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Cheap flights from Cali to Panama City from $156

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cali to Panama City departing on 10/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Copa Airlines Logo
3:23 pm - 4:54 pmCLO-PTY
1h 31mnonstop
Copa Airlines Logo
12:43 pm - 2:21 pmPTY-CLO
1h 38mnonstop
$276Copa Airlines
Find Deal
vie., sep. 26 - mar., sep. 30
Avianca Logo
6:50 pm - 12:10 amCLO-PTY
5h 20m1 stop
Avianca Logo
3:20 am - 8:18 amPTY-CLO
4h 58m1 stop
$279Avianca
Find Deal
jue., sep. 25 - sáb., sep. 27
Avianca Logo
9:50 am - 2:00 pmCLO-PTY
4h 10m1 stop
Avianca Logo
9:45 am - 2:45 pmPTY-CLO
5h 00m1 stop
$281Avianca
Find Deal
vie., oct. 31 - lun., nov. 3
Copa Airlines Logo
12:04 pm - 1:36 pmCLO-PTY
1h 32mnonstop
Copa Airlines Logo
9:20 am - 11:01 amPTY-CLO
1h 41mnonstop
$287Copa Airlines
Find Deal
lun., dic. 1 - vie., dic. 5
Copa Airlines Logo
12:04 pm - 1:36 pmCLO-PTY
1h 32mnonstop
Copa Airlines Logo
3:47 pm - 5:37 pmPTY-CLO
1h 50mnonstop
$293Copa Airlines
Find Deal
vie., nov. 28 - jue., ene. 15
Copa Airlines Logo
12:01 pm - 1:32 pmCLO-PTY
1h 31mnonstop
Copa Airlines Logo
9:20 am - 11:00 amPTY-CLO
1h 40mnonstop
$304Copa Airlines
Find Deal
mar., sep. 30 - vie., ene. 2
Avianca Logo
7:24 pm - 12:10 amCLO-PTY
4h 46m1 stop
Avianca Logo
2:55 pm - 11:40 pmPTY-CLO
8h 45m1 stop
$307Avianca
Find Deal
mar., sep. 30 - vie., oct. 31
Copa Airlines Logo
4:52 am - 6:24 amCLO-PTY
1h 32mnonstop
Copa Airlines Logo
3:47 pm - 5:29 pmPTY-CLO
1h 42mnonstop
$311Copa Airlines
Find Deal
dom., nov. 2 - vie., nov. 7
Avianca Logo
12:40 pm - 4:55 pmCLO-PTY
4h 15m1 stop
Avianca Logo
9:45 am - 2:45 pmPTY-CLO
5h 00m1 stop
$314Avianca
Find Deal
sáb., feb. 28 - mié., mar. 4
Logo
8:48 am - 10:20 amCLO-PTY
1h 32mnonstop
Logo
2:55 am - 7:10 amPTY-CLO
4h 15m1 stop
$320
Find Deal
vie., dic. 5 - lun., dic. 8

Copa Airlines flights from Cali to Panama City

Our best Copa Airlines deals on Cali to Panama City flight tickets
Copa Airlines
Sep 26
CLO12:01 pmCali Alfonso B. Aragon Intl
1h 31m
PTY1:32 pmPanama City Tocumen Intl
Sep 30
PTY12:43 pmPanama City Tocumen Intl
1h 38m
CLO2:21 pmCali Alfonso B. Aragon Intl
$276
Find similar
Copa Airlines
Dec 1
CLO12:04 pmCali Alfonso B. Aragon Intl
1h 32m
PTY1:36 pmPanama City Tocumen Intl
Dec 5
PTY9:20 amPanama City Tocumen Intl
1h 41m
CLO11:01 amCali Alfonso B. Aragon Intl
$287
Find similar
Copa Airlines
Nov 28
CLO12:04 pmCali Alfonso B. Aragon Intl
1h 32m
PTY1:36 pmPanama City Tocumen Intl
Jan 15
PTY3:47 pmPanama City Tocumen Intl
1h 50m
CLO5:37 pmCali Alfonso B. Aragon Intl
$293
Find similar

Avianca flights from Cali to Panama City

Our best Avianca deals on Cali to Panama City flight tickets
Avianca
Sep 25
CLO6:50 pmCali Alfonso B. Aragon Intl
5h 20m
1 stop
PTY12:10 amPanama City Tocumen Intl
Sep 27
PTY3:20 amPanama City Tocumen Intl
4h 58m
1 stop
CLO8:18 amCali Alfonso B. Aragon Intl
$279
Find similar
Avianca
Oct 31
CLO9:50 amCali Alfonso B. Aragon Intl
4h 10m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Nov 3
PTY9:45 amPanama City Tocumen Intl
5h 00m
1 stop
CLO2:45 pmCali Alfonso B. Aragon Intl
$281
Find similar
Avianca
Sep 30
CLO7:24 pmCali Alfonso B. Aragon Intl
4h 46m
1 stop
PTY12:10 amPanama City Tocumen Intl
Oct 31
PTY2:55 pmPanama City Tocumen Intl
8h 45m
1 stop
CLO11:40 pmCali Alfonso B. Aragon Intl
$307
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cali to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Cali to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

vie. 9/26

3:23 pm-4:54 pm

Nonstop1h 31m

Panama City Tocumen Intl

mar. 9/30

12:43 pm-2:21 pm

Nonstop1h 38m

$276

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

jue. 9/25

6:50 pm-12:10 am

1 stop5h 20m

Panama City Tocumen Intl

sáb. 9/27

3:20 am-8:18 am

1 stop4h 58m

$279

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

vie. 10/31

9:50 am-2:00 pm

1 stop4h 10m

Panama City Tocumen Intl

lun. 11/3

9:45 am-2:45 pm

1 stop5h 00m

$281

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

lun. 12/1

12:04 pm-1:36 pm

Nonstop1h 32m

Panama City Tocumen Intl

vie. 12/5

9:20 am-11:01 am

Nonstop1h 41m

$287

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

vie. 11/28

12:04 pm-1:36 pm

Nonstop1h 32m

Panama City Tocumen Intl

jue. 1/15

3:47 pm-5:37 pm

Nonstop1h 50m

$293

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

mar. 9/30

12:01 pm-1:32 pm

Nonstop1h 31m

Panama City Tocumen Intl

vie. 1/2

9:20 am-11:00 am

Nonstop1h 40m

$304

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

mar. 9/30

7:24 pm-12:10 am

1 stop4h 46m

Panama City Tocumen Intl

vie. 10/31

2:55 pm-11:40 pm

1 stop8h 45m

$307

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

dom. 11/2

4:52 am-6:24 am

Nonstop1h 32m

Panama City Tocumen Intl

vie. 11/7

3:47 pm-5:29 pm

Nonstop1h 42m

$311

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

sáb. 2/28

12:40 pm-4:55 pm

1 stop4h 15m

Panama City Tocumen Intl

mié. 3/4

9:45 am-2:45 pm

1 stop5h 00m

$314

CaliPanama City

CLO - PTY

CLOPTY

Cali Alfonso B. Aragon Intl

vie. 12/5

8:48 am-10:20 am

Nonstop1h 32m

Panama City Tocumen Intl

lun. 12/8

2:55 am-7:10 am

1 stop4h 15m

$320

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Cali to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, March is the cheapest month to fly from Cali to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $168. If you’re not able to fly to Panama City in March, then May is your next best option. Flight prices from Cali to Panama City during May average around $179.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Thursday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $415. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $457. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is at noon. Flights from Cali to Panama City during this time can be as low as $272. Try not to purchase tickets in the afternoon because they tend to be around $471. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl flight route?

Fly from Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl for the best Cali Alfonso B. Aragon Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Cali when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $199 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Cali for as low as $164 on momondo.

What cabin class options are available on Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Cali to Panama City flights?

No. A direct flight is the cheapest option for a flight between Cali to Panama City.

How have Cali to Panama City flight prices changed over time?

As of September 2025, prices for Cali to Panama City flights are approximately 25% more expensive when compared to flights at the same time last year.

When to book flights from Cali to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Cali to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cali to Panama City (CLO to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cali to Panama City

Best Price Found

$234

Fastest flight time

1h 31m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Cali in the past 72 hours is $234. The best round-trip flight deal from Cali to Panama City found on momondo in the last 72 hours is $333.
The fastest flight from Cali to Panama City takes 1h 31m
Direct flights go from Cali to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is Cali Alfonso B. Aragon Intl to Panama City Tocumen Intl by plane?

    Cali Alfonso B. Aragon Intl and Panama City Tocumen Intl are 433.7 mi apart from one another. A reasonable flight in good conditions will take 1h 31m.

  • When did momondo last update prices for flights from Cali Alfonso B. Aragon Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Cali Alfonso B. Aragon Intl Airport to Panama City Tocumen Intl Airport were last updated today.

  • How many operators does momondo search for flights from Cali Alfonso B. Aragon Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Cali Alfonso B. Aragon Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cali Alfonso B. Aragon Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The necessary travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Cali to Panama City?

  • What is the most popular airline from Cali to Panama City?

Best airlines flying from Cali to Panama City

Compare and see reviews for airlines that fly from Cali to Panama City with momondo
Airline
Rating
Free Cancellation
Price
WingoPriceFrom $97Free CancellationRating
7.3
136 reviews
Search Wingo flights
AviancaPriceFrom $146Free CancellationRating
6.7
2,435 reviews
Search Avianca flights
Copa AirlinesPriceFrom $159Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights

  • Copa Airlines Flights From Cali to Panama City

    The lowest priced Copa Airlines flight from Cali to Panama City from the last 72 hours was $159. Generally, Copa Airlines has 26 flights on this route every week with an average price of $286. Copa Airlines is rated 7.6/10 by our users.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Cali to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Cali to Panama City for you.

Can I find flights from Cali to Panama City with flexible booking policies on momondo?

All flight searches from Cali to Panama City on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Cali to Panama City?

Once all potential Cali to Panama City flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Cali to Panama City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama City from Cali. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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