Situated between St. Louis, Mo, and Effingham, IL, in the heart of central and southern Illinois, a comfortable, clean, affordable stay in a charming town is offered at our Greenville hotel. SureStay by Best Western Greenville is situated nearby local attractions such as the American Farm Heritage Museum, DuMoulin Museum, and Carlyle Lake. Easy access to I-170 ensures that you're always less than an hour away from the busy city of St. Louis. Whether you stay in the quaint town of Greenville for a relaxing getaway or head off to the city for an exciting excursion, you'll find our hotel is a convenient location. Comfortable king and queen-sized beds and simple décor ensure a welcoming environment in each room. In-room movies, rooms with spas (by request), refrigerators, hair dryers, and desk areas are only a few of the amenities we offer. Sofa beds, rollaway beds, and cribs are also available for larger groups or families to accommodate their stay. Whether your travel itinerary is jam-packed or you're looking for a relaxing stay, you'll find a long list of hotel amenities you can take advantage of. An onsite restaurant and complimentary continental breakfast ensure you never leave the hotel hungry. An indoor pool provides an area to destress at the end of each day. Free 24-hour parking for any vehicle (including trucks and RVs) is yet another benefit of a stay at our hotel. Our Greenville, IL hotel provides all the amenities you could want and more at a budget-friendly price.