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Cheap flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra from $560

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra departing on 6/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:47 pm - 11:10 am
DTW
-
VVI
39h 23m
2 stops
Multiple Airlines Logo
12:05 pm - 6:38 pm
VVI
-
DTW
30h 33m
2 stops
$999Multiple Airlines
Tue, Jun 16 - Tue, Jun 23
United Airlines Logo
6:15 am - 10:38 pm
DTW
-
VVI
40h 23m
2 stops
United Airlines Logo
11:47 am - 11:57 pm
VVI
-
DTW
36h 10m
3 stops
$1,058United Airlines
Tue, Jun 16 - Tue, Jun 23
Multiple Airlines Logo
6:30 am - 2:30 am
DTW
-
VVI
20h 00m
3 stops
Multiple Airlines Logo
3:35 am - 12:44 am
VVI
-
DTW
21h 09m
3 stops
$1,081Multiple Airlines
Tue, Jun 16 - Mon, Jun 22
Avianca Logo
6:00 am - 2:30 am
DTW
-
VVI
20h 30m
2 stops
Avianca Logo
3:40 am - 3:12 pm
VVI
-
DTW
35h 32m
2 stops
$1,427Avianca
Fri, Oct 23 - Sat, Oct 24

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Tue 6/16

7:47 pm-11:10 am

2 stops39h 23m

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/23

12:05 pm-6:38 pm

2 stops30h 33m

$999

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Tue 6/16

6:15 am-10:38 pm

2 stops40h 23m

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/23

11:47 am-11:57 pm

3 stops36h 10m

$1,058
Quickest round-trip

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Tue 6/16

6:30 am-2:30 am

3 stops20h 00m

Santa Cruz de la Sierra Viru Viru Intl

Mon 6/22

3:35 am-12:44 am

3 stops21h 09m

$1,081

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Fri 10/23

6:00 am-2:30 am

2 stops20h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/24

3:40 am-3:12 pm

2 stops35h 32m

$1,427
Cheapest one-way
Quickest one-way

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Mon 6/15

6:15 am-10:38 pm

2 stops16h 23m

$560

DetroitSanta Cruz de la Sierra

DTW - VVI

DTWVVI

Detroit Metropolitan Wayne County

Mon 6/1

6:15 am-3:31 am

2 stops21h 16m

$685

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santa Cruz de la Sierra from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl?

United Airlines is the most popular carrier operating from Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl

When to book flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra (DTW to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

Fastest flight time

39h 23m

Direct flights

None
The fastest flight from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra takes 39h 23m
There are no direct flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra. There are no popular flight routes from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra.
Search flight deals

Frequently asked questions about flying from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra

  • How far is Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl by plane?

    A flight from Detroit Metropolitan Wayne County to Santa Cruz de la Sierra Viru Viru Intl will travel around 4340.2 mi. In terms of flight time, this usually takes a little over 39h 23m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The necessary travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Cruz de la Sierra?

It is quick and easy to find Detroit to Santa Cruz de la Sierra flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santa Cruz de la Sierra that suits you.

Can I find flights from Detroit to Santa Cruz de la Sierra with flexible booking policies on momondo?

Flights from Detroit to Santa Cruz de la Sierra with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Detroit to Santa Cruz de la Sierra?

Once all potential Detroit to Santa Cruz de la Sierra flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Detroit to Santa Cruz de la Sierra now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Cruz de la Sierra and let you know when they change.

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Sun 6/21
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