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Cheap flights from Guayaquil to Panama City from $167

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guayaquil to Panama City departing on 1/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Guayaquil to Panama City

Cheap round-trip flights

Avianca Logo
3:35 am - 10:10 amGYE-PTY
6h 35m1 stop
Avianca Logo
10:05 pm - 8:35 amPTY-GYE
10h 30m1 stop
$320Avianca
Find Deal
Tue, Oct 14 - Sat, Oct 18
Avianca Logo
2:50 pm - 9:10 pmGYE-PTY
6h 20m1 stop
Avianca Logo
9:55 am - 5:20 pmPTY-GYE
7h 25m1 stop
$330Avianca
Find Deal
Mon, Sep 22 - Sat, Sep 27
Avianca Logo
3:35 am - 10:10 amGYE-PTY
6h 35m1 stop
Avianca Logo
5:55 pm - 1:05 amPTY-GYE
7h 10m1 stop
$332Avianca
Find Deal
Thu, Oct 23 - Mon, Oct 27
Avianca Logo
10:25 am - 4:55 pmGYE-PTY
6h 30m1 stop
Avianca Logo
2:55 am - 9:15 amPTY-GYE
6h 20m1 stop
$334Avianca
Find Deal
Fri, Nov 28 - Sat, Dec 6
Avianca Logo
4:40 am - 4:55 pmGYE-PTY
12h 15m1 stop
Avianca Logo
2:55 am - 9:15 amPTY-GYE
6h 20m1 stop
$335Avianca
Find Deal
Wed, Nov 26 - Tue, Dec 2
Copa Airlines Logo
6:33 pm - 8:41 pmGYE-PTY
2h 08mnonstop
Copa Airlines Logo
11:31 am - 1:46 pmPTY-GYE
2h 15mnonstop
$340Copa Airlines
Find Deal
Wed, Oct 15 - Fri, Oct 17
Copa Airlines Logo
8:30 am - 10:41 amGYE-PTY
2h 11mnonstop
Copa Airlines Logo
11:31 am - 1:46 pmPTY-GYE
2h 15mnonstop
$352Copa Airlines
Find Deal
Wed, Oct 22 - Sat, Oct 25
Copa Airlines Logo
2:35 pm - 4:46 pmGYE-PTY
2h 11mnonstop
Copa Airlines Logo
9:02 am - 11:18 amPTY-GYE
2h 16mnonstop
$362Copa Airlines
Find Deal
Wed, Nov 5 - Fri, Nov 7
Copa Airlines Logo
8:30 am - 10:41 amGYE-PTY
2h 11mnonstop
Copa Airlines Logo
11:17 am - 1:32 pmPTY-GYE
2h 15mnonstop
$374Copa Airlines
Find Deal
Thu, Oct 23 - Sun, Oct 26
Logo
12:15 pm - 2:27 pmGYE-PTY
2h 12mnonstop
Logo
5:25 pm - 10:40 pmPTY-GYE
5h 15m1 stop
$376
Find Deal
Wed, Oct 15 - Sat, Oct 18

Avianca flights from Guayaquil to Panama City

Our best Avianca deals on Guayaquil to Panama City flight tickets
Avianca
Sep 27
GYE3:35 amGuayaquil Jose Joaquin de Olmedo
6h 35m
1 stop
PTY10:10 amPanama City Tocumen Intl
Oct 4
PTY3:20 amPanama City Tocumen Intl
6h 35m
1 stop
GYE9:55 amGuayaquil Jose Joaquin de Olmedo
$320
Find similar
Avianca
Sep 22
GYE2:50 pmGuayaquil Jose Joaquin de Olmedo
6h 20m
1 stop
PTY9:10 pmPanama City Tocumen Intl
Sep 27
PTY9:55 amPanama City Tocumen Intl
7h 25m
1 stop
GYE5:20 pmGuayaquil Jose Joaquin de Olmedo
$330
Find similar
Avianca
Oct 23
GYE3:35 amGuayaquil Jose Joaquin de Olmedo
6h 35m
1 stop
PTY10:10 amPanama City Tocumen Intl
Oct 27
PTY5:55 pmPanama City Tocumen Intl
7h 10m
1 stop
GYE1:05 amGuayaquil Jose Joaquin de Olmedo
$332
Find similar

Copa Airlines flights from Guayaquil to Panama City

Our best Copa Airlines deals on Guayaquil to Panama City flight tickets
Copa Airlines
Oct 15
GYE6:33 pmGuayaquil Jose Joaquin de Olmedo
2h 08m
PTY8:41 pmPanama City Tocumen Intl
Oct 17
PTY11:31 amPanama City Tocumen Intl
2h 15m
GYE1:46 pmGuayaquil Jose Joaquin de Olmedo
$340
Find similar
Copa Airlines
Oct 22
GYE8:30 amGuayaquil Jose Joaquin de Olmedo
2h 11m
PTY10:41 amPanama City Tocumen Intl
Oct 25
PTY11:31 amPanama City Tocumen Intl
2h 15m
GYE1:46 pmGuayaquil Jose Joaquin de Olmedo
$352
Find similar
Copa Airlines
Nov 5
GYE2:35 pmGuayaquil Jose Joaquin de Olmedo
2h 11m
PTY4:46 pmPanama City Tocumen Intl
Nov 7
PTY9:02 amPanama City Tocumen Intl
2h 16m
GYE11:18 amGuayaquil Jose Joaquin de Olmedo
$362
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Guayaquil to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Guayaquil to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Tue 10/14

3:35 am-10:10 am

1 stop6h 35m

Panama City Tocumen Intl

Sat 10/18

10:05 pm-8:35 am

1 stop10h 30m

$320

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 9/22

2:50 pm-9:10 pm

1 stop6h 20m

Panama City Tocumen Intl

Sat 9/27

9:55 am-5:20 pm

1 stop7h 25m

$330

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 10/23

3:35 am-10:10 am

1 stop6h 35m

Panama City Tocumen Intl

Mon 10/27

5:55 pm-1:05 am

1 stop7h 10m

$332

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Fri 11/28

10:25 am-4:55 pm

1 stop6h 30m

Panama City Tocumen Intl

Sat 12/6

2:55 am-9:15 am

1 stop6h 20m

$334

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 11/26

4:40 am-4:55 pm

1 stop12h 15m

Panama City Tocumen Intl

Tue 12/2

2:55 am-9:15 am

1 stop6h 20m

$335

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 10/15

6:33 pm-8:41 pm

Nonstop2h 08m

Panama City Tocumen Intl

Fri 10/17

11:31 am-1:46 pm

Nonstop2h 15m

$340

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 10/22

8:30 am-10:41 am

Nonstop2h 11m

Panama City Tocumen Intl

Sat 10/25

11:31 am-1:46 pm

Nonstop2h 15m

$352

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 11/5

2:35 pm-4:46 pm

Nonstop2h 11m

Panama City Tocumen Intl

Fri 11/7

9:02 am-11:18 am

Nonstop2h 16m

$362

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 10/23

8:30 am-10:41 am

Nonstop2h 11m

Panama City Tocumen Intl

Sun 10/26

11:17 am-1:32 pm

Nonstop2h 15m

$374

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 10/15

12:15 pm-2:27 pm

Nonstop2h 12m

Panama City Tocumen Intl

Sat 10/18

5:25 pm-10:40 pm

1 stop5h 15m

$376

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Guayaquil to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, May is the cheapest month to fly from Guayaquil to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $246. If you’re not able to fly to Panama City in May, then June is your next best option. Flight prices from Guayaquil to Panama City during June average around $246.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Friday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $449. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $545. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Guayaquil to Panama City during this time can be as low as $430. Try not to purchase tickets at noon because they tend to be around $543. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl flight route?

Fly from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl for the best Guayaquil Jose Joaquin de Olmedo - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Guayaquil when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $290 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Guayaquil for as low as $251 on momondo.

What cabin class options are available on Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Guayaquil to Panama City flights?

You could potentially save up to 5% on your flight if you consider stops on a Guayaquil to Panama City flight.

How have Guayaquil to Panama City flight prices changed over time?

As of September 2025, prices for Guayaquil to Panama City flights are approximately 20% more expensive when compared to flights at the same time last year.

When to book flights from Guayaquil to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Guayaquil to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guayaquil to Panama City (GYE to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guayaquil to Panama City

Best Price Found

$261

Fastest flight time

2h 06m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Guayaquil in the past 72 hours is $261. The best round-trip flight deal from Guayaquil to Panama City found on momondo in the last 72 hours is $390.
The fastest flight from Guayaquil to Panama City takes 2h 06m
Direct flights go from Guayaquil to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 772.2 mi away from Guayaquil Jose Joaquin de Olmedo. Typically, this will take 2h 08m by plane in normal conditions.

  • When did momondo last update prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Guayaquil to Panama City?

  • What is the most popular airline from Guayaquil to Panama City?

Best airlines flying from Guayaquil to Panama City

Compare and see reviews for airlines that fly from Guayaquil to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $223Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights
AviancaPriceFrom $226Free CancellationRating
6.7
2,435 reviews
Search Avianca flights

  • Copa Airlines Flights From Guayaquil to Panama City

    Copa Airlines flies from Guayaquil to Panama City around 28 times per week, with 1,531 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Guayaquil to Panama City in the last 72 hours was $223 (round-trip), much lower than the average airfare cost of $350 for Copa Airlines flights on this route.

  • Avianca Flights From Guayaquil to Panama City

    Avianca (6.7/10 from 2,435 reviews) operates around 1 flight from Guayaquil to Panama City in any given week. The average Avianca airfare for this route is around $317, with deals from around $226 rare but found on momondo. Referenced prices are for round-trip Guayaquil to Panama City flight searches in the last 72 hours.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Guayaquil to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Guayaquil to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Guayaquil to Panama City with flexible booking policies on momondo?

All flight searches from Guayaquil to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Guayaquil to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Guayaquil. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Guayaquil to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Guayaquil are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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