Cheap flights from Guayaquil to Panama City from $188

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guayaquil to Panama City departing on 1/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Avianca Logo
3:35 pm - 12:40 amGYE-PTY
9h 05m1 stop
Avianca Logo
2:55 am - 9:15 amPTY-GYE
6h 20m1 stop
$339Avianca
Find Deal
Wed, Nov 19 - Wed, Nov 19
Avianca Logo
3:30 am - 8:50 amGYE-PTY
5h 20m1 stop
Avianca Logo
9:45 am - 5:45 pmPTY-GYE
8h 00m1 stop
$347Avianca
Find Deal
Wed, Nov 19 - Sun, Nov 23
Avianca Logo
4:40 am - 2:00 pmGYE-PTY
9h 20m1 stop
Avianca Logo
9:45 am - 5:45 pmPTY-GYE
8h 00m1 stop
$349Avianca
Find Deal
Wed, Nov 26 - Mon, Dec 1
Avianca Logo
6:55 pm - 1:00 amGYE-PTY
6h 05m1 stop
Avianca Logo
2:55 am - 2:25 pmPTY-GYE
11h 30m1 stop
$351Avianca
Find Deal
Thu, Nov 27 - Tue, Dec 2
Avianca Logo
3:30 am - 8:50 amGYE-PTY
5h 20m1 stop
Avianca Logo
9:45 am - 2:25 pmPTY-GYE
4h 40m1 stop
$352Avianca
Find Deal
Wed, Mar 11 - Mon, Mar 16
Copa Airlines Logo
2:35 pm - 4:42 pmGYE-PTY
2h 07mnonstop
Copa Airlines Logo
9:02 am - 11:18 amPTY-GYE
2h 16mnonstop
$383Copa Airlines
Find Deal
Wed, Feb 4 - Tue, Feb 10
Copa Airlines Logo
8:32 am - 10:41 amGYE-PTY
2h 09mnonstop
Copa Airlines Logo
11:17 am - 1:34 pmPTY-GYE
2h 17mnonstop
$395Copa Airlines
Find Deal
Thu, Mar 12 - Mon, Mar 16
Multiple Airlines Logo
2:35 pm - 4:46 pmGYE-PTY
2h 11mnonstop
Multiple Airlines Logo
9:45 am - 2:30 pmPTY-GYE
4h 45m1 stop
$399Multiple Airlines
Find Deal
Tue, Dec 9 - Thu, Dec 11
Copa Airlines Logo
12:21 pm - 2:32 pmGYE-PTY
2h 11mnonstop
Copa Airlines Logo
11:19 am - 1:36 pmPTY-GYE
2h 17mnonstop
$403Copa Airlines
Find Deal
Mon, Nov 24 - Wed, Nov 26
Copa Airlines Logo
8:34 am - 10:41 amGYE-PTY
2h 07mnonstop
Copa Airlines Logo
6:27 pm - 8:46 pmPTY-GYE
2h 19mnonstop
$415Copa Airlines
Find Deal
Sat, Jan 10 - Sun, Jan 25

Avianca flights from Guayaquil to Panama City

Our best Avianca deals on Guayaquil to Panama City flight tickets
Avianca
Nov 19
GYE3:35 pmGuayaquil Jose Joaquin de Olmedo
9h 05m
1 stop
PTY12:40 amPanama City Tocumen Intl
Nov 19
PTY2:55 amPanama City Tocumen Intl
6h 20m
1 stop
GYE9:15 amGuayaquil Jose Joaquin de Olmedo
Avianca
Nov 19
GYE3:30 amGuayaquil Jose Joaquin de Olmedo
5h 20m
1 stop
PTY8:50 amPanama City Tocumen Intl
Nov 23
PTY9:45 amPanama City Tocumen Intl
8h 00m
1 stop
GYE5:45 pmGuayaquil Jose Joaquin de Olmedo
Avianca
Nov 26
GYE4:40 amGuayaquil Jose Joaquin de Olmedo
9h 20m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Dec 1
PTY9:45 amPanama City Tocumen Intl
8h 00m
1 stop
GYE5:45 pmGuayaquil Jose Joaquin de Olmedo

Copa Airlines flights from Guayaquil to Panama City

Our best Copa Airlines deals on Guayaquil to Panama City flight tickets
Copa Airlines
Feb 4
GYE2:35 pmGuayaquil Jose Joaquin de Olmedo
2h 07m
PTY4:42 pmPanama City Tocumen Intl
Feb 10
PTY9:02 amPanama City Tocumen Intl
2h 16m
GYE11:18 amGuayaquil Jose Joaquin de Olmedo
Copa Airlines
Mar 12
GYE8:32 amGuayaquil Jose Joaquin de Olmedo
2h 09m
PTY10:41 amPanama City Tocumen Intl
Mar 16
PTY11:17 amPanama City Tocumen Intl
2h 17m
GYE1:34 pmGuayaquil Jose Joaquin de Olmedo
Copa Airlines
Nov 24
GYE12:21 pmGuayaquil Jose Joaquin de Olmedo
2h 11m
PTY2:32 pmPanama City Tocumen Intl
Nov 26
PTY11:19 amPanama City Tocumen Intl
2h 17m
GYE1:36 pmGuayaquil Jose Joaquin de Olmedo

momondo Fare Finder

 
Customize your flight search to find flights from Guayaquil to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Guayaquil to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

3:35 pm-12:40 am

1 stop9h 05m

Panama City Tocumen Intl

Wed 11/19

2:55 am-9:15 am

1 stop6h 20m

$339

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

3:30 am-8:50 am

1 stop5h 20m

Panama City Tocumen Intl

Sun 11/23

9:45 am-5:45 pm

1 stop8h 00m

$347

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 11/26

4:40 am-2:00 pm

1 stop9h 20m

Panama City Tocumen Intl

Mon 12/1

9:45 am-5:45 pm

1 stop8h 00m

$349

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 11/27

6:55 pm-1:00 am

1 stop6h 05m

Panama City Tocumen Intl

Tue 12/2

2:55 am-2:25 pm

1 stop11h 30m

$351

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 3/11

3:30 am-8:50 am

1 stop5h 20m

Panama City Tocumen Intl

Mon 3/16

9:45 am-2:25 pm

1 stop4h 40m

$352

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Wed 2/4

2:35 pm-4:42 pm

Nonstop2h 07m

Panama City Tocumen Intl

Tue 2/10

9:02 am-11:18 am

Nonstop2h 16m

$383

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Thu 3/12

8:32 am-10:41 am

Nonstop2h 09m

Panama City Tocumen Intl

Mon 3/16

11:17 am-1:34 pm

Nonstop2h 17m

$395

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Tue 12/9

2:35 pm-4:46 pm

Nonstop2h 11m

Panama City Tocumen Intl

Thu 12/11

9:45 am-2:30 pm

1 stop4h 45m

$399

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Mon 11/24

12:21 pm-2:32 pm

Nonstop2h 11m

Panama City Tocumen Intl

Wed 11/26

11:19 am-1:36 pm

Nonstop2h 17m

$403

GuayaquilPanama City

GYE - PTY

GYEPTY

Guayaquil Jose Joaquin de Olmedo

Sat 1/10

8:34 am-10:41 am

Nonstop2h 07m

Panama City Tocumen Intl

Sun 1/25

6:27 pm-8:46 pm

Nonstop2h 19m

$415

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Guayaquil to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Guayaquil and Panama City?

What is the cheapest month to fly to Panama City?

In general, May is the cheapest month to fly from Guayaquil to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $246. If you’re not able to fly to Panama City in May, then June is your next best option. Flight prices from Guayaquil to Panama City during June average around $246.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Friday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $455. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $536. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Guayaquil to Panama City during this time can be as low as $432. Try not to purchase tickets at noon because they tend to be around $552. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl flight route?

Fly from Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl for the best Guayaquil Jose Joaquin de Olmedo - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Guayaquil when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $295 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Guayaquil for as low as $251 on momondo.

What cabin class options are available on Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Guayaquil to Panama City flights?

You could potentially save up to 20% on your flight if you consider stops on a Guayaquil to Panama City flight.

How have Guayaquil to Panama City flight prices changed over time?

As of November 2025, prices for Guayaquil to Panama City flights are approximately 36% more expensive when compared to flights at the same time last year.

When to book flights from Guayaquil to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Guayaquil to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guayaquil to Panama City (GYE to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guayaquil to Panama City

Best Price Found

$285

Fastest flight time

2h 06m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Guayaquil in the past 72 hours is $285. The best round-trip flight deal from Guayaquil to Panama City found on momondo in the last 72 hours is $383.
The fastest flight from Guayaquil to Panama City takes 2h 06m
Direct flights go from Guayaquil to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
  • How far is Guayaquil Jose Joaquin de Olmedo to Panama City Tocumen Intl by plane?

    Panama City Tocumen Intl is 772.2 mi away from Guayaquil Jose Joaquin de Olmedo. Typically, this will take 2h 06m by plane in normal conditions.

  • When did momondo last update prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Guayaquil Jose Joaquin de Olmedo Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Guayaquil to Panama City?

  • What is the most popular airline from Guayaquil to Panama City?

Best airlines flying from Guayaquil to Panama City

Compare and see reviews for airlines that fly from Guayaquil to Panama City with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $225Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
AviancaPriceFrom $230Free CancellationRating
6.6
2,470 reviews
Search Avianca flights
  • Copa Airlines Flights From Guayaquil to Panama City

    Copa Airlines flies from Guayaquil to Panama City around 36 times per week, with 1,561 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Guayaquil to Panama City in the last 72 hours was $225 (round-trip), much lower than the average airfare cost of $375 for Copa Airlines flights on this route.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Guayaquil to Panama City?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Guayaquil to Panama City. momondo saves you time and could save you money on your trip.

Can I find flights from Guayaquil to Panama City with flexible booking policies on momondo?

All flight searches from Guayaquil to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Guayaquil to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Guayaquil. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Guayaquil to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Guayaquil are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Wed 12/3
Wed 12/10

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