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Cheap flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra from $707

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra departing on 12/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:35 am - 2:35 amDTW-VVI
19h 00m2 stops
Multiple Airlines Logo
3:40 am - 9:03 pmVVI-DTW
18h 23m2 stops
$707Multiple Airlines
Find Deal
lun., dic. 1 - vie., dic. 5
Multiple Airlines Logo
9:53 pm - 4:35 amDTW-VVI
29h 42m3 stops
Multiple Airlines Logo
3:40 am - 12:19 amVVI-DTW
21h 39m2 stops
$812Multiple Airlines
Find Deal
lun., dic. 1 - vie., dic. 5
Multiple Airlines Logo
9:53 pm - 4:35 amDTW-VVI
29h 42m3 stops
Multiple Airlines Logo
3:40 am - 8:07 amVVI-DTW
29h 27m3 stops
$831Multiple Airlines
Find Deal
lun., dic. 1 - vie., dic. 5
United Airlines Logo
6:00 am - 10:50 pmDTW-VVI
16h 50m2 stops
United Airlines Logo
11:44 am - 8:59 amVVI-DTW
21h 15m2 stops
$862United Airlines
Find Deal
sáb., abr. 4 - mar., abr. 7
Multiple Airlines Logo
11:37 am - 4:50 amDTW-VVI
16h 13m1 stop
Multiple Airlines Logo
3:40 am - 10:08 amVVI-DTW
31h 28m2 stops
$928Multiple Airlines
Find Deal
lun., dic. 1 - vie., dic. 5
United Airlines Logo
6:00 am - 3:36 amDTW-VVI
20h 36m2 stops
United Airlines Logo
11:40 am - 10:02 amVVI-DTW
23h 22m2 stops
$967United Airlines
Find Deal
lun., dic. 1 - sáb., dic. 6
United Airlines Logo
9:26 am - 3:44 amDTW-VVI
42h 18m2 stops
United Airlines Logo
11:44 am - 1:16 pmVVI-DTW
25h 32m2 stops
$1,219United Airlines
Find Deal
dom., abr. 12 - mar., abr. 14
Copa Airlines Logo
6:00 am - 10:50 pmDTW-VVI
16h 50m2 stops
Copa Airlines Logo
1:15 am - 8:20 pmVVI-DTW
19h 05m2 stops
$1,655Copa Airlines
Find Deal
dom., abr. 12 - lun., abr. 13
Copa Airlines Logo
6:00 am - 10:50 pmDTW-VVI
16h 50m2 stops
Copa Airlines Logo
1:15 am - 6:51 pmVVI-DTW
17h 36m2 stops
$1,825Copa Airlines
Find Deal
sáb., abr. 4 - lun., abr. 6
Copa Airlines Logo
6:00 am - 10:50 pmDTW-VVI
16h 50m2 stops
Copa Airlines Logo
1:15 am - 10:09 pmVVI-DTW
20h 54m2 stops
$1,978Copa Airlines
Find Deal
sáb., abr. 4 - lun., abr. 6

United Airlines flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra flight tickets
United Airlines
Apr 4
DTW6:00 amDetroit Metropolitan Wayne County
16h 50m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 7
VVI11:44 amSanta Cruz de la Sierra Viru Viru Intl
21h 15m
2 stops
DTW8:59 amDetroit Metropolitan Wayne County
$862
Find similar
United Airlines
Dec 1
DTW6:00 amDetroit Metropolitan Wayne County
20h 36m
2 stops
VVI3:36 amSanta Cruz de la Sierra Viru Viru Intl
Dec 6
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
23h 22m
2 stops
DTW10:02 amDetroit Metropolitan Wayne County
$967
Find similar
United Airlines
Nov 1
DTW2:10 pmDetroit Metropolitan Wayne County
37h 26m
3 stops
VVI3:36 amSanta Cruz de la Sierra Viru Viru Intl
Nov 13
VVI11:40 amSanta Cruz de la Sierra Viru Viru Intl
37h 02m
2 stops
DTW11:42 pmDetroit Metropolitan Wayne County
$1,140
Find similar

Copa Airlines flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Our best Copa Airlines deals on Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra flight tickets
Copa Airlines
Apr 12
DTW6:00 amDetroit Metropolitan Wayne County
16h 50m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 13
VVI1:15 amSanta Cruz de la Sierra Viru Viru Intl
19h 05m
2 stops
DTW8:20 pmDetroit Metropolitan Wayne County
$1,655
Find similar
Copa Airlines
Apr 4
DTW6:00 amDetroit Metropolitan Wayne County
16h 50m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 6
VVI1:15 amSanta Cruz de la Sierra Viru Viru Intl
17h 36m
2 stops
DTW6:51 pmDetroit Metropolitan Wayne County
$1,825
Find similar
Copa Airlines
Apr 4
DTW6:00 amDetroit Metropolitan Wayne County
16h 50m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Apr 6
VVI1:15 amSanta Cruz de la Sierra Viru Viru Intl
20h 54m
2 stops
DTW10:09 pmDetroit Metropolitan Wayne County
$1,978
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 27, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

lun. 12/1

6:35 am-2:35 am

2 stops19h 00m

Santa Cruz de la Sierra Viru Viru Intl

vie. 12/5

3:40 am-9:03 pm

2 stops18h 23m

$707

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

lun. 12/1

9:53 pm-4:35 am

3 stops29h 42m

Santa Cruz de la Sierra Viru Viru Intl

vie. 12/5

3:40 am-12:19 am

2 stops21h 39m

$812

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

lun. 12/1

9:53 pm-4:35 am

3 stops29h 42m

Santa Cruz de la Sierra Viru Viru Intl

vie. 12/5

3:40 am-8:07 am

3 stops29h 27m

$831

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

sáb. 4/4

6:00 am-10:50 pm

2 stops16h 50m

Santa Cruz de la Sierra Viru Viru Intl

mar. 4/7

11:44 am-8:59 am

2 stops21h 15m

$862

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

lun. 12/1

11:37 am-4:50 am

1 stop16h 13m

Santa Cruz de la Sierra Viru Viru Intl

vie. 12/5

3:40 am-10:08 am

2 stops31h 28m

$928

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

lun. 12/1

6:00 am-3:36 am

2 stops20h 36m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 12/6

11:40 am-10:02 am

2 stops23h 22m

$967

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

dom. 4/12

9:26 am-3:44 am

2 stops42h 18m

Santa Cruz de la Sierra Viru Viru Intl

mar. 4/14

11:44 am-1:16 pm

2 stops25h 32m

$1,219

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

dom. 4/12

6:00 am-10:50 pm

2 stops16h 50m

Santa Cruz de la Sierra Viru Viru Intl

lun. 4/13

1:15 am-8:20 pm

2 stops19h 05m

$1,655

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

sáb. 4/4

6:00 am-10:50 pm

2 stops16h 50m

Santa Cruz de la Sierra Viru Viru Intl

lun. 4/6

1:15 am-6:51 pm

2 stops17h 36m

$1,825

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

sáb. 4/4

6:00 am-10:50 pm

2 stops16h 50m

Santa Cruz de la Sierra Viru Viru Intl

lun. 4/6

1:15 am-10:09 pm

2 stops20h 54m

$1,978

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra (DTW to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Direct flights

None
There are no direct flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl by plane?

    A flight from Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl will travel around 4340.2 mi. In terms of flight time, this usually takes a little over 15h 58m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The necessary travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • How do I get Price Alerts for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra?

    Search flight deals from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Cruz de la Sierra?

It is quick and easy to find Detroit to Santa Cruz de la Sierra flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights from Detroit to Santa Cruz de la Sierra with flexible booking policies on momondo?

Flights from Detroit to Santa Cruz de la Sierra with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santa Cruz de la Sierra?

Once all potential Detroit to Santa Cruz de la Sierra flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Santa Cruz de la Sierra now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Cruz de la Sierra and let you know when they change.

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