Cheap flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra from $716

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra (DTW-VVI)

Cheap round-trip flights

 Logo
9:05 pm - 2:35 amDTW-VVI
29h 30m3 stops
 Logo
3:40 am - 12:25 amVVI-DTW
21h 45m2 stops
Sat, Nov 1 - Thu, Nov 13
 Logo
9:05 pm - 2:35 amDTW-VVI
29h 30m3 stops
 Logo
3:40 am - 8:22 amVVI-DTW
29h 42m3 stops
Sat, Nov 1 - Thu, Nov 13
 Logo
6:17 am - 2:35 amDTW-VVI
20h 18m2 stops
 Logo
3:40 am - 6:26 pmVVI-DTW
15h 46m2 stops
Sat, Nov 1 - Thu, Nov 13
 Logo
9:05 pm - 2:35 amDTW-VVI
29h 30m3 stops
 Logo
8:35 am - 8:00 amVVI-DTW
24h 25m2 stops
Sat, Nov 1 - Fri, Nov 14
 Logo
9:05 pm - 2:35 amDTW-VVI
29h 30m3 stops
 Logo
5:25 am - 12:25 amVVI-DTW
20h 00m3 stops
Sat, Nov 1 - Fri, Nov 14
 Logo
6:17 am - 2:35 amDTW-VVI
20h 18m2 stops
 Logo
8:35 am - 8:00 amVVI-DTW
24h 25m2 stops
Sat, Nov 1 - Fri, Nov 14

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sat 11/1

9:05 pm-2:35 am

3 stops29h 30m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/13

3:40 am-12:25 am

2 stops21h 45m

$716

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sat 11/1

9:05 pm-2:35 am

3 stops29h 30m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/13

3:40 am-8:22 am

3 stops29h 42m

$739

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sat 11/1

6:17 am-2:35 am

2 stops20h 18m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/13

3:40 am-6:26 pm

2 stops15h 46m

$749

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sat 11/1

9:05 pm-2:35 am

3 stops29h 30m

Santa Cruz de la Sierra Viru Viru Intl

Fri 11/14

8:35 am-8:00 am

2 stops24h 25m

$849

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sat 11/1

9:05 pm-2:35 am

3 stops29h 30m

Santa Cruz de la Sierra Viru Viru Intl

Fri 11/14

5:25 am-12:25 am

3 stops20h 00m

$903

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sat 11/1

6:17 am-2:35 am

2 stops20h 18m

Santa Cruz de la Sierra Viru Viru Intl

Fri 11/14

8:35 am-8:00 am

2 stops24h 25m

$915

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra (DTW to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Direct flights

None
There are no direct flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra.
  • How far is Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl by plane?

    A flight from Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl will travel around 4340.2 mi. In terms of flight time, this usually takes a little over 20h 18m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The necessary travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • How do I get Price Alerts for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra?

    Search flight deals from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Cruz de la Sierra?

It is quick and easy to find Detroit to Santa Cruz de la Sierra flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights from Detroit to Santa Cruz de la Sierra with flexible booking policies on momondo?

Flights from Detroit to Santa Cruz de la Sierra with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santa Cruz de la Sierra?

Once all potential Detroit to Santa Cruz de la Sierra flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Santa Cruz de la Sierra now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Cruz de la Sierra and let you know when they change.

An easier way to manage your Santa Cruz de la Sierra trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 9/2
Tue 9/9

Find better results for your trip to Bolivia