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Cheap flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra from $782

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:00 am - 2:30 am
DTW
-
VVI
21h 30m
2 stops
Multiple Airlines Logo
3:35 am - 11:59 pm
VVI
-
DTW
20h 24m
2 stops
$782Multiple Airlines
Mon, May 18 - Mon, Jun 1
United Airlines Logo
9:00 am - 3:31 am
DTW
-
VVI
18h 31m
2 stops
United Airlines Logo
11:47 am - 11:43 pm
VVI
-
DTW
35h 56m
3 stops
$833United Airlines
Mon, May 18 - Tue, Jun 2
Multiple Airlines Logo
10:16 am - 4:35 am
DTW
-
VVI
41h 19m
2 stops
Multiple Airlines Logo
5:20 am - 9:39 pm
VVI
-
DTW
16h 19m
2 stops
$1,000Multiple Airlines
Sun, Feb 22 - Tue, Mar 10
Copa Airlines Logo
11:00 am - 3:31 am
DTW
-
VVI
16h 31m
2 stops
Copa Airlines Logo
1:12 am - 10:12 pm
VVI
-
DTW
21h 00m
2 stops
$1,053Copa Airlines
Sun, Jun 14 - Sat, Jun 20
Multiple Airlines Logo
5:09 am - 4:35 am
DTW
-
VVI
46h 26m
3 stops
Multiple Airlines Logo
5:20 am - 9:39 pm
VVI
-
DTW
16h 19m
2 stops
$1,086Multiple Airlines
Sun, Feb 22 - Tue, Mar 10
Multiple Airlines Logo
12:36 pm - 4:50 am
DTW
-
VVI
15h 14m
1 stop
Multiple Airlines Logo
3:40 am - 12:29 am
VVI
-
DTW
20h 49m
2 stops
$1,140Multiple Airlines
Sun, Feb 22 - Mon, Mar 9
United Airlines Logo
6:05 am - 10:50 pm
DTW
-
VVI
15h 45m
2 stops
United Airlines Logo
11:44 am - 11:59 pm
VVI
-
DTW
37h 15m
2 stops
$1,173United Airlines
Tue, Feb 24 - Thu, Feb 26
United Airlines Logo
6:05 am - 10:50 pm
DTW
-
VVI
15h 45m
2 stops
United Airlines Logo
11:44 am - 8:13 pm
VVI
-
DTW
33h 29m
2 stops
$1,183United Airlines
Tue, Feb 24 - Thu, Feb 26
Multiple Airlines Logo
8:00 am - 2:30 am
DTW
-
VVI
18h 30m
2 stops
Multiple Airlines Logo
3:35 am - 11:59 pm
VVI
-
DTW
20h 24m
2 stops
$1,203Multiple Airlines
Sat, Jul 25 - Mon, Aug 3
Multiple Airlines Logo
6:00 am - 4:45 am
DTW
-
VVI
21h 45m
3 stops
Multiple Airlines Logo
2:45 pm - 9:00 pm
VVI
-
DTW
30h 15m
3 stops
$1,302Multiple Airlines
Sun, Feb 22 - Tue, Mar 10

United Airlines flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Our best United Airlines deals on Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra flight tickets
United Airlines
May 18
DTW9:00 amDetroit Metropolitan Wayne County
18h 31m
2 stops
VVI3:31 amSanta Cruz de la Sierra Viru Viru Intl
Jun 2
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
35h 56m
3 stops
DTW11:43 pmDetroit Metropolitan Wayne County
$833
United Airlines
Feb 24
DTW6:05 amDetroit Metropolitan Wayne County
15h 45m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Feb 26
VVI11:44 amSanta Cruz de la Sierra Viru Viru Intl
37h 15m
2 stops
DTW11:59 pmDetroit Metropolitan Wayne County
$1,173
United Airlines
Feb 24
DTW6:05 amDetroit Metropolitan Wayne County
15h 45m
2 stops
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
Feb 26
VVI11:44 amSanta Cruz de la Sierra Viru Viru Intl
33h 29m
2 stops
DTW8:13 pmDetroit Metropolitan Wayne County
$1,183

Copa Airlines flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Our best Copa Airlines deals on Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra flight tickets
Copa Airlines
Jun 14
DTW11:00 amDetroit Metropolitan Wayne County
16h 31m
2 stops
VVI3:31 amSanta Cruz de la Sierra Viru Viru Intl
Jun 20
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
21h 00m
2 stops
DTW10:12 pmDetroit Metropolitan Wayne County
$1,053
Copa Airlines
Jul 25
DTW6:00 amDetroit Metropolitan Wayne County
16h 40m
2 stops
VVI10:40 pmSanta Cruz de la Sierra Viru Viru Intl
Aug 4
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
22h 31m
2 stops
DTW11:43 pmDetroit Metropolitan Wayne County
$1,614
Copa Airlines
Jul 24
DTW6:00 amDetroit Metropolitan Wayne County
16h 40m
2 stops
VVI10:40 pmSanta Cruz de la Sierra Viru Viru Intl
Aug 4
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
22h 31m
2 stops
DTW11:43 pmDetroit Metropolitan Wayne County
$1,647

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Mon 5/18

5:00 am-2:30 am

2 stops21h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 6/1

3:35 am-11:59 pm

2 stops20h 24m

$782

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Mon 5/18

9:00 am-3:31 am

2 stops18h 31m

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/2

11:47 am-11:43 pm

3 stops35h 56m

$833

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sun 2/22

10:16 am-4:35 am

2 stops41h 19m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

5:20 am-9:39 pm

2 stops16h 19m

$1,000

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sun 6/14

11:00 am-3:31 am

2 stops16h 31m

Santa Cruz de la Sierra Viru Viru Intl

Sat 6/20

1:12 am-10:12 pm

2 stops21h 00m

$1,053

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sun 2/22

5:09 am-4:35 am

3 stops46h 26m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

5:20 am-9:39 pm

2 stops16h 19m

$1,086

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sun 2/22

12:36 pm-4:50 am

1 stop15h 14m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

3:40 am-12:29 am

2 stops20h 49m

$1,140

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Tue 2/24

6:05 am-10:50 pm

2 stops15h 45m

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/26

11:44 am-11:59 pm

2 stops37h 15m

$1,173

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Tue 2/24

6:05 am-10:50 pm

2 stops15h 45m

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/26

11:44 am-8:13 pm

2 stops33h 29m

$1,183

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sat 7/25

8:00 am-2:30 am

2 stops18h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/3

3:35 am-11:59 pm

2 stops20h 24m

$1,203

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Sun 2/22

6:00 am-4:45 am

3 stops21h 45m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/10

2:45 pm-9:00 pm

3 stops30h 15m

$1,302

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra (DTW to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Fastest flight time

16h 16m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra takes 16h 16m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra.
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl by plane?

    A flight from Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl will travel around 4340.2 mi. In terms of flight time, this usually takes a little over 16h 16m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The necessary travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • How do I get Price Alerts for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra?

    Search flight deals from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Cruz de la Sierra?

It is quick and easy to find Detroit to Santa Cruz de la Sierra flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights from Detroit to Santa Cruz de la Sierra with flexible booking policies on momondo?

Flights from Detroit to Santa Cruz de la Sierra with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santa Cruz de la Sierra?

Once all potential Detroit to Santa Cruz de la Sierra flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Santa Cruz de la Sierra now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Cruz de la Sierra and let you know when they change.

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