Cheap flights from Houston George Bush Intcntl Airport to Panama City from $309

In general, March is the cheapest month to fly from Houston George Bush Intcntl Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $678. If you’re not able to fly to Panama City in March, then August is your next best option. Flight prices from Houston George Bush Intcntl Airport to Panama City during August average around $810.

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Houston George Bush Intcntl Airport to Panama City during this time can be as low as $873. Try not to purchase tickets in the morning because they tend to be around $920. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston George Bush Intcntl - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Houston George Bush Intcntl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $883 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Houston George Bush Intcntl Airport for as low as $778 on momondo.

There are 3 cabin classes available to choose from on Houston George Bush Intcntl Airport to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 62% on your flight if you consider stops on a Houston George Bush Intcntl Airport to Panama City flight.

Historically, on average around 17% of flights between Houston and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 136 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 17% of their flights experiencing any sort of delay.

The number of flights available between Houston George Bush Intcntl Airport and Panama City is 6 per day as of June 2026. The most frequent departure time is 9:00AM, with 66% of daily flights leaving at noon.

As of June 2026, there are 42 flights per week flying from Houston George Bush Intcntl Airport to Panama City. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.