

Nonstop1h 28m

Panama City Tocumen Intl

Mon 11/24

5:50 pm-9:55 pm

1 stop4h 05m

$273

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Medellín Jose Maria Cordova Intl Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, May is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $165. If you’re not able to fly to Panama City in May, then February is your next best option. Flight prices from Medellín Jose Maria Cordova Intl Airport to Panama City during February average around $167.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Friday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $346. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $425. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Medellín Jose Maria Cordova Intl Airport to Panama City during this time can be as low as $307. Try not to purchase tickets in the morning because they tend to be around $389. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl flight route?

Fly from Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl for the best Medellín Jose Maria Cordova Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Medellín Jose Maria Cordova Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $187 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Medellín Jose Maria Cordova Intl Airport for as low as $168 on momondo.

What cabin class options are available on Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Medellín Jose Maria Cordova Intl Airport to Panama City flights?

No. A direct flight is the cheapest option for a flight between Medellín Jose Maria Cordova Intl Airport to Panama City.

How have Medellín Jose Maria Cordova Intl Airport to Panama City flight prices changed over time?

As of October 2025, prices for Medellín Jose Maria Cordova Intl Airport to Panama City flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Medellín Jose Maria Cordova Intl Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Medellín Jose Maria Cordova Intl Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Medellín Jose Maria Cordova Intl Airport to Panama City (MDE to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medellín Jose Maria Cordova Intl Airport to Panama City

Best Price Found

$226

Fastest flight time

1h 23m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Medellín Jose Maria Cordova Intl Airport in the past 72 hours is $226. The best round-trip flight deal from Medellín Jose Maria Cordova Intl Airport to Panama City found on momondo in the last 72 hours is $297.
The fastest flight from Medellín Jose Maria Cordova Intl Airport to Panama City takes 1h 23m
Direct flights go from Medellín Jose Maria Cordova Intl Airport to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl by plane?

    The distance between Medellín Jose Maria Cordova Intl and Panama City Tocumen Intl is about 341.6 mi. Typically, this will take 1h 23m by plane in normal conditions.

  • When did momondo last update prices for flights from Medellín Jose Maria Cordova Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Medellín Jose Maria Cordova Intl Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Medellín Jose Maria Cordova Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Medellín Jose Maria Cordova Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Medellín Jose Maria Cordova Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Medellín Jose Maria Cordova Intl Airport to Panama City?

  • What is the most popular airline from Medellín Jose Maria Cordova Intl Airport to Panama City?

Best airlines flying from Medellín Jose Maria Cordova Intl Airport to Panama City

Compare and see reviews for airlines that fly from Medellín Jose Maria Cordova Intl Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
WingoPriceFrom $105Free CancellationRating
0.0
0 reviews
Search Wingo flights
Copa AirlinesPriceFrom $143Free CancellationRating
7.6
1,560 reviews
Search Copa Airlines flights
AviancaPriceFrom $203Free CancellationRating
6.6
2,468 reviews
Search Avianca flights

  • Copa Airlines Flights From Medellín Jose Maria Cordova Intl Airport to Panama City

    Copa Airlines flies from Medellín Jose Maria Cordova Intl Airport to Panama City around 34 times per week, with 1,560 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Medellín Jose Maria Cordova Intl Airport to Panama City in the last 72 hours was $143 (round-trip), much lower than the average airfare cost of $284 for Copa Airlines flights on this route.

Traveling to a place near Panama City?

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Why should I use momondo to find a flight deal from Medellín to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Medellín to Panama City for you.

Can I find flights from Medellín to Panama City with flexible booking policies on momondo?

All flight searches from Medellín to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Medellín to Panama City?

Once all potential Medellín to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Medellín to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Medellín to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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