Cheap flights from Medellín Jose Maria Cordova Intl Airport to Panama City from $166

In general, May is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $173. If you’re not able to fly to Panama City in May, then April is your next best option. Flight prices from Medellín Jose Maria Cordova Intl Airport to Panama City during April average around $175.

Our data shows that Friday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $353. If your travel schedule is flexible, try to avoid departing on a Tuesday because tickets tend to average around $406. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Medellín Jose Maria Cordova Intl Airport to Panama City during this time can be as low as $280. Try not to purchase tickets in the morning because they tend to be around $375. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl for the best Medellín Jose Maria Cordova Intl - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Medellín Jose Maria Cordova Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $198 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Medellín Jose Maria Cordova Intl Airport for as low as $178 on momondo.

There are 3 cabin classes available to choose from on Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Copa Airlines and Avianca are the most popular carriers operating from Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl

Wingo, Copa Airlines and Avianca are the top three most popular airlines that fly to Panama City from Medellín Jose Maria Cordova Intl Airport according to our data. Wingo is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 3 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

Historically, on average around 2% of flights between Medellín and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 109 minutes.

Generally, flights departing in the evening tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Wednesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 2% of their flights experiencing any sort of delay.

The number of flights available between Medellín Jose Maria Cordova Intl Airport and Panama City is 13 per day as of April 2026. The most frequent departure time is 6:00PM, with 37% of daily flights leaving in the afternoon.

As of April 2026, there are 96 flights per week flying from Medellín Jose Maria Cordova Intl Airport to Panama City. The most common day of the week flights depart is Sat, with 19% of flights taking off on this day.