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Cheap flights from Harrisburg to Panama City from $522

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to Panama City departing on 4/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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United Airlines Logo
5:43 pm - 4:04 amMDT-PTY
11h 21m2 stops
United Airlines Logo
9:45 am - 9:38 amPTY-MDT
22h 53m2 stops
$522United Airlines
Find Deal
Sat, Apr 18 - Sat, Apr 25
American Airlines Logo
4:47 pm - 3:38 pmMDT-PTY
22h 51m2 stops
American Airlines Logo
2:27 pm - 10:54 amPTY-MDT
20h 27m2 stops
$539American Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 22
Delta Logo
6:00 am - 1:55 pmMDT-PTY
31h 55m2 stops
Delta Logo
3:20 pm - 11:00 pmPTY-MDT
31h 40m2 stops
$565Delta
Find Deal
Sun, Feb 22 - Thu, Feb 26
United Airlines Logo
5:40 pm - 1:45 pmMDT-PTY
21h 05m2 stops
United Airlines Logo
10:55 pm - 4:47 pmPTY-MDT
16h 52m2 stops
$568United Airlines
Find Deal
Tue, Mar 17 - Sat, Mar 28
American Airlines Logo
7:59 pm - 12:15 pmMDT-PTY
17h 16m2 stops
American Airlines Logo
1:55 pm - 10:59 amPTY-MDT
20h 04m2 stops
$573American Airlines
Find Deal
Sat, Apr 18 - Sun, Apr 26
Delta Logo
5:55 pm - 1:55 pmMDT-PTY
20h 00m1 stop
Delta Logo
3:20 pm - 11:00 pmPTY-MDT
31h 40m2 stops
$586Delta
Find Deal
Sun, Feb 22 - Thu, Feb 26
American Airlines Logo
4:47 pm - 1:27 pmMDT-PTY
20h 40m2 stops
American Airlines Logo
2:27 pm - 12:13 pmPTY-MDT
21h 46m2 stops
$599American Airlines
Find Deal
Wed, Jan 14 - Mon, Jan 26
American Airlines Logo
5:06 pm - 1:22 pmMDT-PTY
20h 16m2 stops
American Airlines Logo
4:05 pm - 10:57 amPTY-MDT
18h 52m2 stops
$632American Airlines
Find Deal
Sun, Feb 22 - Thu, Feb 26
American Airlines Logo
7:37 pm - 2:22 pmMDT-PTY
19h 45m2 stops
American Airlines Logo
1:44 pm - 10:52 pmPTY-MDT
8h 08m1 stop
$643American Airlines
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Tue, Mar 17 - Sat, Mar 28
United Airlines Logo
2:28 pm - 5:07 pmMDT-PTY
26h 39m2 stops
United Airlines Logo
4:41 pm - 10:13 amPTY-MDT
17h 32m2 stops
$652United Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 22

United Airlines flights from Harrisburg to Panama City

Our best United Airlines deals on Harrisburg to Panama City flight tickets
United Airlines
Apr 18
MDT5:43 pmHarrisburg
11h 21m
2 stops
PTY4:04 amPanama City Tocumen Intl
Apr 25
PTY9:45 amPanama City Tocumen Intl
22h 53m
2 stops
MDT9:38 amHarrisburg
$522
Find similar
United Airlines
Mar 17
MDT5:40 pmHarrisburg
21h 05m
2 stops
PTY1:45 pmPanama City Tocumen Intl
Mar 28
PTY10:55 pmPanama City Tocumen Intl
16h 52m
2 stops
MDT4:47 pmHarrisburg
$568
Find similar
United Airlines
Jan 15
MDT2:28 pmHarrisburg
26h 39m
2 stops
PTY5:07 pmPanama City Tocumen Intl
Jan 22
PTY4:41 pmPanama City Tocumen Intl
17h 32m
2 stops
MDT10:13 amHarrisburg
$652
Find similar

American Airlines flights from Harrisburg to Panama City

Our best American Airlines deals on Harrisburg to Panama City flight tickets
American Airlines
Jan 15
MDT4:47 pmHarrisburg
22h 51m
2 stops
PTY3:38 pmPanama City Tocumen Intl
Jan 22
PTY2:27 pmPanama City Tocumen Intl
20h 27m
2 stops
MDT10:54 amHarrisburg
$539
Find similar
American Airlines
Apr 18
MDT7:59 pmHarrisburg
17h 16m
2 stops
PTY12:15 pmPanama City Tocumen Intl
Apr 26
PTY1:55 pmPanama City Tocumen Intl
20h 04m
2 stops
MDT10:59 amHarrisburg
$573
Find similar
American Airlines
Jan 14
MDT4:47 pmHarrisburg
20h 40m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 26
PTY2:27 pmPanama City Tocumen Intl
21h 46m
2 stops
MDT12:13 pmHarrisburg
$599
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 2, 2025.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sat 4/18

5:43 pm-4:04 am

2 stops11h 21m

Panama City Tocumen Intl

Sat 4/25

9:45 am-9:38 am

2 stops22h 53m

$522

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 1/15

4:47 pm-3:38 pm

2 stops22h 51m

Panama City Tocumen Intl

Thu 1/22

2:27 pm-10:54 am

2 stops20h 27m

$539

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sun 2/22

6:00 am-1:55 pm

2 stops31h 55m

Panama City Tocumen Intl

Thu 2/26

3:20 pm-11:00 pm

2 stops31h 40m

$565

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 3/17

5:40 pm-1:45 pm

2 stops21h 05m

Panama City Tocumen Intl

Sat 3/28

10:55 pm-4:47 pm

2 stops16h 52m

$568

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sat 4/18

7:59 pm-12:15 pm

2 stops17h 16m

Panama City Tocumen Intl

Sun 4/26

1:55 pm-10:59 am

2 stops20h 04m

$573

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sun 2/22

5:55 pm-1:55 pm

1 stop20h 00m

Panama City Tocumen Intl

Thu 2/26

3:20 pm-11:00 pm

2 stops31h 40m

$586

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 1/14

4:47 pm-1:27 pm

2 stops20h 40m

Panama City Tocumen Intl

Mon 1/26

2:27 pm-12:13 pm

2 stops21h 46m

$599

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sun 2/22

5:06 pm-1:22 pm

2 stops20h 16m

Panama City Tocumen Intl

Thu 2/26

4:05 pm-10:57 am

2 stops18h 52m

$632

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 3/17

7:37 pm-2:22 pm

2 stops19h 45m

Panama City Tocumen Intl

Sat 3/28

1:44 pm-10:52 pm

1 stop8h 08m

$643

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 1/15

2:28 pm-5:07 pm

2 stops26h 39m

Panama City Tocumen Intl

Thu 1/22

4:41 pm-10:13 am

2 stops17h 32m

$652

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Panama City from

How to get the cheapest flight ticket from Harrisburg to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Harrisburg and Panama City?

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Saturday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $480. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $930. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Can stopping save me money on Harrisburg to Panama City flights?

You could potentially save up to 24% on your flight if you consider stops on a Harrisburg to Panama City flight.

When to book flights from Harrisburg to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Harrisburg to Panama City (MDT to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Panama City

Fastest flight time

10h 52m

Direct flights

None
The fastest flight from Harrisburg to Panama City takes 10h 52m
There are no direct flights from Harrisburg to Panama City. There are no popular flight routes from Harrisburg to Panama City.
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  • How far is Harrisburg to Panama City Tocumen Intl by plane?

    There are 2166.5 mi between Harrisburg and Panama City Tocumen Intl. In terms of flight time, this usually takes a little over 7h 55m.

  • When did momondo last update prices for flights from Harrisburg Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Harrisburg Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Harrisburg Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Harrisburg Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Harrisburg to Panama City?

Best airlines flying from Harrisburg to Panama City

Compare and see reviews for airlines that fly from Harrisburg to Panama City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $491Free CancellationRating
7.9
8,010 reviews
Search Delta flights
American AirlinesPriceFrom $501Free CancellationRating
7.2
11,041 reviews
Search American Airlines flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from Harrisburg.

Can I find flights from Harrisburg to Panama City with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Harrisburg to Panama City flights to just show those with flexible booking policies.

How can momondo help me find flights from Harrisburg to Panama City?

Once you have performed a search for Harrisburg to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Harrisburg to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Harrisburg to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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